Výsledky vyhľadávania - "LIGAND"

TRAIL-resistant glioma cells resist Withania somnifera mediated apoptosis via USP5 upregulation.

Autori: Bhardwaj S Yadav AK

Zdroj: Scientific reports [Sci Rep] 2025 Oct 01; Vol. 15 (1), pp. 34133. Date of Electronic Publication: 2025 Oct 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: TNF-Related Apoptosis-Inducing Ligand*/pharmacology , TNF-Related Apoptosis-Inducing Ligand*/metabolism , Apoptosis*/drug effects , Glioma*/drug therapy , Glioma*/metabolism , Glioma*/pathology , Glioma*/genetics , Withania*/chemistry , Drug Resistance, Neoplasm*/drug effects , Plant Extracts*/pharmacology , Brain Neoplasms*/drug therapy , Brain Neoplasms*/metabolism , Brain Neoplasms*/pathology , Endopeptidases*/metabolism , Endopeptidases*/genetics, Humans ; Cell Line, Tumor ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Up-Regulation/drug effects ; Cell Survival/drug effects ; Gene Expression Regulation, Neoplastic/drug effects

Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors.

Autori: Duranti C Iorio J Capitani C a ďalší

Zdroj: Molecular cancer therapeutics [Mol Cancer Ther] 2025 Oct 01; Vol. 24 (10), pp. 1584-1599.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism , Receptors, TNF-Related Apoptosis-Inducing Ligand*/antagonists & inhibitors , Integrin beta1*/metabolism , Integrin beta1*/immunology , Single-Chain Antibodies*/pharmacology , Ether-A-Go-Go Potassium Channels*/immunology , Ether-A-Go-Go Potassium Channels*/antagonists & inhibitors , Ether-A-Go-Go Potassium Channels*/metabolism , Antineoplastic Agents*/pharmacology, Humans ; Animals ; Mice ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Female ; Apoptosis/drug effects ; ERG1 Potassium Channel ; TNF-Related Apoptosis-Inducing Ligand/genetics ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/pathology

Antitumor Immunity Mediated by Engineered Stem Cells Exploiting TRAIL-Induced Cell Death and FLT3L Immunomodulation.

Autori: van Schaik TA Chen KS Kanaya N a ďalší

Zdroj: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Jul 01; Vol. 31 (13), pp. 2793-2813.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: TNF-Related Apoptosis-Inducing Ligand*/genetics , TNF-Related Apoptosis-Inducing Ligand*/metabolism , Membrane Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/immunology , Glioblastoma*/immunology , Glioblastoma*/therapy , Glioblastoma*/pathology , Glioblastoma*/genetics , Brain Neoplasms*/immunology , Brain Neoplasms*/therapy , Brain Neoplasms*/pathology , Brain Neoplasms*/genetics, Animals ; Humans ; Mice ; Immunomodulation ; Cell Line, Tumor ; Disease Models, Animal ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Mesenchymal Stem Cells/metabolism ; Mesenchymal Stem Cells/immunology ; Tumor Microenvironment/immunology ; Apoptosis/immunology ; Mesenchymal Stem Cell Transplantation ; Cell Death

FEM1B enhances TRAIL-induced apoptosis in T lymphocytes and monocytes.

Autori: Yang C Yu W Dang C a ďalší

Zdroj: FEBS open bio [FEBS Open Bio] 2025 Aug; Vol. 15 (8), pp. 1319-1335. Date of Electronic Publication: 2025 May 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE

Výrazy zo slovníka MeSH: Apoptosis*/drug effects , Monocytes*/metabolism , TNF-Related Apoptosis-Inducing Ligand*/metabolism , TNF-Related Apoptosis-Inducing Ligand*/pharmacology , T-Lymphocytes*/metabolism , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics, Humans ; Animals ; Mice ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Jurkat Cells ; TNF Receptor-Associated Factor 2/metabolism ; Cell Line, Tumor ; Caspase 8/metabolism

R5S4TRAIL ameliorates radiation-induced pulmonary fibrosis by alleviating inflammatory responses and promoting apoptosis of fibroblasts.

Autori: Zhao Y Wei Y Hou W a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Jul 31; Vol. 16, pp. 1600776. Date of Electronic Publication: 2025 Jul 31 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/pathology , Fibroblasts*/radiation effects , Apoptosis*/drug effects , TNF-Related Apoptosis-Inducing Ligand*/pharmacology , TNF-Related Apoptosis-Inducing Ligand*/genetics , Pulmonary Fibrosis*/etiology , Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/pathology , Pulmonary Fibrosis*/metabolism, Animals ; Mice ; Mice, Inbred C57BL ; Humans ; Male ; Disease Models, Animal ; Inflammation/drug therapy ; Lung/pathology ; Lung/drug effects ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism

Design of TNFR peptide agonists for inducing receptor oligomerization and cell apoptosis.

