Výsledky vyhľadávania - "Ion Channels"

Beyond hydrodynamics: The role of ion channels in dentine hypersensitivity.

Autori: Sun Y Sanders AM Pashley DH a ďalší

Zdroj: Journal of dentistry [J Dent] 2025 Jun; Vol. 157, pp. 105745. Date of Electronic Publication: 2025 Apr 10.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dentin Sensitivity*/physiopathology , Ion Channels*/physiology, Humans ; Hydrodynamics ; Odontoblasts/physiology ; Transient Receptor Potential Channels/physiology ; Acid Sensing Ion Channels/physiology ; Animals ; Cell Communication/physiology ; Sensory Receptor Cells/physiology

Acid-sensing ion channel 3 in macrophages, but not sensory neurons, mediates development of activity-induced muscle pain.

Autori: Hayashi K Lesnak JB Plumb AN a ďalší

Zdroj: Brain, behavior, and immunity [Brain Behav Immun] 2025 Nov; Vol. 130, pp. 106122. Date of Electronic Publication: 2025 Sep 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Acid Sensing Ion Channels*/metabolism , Acid Sensing Ion Channels*/genetics , Macrophages*/metabolism , Sensory Receptor Cells*/metabolism , Myalgia*/metabolism, Animals ; Mice ; Mice, Knockout ; Muscle, Skeletal/metabolism ; Male ; Mice, Inbred C57BL ; Cytokines/metabolism ; CX3C Chemokine Receptor 1

Celebrating 50 Years of Single-Channel Recording with the Patch Clamp.

Autori: Catacuzzeno L Franciolini F

Zdroj: The Journal of membrane biology [J Membr Biol] 2025 Dec; Vol. 258 (6), pp. 429-445. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article; Historical Article; Review

Informácie o časopise: Publisher: Springer Country of Publication: United States NLM ID: 0211301 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1424 (Electronic) Linking ISSN: 00222631 NLM ISO Abbreviation: J Membr Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Patch-Clamp Techniques*/history , Patch-Clamp Techniques*/methods , Ion Channels*/physiology , Ion Channels*/metabolism, Animals ; History, 20th Century ; Ion Channel Gating ; History, 21st Century ; Humans

The Mutation of piezo1 Weakens the Intermuscular Bones in Zebrafish and Crucian Carp.

Autori: Zhang X Che J Li Z a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 08; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Zebrafish*/genetics , Carps*/genetics , Ion Channels*/genetics , Ion Channels*/metabolism , Mutation* , Zebrafish Proteins*/genetics , Zebrafish Proteins*/metabolism , Bone and Bones*/metabolism , Fish Proteins*/genetics , Fish Proteins*/metabolism, Animals ; CRISPR-Cas Systems

Joint Acidosis and Acid-Sensing Receptors and Ion Channels in Osteoarthritis Pathobiology and Therapy.

Autori: Martin WN Hyde C Yung A a ďalší

Zdroj: Cells [Cells] 2025 Oct 16; Vol. 14 (20). Date of Electronic Publication: 2025 Oct 16.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

Výrazy zo slovníka MeSH: Osteoarthritis*/pathology , Osteoarthritis*/metabolism , Osteoarthritis*/therapy , Acidosis*/metabolism , Acidosis*/pathology , Ion Channels*/metabolism , Joints*/pathology , Joints*/metabolism , Acid Sensing Ion Channels*/metabolism, Humans ; Animals ; Chondrocytes/metabolism

Piezo1-mediated endoplasmic reticulum stress-dependent apoptosis exacerbates intestinal epithelial barrier disruption in necrotizing enterocolitis.

Autori: Wei J Dang D Li Z a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115721. Date of Electronic Publication: 2025 Oct 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endoplasmic Reticulum Stress* , Ion Channels*/metabolism , Ion Channels*/genetics , Enterocolitis, Necrotizing*/metabolism , Enterocolitis, Necrotizing*/pathology , Intestinal Mucosa*/pathology , Intestinal Mucosa*/metabolism, Humans ; Animals ; Apoptosis ; Mice ; Caco-2 Cells ; Mice, Knockout ; Mice, Inbred C57BL ; Male ; Female ; Calcium/metabolism

Mechanosensitive Piezo1 Channels Mediate Diaphragm Fibrosis Induced by Prolonged Mechanical Ventilation.

