Výsledky vyhľadávania - "Lignans"

New tetrahydrobenzocyclooctabenzofuranone and dibenzocyclooctadiene lignans from Kadsura jaonica.

Autori: Su Y Shen J Yao S a ďalší

Zdroj: Fitoterapia [Fitoterapia] 2025 Oct; Vol. 186, pp. 106858. Date of Electronic Publication: 2025 Aug 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/isolation & purification , Lignans*/pharmacology , Cyclooctanes*/isolation & purification , Cyclooctanes*/pharmacology , Cyclooctanes*/chemistry , Kadsura*/chemistry , Antineoplastic Agents, Phytogenic*/isolation & purification , Antineoplastic Agents, Phytogenic*/pharmacology, Humans ; Molecular Structure ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; HCT116 Cells ; China

Discovery of lignans as the effective inhibitors of CES1A alleviate lipid droplets formation.

Autori: Mu J Chen SS Li SQ a ďalší

Zdroj: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2472817. Date of Electronic Publication: 2025 Apr 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/pharmacology , Lignans*/chemistry , Lignans*/chemical synthesis , Lipid Droplets*/metabolism , Lipid Droplets*/drug effects , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis , Drug Discovery* , Carboxylesterase*/antagonists & inhibitors , Carboxylesterase*/metabolism , Carboxylic Ester Hydrolases*/antagonists & inhibitors , Carboxylic Ester Hydrolases*/metabolism, Humans ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Hep G2 Cells

Isolation, structural characterization, anti-tumor activity, and mechanisms of novel compounds from the roots of Aconitum pendulum Busch.

Autori: Li X Li J Liu H a ďalší

Zdroj: Fitoterapia [Fitoterapia] 2025 Dec; Vol. 187, pp. 106923. Date of Electronic Publication: 2025 Oct 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aconitum*/chemistry , Antineoplastic Agents, Phytogenic*/isolation & purification , Antineoplastic Agents, Phytogenic*/pharmacology , Alkaloids*/isolation & purification , Alkaloids*/pharmacology , Lignans*/isolation & purification , Lignans*/pharmacology, Plant Roots/chemistry ; Humans ; Molecular Structure ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Apoptosis/drug effects ; Cell Line, Tumor ; Hep G2 Cells ; NF-kappa B/metabolism ; Cell Movement/drug effects ; China

Flax Lignans modulate the digestion and absorption of α-linolenic acid in sunflower phospholipid-stabilized nanoemulsions: In vitro digestion simulation and in vivo studies in mice.

Autori: Wang L Yu X Cheng C a ďalší

Zdroj: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Nov; Vol. 220, pp. 117049. Date of Electronic Publication: 2025 Jul 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

Výrazy zo slovníka MeSH: alpha-Linolenic Acid*/pharmacokinetics , alpha-Linolenic Acid*/metabolism , alpha-Linolenic Acid*/blood , Lignans*/pharmacology , Lignans*/chemistry , Flax*/chemistry , Digestion*/drug effects , Phospholipids*/chemistry , Intestinal Absorption*/drug effects , Helianthus*/chemistry, Emulsions ; Animals ; Mice ; Male ; Biological Availability

Xuetonlignans E-K, unusual spirobenzofuranoid dibenzocyclooctadiene lignans with hepatoprotective activity from the roots of Kadsura heteroclita.

Autori: Su W Zhou X Yuan H a ďalší

Zdroj: Phytochemistry [Phytochemistry] 2025 Nov; Vol. 239, pp. 114594. Date of Electronic Publication: 2025 Jun 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

Výrazy zo slovníka MeSH: Plant Roots*/chemistry , Lignans*/chemistry , Lignans*/pharmacology , Lignans*/isolation & purification , Kadsura*/chemistry , Cyclooctanes*/chemistry , Cyclooctanes*/pharmacology , Cyclooctanes*/isolation & purification , Protective Agents*/pharmacology , Protective Agents*/chemistry , Protective Agents*/isolation & purification , Spiro Compounds*/chemistry , Spiro Compounds*/pharmacology , Spiro Compounds*/isolation & purification, Humans ; Hep G2 Cells ; Molecular Structure ; Hydrogen Peroxide/pharmacology ; Crystallography, X-Ray ; Cell Survival/drug effects ; Molecular Conformation

Pharmacological Potential and Molecular Targets of Tetrahydrofurofuranoid Lignans From Magnoliae Flos .

