Search Results - "Islets of Langerhans immunology"

tRNA-derived fragments in T lymphocyte–beta cell crosstalk and in type 1 diabetes pathogenesis in NOD mice

Authors: Brozzi, F. Jacovetti, C. Cosentino, C. et al.

Source: Diabetologia
Diabetologia, vol. 67, no. 10, pp. 2260-2274

Subject Terms: CD4-Positive T-Lymphocytes, 0301 basic medicine, 0303 health sciences, RNA, Untranslated, T-Lymphocytes, Apoptosis, Article, Mice, Islets of Langerhans, Extracellular Vesicles, 03 medical and health sciences, Diabetes Mellitus, Type 1, RNA, Transfer, Mice, Inbred NOD, Insulin-Secreting Cells, Animals, Diabetes Mellitus, Type 1/immunology, Diabetes Mellitus, Type 1/metabolism, Diabetes Mellitus, Type 1/genetics, Insulin-Secreting Cells/metabolism, RNA, Transfer/genetics, RNA, Transfer/metabolism, Female, CD4-Positive T-Lymphocytes/metabolism, CD4-Positive T-Lymphocytes/immunology, Islets of Langerhans/metabolism, Islets of Langerhans/immunology, Extracellular Vesicles/metabolism, T-Lymphocytes/immunology, T-Lymphocytes/metabolism, RNA, Untranslated/genetics, Autoimmunity, Extracellular vesicles, Insulin, Pancreatic islet

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38967669
https://serval.unil.ch/notice/serval:BIB_BF3CD8D4736F
https://serval.unil.ch/resource/serval:BIB_BF3CD8D4736F.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_BF3CD8D4736F9

Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic

Authors: Zeller, Ivo Weiss, Andreas Arnolds, Stefanie et al.

Source: Infection

Subject Terms: Male, 0301 basic medicine, RESPIRATORY-INFECTIONS, Research, Infection, Type 1 diabetes, Autoimmunity, COVID-19, 4202 Epidemiology, SARS-COV-2 INFECTION, Microbiology, DISEASE, 1117 Public Health and Health Services, Islets of Langerhans, 03 medical and health sciences, Risk Factors, COXSACKIEVIRUS B1, Humans, Pandemics, Autoantibodies, 0303 health sciences, Science & Technology, SARS-CoV-2, Incidence, 3202 Clinical sciences, Infant, 1103 Clinical Sciences, ASSOCIATION, ddc, 3. Good health, GPPAD Study Group, Infectious Diseases, Diabetes Mellitus, Type 1, Child, Preschool, BETA-CELL AUTOIMMUNITY, Female, Life Sciences & Biomedicine, Female [MeSH], Diabetes Mellitus, Type 1/epidemiology [MeSH], COVID-19/immunology [MeSH], Autoantibodies/blood [MeSH], Humans [MeSH], Incidence [MeSH], Risk Factors [MeSH], Pandemics [MeSH], Islets of Langerhans/immunology [MeSH], Infant [MeSH], Male [MeSH], SARS-CoV-2/immunology [MeSH], Diabetes Mellitus, Type 1/immunology [MeSH], COVID-19/epidemiology [MeSH], Child, Preschool [MeSH]

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/38874748
https://ora.ox.ac.uk/objects/uuid:77a3cf19-d7cb-4972-9274-0d0cc57680d3
https://doi.org/10.1007/s15010-024-02312-y
https://lirias.kuleuven.be/handle/20.500.12942/744301
https://doi.org/10.1007/s15010-024-02312-y
https://repository.publisso.de/resource/frl:6502151
https://mediatum.ub.tum.de/1770318

Extracellular vesicles derived from stressed beta cells mediate monocyte activation and contribute to islet inflammation

Authors: Mette C. Dekkers Joost M. Lambooij Xudong Pu et al.

