Suchergebnisse - "KLEBSIELLA pneumoniae"

Multidrug resistant hypervirulent ST307 clone from genomic surveillance of extended spectrum beta-lactamase-producing Klebsiella pneumoniae species complex in East Africa.

Autoren: Kidenya BR Sserwadda I Kanyerezi S et al.

Quelle: BMC microbiology [BMC Microbiol] 2025 Nov 17; Vol. 25 (1), pp. 755. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2180 (Electronic) Linking ISSN: 14712180 NLM ISO Abbreviation: BMC Microbiol Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/isolation & purification , Klebsiella pneumoniae*/enzymology , beta-Lactamases*/genetics , beta-Lactamases*/metabolism , Drug Resistance, Multiple, Bacterial*/genetics , Klebsiella Infections*/microbiology , Klebsiella Infections*/epidemiology, Humans ; Whole Genome Sequencing ; Uganda/epidemiology ; Anti-Bacterial Agents/pharmacology ; Tanzania/epidemiology ; Microbial Sensitivity Tests ; Genome, Bacterial ; Virulence/genetics ; Male ; Virulence Factors/genetics ; Female

Structural elucidation and serological studies of emerging Klebsiella pneumoniae capsular polysaccharides K102 and K112.

Autoren: Ravenscroft N Nonne F Belciug GF et al.

Quelle: Carbohydrate polymers [Carbohydr Polym] 2025 Dec 15; Vol. 370, pp. 124385. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/chemistry , Klebsiella pneumoniae*/immunology , Polysaccharides, Bacterial*/chemistry , Polysaccharides, Bacterial*/immunology , Bacterial Capsules*/chemistry , Bacterial Capsules*/immunology, Animals ; Rabbits ; Humans ; Antigens, Bacterial/chemistry ; Antigens, Bacterial/immunology

Comprehensive genome analysis of MDR Klebsiella pneumoniae in influent and effluent of a selected wastewater treatment plant.

Autoren: Mabeo OR van Niekerk B Olanrewaju OS et al.

Quelle: Scientific reports [Sci Rep] 2025 Dec 03; Vol. 15 (1), pp. 43061. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/isolation & purification , Klebsiella pneumoniae*/pathogenicity , Wastewater*/microbiology , Genome, Bacterial* , Drug Resistance, Multiple, Bacterial*/genetics, Whole Genome Sequencing ; Anti-Bacterial Agents/pharmacology ; Virulence Factors/genetics ; Water Purification ; Plasmids/genetics

Cytochrome bd-II oxidase CyxA promotes the pathogenicity of Klebsiella pneumoniae by resisting oxidative stress.

Autoren: Xiao X Song G Lu H et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2590244. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress* , Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/enzymology , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/drug effects , Bacterial Proteins*/genetics , Bacterial Proteins*/metabolism, Animals ; Mice ; Hydrogen Peroxide/pharmacology ; Hydrogen Peroxide/metabolism ; Klebsiella Infections/microbiology ; Klebsiella Infections/pathology ; Virulence ; Nitric Oxide/metabolism ; Reactive Oxygen Species/metabolism ; Disease Models, Animal ; Gene Deletion ; Virulence Factors/metabolism ; Virulence Factors/genetics ; Female

Rectal Carriage of Sequence Type 307 Klebsiella pneumoniae High-Risk Clone Harboring Multiple Carbapenemase Genes in Community Hospitals Gauteng, South Africa.

Autoren: Salvador-Oke KT Pitout J Peirano G et al.

