Suchergebnisse - "MASS-SPECTROMETRY"

Host cell protein quantitation by LC-MS. Experimental demonstration, qualification, and comparison of methods in USP 1132.1.

Autoren: Chrone VG Blaszczyk AJ Zhang DH et al.

Quelle: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Nov 15; Vol. 265, pp. 117051. Date of Electronic Publication: 2025 Jul 03.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH-Schlagworte: Drug Contamination*/prevention & control , Mass Spectrometry*/methods , Proteins*/analysis , Biological Products*/analysis, Animals ; Cricetulus ; CHO Cells ; Chromatography, Liquid/methods ; Antibodies, Monoclonal/analysis ; Antibodies, Monoclonal/chemistry ; Reproducibility of Results ; Pharmacopoeias as Topic ; Tandem Mass Spectrometry/methods ; Cricetinae ; Enzyme-Linked Immunosorbent Assay/methods ; Liquid Chromatography-Mass Spectrometry

Open-Source System Suitability: Mass Spectrometry Query Language Lab (MassQLab).

Autoren: Winter HL Johnson D Jarmusch AK

Quelle: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2025 Dec 15; Vol. 39 (23), pp. e10132.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN: 1097-0231 (Electronic) Linking ISSN: 09514198 NLM ISO Abbreviation: Rapid Commun Mass Spectrom Subsets: MEDLINE

MeSH-Schlagworte: Software* , Mass Spectrometry*/methods , Mass Spectrometry*/instrumentation, Tandem Mass Spectrometry/methods ; Metabolomics/methods ; Chromatography, Liquid

Forensic detection and quantification of methomyl in animal stomach contents using liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) and liquid Chromatography tandem mass spectrometry (LC-MS/MS) in Japan.

Autoren: Yohannes YB Tanaka A Kihara Y et al.

Quelle: The Journal of veterinary medical science [J Vet Med Sci] 2025 Dec 03; Vol. 87 (12), pp. 1494-1498. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Japanese Society Of Veterinary Science Country of Publication: Japan NLM ID: 9105360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-7439 (Electronic) Linking ISSN: 09167250 NLM ISO Abbreviation: J Vet Med Sci Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/veterinary , Tandem Mass Spectrometry*/methods , Gastrointestinal Contents*/chemistry , Methomyl*/analysis , Methomyl*/poisoning, Animals ; Japan ; Dogs ; Chromatography, Liquid/veterinary ; Chromatography, Liquid/methods ; Cats ; Male ; Female ; Liquid Chromatography-Mass Spectrometry

Simultaneous multiple determination of pesticide residues in pistachios utilizing a QuEChERS-based method combined with UPLC-MS/MS, GC-MS/MS, and Monte Carlo simulation for health risk assessment.

Autoren: Ebrahimi-Najafabadi H Tezerji NS Rezaei R et al.

Quelle: Food chemistry [Food Chem] 2025 Dec 01; Vol. 494, pp. 146114. Date of Electronic Publication: 2025 Sep 03.

Publikationsart: Journal Article; Evaluation Study

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Pesticide Residues*/analysis , Pesticide Residues*/isolation & purification , Pesticide Residues*/chemistry , Tandem Mass Spectrometry*/methods , Food Contamination*/analysis , Gas Chromatography-Mass Spectrometry*/methods , Pistacia*/chemistry, Risk Assessment ; Chromatography, High Pressure Liquid/methods ; Monte Carlo Method ; Humans ; Limit of Detection ; Liquid Chromatography-Mass Spectrometry

Molecular characterization of natural organic matter using complementary liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry techniques.

Autoren: Hamzah LS Choi MJ Baik S et al.

Quelle: Journal of chromatography. A [J Chromatogr A] 2025 Nov 22; Vol. 1763, pp. 466426. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE

MeSH-Schlagworte: Humic Substances*/analysis , Gas Chromatography-Mass Spectrometry*/methods , Organic Chemicals*/analysis , Organic Chemicals*/chemistry , Mass Spectrometry*/methods, Chromatography, Liquid/methods ; Rivers/chemistry ; Solid Phase Extraction ; Benzopyrans/analysis ; Benzopyrans/chemistry ; Molecular Weight ; Liquid Chromatography-Mass Spectrometry

Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS.

