Výsledky vyhľadávania - "Leukocytes"

Selective Blockade of Two Aquaporin Channels, AQP3 and AQP9, Impairs Human Leukocyte Migration.

Autori: Garra S Mejlstrup Hymøller C Di Molfetta D a ďalší

Zdroj: Cells [Cells] 2025 Jun 11; Vol. 14 (12). Date of Electronic Publication: 2025 Jun 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aquaporin 3*/antagonists & inhibitors , Aquaporin 3*/metabolism , Aquaporin 3*/genetics , Cell Movement*/drug effects , Aquaporins*/antagonists & inhibitors , Aquaporins*/metabolism , Aquaporins*/genetics , Leukocytes*/metabolism , Leukocytes*/drug effects, Humans ; Phagocytosis/drug effects ; Klebsiella pneumoniae/drug effects ; Lipopolysaccharides/pharmacology ; Neutrophils/metabolism ; Neutrophils/drug effects ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/drug effects

Assessing the effects of ex vivo hormonal exposure on oxidative responses in equine leukocytes: A preliminary study.

Autori: Vaughn SA Berghaus LJ Hart KA

Zdroj: Veterinary immunology and immunopathology [Vet Immunol Immunopathol] 2024 Oct; Vol. 276, pp. 110827. Date of Electronic Publication: 2024 Sep 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Scientific Country of Publication: Netherlands NLM ID: 8002006 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2534 (Electronic) Linking ISSN: 01652427 NLM ISO Abbreviation: Vet Immunol Immunopathol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Adrenocorticotropic Hormone*/pharmacology , Adrenocorticotropic Hormone*/blood , Reactive Oxygen Species*/metabolism , alpha-MSH* , Leptin*/blood , Insulin*/blood , Insulin*/metabolism , Leukocytes*/drug effects , Leukocytes*/metabolism , Leukocytes*/immunology, Animals ; Horses/immunology ; Male ; Oxidative Stress/drug effects ; Female ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Neutrophils/drug effects ; Neutrophils/immunology ; Neutrophils/metabolism

Effect of bisphenol-A and bisphenol-S on functional parameters of human leukocytes.

Autori: Girón-Pérez MI Ventura-Ramón GH Covantes-Rosales CE a ďalší

Zdroj: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2025 Oct; Vol. 47 (5), pp. 621-630. Date of Electronic Publication: 2025 Aug 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2513 (Electronic) Linking ISSN: 08923973 NLM ISO Abbreviation: Immunopharmacol Immunotoxicol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Phenols*/toxicity , Phenols*/pharmacology , Benzhydryl Compounds*/toxicity , Benzhydryl Compounds*/pharmacology , Leukocytes*/drug effects , Leukocytes*/metabolism , Leukocytes*/immunology , Sulfones*/toxicity , Sulfones*/pharmacology, Humans ; Membrane Potential, Mitochondrial/drug effects ; Membrane Potential, Mitochondrial/immunology ; Reactive Oxygen Species/metabolism ; Apoptosis/drug effects ; Apoptosis/immunology ; Calcium/metabolism ; Cellular Senescence/drug effects ; Cellular Senescence/immunology ; Adult ; Male ; Bisphenol A Compounds ; Bisphenol S Compounds

Time-Dependent EDTA Effect on Leukocyte Differential Count and Morphology Compared to Blood Smear Made by Direct Finger Prick.

Autori: Irding A Landgren F Aardal E

Zdroj: International journal of laboratory hematology [Int J Lab Hematol] 2025 Oct; Vol. 47 (5), pp. 826-831. Date of Electronic Publication: 2025 May 16.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 101300213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-553X (Electronic) Linking ISSN: 17515521 NLM ISO Abbreviation: Int J Lab Hematol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Edetic Acid*/pharmacology , Leukocytes*/cytology , Leukocytes*/drug effects , Blood Specimen Collection*/methods, Humans ; Leukocyte Count/methods ; Time Factors ; Male ; Female

Autophagy and mitophagy in circulating immune cells of women with polycystic ovary syndrome: A cardiovascular perspective.

