Suchergebnisse - "Liquid Chromatography-Mass Spectrometry"

Significant improvements in targeted UHPLC-ESI-MS/MS analysis of the reactive aldehydes 4-hydroxy-2(E)-nonenal and 4-hydroxy-2(E)-hexenal and application to rat serum.

Autoren: Chevolleau S Orlandi C Mervant L et al.

Quelle: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Nov 01; Vol. 1265, pp. 124747. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Aldehydes*/blood , Colorectal Neoplasms*/blood , Colorectal Neoplasms*/etiology , Liquid Chromatography-Mass Spectrometry*/methods , Red Meat*/adverse effects, Animals ; Rats ; Lipid Peroxidation ; Rats, Inbred F344 ; Sensitivity and Specificity

Quantitative analysis of ethylene precursor ACC in plant samples by liquid chromatography-tandem mass spectrometry.

Autoren: Tong J Zhao W Wang K et al.

Quelle: BMC plant biology [BMC Plant Biol] 2025 Jul 17; Vol. 25 (1), pp. 920. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100967807 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2229 (Electronic) Linking ISSN: 14712229 NLM ISO Abbreviation: BMC Plant Biol Subsets: MEDLINE

MeSH-Schlagworte: Ethylenes* , Liquid Chromatography-Mass Spectrometry*/economics , Liquid Chromatography-Mass Spectrometry*/methods , Amino Acids, Cyclic*/analysis , Amino Acids, Cyclic*/isolation & purification , Amino Acids, Cyclic*/metabolism , Plants*/chemistry , Plants*/metabolism, Plant Growth Regulators/analysis ; Plant Growth Regulators/chemistry ; Plant Growth Regulators/isolation & purification ; Plant Physiological Phenomena ; Stress, Physiological ; Liquid Phase Microextraction ; Fruit/chemistry ; Fruit/metabolism

Enhancing Herbal Formulation Analysis: The Role of Flash Chromatography and TLC-MS in Purification and Quality Control.

Autoren: Shukla S Mevada S

Quelle: Journal of mass spectrometry : JMS [J Mass Spectrom] 2025 Sep; Vol. 60 (9), pp. e5172.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 9504818 Publication Model: Print Cited Medium: Internet ISSN: 1096-9888 (Electronic) Linking ISSN: 10765174 NLM ISO Abbreviation: J Mass Spectrom Subsets: MEDLINE

MeSH-Schlagworte: Chromatography, Thin Layer*/methods , Liquid Chromatography-Mass Spectrometry*/methods , Plant Extracts*/analysis , Plant Extracts*/chemistry , Plant Extracts*/standards , Phytochemicals*/isolation & purification, Quality Control

Enhancing addiction care: Benefits of urinary screening with LC-HRMS (liquid chromatography-high resolution mass spectrometry) for psychoactive substances and drugs.

Autoren: Le Carpentier E Helesbeux M Biering V et al.

Quelle: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2025 Aug 30; Vol. 141, pp. 111465. Date of Electronic Publication: 2025 Aug 10.

Publikationsart: Comparative Study; Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 8211617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4216 (Electronic) Linking ISSN: 02785846 NLM ISO Abbreviation: Prog Neuropsychopharmacol Biol Psychiatry Subsets: MEDLINE

MeSH-Schlagworte: Substance Abuse Detection*/methods , Substance-Related Disorders*/diagnosis , Substance-Related Disorders*/urine , Liquid Chromatography-Mass Spectrometry*/methods , Psychotropic Drugs*/urine , Urinalysis*/methods, Substance Abuse Treatment Centers ; Multivariate Analysis ; Humans ; Male ; Female ; Adult ; Immunoassay/methods

Machine learning-guided Orbitrap-HRAMS-based metabolomic fingerprinting for geographical origin, variety and tissue specific authentication, and adulteration detection of turmeric and ashwagandha.

Autoren: Ratnasekhar CH Rai AK Rakwal P et al.

Quelle: Food chemistry [Food Chem] 2025 Aug 01; Vol. 482, pp. 144078. Date of Electronic Publication: 2025 Mar 28.

