Suchergebnisse - "Islands"

CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression.

Autoren: Ganti KP Surjit M

Quelle: Epigenetics [Epigenetics] 2025 Dec; Vol. 20 (1), pp. 2529358. Date of Electronic Publication: 2025 Jul 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2308 (Electronic) Linking ISSN: 15592294 NLM ISO Abbreviation: Epigenetics Subsets: MEDLINE

MeSH-Schlagworte: CpG Islands* , Sp1 Transcription Factor*/metabolism , Sp1 Transcription Factor*/genetics , Promoter Regions, Genetic* , Cytokines*/genetics , Cytokines*/metabolism , DNA Methylation* , DNA Demethylation*, Humans ; Thymic Stromal Lymphopoietin ; Binding Sites ; Epigenesis, Genetic

Genomic islands and plasmid borne antimicrobial resistance genes drive the evolution of high-risk, ST-131 uropathogenic E. coli NS30.

Autoren: Peketi ASK Nagaraja V Bulagonda EP

Quelle: BMC genomics [BMC Genomics] 2025 Nov 19; Vol. 26 (1), pp. 1065. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

MeSH-Schlagworte: Genomic Islands* , Uropathogenic Escherichia coli*/genetics , Uropathogenic Escherichia coli*/drug effects , Uropathogenic Escherichia coli*/pathogenicity , Uropathogenic Escherichia coli*/classification , Plasmids*/genetics , Evolution, Molecular* , Drug Resistance, Bacterial*/genetics, Humans ; Genome, Bacterial ; Drug Resistance, Multiple, Bacterial/genetics ; Phylogeny ; Escherichia coli Infections/microbiology ; Urinary Tract Infections/microbiology ; Genomics ; Virulence Factors/genetics

Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements.

Autoren: You JS Pierce S Liang G et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Oct 28; Vol. 122 (43), pp. e2502963122. Date of Electronic Publication: 2025 Oct 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: CpG Islands*/genetics , DNA Methylation*/genetics , DNA Transposable Elements*/genetics , Regulatory Sequences, Nucleic Acid*/genetics, Humans ; Animals ; Evolution, Molecular ; Transcription Initiation Site ; Genome, Human

Distribution of serogroup and pathogenicity Island markers of uropathogenic Escherichia coli from inpatients in a tertiary care hospital.

Autoren: Malekzadegan Y Abdi A Khashei R

Quelle: BMC research notes [BMC Res Notes] 2025 Oct 22; Vol. 18 (1), pp. 440. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500 (Electronic) Linking ISSN: 17560500 NLM ISO Abbreviation: BMC Res Notes Subsets: MEDLINE

MeSH-Schlagworte: Uropathogenic Escherichia coli*/genetics , Uropathogenic Escherichia coli*/isolation & purification , Uropathogenic Escherichia coli*/pathogenicity , Uropathogenic Escherichia coli*/classification , Tertiary Care Centers* , Escherichia coli Infections*/microbiology , Genomic Islands*/genetics , Urinary Tract Infections*/microbiology, Humans ; Serogroup ; Cross-Sectional Studies ; Retrospective Studies ; Inpatients ; O Antigens/genetics ; Female ; Male

GIS, Remote Sensing and Machine Learning: Data Integration to Support the Management of Coastal Island Ecosystems.

Autoren: Lieske DJ Avery-Gomm S Champagne P et al.

Quelle: Environmental management [Environ Manage] 2025 Oct; Vol. 75 (10), pp. 2625-2646. Date of Electronic Publication: 2025 Jun 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7703893 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1009 (Electronic) Linking ISSN: 0364152X NLM ISO Abbreviation: Environ Manage Subsets: MEDLINE

MeSH-Schlagworte: Machine Learning* , Geographic Information Systems* , Remote Sensing Technology* , Ecosystem* , Islands* , Conservation of Natural Resources*/methods , Environmental Monitoring*/methods, Nova Scotia ; Climate Change

Down-regulation of RBM47 due to diminished activation by forkhead box A1 (FOXA1) and silencing by CpG methylation is associated with epithelial-mesenchymal transition and metastasis of colorectal cancer.