Source: Front Immunol
Frontiers in Immunology, Vol 15 (2024)

Subject Terms: 0301 basic medicine, type 1 diabetes, Immunology, Unfolded Protein Response/immunology, er stress, Monocytes, Cell Line, Extracellular Vesicles, Islets of Langerhans, 03 medical and health sciences, Insulin-Secreting Cells/metabolism, Insulin-Secreting Cells, Diabetes Mellitus, Islets of Langerhans/immunology, Humans, Animals, Endoplasmic Reticulum Stress/immunology, Endoplasmic Reticulum Chaperone BiP, Inflammation, 0303 health sciences, Type 1/immunology, Monocytes/immunology, Extracellular Vesicles/metabolism, Inflammation/immunology, RC581-607, Endoplasmic Reticulum Stress, 3. Good health, MicroRNAs/genetics, MicroRNAs, Diabetes Mellitus, Type 1, inflammation, Unfolded Protein Response, Immunologic diseases. Allergy, extracellular vesicles, monocytes, Signal Transduction

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/39114661
https://doaj.org/article/2b3c885eac0a4db1b569f2a73fe0eacb
https://research.rug.nl/en/publications/36dbe57d-fc67-4d57-ba20-eeb2196790c8
https://doi.org/10.3389/fimmu.2024.1393248
https://hdl.handle.net/11370/36dbe57d-fc67-4d57-ba20-eeb2196790c8
https://hdl.handle.net/1887/4214964

Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes

Authors: Phillip, Moshe Achenbach, Peter Addala, Ananta et al.

Contributors: Phillip, Moshe Achenbach, Peter Addala, Ananta et al.

Source: Diabetologia

Subject Terms: YOUNG-CHILDREN, Consensus, DISEASE-MODIFYING THERAPY, Consensus Report, Pediatrics, C-PEPTIDE, 1117 Public Health and Health Services, Diabetic Ketoacidosis, Endocrinology & Metabolism, Islets of Langerhans, Disease Progression [MeSH], Autoantibodies/blood [MeSH], Diabetic Ketoacidosis/diagnosis [MeSH], Humans [MeSH], Prevention, Type 1 diabetes, Autoantibodies/immunology [MeSH], Islets of Langerhans/immunology [MeSH], Glucose monitoring, Autoantibodies, Diabetes Mellitus, Type 1/immunology [MeSH], Diabetes Mellitus, Type 1/diagnosis [MeSH], Diabetic Ketoacidosis/immunology [MeSH], Consensus [MeSH], CLINICAL CHARACTERISTICS, GLYCEMIC CONTROL, Medicine and Health Sciences, Humans, GENERAL-POPULATION, Science & Technology, ENVIRONMENTAL DETERMINANTS, 3202 Clinical sciences, 1103 Clinical Sciences, 16. Peace & justice, 1ST 2 YEARS, ddc, 3. Good health, 4206 Public health, Diabetes Mellitus, Type 1, Disease Progression, BETA-CELL AUTOIMMUNITY, 1114 Paediatrics and Reproductive Medicine, PSYCHOLOGICAL IMPACT, Life Sciences & Biomedicine

File Description: application/msword; application/pdf; application/zip; text/xml

Access URL: https://pubmed.ncbi.nlm.nih.gov/38912694
https://pubmed.ncbi.nlm.nih.gov/38910151
https://repository.publisso.de/resource/frl:6499727
https://www.repository.cam.ac.uk/handle/1810/371853
https://doi.org/10.2337/dci24-0042
https://doi.org/10.17863/cam.110896
https://mediatum.ub.tum.de/doc/1770873/document.pdf

Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets.

Authors: Lohmann, C. Schäfer, N. von Lukowicz, T. et al.

