Výsledky vyhľadávania - "Longevity: physiology"

Mimetic AI & NAD⁺: A Polymorphic Injector for Longevity Science, Industry, and Society

Autori: Tabary, Frédéric

Predmety: Sirtuins/biosynthesis, Sirtuins/economics, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/physiology, #EpigeneticClock, MTOR Inhibitors/standards, Sirtuins/pharmacokinetics, MTOR Inhibitors/isolation & purification, Sirtuins/genetics, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/analysis, (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride/administration & dosage, MTOR Inhibitors/history, MTOR Inhibitors/metabolism, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/metabolism, MTOR Inhibitors/pharmacokinetics, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/history, MTOR Inhibitors/therapeutic use, Sirtuins, MTOR Inhibitors/urine, Sirtuins/deficiency, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/biosynthesis, MTOR Inhibitors/chemistry, MTOR Inhibitors/classification, MTOR Inhibitors/pharmacology, Zoran IA mimetique, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/toxicity, MTOR Inhibitors/blood, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/economics, (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride, Longevity/genetics, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/urine, Sirtuins/classification, MTOR Inhibitors, Sirtuins/ultrastructure, #IA_Mimétique, Sirtuins/urine, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/ultrastructure, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/genetics, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/chemistry, mTOR, zoran, MTOR Inhibitors/chemical synthesis, Longevity/ethics, BiomimeticPeptides, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/classification, Compliance, MTOR Inhibitors/immunology, Longevity/drug effects, #MimeticAI, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/immunology, Sirtuins/standards, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/blood, #LongevityStandards, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/poisoning, Longevity, NR, AICompliance, #Geroprotectors, Longevity/physiology, longevity standards, AIforHealthspan, Sirtuins/physiology, SilverEconomyAI, OpenSourceAI, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases, Sirtuins/blood, Sirtuins/toxicity, MTOR Inhibitors/analysis, LongevityDigitalTwins, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/pharmacology, MTOR Inhibitors/poisoning, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/standards, NMN, LongevityAI, Sirtuins/metabolism, MTOR Inhibitors/toxicity, Longevity/radiation effects, (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride/adverse effects, NAD, MTOR Inhibitors/administration & dosage, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/deficiency, Sirtuins/chemistry, Sirtuins/poisoning, Longevity/immunology, Sirtuins/immunology, Compliance/physiology, MTOR Inhibitors/cerebrospinal fluid, Resveratrol, #CellularReprogramming, Patient Compliance, NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases/pharmacokinetics, MTOR Inhibitors/economics, Sirtuins/history, Sirtuins/pharmacology, #MultiOmicsAI, Sirtuins/analysis

Biological Foundations of Universal Sexual Transition ; There Is No Menopause/Andropause Later Life as Universal Sexual Transition

Autori: Blatt, Kate Lynn

Prispievatelia: Blatt, Kate Lynn

Predmety: Longevity, Longevity/genetics, Longevity/physiology, Longevity/ethics, Longevity/immunology, Longevity/drug effects, Longevity/radiation effects

Relation: https://zenodo.org/records/17211857; oai:zenodo.org:17211857; https://doi.org/10.5281/zenodo.17211857

Dostupnosť: https://doi.org/10.5281/zenodo.17211857
https://zenodo.org/records/17211857

Biological Foundations of Universal Sexual Transition

Autori: Blatt, Kate Lynn

Prispievatelia: Blatt, Kate Lynn

Predmety: Longevity, Longevity/genetics, Longevity/physiology, Longevity/ethics, Longevity/immunology, Longevity/drug effects, Longevity/radiation effects

Relation: https://zenodo.org/records/17203222; oai:zenodo.org:17203222; https://doi.org/10.5281/zenodo.17203222

Dostupnosť: https://doi.org/10.5281/zenodo.17203222
https://zenodo.org/records/17203222

How Women Become Men With Age: Post-Menopausal Hormonal Shift, Androgenic Drift, and Gendered Identity Change in Aging Females

Autori: Blatt, Kate Lynn

Prispievatelia: Blatt, Kate Lynn

Predmety: Longevity, Longevity/genetics, Longevity/physiology, Longevity/ethics, Longevity/immunology, Longevity/drug effects, Longevity/radiation effects, longivity

Relation: https://zenodo.org/records/17186220; oai:zenodo.org:17186220; https://doi.org/10.5281/zenodo.17186220

Dostupnosť: https://doi.org/10.5281/zenodo.17186220
https://zenodo.org/records/17186220