Autoren: Wu V Moyal A Othman A et al.

Quelle: The Analyst [Analyst] 2025 Nov 17; Vol. 150 (23), pp. 5201-5211. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 0372652 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-5528 (Electronic) Linking ISSN: 00032654 NLM ISO Abbreviation: Analyst Subsets: MEDLINE

MeSH-Schlagworte: Phospholipids*/chemistry , Phospholipids*/analysis , Phospholipids*/blood , Electrons* , Glycerides*/chemistry , Glycerides*/analysis , Glycerides*/blood , Mass Spectrometry*/methods, Chromatography, Liquid/methods ; Animals ; Tandem Mass Spectrometry/methods ; Liver/chemistry ; Liquid Chromatography-Mass Spectrometry

Residue depletion study and withdrawal period in milk for intramuscular gentamicin in dairy cows using LC-MS/MS.

Autoren: Kim D Nam SM Moon H et al.

Quelle: Journal of veterinary science [J Vet Sci] 2025 Nov; Vol. 26 (6), pp. e89.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Korean Society of Veterinary Science Country of Publication: Korea (South) NLM ID: 100964185 Publication Model: Print Cited Medium: Internet ISSN: 1976-555X (Electronic) Linking ISSN: 1229845X NLM ISO Abbreviation: J Vet Sci Subsets: MEDLINE

MeSH-Schlagworte: Milk*/chemistry , Tandem Mass Spectrometry*/veterinary , Tandem Mass Spectrometry*/methods , Gentamicins*/administration & dosage , Gentamicins*/analysis , Gentamicins*/chemistry , Drug Residues*/analysis , Anti-Bacterial Agents*/analysis , Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/chemistry, Animals ; Cattle ; Female ; Chromatography, Liquid/veterinary ; Chromatography, Liquid/methods ; Injections, Intramuscular/veterinary ; Liquid Chromatography-Mass Spectrometry

Utilizing liquid chromatography-mass spectrometry to map targeting of snake venom components by antivenom.

Autoren: Kumar R Kumar S Rathore AS

Quelle: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Nov 01; Vol. 1265, pp. 124768. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Antivenins*/chemistry , Antivenins*/pharmacology , Snake Venoms*/chemistry , Snake Venoms*/analysis , Chromatography, Reverse-Phase*/methods , Mass Spectrometry*/methods, Animals ; Tandem Mass Spectrometry/methods ; Chromatography, Liquid/methods ; Mice ; Liquid Chromatography-Mass Spectrometry

Detection of Pesticide Residues in Fruits and Vegetables Involving Different Chromatographic Techniques (LC-MS/MS, GC-MS/MS, GC and HPLC).

Autoren: Jan I Rashied F Malik NA et al.

Quelle: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Nov; Vol. 39 (11), pp. e70224.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH-Schlagworte: Pesticide Residues*/analysis , Vegetables*/chemistry , Fruit*/chemistry , Tandem Mass Spectrometry*/methods , Gas Chromatography-Mass Spectrometry*/methods, Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid/methods ; Food Contamination/analysis ; Chromatography, Gas/methods ; Liquid Chromatography-Mass Spectrometry

Comprehensive Metabolic Profiling of Resigratinib, a Novel FGFR Inhibitor, Using Integrated LC-MS/MS and LC-Orbitrap-HRMS.

Autoren: An X Mao Y Fan A et al.

