Search Results - "Lung Neoplasms/pathology"

First-Line Mobocertinib Versus Platinum-Based Chemotherapy in Patients With EGFR Exon 20 Insertion–Positive Metastatic Non–Small Cell Lung Cancer in the Phase III EXCLAIM-2 Trial

Authors: Pasi A. Jänne Bin-Chao Wang Byoung Chul Cho et al.

Source: J Clin Oncol
Journal of clinical oncology, vol. 43, no. 13, pp. 1553-1563

Subject Terms: Male, Adult, Aged, 80 and over, Lung Neoplasms, Aniline Compounds, Indoles, ORIGINAL REPORTS, Pemetrexed, Exons, Middle Aged, Progression-Free Survival, Carboplatin, ErbB Receptors, Pyrimidines, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Humans, Female, Aged, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Carboplatin/administration & dosage, Carboplatin/adverse effects, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/genetics, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/enzymology, Cisplatin/administration & dosage, Cisplatin/adverse effects, ErbB Receptors/genetics, ErbB Receptors/antagonists & inhibitors, Lung Neoplasms/drug therapy, Lung Neoplasms/genetics, Lung Neoplasms/pathology, Lung Neoplasms/enzymology, Pemetrexed/administration & dosage, Pemetrexed/adverse effects, Protein Kinase Inhibitors/therapeutic use, Protein Kinase Inhibitors/adverse effects, Cisplatin, Protein Kinase Inhibitors

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39879577
https://serval.unil.ch/notice/serval:BIB_F1541B0B9B82
https://serval.unil.ch/resource/serval:BIB_F1541B0B9B82.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F1541B0B9B821

Tumor-Infiltrating Clonal Hematopoiesis

Authors: Oriol Pich Elsa Bernard Maria Zagorulya et al.

Source: N Engl J Med
The New England journal of medicine, vol. 392, no. 16, pp. 1594-1608

Subject Terms: Male, Lung Neoplasms, Middle Aged, Article, Monocytes, Dioxygenases, DNA-Binding Proteins, Mice, Observational Studies as Topic, Cell Movement, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Mutation, Tumor Microenvironment, Animals, Humans, Female, Prospective Studies, Clonal Hematopoiesis, Neoplasm Recurrence, Local, Aged, Carcinoma, Non-Small-Cell Lung/genetics, Carcinoma, Non-Small-Cell Lung/immunology, Carcinoma, Non-Small-Cell Lung/mortality, Carcinoma, Non-Small-Cell Lung/pathology, Clonal Hematopoiesis/genetics, Clonal Hematopoiesis/immunology, Dioxygenases/genetics, DNA-Binding Proteins/genetics, Lung Neoplasms/genetics, Lung Neoplasms/mortality, Lung Neoplasms/pathology, Neoplasm Recurrence, Local/epidemiology, Neoplasm Recurrence, Local/genetics, Neoplasm Recurrence, Local/pathology, Tumor Microenvironment/immunology, Monocytes/immunology, Monocytes/pathology, Cell Movement/genetics, Cell Movement/immunology, Neoplasm Transplantation

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Access URL: https://pubmed.ncbi.nlm.nih.gov/40267425
https://ora.ox.ac.uk/objects/uuid:e20d5bce-3d87-4ac2-9e89-b887ca4cc72b
https://doi.org/10.1056/nejmoa2413361
https://serval.unil.ch/notice/serval:BIB_435B0ABCF518
https://serval.unil.ch/resource/serval:BIB_435B0ABCF518.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_435B0ABCF5187

Decoding the Clinical and Molecular Signatures of EGFR Common, Compound, and Uncommon Mutations in NSCLC: A Brief Report

Authors: Daniele Tavernari Maxime Borgeaud Ximeng Liu et al.