Autori: Liu YX Wang H

Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2025 Jul 22; Vol. 61 (60), pp. 11235-11238. Date of Electronic Publication: 2025 Jul 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Apoptosis*/drug effects , Peptides*/pharmacology , Peptides*/chemistry , Peptides*/chemical synthesis , Drug Design* , Receptors, TNF-Related Apoptosis-Inducing Ligand*/agonists , Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism , fas Receptor*/metabolism , fas Receptor*/agonists , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis, Humans ; Cell Line, Tumor ; TNF-Related Apoptosis-Inducing Ligand/chemistry

Ionizing Radiation Increases Death Receptor 5 (DR5)-Mediated Cell Death, but Not Death Receptor 4 (DR4)-Mediated Cell Death in 3D Tumor Spheroids.

Autori: Suo F Zhou X Soto-Gamez A a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 May 13; Vol. 26 (10). Date of Electronic Publication: 2025 May 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism , Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics , Spheroids, Cellular*/metabolism , Spheroids, Cellular*/radiation effects , Spheroids, Cellular*/drug effects , Radiation, Ionizing* , Apoptosis*/radiation effects , Apoptosis*/drug effects, Humans ; Cell Line, Tumor ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Cell Death/radiation effects

Attenuation of cardiac ischemia/reperfusion injury via the decoy receptor DcR2 by targeting the PLAD domain of the death receptor DR5.

Autori: Zhang L Zhang X Li Z a ďalší

Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2025 May; Vol. 308 (Pt 3), pp. 142529. Date of Electronic Publication: 2025 Mar 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myocardial Reperfusion Injury*/metabolism , Myocardial Reperfusion Injury*/pathology , Myocardial Reperfusion Injury*/genetics , Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism , Receptors, TNF-Related Apoptosis-Inducing Ligand*/chemistry , Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics, Animals ; Mice ; Apoptosis/drug effects ; Male ; Humans ; Protein Domains ; Disease Models, Animal ; Protein Binding ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Mice, Inbred C57BL

MOTS-c relieves hepatocellular carcinoma resistance to TRAIL-induced apoptosis under hypoxic conditions by activating MEF2A.

Autori: Shen H Nie J Wang X a ďalší

Zdroj: Experimental cell research [Exp Cell Res] 2025 Jan 01; Vol. 444 (1), pp. 114354. Date of Electronic Publication: 2024 Nov 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2422 (Electronic) Linking ISSN: 00144827 NLM ISO Abbreviation: Exp Cell Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/genetics , Carcinoma, Hepatocellular*/drug therapy , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Liver Neoplasms*/genetics , Liver Neoplasms*/drug therapy , Apoptosis*/drug effects , TNF-Related Apoptosis-Inducing Ligand*/metabolism , TNF-Related Apoptosis-Inducing Ligand*/pharmacology , MEF2 Transcription Factors*/metabolism , MEF2 Transcription Factors*/genetics , Mice, Nude*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Male ; Female ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Mice, Inbred BALB C ; Xenograft Model Antitumor Assays ; Middle Aged ; Cell Hypoxia/drug effects

DR5 is a restriction factor for human herpesviruses.

Autori: Han C Gui C Su B a ďalší

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Mar 18; Vol. 122 (11), pp. e2417372122. Date of Electronic Publication: 2025 Mar 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy zo slovníka MeSH: Herpesvirus 8, Human*/physiology , Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism , Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics , Herpesviridae*/physiology, Humans ; Apoptosis ; Virus Replication ; Animals ; HEK293 Cells ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Herpesvirus 4, Human

Study of TRAIL and SAHA Co-Treatment on Leukemia K562 Cell Line.

