Suchergebnisse - "MAPS"

The relationship between interfacial overlap and functional divergence in the yeast protein-protein interaction network.

Autoren: Han Y Ghadie M Xia Y

Quelle: Structure (London, England : 1993) [Structure] 2025 Dec 04; Vol. 33 (12), pp. 2164-2176.e2. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

MeSH-Schlagworte: Protein Interaction Maps* , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/genetics, Protein Binding ; Protein Interaction Mapping ; Models, Molecular

Optimisation of floor evacuation map based on drive design.

Autoren: Liao H Zheng K Yi J

Quelle: Ergonomics [Ergonomics] 2025 Dec; Vol. 68 (12), pp. 1953-1966. Date of Electronic Publication: 2024 Dec 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0373220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5847 (Electronic) Linking ISSN: 00140139 NLM ISO Abbreviation: Ergonomics Subsets: MEDLINE

MeSH-Schlagworte: Maps as Topic*, Humans ; Male ; Female ; Young Adult ; Adult ; Reaction Time ; Memory, Short-Term

Metabolic enzyme-associated protein-protein interactions (mPPIs) in cancer: potential vulnerability for cancer treatment?

Autoren: Tang YT Chen TY Liu ZY et al.

Quelle: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2025 Dec; Vol. 46 (12), pp. 3154-3162. Date of Electronic Publication: 2025 Jun 20.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

MeSH-Schlagworte: Neoplasms*/metabolism , Neoplasms*/drug therapy , Neoplasms*/pathology , Neoplasms*/enzymology , Protein Interaction Maps*, Humans ; Animals ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/pharmacology ; Drug Resistance, Neoplasm ; Glycolysis

Identification and validation of susceptibility modules and hub genes in polyarticular juvenile idiopathic arthritis using WGCNA and machine learning.

Autoren: Liu J Fan J Duan H et al.

Quelle: Autoimmunity [Autoimmunity] 2025 Dec; Vol. 58 (1), pp. 2437239. Date of Electronic Publication: 2024 Dec 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8900070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-842X (Electronic) Linking ISSN: 08916934 NLM ISO Abbreviation: Autoimmunity Subsets: MEDLINE

MeSH-Schlagworte: Arthritis, Juvenile*/genetics , Arthritis, Juvenile*/diagnosis , Machine Learning* , Gene Regulatory Networks* , Protein Interaction Maps*/genetics , Gene Expression Profiling* , Computational Biology*/methods, Humans ; Genetic Predisposition to Disease ; Biomarkers ; Transcriptome ; Prognosis ; Child ; Databases, Genetic ; Gene Ontology

Genome-Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms-Fish Hosts System and Drug Target Identification.

Autoren: Zhang D Zhao JM Xiang CY et al.

Quelle: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Dec; Vol. 12 (45), pp. e14618. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

MeSH-Schlagworte: Platyhelminths*/genetics , Platyhelminths*/metabolism , Host-Parasite Interactions*/genetics , Goldfish*/parasitology , Goldfish*/genetics , Protein Interaction Maps*/genetics, Animals ; Genome, Helminth/genetics ; Fish Diseases/parasitology ; Helminth Proteins/genetics ; Helminth Proteins/metabolism

Neurons and neural networks to model proteins and protein networks.

Autoren: Samarasinghe S Minh-Thai TN Sorthiya K et al.

Quelle: Bio Systems [Biosystems] 2025 Dec; Vol. 258, pp. 105613. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 0430773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8324 (Electronic) Linking ISSN: 03032647 NLM ISO Abbreviation: Biosystems Subsets: MEDLINE

MeSH-Schlagworte: Neural Networks, Computer* , Neurons*/physiology , Neurons*/metabolism , Proteins*/metabolism , Models, Biological* , Protein Interaction Maps*/physiology, Animals ; Humans

Proteomic Analysis of Serum Samples in Ovulatory Polycystic Ovary Syndrome and Construction of a Protein Interaction Pathway.

Autoren: Fazilat A Majidzadeh-A K Gilany K et al.

Quelle: The protein journal [Protein J] 2025 Dec; Vol. 44 (6), pp. 773-788. Date of Electronic Publication: 2025 Oct 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Netherlands NLM ID: 101212092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8355 (Electronic) Linking ISSN: 15723887 NLM ISO Abbreviation: Protein J Subsets: MEDLINE

MeSH-Schlagworte: Polycystic Ovary Syndrome*/blood , Proteomics*/methods , Protein Interaction Maps* , Ovulation*/blood , Blood Proteins*/metabolism , Proteome*/metabolism, Female ; Humans ; Adult

A High Modulus, Multi-Stimuli Responsive, Interwoven Protein Network With Topologically Confined Micro-Association.

Autoren: Xu T Sun Y Wang YX et al.

