Suchergebnisse - "Intercellular Junctions"

microRNA-184 distribution and consequences on glial septate junctions and the blood-brain barrier.

Autoren: Paluri S Auld VJ

Quelle: PloS one [PLoS One] 2025 Dec 04; Vol. 20 (12), pp. e0328862. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/genetics , MicroRNAs*/metabolism , Blood-Brain Barrier*/metabolism , Neuroglia*/metabolism , Drosophila melanogaster*/genetics , Drosophila melanogaster*/metabolism , Intercellular Junctions*/metabolism , Intercellular Junctions*/genetics, Animals ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism

Growth hormone modulates epithelial intercellular junctions structure and intestinal permeability in zebrafish.

Autoren: Meirelles MG Fénero CIM Nornberg BF et al.

Quelle: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology [Comp Biochem Physiol A Mol Integr Physiol] 2025 Dec; Vol. 310, pp. 111936. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9806096 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-4332 (Electronic) Linking ISSN: 10956433 NLM ISO Abbreviation: Comp Biochem Physiol A Mol Integr Physiol Subsets: MEDLINE

MeSH-Schlagworte: Zebrafish*/metabolism , Zebrafish*/genetics , Growth Hormone*/metabolism , Growth Hormone*/genetics , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/ultrastructure , Tight Junctions*/metabolism , Tight Junctions*/ultrastructure , Intercellular Junctions*/metabolism , Intercellular Junctions*/ultrastructure, Animals ; Permeability ; Animals, Genetically Modified ; Zebrafish Proteins/metabolism ; Zebrafish Proteins/genetics ; Intestinal Barrier Function

A Novel Compound Heterozygous Mutation in TEX14 Causes Human Non-Obstructive Azoospermia by Disrupting the Assembly of Intercellular Bridges.

Autoren: Li G Zhou S Li Y et al.

Quelle: Clinical genetics [Clin Genet] 2025 Dec; Vol. 108 (6), pp. 742-746. Date of Electronic Publication: 2025 Jun 10.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 0253664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0004 (Electronic) Linking ISSN: 00099163 NLM ISO Abbreviation: Clin Genet Subsets: MEDLINE

MeSH-Schlagworte: Azoospermia*/genetics , Azoospermia*/pathology , Mutation* , Cell Cycle Proteins*/genetics , Intercellular Junctions*/genetics , Intercellular Junctions*/pathology, Male ; Humans ; Spermatogenesis/genetics ; Heterozygote ; Testis/pathology ; Testis/metabolism ; Meiosis/genetics ; Adult

SCR Disease Name: Azoospermia, Nonobstructive

Coordinated regulation of Vangl2 trafficking by Kif13 and AP-1 underlies cell-cell junction remodeling in Eriocheir sinensis testis.

Autoren: Zhao Z Qi HY Wang JM et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 333 (Pt 1), pp. 148920. Date of Electronic Publication: 2025 Nov 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Kinesins*/metabolism , Kinesins*/genetics , Testis*/metabolism , Testis*/cytology , Intercellular Junctions*/metabolism , Nerve Tissue Proteins*/metabolism , Membrane Proteins*/metabolism , Transcription Factor AP-1*/metabolism, Male ; Animals ; Protein Transport ; Spermatogenesis ; Signal Transduction ; Cell Polarity

The kidney slit diaphragm resembles a fishnet.

Autoren: Birtasu AN Wieland K Ermel UH et al.

Quelle: Kidney international [Kidney Int] 2025 Dec; Vol. 108 (6), pp. 1045-1056. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE

MeSH-Schlagworte: Membrane Proteins*/chemistry , Membrane Proteins*/ultrastructure , Membrane Proteins*/metabolism , Kidney Glomerulus*/ultrastructure , Intercellular Junctions*/ultrastructure , Glomerular Filtration Barrier*/ultrastructure, Animals ; Mice, Inbred C57BL ; Mice ; Cryoelectron Microscopy ; Electron Microscope Tomography ; Podocytes/ultrastructure ; Molecular Dynamics Simulation

Epidermal stem cells control periderm injury repair via matrix-driven specialization of intercellular junctions.

