Výsledky vyhľadávania - "Lymphocytes/immunology"

Reprogramming CD8+ T-cell Branched N-Glycosylation Limits Exhaustion, Enhancing Cytotoxicity and Tumor Killing

Autori: Catarina M. Azevedo Bingxian Xie William G. Gunn a ďalší

Prispievatelia: Catarina M. Azevedo Bingxian Xie William G. Gunn a ďalší

Zdroj: Cancer Immunology Research. 13:1655-1673

Predmety: Colorectal Neoplasms/ immunology, Cytotoxicity, Immunologic, Colorectal Neoplasms/ therapy, Glycosylation, CD8-Positive T-Lymphocytes/ immunology, N-Acetylglucosaminyltransferases / metabolism, CD8-Positive T-Lymphocytes/ metabolism, Mice, Cell Line, Tumor, Polysaccharides / metabolism, Colorectal Neoplasms/ metabolism, Animals, Humans, Immunotherapy, Adoptive / methods, Colorectal Neoplasms/ pathology, N-Acetylglucosaminyltransferases / genetics

Popis súboru: application/pdf

Prístupová URL adresa: https://hdl.handle.net/10216/169503

Efficient generation of human immune system rats using human CD34+ cells

Autori: Ménoret, Séverine Renart-Depontieu, Florence Martin, Gaelle a ďalší

Prispievatelia: Ménoret, Séverine Renart-Depontieu, Florence Martin, Gaelle a ďalší

Zdroj: Stem Cell Reports

Predmety: MESH: Hematopoietic Stem Cells / cytology, MESH: T-Lymphocytes / immunology, MESH: Rats, [SDV]Life Sciences [q-bio], T-Lymphocytes, regenerative medicine, Antigens, CD34, MESH: Hematopoietic Stem Cells / immunology, Mice, Report, MESH: Receptors, Immunologic / metabolism, Animals, Humans, MESH: Animals, MESH: B-Lymphocytes / cytology, Immunologic / genetics, immunodeficient rodents, Receptors, Immunologic, MESH: Immune System / metabolism, cancer models, MESH: Mice, human immune system mice, B-Lymphocytes, MESH: Humans, MESH: Hematopoietic Stem Cells / metabolism, MESH: Cytokines / metabolism, Hematopoietic Stem Cell Transplantation, CD34/metabolism, Hematopoietic Stem Cells, Antigens, Differentiation, MESH: B-Lymphocytes / immunology, Rats, [SDV] Life Sciences [q-bio], MESH: B-Lymphocytes / metabolism, MESH: Hematopoietic Stem Cell Transplantation / methods, Differentiation, Immune System, Cytokines, MESH: Antigens, Immunologic / immunology, immunotherapy, MESH: T-Lymphocytes / metabolism, transplantation

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39151431
https://inserm.hal.science/inserm-04711780v1/document
https://doi.org/10.1016/j.stemcr.2024.07.005
https://inserm.hal.science/inserm-04711780v1

Circulating innate lymphoid cells are dysregulated in patients with prostate cancer

Autori: Maresca D. C. La Civita E. Romano B. a ďalší

Zdroj: Cell Mol Biol Lett
Cellular & Molecular Biology Letters, Vol 30, Iss 1, Pp 1-23 (2025)
Cellular & molecular biology letters, vol. 30, no. 1, pp. 48

Predmety: Prostatic Neoplasms / pathology, Lymphocytes / metabolism, Male, Innate lymphoid cells, Prostatic Neoplasms / immunology, 616.07, ILC2s, IL-13, IL-18, IL-33, ILC1s, Prostate cancer, Cell Line, Tumor, Humans, Prostatic Neoplasms/immunology, Prostatic Neoplasms/pathology, Prostatic Neoplasms/blood, Immunity, Innate, Lymphocytes/immunology, Lymphocytes/metabolism, Lymphocytes/pathology, Middle Aged, Cytokines/metabolism, Cytokines/blood, Aged, Leukocytes, Mononuclear/immunology, Lymphocytes, QH573-671, Prostatic Neoplasms / blood, Leukocytes, Mononuclear / immunology, Prostatic Neoplasms, Cytokines / blood, Cytokines / metabolism, Leukocytes, Mononuclear, Lymphocytes / pathology, Cytokines, Lymphocytes / immunology, Cytology, Research Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40247153
https://doaj.org/article/71b194f34d0b4f3d819b24c3a1ddabcd
https://hdl.handle.net/11588/1006455
https://archive-ouverte.unige.ch/unige:186016
https://doi.org/10.1186/s11658-025-00725-7
https://serval.unil.ch/resource/serval:BIB_C66FE4F0E846.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C66FE4F0E8468
https://serval.unil.ch/notice/serval:BIB_C66FE4F0E846

Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas

Autori: Chen, Jing Sobecki, Michal Krzywinska, Ewelina a ďalší

Prispievatelia: Chen, Jing Sobecki, Michal Krzywinska, Ewelina a ďalší

Zdroj: EMBO Mol Med
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3033-3056 (2024)

Predmety: Cancer-Associated Fibroblasts Immunology, Medicine (General), Adenocarcinoma Immunology, 10017 Institute of Anatomy, Cancer-Associated Fibroblasts Pathology, 10184 Institute of Veterinary Pathology, ADAM12 Protein Metabolism, Pancreatic Neoplasms Prevention & Control, ADAM12 Protein, 610 Medicine & health, QH426-470, CD8-Positive T-Lymphocytes, Adenocarcinoma, 10263 Institute of Experimental Immunology, Cancer Vaccines, Mice, CD8-Positive T-Lymphocytes Immunology, R5-920, Cancer-Associated Fibroblasts, Report, Carcinoma, Pancreatic Ductal Pathology, Genetics, Mice Inbred C57BL, Adenocarcinoma Pathology, Animals, Humans, Cancer Vaccines Immunology, Pancreatic Adenocarcinoma, Cancer Vaccines Administration & Dosage, Cancer-Associated Fibroblasts Metabolism, Disease Models Animal, Vaccination, Fibrosis, Pancreatic Neoplasms, Mice, Inbred C57BL, Disease Models, Animal, Pancreatic Neoplasms Immunology, 1313 Molecular Medicine, 11401 Comprehensive Cancer Center Zurich, Pancreatic Neoplasms Pathology, Carcinoma Pancreatic Ductal Therapy, Adenocarcinoma Therapy, 570 Life sciences, biology, Immunotherapy, Carcinoma Pancreatic Ductal Immunology, Carcinoma, Pancreatic Ductal

Popis súboru: application/pdf; chen_et_al_2024_fibrolytic_vaccination_against_adam12_reduces_desmoplasia_in_preclinical_pancreatic_adenocarcinomas.pdf - application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39478152
https://doaj.org/article/32a6bfacd9884de49c5ed19adffba64c
https://phaidra.vetmeduni.ac.at/o:3794
https://doi.org/10.1038/s44321-024-00157-4

ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells

Autori: Carretero-Iglesia, Laura Hall, Olivia J Berret, Jérémy a ďalší

Prispievatelia: Carretero-Iglesia, Laura Hall, Olivia J Berret, Jérémy a ďalší

Zdroj: Nat Cancer

Predmety: Cytotoxicity, Immunologic, ADP-ribosyl Cyclase 1 / immunology, T-Lymphocytes, Tumor Escape / drug effects, [SDV.CAN]Life Sciences [q-bio]/Cancer, Multiple Myeloma / immunology, Lymphocyte Activation / drug effects, Multiple Myeloma / drug therapy, 616.07, Lymphocyte Activation, Article, Mice, Cytotoxicity, Immunologic / drug effects, Antigens, Neoplasm, Cell Line, Tumor, T-Lymphocytes / drug effects, Animals, Humans, Tumor Escape / immunology, B-Cell Maturation Antigen, Clinical Trials as Topic, Lymphocyte Activation / immunology, T-Lymphocytes / immunology, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, ADP-ribosyl Cyclase 1, Xenograft Model Antitumor Assays, Antigens, Neoplasm / immunology, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, Immunotherapy / methods, Tumor Escape, Immunotherapy, B-Cell Maturation Antigen / immunology, Multiple Myeloma

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39261676
https://ora.ox.ac.uk/objects/uuid:c3622b6e-528d-4447-a487-c45f54ddb9e6
https://doi.org/10.1038/s43018-024-00821-1

Engineered CD4 TCR T cells with conserved high-affinity TCRs targeting NY-ESO-1 for advanced cellular therapies in cancer

