Výsledky vyhledávání - "Inhibitory Postsynaptic Potentials - drug effects"

The Selective 5HT2A Receptor Agonist, 25CN‐NBOH Exerts Excitatory and Inhibitory Cellular Actions on Mouse Medial Prefrontal Cortical Neurons

Autoři: Yang Wang Jesper L. Kristensen Kristi A. Kohlmeier

Zdroj: Synapse
Wang, Y, Kristensen, J L & Kohlmeier, K A 2025, ' The Selective 5HT 2A Receptor Agonist, 25CN-NBOH Exerts Excitatory and Inhibitory Cellular Actions on Mouse Medial Prefrontal Cortical Neurons ', Synapse (New York, N.Y.), vol. 79, no. 2, e70014 . https://doi.org/10.1002/syn.70014

Témata: Male, Neurons, Receptor, Serotonin, 5-HT2A/metabolism, Patch-Clamp Techniques, Pyramidal Cells, Prefrontal Cortex, Excitatory Postsynaptic Potentials, Neurons/drug effects, Mice, Inbred C57BL, Mice, Bridged Bicyclo Compounds, Methylamines, Inhibitory Postsynaptic Potentials, Serotonin 5-HT2 Receptor Agonists/pharmacology, Inhibitory Postsynaptic Potentials/drug effects, Hallucinogens/pharmacology, Hallucinogens, Animals, Prefrontal Cortex/drug effects, Receptor, Serotonin, 5-HT2A, Pyramidal Cells/drug effects, Excitatory Postsynaptic Potentials/drug effects, Serotonin 5-HT2 Receptor Agonists, Research Article

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40128102
https://curis.ku.dk/ws/files/445675314/Synapse_-_2025_-_Wang_-_The_Selective_5HT2A_Receptor_Agonist_25CN_NBOH_Exerts_Excitatory_and_Inhibitory_Cellular_Actions.pdf

SHANK3 controls maturation of social reward circuits in the VTA.

Autoři: Bariselli, S. Tzanoulinou, S. Glangetas, C. a další

Témata: Animals, Autism Spectrum Disorder/metabolism, Behavior, Animal/physiology, Dopamine/metabolism, Dopaminergic Neurons/metabolism, GABAergic Neurons/drug effects, Hippocampus/metabolism, Inhibitory Postsynaptic Potentials/drug effects, Mice, Inbred C57BL, Transgenic, Nerve Tissue Proteins/metabolism, Patch-Clamp Techniques/methods, Reward, Synapses/metabolism, Synaptic Transmission/physiology, Ventral Tegmental Area/metabolism

Popis souboru: application/pdf

Relation: Nature Neuroscience; https://iris.unil.ch/handle/iris/82303; serval:BIB_07C0F4A52247; 000378759600011

Dostupnost: https://iris.unil.ch/handle/iris/82303
https://doi.org/10.1038/nn.4319

Phasic, nonsynaptic GABA-A receptor-mediated inhibition entrains thalamocortical oscillations.

Autoři: Rovó, Z. Mátyás, F. Barthó, P. a další

Témata: Animals, Cerebral Cortex/physiology, Dependovirus/genetics, Excitatory Amino Acid Antagonists/pharmacology, GABA Antagonists/pharmacology, Inhibitory Postsynaptic Potentials/drug effects, Inhibitory Postsynaptic Potentials/genetics, Mice, Inbred C57BL, Transgenic, Neural Inhibition/physiology, Neurons/physiology, Pyridazines/pharmacology, Receptors, GABA-A/genetics, GABA-A/metabolism, Synapses/drug effects, Synapses/genetics, Thalamus/physiology, Vesicular Glutamate Transport Protein 2/metabolism, gamma-Aminobutyric Acid/metabolism

Popis souboru: application/pdf

Relation: The Journal of Neuroscience; https://iris.unil.ch/handle/iris/42291; serval:BIB_32020D0588AB; 000336895200011

Dostupnost: https://iris.unil.ch/handle/iris/42291
https://doi.org/10.1523/JNEUROSCI.4386-13.2014

Prokineticin 2 regulates the electrical activity of rat suprachiasmatic nuclei neurons.

Autoři: Ren, Ping Zhang, Huiping Qiu, Fang a další

Zdroj: PloS one. 6(6)

Témata: Animals, Electric Conductivity, Electrophysiological Processes: drug effects, Gastrointestinal Hormones: metabolism, Inhibitory Postsynaptic Potentials: drug effects, Male, Neurons: cytology, drug effects, metabolism, Neuropeptides: metabolism, Protein Kinase C: antagonists & inhibitors, metabolism, Protein Kinase Inhibitors: pharmacology, Rats, Rats, Sprague-Dawley, Receptors, GABA-A: metabolism, Suprachiasmatic Nucleus: cytology, drug effects, metabolism, physiology, gamma-Aminobutyric Acid: pharmacology

Popis souboru: application/pdf

Přístupová URL adresa: https://escholarship.org/uc/item/0j53r5gx
https://escholarship.org/content/qt0j53r5gx/qt0j53r5gx.pdf

Inflammatory Pain Promotes Increased Opioid Self-Administration: Role of Dysregulated Ventral Tegmental Area μ Opioid Receptors

