Výsledky vyhľadávania - "LEFLUNOMIDE"

Proteins linked to type II interferon response in Sjögren's disease: novel indicators for disease monitoring and predicting treatment response to leflunomide and hydroxychloroquine combination therapy.

Autori: Wong WY Leavis HL Blokland SLM a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 17; Vol. 16, pp. 1566377. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Randomized Controlled Trial

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Hydroxychloroquine*/therapeutic use , Hydroxychloroquine*/administration & dosage , Leflunomide*/therapeutic use , Leflunomide*/administration & dosage , Sjogren's Syndrome*/drug therapy , Sjogren's Syndrome*/immunology , Sjogren's Syndrome*/blood , Sjogren's Syndrome*/diagnosis , Sjogren's Syndrome*/metabolism , Interferon-gamma*, Humans ; Female ; Middle Aged ; Male ; Drug Therapy, Combination ; Biomarkers/blood ; Adult ; Treatment Outcome ; Proteomics/methods ; Aged ; Antirheumatic Agents/therapeutic use ; Proteome

Dopamine agonist pramipexole halts leflunomide nephrotoxicity: A dual strike on TLR4-Driven inflammation and PI3K/Akt suppression.

Autori: Mustafa AM Aljarba NH Zouganelis GD a ďalší

Zdroj: European journal of pharmacology [Eur J Pharmacol] 2025 Nov 15; Vol. 1007, pp. 178267. Date of Electronic Publication: 2025 Oct 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proto-Oncogene Proteins c-akt*/metabolism , Toll-Like Receptor 4*/metabolism , Leflunomide*/adverse effects , Phosphatidylinositol 3-Kinases*/metabolism , Pramipexole*/pharmacology , Dopamine Agonists*/pharmacology , Dopamine Agonists*/therapeutic use , Kidney*/drug effects , Kidney*/pathology , Kidney*/metabolism, Animals ; Mice ; Male ; Inflammation/drug therapy ; Inflammation/metabolism ; Oxidative Stress/drug effects ; Signal Transduction/drug effects ; Apoptosis/drug effects ; Mice, Inbred C57BL

Development, characterization, and optimization of folate-chitosan surface-modified PLGA-decorated mesoporous silica nanoparticles for effective delivery of leflunomide for the management of rheumatoid arthritis.

Autori: El-Dakroury WA El-Tokhy FS Asaad GF a ďalší

Zdroj: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2025 Sep; Vol. 214, pp. 114808. Date of Electronic Publication: 2025 Jul 09.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9109778 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3441 (Electronic) Linking ISSN: 09396411 NLM ISO Abbreviation: Eur J Pharm Biopharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/administration & dosage , Leflunomide*/pharmacokinetics , Chitosan*/chemistry , Arthritis, Rheumatoid*/drug therapy , Nanoparticles*/chemistry , Silicon Dioxide*/chemistry , Polylactic Acid-Polyglycolic Acid Copolymer*/chemistry , Folic Acid*/chemistry , Antirheumatic Agents*/administration & dosage, Animals ; Rats ; Drug Liberation ; Male ; Drug Carriers/chemistry ; Particle Size ; Drug Delivery Systems/methods ; Arthritis, Experimental/drug therapy ; Porosity ; Rats, Sprague-Dawley ; Biological Availability ; Surface Properties ; Administration, Oral

Leflunomide-Mediated Immunomodulation Inhibits Lesion Progression in a Vitiligo Mouse Model.

Autori: Miao F Li X Zhao L a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 15; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Vitiligo*/drug therapy , Vitiligo*/immunology , Vitiligo*/pathology , Vitiligo*/metabolism , Leflunomide*/pharmacology , Leflunomide*/therapeutic use , Immunomodulation*/drug effects, Animals ; Mice ; Disease Models, Animal ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/drug effects ; Cytokines/metabolism ; Disease Progression ; Chemokine CXCL9/metabolism ; Interferon-gamma/metabolism

Design and development of leflunomide loaded topical microsponge gel: insights from ex vivo and in vivo inflammatory studies.