Subject Terms: Animals, Apolipoproteins E/deficiency, Apolipoproteins E/genetics, Atherosclerosis/genetics, Atherosclerosis/immunology, Blood Glucose/metabolism, Body Weight, Connective Tissue/immunology, Connective Tissue/pathology, Cytokines/blood, Disease Models, Animal, Fatty Liver/immunology, Fatty Liver/pathology, Hypercholesterolemia/complications, Hypercholesterolemia/genetics, Inflammation/genetics, Inflammation/immunology, Inflammation Mediators/blood, Insulin/blood, Intra-Abdominal Fat/immunology, Intra-Abdominal Fat/pathology, Islets of Langerhans/immunology, Islets of Langerhans/pathology, Liver/immunology, Liver/pathology, Macrophages/immunology, Male, Mice, Inbred C57BL

Relation: Atherosclerosis; 1879-1484[electronic], 0021-9150[linking]; https://iris.unil.ch/handle/iris/89518; serval:BIB_1AFA54F417D1; 000273566700012

Availability: https://iris.unil.ch/handle/iris/89518
https://doi.org/10.1016/j.atherosclerosis.2009.05.004

BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis

Authors: Luther, S. A. Lopez, T. Bai, W. et al.

Subject Terms: Animals B-Lymphocytes/*immunology/pathology Chemotactic Factors/immunology Islets of Langerhans/*immunology/pathology Lymphoid Tissue/immunology/pathology Lymphotoxin-alpha/*immunology Mice Mice, Transgenic Receptors, Chemokine Receptors, Cytokine/*immunology

Relation: Immunity; https://iris.unil.ch/handle/iris/247636; serval:BIB_EDF31F9EA9F3; 000087356400003

Availability: https://iris.unil.ch/handle/iris/247636
https://doi.org/10.1016/S1074-7613(00)80199-5

Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes.

Authors: Wang, B. André, I. Gonzalez, A. et al.

Subject Terms: Animals, Antigen-Presenting Cells/immunology, Diabetes Mellitus, Type 1/etiology, Type 1/immunology, Female, Interferon-gamma/physiology, Islets of Langerhans/immunology, Male, Mice, Inbred NOD, Mutant Strains, Transgenic, Receptors, Antigen, T-Cell/genetics, T-Cell/physiology, Interferon/genetics, Interferon/physiology, T-Lymphocytes/immunology

Relation: Proceedings of the National Academy of Sciences; https://iris.unil.ch/handle/iris/200785; serval:BIB_6EF7F1FB8F37; A1997YK82500088; 9391115

Availability: https://iris.unil.ch/handle/iris/200785
https://doi.org/10.1073/pnas.94.25.13844

Quantitative temporal analysis of pancreatic islet T lymphocyte and macrophage infiltration heralded by serum IgE in congenic BioBreeding (BB) Gimap5 -/ - rats at risk for insulitis and acute onset diabetes.

Authors: Jönsson, Josefine Faxius, Linda Tångrot, Jeanette et al.

Source: Inflammation Research; 74(1), no 134 (2025) ; ISSN: 1420-908X

Subject Terms: Endocrinology and Diabetes, Animals, Immunoglobulin E/blood, Macrophages/immunology, Islets of Langerhans/immunology, T-Lymphocytes/immunology, Diabetes Mellitus, Type 1/immunology, Male, Rats, Inbred BB, Insulin/metabolism, Prediabetic State/immunology, Glucagon/metabolism, Congenic

Relation: pmid:41042382; scopus:105017719629

Availability: https://lup.lub.lu.se/record/7c431e9c-95ae-4b1f-b30c-6c1e2c904371
https://doi.org/10.1007/s00011-025-02101-9

Accelerated Progression to Type 1 Diabetes in the Presence of HLA-A*24 and -B*18 Is Restricted to Multiple Islet Autoantibody–Positive Individuals With Distinct HLA-DQ and Autoantibody Risk Profiles

Authors: Eric V. Balti Daniel Pipeleers Kristina Casteels et al.

Contributors: Eric V. Balti Daniel Pipeleers Kristina Casteels et al.