Autoři: Lucia Hipólito Adrianne Wilson-Poe Yolanda Campos-Jurado a další

Zdroj: The Journal of Neuroscience. 35:12217-12231

Témata: Ventral Tegmental Area - drug effects, Male, Glycine Agents - pharmacology, Receptors, Opioid, mu, Action Potentials, Pain - pathology, Ala-MePhe-Gly- - administration & dosage, Hyperalgesia - drug therapy, Rats, Sprague-Dawley, 0302 clinical medicine, Enkephalin, Receptors, Heroin - administration & dosage, Action Potentials - drug effects, Neurons, Analgesics, Inhibitory Postsynaptic Potentials - drug effects, Quinoxalines - pharmacology, Glycine Agents, 3. Good health, Analgesics, Opioid, Inflammation - complications, Hyperalgesia, mu - metabolism, Excitatory Amino Acid Antagonists - pharmacology, Inflammation - chemically induced, Pain - psychology, Pain Threshold, Neurons - drug effects, Pain, Opioid, 03 medical and health sciences, Ventral Tegmental Area - pathology, Strychnine - pharmacology, Quinoxalines, Animals, Pain Threshold - drug effects, Inflammation, Animal, Enkephalin, Ala(2)-MePhe(4)-Gly(5), Pain - drug therapy, Rats, Heroin, Disease Models, Animal, Inhibitory Postsynaptic Potentials, Operant - drug effects, Ventral Tegmental Area - metabolism, Disease Models, Conditioning, Operant, Sprague-Dawley, Sucrose - administration & dosage, Excitatory Amino Acid Antagonists, Conditioning, Opioid - administration & dosage

Popis souboru: application/pdf

Přístupová URL adresa: https://www.jneurosci.org/content/jneuro/35/35/12217.full.pdf
https://pubmed.ncbi.nlm.nih.gov/26338332
https://www.jneurosci.org/content/jneuro/35/35/12217.full.pdf
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=5340&context=open_access_pubs
https://www.jneurosci.org/content/35/35/12217.abstract
https://www.ncbi.nlm.nih.gov/pubmed/26338332
https://digitalcommons.wustl.edu/open_access_pubs/4336/
http://europepmc.org/articles/PMC4556787

Control of Inhibition by the Direct Action of Cannabinoids on GABAAReceptors

Autoři: Golovko, T Min, R Lozovaya, N a další

Zdroj: Golovko, T, Min, R, Lozovaya, N, Falconer, C, Yatsenko, N, Tsintsadze, T, Tsintsadze, V, Ledent, C, Harvey, R J, Belelli, D, Lambert, J J, Rozov, A & Burnashev, N 2015, 'Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors', Cerebral Cortex, vol. 25, no. 9, pp. 2440-55. https://doi.org/10.1093/cercor/bhu045

Témata: 0301 basic medicine, Cb receptors, Patch-Clamp Techniques, Wistar, Action Potentials, Neocortex, Inhibitory synaptic transmission, Action Potentials/drug effects, Inbred C57BL, Hippocampus, Synaptic Transmission, 7. Clean energy, Transgenic, CB1/genetics, Rats, Sprague-Dawley, Mice, FoR 1701 (Psychology), Receptor, Cannabinoid, CB1, DSI, Cannabinoids/metabolism, Receptors, neocortex, 0303 health sciences, fast-spiking interneurons, Sciences bio-médicales et agricoles, name=Cognitive Neuroscience, 3. Good health, Hippocampus/cytology, Inhibitory Postsynaptic Potentials/drug effects, FoR 1109 (Neurosciences), GABA/metabolism, Receptor, GABA Agents/pharmacology, GABA Agents, Synaptic Transmission/drug effects, Mice, Transgenic, In Vitro Techniques, Transfection, Neural Inhibition/drug effects, FoR 1702 (Cognitive Sciences), 03 medical and health sciences, Cb1 receptors, SDG 3 - Good Health and Well-being, Receptors, GABA, Animals, Humans, endocannabinoids, name=General Medicine, Rats, Wistar, Cannabinoid, Cannabinoids, Neural Inhibition, Newborn, Rats, Fast-spiking interneurons, Mice, Inbred C57BL, inhibitory synaptic transmission, Animals, Newborn, Inhibitory Postsynaptic Potentials, Sprague-Dawley, CB1 receptors, name=Cellular and Molecular Neuroscience, Endocannabinoids

Popis souboru: 1 full-text file(s): application/pdf

Přístupová URL adresa: https://academic.oup.com/cercor/article-pdf/25/9/2440/14108255/bhu045.pdf
https://pubmed.ncbi.nlm.nih.gov/24646614
https://www.narcis.nl/publication/RecordID/oai%3Apure.knaw.nl%3Apublications%2F1e0470f6-26c8-4c13-adf4-5449f414eb51
https://academic.oup.com/cercor/article/25/9/2440/2926056
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/237117/Details
http://discovery.ucl.ac.uk/1432018/
https://www.ncbi.nlm.nih.gov/pubmed/24646614
https://europepmc.org/abstract/MED/24646614
https://research.vumc.nl/en/publications/87fc0b3e-ceed-45c1-b4db-88a6d694fdfe

Contribution of Adenylyl Cyclase Modulation of Pre- and Postsynaptic GABA Neurotransmission to Morphine Antinociception and Tolerance

