Suchergebnisse - "KNOCKOUT mice"

Behavioral and molecular effects of environmental and genetic chronodisruption in mice

Autoren: Berbegal Sáez, Paula

Thesis Advisors: Sanz, Ferran, Valverde Granados, Olga

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: Cronodisrupció, Chronodisruption, Rellotge biològic, Biological clock, Ratolí Bmal1 knockout, Bmal1 knockout mice, Comportament, Behavior, Open arrays

Time: 616.8

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/694798

Frem2 knockout mice exhibit Fraser syndrome phenotypes and neonatal lethality due to bilateral renal agenesis.

Autoren: Simikyan, Rubina G. Zhang, Xinyuan Strelkova, Olga et al.

Quelle: Scientific Reports. 9/26/2025, Vol. 15 Issue 1, p1-12. 12p.

Schlagwörter: *NEONATAL death, *KNOCKOUT mice, *LABORATORY mice, *CONGENITAL disorders, *EXTRACELLULAR matrix proteins, *HUMAN abnormalities

Impact of Elovl5 Deficiency on Cerebellar Excitatory Synaptic Transmission in Mice.

Autoren: Montarolo, Francesca Gao, Fangyuan Loddo, Matilde et al.

Quelle: Journal of Neuroscience. 9/17/2025, Vol. 45 Issue 38, p1-15. 15p.

Schlagwörter: *KNOCKOUT mice, *MONOUNSATURATED fatty acids, *SYNAPTIC vesicles, *UNSATURATED fatty acids, *CEREBELLAR cortex, *NEURAL transmission

Supercomplex Restructuring in Heart Mitochondria of COX7A1-Deficient Mice.

Autoren: Pavelich, Lauren Pham, Lucynda Stemmer, Paul et al.

Quelle: Biomolecules (2218-273X). Sep2025, Vol. 15 Issue 9, p1209. 13p.

Schlagwörter: *CYTOCHROME oxidase, *KNOCKOUT mice, *OXIDATIVE phosphorylation, *HYPOTHESIS, *ELECTRON transport

Rescue of Iqsec2 Knockout Mice with Human IQSEC2 Adeno-Associated Virus Mediated Gene Therapy.

Autoren: Soundararajan, Divyalakshmi Kouyama-Suzuki, Emi Shirai, Yoshinori et al.

Quelle: International Journal of Molecular Sciences. Sep2025, Vol. 26 Issue 17, p8311. 18p.

Schlagwörter: *GENE therapy, *KNOCKOUT mice, *STOP codons, *AUTISM, *GUANINE nucleotide exchange factors, *INTELLECTUAL disabilities, *EPILEPSY, *GENETIC vectors

G proteins of the G12 family expressed by POMC neurons regulate key metabolic functions.

Autoren: Haspula, Dhanush Zhenzhong Cui Pittala, Srinivas et al.

Quelle: Science Advances. 7/11/2025, Vol. 11 Issue 28, p1-21. 21p.

Schlagwörter: *G proteins, *KNOCKOUT mice, *NEURONS, *PROOPIOMELANOCORTIN, *LEPTIN, *G protein coupled receptors, *SEROTONIN receptors

Combination of genetic studies and animal modeling proposes TMPRSS9 as a candidate gene for serum K⁺ variations.

Autoren: Auberson, Muriel Wang, Dongmei Ehret, Elodie et al.

Quelle: Scientific Reports. 7/12/2025, Vol. 15 Issue 1, p1-15. 15p.

Schlagwörter: *KNOCKOUT mice, *POTASSIUM metabolism, *GENOME-wide association studies, *ANIMAL models in research, *HYPOKALEMIA, *GENES

Bmal1 Modulates Striatal cAMP Signaling and Motor Learning.

Autoren: Cryan, Casey E. Yini Liao Widjaja, Josephine H. et al.

Quelle: Journal of Neuroscience. 7/9/2025, Vol. 45 Issue 28, p1-16. 16p.

Schlagwörter: *TRANSCRIPTION factors, *KNOCKOUT mice, *ADENYLATE cyclase, *CIRCADIAN rhythms, *CELLULAR signal transduction, *MOTOR learning

Hyperalgesia in the Psychological Stress-Induced Fibromyalgia Model Shows Sexual Dimorphism Mediated by LPA 1 and LPA 3.

Autoren: Ueda, Hiroshi Neyama, Hiroyuki Dozono, Naoki et al.

Quelle: Cells (2073-4409). Jul2025, Vol. 14 Issue 13, p1022. 16p.

Schlagwörter: *KNOCKOUT mice, *SEXUAL dimorphism, *PSYCHOLOGICAL stress, *NEURALGIA, *HYPERALGESIA

Cardiac PAD2 expression and myocardial citrullination decline with age in female mice independent of estrogen.

Autoren: Shorthill, Samantha K. Klinger, Finley R. Yusifov, Aykhan et al.

Quelle: American Journal of Physiology: Heart & Circulatory Physiology. Jul2025, Vol. 329 Issue 1, pH271-H281. 11p.