Autoren: He HM Boraas LC Bell JM et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 10; Vol. 16 (1), pp. 8967. Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Extracellular Matrix*/metabolism , Stem Cells*/metabolism , Stem Cells*/cytology , Wound Healing*/physiology , Epidermis*/metabolism , Epidermal Cells*/metabolism , Intercellular Junctions*/metabolism, Animals ; Humans ; Laminin/metabolism ; Zebrafish ; Keratinocytes/metabolism ; Keratinocytes/cytology ; Desmosomes/metabolism ; Adherens Junctions/metabolism ; Collagen/metabolism ; Basement Membrane/metabolism ; Cell Differentiation ; Zebrafish Proteins/metabolism ; Zebrafish Proteins/genetics ; Desmoplakins/metabolism ; Desmoplakins/genetics

Impact of diabetes on cellular connections: Pathological insights and emerging therapeutic targets.

Autoren: Kanwal A Kanwar N Shetty MP et al.

Quelle: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2025 Aug; Vol. 19 (8), pp. 103300. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article; Systematic Review; Review

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101462250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0334 (Electronic) Linking ISSN: 18714021 NLM ISO Abbreviation: Diabetes Metab Syndr Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus*/pathology , Diabetes Mellitus*/metabolism , Intercellular Junctions*/pathology , Intercellular Junctions*/metabolism , Gap Junctions*/pathology , Gap Junctions*/metabolism, Humans ; Animals

The thrombin receptor PAR1 orchestrates changes in lymphatic endothelial cell junction morphology to augment lymphatic drainage during lung injury.

Autoren: Chou C Paredes CC Summers B et al.

Quelle: Nature cardiovascular research [Nat Cardiovasc Res] 2025 Aug; Vol. 4 (8), pp. 964-975. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Nature Country of Publication: England NLM ID: 9918284280206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-0590 (Electronic) Linking ISSN: 27310590 NLM ISO Abbreviation: Nat Cardiovasc Res Subsets: MEDLINE

MeSH-Schlagworte: Receptor, PAR-1*/metabolism , Receptor, PAR-1*/genetics , Receptor, PAR-1*/deficiency , Lymphatic Vessels*/metabolism , Lymphatic Vessels*/pathology , Lymphatic Vessels*/physiopathology , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Intercellular Junctions*/metabolism , Intercellular Junctions*/pathology , Lung Injury*/metabolism , Lung Injury*/pathology , Lung*/metabolism , Lung*/pathology, Animals ; Disease Models, Animal ; Mice, Inbred C57BL ; Signal Transduction ; Male ; Mice, Knockout ; Humans ; Mice ; Cells, Cultured

The role of cell junctions in atherosclerosis: implications for inflammation, endothelial dysfunction, and plaque stability.

Autoren: Dabravolski SA Kashtalap VV Rozhkova UV et al.

Quelle: Journal of physiology and biochemistry [J Physiol Biochem] 2025 Aug; Vol. 81 (3), pp. 573-587. Date of Electronic Publication: 2025 Jul 04.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Servicio de Publicaciones de la Universidad De Navarra (departamentos de fisiología y nutrición y de bioquimica) Country of Publication: Spain NLM ID: 9812509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-8755 (Electronic) Linking ISSN: 11387548 NLM ISO Abbreviation: J Physiol Biochem Subsets: MEDLINE

MeSH-Schlagworte: Atherosclerosis*/pathology , Atherosclerosis*/metabolism , Plaque, Atherosclerotic*/metabolism , Plaque, Atherosclerotic*/pathology , Inflammation*/metabolism , Inflammation*/pathology , Endothelium, Vascular*/metabolism , Endothelium, Vascular*/pathology , Endothelium, Vascular*/physiopathology , Intercellular Junctions*/metabolism , Intercellular Junctions*/pathology , Endothelial Cells*/metabolism , Endothelial Cells*/pathology, Humans ; Animals ; Tight Junctions/metabolism ; Tight Junctions/pathology ; Signal Transduction ; Adherens Junctions/metabolism ; Adherens Junctions/pathology ; Gap Junctions/metabolism ; Gap Junctions/pathology

The SARS-CoV-2 envelope PDZ binding motif acts as a virulence factor disrupting host's epithelial cell-cell junctions.

Autoren: Alvarez F de Melo GD Larrous F et al.