Autoři: Bobeck, Erin N Chen, QiLiang Morgan, Michael M a další

Přispěvatelé: Bobeck, Erin N Chen, QiLiang Morgan, Michael M a další

Zdroj: Neuropsychopharmacology. 39:2142-2152

Témata: Male, Nociception, 0301 basic medicine, Synaptic Transmission, Rats, Sprague-Dawley, Morphine - pharmacology, Receptors, Enzyme Inhibitors, Bicuculline - pharmacology, Analgesics, 0303 health sciences, Opioid - pharmacology, Inhibitory Postsynaptic Potentials - physiology, Morphine, Inhibitory Postsynaptic Potentials - drug effects, Miniature Postsynaptic Potentials, Colforsin - pharmacology, 1. No poverty, Drug Tolerance, Analgesics, Opioid, Nociception - drug effects, Synaptic Transmission - physiology, Enzyme Inhibitors - pharmacology, Adenylyl Cyclase, Miniature Postsynaptic Potentials - physiology, Adenylyl Cyclases, Presynaptic Terminals, Enzyme Activators, Nociception - physiology, Synaptic Transmission - drug effects, Adenine - analogs & derivatives, gamma-Aminobutyric Acid - metabolism, Bicuculline, 03 medical and health sciences, Enzyme Activators - pharmacology, GABA-A Receptor Antagonists - pharmacology, Animals, GABA-A Receptor Antagonists, Biology, Adenylyl Cyclases - metabolism, GABA-A - metabolism, Adenine, Colforsin, Presynaptic Terminals - drug effects, Adenine - pharmacology, Presynaptic Terminals - enzymology, Receptors, GABA-A, Rats, Inhibitory Postsynaptic Potentials, Adenylyl Cyclase Inhibitors, Sprague-Dawley, Miniature Postsynaptic Potentials - drug effects, GABA Neurotransmission

Přístupová URL adresa: https://www.nature.com/articles/npp201462.pdf
https://pubmed.ncbi.nlm.nih.gov/24622471
https://pubmed.ncbi.nlm.nih.gov/24622471/
https://www.ncbi.nlm.nih.gov/pubmed/24622471
https://digitalcommons.usu.edu/biology_facpub/1701/
https://ohsu.pure.elsevier.com/en/publications/contribution-of-adenylyl-cyclase-modulation-of-pre-and-postsynapt-2
http://europepmc.org/articles/PMC4104331
http://www.readcube.com/articles/10.1038/npp.2014.62

Methamphetamine-Evoked Depression of GABAB Receptor Signaling in GABA Neurons of the VTA

Autoři: Michaelanne B. Munoz Stephen J. Moss Claire L. Padgett a další

Zdroj: Neuron, Vol. 73, No 5 (2012) pp. 978-89
Neuron

Témata: Male, 0301 basic medicine, Baclofen, Dopamine, Dopamine Agents, Down-Regulation/drug effects, Action Potentials, GABA-B Receptor Agonists/pharmacology, Receptors, GABA-A/metabolism/ultrastructure, Mice, Drug Interactions, Phosphorylation, Dopamine/pharmacology, 0303 health sciences, Dopamine Agents/pharmacology, Action Potentials/drug effects/genetics, Glutamate Decarboxylase, Microscopy, Immunoelectron/methods, Bacterial Proteins/genetics/metabolism, Female, Organophosphorus Compounds/pharmacology, 616.8, Neuroscience(all), Rhodopsin/genetics/metabolism, Green Fluorescent Proteins, Transcription Factors/genetics, Down-Regulation, Mice, Transgenic, In Vitro Techniques, Baclofen/pharmacology, Glutamate Decarboxylase/genetics, Gamma-Aminobutyric Acid/metabolism/pharmacology, 03 medical and health sciences, Bacterial Proteins, Channelrhodopsins, Green Fluorescent Proteins/genetics/metabolism, G Protein-Coupled Inwardly-Rectifying Potassium Channels/metabolism/ultrastructure, Neurons/drug effects/metabolism/ultrastructure, Animals, Luminescent Proteins/genetics/metabolism, Homeodomain Proteins, Ventral Tegmental Area/cytology/drug effects, ddc:616.8, Mice, Inbred C57BL, Luminescent Proteins, Animals, Newborn, G Protein-Coupled Inwardly-Rectifying Potassium Channels, Inhibitory Postsynaptic Potentials, GABA-B Receptor Agonists, Inhibitory Postsynaptic Potentials/drug effects/genetics, Methamphetamine/pharmacology, Central Nervous System Stimulants/pharmacology, Central Nervous System Stimulants, Homeodomain Proteins/genetics

Popis souboru: application/pdf

Přístupová URL adresa: http://www.cell.com/article/S0896627312000815/pdf
https://pubmed.ncbi.nlm.nih.gov/22405207
https://archive-ouverte.unige.ch/unige:26960
https://www.sciencedirect.com/science/article/pii/S0896627312000815
https://www.cell.com/neuron/abstract/S0896-6273(12)00081-5
http://www.srfcdn.ch/radio/modules/data/attachments/2014/Schlaefli_Lalive_article.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560416/figure/F6/
http://europepmc.org/articles/PMC3560416
https://archive-ouverte.unige.ch/unige:26960