Autori: Shah N Patel P Gohil D a ďalší

Zdroj: Pharmaceutical development and technology [Pharm Dev Technol] 2025 Jul; Vol. 30 (6), pp. 863-874. Date of Electronic Publication: 2025 Jun 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9610932 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9867 (Electronic) Linking ISSN: 10837450 NLM ISO Abbreviation: Pharm Dev Technol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/administration & dosage , Leflunomide*/chemistry , Leflunomide*/pharmacology , Leflunomide*/pharmacokinetics , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage, Animals ; Rats ; Rats, Wistar ; Particle Size ; Gels/chemistry ; Drug Liberation ; Skin Absorption/drug effects ; Male ; Drug Carriers/chemistry ; Cellulose/chemistry ; Cellulose/analogs & derivatives ; Skin/drug effects ; Skin/metabolism ; Administration, Cutaneous ; Delayed-Action Preparations

OpenSAFELY: The impact of COVID-19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate.

Autori: Brown AD Fisher L Curtis HJ a ďalší

Korporácia: Brown AD Fisher L Curtis HJ a ďalší

Zdroj: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Jun; Vol. 91 (6), pp. 1586-1599. Date of Electronic Publication: 2024 Apr 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/adverse effects , Leflunomide*/therapeutic use , Leflunomide*/administration & dosage , COVID-19*/epidemiology , Antirheumatic Agents*/adverse effects , Antirheumatic Agents*/therapeutic use , Antirheumatic Agents*/administration & dosage , Drug Monitoring*/statistics & numerical data , Drug Monitoring*/methods , Azathioprine*/adverse effects , Azathioprine*/therapeutic use , Azathioprine*/administration & dosage , Methotrexate*/adverse effects , Methotrexate*/therapeutic use , Methotrexate*/administration & dosage, Humans ; Female ; Male ; Aged ; Middle Aged ; Adult ; Cohort Studies ; COVID-19 Drug Treatment ; Electronic Health Records ; SARS-CoV-2 ; Young Adult

Transcriptomic analysis of the anti-tumor effects of leflunomide in prolactinoma.

Autori: Pei X Peng Y Yin H a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Apr 05; Vol. 15 (1), pp. 11703. Date of Electronic Publication: 2025 Apr 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/pharmacology , Prolactinoma*/drug therapy , Prolactinoma*/genetics , Prolactinoma*/pathology , Prolactinoma*/metabolism , Pituitary Neoplasms*/drug therapy , Pituitary Neoplasms*/genetics , Pituitary Neoplasms*/pathology , Pituitary Neoplasms*/metabolism , Transcriptome* , Antineoplastic Agents*/pharmacology, Animals ; Rats ; Cell Line, Tumor ; Gene Expression Profiling ; Cell Proliferation/drug effects ; Cabergoline/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Apoptosis/drug effects ; Protein Interaction Maps/drug effects ; Male

Evaluating leflunomide and methotrexate combination vs. monotherapy in rheumatoid and psoriatic arthritis.

Autori: Kara M Alp G Pekdiker M a ďalší

Zdroj: Turkish journal of medical sciences [Turk J Med Sci] 2025 Mar 24; Vol. 55 (3), pp. 632-643. Date of Electronic Publication: 2025 Mar 24 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: Scientific and Technical Research Council of Turkey Country of Publication: Turkey NLM ID: 9441758 Publication Model: eCollection Cited Medium: Internet ISSN: 1303-6165 (Electronic) Linking ISSN: 13000144 NLM ISO Abbreviation: Turk J Med Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/therapeutic use , Leflunomide*/adverse effects , Leflunomide*/administration & dosage , Methotrexate*/therapeutic use , Methotrexate*/adverse effects , Methotrexate*/administration & dosage , Arthritis, Psoriatic*/drug therapy , Arthritis, Rheumatoid*/drug therapy , Antirheumatic Agents*/therapeutic use , Antirheumatic Agents*/adverse effects , Antirheumatic Agents*/administration & dosage, Humans ; Male ; Female ; Middle Aged ; Drug Therapy, Combination ; Adult ; Aged ; Treatment Outcome ; Isoxazoles ; Retrospective Studies

Study on the Mechanism of the Combination of Methotrexate and Leflunomide in the Treatment of Rheumatoid Arthritis Based on Network Pharmacology, Molecular Docking, and in vitro Experimental Verification.