Publikationsart: Journal Article; Evaluation Study

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Machine Learning* , Metabolomics*/methods , Curcuma*/metabolism , Plant Extracts*/metabolism , Liquid Chromatography-Mass Spectrometry*/methods , Drug Contamination*/prevention & control , Withania*/metabolism, Metabolome ; Peptide Mapping ; Counterfeit Drugs ; Drug Labeling ; Quality Control ; Machine Learning Algorithms ; Food Safety/methods ; Computer Simulation

LC-MS/MS quantification of omadacycline in human plasma for therapeutic drug monitoring: method development and clinical application.

Autoren: Wang Y Diao Z Qu Y et al.

Quelle: Scientific reports [Sci Rep] 2025 Jul 29; Vol. 15 (1), pp. 27728. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Evaluation Study; Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Drug Monitoring*/methods , Liquid Chromatography-Mass Spectrometry*/methods , Tetracyclines*/blood , Tetracyclines*/pharmacokinetics , Anti-Bacterial Agents*/blood , Anti-Bacterial Agents*/pharmacokinetics , Tandem Mass Spectrometry*/methods, Sensitivity and Specificity ; Calibration ; Reproducibility of Results ; Respiratory Tract Infections/blood ; Respiratory Tract Infections/drug therapy ; Linear Models ; Humans ; Male ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Endocannabinoids/blood ; Microbial Sensitivity Tests

Temporal Dynamics and Intermediate Product Formation in DOM Phototransformation Revealed by Liquid Chromatography Ultrahigh-Resolution Mass Spectrometry.

Autoren: Herzsprung P Sobolev A von Tümpling W et al.

Quelle: Environmental science & technology [Environ Sci Technol] 2025 Jul 15; Vol. 59 (27), pp. 13787-13797. Date of Electronic Publication: 2025 Jun 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE

MeSH-Schlagworte: Wastewater* , Liquid Chromatography-Mass Spectrometry*

"UPLC-Q-Exactive-Orbitrap-MS-network pharmacology-experimental verification" integrated strategy to explore substance basis of Coreopsis tinctoria flavonoids for liver protection.

Autoren: Du J Zhou X Chen X

Quelle: Fitoterapia [Fitoterapia] 2025 Jul; Vol. 184, pp. 106640. Date of Electronic Publication: 2025 May 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

MeSH-Schlagworte: Coreopsis*/chemistry , Plant Extracts*/chemistry , Plant Extracts*/isolation & purification , Plant Extracts*/pharmacology , Flavonoids*/chemistry , Flavonoids*/isolation & purification , Flavonoids*/pharmacology , Protective Agents*/chemistry , Protective Agents*/isolation & purification , Protective Agents*/pharmacology , Liquid Chromatography-Mass Spectrometry*/methods , Chemical and Drug Induced Liver Injury*/drug therapy , Chemical and Drug Induced Liver Injury*/prevention & control, Network Pharmacology ; Liver/cytology ; Liver/drug effects ; Acetaminophen/toxicity ; Freeze Drying ; Hepatocytes ; Cell Line ; Animals ; Rats ; Molecular Docking Simulation ; Molecular Structure ; Humans

LC-MS/MS determination of trazodone in human plasma and its pharmacokinetic study in healthy Chinese.

Autoren: Luo K Liu D Zhang S et al.

Quelle: Bioanalysis [Bioanalysis] 2025 May; Vol. 17 (10), pp. 661-669. Date of Electronic Publication: 2025 May 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101512484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-6199 (Electronic) Linking ISSN: 17576180 NLM ISO Abbreviation: Bioanalysis Subsets: MEDLINE

MeSH-Schlagworte: Liquid Chromatography-Mass Spectrometry* , Trazodone*/blood , Trazodone*/pharmacokinetics, Adult ; Female ; Humans ; Male ; Young Adult ; China ; Healthy Volunteers ; East Asian People

Quantitation of antibiotics in fresh fermentation medium by hydrophilic interaction chromatography mass spectrometry.

Autoren: Marcon N Rüdt M Klein J et al.

Quelle: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2025 Apr; Vol. 417 (9), pp. 1927-1934. Date of Electronic Publication: 2025 Feb 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/analysis , Liquid Chromatography-Mass Spectrometry*/methods , Industrial Microbiology*/methods, Fermentation ; Hydrophobic and Hydrophilic Interactions ; Culture Media/chemistry ; Bioreactors

An LCMS/MS method for the simultaneous determination of ten antimicrobials and its application in critically ill patients.