Differential Modulation of Excitatory and Inhibitory Striatal Synaptic Transmission by Histamine

Autoři: Ellender, Tommas J Huerta-Ocampo, Icnelia Deisseroth, Karl a další

Zdroj: Journal of Neuroscience; Vol 31
Ellender, T J, Huerta-Ocampo, I, Deisseroth, K, Capogna, M & Bolam, J P 2011, 'Differential modulation of excitatory and inhibitory striatal synaptic transmission by histamine', The Journal of neuroscience, vol. 31, no. 43, pp. 15340-51. https://doi.org/10.1523/JNEUROSCI.3144-11.2011

Témata: Male, Tyrosine 3-Monooxygenase/metabolism, Piperidines/pharmacology, GABA Agents/pharmacology, Mutation/genetics, Patch-Clamp Techniques/methods, GABA Agents, Synaptic Transmission/drug effects, Green Fluorescent Proteins, Histamine Antagonists, Histamine Agonists/metabolism, Mice, Transgenic, Calcium-Calmodulin-Dependent Protein Kinase Type 2/genetics, In Vitro Techniques, Receptors, Dopamine D2/genetics, Neural Inhibition/drug effects, Hippocampus, Green Fluorescent Proteins/genetics, Vesicular Glutamate Transport Protein 1/metabolism, Histamine/metabolism, Histamine Agonists, Mice, 03 medical and health sciences, Excitatory Amino Acid Agents/pharmacology, 0302 clinical medicine, Neural Pathways/physiology, Channelrhodopsins, Vesicular Inhibitory Amino Acid Transport Proteins/metabolism, Histamine Antagonists/pharmacology, Animals, Parvalbumins/metabolism, Receptors, Dopamine D1/genetics, Excitatory Amino Acid Agents, Hippocampus/physiology, Excitatory Postsynaptic Potentials/drug effects, Corpus Striatum/cytology, Feedback, Physiological, Feedback, Physiological/drug effects, Excitatory Postsynaptic Potentials, Transfection/methods, Neurons/drug effects, Corpus Striatum, Electric Stimulation, Inhibitory Postsynaptic Potentials, Inhibitory Postsynaptic Potentials/drug effects, Female, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Thalamus/physiology, Histamine

Přístupová URL adresa: https://www.jneurosci.org/content/jneuro/31/43/15340.full.pdf
https://pubmed.ncbi.nlm.nih.gov/22031880
https://www.jneurosci.org/content/31/43/15340
https://www.neuroscience.ox.ac.uk/publications/329205
https://europepmc.org/article/MED/22031880
https://www.pharm.ox.ac.uk/publications/329205
http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.3144-11.2011
http://www.jneurosci.org/content/31/43/15340.full

Tolerance to the Antinociceptive Effect of Morphine in the Absence of Short-Term Presynaptic Desensitization in Rat Periaqueductal Gray Neurons

Autoři: Fyfe, Leon W Cleary, Daniel R Macey, Tara A a další

Zdroj: The Journal of Pharmacology and Experimental Therapeutics. 335:674-680

Témata: mu - antagonists & inhibitors, Male, 0301 basic medicine, Neurons - drug effects, Patch-Clamp Techniques, Enkephalin, Methionine, Receptors, Opioid, mu, Opioid, Rats, Sprague-Dawley, Drug Tolerance - physiology, 03 medical and health sciences, Morphine - pharmacology, Enkephalin, Naltrexone - analogs & derivatives, Electrophysiological Phenomena - physiology, Receptors, Signal Transduction - drug effects, Reaction Time, Morphine - administration & dosage, Animals, Periaqueductal Gray, Analgesics - administration & dosage, Pain Measurement, Electrophysiological Phenomena - drug effects, Neurons, Analgesics, 0303 health sciences, Methionine - pharmacology, Inhibitory Postsynaptic Potentials - physiology, Morphine, Inhibitory Postsynaptic Potentials - drug effects, Naltrexone - pharmacology, Drug Tolerance, Enkephalin, Ala(2)-MePhe(4)-Gly(5), Naltrexone, Reaction Time - drug effects, Electrophysiological Phenomena, Rats, mu - agonists, Inhibitory Postsynaptic Potentials, Periaqueductal Gray - drug effects, Periaqueductal Gray - physiology, Ala-MePhe-Gly- - pharmacology, Analgesics - pharmacology, Sprague-Dawley, Neurons - physiology, Signal Transduction

Přístupová URL adresa: https://europepmc.org/articles/pmc2993552?pdf=render
https://pubmed.ncbi.nlm.nih.gov/20739455
https://jpet.aspetjournals.org/content/jpet/early/2010/08/25/jpet.110.172643.full.pdf
https://www.ncbi.nlm.nih.gov/pubmed/20739455
https://ohsu.pure.elsevier.com/en/publications/tolerance-to-the-antinociceptive-effect-of-morphine-in-the-absenc-2
https://jpet.aspetjournals.org/content/335/3/674
http://europepmc.org/articles/PMC2993552/
https://jpet.aspetjournals.org/content/335/3/674.full.pdf

Diacylglycerol Lipase Is Not Involved in Depolarization-Induced Suppression of Inhibition at Unitary Inhibitory Connections in Mouse Hippocampus