Source: Diabetes Care

Subject Terms: Adult, Male, Science et gestion hospitalières, HLA-B18 Antigen/genetics, Child, preschool, Adolescent, Genotype, HLA-B18 Antigen, Insulin Antibodies, HLA-A24 Antigen, Autoimmunity, Santé publique, HLA-DQ Antigens/genetics, Insulin Antibodies/blood, Islets of Langerhans, 03 medical and health sciences, Autres spécialisations médicales et paramédicales, 0302 clinical medicine, Métabolisme, HLA-DQ Antigens, Islets of Langerhans/immunology, risk factors, Humans, Genetic Predisposition to Disease, Registries, Child, Autoantibodies, Diabétologie, Infant, Newborn, Infant, Diabetes Mellitus, Type 1/blood, Endocrinologie, 3. Good health, Médecine interne, Diabetes Mellitus, Type 1, Child, Preschool, Autoimmunity/genetics, Disease Progression, young adult, Female, HLA-A24 Antigen/genetics, Autoantibodies/blood

File Description: 1 full-text file(s): application/pdf

Access URL: https://care.diabetesjournals.org/content/diacare/41/5/1076.full.pdf
https://pubmed.ncbi.nlm.nih.gov/29545461
https://khepri-node.dev.meta-infra.org/papers/accelerated-progression-to-type-1-diabetes-in-the/29545461
https://care.diabetesjournals.org/content/41/5/1076
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/272869/Details
https://europepmc.org/article/MED/29545461
http://care.diabetesjournals.org/content/41/5/1076
https://pubmed.ncbi.nlm.nih.gov/29545461/
https://biblio.vub.ac.be/vubir/accelerated-progression-to-type-1-diabetes-in-the-presence-of-hlaa24-and-b18-is-restricted-to-multipleislet-autoantibodypositive-individuals-with-distinct-hladq-and-autoantibody-risk-profiles(cc7cb56a-54eb-4b14-9750-ad8d8a79d720).html
https://doi.org/10.2337/dc17-2462
https://hdl.handle.net/20.500.14017/cc7cb56a-54eb-4b14-9750-ad8d8a79d720

Longitudinal plasma metabolic profiles, infant feeding, and islet autoimmunity in the MIDIA study: Longitudinal metabolic profiles in MIDIA

Authors: Jørgenrud, Benedicte Stene, Lars C. Tapia, German et al.

Source: Pediatric Diabetes. 18:111-119

Subject Terms: Male, 0301 basic medicine, Type 1/etiology, Autoimmunity, Islets of Langerhans, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Feeding Behavior/physiology, Risk Factors, Diabetes Mellitus, Islets of Langerhans/immunology, Humans, Longitudinal Studies, Preschool, Child, Infant Nutritional Physiological Phenomena, 2. Zero hunger, 0303 health sciences, Norway, 4. Education, ta1182, Infant, Newborn, Infant, ta3142, Feeding Behavior, Newborn, 3. Good health, Breast Feeding, Diabetes Mellitus, Type 1, Case-Control Studies, Child, Preschool, Metabolome, Female, Blood Chemical Analysis

Access URL: https://pubmed.ncbi.nlm.nih.gov/26791677
http://juuli.fi/Record/0281760717
https://doi.org/10.1111/pedi.12360
https://cris.vtt.fi/en/publications/0a21fe90-e847-4d86-92fc-a361d04b44d4
https://doi.org/10.1111/pedi.12360
https://www.ncbi.nlm.nih.gov/pubmed/26791677
https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.12360
http://www.diva-portal.org/smash/record.jsf?pid=diva2:1136174
http://europepmc.org/abstract/MED/26791677

Antibodies to oxidized insulin improve prediction of type 1 diabetes in children with positive standard islet autoantibodies.

Authors: Strollo, Rocky Vinci, Chiara Napoli, Nicola et al.