Autori: Yi X Xiao Z Chen J a ďalší

Zdroj: Drug design, development and therapy [Drug Des Devel Ther] 2025 Oct 03; Vol. 19, pp. 9011-9027. Date of Electronic Publication: 2025 Oct 03 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/pharmacology , Lignans*/chemistry , Lignans*/isolation & purification , Magnolia*/chemistry , Plant Extracts*/chemistry , Plant Extracts*/pharmacology , Plant Extracts*/isolation & purification, Humans ; Flowers/chemistry ; Animals ; Inflammation/drug therapy

New lignans from Phyllanthodendron dunnianum .

Autori: Xu L Tan JB Zheng YT a ďalší

Zdroj: Natural product research [Nat Prod Res] 2025 Oct; Vol. 39 (20), pp. 5823-5831. Date of Electronic Publication: 2024 May 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/chemistry , Lignans*/pharmacology , Lignans*/isolation & purification , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/isolation & purification, Microbial Sensitivity Tests ; Molecular Structure ; Staphylococcus aureus/drug effects ; Enterococcus faecalis/drug effects ; Escherichia coli/drug effects ; Plant Leaves/chemistry ; Pseudomonas aeruginosa/drug effects ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Circular Dichroism ; Magnetic Resonance Spectroscopy ; Plant Extracts/chemistry

Syringaresinol: Exploring Its Natural Sources, Bioactivity, and Health Benefits.

Autori: Mssillou I Bakour M Amrati FE a ďalší

Zdroj: Chemistry & biodiversity [Chem Biodivers] 2025 Oct; Vol. 22 (10), pp. e00352. Date of Electronic Publication: 2025 Jun 03.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/isolation & purification , Biological Products*/chemistry , Biological Products*/pharmacology , Biological Products*/isolation & purification , Furans*/chemistry , Furans*/pharmacology , Furans*/isolation & purification , Lignans*/chemistry , Lignans*/pharmacology , Lignans*/isolation & purification, Animals ; Humans ; Antineoplastic Agents, Phytogenic/pharmacology ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cyclooxygenase 2 Inhibitors

Discovery of lignans from leaves of Phyllanthus emblica L. and their antioxidant-antiinflammatory activity.

Autori: Luo D Yang M Li YM a ďalší

Zdroj: Fitoterapia [Fitoterapia] 2025 Oct; Vol. 186, pp. 106831. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/isolation & purification , Lignans*/pharmacology , Anti-Inflammatory Agents*/isolation & purification , Anti-Inflammatory Agents*/pharmacology , Antioxidants*/isolation & purification , Antioxidants*/pharmacology , Phyllanthus emblica*/chemistry, Mice ; RAW 264.7 Cells ; Plant Leaves/chemistry ; Animals ; Nitric Oxide/metabolism ; Molecular Structure ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; China ; Plant Extracts/chemistry ; Macrophages/drug effects

New nor -lignans from the leaves of styrax annamensis guillaumin.

Autori: Tra NT Van Tuyen N Thi Thu Ha N a ďalší

Zdroj: Natural product research [Nat Prod Res] 2025 Oct; Vol. 39 (20), pp. 5807-5813. Date of Electronic Publication: 2024 May 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Plant Leaves*/chemistry , Lignans*/chemistry , Lignans*/isolation & purification , Lignans*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/isolation & purification, Humans ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Cholinesterase Inhibitors/isolation & purification ; Molecular Structure ; Cell Line, Tumor ; MCF-7 Cells ; Inhibitory Concentration 50 ; Drug Screening Assays, Antitumor ; Hep G2 Cells

Design, synthesis and biological evaluation of magnolol-sulforaphane hybrid analogues as potential therapeutics of triple-negative breast cancer.