Quelle: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2025 Nov 24; Vol. 64 (48), pp. e202516010. Date of Electronic Publication: 2025 Oct 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

MeSH-Schlagworte: Protein Interaction Maps*, Calmodulin/chemistry ; Calmodulin/metabolism

Meta-Analysis and Topological Perturbation in Interactomic Network for Antiopioid Addiction Drug Repurposing.

Autoren: Zhang C Cottrell S Jones B et al.

Quelle: Journal of chemical information and modeling [J Chem Inf Model] 2025 Nov 24; Vol. 65 (22), pp. 12313-12330. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article; Meta-Analysis

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

MeSH-Schlagworte: Drug Repositioning* , Opioid-Related Disorders*/drug therapy , Opioid-Related Disorders*/genetics , Opioid-Related Disorders*/metabolism , Protein Interaction Maps*/drug effects, Humans

Network centric identification of PI3K/Akt hub proteins as key oncogenic drivers and therapeutic targets.

Autoren: Fadhal E; Department of Mathematics & Statistics, College of Science, King Faisal University, P. O. Box 400, Al-Ahsa, 31982, Saudi Arabia. efadhal@kfu.edu.sa.

Quelle: Scientific reports [Sci Rep] 2025 Nov 19; Vol. 15 (1), pp. 40714. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Phosphatidylinositol 3-Kinases*/metabolism , Phosphatidylinositol 3-Kinases*/genetics , Protein Interaction Maps* , Neoplasms*/metabolism , Neoplasms*/genetics , Neoplasms*/drug therapy , Oncogenes*, Humans ; Signal Transduction ; Molecular Targeted Therapy

PPI-based screening of hub genes related to sepsis migration/pyroptosis and immune infiltration analysis.

Autoren: Ma X Wang J Han K et al.

Quelle: PloS one [PLoS One] 2025 Nov 18; Vol. 20 (11), pp. e0336982. Date of Electronic Publication: 2025 Nov 18 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Sepsis*/genetics , Sepsis*/immunology , Sepsis*/pathology , Pyroptosis*/genetics , Protein Interaction Maps*/genetics, Humans ; Gene Regulatory Networks ; MicroRNAs/genetics ; Cell Movement/genetics ; Gene Expression Profiling ; RNA, Messenger/genetics ; Databases, Genetic ; Gene Expression Regulation

A Protein Interactome-Based Framework Reveals the General Toxicity of Chemicals.

Autoren: Gan X Li G Yang W et al.

Quelle: Environmental science & technology [Environ Sci Technol] 2025 Nov 18; Vol. 59 (45), pp. 24291-24301. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE

MeSH-Schlagworte: Protein Interaction Maps*, Animals ; Zebrafish ; Humans ; Toxicogenetics ; Fungicides, Industrial/toxicity ; COVID-19

Comparative Analysis of Host-Pathogen Protein-Protein Interactions between Human and Various Strains of Mycobacterium Tuberculosis.

Autoren: Verma D Mudgal B Tufchi N et al.

Quelle: Clinical laboratory [Clin Lab] 2025 Nov 01; Vol. 71 (11).

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Clinical Laboratory Publications Country of Publication: Germany NLM ID: 9705611 Publication Model: Print Cited Medium: Internet ISSN: 1433-6510 (Print) Linking ISSN: 14336510 NLM ISO Abbreviation: Clin Lab Subsets: MEDLINE

MeSH-Schlagworte: Mycobacterium tuberculosis*/pathogenicity , Mycobacterium tuberculosis*/metabolism , Host-Pathogen Interactions* , Bacterial Proteins*/metabolism , Tuberculosis*/microbiology , Tuberculosis*/metabolism , Protein Interaction Maps*, Humans ; Protein Interaction Mapping/methods

Dysregulation of huntingtin interacting protein networks in human juvenile Huntington's disease brain.

Autoren: Podvin S Rosenthal B Mosier C et al.

Quelle: Journal of Huntington's disease [J Huntingtons Dis] 2025 Nov; Vol. 14 (4), pp. 354-368. Date of Electronic Publication: 2025 Jul 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101589965 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-6400 (Electronic) Linking ISSN: 18796397 NLM ISO Abbreviation: J Huntingtons Dis Subsets: MEDLINE

MeSH-Schlagworte: Huntington Disease*/metabolism , Huntington Disease*/genetics , Huntingtin Protein*/metabolism , Huntingtin Protein*/genetics , Cerebral Cortex*/metabolism , Putamen*/metabolism , Protein Interaction Maps* , Brain*/metabolism, Humans ; Adolescent ; Child ; Proteomics ; Male ; Female

Integrative Investigation of Flavonoids Targeting YBX1 Protein-Protein Interaction Network in Breast Cancer: From Computational Analysis to Experimental Validation.