Source: Journal of thoracic oncology, vol. 20, no. 4, pp. 500-506

Subject Terms: Uncommon EGFR mutations, Male, Adult, Aged, 80 and over, Lung Neoplasms, Humans, Female, ErbB Receptors/genetics, Mutation, Lung Neoplasms/genetics, Lung Neoplasms/pathology, Lung Neoplasms/drug therapy, Carcinoma, Non-Small-Cell Lung/genetics, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/drug therapy, Middle Aged, Aged, Co-mutations, Compound EGFR mutations, EGFR, Non–small-cell lung cancer, ErbB Receptors, Carcinoma, Non-Small-Cell Lung

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39694414
https://archive-ouverte.unige.ch/unige:183984
https://doi.org/10.1016/j.jtho.2024.12.012
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_55E39726C98A3
https://serval.unil.ch/notice/serval:BIB_55E39726C98A
https://serval.unil.ch/resource/serval:BIB_55E39726C98A.P001/REF.pdf

Unforeseen nodal upstaging in patients undergoing segmentectomy without frozen section: a multicenter retrospective cohort study

Authors: Lin Huang Alessandro Brunelli Demetrios Stefanou et al.

Source: Surg Endosc
Surgical endoscopy, vol. 39, no. 4, pp. 2296-2303

Subject Terms: Humans, Retrospective Studies, Lung Neoplasms/surgery, Lung Neoplasms/pathology, Female, Male, Carcinoma, Non-Small-Cell Lung/surgery, Carcinoma, Non-Small-Cell Lung/pathology, Middle Aged, Aged, Pneumonectomy/methods, Neoplasm Staging, Frozen Sections, Lymphatic Metastasis, Lymph Nodes/pathology, Frozen section, Maximum standardized uptake values, Nodal upstaging, Non-small cell lung cancer, Segmentectomy, Article

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39948264
https://serval.unil.ch/notice/serval:BIB_A7DB1D9BC3A8
https://serval.unil.ch/resource/serval:BIB_A7DB1D9BC3A8.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A7DB1D9BC3A81

Long-Term Survival Outcomes With First-Line Nivolumab Plus Ipilimumab–Based Treatment in Patients With Metastatic NSCLC and Tumor Programmed Death-Ligand 1 Lower Than 1%: A Pooled Analysis

Authors: Peters, Solange Paz-Ares, Luis G. Reck, Martin et al.

Contributors: Peters, Solange Paz-Ares, Luis G. Reck, Martin et al.

Source: Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Journal of thoracic oncology, vol. 20, no. 1, pp. 94-108

Subject Terms: PD-L1, Nivolumab, Non–small cell lung cancer, Humans, Nivolumab/pharmacology, Nivolumab/therapeutic use, Nivolumab/administration & dosage, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/mortality, Lung Neoplasms/drug therapy, Lung Neoplasms/pathology, Lung Neoplasms/mortality, Lung Neoplasms/metabolism, Ipilimumab/pharmacology, Ipilimumab/therapeutic use, Ipilimumab/administration & dosage, Male, Female, Middle Aged, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, B7-H1 Antigen/metabolism, Aged, Adult, Survival Rate, Aged, 80 and over, Follow-Up Studies, Immunotherapy, Ipilimumab

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39369790
http://hdl.handle.net/10261/390933
https://api.elsevier.com/content/abstract/scopus_id/85208360083
https://serval.unil.ch/resource/serval:BIB_89D370D6F09D.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_89D370D6F09D
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Durvalumab With or Without Tremelimumab in Combination With Chemotherapy in First-Line Metastatic NSCLC: Five-Year Overall Survival Outcomes From the Phase 3 POSEIDON Trial

Authors: Peters, S. Cho, B.C. Luft, A.V. et al.