Source: Diabetes/metabolism research and reviews, 35 (4

Subject Terms: Sciences bio-médicales et agricoles, Autoantibodies -- blood -- immunology, Biomarkers -- blood, Blood Glucose -- analysis, Child, Preschool, Diabetes Mellitus, Type 1 -- blood -- diagnosis -- immunology, Female, Follow-Up Studies, Humans, Insulin Antibodies -- immunology, Insulin, Regular, Human -- chemistry -- immunology, Islets of Langerhans -- immunology, Longitudinal Studies, Male, Oxidation-Reduction, Prognosis, Prospective Studies, Protein Processing, Post-Translational, biomarker, insulin autoantibodies, posttranslational modifications, prediction, type 1 diabetes

File Description: 1 full-text file(s): application/pdf

Relation: uri/info:doi/10.1002/dmrr.3132; uri/info:pmid/30693639; https://dipot.ulb.ac.be/dspace/bitstream/2013/337453/3/DMRR.pdf

Availability: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/337453
https://dipot.ulb.ac.be/dspace/bitstream/2013/337453/3/DMRR.pdf

Antibodies to oxidized insulin improve prediction of type 1 diabetes in children with positive standard islet autoantibodies

Authors: Ernesto Maddaloni Nicola Napoli Rocky Strollo et al.

Source: Diabetes/Metabolism Research and Reviews. 35

Subject Terms: Blood Glucose, Male, 0301 basic medicine, type 1 diabetes, Insulin Antibodies, insulin autoantibodies, Biomarkers -- blood, biomarker, posttranslational modifications, prediction, Insulin Antibodies -- immunology, Human -- chemistry -- immunology, Islets of Langerhans, 03 medical and health sciences, 0302 clinical medicine, Insulin, Regular, Human, Diabetes Mellitus, Insulin, Humans, Type 1 -- blood -- diagnosis -- immunology, Longitudinal Studies, Prospective Studies, Preschool, Child, Protein Processing, Regular, Autoantibodies, Post-Translational, Autoantibodies -- blood -- immunology, Blood Glucose -- analysis, Sciences bio-médicales et agricoles, Prognosis, 3. Good health, Diabetes Mellitus, Type 1, Child, Preschool, Female, Islets of Langerhans -- immunology, Oxidation-Reduction, Protein Processing, Post-Translational, Biomarkers, Follow-Up Studies

File Description: application/pdf; 1 full-text file(s): application/pdf

Access URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/337453/3/DMRR.pdf
https://pubmed.ncbi.nlm.nih.gov/30693639
https://moh-it.pure.elsevier.com/en/publications/antibodies-to-oxidized-insulin-improve-prediction-of-type-1-diabe
https://www.ncbi.nlm.nih.gov/pubmed/30693639
https://onlinelibrary.wiley.com/doi/10.1002/dmrr.3132
https://europepmc.org/article/MED/30693639
https://pubmed.ncbi.nlm.nih.gov/30693639/
http://www.diva-portal.org/smash/record.jsf?pid=diva2:1342283

Relationship between islet autoantibody status and the clinical characteristics of children and adults with incident type 1 diabetes in a UK cohort

Source: 2018, 'Relationship between islet autoantibody status and the clinical characteristics of children and adults with incident type 1 diabetes in a UK cohort', BMJ open, vol. 8, no. 4, pp. e020904. https://doi.org/10.1136/bmjopen-2017-020904

Subject Terms: Adolescent, Adult, Autoantibodies/analysis, Child, Preschool, Cohort Studies, Diabetes Mellitus, Type 1/immunology, England, Female, Humans, Islets of Langerhans/immunology, Male, Wales

Availability: https://kclpure.kcl.ac.uk/portal/en/publications/b3877d19-11c0-4603-9779-57e459d72b8b
https://doi.org/10.1136/bmjopen-2017-020904

The Potential of Endothelial Colony-Forming Cells to Improve Early Graft Loss after Intraportal Islet Transplantation

Authors: Kyong Soo Park Hakmo Lee Hye Seung Jung et al.