Autoren: Rokavec M Du Y Hermeking H

Quelle: Molecular biomedicine [Mol Biomed] 2025 Dec 03; Vol. 6 (1), pp. 133. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , Epithelial-Mesenchymal Transition*/genetics , DNA Methylation*/genetics , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism , Down-Regulation* , CpG Islands*/genetics , Hepatocyte Nuclear Factor 3-alpha*/metabolism , Hepatocyte Nuclear Factor 3-alpha*/genetics , Gene Silencing*, Humans ; Animals ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Mice ; Neoplasm Metastasis ; Promoter Regions, Genetic ; Prognosis ; Cell Movement/genetics ; Female ; Male

Mendelian randomization analysis of CpG methylation and immune phenotypes in epithelial ovarian cancer outcomes.

Autoren: Li J Luo W Nie D et al.

Quelle: Epigenetics [Epigenetics] 2025 Dec; Vol. 20 (1), pp. 2527145. Date of Electronic Publication: 2025 Jul 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2308 (Electronic) Linking ISSN: 15592294 NLM ISO Abbreviation: Epigenetics Subsets: MEDLINE

MeSH-Schlagworte: DNA Methylation* , Carcinoma, Ovarian Epithelial*/genetics , Carcinoma, Ovarian Epithelial*/immunology , Carcinoma, Ovarian Epithelial*/pathology , CpG Islands* , Ovarian Neoplasms*/genetics , Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/pathology, Humans ; Female ; Mendelian Randomization Analysis ; Quantitative Trait Loci ; Prognosis ; Genome-Wide Association Study ; Phenotype ; Biomarkers, Tumor/genetics

Genomic island-encoded LmiA regulates acid resistance and biofilm formation in enterohemorrhagic Escherichia coli O157:H7.

Autoren: Sun H Jiang L Chen J et al.

Quelle: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2443107. Date of Electronic Publication: 2024 Dec 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH-Schlagworte: Escherichia coli O157*/genetics , Escherichia coli O157*/physiology , Escherichia coli O157*/drug effects , Biofilms*/growth & development , Biofilms*/drug effects , Genomic Islands* , Escherichia coli Proteins*/genetics , Escherichia coli Proteins*/metabolism , Gene Expression Regulation, Bacterial* , Acids*/pharmacology , Acids*/metabolism, Escherichia coli Infections/microbiology ; Humans ; Glutamate Decarboxylase ; Membrane Proteins

Function analysis of LIPI-4 in Listeria monocytogenes reveals a key role of flagella formation in the regulation of virulence.

Autoren: Liu C Ma X Jia B et al.

Quelle: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2543144. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

MeSH-Schlagworte: Listeria monocytogenes*/pathogenicity , Listeria monocytogenes*/genetics , Flagella*/genetics , Flagella*/metabolism , Flagella*/physiology , Genomic Islands* , Virulence Factors*/genetics, Humans ; Virulence/genetics ; Animals ; Mice ; Caco-2 Cells ; RAW 264.7 Cells ; Gene Expression Regulation, Bacterial ; Listeriosis/microbiology ; Cell Line ; Gene Expression Profiling ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Multigene Family

Preventing CpG hypermethylation in oocytes safeguards mouse development.

Autoren: Kawamura YK Ozonov EA Papasaikas P et al.

Quelle: Developmental cell [Dev Cell] 2025 Dec 01; Vol. 60 (23), pp. 3285-3303.e9. Date of Electronic Publication: 2025 Sep 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

MeSH-Schlagworte: Oocytes*/metabolism , Oocytes*/cytology , DNA Methylation*/genetics , Jumonji Domain-Containing Histone Demethylases*/metabolism , Jumonji Domain-Containing Histone Demethylases*/genetics , CpG Islands*/genetics , Embryonic Development*/genetics , F-Box Proteins*/metabolism , F-Box Proteins*/genetics, Animals ; Mice ; Female ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; DNA (Cytosine-5-)-Methyltransferases/genetics ; Histones/metabolism ; DNA Methyltransferase 3A ; Gene Expression Regulation, Developmental ; Oogenesis/genetics ; Histone Demethylases

Genomic islands and molecular mechanisms relating to drug-resistance in Clostridioides ( Clostridium ) difficile PCR ribotype 176.