Source: Journal of thoracic oncology, vol. 20, no. 1, pp. 76-93

Subject Terms: Male, Adult, Humans, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/mortality, Lung Neoplasms/drug therapy, Lung Neoplasms/pathology, Lung Neoplasms/mortality, Antibodies, Monoclonal, Humanized/therapeutic use, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Antibodies, Monoclonal/therapeutic use, Female, Middle Aged, Aged, Survival Rate, Follow-Up Studies, Neoplasm Metastasis, Durvalumab, Five-year overall survival, Metastatic NSCLC, POSEIDON, Tremelimumab, Lung Neoplasms, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39243945
https://serval.unil.ch/resource/serval:BIB_9D803F1B2F65.P001/REF.pdf
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https://serval.unil.ch/notice/serval:BIB_9D803F1B2F65

Distal lung organoids derived from adult stem cells as novel tools in deciphering mechanisms of lung regeneration, infection, and cancer

Authors: Mark Bell Anna D Krasnodembskaya

Source: Bell, M & Krasnodembskaya, A D 2025, 'Distal lung organoids derived from adult stem cells as novel tools in deciphering mechanisms of lung regeneration, infection, and cancer', Stem cells translational medicine, vol. 14, no. 9. https://doi.org/10.1093/stcltm/szaf040

Subject Terms: SARS-CoV-2, COVID-19/pathology, Organoids/cytology, Humans, Regeneration, Lung/physiology, Lung Neoplasms/pathology, Animals, name=SDG 3 - Good Health and Well-being, Adult Stem Cells/cytology

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Access URL: https://pure.qub.ac.uk/en/publications/9ffbf52a-53c4-44bf-b7ee-04d7a38e9c48

TTF-1 negativity in synchronous M1b/M1c wildtype lung adenocarcinoma brain metastases predicts worse survival with increased risk of intracranial progression

Authors: Wasilewski, David Araceli, Tommaso Bischoff, Philip et al.

Source: J Neurooncol

Subject Terms: 0301 basic medicine, 03 medical and health sciences, 0302 clinical medicine, Research, Disease Progression [MeSH], Aged, 80 and over [MeSH], Aged [MeSH], TTF-1, Adenocarcinoma of Lung/surgery [MeSH], Survival, Male [MeSH], Brain Neoplasms/mortality [MeSH], Brain Metastasis, Ki67, Edema volume, LUAD, Female [MeSH], Lung Neoplasms/mortality [MeSH], Follow-Up Studies [MeSH], Brain Neoplasms/secondary [MeSH], Adult [MeSH], Humans [MeSH], Tumor volume, Retrospective Studies [MeSH], Middle Aged [MeSH], Adenocarcinoma of Lung/metabolism [MeSH], Survival Rate [MeSH], Biomarkers, Tumor/metabolism [MeSH], Adenocarcinoma of Lung/mortality [MeSH], Prognosis [MeSH], Lung Neoplasms/pathology [MeSH], Lung Neoplasms/metabolism [MeSH], Adenocarcinoma of Lung/pathology [MeSH], Brain Neoplasms/metabolism [MeSH], Thyroid Nuclear Factor 1/metabolism [MeSH]

Access URL: https://pubmed.ncbi.nlm.nih.gov/39630375
https://repository.publisso.de/resource/frl:6499899

Detection of genomic alterations in liquid biopsies from patients with non-small cell lung cancer using FoundationOne Liquid CDx: a cost-effectiveness analysis

Authors: Dolores Isla Rosa Álvarez María Arnal et al.

Source: Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Dipòsit Digital de la UB
instname
Docusalut
Conselleria de Salut i Consum del Govern de les Illes Balears

Subject Terms: Male, Lung Neoplasms, Biopsy, Cost-Benefit Analysis, España, Cost-Effectiveness Analysis, Carcinoma, Non-Small-Cell Lung* / pathology, Árboles de Decisión, Liquid Biopsy / methods, Lung Neoplasms* / genetics, Quality-Adjusted Life Years, Carcinoma, Non-Small-Cell Lung* / genetics, Modelos Econométricos, Clinical trials, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung* / drug therapy, Humans, Masculino, Análisis de Costo-Efectividad, Lung Neoplasms* / pathology, Decision Trees, Liquid Biopsy, High-Throughput Nucleotide Sequencing, High-Throughput Nucleotide Sequencing / methods, Lung Neoplasms* / drug therapy, Humanos, Spain, Años de Vida Ajustados por Calidad de Vida, Liquid Biopsy / economics, Càncer de pulmó, High-Throughput Nucleotide Sequencing / economics, Lung cancer, Análisis Costo-Beneficio, Biòpsia, Models, Econometric, Assaigs clínics