Autori: Alaei A Solali S Mirzapour MM

Zdroj: Cell biochemistry and biophysics [Cell Biochem Biophys] 2025 Mar; Vol. 83 (1), pp. 1087-1096. Date of Electronic Publication: 2024 Oct 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 9701934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0283 (Electronic) Linking ISSN: 10859195 NLM ISO Abbreviation: Cell Biochem Biophys Subsets: MEDLINE

Výrazy zo slovníka MeSH: TNF-Related Apoptosis-Inducing Ligand*/pharmacology , Hydroxamic Acids*/pharmacology , Antineoplastic Agents*/pharmacology, Humans ; K562 Cells ; Vorinostat ; Apoptosis/drug effects ; HEK293 Cells ; Transcription Factor CHOP/metabolism ; Transcription Factor CHOP/genetics ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Signal Transduction/drug effects ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; STAT3 Transcription Factor/metabolism ; Drug Resistance, Neoplasm/drug effects

TRAIL agonists rescue mice from radiation-induced lung, skin, or esophageal injury.

Autori: Strandberg J Louie A Lee S a ďalší

Zdroj: The Journal of clinical investigation [J Clin Invest] 2025 Jan 14; Vol. 135 (5). Date of Electronic Publication: 2025 Jan 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Výrazy zo slovníka MeSH: TNF-Related Apoptosis-Inducing Ligand*/agonists , TNF-Related Apoptosis-Inducing Ligand*/pharmacology , Radiation Injuries, Experimental*/pathology , Radiation Injuries, Experimental*/drug therapy , Radiation Injuries, Experimental*/metabolism , Radiation Injuries, Experimental*/genetics , Esophagus*/pathology , Esophagus*/radiation effects , Radiation Pneumonitis*/pathology , Radiation Pneumonitis*/drug therapy , Radiation Pneumonitis*/metabolism , Radiation Pneumonitis*/prevention & control , Skin*/radiation effects , Skin*/pathology, Animals ; Mice ; Female ; Male ; Humans ; Receptors, TNF-Related Apoptosis-Inducing Ligand/agonists ; Lung/pathology ; Lung/radiation effects

The generation of stable microvessels in ischemia is mediated by endothelial cell derived TRAIL.

Autori: Cartland SP Patil MS Kelland E a ďalší

Zdroj: Science advances [Sci Adv] 2024 Oct 04; Vol. 10 (40), pp. eadn8760. Date of Electronic Publication: 2024 Oct 04.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endothelial Cells*/metabolism , Ischemia*/metabolism , Ischemia*/pathology , Microvessels*/metabolism , Microvessels*/pathology , TNF-Related Apoptosis-Inducing Ligand*/metabolism , TNF-Related Apoptosis-Inducing Ligand*/genetics, Animals ; Humans ; Male ; Mice ; Disease Models, Animal ; Heparin-binding EGF-like Growth Factor/metabolism ; Heparin-binding EGF-like Growth Factor/genetics ; Neovascularization, Physiologic ; Pericytes/metabolism ; Pericytes/pathology ; Peripheral Arterial Disease/metabolism ; Peripheral Arterial Disease/pathology ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Adult ; Female

Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer.

Autori: Li J Arnold J Sima M a ďalší

Zdroj: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Dec; Vol. 376, pp. 1014-1024. Date of Electronic Publication: 2024 Nov 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptors, TNF-Related Apoptosis-Inducing Ligand*/agonists , Colonic Neoplasms*/drug therapy , Colonic Neoplasms*/pathology , Histone Deacetylase Inhibitors*/pharmacology , Histone Deacetylase Inhibitors*/administration & dosage , Histone Deacetylase Inhibitors*/chemistry , Histone Deacetylase Inhibitors*/therapeutic use , Apoptosis*/drug effects, Humans ; Cell Line, Tumor ; TNF-Related Apoptosis-Inducing Ligand/administration & dosage ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; Acrylamides/chemistry ; Acrylamides/pharmacology ; Mice, Nude

Trans cinnamaldehyde enhances TRAIL induced apoptosis through ER stress mediated upregulation of DR5 in colorectal cancer cells.

Autori: Kim DY Kim BG Yun HM a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 06; Vol. 15 (1), pp. 38840. Date of Electronic Publication: 2025 Nov 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: TNF-Related Apoptosis-Inducing Ligand*/pharmacology , Endoplasmic Reticulum Stress*/drug effects , Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism , Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics , Acrolein*/analogs & derivatives , Acrolein*/pharmacology , Apoptosis*/drug effects , Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/genetics, Humans ; Cell Line, Tumor ; Transcription Factor CHOP/metabolism ; Transcription Factor CHOP/genetics ; Animals ; Up-Regulation/drug effects ; Mice ; Drug Synergism ; Xenograft Model Antitumor Assays ; Gene Expression Regulation, Neoplastic/drug effects ; Mice, Nude

Endometriotic Tissue-derived Exosomes Downregulate NKG2D-mediated Cytotoxicity and Promote Apoptosis: Mechanisms for Survival of Ectopic Endometrial Tissue in Endometriosis.