Autori: Shi J Cui X Wang Y a ďalší

Zdroj: Combinatorial chemistry & high throughput screening [Comb Chem High Throughput Screen] 2025; Vol. 28 (11), pp. 1815-1831.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9810948 Publication Model: Print Cited Medium: Internet ISSN: 1875-5402 (Electronic) Linking ISSN: 13862073 NLM ISO Abbreviation: Comb Chem High Throughput Screen Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/pharmacology , Leflunomide*/chemistry , Molecular Docking Simulation* , Methotrexate*/pharmacology , Methotrexate*/chemistry , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/metabolism , Network Pharmacology* , Antirheumatic Agents*/pharmacology , Antirheumatic Agents*/chemistry, Humans ; Animals ; Drug Therapy, Combination

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome with Multiple Drugs (Leflunomide and Cefuroxime): A Case Report.

Autori: Yadav P Rao GK Rataboli PV a ďalší

Zdroj: Current drug safety [Curr Drug Saf] 2025; Vol. 20 (3), pp. 388-393.

Spôsob vydávania: Case Reports; Journal Article

Informácie o časopise: Publisher: Saif Zone, Sharjah, U.A.E. Country of Publication: United Arab Emirates NLM ID: 101270895 Publication Model: Print Cited Medium: Internet ISSN: 2212-3911 (Electronic) Linking ISSN: 15748863 NLM ISO Abbreviation: Curr Drug Saf Subsets: MEDLINE

Výrazy zo slovníka MeSH: Drug Hypersensitivity Syndrome*/etiology , Drug Hypersensitivity Syndrome*/diagnosis , Leflunomide*/adverse effects , Leflunomide*/administration & dosage , Cefuroxime*/adverse effects , Cefuroxime*/administration & dosage , Anti-Bacterial Agents*/adverse effects , Anti-Bacterial Agents*/administration & dosage, Humans ; Female ; Adult ; Eosinophilia/chemically induced

Microbiota-indole-3-propionic acid-heart axis mediates the protection of leflunomide against αPD1-induced cardiotoxicity in mice.

Autori: Huang R Shen ZY Huang D a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Mar 19; Vol. 16 (1), pp. 2651. Date of Electronic Publication: 2025 Mar 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/pharmacology , Leflunomide*/therapeutic use , Cardiotoxicity*/prevention & control , Cardiotoxicity*/etiology , Cardiotoxicity*/metabolism , Gastrointestinal Microbiome*/drug effects , Indoles*/pharmacology , Indoles*/metabolism , Programmed Cell Death 1 Receptor*/antagonists & inhibitors , Heart*/drug effects , Propionates*/metabolism , Propionates*/pharmacology, Animals ; Mice ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Mice, Inbred C57BL ; Male ; Receptors, Aryl Hydrocarbon/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Fecal Microbiota Transplantation ; Immune Checkpoint Inhibitors/adverse effects

Leflunomide exerts neuroprotective effects in an MPTP‑treated mouse model of Parkinsonism.

Autori: Civil Ürkmez Y Kirmizikan S Günaydin C a ďalší

Zdroj: Acta neurobiologiae experimentalis [Acta Neurobiol Exp (Wars)] 2025 Jan 14; Vol. 84 (4), pp. 319-331. Date of Electronic Publication: 2025 Jan 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nencki Institute of Experimental Biology Country of Publication: Poland NLM ID: 1246675 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-0035 (Electronic) Linking ISSN: 00651400 NLM ISO Abbreviation: Acta Neurobiol Exp (Wars) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/pharmacology , Leflunomide*/therapeutic use , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/therapeutic use , Parkinsonian Disorders*/drug therapy , MPTP Poisoning*/drug therapy, Animals ; Mice ; Male ; Disease Models, Animal ; Motor Activity/drug effects ; Mice, Inbred C57BL ; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/pharmacology

Leflunomide-induced drug reaction eosinophilia systemic symptoms and haemophagocytic lymphohistiocytosis overlap syndrome with rheumatoid arthritis.

Autori: Sebastian AP Tirlangi PK Saravu K a ďalší

Zdroj: BMJ case reports [BMJ Case Rep] 2025 Jan 29; Vol. 18 (1). Date of Electronic Publication: 2025 Jan 29.