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39387325
https://hdl.handle.net/2445/216391
https://hdl.handle.net/20.500.13003/21130

Sustained Clinical Benefit and Intracranial Activity of Tarlatamab in Previously Treated Small Cell Lung Cancer: DeLLphi-300 Trial Update

Authors: Afshin Dowlati Horst-Dieter Hummel Stephane Champiat et al.

Contributors: Afshin Dowlati Horst-Dieter Hummel Stephane Champiat et al.

Source: J Clin Oncol
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname
Journal of clinical oncology, vol. 42, no. 29, pp. 3392-3399

Subject Terms: Adult, Male, 0301 basic medicine, Lung Neoplasms, Other subheadings::Other subheadings::/therapeutic use, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, DISEASES::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Brain Neoplasms, Otros calificadores::Otros calificadores::/uso terapéutico, Medicaments antineoplàstics - Ús terapèutic, Pulmons - Càncer - Immunoteràpia, 03 medical and health sciences, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias torácicas::neoplasias del tracto respiratorio::neoplasias pulmonares::neoplasias de los bronquios::carcinoma broncogénico::carcinoma pulmonar de células pequeñas, 0302 clinical medicine, COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antineoplásicos::inmunoterapia antineoplásica, CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents::Antineoplastic Agents, Immunological, Humans, DISEASES::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms::Bronchial Neoplasms::Carcinoma, Bronchogenic::Small Cell Lung Carcinoma, Cervell - Càncer - Immunoteràpia, Aged, Aged, 80 and over, Other subheadings::Other subheadings::Other subheadings::/drug therapy, Brain Neoplasms, Small Cell Lung Carcinoma/drug therapy, Small Cell Lung Carcinoma/pathology, Lung Neoplasms/drug therapy, Lung Neoplasms/pathology, Middle Aged, Female, Brain Neoplasms/drug therapy, Small Cell Lung Carcinoma, CLINICAL TRIAL UPDATES, ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema nervioso::neoplasias del sistema nervioso central::neoplasias cerebrales

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39208379
https://hdl.handle.net/11351/12617
https://serval.unil.ch/resource/serval:BIB_BCFC9F2CF9BF.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_BCFC9F2CF9BF
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_BCFC9F2CF9BF8

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Authors: Ferdinandos Skoulidis Haniel A. Araujo Minh Truong Do et al.