Autori: Saillard, Margaux Cenerenti, Mara Reichenbach, Patrick a ďalší

Zdroj: Sci Adv
Science advances, vol. 11, no. 26, pp. eadu5754

Predmety: CD4-Positive T-Lymphocytes / metabolism, Antigens, Neoplasm / genetics, Melanoma / immunology, Cell- and Tissue-Based Therapy / methods, Receptors, Antigen, T-Cell / immunology, 616.07, Melanoma / therapy, Immunotherapy, Adoptive, Receptors, Antigen, T-Cell, alpha-beta / immunology, Mice, CD4-Positive T-Lymphocytes / immunology, Cell Line, Tumor, Humans, Animals, Receptors, Antigen, T-Cell / genetics, Membrane Proteins / genetics, Receptors, Antigen, T-Cell, alpha-beta / genetics, Neoplasms / therapy, Neoplasms / immunology, Membrane Proteins / immunology, Membrane Proteins / metabolism, Antigens, Neoplasm / immunology, Receptors, Antigen, T-Cell / metabolism, CD4-Positive T-Lymphocytes/immunology, CD4-Positive T-Lymphocytes/metabolism, Membrane Proteins/immunology, Membrane Proteins/genetics, Membrane Proteins/metabolism, Antigens, Neoplasm/immunology, Antigens, Neoplasm/genetics, Receptors, Antigen, T-Cell/genetics, Receptors, Antigen, T-Cell/metabolism, Receptors, Antigen, T-Cell/immunology, Melanoma/immunology, Melanoma/therapy, Receptors, Antigen, T-Cell, alpha-beta/genetics, Receptors, Antigen, T-Cell, alpha-beta/immunology, Neoplasms/therapy, Neoplasms/immunology, Cell- and Tissue-Based Therapy/methods, Biomedicine and Life Sciences

Popis súboru: application/pdf

Prístupová URL adresa: https://archive-ouverte.unige.ch/unige:186017
https://doi.org/10.1126/sciadv.adu5754
https://serval.unil.ch/notice/serval:BIB_339A47BC344E
https://serval.unil.ch/resource/serval:BIB_339A47BC344E.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_339A47BC344E8

Lack of junctional adhesion molecule (JAM)-B traps CD8 T cells in CNS border zones and ameliorates autoimmune neuroinflammation

Autori: Pareja, Javier Aydin, Sidar Zbinden, Mara a ďalší

Zdroj: Acta Neuropathol Commun
Acta Neuropathologica Communications, Vol 13, Iss 1, Pp 1-23 (2025)

Predmety: Blood-Brain Barrier / metabolism, Mice, Transgenic, 616.07, Cell Adhesion Molecules / deficiency, Mice, Neuroinflammatory Diseases / immunology, Neuroinflammation, Animals, Central Nervous System / metabolism, RC346-429, JAM-B, Mice, Knockout, Cell Adhesion Molecules / genetics, Glia limitans, Central Nervous System / pathology, Research, CD8-Positive T-Lymphocytes / metabolism, Encephalomyelitis, Autoimmune, Experimental / immunology, Encephalomyelitis, Autoimmune, Experimental / pathology, Mice, Inbred C57BL, CD8-Positive T-Lymphocytes / immunology, CD8 T cell, Neuroinflammatory Diseases / pathology, Blood-Brain Barrier / immunology, Neurology. Diseases of the nervous system, CNS, Cell Adhesion Molecules / metabolism, Central Nervous System / immunology, BBB, Neuroinflammatory Diseases / metabolism

Popis súboru: application/pdf

Prístupová URL adresa: https://doaj.org/article/9f98bd3d02944577b58744e110c745fa
https://archive-ouverte.unige.ch/unige:186856
https://doi.org/10.1186/s40478-025-02021-z

Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens

Autori: Di Liberto, Giovanni Egervari, Kristof Levente Vogrig, Alberto a ďalší

Zdroj: Acta Neuropathol
Acta neuropathologica 149(1), 35 (2025). doi:10.1007/s00401-025-02882-7
Acta neuropathologica, vol. 149, no. 1, pp. 35