Autoren: Liu T Chen X Zhang G et al.

Quelle: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Jan 01; Vol. 252, pp. 116489. Date of Electronic Publication: 2024 Sep 30.

Publikationsart: Evaluation Study; Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/pharmacokinetics , Antifungal Agents*/pharmacokinetics , Liquid Chromatography-Mass Spectrometry*/methods , Liquid Chromatography-Mass Spectrometry*/statistics & numerical data , Drug Monitoring*/methods , Drug Monitoring*/statistics & numerical data , Tandem Mass Spectrometry*/methods , Microbial Sensitivity Tests*/methods, Critical Illness ; Methanol ; Isotopes ; Sensitivity and Specificity ; Linear Models ; Humans ; Male ; Female ; Aged ; Aged, 80 and over ; Critical Care/methods

[Determination of three metabolites of thromboxane A 2 and 8-iso-prostaglandin F 2α in urine by ultra performance liquid chromatography-tandem mass spectrometry].

Autoren: Liu SJ Zhao FR Zhang YL et al.

Quelle: Se pu = Chinese journal of chromatography [Se Pu] 2025 Feb; Vol. 43 (2), pp. 148-154.

Publikationsart: English Abstract; Journal Article

Info zur Zeitschrift: Publisher: Hua xue za zhi she Country of Publication: China NLM ID: 9424804 Publication Model: Print Cited Medium: Internet ISSN: 1872-2059 (Electronic) Linking ISSN: 10008713 NLM ISO Abbreviation: Se Pu Subsets: MEDLINE

MeSH-Schlagworte: Liquid Chromatography-Mass Spectrometry* , Thromboxane A2*/analogs & derivatives , Thromboxane A2*/analysis , Urinalysis*/instrumentation , Urinalysis*/methods , Dinoprost*/analogs & derivatives , Dinoprost*/analysis, Ischemic Stroke/diagnosis ; Ischemic Stroke/urine ; Limit of Detection ; Humans

Distinguishing Artifactual Fatty Acid Dimers from Fatty Acid Esters of Hydroxy Fatty Acids in Untargeted LC-MS Pipelines.

Autoren: Nelson AB Queathem ED Puchalska P

Quelle: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2855, pp. 67-84.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Esters*/analysis , Esters*/chemistry , Esters*/metabolism , Fatty Acids*/analysis , Fatty Acids*/metabolism , Fatty Acids*/chemistry , Liquid Chromatography-Mass Spectrometry*/methods , Metabolomics*/methods, Humans ; Artifacts ; Dimerization ; Hydrophobic and Hydrophilic Interactions ; Hydroxy Acids/analysis ; Hydroxy Acids/metabolism ; Hydroxy Acids/chemistry

Stable Isotope Tracing Experiments Using LC-MS.

Autoren: Zaal EA Jansen JWA Berkers CR

Quelle: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2855, pp. 103-116.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Isotope Labeling*/methods , Liquid Chromatography-Mass Spectrometry*/methods , Metabolomics*/methods, Animals ; Humans

Development and Validation of an Analytical Method to Identify and Quantitate Novel Modafinil Analogs in Products Marketed as Dietary Supplements.

Autoren: Bakota EL Nandrea JM

Quelle: Journal of dietary supplements [J Diet Suppl] 2025; Vol. 22 (2), pp. 329-344. Date of Electronic Publication: 2024 Oct 28.

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101249830 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-022X (Electronic) Linking ISSN: 19390211 NLM ISO Abbreviation: J Diet Suppl Subsets: MEDLINE

MeSH-Schlagworte: Illicit Drugs*/analysis , Modafinil*/analogs & derivatives , Modafinil*/analysis , Liquid Chromatography-Mass Spectrometry*/methods , Dietary Supplements*/analysis , Central Nervous System Stimulants*/analysis, Reproducibility of Results ; Hydroxamic Acids

A novel application of LC-MS/MS accurately quantifies the labile redox pools of cellular coenzymes Q 9 and Q 10 .

Autoren: Jain A Li VW Salem J et al.