Source: Nature
Nature, vol. 635, no. 8038, pp. 462-471
Nature, vol 635, iss 8038

Subject Terms: Male, Lung Neoplasms, General Science & Technology (science-metrix), T-Lymphocytes, Monoclonal (mesh), Drug Resistance, Nitric Oxide Synthase Type II, Phase III as Topic (mesh), Lung (rcdc), B7-H1 Antigen, Mice, AMP-Activated Protein Kinase Kinases, Carcinoma, Non-Small-Cell Lung, Monoclonal, Tumor Microenvironment, Animals (mesh), T-Lymphocytes (mesh), CTLA-4 Antigen, Non-Small-Cell Lung, 32 Biomedical and Clinical Sciences (for-2020), Male (mesh), Immune Checkpoint Inhibitors, Cancer (rcdc), Humans (mesh), Kelch-Like ECH-Associated Protein 1/metabolism, Kelch-Like ECH-Associated Protein 1/genetics, Humans, Animals, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/genetics, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/immunology, Protein Serine-Threonine Kinases/metabolism, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Serine-Threonine Kinases/genetics, Immune Checkpoint Inhibitors/pharmacology, Immune Checkpoint Inhibitors/therapeutic use, Drug Resistance, Neoplasm/drug effects, Lung Neoplasms/drug therapy, Lung Neoplasms/genetics, Lung Neoplasms/immunology, Lung Neoplasms/pathology, CTLA-4 Antigen/antagonists & inhibitors, CTLA-4 Antigen/metabolism, B7-H1 Antigen/metabolism, B7-H1 Antigen/antagonists & inhibitors, Female, Mutation, Antibodies, Monoclonal, Kelch-Like ECH-Associated Protein 1, Immune Checkpoint Inhibitors (mesh), Mutation (mesh), Mice (mesh), Tumor Suppressor (mesh), Nitric Oxide Synthase Type II (mesh), Phase III as Topic, Lung Cancer (rcdc), Non-Small-Cell Lung (mesh), Neoplasm (mesh), Tumor Suppressor, Tumor Suppressor Proteins (mesh), Antibodies, Article, CTLA-4 Antigen (mesh), 5.1 Pharmaceuticals (hrcs-rac), Clinical Trials, 3204 Immunology (for-2020), AMP-Activated Protein Kinase Kinases (mesh), Lung Neoplasms (mesh), Kelch-Like ECH-Associated Protein 1 (mesh), Tumor Suppressor Proteins, Carcinoma, Immunotherapy (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Cancer (hrcs-hc), B7-H1 Antigen (mesh), Tumor Microenvironment (mesh), 3211 Oncology and Carcinogenesis (for-2020), Genes, Clinical Trials, Phase III as Topic, Drug Resistance, Neoplasm, Female (mesh), Neoplasm

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Access URL: https://pubmed.ncbi.nlm.nih.gov/39385035
https://serval.unil.ch/notice/serval:BIB_CF6BDAC4D159
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_CF6BDAC4D1593
https://serval.unil.ch/resource/serval:BIB_CF6BDAC4D159.P001/REF.pdf
https://escholarship.org/content/qt7qr2m860/qt7qr2m860.pdf
https://escholarship.org/uc/item/7qr2m860

TTF-1 is a highly sensitive but not fully specific marker for pulmonary and thyroidal cancer: a tissue microarray study evaluating more than 17,000 tumors from 152 different tumor entities

Authors: Katharina Möller Tayyaba Gulzar Maximilian Lennartz et al.

Source: Virchows Arch

Subject Terms: Lung Neoplasms, Thyroid Nuclear Factor 1, Nuclear Proteins, Adenocarcinoma, Sensitivity and Specificity, Immunohistochemistry, Tissue Array Analysis, Transcription Factors/analysis [MeSH], Lung Neoplasms/diagnosis [MeSH], TTF-1, Aspartic Acid Endopeptidases [MeSH], Tissue Array Analysis [MeSH], Tissue microarray, Adenocarcinoma/metabolism [MeSH], Original Article, Nuclear Proteins/metabolism [MeSH], Sensitivity and Specificity [MeSH], Thyroid Neoplasms/metabolism [MeSH], Adenocarcinoma/pathology [MeSH], Diagnosis, Transcription Factors/metabolism [MeSH], Biomarkers, Tumor/analysis [MeSH], Nuclear Proteins/analysis [MeSH], Thyroid Neoplasms/diagnosis [MeSH], Thyroid Nuclear Factor 1/analysis [MeSH], Humans [MeSH], Pulmonary adenocarcinomas, Thyroid Neoplasms/pathology [MeSH], Immunohistochemistry [MeSH], Lung Neoplasms/pathology [MeSH], Adenocarcinoma/diagnosis [MeSH], Lung Neoplasms/metabolism [MeSH], Thyroid Nuclear Factor 1/metabolism [MeSH], Biomarkers, Tumor, Humans, Aspartic Acid Endopeptidases, Thyroid Neoplasms, Transcription Factors

Access URL: https://pubmed.ncbi.nlm.nih.gov/39377914
https://repository.publisso.de/resource/frl:6504593

KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma

Authors: Jan Budczies Eva Romanovsky Martina Kirchner et al.