Predmety: Male, CD8-Positive T-Lymphocytes, Autoantigens, Neurons / pathology, Neuroinflammation, pathology [Brain], pathology [Neurons], Encephalitis / metabolism, Humans, Encephalitis/pathology, Encephalitis/immunology, Encephalitis/metabolism, Female, Middle Aged, Neurons/pathology, Neurons/immunology, Neurons/metabolism, Hashimoto Disease/pathology, Hashimoto Disease/immunology, Adult, STAT1 Transcription Factor/metabolism, Synapses/pathology, Synapses/immunology, Synapses/metabolism, Aged, Autoantigens/immunology, Brain/pathology, Brain/immunology, CD8-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/pathology, Young Adult, Neurodegeneration, Phagocytes, Resident memory T cells, Synapses, pathology [Encephalitis], Neurons, Neurons / metabolism, Brain / immunology, Brain / pathology, Brain, CD8-Positive T-Lymphocytes / immunology, STAT1 Transcription Factor, Hashimoto Disease / pathology, metabolism [Neurons], STAT1 Transcription Factor / metabolism, Encephalitis, immunology [Brain], pathology [Synapses], immunology [Autoantigens], Encephalitis / immunology, Hashimoto Disease, 616.07, Autoantigens / immunology, Hashimoto Disease / immunology, pathology [Hashimoto Disease], Synapses / immunology, ddc:610, immunology [Encephalitis], immunology [Synapses], Original Paper, Synapses / pathology, immunology [CD8-Positive T-Lymphocytes], metabolism [Synapses], Neurons / immunology, Synapses / metabolism, Encephalitis / pathology, pathology [CD8-Positive T-Lymphocytes], immunology [Hashimoto Disease], CD8-Positive T-Lymphocytes / pathology, metabolism [STAT1 Transcription Factor], metabolism [Encephalitis], immunology [Neurons]

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40278930
https://pub.dzne.de/record/278073
https://serval.unil.ch/resource/serval:BIB_2BE75AE22CA6.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_2BE75AE22CA6
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_2BE75AE22CA66

Oligodendrocyte-derived IL-33 regulates self-reactive CD8+ T cells in CNS autoimmunity

Autori: Fonta, Nicolas Page, Nicolas Klimek, Bogna a ďalší

Zdroj: J Exp Med

Predmety: Central Nervous System, Encephalomyelitis, Autoimmune, Experimental, Oligodendroglia / immunology, Central Nervous System / pathology, Brief Definitive Report, Autoimmunity, Cell Differentiation, Encephalomyelitis, Autoimmune, Experimental / immunology, 616.07, CD8-Positive T-Lymphocytes, Interleukin-33, Cell Differentiation / immunology, Encephalomyelitis, Autoimmune, Experimental / pathology, Mice, Inbred C57BL, Oligodendroglia, Mice, CD8-Positive T-Lymphocytes / immunology, Interleukin-33 / genetics, Interleukin-33 / immunology, Oligodendroglia / metabolism, Interleukin-33 / metabolism, Animals, Autoimmunity / immunology, Central Nervous System / immunology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40227193

Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction

Autori: Osborn, Gabriel López-Abente, Jacobo Adams, Rebecca a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-20 (2025)
Osborn, G, López-Abente, J, Adams, R, Laddach, R, Grandits, M, Bax, H J, Chauhan, J, Pellizzari, G, Nakamura, M, Stavraka, C, Chenoweth, A, Palhares, L C G F, Evan, T, Lim, J H C, Gross, A, Moise, L, Jatiani, S, Figini, M, Bianchini, R, Jensen-Jarolim, E, Ghosh, S, Montes, A, Sayasneh, A, Kristeleit, R, Tsoka, S, Spicer, J, Josephs, D H & Karagiannis, S N 2025, ' Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction ', Nature Communications, vol. 16, no. 1, 2903 . https://doi.org/10.1038/s41467-025-57870-y, https://doi.org/10.1038/s41467-025-57870-y

Predmety: Receptors, IgE/metabolism, Science, Carcinoma, Ovarian Epithelial Drug Therapy, Ovarian Neoplasms Pathology, T-Lymphocytes, Regulatory/immunology, Macrophages/immunology, Carcinoma, Ovarian Epithelial, CD8-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes/immunology, T-Lymphocytes, Regulatory, Article, Carcinoma, Ovarian Epithelial Immunology, CD8-Positive T-Lymphocytes Immunology, Folate Receptor 1/immunology, Inflammation Immunology, Carcinoma, Ovarian Epithelial/immunology, Macrophages Drug Effects, Folate Receptor 1 Immunology, Humans, Folate Receptor 1, Ovarian Neoplasms Drug Therapy, Ovarian Neoplasms, Inflammation, Receptors, IgE, Macrophages, Receptors, IgE Metabolism, T-Lymphocytes, Regulatory Immunology, Macrophages Immunology, Inflammation/immunology, Immunoglobulin E, Middle Aged, Ovarian Neoplasms Immunology, Immunoglobulin E Immunology, Ovarian Neoplasms/immunology, Immunoglobulin E/immunology, Female, T-Lymphocytes, Regulatory Drug Effects