Autori: Björk E Israelsson P Nagaev I a ďalší

Zdroj: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 Sep 01; Vol. 213 (5), pp. 567-576.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endometriosis*/immunology , Endometriosis*/metabolism , Endometriosis*/pathology , Exosomes*/metabolism , Exosomes*/immunology , NK Cell Lectin-Like Receptor Subfamily K*/metabolism , Apoptosis*/immunology , Endometrium*/immunology , Endometrium*/pathology , Endometrium*/metabolism , TNF-Related Apoptosis-Inducing Ligand*/metabolism , TNF-Related Apoptosis-Inducing Ligand*/immunology, Humans ; Female ; Down-Regulation/immunology ; Fas Ligand Protein/metabolism ; Fas Ligand Protein/immunology ; Cytotoxicity, Immunologic ; Adult ; Histocompatibility Antigens Class I/metabolism ; Histocompatibility Antigens Class I/immunology

Dual-sensitization nanoformulation combining glutamine metabolism inhibition and Fas/FasL activation for enhanced colorectal cancer immunotherapy.

Autori: Yan D Yi W Wu T a ďalší

Zdroj: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2025 Dec 10; Vol. 388 (Pt 1), pp. 114324. Date of Electronic Publication: 2025 Oct 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

Výrazy zo slovníka MeSH: Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/immunology , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/metabolism , Glutamine*/metabolism , Fas Ligand Protein*/metabolism , Fas Ligand Protein*/immunology , fas Receptor*/metabolism , fas Receptor*/immunology , Immune Checkpoint Inhibitors*/administration & dosage, Humans ; Animals ; Immunotherapy/methods ; B7-H1 Antigen/immunology ; Cell Line, Tumor ; Mice ; Dendritic Cells/immunology ; Female ; Amino Acid Transport System ASC/antagonists & inhibitors ; Mice, Inbred C57BL ; Apoptosis/drug effects

The RANK-RANKL-OPG axis in dermatological malignancies: A systematic review.

Autori: Zartab H Maghsoodloo D Parsi-Moud A a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115624. Date of Electronic Publication: 2025 Oct 15.

Spôsob vydávania: Journal Article; Systematic Review

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoprotegerin*/metabolism , RANK Ligand*/metabolism , Receptor Activator of Nuclear Factor-kappa B*/metabolism , Skin Neoplasms*/drug therapy , Skin Neoplasms*/immunology , Skin Neoplasms*/metabolism , Skin Neoplasms*/pathology, Animals ; Humans ; Denosumab/therapeutic use ; Signal Transduction

Biological targeted therapy for lupus nephritis-the role of BLYS and APRIL.

Autori: Yang X Liu S Liu XJ a ďalší

Zdroj: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2561791. Date of Electronic Publication: 2025 Nov 17.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lupus Nephritis*/drug therapy , Lupus Nephritis*/immunology , B-Cell Activating Factor*/antagonists & inhibitors , B-Cell Activating Factor*/metabolism , B-Cell Activating Factor*/immunology , Tumor Necrosis Factor Ligand Superfamily Member 13*/antagonists & inhibitors , Tumor Necrosis Factor Ligand Superfamily Member 13*/metabolism , Tumor Necrosis Factor Ligand Superfamily Member 13*/immunology, Humans ; Antibodies, Monoclonal, Humanized/therapeutic use ; Rituximab/therapeutic use ; Immunosuppressive Agents/therapeutic use ; Recombinant Fusion Proteins/therapeutic use ; B-Lymphocytes/immunology ; Molecular Targeted Therapy

Treatment of pemphigus and other neglected skin conditions with PC111, a human anti-Fas Ligand monoclonal antibody: a potential disease modifier.

Autori: Lotti R Amato A Bennett B a ďalší

Zdroj: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2526075. Date of Electronic Publication: 2025 Jul 02.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pemphigus*/drug therapy , Pemphigus*/immunology , Stevens-Johnson Syndrome*/drug therapy , Stevens-Johnson Syndrome*/immunology , Fas Ligand Protein*/immunology , Fas Ligand Protein*/antagonists & inhibitors , Antibodies, Monoclonal*/therapeutic use , Antibodies, Monoclonal*/pharmacology , Antibodies, Monoclonal, Humanized*/therapeutic use, Humans ; Animals ; Keratinocytes/drug effects ; Apoptosis/drug effects ; Autoantibodies/immunology