Source: Br J Cancer
British journal of cancer, vol. 131, no. 3, pp. 524-533

Subject Terms: Male, Aged, 80 and over, Adult, 0301 basic medicine, Lung Neoplasms, Adenocarcinoma of Lung, Middle Aged, Prognosis, Article, Aged, 80 and over [MeSH], Aged [MeSH], Lung Neoplasms/genetics [MeSH], 692/53/2423, Cohort Studies [MeSH], Proto-Oncogene Proteins p21(ras)/genetics [MeSH], Immunotherapy/methods [MeSH], Male [MeSH], Adenocarcinoma of Lung/genetics [MeSH], 631/67/1612/1350, Lung Neoplasms/immunology [MeSH], 631/114/2415, Female [MeSH], Adenocarcinoma of Lung/drug therapy [MeSH], Mutation [MeSH], Adult [MeSH], Humans [MeSH], Middle Aged [MeSH], Adenocarcinoma of Lung/immunology [MeSH], Tumor Suppressor Protein p53/genetics [MeSH], Immune Checkpoint Inhibitors/therapeutic use [MeSH], 631/208/69, Biomarkers, Tumor/genetics [MeSH], Prognosis [MeSH], Lung Neoplasms/pathology [MeSH], Lung Neoplasms/drug therapy [MeSH], Adenocarcinoma of Lung/pathology [MeSH], article, Proto-Oncogene Proteins p21(ras), Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Humans, Tumor Suppressor Protein p53/genetics, Mutation, Proto-Oncogene Proteins p21(ras)/genetics, Female, Adenocarcinoma of Lung/genetics, Adenocarcinoma of Lung/drug therapy, Adenocarcinoma of Lung/immunology, Adenocarcinoma of Lung/pathology, Immune Checkpoint Inhibitors/therapeutic use, Lung Neoplasms/genetics, Lung Neoplasms/drug therapy, Lung Neoplasms/pathology, Lung Neoplasms/immunology, Aged, Biomarkers, Tumor/genetics, Immunotherapy/methods, Biomarkers, Tumor, Immunotherapy, Tumor Suppressor Protein p53, Immune Checkpoint Inhibitors

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38866964
https://serval.unil.ch/notice/serval:BIB_0BE58CAF6E6A
https://serval.unil.ch/resource/serval:BIB_0BE58CAF6E6A.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0BE58CAF6E6A7
https://repository.publisso.de/resource/frl:6518703

Acute Hypoxia Does Not Alter Tumor Sensitivity to FLASH Radiation Therapy

Authors: Ron J. Leavitt Aymeric Almeida Veljko Grilj et al.

Source: International journal of radiation oncology, biology, physics, vol. 119, no. 5, pp. 1493-1505
International journal of radiation oncology, biology, physics

Subject Terms: Computer. Automation, Lung Neoplasms, Pyridones, Pyrimidinones, Cell Cycle Checkpoints, Carbon Dioxide, Radiation Tolerance, Oxidative Phosphorylation, 3. Good health, Oxygen, Animals, Humans, Mice, Pyrimidinones/pharmacology, Pyrimidinones/therapeutic use, Tumor Hypoxia, Glioblastoma/radiotherapy, Glioblastoma/metabolism, Glycolysis, Pyridones/pharmacology, Pyridones/therapeutic use, Nitroimidazoles, Cell Line, Tumor, Lung Neoplasms/radiotherapy, Lung Neoplasms/pathology, Lung Neoplasms/metabolism, Head and Neck Neoplasms/radiotherapy, Cell Cycle Checkpoints/radiation effects, Oxygen/metabolism, Head and Neck Neoplasms, Human medicine, Glioblastoma

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38387809
https://serval.unil.ch/resource/serval:BIB_44E104806F28.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_44E104806F28
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_44E104806F289
https://repository.uantwerpen.be/docstore/d:irua:24893
https://hdl.handle.net/10067/2076170151162165141

Elevated expression of complement factor I in lung cancer cells associates with shorter survival–Potentially via non-canonical mechanism

Authors: Anna Felberg Michał Bieńkowski Tomasz Stokowy et al.