Schlagwörter: *POST-translational modification, *KNOCKOUT mice, *MASS spectrometry, *OVARIECTOMY, *AGING

Steap3 is a key node in regulating the phagosome escape of Listeria monocytogenes.

Autoren: Li, Zhangfu Shao, Yan Liu, Xiao et al.

Quelle: Molecular Immunology. Jun2025, Vol. 182, p96-106. 11p.

Schlagwörter: *LISTERIOSIS, *KNOCKOUT mice, *DRUG resistance in bacteria, *EPITHELIAL cells, *FOOD pathogens, *LISTERIA monocytogenes

Apolipoprotein-L1 G1 variant contributes to hydrocephalus but not to atherosclerosis in apolipoprotein-E knock-out mice.

Autoren: Teruhiko Yoshida Zhi-Hong Yang Ashida, Shinji et al.

Quelle: Clinical Science. Jun2025, Vol. 139 Issue 11, p559-575. 17p.

Schlagwörter: *BACTERIAL artificial chromosomes, *KNOCKOUT mice, *TRANSGENIC mice, *DISEASE risk factors, *CHOROID plexus

Electroretinographic and Morphological Characterization of the Retina of Annexin A1 Knockout Mice.

Autoren: da Silva, Rafael André Liber, André Maurício Passos de Souza Ferreira, Luiz Philipe et al.

Quelle: Neuroglia. Jun2025, Vol. 6 Issue 2, p19. 14p.

Schlagwörter: *ELECTRORETINOGRAPHY, *KNOCKOUT mice, *MORPHOLOGY, *EYE diseases, *HISTOMORPHOMETRY, *RETINA physiology, *ANNEXINS

心肌和骨骼肌特异性 Cyr61 基因敲除小鼠模型的构建.

Alternate Title: Construction of a myocardial and skeletal muscle-specific Cyr61 gene knockout mouse model.

Autoren: 徐笛艳 张雯莉 左一丹 et al.

Quelle: Basic & Clinical Medicine. Jun2025, Vol. 45 Issue 6, p720-726. 7p.

Schlagwörter: *SKELETAL muscle, *KNOCKOUT mice, *GENE knockout, *MUSCLE strength, *LABORATORY mice

Sex differences in the modulation of anxiety- and depression-like behaviors by matrix metalloproteinase-9 expression levels in mice.

Autoren: Senserrich, Júlia Castro, Elena Florensa-Zanuy, Eva et al.

Quelle: Biology of Sex Differences. 5/22/2025, Vol. 16 Issue 1, p1-16. 16p.

Schlagwörter: *KNOCKOUT mice, *MENTAL depression, *TRANSGENIC mice, *MATRIX metalloproteinases, *NEUROPLASTICITY, *DEPRESSED persons

Complementary corticostriatal circuits orchestrate action repetition and switching.

Autoren: Baibing Zhang Geddes, Claire E. Xin Jin

Quelle: Science Advances. 5/23/2025, Vol. 11 Issue 21, p1-20. 20p.

Schlagwörter: *KNOCKOUT mice, *LABORATORY mice, *INNERVATION, *ANIMAL disease models, *MICE

Hypothalamic Median Eminence Thyrotropin-Releasing Hormone-Degrading Ectoenzyme Activity Is Dispensable for Basal Thyroid Axis Activity in Lean Rodents.

Autoren: Rodríguez-Rodríguez, Adair Uribe, Rosa María Cote-Vélez, Antonieta et al.

Quelle: Cells (2073-4409). May2025, Vol. 14 Issue 10, p725. 27p.

Schlagwörter: *THYROTROPIN releasing factor, *KNOCKOUT mice, *ADENO-associated virus, *MICROINJECTIONS, *THYROID hormones, *HYPOTHALAMUS

A Critical Role of Neuroligin 2 C-Terminus in OCD and Social Behavior.

Autoren: Pandey, Saurabh Ostergren, Sophia Jun Li et al.

Quelle: Journal of Neuroscience. 5/7/2025, Vol. 45 Issue 19, p1-16. 16p.

Schlagwörter: *KNOCKOUT mice, *CELL adhesion molecules, *NEUROBEHAVIORAL disorders, *SOCIAL perception, *OBSESSIVE-compulsive disorder

Deletion of GFRAL blunts weight lowering effects of FGF21 in female mice.

Autoren: Buch-Rasmussen, Alberte Silke Andersen, Helle Stage, Christina et al.

Quelle: Journal of Endocrinology. May2025, Vol. 265 Issue 2, p1-10. 10p.

Schlagwörter: *FIBROBLAST growth factors, *KNOCKOUT mice, *GENE expression, *FOOD consumption, *BODY weight

Cyclophilin D (CypD) ablation prevents neurodegeneration and cognitive damage induced by caspase-3 cleaved tau.

Autoren: Olesen, Margrethe A. Villavicencio-Tejo, Francisca Johnson, Gail V.W. et al.

Quelle: Free Radical Biology & Medicine. May2025, Vol. 232, p128-141. 14p.

Schlagwörter: *SYNAPTIC vesicles, *KNOCKOUT mice, *ALZHEIMER'S disease, *TAU proteins, *CYCLOPHILINS