Spôsob vydávania: Journal Article; Case Reports

Informácie o časopise: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antirheumatic Agents*/adverse effects , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/complications , Drug Hypersensitivity Syndrome*/etiology , Drug Hypersensitivity Syndrome*/diagnosis , Drug Hypersensitivity Syndrome*/drug therapy , Drug Hypersensitivity Syndrome*/complications , Leflunomide*/adverse effects , Lymphohistiocytosis, Hemophagocytic*/chemically induced , Lymphohistiocytosis, Hemophagocytic*/complications , Lymphohistiocytosis, Hemophagocytic*/drug therapy , Lymphohistiocytosis, Hemophagocytic*/diagnosis, Female ; Humans ; Middle Aged ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/therapeutic use ; Isoxazoles/adverse effects ; Piperidines/therapeutic use ; Pyrimidines/therapeutic use

Leflunomide-Associated Wound Complication After Cochlear Implantation: A Case Report.

Autori: Munjal V Macielak RJ Kaul VF a ďalší

Zdroj: The Annals of otology, rhinology, and laryngology [Ann Otol Rhinol Laryngol] 2024 Oct; Vol. 133 (10), pp. 898-901. Date of Electronic Publication: 2024 Jul 25.

Spôsob vydávania: Journal Article; Case Reports

Informácie o časopise: Publisher: Sage Country of Publication: United States NLM ID: 0407300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-572X (Electronic) Linking ISSN: 00034894 NLM ISO Abbreviation: Ann Otol Rhinol Laryngol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/adverse effects , Leflunomide*/therapeutic use , Cochlear Implantation*/adverse effects , Surgical Wound Dehiscence*/chemically induced , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/surgery , Immunosuppressive Agents*/adverse effects, Humans ; Male ; Aged, 80 and over ; Surgical Wound Infection ; Antirheumatic Agents/adverse effects

Gold-thiol-beaded albumin nanoparticles for chemo-combined pulsatile plasmonic laser therapy of Rheumatoid arthritis in rat model.

Autori: Gadeval A Anup N Pawar B a ďalší

Zdroj: International journal of pharmaceutics [Int J Pharm] 2024 Dec 25; Vol. 667 (Pt A), pp. 124882. Date of Electronic Publication: 2024 Oct 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Arthritis, Rheumatoid*/drug therapy , Gold*/chemistry , Gold*/administration & dosage , Leflunomide*/administration & dosage , Arthritis, Experimental*/drug therapy , Sulfhydryl Compounds*/chemistry , Sulfhydryl Compounds*/administration & dosage, Animals ; RAW 264.7 Cells ; Mice ; Rats ; Male ; Albumins/administration & dosage ; Albumins/chemistry ; Antirheumatic Agents/administration & dosage ; Antirheumatic Agents/pharmacokinetics ; Antirheumatic Agents/chemistry ; Antirheumatic Agents/pharmacology ; Nanoparticles ; Drug Liberation ; Laser Therapy/methods ; Rats, Sprague-Dawley ; Disease Models, Animal

Resolution of Plaque Keratopathy in a Patient with Atopic Keratoconjunctivitis After Treatment with Leflunomide.

Autori: Park RB Djalilian AR

Zdroj: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Dec; Vol. 32 (10), pp. 2572-2574. Date of Electronic Publication: 2024 Jul 25.

Spôsob vydávania: Case Reports; Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5078 (Electronic) Linking ISSN: 09273948 NLM ISO Abbreviation: Ocul Immunol Inflamm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/therapeutic use , Conjunctivitis, Allergic*/drug therapy , Conjunctivitis, Allergic*/diagnosis, Humans ; Male ; Middle Aged ; Immunosuppressive Agents/therapeutic use ; Visual Acuity

Leflunomide nanocarriers: a new prospect of therapeutic applications.

Autori: Zewail M; Department of Pharmaceutics, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt.