Source: Translational Research. 269:1-13

Subject Terms: Male, Complement system, Lung Neoplasms, NSCLC, Cell Line, Non-Small-Cell Lung/metabolism, Cell Line, Tumor, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms/pathology, Humans, innate immunity, complement system, Aged, Complement Factor I/metabolism, Innate immunity, Neoplastic, Tumor, Carcinoma, Middle Aged, Prognosis, Immunohistochemistry, Gene Expression Regulation, Neoplastic, lung cancer, Gene Expression Regulation, Complement Factor I, immunohistochemistry, Female, Lung cancer

Access URL: https://pubmed.ncbi.nlm.nih.gov/38395390
https://pure.amsterdamumc.nl/en/publications/e3baec90-6cb4-41cf-9a2c-3c0cbd021ddf
https://doi.org/10.1016/j.trsl.2024.02.003

Unveiling the Landscape of Uncommon EGFR Mutations in NSCLC-A Systematic Review

Authors: Maxime Borgeaud Kaushal Parikh Giuseppe Luigi Banna et al.

Source: Journal of Thoracic Oncology. 19:973-983

Subject Terms: Tyrosine kinase inhibitors, Uncommon EGFR mutations, Lung Neoplasms / genetics, 0301 basic medicine, Lung Neoplasms, Lung Neoplasms / pathology, EGFR PACC mutations, Lung Neoplasms / drug therapy, 3. Good health, ErbB Receptors, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung / pathology, Carcinoma, Non-Small-Cell Lung, Mutation, Systematic review, Non–small cell lung cancer, Carcinoma, Non-Small-Cell Lung / genetics, Humans, Carcinoma, Non-Small-Cell Lung / drug therapy, Protein Kinase Inhibitors / therapeutic use, ErbB Receptors / genetics, Protein Kinase Inhibitors

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38499147

Repeated Anatomical Pulmonary Resection for Second Primary Nonsmall‐Cell Lung Cancer: Safety and Short‐Term Outcomes

Authors: Céline Forster Louis‐Emmanuel Chriqui Etienne Abdelnour‐Berchtold et al.

Source: Thorac Cancer
Thoracic Cancer, Vol 16, Iss 12, Pp n/a-n/a (2025)
Thoracic cancer, vol. 16, no. 12, pp. e70116

Subject Terms: lobectomy, Humans, Carcinoma, Non-Small-Cell Lung/surgery, Carcinoma, Non-Small-Cell Lung/pathology, Male, Female, Aged, Middle Aged, Lung Neoplasms/surgery, Lung Neoplasms/pathology, Pneumonectomy/methods, Retrospective Studies, Thoracic Surgery, Video-Assisted/methods, Neoplasms, Second Primary/surgery, Neoplasms, Second Primary/pathology, Treatment Outcome, VATS, nonsmall‐cell lung cancer, segmentectomy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Original Article, RC254-282

File Description: application/pdf

Access URL: https://doaj.org/article/b3742fb62e3d4cca896dead345be92d3
https://serval.unil.ch/notice/serval:BIB_50552D2A445D
https://serval.unil.ch/resource/serval:BIB_50552D2A445D.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_50552D2A445D5

Depletion-dependent activity-based protein profiling using SWATH/DIA-MS detects serine hydrolase lipid remodeling in lung adenocarcinoma progression

Authors: Sajic, Tatjana Vizovišek, Matej Arni, Stephan et al.

Contributors: Sajic, Tatjana Vizovišek, Matej Arni, Stephan et al.