How Men Become Women With Age Hormonal Decline, Phenotypic Drift, and Gendered Identity Change in the Aging Male

Autori: Blatt, Kate Lynn

Prispievatelia: Blatt, Kate Lynn

Predmety: Longevity, Longevity/genetics, Longevity/physiology, Longevity/ethics, Longevity/immunology, Longevity/drug effects, Longevity/radiation effects

Relation: https://zenodo.org/records/17186121; oai:zenodo.org:17186121; https://doi.org/10.5281/zenodo.17186121

Dostupnosť: https://doi.org/10.5281/zenodo.17186121
https://zenodo.org/records/17186121

Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation

Autori: Johannes Krug Birgit Perner Carolin Albertz a ďalší

Zdroj: eLife
eLife, Vol 12 (2023)
eLife, 12

Predmety: transparency, Mammals, 0301 basic medicine, Aging, senescence, QH301-705.5, Science, Longevity, 03 medical and health sciences, Fundulidae, Zebrafish/genetics, Aging/genetics [MeSH], Animals [MeSH], Clustered Regularly Interspaced Short Palindromic Repeats, Aging/genetics, Fundulidae [MeSH], Longevity/physiology [MeSH], Mammals/genetics, Animals, Clustered Regularly Interspaced Short Palindromic Repeats [MeSH], Longevity/physiology, Mammals/genetics [MeSH], Zebrafish/genetics [MeSH], killifish, Medicine, pigmentation, mate choice, Biology (General), Zebrafish, Developmental Biology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36820520
https://doaj.org/article/69a7a43d1e33468da4ab950279b3ab01
https://repository.publisso.de/resource/frl:6475422

Longevity biotechnology:bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

Autori: Lyu, Yu-Xuan Fu, Qiang Wilczok, Dominika a ďalší

Zdroj: Lyu, Y-X, Fu, Q, Wilczok, D, Ying, K, King, A, Antebi, A, Vojta, A, Stolzing, A, Moskalev, A, Georgievskaya, A, Maier, A B, Olsen, A, Groth, A, Simon, A K, Brunet, A, Jamil, A, Kulaga, A, Bhatti, A, Yaden, B, Pedersen, B K, Schumacher, B, Djordjevic, B, Kennedy, B, Chen, C, Huang, C Y, Correll, C U, Murphy, C T, Ewald, C Y, Chen, D, Valenzano, D R, Sołdacki, D, Erritzoe, D, Meyer, D, Sinclair, D A, Chini, E N, Teeling, E C, Morgen, E, Verdin, E, Vernet, E, Pinilla, E, Fang, E F, Bischof, E, Mercken, E M, ....

Predmety: Humans, Aging/physiology, Artificial Intelligence, Biomarkers/metabolism, Biotechnology/methods, Geroscience/methods, Longevity/physiology

Dostupnosť: https://research.vu.nl/en/publications/be232d5f-2c88-4f42-af2a-d173ea5cd579
https://doi.org/10.18632/aging.206135
https://hdl.handle.net/1871.1/be232d5f-2c88-4f42-af2a-d173ea5cd579

Fast-lived Hosts and Zoonotic Risk

Autori: Gregory F. Albery Daniel J. Becker

Zdroj: Trends in Parasitology. 37:117-129

Predmety: Risk, life history, 0106 biological sciences, 0301 basic medicine, disease ecology, Time Factors, Longevity, ecoimmunology, bats, bat, 01 natural sciences, Host-Parasite Interactions, emerging infectious diseases, 03 medical and health sciences, Human-Animal Interaction, Zoonoses, Chiroptera, Parasitic Diseases, Longevity/*physiology, Animals, Humans, Animalia, Chordata, Disease Reservoirs, zoonosis, Zoonoses/*immunology/*parasitology/transmission, Biodiversity, Host-Parasite Interactions/*immunology, Biological Evolution, Mammalia, Disease Reservoirs/parasitology, Parasitic Diseases/*transmission

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33214097
https://www.sciencedirect.com/science/article/pii/S147149222030297X
https://www.cell.com/trends/parasitology/fulltext/S1471-4922(20)30297-X
https://www.ncbi.nlm.nih.gov/pubmed/33214097
https://pubmed.ncbi.nlm.nih.gov/33214097/
http://www.ncbi.nlm.nih.gov/pubmed/33214097

Cross-species functional modules link proteostasis to human normal aging.