Autoren: Sreelekshmi PK Pooja SK Vidya N et al.

Quelle: Molecular biotechnology [Mol Biotechnol] 2025 Nov; Vol. 67 (11), pp. 4212-4232. Date of Electronic Publication: 2024 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 9423533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0305 (Electronic) Linking ISSN: 10736085 NLM ISO Abbreviation: Mol Biotechnol Subsets: MEDLINE

MeSH-Schlagworte: Y-Box-Binding Protein 1*/metabolism , Y-Box-Binding Protein 1*/chemistry , Y-Box-Binding Protein 1*/genetics , Breast Neoplasms*/metabolism , Breast Neoplasms*/drug therapy , Flavonoids*/pharmacology , Flavonoids*/chemistry , Protein Interaction Maps*/drug effects, Humans ; Female ; Molecular Docking Simulation ; Quercetin/pharmacology ; Quercetin/chemistry ; Flavonols ; MCF-7 Cells ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/drug effects ; Molecular Dynamics Simulation ; Protein Binding

Identifying candidate genes for spermatogenic failure and predicting ICSI outcomes using single-cell RNA sequencing and protein-protein interaction networks.

Autoren: Liu L Huang S Jiang F et al.

Quelle: Human reproduction (Oxford, England) [Hum Reprod] 2025 Nov 01; Vol. 40 (11), pp. 2066-2077.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 8701199 Publication Model: Print Cited Medium: Internet ISSN: 1460-2350 (Electronic) Linking ISSN: 02681161 NLM ISO Abbreviation: Hum Reprod Subsets: MEDLINE

MeSH-Schlagworte: Protein Interaction Maps*/genetics , Spermatogenesis*/genetics , Sperm Injections, Intracytoplasmic* , Infertility, Male*/genetics , Infertility, Male*/therapy, Humans ; Male ; Single-Cell Analysis/methods ; Machine Learning ; Sequence Analysis, RNA ; Transcriptome ; Adult

Conserved interfaces mediate multiple protein-protein interactions in a prokaryotic metabolon.

Autoren: Bhattacharyya S Ranganathan S Chowdhury S et al.

Quelle: Molecular systems biology [Mol Syst Biol] 2025 Nov; Vol. 21 (11), pp. 1490-1521. Date of Electronic Publication: 2025 Sep 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

MeSH-Schlagworte: Escherichia coli*/metabolism , Escherichia coli*/genetics , Escherichia coli Proteins*/metabolism , Escherichia coli Proteins*/chemistry , Escherichia coli Proteins*/genetics , Protein Interaction Maps*, Metabolic Networks and Pathways ; Protein Binding ; Folic Acid/biosynthesis ; Protein Interaction Mapping/methods ; Molecular Dynamics Simulation ; Purines

Multiscale proteomic modeling reveals protein networks driving Alzheimer's disease pathogenesis.

Autoren: Wang E Yu K Cao J et al.

Quelle: Cell [Cell] 2025 Oct 30; Vol. 188 (22), pp. 6186-6204.e13. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Alzheimer Disease*/genetics , Proteomics*/methods , Protein Interaction Maps*, Humans ; Induced Pluripotent Stem Cells/metabolism ; Neurons/metabolism ; Brain/metabolism ; Brain/pathology ; Neuroglia/metabolism

Relational subgraphs fused with complete subgraphs based on the knowledge graph for mining protein complexes.

Autoren: Zhao R Zhang D Kou Y et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 29; Vol. 15 (1), pp. 37767. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Data Mining*/methods , Arabidopsis*/metabolism , Arabidopsis*/genetics , Protein Interaction Mapping*/methods , Protein Interaction Maps* , Arabidopsis Proteins*/metabolism , Computational Biology*/methods, Databases, Protein

A comprehensive PDCoV-host proteome interaction map reveals potential antiviral targets.

Autoren: Yan W Wang K Liu S et al.

Quelle: PLoS pathogens [PLoS Pathog] 2025 Oct 24; Vol. 21 (10), pp. e1013615. Date of Electronic Publication: 2025 Oct 24 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

MeSH-Schlagworte: Proteome*/metabolism , Antiviral Agents*/pharmacology , Deltacoronavirus*/metabolism , Deltacoronavirus*/physiology , Deltacoronavirus*/drug effects , Host-Pathogen Interactions* , Coronavirus Infections*/metabolism , Coronavirus Infections*/virology , Coronavirus Infections*/drug therapy , Coronavirus Infections*/veterinary , Protein Interaction Maps* , Swine Diseases*/virology , Swine Diseases*/metabolism , Swine Diseases*/drug therapy, Animals ; Swine ; Virus Replication ; RNA-Binding Proteins/metabolism ; Humans