Quelle: Cellular & molecular biology letters [Cell Mol Biol Lett] 2025 Jul 11; Vol. 30 (1), pp. 80. Date of Electronic Publication: 2025 Jul 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE

MeSH-Schlagworte: SARS-CoV-2*/pathogenicity , SARS-CoV-2*/genetics , SARS-CoV-2*/metabolism , COVID-19*/virology , COVID-19*/pathology , COVID-19*/metabolism , Epithelial Cells*/virology , Epithelial Cells*/metabolism , Epithelial Cells*/pathology , Virulence Factors*/metabolism , Virulence Factors*/genetics , Intercellular Junctions*/metabolism , Intercellular Junctions*/virology , Intercellular Junctions*/pathology , Coronavirus Envelope Proteins*/metabolism , Coronavirus Envelope Proteins*/genetics , Coronavirus Envelope Proteins*/chemistry, Animals ; PDZ Domains ; Humans ; Cricetinae ; Virus Replication ; Virulence ; Zonula Occludens-1 Protein/metabolism ; Chlorocebus aethiops ; Vero Cells

Supracellular actomyosin assemblies: master coordinators of development.

Autoren: Röper K; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB3 3DY, UK.; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

Quelle: Development (Cambridge, England) [Development] 2025 Aug 15; Vol. 152 (16). Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH-Schlagworte: Actomyosin*/physiology , Intercellular Junctions*/physiology , Morphogenesis*, Animals

Piezo1 balances membrane and cortex tension to stabilize intercellular junctions and maintain the epithelial barrier.

Autoren: Javed A Stubb A Villeneuve C et al.

Quelle: Journal of cell science [J Cell Sci] 2025 Aug 15; Vol. 138 (16). Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

MeSH-Schlagworte: Ion Channels*/metabolism , Ion Channels*/genetics , Intercellular Junctions*/metabolism , Tight Junctions*/metabolism , Cell Membrane*/metabolism , Epithelial Cells*/metabolism, Animals ; Mice ; Epidermis/metabolism ; Cell Adhesion ; Adherens Junctions/metabolism ; Keratinocytes/metabolism ; Mice, Knockout

Myocardin-related transcription factor regulates actomyosin contractility and apical junction remodeling during vertebrate neural tube closure.

Autoren: Itoh K Ossipova O Sokol SY

Quelle: Development (Cambridge, England) [Development] 2025 Aug 15; Vol. 152 (16). Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH-Schlagworte: Actomyosin*/metabolism , Neural Tube*/embryology , Neural Tube*/metabolism , Xenopus Proteins*/metabolism , Xenopus Proteins*/genetics , Xenopus laevis*/embryology , Xenopus laevis*/metabolism , Intercellular Junctions*/metabolism , Trans-Activators*/metabolism , Trans-Activators*/genetics, Animals ; Actins/metabolism ; Gene Expression Regulation, Developmental ; Ectoderm/metabolism ; Ectoderm/embryology ; Myosin Type II/metabolism ; Neurulation/physiology ; Embryo, Nonmammalian/metabolism

IL-19 Is a Novel Lymphangiocrine Factor Inducing Lymphangiogenesis and Lymphatic Junctional Regulation.

Autoren: Peluzzo AM St Paul A Corbett CB et al.

Quelle: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2025 Jul; Vol. 45 (7), pp. 1244-1265. Date of Electronic Publication: 2025 May 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

MeSH-Schlagworte: Lymphangiogenesis*/drug effects , Lymphatic Vessels*/metabolism , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects , Interleukins*/genetics , Interleukins*/metabolism , Intercellular Junctions*/metabolism, Animals ; Humans ; Mice, Knockout ; Cells, Cultured ; Cadherins/metabolism ; Vascular Endothelial Growth Factor C/metabolism ; Vascular Endothelial Growth Factor C/pharmacology ; Signal Transduction ; Mice ; Cell Movement ; Mice, Inbred C57BL ; Antigens, CD

HIF-1α-Mediated Disruption of Cellular Junctions: The Impact of Hypoxia on the Tumor Microenvironment and Invasion.