Autoři: Min R TestaSilva G Heistek TS a další

Zdroj: 30 (2010): 2710–2715.
info:cnr-pdr/source/autori:Min R, Testa-Silva G, Heistek TS, Canto CB, Lodder JC, Bisogno T, Di Marzo V, Brussaard AB, Burnashev N, Mansvelder HD./titolo:Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus./doi:/rivista:/anno:2010/pagina_da:2710/pagina_a:2715/intervallo_pagine:2710–2715/volume:30
Min, R, Testa-Silva, G, Heistek, T S, Canto, C B, Lodder, J C, Bisogno, T, Di Marzo, V, Brussaard, A B, Burnashev, N & Mansvelder, H D 2010, 'Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus', Journal of Neuroscience, vol. 30, no. 7, pp. 2710-5. https://doi.org/10.1523/JNEUROSCI.BC-3622-09.2010

Témata: 0301 basic medicine, Benzoxazines/pharmacology, Knockout, Morpholines, Green Fluorescent Proteins, Neocortex/cytology, Valine/analogs & derivatives, Neocortex, In Vitro Techniques, Naphthalenes, Inbred C57BL, Neural Inhibition/drug effects, Hippocampus, Green Fluorescent Proteins/genetics, GABA Antagonists, Mice, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Animals, Enzyme Inhibitors, Electric Stimulation/methods, Cannabinoid, Enzyme Inhibitors/pharmacology, Mice, Knockout, Lysine/analogs & derivatives, 0303 health sciences, Cyclohexanones, Lysine, Pyridazines/pharmacology, Newborn, Neurons/drug effects, Electric Stimulation, Quinoxalines/pharmacology, Benzoxazines, Excitatory Amino Acid Antagonists/pharmacology, Mice, Inbred C57BL, Lipoprotein Lipase, Cyclohexanones/pharmacology, GABA Antagonists/pharmacology, Animals, Newborn, Inhibitory Postsynaptic Potentials, Hippocampus/cytology, Inhibitory Postsynaptic Potentials/drug effects, CB1/agonists, Morpholines/pharmacology, Lipoprotein Lipase/antagonists & inhibitors, Excitatory Amino Acid Antagonists, Naphthalenes/pharmacology, Receptor

Přístupová URL adresa: http://www.jneurosci.org/content/jneuro/30/7/2710.full.pdf
https://pubmed.ncbi.nlm.nih.gov/20164355
http://www.cnr.it/prodotto/i/16130
https://publications.cnr.it/doc/16130
https://research.vu.nl/en/publications/340d7f51-3217-44a7-8ced-00745e174337
https://hdl.handle.net/1871/21044
https://doi.org/10.1523/JNEUROSCI.BC-3622-09.2010
https://cris.maastrichtuniversity.nl/en/publications/74f26f18-718b-4d75-bf8d-e6835313fdec
https://doi.org/10.1523/JNEUROSCI.BC-3622-09.2010
https://www.jneurosci.org/content/30/7/2710
https://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.BC-3622-09.2010
https://cris.maastrichtuniversity.nl/en/publications/diacylglycerol-lipase-is-not-involved-in-depolarization-induced-s
https://europepmc.org/abstract/MED/20164355
https://research.vu.nl/ws/files/2729889/248292.pdf
https://www.ncbi.nlm.nih.gov/pubmed/20164355
https://research.vumc.nl/en/publications/602c7275-0544-4adc-bb9d-c6da07a5cb26
https://hdl.handle.net/20.500.14243/162129
https://pure.amsterdamumc.nl/en/publications/c79d3a0a-c999-4641-a920-c5404566bcb5
https://doi.org/10.1523/JNEUROSCI.BC-3622-09.2010

Neural bases for addictive properties of benzodiazepines

Autoři: Jean-Marc Fritschy Christian Lüscher Gwenaël Labouèbe a další

Přispěvatelé: Jean-Marc Fritschy Christian Lüscher Gwenaël Labouèbe a další

Zdroj: Nature
Nature, Vol. 463, No 7282 (2010) pp. 769-774

Témata: Gamma-Aminobutyric Acid/metabolism, Dopamine, Midazolam, 10050 Institute of Pharmacology and Toxicology, Action Potentials, Administration, Oral, Glutamic Acid, 610 Medicine & health, In Vitro Techniques, Action Potentials/drug effects, Receptors, AMPA/metabolism, Models, Biological, Article, Substrate Specificity, Morphine/pharmacology, Benzodiazepines, Mice, SX00 SystemsX.ch, Interneurons/drug effects/metabolism, Interneurons, Animals, Receptors, AMPA, Inhibitory Postsynaptic Potentials/drug effects/physiology, Neurons, 1000 Multidisciplinary, Neuronal Plasticity, Morphine, Electric Conductivity, Neuronal Plasticity/drug effects, Behavior, Addictive/ chemically induced/pathology/ physiopathology, Benzodiazepines/administration & dosage/ adverse effects/ pharmacology, Ventral Tegmental Area/cytology/drug effects/metabolism, ddc:616.8, Midazolam/administration & dosage/adverse effects/pharmacology, 3. Good health, Dopamine/metabolism, Behavior, Addictive, Mice, Inbred C57BL, Receptors, GABA-A/deficiency/genetics/metabolism, Inhibitory Postsynaptic Potentials, Glutamic Acid/metabolism, Organ Specificity, 570 Life sciences, biology, Neurons/ drug effects/metabolism, SX11 Neurochoice