Autori: Xie D Xiao Y Li X a ďalší

Zdroj: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2025 Dec; Vol. 16 (6), pp. e70136.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ion Channels*/metabolism , Ion Channels*/genetics , Diaphragm*/pathology , Diaphragm*/metabolism , Respiration, Artificial*/adverse effects, Animals ; Rats ; Fibrosis/etiology ; Male ; Disease Models, Animal ; Rats, Sprague-Dawley

Targeting and anchoring the mechanosensitive ion channel Piezo to facilitate its inhibition of axon regeneration.

Autori: Wang Q Miles L Wang S a ďalší

Zdroj: PLoS genetics [PLoS Genet] 2025 Dec 01; Vol. 21 (12), pp. e1011968. Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Výrazy zo slovníka MeSH: Axons*/physiology , Axons*/metabolism , Nerve Regeneration*/genetics , Ion Channels*/genetics , Ion Channels*/metabolism , Drosophila Proteins*/genetics , Drosophila Proteins*/metabolism, Animals ; Mice ; Integrin beta1/genetics ; Integrin beta1/metabolism ; Mechanotransduction, Cellular/genetics ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism ; Sensory Receptor Cells/metabolism ; Spinal Cord Injuries/genetics ; Spinal Cord Injuries/pathology ; Spinal Cord Injuries/metabolism ; Drosophila ; Drosophila melanogaster/genetics ; Humans

Piezo1 negatively regulates proliferation, but enhances mineralization in human cementoblasts.

Autori: Hasegawa T Ouchi T Kurashima R a ďalší

Zdroj: Journal of oral biosciences [J Oral Biosci] 2025 Dec; Vol. 67 (4), pp. 100705. Date of Electronic Publication: 2025 Nov 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101226721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-3865 (Electronic) Linking ISSN: 13490079 NLM ISO Abbreviation: J Oral Biosci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dental Cementum*/cytology , Dental Cementum*/metabolism , Dental Cementum*/physiology , Cell Proliferation* , Ion Channels*/metabolism , Ion Channels*/physiology , Calcification, Physiologic*/physiology, Humans ; Mechanotransduction, Cellular/physiology ; Cells, Cultured ; Calcium Signaling ; Calcium/metabolism ; Pyrazines ; Thiadiazoles

Mechanisms of matrix stiffness affecting calcific aortic valve disease by regulating Piezo1.

Autori: Cao N Cheng S Hu H a ďalší

Zdroj: Atherosclerosis [Atherosclerosis] 2025 Dec; Vol. 411, pp. 120553. Date of Electronic Publication: 2025 Oct 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aortic Valve*/pathology , Aortic Valve*/metabolism , Calcinosis*/genetics , Calcinosis*/metabolism , Calcinosis*/pathology , Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Ion Channels*/metabolism , Ion Channels*/genetics , Aortic Valve Stenosis*/pathology , Aortic Valve Stenosis*/genetics , Aortic Valve Stenosis*/metabolism , Aortic Valve Disease*/metabolism , Aortic Valve Disease*/pathology , Aortic Valve Disease*/genetics, Animals ; Humans ; Disease Models, Animal ; Osteogenesis ; Mice ; Male ; Mice, Knockout ; Cells, Cultured ; Mice, Inbred C57BL ; Mechanotransduction, Cellular ; Elastic Modulus ; Cell Differentiation ; Collagen Type IV/metabolism ; Collagen Type IV/genetics

SCR Disease Name: Aortic Valve, Calcification of

Piezo1 in microglial cells: Implications for neuroinflammation and tumorigenesis.