Autoren: Krutova M Kovarovic V Brajerova M et al.

Quelle: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2482698. Date of Electronic Publication: 2025 Apr 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/pharmacology , Clostridioides difficile*/genetics , Clostridioides difficile*/drug effects , Clostridioides difficile*/isolation & purification , Clostridioides difficile*/classification , Clostridium Infections*/microbiology , Clostridium Infections*/epidemiology , Genomic Islands* , Drug Resistance, Bacterial* , Drug Resistance, Multiple, Bacterial*/genetics, Humans ; Microbial Sensitivity Tests ; Ribotyping ; Multilocus Sequence Typing ; Poland/epidemiology ; Czech Republic/epidemiology ; Methyltransferases/genetics ; Whole Genome Sequencing ; Bacterial Proteins/genetics

Hydrogen sulfide (H 2 S) alleviates diabetic myocardial fibrosis by suppressing pyroptosis via inhibiting DNMT3a-mediated Sestrin2 CpG promoter hypermethylation.

Autoren: Liu Y Yang T Hu H et al.

Quelle: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2025 Dec; Vol. 774, pp. 110605. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

MeSH-Schlagworte: Hydrogen Sulfide*/pharmacology , Pyroptosis*/drug effects , Diabetic Cardiomyopathies*/drug therapy , Diabetic Cardiomyopathies*/metabolism , Diabetic Cardiomyopathies*/pathology , Diabetic Cardiomyopathies*/genetics , DNA Methylation*/drug effects , DNA (Cytosine-5-)-Methyltransferases*/metabolism , DNA (Cytosine-5-)-Methyltransferases*/genetics , Promoter Regions, Genetic*/drug effects , Nuclear Proteins*/genetics , Nuclear Proteins*/metabolism , CpG Islands*/genetics, Animals ; Rats ; Male ; Fibrosis ; Rats, Sprague-Dawley ; DNA Methyltransferase 3A ; Myocardium/pathology ; Myocardium/metabolism ; Signal Transduction/drug effects ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/metabolism ; Sestrins

A qualitative prognostic biomarker for melanoma based on the relative methylation orderings of CpG loci.

Autoren: Huo Y Gao Y Ruan J et al.

Quelle: Epigenetics [Epigenetics] 2025 Dec; Vol. 20 (1), pp. 2487316. Date of Electronic Publication: 2025 Apr 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2308 (Electronic) Linking ISSN: 15592294 NLM ISO Abbreviation: Epigenetics Subsets: MEDLINE

MeSH-Schlagworte: Melanoma*/genetics , Melanoma*/mortality , Melanoma*/immunology , Melanoma*/pathology , DNA Methylation* , Biomarkers, Tumor*/genetics , Skin Neoplasms*/genetics , Skin Neoplasms*/mortality , Skin Neoplasms*/immunology , CpG Islands*, Humans ; Prognosis ; Female ; Male ; Middle Aged ; Melanoma, Cutaneous Malignant

Localization of the origin of transfer for Salmonella genomic island 4 from Salmonella enterica serovar I 4,[5],12:i:.

Autoren: Neupane DP Bearson BL Bearson SMD

Quelle: DNA research : an international journal for rapid publication of reports on genes and genomes [DNA Res] 2025 Dec 01; Vol. 32 (6).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 9423827 Publication Model: Print Cited Medium: Internet ISSN: 1756-1663 (Electronic) Linking ISSN: 13402838 NLM ISO Abbreviation: DNA Res Subsets: MEDLINE

MeSH-Schlagworte: Salmonella enterica*/genetics , Genomic Islands* , Gene Transfer, Horizontal*, Serogroup ; Plasmids/genetics ; Conjugation, Genetic ; Drug Resistance, Multiple, Bacterial

Factors Related to Recruitment and Retention of Doctors on Remote Islands: A Systematic Review.