Autori: Liang Y Tai X Wang F a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118136. Date of Electronic Publication: 2025 Sep 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Isothiocyanates*/chemistry , Isothiocyanates*/pharmacology , Isothiocyanates*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Lignans*/chemistry , Lignans*/pharmacology , Lignans*/chemical synthesis , Biphenyl Compounds*/chemistry , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/chemical synthesis , Drug Design*, Humans ; Cell Proliferation/drug effects ; Sulfoxides/chemistry ; Sulfoxides/pharmacology ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Animals ; Female ; Mice ; Molecular Structure ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects

Design, synthesis, and biological evaluation of arctigenin derivatives as novel GPX4 inhibitors in colorectal cancer cells.

Autori: Wang YX Zhu L Zhang L a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118181. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/pharmacology , Lignans*/chemistry , Lignans*/chemical synthesis , Furans*/pharmacology , Furans*/chemistry , Furans*/chemical synthesis , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/metabolism , Drug Design* , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Phospholipid Hydroperoxide Glutathione Peroxidase*/antagonists & inhibitors , Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemical synthesis , Enzyme Inhibitors*/chemistry, Humans ; Structure-Activity Relationship ; Molecular Structure ; Drug Screening Assays, Antitumor ; HCT116 Cells ; Dose-Response Relationship, Drug ; Ferroptosis/drug effects ; Cell Proliferation/drug effects ; Reactive Oxygen Species/metabolism ; Molecular Docking Simulation

Honolignols A-C, Three Racemic Forms of Honokiol-Derived Dimeric Neolignans from Magnolia Officinalis Var. Biloba .

Autori: Huang WM Ying P Gong HF a ďalší

Zdroj: The Journal of organic chemistry [J Org Chem] 2025 Dec 05; Vol. 90 (48), pp. 17034-17042. Date of Electronic Publication: 2025 Nov 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lignans*/chemistry , Lignans*/isolation & purification , Lignans*/pharmacology , Magnolia*/chemistry , Biphenyl Compounds*/chemistry , Biphenyl Compounds*/isolation & purification, Stereoisomerism ; Dimerization ; Molecular Structure ; Humans ; Allyl Compounds ; Phenols

Sesamin alleviates drug-induced hepatotoxicity via autophagy enhancement and ferroptosis inhibition.

Autori: Ren J Wang Z Zhang Y a ďalší

Zdroj: Redox report : communications in free radical research [Redox Rep] 2025 Dec; Vol. 30 (1), pp. 2588863. Date of Electronic Publication: 2025 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-2928 (Electronic) Linking ISSN: 13510002 NLM ISO Abbreviation: Redox Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Autophagy*/drug effects , Lignans*/pharmacology , Lignans*/therapeutic use , Ferroptosis*/drug effects , Dioxoles*/pharmacology , Dioxoles*/therapeutic use , Chemical and Drug Induced Liver Injury*/drug therapy , Chemical and Drug Induced Liver Injury*/metabolism, Animals ; Mice ; Humans ; Mice, Inbred C57BL ; Acetaminophen/toxicity ; Acetaminophen/adverse effects ; Male ; Hep G2 Cells ; Forkhead Box Protein O1/metabolism ; Forkhead Box Protein O1/genetics ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Signal Transduction/drug effects ; Liver/drug effects ; Liver/metabolism

Natural anti-neuroinflammatory inhibitors from Aglaia odorata .

Autori: Liu XY Zhang JJ Yin QQ a ďalší

Zdroj: Journal of Asian natural products research [J Asian Nat Prod Res] 2025 Dec; Vol. 27 (12), pp. 1799-1806. Date of Electronic Publication: 2025 Apr 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100888334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2213 (Electronic) Linking ISSN: 10286020 NLM ISO Abbreviation: J Asian Nat Prod Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/isolation & purification , Aglaia*/chemistry , Lignans*/pharmacology , Lignans*/chemistry , Lignans*/isolation & purification, Nitric Oxide/biosynthesis ; Lipopolysaccharides/pharmacology ; Microglia/drug effects ; Molecular Structure ; Animals ; Mice

Isolation and bioactivity evaluation of ten novel norlignans and additional neuroprotective compounds from Curculigo gracilis.