Zdroj: Journal of microencapsulation [J Microencapsul] 2024 Dec; Vol. 41 (8), pp. 715-738. Date of Electronic Publication: 2024 Sep 25.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8500513 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-5246 (Electronic) Linking ISSN: 02652048 NLM ISO Abbreviation: J Microencapsul Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leflunomide*/chemistry , Leflunomide*/therapeutic use , Leflunomide*/pharmacology , Leflunomide*/pharmacokinetics , Hydroxybutyrates*/chemistry , Antirheumatic Agents*/administration & dosage , Antirheumatic Agents*/pharmacokinetics , Antirheumatic Agents*/chemistry , Antirheumatic Agents*/therapeutic use , Antirheumatic Agents*/pharmacology , Toluidines*/chemistry , Toluidines*/therapeutic use , Toluidines*/pharmacokinetics, Humans ; Animals ; Nanoparticles/chemistry ; Nitriles/chemistry ; Drug Carriers/chemistry ; Crotonates/chemistry ; Crotonates/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Neoplasms/drug therapy ; Multiple Sclerosis/drug therapy ; Isoxazoles/chemistry ; Isoxazoles/pharmacokinetics ; Isoxazoles/pharmacology ; Isoxazoles/therapeutic use

Metabolism-based scoring of cutaneous squamous cell carcinoma to predict tumour features and responses to treatment with dihydroorotate dehydrogenase inhibitors.

Autori: Dousset L Khalife F Chalopin-Fillot D a ďalší

Zdroj: The British journal of dermatology [Br J Dermatol] 2025 Oct 17; Vol. 193 (5), pp. 936-947.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Skin Neoplasms*/drug therapy , Skin Neoplasms*/metabolism , Skin Neoplasms*/pathology , Oxidoreductases Acting on CH-CH Group Donors*/antagonists & inhibitors , Oxidoreductases Acting on CH-CH Group Donors*/metabolism , Carcinoma, Squamous Cell*/drug therapy , Carcinoma, Squamous Cell*/metabolism , Carcinoma, Squamous Cell*/pathology , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/therapeutic use, Dihydroorotate Dehydrogenase ; Humans ; Animals ; Leflunomide/pharmacology ; Xenograft Model Antitumor Assays ; Proteomics ; Female ; Mice ; Male

A Longitudinal Study Reveals Metabolomic Markers for Individuals at Risk, Disease Severity, and Treatment Response in Rheumatoid Arthritis.

Autori: Zhu C Xu J He S a ďalší

Zdroj: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Oct; Vol. 12 (38), pp. e04414. Date of Electronic Publication: 2025 Aug 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/metabolism , Arthritis, Rheumatoid*/blood , Arthritis, Rheumatoid*/diagnosis , Biomarkers*/blood , Biomarkers*/metabolism , Metabolomics*/methods, Humans ; Male ; Female ; Longitudinal Studies ; Middle Aged ; Antirheumatic Agents/therapeutic use ; Adult ; Methotrexate/therapeutic use ; Severity of Illness Index ; Aged ; Treatment Outcome ; Hydroxychloroquine/therapeutic use ; Leflunomide/therapeutic use

Prevalence and Risk Factors of COVID-19 Reinfection in Patients with Rheumatoid Arthritis: A Retrospective Observational Study.

Autori: Kim YE Ahn SM Oh JS a ďalší

Zdroj: Yonsei medical journal [Yonsei Med J] 2024 Nov; Vol. 65 (11), pp. 645-650.

Spôsob vydávania: Journal Article; Observational Study

Informácie o časopise: Publisher: Yonsei University Country of Publication: Korea (South) NLM ID: 0414003 Publication Model: Print Cited Medium: Internet ISSN: 1976-2437 (Electronic) Linking ISSN: 05135796 NLM ISO Abbreviation: Yonsei Med J Subsets: MEDLINE

Výrazy zo slovníka MeSH: COVID-19*/epidemiology , COVID-19*/complications , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/complications , Arthritis, Rheumatoid*/epidemiology , Reinfection*/epidemiology , SARS-CoV-2* , Leflunomide*/therapeutic use, Humans ; Female ; Middle Aged ; Male ; Retrospective Studies ; Risk Factors ; Aged ; Prevalence ; Antirheumatic Agents/therapeutic use ; Antirheumatic Agents/adverse effects ; Proportional Hazards Models ; Republic of Korea/epidemiology ; Methotrexate/therapeutic use

SCR Disease Name: COVID-19 reinfection