Autoren: Yamauchi M Watanabe J Kawazuma Y et al.

Quelle: The Tohoku journal of experimental medicine [Tohoku J Exp Med] 2025 Nov 26; Vol. 267 (3), pp. 273-280. Date of Electronic Publication: 2025 May 01.

Publikationsart: Journal Article; Systematic Review

Info zur Zeitschrift: Publisher: Tohoku University Medical Library Country of Publication: Japan NLM ID: 0417355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-3329 (Electronic) Linking ISSN: 00408727 NLM ISO Abbreviation: Tohoku J Exp Med Subsets: MEDLINE

MeSH-Schlagworte: Physicians*/supply & distribution , Islands* , Personnel Selection*, Humans ; Quality of Life

Genomic islands in Pseudomonas encode modular hotspots of defence and anti-defence systems.

Autoren: Garrett SR Tucker SK Pavelka V et al.

Quelle: NAR genomics and bioinformatics [NAR Genom Bioinform] 2025 Nov 19; Vol. 7 (4), pp. lqaf148. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 101756213 Publication Model: eCollection Cited Medium: Internet ISSN: 2631-9268 (Electronic) Linking ISSN: 26319268 NLM ISO Abbreviation: NAR Genom Bioinform Subsets: MEDLINE

MeSH-Schlagworte: Genomic Islands* , Pseudomonas aeruginosa*/genetics , Pseudomonas aeruginosa*/pathogenicity , Pseudomonas aeruginosa*/virology , Pseudomonas*/genetics, Genome, Bacterial ; Virulence Factors/genetics ; Interspersed Repetitive Sequences

RECAP-seq: restriction enzyme-based CpG-methylated fragment amplification for early cancer detection.

Autoren: Shin D Kim T Lee J et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 19; Vol. 15 (1), pp. 40892. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: CpG Islands*/genetics , DNA Methylation* , Early Detection of Cancer*/methods , DNA Restriction Enzymes*/metabolism , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/diagnosis, Humans ; Biomarkers, Tumor/genetics ; Female ; Cell Line, Tumor ; Male

Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization.

Autoren: He L Patkowski JB Wang J et al.

Quelle: Cell [Cell] 2025 Nov 13; Vol. 188 (23), pp. 6636-6653.e17. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

MeSH-Schlagworte: Bacteriophages*/genetics , Bacteriophages*/physiology , Genomic Islands* , Bacteria*/genetics , Bacteria*/virology, Capsid/metabolism

A cyclic di-GMP phosphodiesterase in the VSP-2 island of Vibrio cholerae is regulated by zinc and quorum sensing.

Autoren: Rangarajan AA Ok K Malleck MK et al.

Quelle: MBio [mBio] 2025 Nov 12; Vol. 16 (11), pp. e0227525. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

MeSH-Schlagworte: Vibrio cholerae*/genetics , Vibrio cholerae*/enzymology , Vibrio cholerae*/physiology , Gene Expression Regulation, Bacterial* , Zinc*/metabolism , Genomic Islands* , Quorum Sensing* , Phosphoric Diester Hydrolases*/genetics , Phosphoric Diester Hydrolases*/metabolism, Cyclic GMP/analogs & derivatives ; Cyclic GMP/metabolism ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics

Optimising small island developing states and overseas countries and territories classification for comparative public health research: an alternative methodological approach.

Autoren: Roβkamp DK Huis A Gerstenbluth I et al.

Quelle: BMJ global health [BMJ Glob Health] 2025 Nov 04; Vol. 10 (11). Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101685275 Publication Model: Electronic Cited Medium: Print ISSN: 2059-7908 (Print) Linking ISSN: 20597908 NLM ISO Abbreviation: BMJ Glob Health Subsets: MEDLINE

MeSH-Schlagworte: Public Health* , Islands* , Developing Countries*, Humans ; Global Health