Autoren: Springer M Burakgazi ZA Domukhovska A et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 May 26; Vol. 26 (11). Date of Electronic Publication: 2025 May 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Tumor Microenvironment* , Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism , Neoplasms*/pathology , Neoplasms*/metabolism , Intercellular Junctions*/metabolism , Intercellular Junctions*/pathology , Hypoxia*/metabolism, Humans ; Animals ; Neoplasm Invasiveness ; Epithelial-Mesenchymal Transition ; Signal Transduction

Assessment of Corneal Endothelial Barrier Function Based on "Y-Junctions": A Finite Element Analysis.

Autoren: Li D Duan H Wang X et al.

Quelle: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 May 01; Vol. 66 (5), pp. 33.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH-Schlagworte: Endothelium, Corneal*/ultrastructure , Endothelium, Corneal*/metabolism , Endothelium, Corneal*/physiology , Finite Element Analysis* , Intercellular Junctions*/ultrastructure , Intercellular Junctions*/physiology , Corneal Diseases*/physiopathology, Animals ; Rabbits ; Humans ; Microscopy, Electron, Scanning ; Mice ; Intraocular Pressure/physiology ; Disease Models, Animal ; Male ; Mice, Inbred C57BL

Junctional force patterning drives both positional order and planar polarity in the auditory epithelia.

Autoren: Prakash A Weninger J Singh N et al.

Quelle: Nature communications [Nat Commun] 2025 Apr 26; Vol. 16 (1), pp. 3927. Date of Electronic Publication: 2025 Apr 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Cell Polarity*/physiology , Hair Cells, Auditory*/metabolism , Hair Cells, Auditory*/physiology , Hair Cells, Auditory*/cytology , Cochlea*/cytology , Cochlea*/metabolism , Intercellular Junctions*/metabolism , Intercellular Junctions*/physiology, Animals ; Myosin Type II/metabolism ; Mice ; Epithelium/metabolism ; Myosin Light Chains/metabolism

Conserved mechanical hallmark guides four-way junction avoidance during plant cytokinesis.

Autoren: Gascon E Goldy C Lebecq A et al.

Quelle: Current biology : CB [Curr Biol] 2025 Jun 23; Vol. 35 (12), pp. 2789-2801.e6. Date of Electronic Publication: 2025 May 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE

MeSH-Schlagworte: Arabidopsis*/genetics , Arabidopsis*/physiology , Arabidopsis*/cytology , Cytokinesis*/physiology , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Intercellular Junctions*/physiology, Microtubules/metabolism ; Plant Roots/physiology ; Plant Roots/cytology

Weakened Airway Epithelial Junctions and Enhanced Neutrophil Elastase Release Contribute to Age-Dependent Bacteremia Risk Following Pneumococcal Pneumonia.

Autoren: Xu S Zhu T Mou H et al.

Quelle: Aging cell [Aging Cell] 2025 May; Vol. 24 (5), pp. e14474. Date of Electronic Publication: 2025 Jan 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

MeSH-Schlagworte: Pneumonia, Pneumococcal*/complications , Pneumonia, Pneumococcal*/pathology , Pneumonia, Pneumococcal*/microbiology , Leukocyte Elastase*/metabolism , Bacteremia*/pathology , Bacteremia*/microbiology , Aging* , Intercellular Junctions*/metabolism , Respiratory Mucosa*/pathology , Respiratory Mucosa*/metabolism, Animals ; Mice ; Humans ; Streptococcus pneumoniae/pathogenicity ; Streptolysins/metabolism ; Mice, Inbred C57BL ; Cadherins/metabolism ; Neutrophils ; Epithelial Cells/metabolism ; Bacterial Proteins

Disruption of P2Y2 Signaling Promotes Breast Tumor Cell Dissemination by Reducing ATP-Dependent Calcium Elevation and Actin Localization to Cell Junctions.

Autoren: Mull ML Pratt SJP Thompson KN et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 May 01; Vol. 26 (9). Date of Electronic Publication: 2025 May 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Purinergic P2Y2*/metabolism , Receptors, Purinergic P2Y2*/genetics , Adenosine Triphosphate*/metabolism , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Calcium*/metabolism , Actins*/metabolism , Intercellular Junctions*/metabolism, Humans ; Female ; Signal Transduction ; Cell Line, Tumor ; Tumor Microenvironment ; Epithelial Cells/metabolism ; Calcium Signaling ; Cell Movement