Search Results - "MATRIX"

Alterations of matrisome gene expression in multipotent mesenchymal stromal cells under physiological hypoxia in vitro.

Authors: Matveeva D Andreeva E Rudimova Y et al.

Source: Tissue & cell [Tissue Cell] 2025 Dec; Vol. 97, pp. 103064. Date of Electronic Publication: 2025 Jul 30.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH Terms: Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Gene Expression Regulation* , Extracellular Matrix Proteins*/genetics , Extracellular Matrix Proteins*/biosynthesis , Extracellular Matrix Proteins*/metabolism , Extracellular Matrix*/metabolism , Extracellular Matrix*/genetics, Humans ; Cell Hypoxia/genetics ; Adipose Tissue/cytology ; Adipose Tissue/metabolism ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 1/metabolism ; Matrix Metalloproteinase 1/genetics

The role of MMPs and TIMPs in regenerative medicine: From pathological ECM remodeling to therapeutic applications.

Authors: Kazemi A Fathy M Jahanian A et al.

Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Oct; Vol. 191, pp. 118457. Date of Electronic Publication: 2025 Aug 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH Terms: Regenerative Medicine*/methods , Matrix Metalloproteinases*/metabolism , Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Tissue Inhibitor of Metalloproteinases*/metabolism, Humans ; Animals ; Tissue Engineering/methods ; Matrix Metalloproteinase Inhibitors/therapeutic use ; Matrix Metalloproteinase Inhibitors/pharmacology

The Coordinated Interplay Between MMP13 and Pro-Migratory MMPs in Collective Cell Migration of Zebrafish Keratocytes.

Authors: Uppalapati CK Jeffery MA Pascual AS et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 19; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Cell Movement*/drug effects , Matrix Metalloproteinase 13*/metabolism , Matrix Metalloproteinase 13*/genetics , Zebrafish Proteins*/metabolism , Zebrafish Proteins*/genetics, Animals ; Zebrafish/metabolism ; Cell Proliferation ; Wound Healing ; Matrix Metalloproteinases/metabolism ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase Inhibitors/pharmacology ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase 9/genetics

Effects of dengue virus type-2 serotype (DENV-2) on the expression profile of matrix metalloproteinases in THP-1, monocyte cells and their roles in endothelial dysfunctions: protective effect of atorvastatin.

Authors: Niranjan R Vidhyapriya P Murugasamy V et al.

Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Oct 20; Vol. 15, pp. 1632634. Date of Electronic Publication: 2025 Oct 20 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

MeSH Terms: Atorvastatin*/pharmacology , Monocytes*/virology , Monocytes*/drug effects , Monocytes*/metabolism , Dengue Virus*/drug effects , Dengue Virus*/classification , Matrix Metalloproteinases*/metabolism , Matrix Metalloproteinases*/genetics , Endothelial Cells*/drug effects , Endothelial Cells*/virology, Humans ; Animals ; Mice ; Dengue/virology ; Dengue/drug therapy ; THP-1 Cells ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase 9/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Serogroup ; Disease Models, Animal ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Gene Expression Profiling ; Matrix Metalloproteinase 14/genetics ; Matrix Metalloproteinase 14/metabolism

From Protein Misfolding to Extracellular Matrix Disorganisation: Understanding Disease Pathology in Rare Skeletal Dysplasias.

Authors: Dennis EP Briggs MD

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 15; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Osteochondrodysplasias*/metabolism , Osteochondrodysplasias*/pathology , Osteochondrodysplasias*/genetics , Achondroplasia*/metabolism , Achondroplasia*/pathology , Achondroplasia*/genetics , Protein Folding*, Humans ; Cartilage Oligomeric Matrix Protein/genetics ; Cartilage Oligomeric Matrix Protein/metabolism ; Animals ; Matrilin Proteins/genetics ; Matrilin Proteins/metabolism ; Chondrocytes/metabolism ; Chondrocytes/pathology ; Extracellular Matrix Proteins/metabolism ; Extracellular Matrix Proteins/genetics ; Growth Plate/metabolism ; Growth Plate/pathology ; Mutation

SCR Disease Name: Pseudoachondroplasia

Peripheral Blood Expression of MMPs and DNA Methylation-Related Genes in Women with Recurrent Spontaneous Abortion: A Case-Control Study.

Authors: Imani M Zare F Hadinedoushan H et al.