Quelle: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 01; Vol. 240, pp. 96-107. Date of Electronic Publication: 2025 Aug 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

MeSH-Schlagworte: Ubiquinone*/analogs & derivatives , Ubiquinone*/metabolism , Ubiquinone*/analysis , Tandem Mass Spectrometry*/methods, Animals ; Oxidation-Reduction ; Mice ; Humans ; Chromatography, Liquid/methods ; Mitochondria/metabolism ; Macrophages/metabolism ; Macrophages/drug effects ; Liquid Chromatography-Mass Spectrometry

Host cell protein quantitation by LC-MS. Experimental demonstration, qualification, and comparison of methods in USP 1132.1.

Autoren: Chrone VG Blaszczyk AJ Zhang DH et al.

Quelle: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Nov 15; Vol. 265, pp. 117051. Date of Electronic Publication: 2025 Jul 03.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH-Schlagworte: Drug Contamination*/prevention & control , Mass Spectrometry*/methods , Proteins*/analysis , Biological Products*/analysis, Animals ; Cricetulus ; CHO Cells ; Chromatography, Liquid/methods ; Antibodies, Monoclonal/analysis ; Antibodies, Monoclonal/chemistry ; Reproducibility of Results ; Pharmacopoeias as Topic ; Tandem Mass Spectrometry/methods ; Cricetinae ; Enzyme-Linked Immunosorbent Assay/methods ; Liquid Chromatography-Mass Spectrometry

Residue depletion study and withdrawal period in milk for intramuscular gentamicin in dairy cows using LC-MS/MS.

Autoren: Kim D Nam SM Moon H et al.

Quelle: Journal of veterinary science [J Vet Sci] 2025 Nov; Vol. 26 (6), pp. e89.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Korean Society of Veterinary Science Country of Publication: Korea (South) NLM ID: 100964185 Publication Model: Print Cited Medium: Internet ISSN: 1976-555X (Electronic) Linking ISSN: 1229845X NLM ISO Abbreviation: J Vet Sci Subsets: MEDLINE

MeSH-Schlagworte: Milk*/chemistry , Tandem Mass Spectrometry*/veterinary , Tandem Mass Spectrometry*/methods , Gentamicins*/administration & dosage , Gentamicins*/analysis , Gentamicins*/chemistry , Drug Residues*/analysis , Anti-Bacterial Agents*/analysis , Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/chemistry, Animals ; Cattle ; Female ; Chromatography, Liquid/veterinary ; Chromatography, Liquid/methods ; Injections, Intramuscular/veterinary ; Liquid Chromatography-Mass Spectrometry

Screening and Validation Serum Potential Biomarkers for Intrahepatic Cholestasis of Pregnancy Comparison to Healthy Controls by ¹ H-NMR and UPLC-MS/MS.

Autoren: Deng Y Wang J Zhan D et al.

Quelle: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Nov; Vol. 39 (11), pp. e70234.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods , Biomarkers*/blood , Cholestasis, Intrahepatic*/blood , Cholestasis, Intrahepatic*/diagnosis , Pregnancy Complications*/blood , Pregnancy Complications*/diagnosis , Proton Magnetic Resonance Spectroscopy*/methods, Humans ; Female ; Pregnancy ; Adult ; Chromatography, High Pressure Liquid/methods ; Choline/blood ; Case-Control Studies ; Reproducibility of Results ; Metabolomics/methods ; Young Adult ; Liquid Chromatography-Mass Spectrometry ; Sarcosine/analogs & derivatives

SCR Disease Name: Intrahepatic Cholestasis of Pregnancy

Elucidating the clay-mediated fixation mechanism of humic acids in composting systems using LC-MS and spectroscopic techniques.

Autoren: Shen B Zhang X Tao W et al.

Quelle: Environmental research [Environ Res] 2025 Oct 15; Vol. 283, pp. 122106. Date of Electronic Publication: 2025 Jun 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE

MeSH-Schlagworte: Humic Substances*/analysis , Composting*/methods , Aluminum Silicates*/chemistry , Soil*/chemistry, Clay ; Mass Spectrometry ; Chromatography, Liquid ; Spectrum Analysis ; Liquid Chromatography-Mass Spectrometry