Popis souboru: tan_nature_2010_769.pdf - application/pdf

Přístupová URL adresa: https://europepmc.org/articles/pmc2871668?pdf=render
https://pubmed.ncbi.nlm.nih.gov/20148031
https://nature.com/articles/nature08758
http://ui.adsabs.harvard.edu/abs/2010Natur.463..769T/abstract
https://europepmc.org/article/PMC/PMC2871668
https://experts.illinois.edu/en/publications/neural-bases-for-addictive-properties-of-benzodiazepines
https://www.nature.com/articles/nature08758.pdf
https://www.zora.uzh.ch/id/eprint/32067/
https://archive-ouverte.unige.ch/unige:10457

Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats

Autoři: Khom, Sophia Rodriguez, Larry Gandhi, Pauravi a další

Zdroj: Neurobiol Dis
Neurobiology of Disease, Vol 164, Iss, Pp 105610-(2022)

Témata: Male, Alcoholism/physiopathology, Neurosciences. Biological psychiatry. Neuropsychiatry, 301406 Neuropharmacology, Article, Alcohol use disorder, Rats, Sprague-Dawley, GABA, 03 medical and health sciences, Hormone Antagonists, Receptors, Glucocorticoid, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Glucocorticoid/antagonists & inhibitors, 301206 Pharmakologie, Receptors, Animals, Mifepristone/pharmacology, Central amygdala, Synaptic transmission, GABAergic Neurons, Glucocorticoid receptors, eIPSP, Synapses/drug effects, sIPSC, Amygdala, GABAergic Neurons/drug effects, Amygdala/drug effects, Rats, 3. Good health, Electrophysiology, Alcoholism, Mifepristone, Inhibitory Postsynaptic Potentials, SDG 3 – Gesundheit und Wohlergehen, Hormone Antagonists/pharmacology, Synapses, Inhibitory Postsynaptic Potentials/drug effects, 301406 Neuropharmakologie, Sprague-Dawley, 301206 Pharmacology, RC321-571

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34995754
https://doaj.org/article/3609dd49c37d4a49bd8fa7e78acfae86
https://ucrisportal.univie.ac.at/de/publications/03b4886b-3c6f-41a8-a8e6-5cbdde8d5653
https://doi.org/10.1016/j.nbd.2022.105610

Action of tachykinins in the hippocampus: Facilitation of inhibitory drive to GABAergic interneurons

Autoři: Ogier, R. Wrobel, Ludovic Raggenbass, Mario

Zdroj: Neuroscience, Vol. 156, No 3 (2008) pp. 527-36

Témata: 0301 basic medicine, 616.8, Gamma-Aminobutyric Acid/metabolism, Patch-Clamp Techniques, Tetrodotoxin/pharmacology, Patch-Clamp Techniques/methods, Action Potentials, Tetrodotoxin, In Vitro Techniques, Substance P, Action Potentials/drug effects, Oxytocin, Neural Inhibition/drug effects, Hippocampus, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Interneurons, Tachykinins, Anesthetics, Local/pharmacology, Animals, Pyramidal Cells/drug effects, Tachykinins/pharmacology, Anesthetics, Local, Receptors, Tachykinin, gamma-Aminobutyric Acid, Lysine/analogs & derivatives/metabolism, Lysine, Pyramidal Cells, Interneurons/drug effects, Neural Inhibition, Substance P/pharmacology, Oxytocin/pharmacology, Receptors, Tachykinin/agonists, ddc:616.8, Rats, Inhibitory Postsynaptic Potentials, Hippocampus/cytology, Inhibitory Postsynaptic Potentials/drug effects

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/18775478
http://www.sciencedirect.com/science/article/pii/S0306452208011767
https://europepmc.org/abstract/MED/18775478
https://archive-ouverte.unige.ch/unige:1687
https://www.sciencedirect.com/science/article/pii/S0306452208011767
https://core.ac.uk/display/60813123
https://www.ncbi.nlm.nih.gov/pubmed/18775478
https://archive-ouverte.unige.ch/unige:1687

GABAB Receptor Modulation of Feedforward Inhibition through Hippocampal Neurogliaform Cells

Autoři: Price, Christopher J Scott, Ricardo Rusakov, Dmitri A a další

Zdroj: Price, C J, Scott, R, Rusakov, D A & Capogna, M 2008, 'GABA(B) receptor modulation of feedforward inhibition through hippocampal neurogliaform cells', The Journal of neuroscience, vol. 28, no. 27, pp. 6974-82. https://doi.org/10.1523/JNEUROSCI.4673-07.2008