Quelle: MicrobiologyOpen [Microbiologyopen] 2025 Dec; Vol. 14 (6), pp. e70152.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101588314 Publication Model: Print Cited Medium: Internet ISSN: 2045-8827 (Electronic) Linking ISSN: 20458827 NLM ISO Abbreviation: Microbiologyopen Subsets: MEDLINE

MeSH-Schlagworte: beta-Lactamases*/genetics , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/isolation & purification , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/enzymology , Klebsiella pneumoniae*/classification , Bacterial Proteins*/genetics , Klebsiella Infections*/microbiology , Klebsiella Infections*/epidemiology , Rectum*/microbiology , Carrier State*/microbiology , Carrier State*/epidemiology, South Africa/epidemiology ; Humans ; Plasmids/genetics ; Microbial Sensitivity Tests ; Hospitals, Community ; Anti-Bacterial Agents/pharmacology ; Male ; Female ; Middle Aged ; Carbapenem-Resistant Enterobacteriaceae/genetics ; Adult ; Aged

Characterization and therapeutic efficacy of phage p9676 against epidemic ST11-KL64 Klebsiella pneumoniae: Insights from genomic analysis and in vivo studies.

Autoren: Zhao Y Wen Y Gu L et al.

Quelle: Microbiological research [Microbiol Res] 2025 Dec; Vol. 301, pp. 128298. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: G. Fischer Country of Publication: Germany NLM ID: 9437794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0623 (Electronic) Linking ISSN: 09445013 NLM ISO Abbreviation: Microbiol Res Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/virology , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/drug effects , Klebsiella Infections*/therapy , Klebsiella Infections*/microbiology , Bacteriophages*/genetics , Bacteriophages*/isolation & purification , Bacteriophages*/ultrastructure , Bacteriophages*/physiology , Bacteriophages*/classification , Phage Therapy*/methods, Animals ; Mice ; Genome, Viral ; Genomics ; Humans ; Anti-Bacterial Agents/pharmacology ; Sewage/virology ; Drug Resistance, Multiple, Bacterial ; Base Composition ; Female

Association between Type IV-A CRISPR/Cas system and plasmid-mediated transmission of carbapenemase genes in Klebsiella pneumoniae.

Autoren: Long J Wu J Xi Y et al.

Quelle: Microbiological research [Microbiol Res] 2025 Dec; Vol. 301, pp. 128297. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: G. Fischer Country of Publication: Germany NLM ID: 9437794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0623 (Electronic) Linking ISSN: 09445013 NLM ISO Abbreviation: Microbiol Res Subsets: MEDLINE

MeSH-Schlagworte: beta-Lactamases*/genetics , Plasmids*/genetics , Bacterial Proteins*/genetics , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/enzymology , Klebsiella pneumoniae*/drug effects , CRISPR-Cas Systems*/genetics , Gene Transfer, Horizontal*, Humans ; Klebsiella Infections/microbiology ; Genome, Bacterial

Two novel lytic bacteriophages with antibiofilm activity against carbapenem-resistant Klebsiella pneumoniae infections.

Autoren: Zhang J Sun X Zeng P et al.

Quelle: Infection [Infection] 2025 Dec; Vol. 53 (6), pp. 2587-2600. Date of Electronic Publication: 2025 Jul 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Heidelberg Country of Publication: Germany NLM ID: 0365307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0973 (Electronic) Linking ISSN: 03008126 NLM ISO Abbreviation: Infection Subsets: MEDLINE

MeSH-Schlagworte: Biofilms*/growth & development , Biofilms*/drug effects , Bacteriophages*/physiology , Bacteriophages*/isolation & purification , Bacteriophages*/genetics , Bacteriophages*/classification , Klebsiella pneumoniae*/virology , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/physiology , Klebsiella Infections*/therapy , Klebsiella Infections*/microbiology , Phage Therapy*/methods , Carbapenem-Resistant Enterobacteriaceae*/virology, Animals ; Carbapenems/pharmacology ; Sewage/virology ; Anti-Bacterial Agents/pharmacology ; Genome, Viral ; Moths/microbiology

Structural and functional features of Klebsiella pneumoniae capsular degradation by the phage depolymerase KP32gp38: implications for vaccination.

Autoren: Napolitano V Privitera M Drulis-Kawa Z et al.