Source: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-24 (2025)
Nature communications, vol. 16, no. 1, pp. 4889
Nature Communications, 16 (1)

Subject Terms: Humans, Lung Neoplasms/pathology, Lung Neoplasms/metabolism, Lung Neoplasms/enzymology, Adenocarcinoma of Lung/pathology, Adenocarcinoma of Lung/metabolism, Adenocarcinoma of Lung/genetics, Adenocarcinoma of Lung/enzymology, Proteomics/methods, Disease Progression, Mass Spectrometry/methods, Proteome/metabolism, Lipid Metabolism, 10255 Clinic for Thoracic Surgery, 1300 General Biochemistry, Genetics and Molecular Biology, Science, 610 Medicine & health, 1600 General Chemistry, 3100 General Physics and Astronomy, Article

File Description: application/pdf; application/application/pdf; ZORA278830.pdf - application/pdf

Access URL: https://doaj.org/article/5ed40093c17942c4ad588f09639912ce
https://serval.unil.ch/resource/serval:BIB_A8042DF76EC3.P001/REF.pdf
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http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A8042DF76EC34
http://hdl.handle.net/20.500.11850/739221
https://www.zora.uzh.ch/id/eprint/278830/
https://doi.org/10.5167/uzh-278830

Incidence and features of pulmonary track nodules after CT-guided lung biopsy with track sealing using gelatin sponge slurry

Authors: Grandjean, Flavien Withofs, Nadia Detrembleur, Nancy et al.

Source: BMC Med Imaging
BMC Medical Imaging, Vol 25, Iss 1, Pp 1-8 (2025)

Subject Terms: Male, Image-Guided Biopsy, Adult, Radiology, Nuclear Medicine and Imaging, Lung Neoplasms, Lung/pathology, Tomography, X-Ray Computed/methods, Lung Neoplasms/diagnostic imaging, Sciences de la santé humaine, Lung/diagnostic imaging, Solitary Pulmonary Nodule/epidemiology, Solitary Pulmonary Nodule/pathology, Medical technology, Lung Neoplasms/pathology, Humans, Track sealant, Human health sciences, R855-855.5, Image-Guided Biopsy/adverse effects, Lung, Retrospective Studies, Aged, Gelatin sponge, Aged, 80 and over, Pneumothorax/etiology, Research, Incidence, Radiologie, médecine & imagerie nucléaire, Pneumothorax, Solitary Pulmonary Nodule, Middle Aged, CT-guided lung biopsy, Pneumothorax/prevention & control, Solitary Pulmonary Nodule/diagnostic imaging, Gelatin, Image-Guided Biopsy/methods, Female, Tomography, X-Ray Computed, Radiology, nuclear medicine & imaging

Access URL: https://pubmed.ncbi.nlm.nih.gov/40175914
https://doaj.org/article/9c5ec4fb2d0d44eebcd254eb034ebb9b
https://hdl.handle.net/2268/336608
https://doi.org/10.1186/s12880-025-01644-x

Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial

Authors: Solange Peters Shirish M. Gadgeel Tony Mok et al.

Source: Nat Med
Nature medicine, vol. 30, no. 7, pp. 1923-1932

Subject Terms: Male, Adult, Aged, 80 and over, Indazoles, Lung Neoplasms, Liquid Biopsy, Middle Aged, Protein-Tyrosine Kinases, Article, 3. Good health, Carcinoma, Non-Small-Cell Lung, Proto-Oncogene Proteins, Benzamides, Biomarkers, Tumor, Humans, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/genetics, Carcinoma, Non-Small-Cell Lung/pathology, Indazoles/therapeutic use, Indazoles/adverse effects, Benzamides/therapeutic use, Lung Neoplasms/drug therapy, Lung Neoplasms/genetics, Lung Neoplasms/pathology, Female, Aged, Proto-Oncogene Proteins/genetics, Proto-Oncogene Proteins/metabolism, Protein-Tyrosine Kinases/antagonists & inhibitors, Protein-Tyrosine Kinases/genetics, Biomarkers, Tumor/genetics, Biomarkers, Tumor/metabolism, Protein Kinase Inhibitors/therapeutic use, Protein Kinase Inhibitors/adverse effects, Protein Kinase Inhibitors

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Access URL: https://pubmed.ncbi.nlm.nih.gov/38898120
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