Contributors: Kyong Soo Park Hakmo Lee Hye Seung Jung et al.

Source: Cell Transplantation, Vol 23 (2014)

Subject Terms: Blood Glucose, Graft Rejection, Swine, Nude, Islets of Langerhans Transplantation, Tumor Necrosis Factor-alpha/analysis, Endothelial progenitor cell, Islets of Langerhans Transplantation/methods, Mice, 0302 clinical medicine, HMGB1 Protein, High-mobility group box 1 (HMGB1), Cells, Cultured, Heterologous, Cultured, Stem Cells, Inflammation/immunology, Stem Cells/immunology, 3. Good health, Early graft loss, Medicine, Graft Rejection/prevention & control, Islets of Langerhans Transplantation/immunology, Cells, Transplantation, Heterologous, Mice, Nude, Islet transplantation (ITx), Diabetes Mellitus, Experimental, Endothelial colony-forming cells (ECFCs), Islets of Langerhans, 03 medical and health sciences, Diabetes Mellitus, Islets of Langerhans/immunology, Animals, Humans, Inflammation, Transplantation, Instant blood-mediated inflammatory reaction (IBMIR), Tumor Necrosis Factor-alpha, Endothelial Cells/cytology, Endothelial Cells/immunology, Endothelial Cells, Blood Glucose/analysis, Graft Rejection/immunology, Experimental/surgery, Islets of Langerhans/cytology, Coculture Techniques, HMGB1 Protein/analysis, Stem Cells/cytology, Coculture Techniques/methods

File Description: 273~283

Access URL: http://journals.sagepub.com/doi/pdf/10.3727/096368912X661364
https://pubmed.ncbi.nlm.nih.gov/23294520
https://doaj.org/article/71b493198797484080cf333ba6bd0ff0
https://europepmc.org/article/MED/23294520
https://pubmed.ncbi.nlm.nih.gov/23294520/
https://www.ncbi.nlm.nih.gov/pubmed/23294520
https://journals.sagepub.com/doi/10.3727/096368912X661364
https://snucm.elsevierpure.com/en/publications/the-potential-of-endothelial-colony-forming-cells-to-improve-earl
http://journals.sagepub.com/doi/10.3727/096368912X661364

Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β‐cell apoptosis

Authors: Santin Gomez, Izortze Eizirik, Decio L.

Source: Diabetes, Obesity and Metabolism. 15:71-81

Subject Terms: Inflammation, 0301 basic medicine, Insulin-Secreting Cells -- metabolism -- pathology -- physiology, 0303 health sciences, Apoptosis -- genetics, Apoptosis, Autoimmunity, Sciences bio-médicales et agricoles, Inflammation -- genetics -- pathology, Pancreatic β-cells, Candidate genes, 3. Good health, Islets of Langerhans, 03 medical and health sciences, Type 1 diabetes, Diabetes Mellitus, Type 1, Autoimmunity -- genetics, Gene Expression Regulation, Type 1 -- genetics, Insulin-Secreting Cells, Diabetes Mellitus, Cytokines, Humans, Islets of Langerhans -- immunology -- metabolism -- pathology, Genetic Association Studies

File Description: 1 full-text file(s): application/pdf

Access URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dom.12162
https://pubmed.ncbi.nlm.nih.gov/24003923
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/163444/Details
https://dom-pubs.onlinelibrary.wiley.com/doi/full/10.1111/dom.12162
https://www.ncbi.nlm.nih.gov/pubmed/24003923
https://www.onlinelibrary.wiley.com/doi/10.1111/dom.12162
https://onlinelibrary.wiley.com/doi/abs/10.1111/dom.12162
https://europepmc.org/article/MED/24003923

Increased expression of microRNA miR‐326 in type 1 diabetic patients with ongoing islet autoimmunity

Authors: SEBASTIANI G. GRIECO F. A. SPAGNUOLO I. et al.

Contributors: SEBASTIANI G. GRIECO F. A. SPAGNUOLO I. et al.