Témata: Phosphinic Acids/pharmacology, 0301 basic medicine, Baclofen, Calcium/metabolism, Synaptic Transmission/drug effects, Action Potentials, Action Potentials/drug effects, Baclofen/pharmacology, Neural Inhibition/drug effects, Hippocampus, GABA Antagonists, Propanolamines, 03 medical and health sciences, Organ Culture Techniques, Interneurons, Neural Pathways, Animals, Pyramidal Cells/drug effects, Calcium Signaling, gamma-Aminobutyric Acid/metabolism, GABA Agonists, Propanolamines/pharmacology, GABA Agonists/pharmacology, 0303 health sciences, Interneurons/cytology, Pyramidal Cells, Neural Inhibition, Neuroglia/drug effects, Receptors, GABA-A, Phosphinic Acids, Rats, GABA Antagonists/pharmacology, Inhibitory Postsynaptic Potentials, Receptors, GABA-B, Neural Pathways/cytology, Receptors, GABA-A/drug effects, Receptors, GABA-B/drug effects, Calcium Signaling/drug effects, Hippocampus/cytology, Inhibitory Postsynaptic Potentials/drug effects, Calcium, Neuroglia

Přístupová URL adresa: http://www.jneurosci.org/content/28/27/6974.full.pdf
https://pubmed.ncbi.nlm.nih.gov/18596171
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685170/
https://www.jneurosci.org/content/28/27/6974.full.pdf
https://www.jneurosci.org/content/28/27/6974
https://www.jneurosci.org/content/jneuro/28/27/6974.full.pdf
http://europepmc.org/articles/PMC2685170
https://www.neuroscience.ox.ac.uk/publications/257701
https://ora.ox.ac.uk/objects/uuid:a6b6a981-6d63-47fc-a846-312166449b11
https://doi.org/10.1523/jneurosci.4673-07.2008
https://pure.au.dk/portal/en/publications/c296874e-5566-4ec5-be57-59e6911f92f5
https://doi.org/10.1523/JNEUROSCI.4673-07.2008

Specific inhibitory synapses shift the balance from feedforward to feedback inhibition of hippocampal CA1 pyramidal cells

Autoři: Elfant, David Pál, Balázs Zoltán Emptage, Nigel a další

Zdroj: Elfant, D, Pál, B Z, Emptage, N & Capogna, M 2008, 'Specific inhibitory synapses shift the balance from feedforward to feedback inhibition of hippocampal CA1 pyramidal cells', The European journal of neuroscience, vol. 27, no. 1, pp. 104-13. https://doi.org/10.1111/j.1460-9568.2007.06001.x

Témata: Male, 0301 basic medicine, Patch-Clamp Techniques, Patch-Clamp Techniques/methods, In Vitro Techniques, Neural Inhibition/drug effects, Hippocampus, Feedback, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Interneurons, Animals, Feedback/drug effects, Pyramidal Cells/drug effects, Elméleti orvostudományok, 0303 health sciences, Synapses/drug effects, Pyramidal Cells, Interneurons/drug effects, Neural Inhibition, Orvostudományok, Electric Stimulation, Rats, Animals, Newborn, Inhibitory Postsynaptic Potentials, Synapses, Hippocampus/cytology, Inhibitory Postsynaptic Potentials/drug effects

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/18184315
https://pharm.ox.ac.uk/publications/186682
https://europepmc.org/article/MED/18184315
http://mrcanu.pharm.ox.ac.uk/sites/default/files/pdfs/elfant2008ejn.pdf
https://www.ncbi.nlm.nih.gov/pubmed/18184315
https://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2007.06001.x
https://www.neuroscience.ox.ac.uk/publications/186682
https://ora.ox.ac.uk/objects/uuid:2f4c5b68-87de-4351-a556-a45837d05f6e
https://doi.org/10.1111/j.1460-9568.2007.06001.x

Vasopressin modulates lateral septal network activity via two distinct electrophysiological mechanisms

Autoři: Allaman-Exertier, G. Reymond-Marron, I. Tribollet, Eliane a další

Zdroj: European Journal of Neuroscience, Vol. 26, No 9 (2007) pp. 2633-2642

Témata: 0301 basic medicine, Receptors, Vasopressin, 616.8, Gamma-Aminobutyric Acid/metabolism, Patch-Clamp Techniques, Vasopressins, Receptors, Vasopressin/agonists/antagonists & inhibitors/drug, Nerve Net/drug effects/*metabolism, Neural Inhibition/drug effects/physiology, Binding, Competitive, Synaptic Transmission, Rats, Sprague-Dawley, Radioligand Assay, 03 medical and health sciences, Neural Pathways/drug effects/*metabolism, Organ Culture Techniques, Binding, Competitive/drug effects/physiology, Neural Pathways, Neurons/drug effects/metabolism, Animals, Social Behavior, gamma-Aminobutyric Acid, Inhibitory Postsynaptic Potentials/drug effects/physiology, Neurons, 0303 health sciences, Septal Nuclei/drug effects/*metabolism, Vasopressins/pharmacology/*physiology, Neural Inhibition, ddc:616.8, Effects/*metabolism, Rats, Inhibitory Postsynaptic Potentials, Synaptic Transmission/drug effects/physiology, Septal Nuclei, Nerve Net, Antidiuretic Hormone Receptor Antagonists

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/17970727
https://archive-ouverte.unige.ch/unige:10160
https://core.ac.uk/display/60784895
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1460-9568.2007.05866.x
https://www.ncbi.nlm.nih.gov/pubmed/17970727
https://archive-ouverte.unige.ch/unige:10160
https://archive-ouverte.unige.ch/unige:10160
https://doi.org/10.1111/j.1460-9568.2007.05866.x