Autori: Ma W Wang XR Niu WJ a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109189. Date of Electronic Publication: 2025 Nov 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/isolation & purification , Neuroprotective Agents*/chemistry , Lignans*/pharmacology , Lignans*/isolation & purification , Lignans*/chemistry , Curculigo*/chemistry, Humans ; Structure-Activity Relationship ; Cell Survival/drug effects ; Molecular Structure ; Oxidative Stress/drug effects ; Dose-Response Relationship, Drug ; Cell Line, Tumor ; Glutamic Acid/pharmacology

Wuweizisu B for cancer treatment from multitarget mechanisms to precision delivery strategies (Review).

Autori: Zhong L Li Y Liu C a ďalší

Zdroj: International journal of molecular medicine [Int J Mol Med] 2025 Dec; Vol. 56 (6). Date of Electronic Publication: 2025 Oct 17.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/drug therapy , Neoplasms*/metabolism , Neoplasms*/pathology , Lignans*/therapeutic use , Lignans*/pharmacology , Lignans*/chemistry , Drug Delivery Systems*/methods , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/pharmacology, Humans ; Animals ; Apoptosis/drug effects

Oral supplementation with sesaminol, a sesame-related lignan, ameliorates ethanol-induced dysbiosis of the gut microbiota and increases the gut luminal short-chain fatty acid concentrations of mice.

Autori: Oikawa D Ohira H Aoki Y a ďalší

Zdroj: The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Dec; Vol. 146, pp. 110052. Date of Electronic Publication: 2025 Aug 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Gastrointestinal Microbiome*/drug effects , Dioxoles*/pharmacology , Dioxoles*/administration & dosage , Dysbiosis*/chemically induced , Dysbiosis*/drug therapy , Ethanol*/adverse effects , Fatty Acids, Volatile*/metabolism , Lignans*/pharmacology , Lignans*/administration & dosage, Animals ; Male ; Feces/microbiology ; Feces/chemistry ; Mice ; Administration, Oral ; Dietary Supplements ; Sesamum/chemistry ; Mice, Inbred C57BL ; Furans

Sesamin protects against Acetaminophen-induced nephrotoxicity by suppressing HMOX1-mediated apoptosis and ferroptosis.

Autori: Zhu S Ren J Zhang Y a ďalší

Zdroj: Redox report : communications in free radical research [Redox Rep] 2025 Dec; Vol. 30 (1), pp. 2529695. Date of Electronic Publication: 2025 Jul 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-2928 (Electronic) Linking ISSN: 13510002 NLM ISO Abbreviation: Redox Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dioxoles*/chemistry , Dioxoles*/pharmacology , Lignans*/chemistry , Lignans*/pharmacology , Apoptosis*/drug effects , Ferroptosis*/drug effects , Heme Oxygenase-1*/chemistry , Heme Oxygenase-1*/genetics , Heme Oxygenase-1*/metabolism , Kidney Diseases*/chemically induced , Kidney Diseases*/enzymology , Kidney Diseases*/genetics , Kidney Diseases*/pathology, Humans ; Male ; Animals ; Mice ; Mice, Inbred C57BL ; Cell Line ; Acetaminophen/pharmacology ; Oxidative Stress/drug effects ; Network Pharmacology/methods ; Protein Structure, Tertiary ; Molecular Docking Simulation ; Membrane Proteins

Mechanistic insights into Schisandrin C as the active anti-renal fibrosis ingredient of Schisandra chinensis: a network pharmacology analysis and transcriptomics integrated experimental verification.

Autori: Yang X Qiaolongbatu X Shen R a ďalší

Zdroj: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Dec; Vol. 398 (12), pp. 17503-17523. Date of Electronic Publication: 2025 Jun 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Schisandra*/chemistry , Lignans*/pharmacology , Lignans*/therapeutic use , Polycyclic Compounds*/pharmacology , Polycyclic Compounds*/therapeutic use , Kidney*/drug effects , Kidney*/pathology , Kidney*/metabolism , Kidney Diseases*/drug therapy , Kidney Diseases*/pathology , Kidney Diseases*/genetics , Antifibrotic Agents*/pharmacology, Animals ; Zebrafish ; Fibrosis ; Network Pharmacology ; Cyclooctanes/pharmacology ; Cyclooctanes/therapeutic use ; Transcriptome/drug effects ; Humans ; Molecular Docking Simulation ; Signal Transduction/drug effects ; Disease Models, Animal