Source: Diabetes/metabolism research and reviews, 27 (8
Diabetes/Metabolism Research and Reviews

Subject Terms: MiR-326, 0301 basic medicine, Glutamate Decarboxylase -- immunology, Receptor-Like Protein Tyrosine Phosphatases, Autoimmunity, Autoimmunity -- immunology, Islets of Langerhans, 03 medical and health sciences, Type 1 -- blood -- genetics, Diabetes Mellitus, Humans, Receptor-Like Protein Tyrosine Phosphatases, Class 8, Autoantibodies -- immunology, Autoantibodies, MicroRNA, Type 1 diabetes, 0303 health sciences, Glutamate Decarboxylase, Sciences bio-médicales et agricoles, Class 8, Autoantibodie, MicroRNAs -- biosynthesis, 3. Good health, MicroRNAs, Diabetes Mellitus, Type 1, Islets of Langerhans -- immunology, Diabetes Mellitus, Type 1 -- blood -- genetics

File Description: application/pdf; 1 full-text file(s): application/pdf; STAMPA

Access URL: https://pubmed.ncbi.nlm.nih.gov/22069274
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/188696/Details
https://onlinelibrary.wiley.com/doi/abs/10.1002/dmrr.1262
https://pubmed.ncbi.nlm.nih.gov/22069274/
https://www.ncbi.nlm.nih.gov/pubmed/22069274
https://core.ac.uk/display/77545017
https://onlinelibrary.wiley.com/doi/10.1002/dmrr.1262
https://doi.org/10.1002/dmrr.1262
https://hdl.handle.net/11365/32835
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/188669

Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells

Authors: Silva, Diego Daley, Stephen Hogan, Jennifer et al.

Source: Diabetes

Subject Terms: CD4-Positive T-Lymphocytes, 0301 basic medicine, T-Lymphocytes, animal experiment, Receptors, Antigen, T-Cell, Mice, Transgenic, animal cell, cell survival, Transgenic, animal tissue, diabetogenesis, Islets of Langerhans, Mice, 03 medical and health sciences, CD4-Positive T-Lymphocytes/*immunology, Receptors, Diabetes Mellitus, Animals, immunoglobulin G antibody, Type 1/*etiology/immunology, T-Cell/immunology, Autoantibodies, B lymphocyte activation, CD4+ T lymphocyte, B-Lymphocytes, 0303 health sciences, animal model, disease course, Helper-Inducer/immunology, article, B-Lymphocytes/immunology, Islets of Langerhans/*immunology, T-Lymphocytes, Helper-Inducer, 3. Good health, Diabetes Mellitus, Type 1, Antigen, pancreas islet cell antibody, T lymphocyte receptor, Immunology and Transplantation, Keywords: autoantibody, Autoantibodies/immunology

File Description: application/pdf

Access URL: http://diabetes.diabetesjournals.org/content/diabetes/60/8/2102.full.pdf
https://pubmed.ncbi.nlm.nih.gov/21788582
https://digitalcollections.anu.edu.au/handle/1885/37089
https://europepmc.org/abstract/MED/21788582
https://eprints.qut.edu.au/106829/
https://diabetes.diabetesjournals.org/content/diabetes/60/8/2102.full.pdf
https://core.ac.uk/display/83152280
https://cyberleninka.org/article/n/350039

Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes

Authors: M van Lummel Arnaud Zaldumbide Bart O. Roep et al.