Autori: Yang B Li Z Li P a ďalší

Zdroj: Channels (Austin, Tex.) [Channels (Austin)] 2025 Dec; Vol. 19 (1), pp. 2492161. Date of Electronic Publication: 2025 Apr 13.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6969 (Electronic) Linking ISSN: 19336950 NLM ISO Abbreviation: Channels (Austin) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Microglia*/metabolism , Microglia*/pathology , Ion Channels*/metabolism , Ion Channels*/genetics , Carcinogenesis*/metabolism , Carcinogenesis*/pathology , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/pathology, Humans ; Animals ; Mechanotransduction, Cellular ; Inflammation/metabolism

Hyperosmolarity-induced activation of PIEZO1 engages detrimental calcium/oxidative stress signaling and adaptive catalase response in renal inner medullary collecting duct (mIMCD 3 ) cells.

Autori: Probst S Romanova N Herbrechter R a ďalší

Zdroj: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2025 Dec; Vol. 1872 (8), pp. 120041. Date of Electronic Publication: 2025 Aug 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Kidney Tubules, Collecting*/metabolism , Kidney Tubules, Collecting*/cytology , Oxidative Stress* , Ion Channels*/metabolism , Ion Channels*/genetics , Catalase*/metabolism , Catalase*/genetics , Calcium*/metabolism , Kidney Medulla*/metabolism , Kidney Medulla*/cytology , Calcium Signaling*, Animals ; Mice ; Osmotic Pressure ; Cell Line ; Reactive Oxygen Species/metabolism

Mechanosensory Piezo2 regulated by gut microbiota participates in the development of visceral hypersensitivity and intestinal dysmotility.

Autori: Zheng H Chen Y Lu S a ďalší

Zdroj: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2497399. Date of Electronic Publication: 2025 Apr 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

Výrazy zo slovníka MeSH: Gastrointestinal Microbiome*/physiology , Irritable Bowel Syndrome*/microbiology , Irritable Bowel Syndrome*/physiopathology , Irritable Bowel Syndrome*/metabolism , Irritable Bowel Syndrome*/therapy , Ion Channels*/metabolism , Ion Channels*/genetics , Gastrointestinal Motility*, Animals ; Humans ; Mice ; Male ; Female ; Fecal Microbiota Transplantation ; Adult ; Middle Aged ; Colon/metabolism ; Mice, Inbred C57BL ; Feces/microbiology ; Fusobacterium/physiology ; Dysbiosis/microbiology ; Disease Models, Animal ; Ganglia, Spinal/metabolism ; Akkermansia

SCR Organism: Akkermansia muciniphila

Neutron reflectometry reveals conformational changes in a mechanosensitive protein induced by an antimicrobial peptide in tethered lipid bilayers.

Autori: Ayscough SE Skoda MWA Doutch J a ďalší

Zdroj: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Dec; Vol. 699 (Pt 1), pp. 138110. Date of Electronic Publication: 2025 Jun 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lipid Bilayers*/chemistry , Ion Channels*/chemistry , Ion Channels*/metabolism , Antimicrobial Peptides*/chemistry , Antimicrobial Peptides*/pharmacology , Escherichia coli Proteins*/chemistry , Escherichia coli Proteins*/metabolism , Antimicrobial Cationic Peptides*/chemistry, Protein Conformation ; Neutron Diffraction

Piezo1 Agonist Yoda1 Induces Rapid Relaxation in Cultured Airway Smooth Muscle Cells and Bronchodilation in Mouse Models.

Autori: Luo M Zhang X Guo J a ďalší

Zdroj: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2025 Dec; Vol. 73 (6), pp. 849-858.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myocytes, Smooth Muscle*/drug effects , Myocytes, Smooth Muscle*/metabolism , Ion Channels*/agonists , Ion Channels*/metabolism , Asthma*/drug therapy , Asthma*/metabolism , Asthma*/pathology , Asthma*/physiopathology , Bronchodilator Agents*/pharmacology , Muscle Relaxation*/drug effects , Quinazolines*/pharmacology, Animals ; Disease Models, Animal ; Mice ; Cells, Cultured ; Mice, Inbred BALB C ; Calcium Signaling/drug effects ; Pyrazines ; Thiadiazoles

The research progress into cellular mechanosensitive ion channels mediating cancer pain.