Autori: Komljenovic, A. Li, H. Sorrentino, V. a ďalší

Predmety: Adult, Aged, Aging/genetics, Aging/metabolism, Animals, Caenorhabditis elegans, Caloric Restriction, Computational Biology, Drosophila melanogaster, Evolution, Molecular, Female, Gene Expression Profiling, Genetic Markers, Humans, Longevity/genetics, Longevity/physiology, Male, Mice, Middle Aged, Models, Biological, Proteostasis/genetics, Species Specificity, Young Adult

Popis súboru: application/pdf

Relation: PLoS Computational Biology; https://iris.unil.ch/handle/iris/235538; serval:BIB_DB3E6C72F674; 000481577700029

Dostupnosť: https://iris.unil.ch/handle/iris/235538
https://doi.org/10.1371/journal.pcbi.1007162

Social insects as a model to study the molecular basis of ageing

Autori: Keller, L. Jemielity, S.

Predmety: Aging/genetics/*physiology Animals Antioxidants/physiology Ants/genetics/*physiology Bees/genetics/*physiology Female Gene Expression Regulation/physiology Juvenile Hormones/physiology Longevity/physiology Male *Models, Biological Telomere/physiology Vitellogenins/physiology

Popis súboru: application/pdf

Relation: Experimental gerontology; https://iris.unil.ch/handle/iris/213550; serval:BIB_79D6EB631B96; 000238899600001

Dostupnosť: https://iris.unil.ch/handle/iris/213550
https://doi.org/10.1016/j.exger.2006.04.002

Cellular and molecular longevity pathways: the old and the new.

Autori: Nikoletopoulou, V. Kyriakakis, E. Tavernarakis, N.

Predmety: Aging/genetics, Aging/physiology, Humans, Longevity/genetics, Longevity/physiology, Signal Transduction/genetics, Signal Transduction/physiology, aging, inflammation, microbiota, senescence, stem cells, stress response

Relation: Trends in Endocrinology & Metabolism; https://iris.unil.ch/handle/iris/204461; serval:BIB_CDAA1A0B41F4; 000338756000006

Dostupnosť: https://iris.unil.ch/handle/iris/204461
https://doi.org/10.1016/j.tem.2013.12.003

Sex-specific effects of interventions that extend fly life span.

Autori: Burger, J.M. Promislow, D.E.

Predmety: Animals, Drosophila melanogaster/genetics, Drosophila melanogaster/physiology, Female, Longevity/genetics, Longevity/physiology, Male, Sex Factors

Relation: Science of Aging Knowledge Environment; 1539-6150[electronic]; https://iris.unil.ch/handle/iris/189490; serval:BIB_8F6257A5AA09

Dostupnosť: https://iris.unil.ch/handle/iris/189490
https://doi.org/10.1126/sageke.2004.28.pe30

What are the effects of maternal and pre-adult environments on ageing in humans, and are there lessons from animal models?

Autori: Brakefield, P. M. Gems, D. Cowen, T. a ďalší

Predmety: Adaptation, Physiological Animals Caloric Restriction Environment *Evolution Humans Longevity/*physiology Models, Animal *Phenotype

Popis súboru: application/pdf

Relation: Mechanisms of Ageing and Development; https://iris.unil.ch/handle/iris/153839; serval:BIB_B457EC4DF345; 000226945100009

Dostupnosť: https://iris.unil.ch/handle/iris/153839
https://doi.org/10.1016/j.mad.2004.07.013

Physiological increase of yolk testosterone level does not affect oxidative status and telomere length in gull hatchlings.

Autori: Parolini, M. Possenti, C.D. Romano, A. a ďalší

Predmety: Androgens/metabolism, Animals, Antioxidants/metabolism, Charadriiformes/metabolism, Charadriiformes/physiology, Egg Yolk/metabolism, Embryo, Nonmammalian/metabolism, Longevity/physiology, Oxidation-Reduction, Oxidative Stress/physiology, Reactive Oxygen Species/metabolism, Telomere/metabolism, Testosterone/metabolism

Popis súboru: application/pdf

Relation: PLoS ONE; https://iris.unil.ch/handle/iris/143835; serval:BIB_7DDCDC3F2F90; 000448448700058

Dostupnosť: https://iris.unil.ch/handle/iris/143835
https://doi.org/10.1371/journal.pone.0206503

The functional costs and benefits of dietary restriction in Drosophila.