Autori: Pelechá-Salvador M Márquez-Arrico CF Fernández-Reyes M a ďalší

Zdroj: Free radical biology & medicine [Free Radic Biol Med] 2025 Dec 16; Vol. 241, pp. 161-170. Date of Electronic Publication: 2025 Sep 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Polycystic Ovary Syndrome*/pathology , Polycystic Ovary Syndrome*/immunology , Polycystic Ovary Syndrome*/blood , Polycystic Ovary Syndrome*/metabolism , Mitophagy* , Autophagy* , Leukocytes, Mononuclear*/pathology , Leukocytes, Mononuclear*/metabolism , Leukocytes, Mononuclear*/immunology , Cardiovascular Diseases*/pathology, Humans ; Female ; Adult ; Oxidative Stress ; Cross-Sectional Studies ; Biomarkers/blood ; Young Adult ; Membrane Potential, Mitochondrial ; Endothelial Cells/pathology ; Endothelial Cells/metabolism ; Case-Control Studies ; Peroxidase/blood ; Inflammation/pathology ; Neutrophils/pathology ; Neutrophils/metabolism ; Neutrophils/immunology

Human cord blood mononuclear cells alleviate intestinal inflammation and barrier dysfunction by regulating gut metabolites and Th17/Treg balance.

Autori: Lyu L Ma Y Sun X a ďalší

Zdroj: Molecular immunology [Mol Immunol] 2025 Dec; Vol. 188, pp. 179-191. Date of Electronic Publication: 2025 Nov 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 7905289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9142 (Electronic) Linking ISSN: 01615890 NLM ISO Abbreviation: Mol Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Th17 Cells*/immunology , T-Lymphocytes, Regulatory*/immunology , Colitis*/immunology , Colitis*/therapy , Colitis*/chemically induced , Colitis*/metabolism , Fetal Blood*/cytology , Leukocytes, Mononuclear*/immunology , Leukocytes, Mononuclear*/transplantation , Inflammation*/immunology , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/immunology, Animals ; Humans ; Mice, Inbred C57BL ; Male ; Mice ; Dextran Sulfate ; Inflammatory Bowel Diseases/immunology ; Inflammatory Bowel Diseases/therapy

The effect of increasing levels of hyperthermia on autophagy and cellular stress in peripheral blood mononuclear cells from young adults.

Autori: McCormick JJ King KE Hutchins KP a ďalší

Zdroj: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2025 Dec 01; Vol. 329 (6), pp. R987-R994. Date of Electronic Publication: 2025 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1490 (Electronic) Linking ISSN: 03636119 NLM ISO Abbreviation: Am J Physiol Regul Integr Comp Physiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Autophagy*/physiology , Leukocytes, Mononuclear*/metabolism , Leukocytes, Mononuclear*/pathology , Heat-Shock Response* , Hyperthermia*/physiopathology , Hyperthermia*/blood , Hyperthermia*/metabolism , Hyperthermia*/pathology, Humans ; Female ; Young Adult ; Male ; Adult ; Apoptosis ; Hot Temperature

Salmonella typhimurium infection increased the necrosis of diazoxon-exposed mononuclear cells.

Autori: Girón-Pérez DA Ley-Arteaga LV Covantes-Rosales CE a ďalší

Zdroj: International journal of environmental health research [Int J Environ Health Res] 2025 Dec; Vol. 35 (12), pp. 4051-4060. Date of Electronic Publication: 2025 Jun 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9106628 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1619 (Electronic) Linking ISSN: 09603123 NLM ISO Abbreviation: Int J Environ Health Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Salmonella typhimurium*/physiology , Leukocytes, Mononuclear*/drug effects , Leukocytes, Mononuclear*/microbiology , Salmonella Infections*/microbiology, Humans ; Necrosis/chemically induced ; Apoptosis/drug effects

Impact of pre- and post-thaw processing on recovery and fitness of cord blood mononuclear cells as starting material for cell therapy.

Autori: Coutu-Godbout L Perreault J Fournier D a ďalší

Zdroj: Cytotherapy [Cytotherapy] 2025 Dec; Vol. 27 (12), pp. 1463-1470. Date of Electronic Publication: 2025 Sep 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 100895309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2566 (Electronic) Linking ISSN: 14653249 NLM ISO Abbreviation: Cytotherapy Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cryopreservation*/methods , Leukocytes, Mononuclear*/cytology , Leukocytes, Mononuclear*/metabolism , Fetal Blood*/cytology , Cell- and Tissue-Based Therapy*/methods, Humans ; Cell Proliferation ; Cell Separation/methods ; Apoptosis

Mechanisms That Prevent Vascular Leakage During Leukocyte Extravasation.