Quelle: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107596. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/metabolism , Klebsiella pneumoniae*/virology , Klebsiella pneumoniae*/immunology , Klebsiella pneumoniae*/enzymology , Bacterial Capsules*/metabolism , Glycoside Hydrolases*/metabolism , Glycoside Hydrolases*/chemistry , Bacteriophages*/enzymology, Humans ; Dendritic Cells/immunology ; Crystallography, X-Ray ; Models, Molecular ; Vaccination

Siderophores and beyond: A comprehensive review of iron acquisition in Klebsiella pneumoniae .

Autoren: Lan P Lu Y Fu Y et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2550621. Date of Electronic Publication: 2025 Sep 03.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/metabolism , Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/genetics , Iron*/metabolism , Siderophores*/metabolism, Humans ; Klebsiella Infections/microbiology ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics ; Animals ; Membrane Proteins ; Repressor Proteins

Enhancement of virulence related to polymyxin resistance caused by CrrB mutation in a hypervirulent KPC-2-producing Klebsiella pneumoniae belonging to KL2-ST65 clone.

Autoren: Quan J Zhou M Liao W et al.

Quelle: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107641. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/isolation & purification , beta-Lactamases*/genetics , beta-Lactamases*/metabolism , Anti-Bacterial Agents*/pharmacology , Klebsiella Infections*/microbiology , Klebsiella Infections*/drug therapy , Polymyxins*/pharmacology , Bacterial Proteins*/genetics , Drug Resistance, Bacterial*/genetics, Humans ; Animals ; Virulence/genetics ; Microbial Sensitivity Tests ; Mutation ; Moths/microbiology ; Plasmids/genetics ; Carbapenems/pharmacology ; Whole Genome Sequencing ; Disease Models, Animal

Exogenous proline promotes serum killing of Klebsiella pneumoniae .

Autoren: Kou TS Shang YY Zhang QC et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2545558. Date of Electronic Publication: 2025 Aug 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/immunology , Klebsiella pneumoniae*/metabolism , Klebsiella Infections*/microbiology , Klebsiella Infections*/drug therapy , Klebsiella Infections*/immunology , Proline*/pharmacology , Blood Bactericidal Activity*/drug effects, Animals ; Mice ; Humans ; Complement System Proteins/immunology ; Complement System Proteins/metabolism ; Metabolomics ; Disease Models, Animal ; Female ; Metabolic Networks and Pathways

Iron metabolism contributes to virulence by enhancing serum resistance in the emerging high-risk clone ST15 CRKP.

Autoren: Chen J Li H Li F et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2569700. Date of Electronic Publication: 2025 Oct 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Iron*/metabolism , Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/metabolism , Klebsiella pneumoniae*/drug effects , Klebsiella Infections*/microbiology , Carbapenem-Resistant Enterobacteriaceae*/pathogenicity , Carbapenem-Resistant Enterobacteriaceae*/genetics , Carbapenem-Resistant Enterobacteriaceae*/metabolism, Humans ; Virulence/genetics ; Whole Genome Sequencing ; Virulence Factors/genetics ; China ; Female ; Male

Molecular characterisation of two novel KPC variants mediating ceftazidime-avibactam resistance in ST11 Klebsiella pneumoniae.

Autoren: Guo T Ding L Shen S et al.

Quelle: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107642. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

MeSH-Schlagworte: Ceftazidime*/pharmacology , Azabicyclo Compounds*/pharmacology , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/isolation & purification , Klebsiella pneumoniae*/enzymology , beta-Lactamases*/genetics , beta-Lactamases*/metabolism , Anti-Bacterial Agents*/pharmacology , Drug Resistance, Multiple, Bacterial*/genetics, Humans ; Drug Combinations ; Microbial Sensitivity Tests ; Klebsiella Infections/microbiology ; Klebsiella Infections/drug therapy ; Whole Genome Sequencing ; Bacterial Proteins/genetics ; Mutation

Antimicrobial resistance in hypermucoviscous and non-hypermucoviscous Klebsiella pneumoniae : a systematic review and meta-analysis.

Autoren: Namikawa H Oinuma KI Kaneko Y et al.