Autori: Burger, J.M. Hwangbo, D.S. Corby-Harris, V. a ďalší

Predmety: Aging/physiology, Animals, Caloric Restriction, Cold Temperature/adverse effects, Drosophila melanogaster/physiology, Female, Fertility/physiology, Food Deprivation/physiology, Immune System/physiology, Immunity, Innate/physiology, Longevity/physiology, Male, Oxidative Stress/physiology, Starvation/metabolism, Stress, Physiological/metabolism

Relation: Aging Cell; https://iris.unil.ch/handle/iris/133608; serval:BIB_9EE21DABBFA1; 000243633700007

Dostupnosť: https://iris.unil.ch/handle/iris/133608
https://doi.org/10.1111/j.1474-9726.2006.00261.x

Learning ability and longevity: a symmetrical evolutionary trade-off in Drosophila.

Autori: Burger, J.M. Kolss, M. Pont, J. a ďalší

Predmety: Animals, Body Weight, Drosophila melanogaster/physiology, Evolution, Fertility/physiology, Learning/physiology, Longevity/physiology, Selection, Genetic

Relation: Evolution; 0014-3820[print], 0014-3820[linking]; https://iris.unil.ch/handle/iris/132540; serval:BIB_73688A4ADCCB; 000256356300002

Dostupnosť: https://iris.unil.ch/handle/iris/132540
https://doi.org/10.1111/j.1558-5646.2008.00376.x

Endocrine uncoupling of the trade-off between reproduction and somatic maintenance in eusocial insects.

Autori: Rodrigues, M.A. Flatt, T.

Predmety: Animals, Insecta/physiology, Juvenile Hormones/metabolism, Longevity/physiology, Reproduction/physiology, Social Behavior, Vitellogenins/metabolism

Relation: Current Opinion in Insect Science; https://iris.unil.ch/handle/iris/119873; serval:BIB_5F08D8A3C639; 000386405600003

Dostupnosť: https://iris.unil.ch/handle/iris/119873
https://doi.org/10.1016/j.cois.2016.04.013

Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span.

Autori: Gat-Yablonski, G. Finka, A. Pinto, G. a ďalší

Predmety: Aging/metabolism, Animals, Eating/physiology, Feeding Behavior/physiology, Food Deprivation, HSP70 Heat-Shock Proteins/metabolism, HSP90 Heat-Shock Proteins/metabolism, Homeostasis/physiology, Liver/metabolism, Longevity/physiology, Proteomics, Rats, aging, catch up growth, food restriction, heat shock proteins, mitochondria

Popis súboru: application/pdf

Relation: Aging; https://iris.unil.ch/handle/iris/108764; serval:BIB_290FCC29088F; 000383287300014

Dostupnosť: https://iris.unil.ch/handle/iris/108764
https://doi.org/10.18632/aging.101009

Proteome size is positively correlated with lifespan in mammals but negatively correlated with lifespan in birds

Autori: Morimoto Borges, Juliano Pietras , Zuzanna University of Aberdeen.Mathematical Science

Prispievatelia: Morimoto Borges, Juliano Pietras , Zuzanna University of Aberdeen.Mathematical Science

Predmety: comparative genetics, dietary restriction, trade-offs, comparative genomics, Animals, Proteomics, Birds/physiology, Longevity/physiology, Mammals/physiology, Proteome/metabolism, QL Zoology, Biomaterials, Biomedical Engineering, General Biochemistry,Genetics and Molecular Biology, Supplementary Data, DAS, Link, QL

Popis súboru: application/pdf

Relation: Advanced Biology; 300942148; 85219207881; Morimoto Borges , J & Pietras , Z 2025 , ' Proteome size is positively correlated with lifespan in mammals but negatively correlated with lifespan in birds ' , Advanced Biology , vol. 9 , no. 4 , 2400633 . https://doi.org/10.1002/adbi.202400633; https://hdl.handle.net/2164/25110; http://www.scopus.com/inward/record.url?scp=85219207881&partnerID=8YFLogxK; https://github.com/jmor2753/advbiol_2025_proteome

Dostupnosť: https://hdl.handle.net/2164/25110
https://doi.org/10.1002/adbi.202400633
http://www.scopus.com/inward/record.url?scp=85219207881&partnerID=8YFLogxK
https://github.com/jmor2753/advbiol_2025_proteome

Fecundity and survival in relation to resistance to oxidative stress in a free-living bird.

Autori: Bize, P. Devevey, G. Monaghan, P. a ďalší

Predmety: Animals, Fertility/physiology, Longevity/physiology, Oxidative Stress/physiology, Songbirds/physiology

Popis súboru: application/pdf

Relation: Ecology; 0012-9658[print], 0012-9658[linking]; https://iris.unil.ch/handle/iris/222589; serval:BIB_BB3F1B58335F; 000259259300024

Dostupnosť: https://iris.unil.ch/handle/iris/222589
https://doi.org/10.1890/07-1135.1