Source: F1000Research [F1000Res] 2025 Oct 06; Vol. 14, pp. 763. Date of Electronic Publication: 2025 Oct 06 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: F1000 Research Ltd Country of Publication: England NLM ID: 101594320 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-1402 (Electronic) Linking ISSN: 20461402 NLM ISO Abbreviation: F1000Res Subsets: MEDLINE

MeSH Terms: Abortion, Habitual*/genetics , Abortion, Habitual*/blood , DNA Methylation*/genetics , Matrix Metalloproteinases*/blood , Matrix Metalloproteinases*/genetics, Humans ; Female ; Adult ; Case-Control Studies ; Pregnancy ; DNA Methyltransferase 3A ; DNA (Cytosine-5-)-Methyltransferase 1/genetics ; Methylenetetrahydrofolate Reductase (NADPH2)/genetics ; Methylenetetrahydrofolate Reductase (NADPH2)/blood ; Matrix Metalloproteinase 9/blood ; Matrix Metalloproteinase 9/genetics ; DNA (Cytosine-5-)-Methyltransferases/genetics ; DNA (Cytosine-5-)-Methyltransferases/blood ; Matrix Metalloproteinase 2/blood ; Matrix Metalloproteinase 2/genetics ; Young Adult

Highly porous cryogel composed of bone matrix derived dECM and laponite for vascularized bone regeneration.

Authors: Wang X Shi Y Li X et al.

Source: Biomedical materials (Bristol, England) [Biomed Mater] 2025 Oct 17; Vol. 20 (6). Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101285195 Publication Model: Electronic Cited Medium: Internet ISSN: 1748-605X (Electronic) Linking ISSN: 17486041 NLM ISO Abbreviation: Biomed Mater Subsets: MEDLINE

MeSH Terms: Bone Regeneration* , Silicates*/chemistry , Cryogels*/chemistry , Bone Matrix*/chemistry , Decellularized Extracellular Matrix*/chemistry, Animals ; Rats ; Tissue Scaffolds/chemistry ; Osteogenesis ; Porosity ; Tissue Engineering/methods ; Rats, Sprague-Dawley ; Compressive Strength ; Biocompatible Materials/chemistry ; Cell Differentiation ; Humans ; Extracellular Matrix/chemistry ; Materials Testing ; Male ; Skull

Unraveling the matrisome signatures of quiescent and activated muscle stem cells.

Authors: Guillon E Bacar H Gilquin L et al.

Source: Stem cell reports [Stem Cell Reports] 2025 Oct 14; Vol. 20 (10), pp. 102635. Date of Electronic Publication: 2025 Sep 11.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/genetics , Muscle, Skeletal*/cytology , Muscle, Skeletal*/metabolism , Stem Cells*/metabolism , Stem Cells*/cytology, Animals ; Mice ; Basement Membrane/metabolism ; Stem Cell Niche ; Gene Expression Profiling ; Transcriptome ; Extracellular Matrix Proteins/metabolism ; Extracellular Matrix Proteins/genetics

Stressed β-cells contribute to loss of peri-islet extracellular matrix in type 1 diabetes.

Authors: Johansen CG Lam K Farnsworth NL

Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Oct 10; Vol. 16, pp. 1675043. Date of Electronic Publication: 2025 Oct 10 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 1*/pathology , Diabetes Mellitus, Type 1*/metabolism , Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Insulin-Secreting Cells*/pathology , Insulin-Secreting Cells*/metabolism , Islets of Langerhans*/metabolism , Islets of Langerhans*/pathology, Animals ; Mice ; Mice, Inbred NOD ; Humans ; Matrix Metalloproteinase 3/metabolism ; Matrix Metalloproteinase 3/genetics ; Female ; Male ; Hyperglycemia/metabolism ; Hyperglycemia/pathology ; Collagen Type IV/metabolism

Arazyme prevents skin aging through regulation of matrix metalloproteinase and collagen synthesis.

Authors: Kim JH Lee H Son KH et al.

Source: Enzyme and microbial technology [Enzyme Microb Technol] 2025 Oct; Vol. 190, pp. 110695. Date of Electronic Publication: 2025 Jun 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8003761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0909 (Electronic) Linking ISSN: 01410229 NLM ISO Abbreviation: Enzyme Microb Technol Subsets: MEDLINE

MeSH Terms: Skin Aging*/drug effects , Skin Aging*/radiation effects , Collagen*/biosynthesis , Matrix Metalloproteinases*/metabolism , Matrix Metalloproteinases*/genetics, Humans ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Keratinocytes/radiation effects ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/radiation effects ; Ultraviolet Rays ; Cellular Senescence/drug effects ; Oxidative Stress/drug effects ; Cell Line ; HaCaT Cells ; Matrix Metalloproteinase 1/metabolism ; Matrix Metalloproteinase 1/genetics ; Skin/drug effects ; Signal Transduction/drug effects

Xanthohumol suppresses ECM degradation in osteoarthritis through the Nrf2/ PERK/ATF4/C/EBPβ signaling pathway.