Quelle: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2025 Dec 30; Vol. 39 (24), pp. e10141.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN: 1097-0231 (Electronic) Linking ISSN: 09514198 NLM ISO Abbreviation: Rapid Commun Mass Spectrom Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods , Receptors, Fibroblast Growth Factor*/antagonists & inhibitors, Animals ; Dogs ; Microsomes, Liver/metabolism ; Microsomes, Liver/chemistry ; Humans ; Rats ; Chromatography, Liquid/methods ; Rats, Sprague-Dawley ; Male ; Macaca fascicularis ; Haplorhini ; Metabolome ; Liquid Chromatography-Mass Spectrometry

Development, validation and clinical implementation of a HPLC-MS/MS method for the simultaneous quantification of bictegravir, emtricitabine, doravirine, cabotegravir, lenacapavir, fostemsavir, tenofovir alafenamide and the corresponding metabolites temsavir and tenofovir, in human plasma.

Autoren: Mattino A Ferrari D Nozza S et al.

Quelle: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Dec 15; Vol. 1267, pp. 124803. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods, Humans ; Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Limit of Detection ; Linear Models ; Tenofovir/blood ; Tenofovir/analogs & derivatives ; Pyridones/blood ; Emtricitabine/blood ; Heterocyclic Compounds, 4 or More Rings/blood ; Male ; Adenine/blood ; Adenine/analogs & derivatives ; Alanine ; Drug Monitoring ; Liquid Chromatography-Mass Spectrometry ; Heterocyclic Compounds, 3-Ring ; Piperazines ; Indazoles ; Acetamides ; Amides

First report of borbotoxin occurrence in Brazilian Prorocentrum borbonicum isolates: LC-MS/MS detection and preliminary structural insights.

Autoren: Kleemann CR Hoff RB Schramm MA et al.

Quelle: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Dec 15; Vol. 1267, pp. 124825. Date of Electronic Publication: 2025 Oct 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods , Marine Toxins*/chemistry , Marine Toxins*/analysis , Dinoflagellida*/chemistry , Oxocins*/analysis , Oxocins*/chemistry, Brazil ; Chromatography, Liquid/methods ; Liquid Chromatography-Mass Spectrometry

Targeted Metabolomic Methods for ¹³ C Stable Isotope Labeling with Uniformly Labeled Glucose and Glutamine Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Autoren: Jennings EQ Rathmell WK Rathmell JC

Quelle: Journal of proteome research [J Proteome Res] 2025 Dec 05; Vol. 24 (12), pp. 6328-6337. Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

MeSH-Schlagworte: Glutamine*/metabolism , Glutamine*/chemistry , Isotope Labeling*/methods , Tandem Mass Spectrometry*/methods , Glucose*/metabolism , Glucose*/chemistry , Metabolomics*/methods, Carbon Isotopes/chemistry ; Chromatography, Liquid/methods ; Citric Acid Cycle ; Glycolysis ; Humans ; Liquid Chromatography-Mass Spectrometry

MetScribeR: A Semiautomated Tool for Data Processing of In-House LC-MS Metabolite Reference Libraries.

Autoren: Tisch AM Inman JM Mathé EA et al.

Quelle: Journal of proteome research [J Proteome Res] 2025 Dec 05; Vol. 24 (12), pp. 6320-6327. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

MeSH-Schlagworte: Metabolomics*/methods , Software* , Tandem Mass Spectrometry*/methods, Chromatography, Liquid/methods ; Reference Standards ; Liquid Chromatography-Mass Spectrometry

Enhanced LC-MS Detection of γ-Aminobutyric Acid via Trimethylation Enhancement Using Diazomethane.

Autoren: Rosales CA Lepinsky NA Ramadan M et al.

Quelle: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2025 Dec 03; Vol. 36 (12), pp. 2699-2706. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

MeSH-Schlagworte: gamma-Aminobutyric Acid*/analysis , gamma-Aminobutyric Acid*/chemistry , Diazomethane*/chemistry , Mass Spectrometry*/methods, Animals ; Goldfish ; Retina/chemistry ; Chromatography, Liquid/methods ; Limit of Detection ; Methylation ; Reproducibility of Results ; Linear Models ; Liquid Chromatography-Mass Spectrometry

Development, qualification, and application of a highly efficient and robust new peak detection workflow for the LC-MS peptide mapping multi-attribute method.