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40210642
https://doaj.org/article/26e18d7bcf7042dbbc220559f04677f5
https://kclpure.kcl.ac.uk/portal/en/publications/1797ddd9-2f9f-4b88-be79-aea7103f71af

AQP4-specific T cells determine lesion localization in the CNS in a model of NMOSD

Autori: Afzali, Ali Maisam Ulianov, Oleksii Eckardt, Luise a ďalší

Prispievatelia: Afzali, Ali Maisam Ulianov, Oleksii Eckardt, Luise a ďalší

Zdroj: Acta Neuropathol Commun
Acta Neuropathologica Communications, Vol 13, Iss 1, Pp 1-14 (2025)

Predmety: Central Nervous System, Spinal Cord / pathology, Aquaporin 4 / immunology, Encephalomyelitis, Autoimmune, Experimental, NMOSD, T-Lymphocytes, Neuromyelitis Optica / immunology, T cells, Mice, Transgenic, 616.07, B-Lymphocytes / immunology, Neuromyelitis Optica / pathology, Mice, Spinal Cord / immunology, Encephalomyelitis, Autoimmune, Experimental / metabolism, MOG, Animals, Central Nervous System / metabolism, RC346-429, Aquaporin 4, B-Lymphocytes, EAE, Central Nervous System / pathology, Research, T-Lymphocytes / immunology, Neuromyelitis Optica, Encephalomyelitis, Autoimmune, Experimental / immunology, B-Lymphocytes / metabolism, Encephalomyelitis, Autoimmune, Experimental / pathology, AQP4, ddc, Mice, Inbred C57BL, Disease Models, Animal, Spinal Cord, B-Lymphocytes / pathology, Female, Autoimmune astrocytopathy, Neurology. Diseases of the nervous system, Central Nervous System / immunology, T-Lymphocytes / metabolism, Spinal Cord / metabolism, T-Lymphocytes / pathology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39934927
https://doaj.org/article/0315276ce82a440298664f054fa178fe
https://archive-ouverte.unige.ch/unige:184345
https://doi.org/10.1186/s40478-025-01947-8
https://resolver.sub.uni-goettingen.de/purl?gro-2/151251
https://epub.ub.uni-muenchen.de/124628/
https://mediatum.ub.tum.de/1774098

B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4

Autori: Afzali, Ali Maisam Nirschl, Lucy Sie, Christopher a ďalší

Prispievatelia: Afzali, Ali Maisam Nirschl, Lucy Sie, Christopher a ďalší

Zdroj: Nature

Predmety: 0301 basic medicine, Aquaporin 4 / immunology, T-Lymphocytes, Neuromyelitis Optica / immunology, Receptors, Antigen, T-Cell, Thymus Gland / cytology, Aquaporin 4 / genetics, Receptors, Antigen, T-Cell / immunology, Thymus Gland, 616.07, Autoantigens / immunology, B-Lymphocytes / immunology, Autoantigens, CD40 Antigens / immunology, Article, Interleukin-21, Mice, 03 medical and health sciences, Neuromyelitis Optica / metabolism, Immune Tolerance, Animals, Humans, CD40 Antigens, Autoantibodies, Aquaporin 4, B-Lymphocytes, 0303 health sciences, Thyroid Epithelial Cells / metabolism, Autoantibodies / immunology, T-Lymphocytes / immunology, Neuromyelitis Optica, AIRE Protein, B-Lymphocytes / metabolism, Germinal Center, 3. Good health, Germinal Center / immunology, Aquaporin 4 / metabolism, Germinal Center / cytology, Thyroid Epithelial Cells, Thyroid Epithelial Cells / immunology, Aquaporin 4 / deficiency, Thymus Gland / immunology, Transcriptome

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38383779
https://archive-ouverte.unige.ch/unige:177648
https://doi.org/10.1038/s41586-024-07079-8
https://rdp.sfb274.de/literature/publications/162
https://resolver.sub.uni-goettingen.de/purl?gro-2/142433
https://epub.ub.uni-muenchen.de/117456/

Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses

Autori: Haskins, Breanne E Gullicksrud, Jodi A Wallbank, Bethan A a ďalší

Zdroj: Mucosal Immunol

Predmety: Protozoan Proteins, Cryptosporidiosis, Cryptosporidium, Epitopes, T-Lymphocyte, Antigens, Protozoan, Mice, Transgenic, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Article, Cryptosporidium / immunology, Mice, Interferon-gamma, Dendritic Cells / immunology, Animals, Humans, Intestinal Mucosa, Epitopes, T-Lymphocyte / immunology, Mice, Knockout, Protozoan Proteins / immunology, Lymphocyte Activation / immunology, Dendritic Cells, Antigens, Protozoan / immunology, Interferon-gamma / metabolism, 3. Good health, Mice, Inbred C57BL, Protozoan Proteins / metabolism, CD8-Positive T-Lymphocytes / immunology, Intestinal Mucosa / immunology, Cryptosporidiosis / immunology, Intestinal Mucosa / parasitology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38508522
https://archive-ouverte.unige.ch/unige:178790
https://doi.org/10.1016/j.mucimm.2024.03.003

The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1

Autori: Oikonomou, Vasileios Smith, Grace Constantine, Gregory a ďalší

Prispievatelia: Oikonomou, Vasileios Smith, Grace Constantine, Gregory a ďalší

Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
New England Journal of Medicine, vol 390, iss 20

Predmety: Male, 0301 basic medicine, MESH: AIRE Protein / genetics, [SDV]Life Sciences [q-bio], T-Lymphocytes, Pilot Projects, MESH: AIRE Protein / immunology, Pediatrics, Chemokine CXCL9, MESH: Pyrimidines / therapeutic use, Mice, MESH: Interferon-gamma / genetics, Endocrinology, MESH: Pyrazoles / pharmacology, MESH: Child, MESH: Animals, MESH: Janus Kinase Inhibitors / therapeutic use, Clinical Medicine General, Child, Polyendocrinopathies, Autoimmune, Mice, Knockout, 0303 health sciences, MESH: Middle Aged, Gastroenterology General, Gastroenterology, Inflammatory Disease, AIRE Protein, Genetics General, Middle Aged, [SDV] Life Sciences [q-bio], MESH: Transcription Factors / immunology, Pediatrics General, Female, Rheumatology General, Childhood Diseases, MESH: Interferon-gamma / immunology, Adult, MESH: T-Lymphocytes / immunology, MESH: Chemokine CXCL9 / genetics, MESH: Pyrazoles / therapeutic use, Adolescent, Knockout, Thyroid Disease, MESH: Autoantibodies / immunology, T-Cells, Dermatology, MESH: Transcription Factors / genetics, Autoimmune Disease, Dermatology General, MESH: Polyendocrinopathies, Allergy/Immunology General, Allergy/Immunology, MESH: AIRE Protein / deficiency, Interferon-gamma, 03 medical and health sciences, Adolescent Medicine, Rheumatology, Autoimmune / genetics, Outpatient-Based Clinical Medicine, Nitriles, Genetics, Animals, Humans, Janus Kinase Inhibitors, Adrenal Disease, MESH: Mice, MESH: Autoantibodies / blood, MESH: Nitriles / therapeutic use, Autoantibodies, MESH: Adolescent, MESH: Humans, Animal, Inflammatory Bowel Disease, Immunity, Autoimmune / immunology, MESH: Adult, Endocrinology General, MESH: Pilot Projects, MESH: Male, Disease Models, Animal, Pyrimidines, Polyendocrinopathies, Disease Models, Autoimmune / drug therapy, Pyrazoles, MESH: Disease Models, Clinical Medicine, MESH: Female, Autoimmune, Transcription Factors

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38810185
http://hdl.handle.net/10261/370632
https://api.elsevier.com/content/abstract/scopus_id/85194888497
https://inserm.hal.science/inserm-04676012v1
https://doi.org/10.1056/nejmoa2312665
https://inserm.hal.science/inserm-04676012v1/document
https://escholarship.org/content/qt6cw64500/qt6cw64500.pdf
https://escholarship.org/uc/item/6cw64500

IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells

Autori: Yang, Bin Piedfort, Ophélie Sanchez-Sanchez, Guillem a ďalší

Prispievatelia: Yang, Bin Piedfort, Ophélie Sanchez-Sanchez, Guillem a ďalší

Zdroj: Science Immunology. 10

Predmety: Knockout, Il4 protein, mouse, Sialic Acid Binding Ig-like Lectin 2, Immunology, Lymphocyte Activation/immunology, CD8-Positive T-Lymphocytes, Inbred C57BL, CD8-Positive T-Lymphocytes/immunology, Lymphocyte Activation, Sciences de la santé humaine, Immunologie & maladie infectieuse, CD8-Positive T-Lymphocytes -- immunology, Mice, Memory T Cells, Interleukin-4/immunology, Immunologie, Immunology and Allergy, Animals, Immunology & infectious disease, Human health sciences, Memory T Cells/immunology, Mice, Knockout, Sciences bio-médicales et agricoles, Sialic Acid Binding Ig-like Lectin 2 -- immunology, Lymphocyte Activation -- immunology, Sialic Acid Binding Ig-like Lectin 2/immunology, Mice, Inbred C57BL, Interleukin-4 -- immunology, Immunologic Memory -- immunology, Memory T Cells -- immunology, Immunologic Memory/immunology, Female, Interleukin-4, Immunologic Memory

Popis súboru: 2 full-text file(s): application/pdf; application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39919198

Brucella abortus impairs T lymphocyte responsiveness by mobilizing IL-1RA-secreting omental neutrophils

Autori: Joaquin M. Pellegrini Gabriela González-Espinoza Raheleh R. Shayan a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Predmety: Ly -- metabolism, Omentum -- immunology -- metabolism, Neutrophils, Science, T-Lymphocytes, Neutrophils -- immunology -- metabolism, Brucella abortus, CD8-Positive T-Lymphocytes, Inbred C57BL, Article, Brucellosis, B7-H1 Antigen, Monocytes, Mice, Animals, Humans, Antigens, Ly, Antigens, Immune Evasion, T-Lymphocytes -- immunology -- metabolism, Macrophages, Brucellosis -- immunology -- microbiology -- metabolism, Sciences bio-médicales et agricoles, Monocytes -- immunology -- metabolism, Macrophages -- immunology -- metabolism, Mice, Inbred C57BL, Interleukin 1 Receptor Antagonist Protein, B7-H1 Antigen -- metabolism -- genetics, Brucella abortus -- immunology, Female, Omentum

Popis súboru: 2 full-text file(s): application/pdf; application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39833171
https://doaj.org/article/8b32eea2b7ff42bcaf3cbd9d17a63666

Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling

Autori: Bertrand, Lisa Nelde, Annika Ramirez, Bertha Cecilia a ďalší

Prispievatelia: Bertrand, Lisa Nelde, Annika Ramirez, Bertha Cecilia a ďalší

Zdroj: ISSN: 2041-1723.

Predmety: T cell, HIV - 1, Transalation, MHC, Ribosome profiling, Open reading frame, Alternative open reading frame, Antigen, MESH: Amino Acid Sequence, MESH: CD4-Positive T-Lymphocytes / immunology, MESH: Open Reading Frames* / genetics, MESH: Ribosome Profiling, MESH: Ribosomes* / metabolism, MESH: CD4-Positive T-Lymphocytes / virology, MESH: CD8-Positive T-Lymphocytes / immunology, MESH: Conserved Sequence, MESH: Genome, Viral, MESH: HIV Infections / immunology, MESH: HIV Infections / virology, MESH: HIV-1* / genetics, MESH: HIV-1* / immunology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases

Dostupnosť: https://hal.science/hal-04958976
https://hal.science/hal-04958976v1/document
https://hal.science/hal-04958976v1/file/41467_2025_Article_56773.pdf
https://doi.org/10.1038/s41467-025-56773-2

HIV-1 adapts to HLA class II-associated selection pressure exerted by CD4 + and CD8 + T cells

Autori: Alves, Eric Currenti, Jennifer Crawford, Keeley a ďalší

Predmety: CD4-Positive T-Lymphocytes - immunology, CD4-Positive T-Lymphocytes - metabolism, CD8-Positive T-Lymphocytes - immunology, CD8-Positive T-Lymphocytes - metabolism, Histocompatibility Antigens Class II - genetics, Histocompatibility Antigens Class II - immunology, Histocompatibility Antigens Class II - metabolism, HIV Infections - immunology, HIV Infections - virology, HIV-1 - immunology, Humans, Selection, Genetic

Popis súboru: pdf

Relation: ispartof: Science advances issue 7 vol 11; PMC11827868; WOS:001421952400023; 991005742485807891; https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12173367710007891/13173551780007891; alma:61MUN_INST/bibs/991005742485807891