Quelle: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2438657. Date of Electronic Publication: 2024 Dec 16.

Publikationsart: Systematic Review; Meta-Analysis; Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/isolation & purification , Klebsiella Infections*/microbiology , Klebsiella Infections*/epidemiology , Anti-Bacterial Agents*/pharmacology , beta-Lactamases*/metabolism , beta-Lactamases*/genetics, Humans ; Microbial Sensitivity Tests ; Carbapenems/pharmacology ; Drug Resistance, Bacterial

A pharmacometric model assessing the in vitro synergistic effect of a bacteriophage-polymyxin B combination in a clinical multidrug-resistant Klebsiella pneumoniae isolate.

Autoren: Farooq A Nang SC Yu HH et al.

Quelle: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107628. Date of Electronic Publication: 2025 Sep 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/virology , Polymyxin B*/pharmacology , Polymyxin B*/pharmacokinetics , Anti-Bacterial Agents*/pharmacology , Bacteriophages*/physiology , Bacteriophages*/growth & development , Phage Therapy*/methods, Drug Resistance, Multiple, Bacterial ; Klebsiella Infections/therapy ; Klebsiella Infections/microbiology ; Humans ; Microbial Sensitivity Tests ; Microbial Viability/drug effects

Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications.

Autoren: Li L Xu X Cheng P et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2449722. Date of Electronic Publication: 2025 Jan 10.

Publikationsart: Journal Article; Review; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/immunology , Klebsiella Infections*/microbiology , Klebsiella Infections*/immunology, Humans ; Virulence ; Bacterial Outer Membrane/drug effects ; Bacterial Outer Membrane/immunology ; Anti-Bacterial Agents/pharmacology ; Animals ; Drug Resistance, Bacterial ; Extracellular Vesicles/immunology

Fumarate and nitrate reduction regulator (FNR) modulates hypermucoviscosity and virulence in hypervirulent Klebsiella pneumoniae through anaerobic adaptation.

Autoren: Xu Y Guo R Wang R et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2536186. Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/metabolism , Bacterial Proteins*/genetics , Bacterial Proteins*/metabolism, Virulence ; Animals ; Anaerobiosis ; Gene Expression Regulation, Bacterial ; Adaptation, Physiological ; Mice ; Klebsiella Infections/microbiology ; Humans ; Biofilms/growth & development ; Fumarates/metabolism ; Female ; Nitrates/metabolism ; Virulence Factors/genetics

The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae in the inflamed gut.

Autoren: Xie J Wang H Ma R et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2474185. Date of Electronic Publication: 2025 Mar 11.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/growth & development , Klebsiella pneumoniae*/pathogenicity , Klebsiella pneumoniae*/enzymology , Klebsiella pneumoniae*/metabolism , Nitrate Reductase*/metabolism , Nitrate Reductase*/genetics , Molybdenum*/metabolism , Klebsiella Infections*/microbiology , Bacterial Proteins*/genetics , Bacterial Proteins*/metabolism , Intestines*/microbiology , Inflammatory Bowel Diseases*/microbiology , Inflammatory Bowel Diseases*/chemically induced , Carrier Proteins*/metabolism , Carrier Proteins*/genetics, Animals ; Mice ; Nitrates/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; Dextran Sulfate ; Female

Phages adapt to recognize an O-antigen polysaccharide site by mutating the "backup" tail protein ORF59, enabling reinfection of phage-resistant Klebsiella pneumoniae .

Autoren: Li P Ma W Cheng J et al.

Quelle: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2455592. Date of Electronic Publication: 2025 Feb 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

MeSH-Schlagworte: Klebsiella pneumoniae*/virology , Klebsiella pneumoniae*/genetics , O Antigens*/metabolism , O Antigens*/chemistry , Bacteriophages*/genetics , Bacteriophages*/physiology , Viral Tail Proteins*/genetics , Viral Tail Proteins*/metabolism, Mutation ; Klebsiella Infections/microbiology ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Virus Attachment ; Open Reading Frames