Unitary IPSPs enhance hilar mossy cell gain in the rat hippocampus

Autoři: Kerr, Angharad M Capogna, Marco

Zdroj: Kerr, A M & Capogna, M 2007, 'Unitary IPSPs enhance hilar mossy cell gain in the rat hippocampus', The Journal of Physiology, vol. 578, no. Pt 2, pp. 451-70. https://doi.org/10.1113/jphysiol.2006.121608

Témata: Male, 0301 basic medicine, Patch-Clamp Techniques, Tetrodotoxin/pharmacology, Synaptic Transmission/drug effects, Excitatory Postsynaptic Potentials/physiology, Mossy Fibers, Hippocampal/drug effects, Action Potentials, Action Potentials/drug effects, Electric Capacitance, Hippocampus, Rats, Sprague-Dawley, Bridged Bicyclo Compounds, 03 medical and health sciences, Interneurons, Quinoxalines, Electric Impedance, Pilocarpine/pharmacology, Animals, 2-Amino-5-phosphonovalerate/pharmacology, Neurons, 0303 health sciences, Cell Membrane/drug effects, Cell Membrane, Interneurons/drug effects, Pilocarpine, Excitatory Postsynaptic Potentials, Pyridazines/pharmacology, Neurons/drug effects, Quinoxalines/pharmacology, Rats, Pyridazines, 2-Amino-5-phosphonovalerate, Inhibitory Postsynaptic Potentials, Sodium Channels/physiology, Mossy Fibers, Hippocampal, Hippocampus/cytology, Inhibitory Postsynaptic Potentials/drug effects, Bridged Bicyclo Compounds/pharmacology

Přístupová URL adresa: https://physoc.onlinelibrary.wiley.com/doi/pdfdirect/10.1113/jphysiol.2006.121608
https://pubmed.ncbi.nlm.nih.gov/17082230
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075154
http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2006.121608/abstract
https://physoc.onlinelibrary.wiley.com/doi/pdf/10.1113/jphysiol.2006.121608
https://physoc.onlinelibrary.wiley.com/doi/10.1113/jphysiol.2006.121608
https://www.neuroscience.ox.ac.uk/publications/330481
https://ora.ox.ac.uk/objects/uuid:8e16f7a0-c7e4-4fed-8a43-423344f98ba0
https://doi.org/10.1113/jphysiol.2006.121608
https://pure.au.dk/portal/en/publications/51360683-26ad-4782-b845-8e8cac7c26df
https://doi.org/10.1113/jphysiol.2006.121608

Neural bases for addictive properties of benzodiazepines

Autoři: Tan, Kelly R. Brown, Matthew Labouebe, Gwenael Pierre a další

Zdroj: ISSN: 0028-0836 ; Nature, vol. 463, no. 7282 (2010) p. 769-774.

Témata: info:eu-repo/classification/ddc/616.8, Action Potentials/drug effects, Administration, Oral, Animals, Behavior, Addictive/ chemically induced/pathology/ physiopathology, Benzodiazepines/administration & dosage/ adverse effects/ pharmacology, Dopamine/metabolism, Electric Conductivity, Glutamic Acid/metabolism, Inhibitory Postsynaptic Potentials/drug effects/physiology, Interneurons/drug effects/metabolism, Mice, Inbred C57BL, Midazolam/administration & dosage/adverse effects/pharmacology, Models, Biological, Morphine/pharmacology, Neuronal Plasticity/drug effects, Neurons/ drug effects/metabolism, Organ Specificity, Receptors, AMPA/metabolism, GABA-A/deficiency/genetics/metabolism, Substrate Specificity, Ventral Tegmental Area/cytology/drug effects/metabolism, Gamma-Aminobutyric Acid/metabolism

Relation: info:eu-repo/semantics/altIdentifier/pmid/20148031; unige:10457

Dostupnost: https://archive-ouverte.unige.ch/unige:10457

GABA(B) receptor-mediated presynaptic inhibition of glycinergic transmission onto substantia gelatinosa neurons in the rat spinal cord

Autoři: Choi, In-Sun Cho, Jin-Hwa Jeong, Seok-Gwon a další

Přispěvatelé: Choi, In-Sun Cho, Jin-Hwa Jeong, Seok-Gwon a další

Témata: Animals, Baclofen/pharmacology, Glycine/antagonists & inhibitors/*physiology, Inhibitory Postsynaptic Potentials/drug effects/physiology, Neural Inhibition/drug effects/*physiology, Neurons/drug effects/physiology, Rats, Sprague-Dawley, Receptors, GABA-B/agonists/*physiology, Presynaptic/agonists/antagonists & inhibitors/*physiology, Spinal Cord/drug effects/physiology, Substantia Gelatinosa/drug effects/*physiology, Synaptic Transmission/drug effects/*physiology

Relation: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18258370; https://hdl.handle.net/10371/68121

Dostupnost: https://hdl.handle.net/10371/68121
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18258370
http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T0K-4RS9STC-5-W&_cdi=4865&_user=168665&_orig=search&_coverDate=08%2F31%2F2008&_sk=998619997&view=c&wchp=dGLbVtb-zSkzS&md5=1417ae4308c4809872c1bc4612164296&ie=/sdarticle.pdf
https://doi.org/10.1016/j.pain.2008.01.005