Autori: de Haan SJ van Buul JD

Zdroj: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2025 Dec; Vol. 241 (12), pp. e70126.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print Cited Medium: Internet ISSN: 1748-1716 (Electronic) Linking ISSN: 17481708 NLM ISO Abbreviation: Acta Physiol (Oxf) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leukocytes*/physiology , Leukocytes*/metabolism , Transendothelial and Transepithelial Migration*/physiology , Inflammation*/physiopathology , Inflammation*/metabolism , Capillary Permeability*/physiology, Humans ; Animals ; Endothelium, Vascular

Elevated TFEB expression with limited activation in peripheral blood mononuclear cells reflects altered lysosomal enzyme dynamics in Parkinson's disease.

Autori: Mizutani Y Nawashiro K Ito S a ďalší

Zdroj: Neurobiology of disease [Neurobiol Dis] 2025 Dec; Vol. 217, pp. 107151. Date of Electronic Publication: 2025 Oct 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/metabolism , Basic Helix-Loop-Helix Leucine Zipper Transcription Factors*/blood , Leukocytes, Mononuclear*/metabolism , Leukocytes, Mononuclear*/enzymology , Parkinson Disease*/enzymology , Parkinson Disease*/blood , Lysosomes*/enzymology , Lysosomes*/metabolism, Humans ; Male ; Female ; Aged ; Middle Aged

Cytotoxic and immunotoxic profile of HgCl 2 involves alterations in purinergic signaling through the P2X7/NLRP3/CASP-1/IL-1β pathway: An in vitro study using human blood immune cells.

Autori: Schott M Assmann CE Rambo BVC a ďalší

Zdroj: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2025 Dec; Vol. 109, pp. 106131. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 8712158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3177 (Electronic) Linking ISSN: 08872333 NLM ISO Abbreviation: Toxicol In Vitro Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leukocytes, Mononuclear*/drug effects , Leukocytes, Mononuclear*/metabolism , Mercuric Chloride*/toxicity, Humans ; Receptors, Purinergic P2X7/metabolism ; Receptors, Purinergic P2X7/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Signal Transduction/drug effects ; Interleukin-1beta/metabolism ; Interleukin-1beta/genetics ; Cell Survival/drug effects ; Apoptosis/drug effects ; Caspase 1/metabolism ; Caspase 1/genetics ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Cells, Cultured ; Nitric Oxide/metabolism

Single-cell sequencing of peripheral blood mononuclear cells reveals immune landscape of monkeypox patients with HIV.

Autori: Liu Y Liu X Wang J a ďalší

Zdroj: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2459136. Date of Electronic Publication: 2025 Feb 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leukocytes, Mononuclear*/immunology , Leukocytes, Mononuclear*/virology , HIV Infections*/immunology , HIV Infections*/complications , HIV Infections*/virology , Mpox, Monkeypox*/immunology , Mpox, Monkeypox*/virology , Mpox, Monkeypox*/complications, Humans ; Single-Cell Analysis ; Male ; Adult ; Female ; Middle Aged ; Monkeypox virus/immunology

Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease.

Autori: Morsy Y Walberg Å Wawrzyniak P a ďalší

Zdroj: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2530157. Date of Electronic Publication: 2025 Jul 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

Výrazy zo slovníka MeSH: Colorectal Neoplasms*/microbiology , Colorectal Neoplasms*/immunology , Colorectal Neoplasms*/blood , Inflammatory Bowel Diseases*/microbiology , Inflammatory Bowel Diseases*/immunology , Inflammatory Bowel Diseases*/blood , Leukocytes, Mononuclear*/microbiology , Leukocytes, Mononuclear*/immunology , Gastrointestinal Microbiome* , Bacteria*/genetics , Bacteria*/classification , Bacteria*/isolation & purification , DNA, Bacterial*/genetics, Humans ; Male ; Female ; Middle Aged ; RNA, Ribosomal, 16S/genetics ; Metagenomics ; Adult ; Bacterial Translocation ; Aged

ADAM8 Destroys the Endothelial Barrier and Promotes Leukocyte Extravasation to Aggravate Hepatic Ischemia-Reperfusion Injury.