Source: Genes & Immunity. 12:415-427

Subject Terms: Male, 0301 basic medicine, Heterozygote, Syndecans, Adolescent, T-Lymphocytes, Thymosin/metabolism, Epitopes, B-Lymphocyte/immunology, Islets of Langerhans, 03 medical and health sciences, 0302 clinical medicine, MHC class II type 1 diabetes HLA-DQ trans-dimer insulin genetic risk autoimmune disease class-ii molecule t-cell responses hla-dq celiac-disease binding characteristics epitope specificity cytokine production unique properties dutch population immune-response, Syndecans/metabolism, HLA-DQ Antigens, Humans, Insulin, Genetic Predisposition to Disease, B-Lymphocytes, Homozygote, Insulin/genetics, Islets of Langerhans/*immunology, Diabetes Mellitus, Type 1/genetics/immunology/*metabolism, 3. Good health, Thymosin, Diabetes Mellitus, Type 1, HLA-DQ Antigens/*genetics, B-Lymphocytes/cytology/immunology, Epitopes, B-Lymphocyte, T-Lymphocytes/cytology/immunology, Protein Binding

Access URL: https://www.nature.com/articles/gene201124.pdf
https://pubmed.ncbi.nlm.nih.gov/21562577
https://europepmc.org/article/MED/21562577
https://pubmed.ncbi.nlm.nih.gov/21562577/
https://www.narcis.nl/publication/RecordID/oai%3Ascholarlypublications.universiteitleiden.nl%3Aitem_3013077
https://www.ncbi.nlm.nih.gov/pubmed/21562577
https://www.nature.com/articles/gene201124.pdf
https://www.nature.com/articles/gene201124
http://olympias.lib.uoi.gr/jspui/handle/123456789/21478
https://hdl.handle.net/1887/118876
https://hdl.handle.net/1887/88124

Histologic Graft Assessment After Clinical Islet Transplantation

Authors: Toso, Christian Isse, Kumiko Demetris, Anthony J. et al.

Source: Transplantation, Vol. 88, No 11 (2009) pp. 1286-1293

Subject Terms: Adult, Graft Rejection, Male, 0301 basic medicine, Time Factors, Islets of Langerhans/immunology/*pathology/*surgery, Islets of Langerhans Transplantation, Biopsy, Needle, Islets of Langerhans, 03 medical and health sciences, Graft Rejection/immunology/pathology, Predictive Value of Tests, Liver/immunology/*pathology/*surgery, Humans, Transplantation, Homologous, Prospective Studies, Ultrasonography, Interventional, 0303 health sciences, ddc:617, Middle Aged, Islets of Langerhans Transplantation/adverse effects, 3. Good health, Diabetes Mellitus, Type 1, Liver, Case-Control Studies, Feasibility Studies, Female, Autopsy, Diabetes Mellitus, Type 1/immunology/pathology/*surgery

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Access URL: https://pubmed.ncbi.nlm.nih.gov/19996928
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https://www.ncbi.nlm.nih.gov/pubmed/19996928
http://europepmc.org/abstract/MED/19996928
https://archive-ouverte.unige.ch/unige:20130
https://archive-ouverte.unige.ch/unige:20130
https://doi.org/10.1097/tp.0b013e3181bc06b0
https://archive-ouverte.unige.ch/unige:20130

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

Authors: Eizirik, Decio L. Colli, Maikel Luis Ortis, Fernanda

Source: Nature Reviews Endocrinology. 5:219-226

Subject Terms: Inflammation, 0301 basic medicine, 0303 health sciences, Inflammation -- physiopathology, Insulin-Secreting Cells -- pathology, Sciences bio-médicales et agricoles, 3. Good health, Islets of Langerhans, 03 medical and health sciences, Diabetes Mellitus, Type 1, Type 1 -- immunology, Insulin-Secreting Cells, Diabetes Mellitus, Type 1 -- physiopathology, Type 1 -- pathology, Insulin-Secreting Cells -- immunology, Animals, Humans, Islets of Langerhans -- immunology, Islets of Langerhans -- pathology

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Access URL: https://pubmed.ncbi.nlm.nih.gov/19352320
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https://europepmc.org/article/MED/19352320
http://www.readcube.com/articles/10.1038/nrendo.2009.21
https://nature.com/articles/nrendo.2009.21
https://www.nature.com/articles/nrendo.2009.21.pdf