Authors: Zheng T Niu S Zhou Q et al.

Source: Cellular and molecular biology (Noisy-le-Grand, France) [Cell Mol Biol (Noisy-le-grand)] 2025 Dec 06; Vol. 71 (11), pp. 20-30. Date of Electronic Publication: 2025 Dec 06.

Publication Type: Journal Article

Journal Info: Publisher: C.M.B. Association Country of Publication: France NLM ID: 9216789 Publication Model: Electronic Cited Medium: Internet ISSN: 1165-158X (Electronic) Linking ISSN: 01455680 NLM ISO Abbreviation: Cell Mol Biol (Noisy-le-grand) Subsets: MEDLINE

MeSH Terms: Propiophenones*/pharmacology , Propiophenones*/therapeutic use , Osteoarthritis*/drug therapy , Osteoarthritis*/metabolism , Osteoarthritis*/pathology , Flavonoids*/pharmacology , Flavonoids*/therapeutic use , Signal Transduction*/drug effects , Extracellular Matrix*/metabolism , Extracellular Matrix*/drug effects, Animals ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/genetics ; Chondrocytes/drug effects ; Chondrocytes/metabolism ; Rats ; Activating Transcription Factor 4/metabolism ; eIF-2 Kinase/metabolism ; CCAAT-Enhancer-Binding Protein-beta/metabolism ; Male ; Matrix Metalloproteinase 13/metabolism ; Matrix Metalloproteinase 13/genetics ; Interleukin-1beta/pharmacology ; Collagen Type II/metabolism ; Collagen Type II/genetics ; Arthritis, Experimental/drug therapy ; Arthritis, Experimental/pathology

Chemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues.

Authors: Ling Z Niego B Li Q et al.

Source: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2025 Nov; Vol. 37 (47), pp. e05445. Date of Electronic Publication: 2025 Sep 06.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9885358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4095 (Electronic) Linking ISSN: 09359648 NLM ISO Abbreviation: Adv Mater Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/chemistry , Tissue Engineering*/methods , Neoplasms*/pathology , Neoplasms*/metabolism, Humans ; Cell Line, Tumor ; Tissue Scaffolds/chemistry ; Extracellular Matrix Proteins/metabolism ; Animals ; Glycosylation ; Proteomics

Degradation of perineuronal nets in hippocampal CA2 explains the loss of social cognition memory in Alzheimer's disease.

Authors: Chaunsali L Li J Fleischel E et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70813.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

MeSH Terms: Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Alzheimer Disease*/psychology , Alzheimer Disease*/genetics , CA2 Region, Hippocampal*/metabolism , CA2 Region, Hippocampal*/pathology , Extracellular Matrix*/metabolism , Social Behavior* , Memory Disorders*, Animals ; Mice ; Disease Models, Animal ; Mice, Transgenic ; Matrix Metalloproteinases/metabolism

M2 macrophage-derived Apolipoprotein E promotes fibroblast MMPs expression via LRP1-ERK signaling in chronic rhinosinusitis with nasal polyps.

Authors: Zhu Y Zhou J Tang R et al.

Source: Mucosal immunology [Mucosal Immunol] 2025 Oct; Vol. 18 (5), pp. 1171-1183. Date of Electronic Publication: 2025 Jul 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE

MeSH Terms: Nasal Polyps*/immunology , Nasal Polyps*/metabolism , Sinusitis*/immunology , Sinusitis*/metabolism , Low Density Lipoprotein Receptor-Related Protein-1*/metabolism , Macrophages*/immunology , Macrophages*/metabolism , Rhinitis*/immunology , Rhinitis*/metabolism , Apolipoproteins E*/metabolism , Apolipoproteins E*/genetics , Fibroblasts*/metabolism , Matrix Metalloproteinases*/metabolism, Humans ; Animals ; Mice ; Chronic Disease ; Male ; Female ; Mice, Knockout ; Disease Models, Animal ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase 9/genetics ; MAP Kinase Signaling System ; Cells, Cultured ; Adult ; Signal Transduction ; Middle Aged ; Rhinosinusitis

Extracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate.

Authors: Li YT; Department of Stem Cell Therapy Science, Graduate School of Medicine, The University of Osaka, Suita, Japan.