Autori: Li J Zhang W Zhang Y a ďalší

Zdroj: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Nov 30; Vol. 39 (22), pp. e71217.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Reperfusion Injury*/metabolism , Reperfusion Injury*/pathology , Liver*/metabolism , Liver*/pathology , ADAM Proteins*/metabolism , ADAM Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Leukocytes*/metabolism , Leukocytes*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Liver Diseases*/metabolism , Liver Diseases*/pathology, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Humans ; Neutrophils/metabolism ; Antigens, CD

Enhancing classification of rare white blood cells in FPM with a physics-inspired GAN.

Autori: Hassini H Dorizzi B Leymarie V a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42310. Date of Electronic Publication: 2025 Nov 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leukocytes*/classification , Leukocytes*/cytology , Microscopy*/methods , Image Processing, Computer-Assisted*/methods, Humans ; Basophils/cytology ; Basophils/classification ; Algorithms ; Fourier Analysis

Level of DNA damage in peripheral blood mononuclear cells in endometrial cancer patients according to histological type and tumor differentiation.

Autori: Marković A Živković Radojević M Milošević-Djordjević O

Zdroj: Molecular biology reports [Mol Biol Rep] 2025 Nov 26; Vol. 53 (1), pp. 128. Date of Electronic Publication: 2025 Nov 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endometrial Neoplasms*/genetics , Endometrial Neoplasms*/pathology , DNA Damage*/genetics , Leukocytes, Mononuclear*/metabolism , Leukocytes, Mononuclear*/pathology, Humans ; Female ; Middle Aged ; Aged ; Adult ; Comet Assay ; Case-Control Studies ; Neoplasm Grading ; Neoplasm Staging ; Cell Differentiation/genetics ; Body Mass Index

Gut Microbes Secretions May Trigger Mononuclear Cell Migration and Offer Comorbidity Mechanism Between Inflammatory Bowel Disease and Diabetic Retinopathy.

Autori: Xu B Wu S Huang J a ďalší

Zdroj: Mediators of inflammation [Mediators Inflamm] 2025 Nov 24; Vol. 2025, pp. 9894696. Date of Electronic Publication: 2025 Nov 24 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 9209001 Publication Model: eCollection Cited Medium: Internet ISSN: 1466-1861 (Electronic) Linking ISSN: 09629351 NLM ISO Abbreviation: Mediators Inflamm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Inflammatory Bowel Diseases*/metabolism , Inflammatory Bowel Diseases*/microbiology , Gastrointestinal Microbiome*/physiology , Leukocytes, Mononuclear*/metabolism , Leukocytes, Mononuclear*/cytology , Diabetic Retinopathy*/metabolism , Diabetic Retinopathy*/microbiology, Humans ; Cell Movement/physiology ; Male ; Female ; Middle Aged ; Adult

White Blood Cells in Neurodegenerative Diseases in the Context of Neuroinflammation.

Autori: Wełnicka-Wesołowska A Gołąb-Janowska M

Zdroj: Molecular neurobiology [Mol Neurobiol] 2025 Nov 24; Vol. 63 (1), pp. 160. Date of Electronic Publication: 2025 Nov 24.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neurodegenerative Diseases*/blood , Neurodegenerative Diseases*/pathology , Neurodegenerative Diseases*/immunology , Neuroinflammatory Diseases*/pathology , Neuroinflammatory Diseases*/blood , Neuroinflammatory Diseases*/immunology , Leukocytes*/pathology , Leukocytes*/immunology, Humans ; Animals ; Microglia/pathology ; Inflammation/pathology

Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways.

Autori: Girón-Pérez MI Ramírez-Ibarra KM Covantes-Rosales CE a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 20; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cichlids*/metabolism , Cichlids*/genetics , Cichlids*/immunology , Leukocytes*/metabolism , Leukocytes*/drug effects , Fish Proteins*/genetics , Fish Proteins*/metabolism , Transcription Factors*/metabolism , Transcription Factors*/genetics, Animals ; Gene Expression Regulation/drug effects ; Nuclear Receptor Subfamily 1, Group F, Member 3/genetics ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; T-Box Domain Proteins/genetics ; T-Box Domain Proteins/metabolism ; Acetylcholine/metabolism ; T-bet Transcription Factor ; Signal Transduction