Autoren: Pohl T Merkle PS Hudelmaier S et al.

Quelle: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2572411. Date of Electronic Publication: 2025 Oct 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

MeSH-Schlagworte: Peptide Mapping*/methods , Antibodies, Monoclonal*/chemistry , Antibodies, Monoclonal*/analysis , Mass Spectrometry*/methods , Peptides*/analysis , Peptides*/chemistry, Workflow ; Chromatography, Liquid/methods ; Humans ; Software ; Quality Control ; Liquid Chromatography-Mass Spectrometry

Simultaneous determination of 12 novel brominated flame retardants and their potential exposure via the dietary intake of processed foods in Korea.

Autoren: Shim M Lee JY Joung SK et al.

Quelle: Food chemistry [Food Chem] 2025 Dec 01; Vol. 494, pp. 142733. Date of Electronic Publication: 2025 Jan 07.

Publikationsart: Journal Article; Evaluation Study

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Flame Retardants*/analysis , Food Contamination*/analysis , Gas Chromatography-Mass Spectrometry*/methods , Dietary Exposure*/analysis , Fast Foods*/analysis, Republic of Korea ; Humans ; Tandem Mass Spectrometry/methods ; Food, Processed

A novel application of LC-MS/MS accurately quantifies the labile redox pools of cellular coenzymes Q 9 and Q 10 .

Autoren: Jain A Li VW Salem J et al.

Quelle: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 01; Vol. 240, pp. 96-107. Date of Electronic Publication: 2025 Aug 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

MeSH-Schlagworte: Ubiquinone*/analogs & derivatives , Ubiquinone*/metabolism , Ubiquinone*/analysis , Tandem Mass Spectrometry*/methods, Animals ; Oxidation-Reduction ; Mice ; Humans ; Chromatography, Liquid/methods ; Mitochondria/metabolism ; Macrophages/metabolism ; Macrophages/drug effects ; Liquid Chromatography-Mass Spectrometry

Aptamer-functionalized magnetic covalent organic frameworks for rapid extraction and LC-MS/MS quantification of gentamicin in milk.

Autoren: Liu H Cao H Xiang Y et al.

Quelle: Food chemistry [Food Chem] 2025 Nov 30; Vol. 493 (Pt 3), pp. 145889. Date of Electronic Publication: 2025 Aug 10.

Publikationsart: Journal Article; Evaluation Study

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Milk*/chemistry , Tandem Mass Spectrometry*/methods , Solid Phase Extraction*/methods , Solid Phase Extraction*/instrumentation , Gentamicins*/isolation & purification , Gentamicins*/chemistry , Gentamicins*/analysis , Anti-Bacterial Agents*/isolation & purification , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/analysis , Metal-Organic Frameworks*/chemistry , Aptamers, Nucleotide*/chemistry , Drug Residues*/isolation & purification , Drug Residues*/chemistry, Animals ; Food Contamination/analysis ; Cattle ; Adsorption ; Chromatography, Liquid/methods ; Limit of Detection ; Chromatography, High Pressure Liquid/methods ; Liquid Chromatography-Mass Spectrometry

A Novel and Validated GC-MS/MS Method for the Detection of Four Opioids and Seven Fentanoids in Oral Fluid for Forensic Applications.

Autoren: Tittarelli R Filardi D Mineo F et al.

Quelle: Molecules (Basel, Switzerland) [Molecules] 2025 Nov 20; Vol. 30 (22). Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MeSH-Schlagworte: Gas Chromatography-Mass Spectrometry*/methods , Analgesics, Opioid*/analysis , Saliva*/chemistry , Fentanyl*/analogs & derivatives , Fentanyl*/analysis , Substance Abuse Detection*/methods , Forensic Toxicology*/methods, Humans ; Tandem Mass Spectrometry/methods ; Solid Phase Extraction ; Limit of Detection ; Reproducibility of Results