Dostupnosť: https://doi.org/10.1126/sciadv.adr4238
https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/HIV-1-adapts-to-HLA-class-II-associated/991005742485807891
https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12173367710007891/13173551780007891

Dendritic cells as shepherds of T cell immunity in cancer

Autori: Pittet, Mikaël Di Pilato, Mauro Garris, Christopher a ďalší

Zdroj: Immunity. 56:2218-2230

Predmety: Neoplasms / therapy, Neoplasms / immunology, T-Lymphocytes, T-Lymphocytes / immunology, Cell Differentiation, Cell Communication, Dendritic Cells, 616.07, 3. Good health, Immunotherapy / methods, Neoplasms, Immune Tolerance, Dendritic Cells / immunology, Animals, Humans, Immunotherapy

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37708889
https://archive-ouverte.unige.ch/unige:182611
https://doi.org/10.1016/j.immuni.2023.08.014

Genomic investigations of unexplained acute hepatitis in children

Autori: Morfopoulou, S. Buddle, S. Torres Montaguth, O.E. a ďalší

Prispievatelia: Morfopoulou, S. Buddle, S. Torres Montaguth, O.E. a ďalší

Zdroj: Nature
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature, 617, 7961, pp. 564-573
Chikowore, P & Baillie, K 2023, ' Genomic investigations of unexplained acute hepatitis in children ', Nature, vol. 617, no. 7961, pp. 564-573 . https://doi.org/10.1038/s41586-023-06003-w

Predmety: Proteomics, T-Lymphocytes, B-Lymphocytes / immunology, Hepatitis, Radboudumc 6: Metabolic Disorders Human Genetics, Adenovirus Infections, Human, Liver/immunology, hepatitis, Child, B-Lymphocytes, Liver / virology, Adenovirus Infections, Human / epidemiology, Radboudumc 4: lnfectious Diseases and Global Health Paediatrics, RJ Pediatrics, Hepatitis/epidemiology, B-Lymphocytes/immunology, Genomics, Dependovirus, Adenovirus Infections, Human / immunology, Liver / immunology, Immunohistochemistry, 3. Good health, Radboudumc 6: Metabolic Disorders CMBI, Acute Disease / epidemiology, Liver, Acute Disease, RJ, CMBI - Radboud University Medical Center, QH426 Genetics, Radboudumc 4: lnfectious Diseases and Global Health Laboratory Medicine, Paediatric research, Article, Radboudumc 6: Metabolic Disorders Laboratory Medicine, SDG 3 - Good Health and Well-being, Humans, Clinical microbiology, QH426, Hepatitis / virology, MCC, Gene Expression Profiling, T-Lymphocytes / immunology, DAS, 500 Naturwissenschaften und Mathematik::570 Biowissenschaften, Biologie::570 Biowissenschaften, Biologie, T-Lymphocytes/immunology, Adenovirus Infections, Human/epidemiology, Laboratory Medicine - Radboud University Medical Center, Hepatitis / epidemiology, Acute Disease/epidemiology, Adenovirus Infections, Human / virology, Hepatitis / immunology

Popis súboru: application/pdf; text

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36996872
https://hdl.handle.net/20.500.12530/97194
https://hdl.handle.net/20.500.12530/95669
https://pure.amsterdamumc.nl/en/publications/15ad557f-23a9-4199-b809-2dd99323bbb3
https://doi.org/10.1038/s41586-023-06003-w
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https://hdl.handle.net/2066/294860
https://repository.ubn.ru.nl//bitstream/handle/2066/294860/294860.pdf
https://archive-ouverte.unige.ch/unige:180750
https://doi.org/10.1038/s41586-023-06003-w
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_44C4A127A8F61
http://europepmc.org/abstract/med/36996872
https://serval.unil.ch/resource/serval:BIB_44C4A127A8F6.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_44C4A127A8F6
https://pergamos.lib.uoa.gr/uoa/dl/object/3341297
https://hdl.handle.net/20.500.11820/459e9074-27a5-4169-87a8-146aa1eb5d01
https://www.pure.ed.ac.uk/ws/files/346013446/s41586_023_06003_w.pdf
https://refubium.fu-berlin.de/handle/fub188/41199
https://doi.org/10.1038/s41586-023-06003-w
https://doi.org/10.17169/refubium-40920
https://discovery-pp.ucl.ac.uk/id/eprint/10167781/
https://eprints.soton.ac.uk/481944/
https://hdl.handle.net/10023/27561