Source: ELife [Elife] 2025 Dec 04; Vol. 14. Date of Electronic Publication: 2025 Dec 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH Terms: Leukocytes*/physiology , Extracellular Matrix*/metabolism , Inflammation* , Transendothelial and Transepithelial Migration*, Humans ; Animals ; Extracellular Matrix Proteins/metabolism ; Basement Membrane

Decellularized matrix-hyaluronic acid-alginate hybrid hydrogels to enable a multi-layered full-thickness oral mucosa-on-a-chip.

Authors: Phan TV Pimpakan T Suwanchaikasem P et al.

Source: Journal of dentistry [J Dent] 2025 Dec; Vol. 163, pp. 106115. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE

MeSH Terms: Hydrogels*/chemistry , Alginates*/chemistry , Hyaluronic Acid*/chemistry , Mouth Mucosa*/cytology , Decellularized Extracellular Matrix*/chemistry , Tissue Engineering*/methods , Lab-On-A-Chip Devices*, Humans ; Animals ; Swine ; Human Umbilical Vein Endothelial Cells ; Keratinocytes/cytology ; Laminin ; Fibroblasts/cytology ; Cell Proliferation ; Tissue Scaffolds/chemistry ; Drug Combinations ; Collagen ; Proteoglycans ; Gingiva/cytology ; Extracellular Matrix/chemistry ; Cells, Cultured

In Vitro and In Silico Evaluation of a Novel Multifunctional Cyclic Peptide with Antioxidant, Tyrosinase-Inhibitory, and Extracellular Matrix-Modulating Activities.

Authors: Kim GH Kim BM

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 09; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 09.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Monophenol Monooxygenase*/antagonists & inhibitors , Monophenol Monooxygenase*/metabolism , Monophenol Monooxygenase*/chemistry , Antioxidants*/pharmacology , Antioxidants*/chemistry , Peptides, Cyclic*/pharmacology , Peptides, Cyclic*/chemistry , Peptides, Cyclic*/chemical synthesis , Extracellular Matrix*/drug effects , Extracellular Matrix*/metabolism , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry, Humans ; Molecular Docking Simulation ; Cell Survival/drug effects ; Matrix Metalloproteinase 1/metabolism

Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.

Authors: Hsieh CC Kuo HF Wang HH et al.

Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118604. Date of Electronic Publication: 2025 Sep 27.

Publication Type: Journal Article

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/metabolism , Vascular Remodeling*/drug effects , Naphthoquinones*/pharmacology , Naphthoquinones*/therapeutic use , Pulmonary Arterial Hypertension*/drug therapy , Pulmonary Arterial Hypertension*/physiopathology , Matrix Metalloproteinases*/metabolism , Tissue Inhibitor of Metalloproteinases*/metabolism, Animals ; Humans ; Male ; Mice ; Pulmonary Artery/drug effects ; Pulmonary Artery/pathology ; Pulmonary Artery/physiopathology ; Disease Models, Animal ; Bone Morphogenetic Protein Receptors, Type II/metabolism ; Bone Morphogenetic Protein Receptors, Type II/genetics ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Monocrotaline ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Tissue Inhibitor of Metalloproteinase-3/metabolism ; Cells, Cultured

Mechanical Stretch-Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin.

Authors: Sun Y Qian Q Xu L et al.

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Nov; Vol. 12 (41), pp. e11474. Date of Electronic Publication: 2025 Sep 17.

Publication Type: Journal Article

Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

MeSH Terms: Regeneration*/physiology , Matrix Metalloproteinase 2*/metabolism , Matrix Metalloproteinase 2*/genetics , Skin*/metabolism , Non-Fibrillar Collagens*/metabolism, Animals ; Mice ; Collagen Type XVII ; Humans ; Stress, Mechanical ; Extracellular Matrix/metabolism ; Stem Cells/metabolism

Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins.

Authors: Luthold C Didion M Rácz VS et al.

Source: EMBO reports [EMBO Rep] 2025 Nov; Vol. 26 (21), pp. 5270-5299. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH Terms: Melanocytes*/metabolism , Melanocytes*/cytology , Cell Differentiation* , Mechanotransduction, Cellular* , Extracellular Matrix Proteins*/metabolism, Microphthalmia-Associated Transcription Factor/metabolism ; Microphthalmia-Associated Transcription Factor/genetics ; Animals ; Mice ; Focal Adhesion Kinase 1/metabolism ; Humans ; Fibronectins/metabolism ; Extracellular Matrix/metabolism ; MAP Kinase Signaling System ; Signal Transduction ; Cell Proliferation ; Cell Movement ; Extracellular Signal-Regulated MAP Kinases/metabolism