Autori: Liu C Li H Hang L

Zdroj: Channels (Austin, Tex.) [Channels (Austin)] 2025 Dec; Vol. 19 (1), pp. 2517109. Date of Electronic Publication: 2025 Jun 14.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6969 (Electronic) Linking ISSN: 19336950 NLM ISO Abbreviation: Channels (Austin) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mechanotransduction, Cellular* , Ion Channels*/metabolism , Cancer Pain*/metabolism , Cancer Pain*/drug therapy , Potassium Channels, Tandem Pore Domain*/metabolism , Neoplasms*/metabolism, Humans ; Animals

Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.

Autori: Liang P Wan YS Shan KZ a ďalší

Zdroj: American journal of hematology [Am J Hematol] 2025 Dec; Vol. 100 (12), pp. 2261-2275. Date of Electronic Publication: 2025 Oct 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/metabolism , Anemia, Sickle Cell*/drug therapy , Anemia, Sickle Cell*/blood , Anemia, Sickle Cell*/pathology , Anoctamins*/metabolism , Anoctamins*/genetics , Phospholipid Transfer Proteins*/metabolism , Phospholipid Transfer Proteins*/genetics , Ion Channels*/metabolism , Ion Channels*/antagonists & inhibitors , Ion Channels*/genetics, Humans ; Phosphatidylserines/metabolism ; Erythrocytes, Abnormal/metabolism ; Erythrocytes, Abnormal/pathology ; Calcium/metabolism ; Mechanotransduction, Cellular/drug effects ; Erythrocytes/metabolism

The critical role of ion channels in kidney disease: perspective from AKI and CKD.

Autori: Li CSZ Yu B Gao Q a ďalší

Zdroj: Renal failure [Ren Fail] 2025 Dec; Vol. 47 (1), pp. 2488139. Date of Electronic Publication: 2025 Apr 28.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

Výrazy zo slovníka MeSH: Acute Kidney Injury*/metabolism , Acute Kidney Injury*/physiopathology , Renal Insufficiency, Chronic*/metabolism , Renal Insufficiency, Chronic*/physiopathology , Ion Channels*/metabolism , Transient Receptor Potential Channels*/metabolism, Humans ; Oxidative Stress ; Animals ; Kidney/metabolism ; Kidney/pathology

A conserved Piezo-mRPL2/Jun axis controls reproduction via mitochondrial bioenergetics.

Autori: Luo J Lu Y Zhang Z a ďalší

Zdroj: Insect biochemistry and molecular biology [Insect Biochem Mol Biol] 2025 Dec; Vol. 185, pp. 104417. Date of Electronic Publication: 2025 Oct 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 9207282 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0240 (Electronic) Linking ISSN: 09651748 NLM ISO Abbreviation: Insect Biochem Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mitochondria*/metabolism , Ion Channels*/metabolism , Ion Channels*/genetics , Insect Proteins*/metabolism , Insect Proteins*/genetics , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/genetics , Ribosomal Proteins*/metabolism , Ribosomal Proteins*/genetics, Animals ; Male ; Energy Metabolism ; Reproduction ; Fertility ; Mice

Acid-Sensing PAC Channel Promotes Astrocyte Acidosis in Ischemic Stroke.

Autori: Liu Y Zhang Y Sun M a ďalší

Zdroj: Glia [Glia] 2025 Dec; Vol. 73 (12), pp. 2353-2368. Date of Electronic Publication: 2025 Jul 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Astrocytes*/metabolism , Astrocytes*/pathology , Ischemic Stroke*/metabolism , Ischemic Stroke*/pathology , Acidosis*/metabolism , Acidosis*/pathology , Acid Sensing Ion Channels*/metabolism , Acid Sensing Ion Channels*/genetics , Brain Ischemia*/metabolism , Brain Ischemia*/pathology, Animals ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Male ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/metabolism