Výsledky vyhledávání - "Inhibitory Postsynaptic Potentials"

Longitudinal Excitation and Lamellar Feedforward Inhibition of the Hippocampal CA3 to CA1 Projections.

Autoři: Okamoto K Koike M Hioki H

Zdroj: Hippocampus [Hippocampus] 2025 Nov; Vol. 35 (6), pp. e70046.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE

Výrazy ze slovníku MeSH: CA1 Region, Hippocampal*/physiology , CA1 Region, Hippocampal*/cytology , CA3 Region, Hippocampal*/physiology , Excitatory Postsynaptic Potentials*/physiology , Neural Inhibition*/physiology , Inhibitory Postsynaptic Potentials*/physiology, Animals ; Male ; Channelrhodopsins ; Neural Pathways/physiology ; Interneurons/physiology ; Optogenetics ; Mice

Differential synaptic inhibition and serotonin 5-HT 7 receptor-mediated modulation in identified dorsal horn neurons.

Autoři: Salio C Ferrini F Bighinati A a další

Zdroj: Neurochemistry international [Neurochem Int] 2025 Sep; Vol. 188, pp. 106011. Date of Electronic Publication: 2025 Jun 18.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

Výrazy ze slovníku MeSH: Receptors, Serotonin*/metabolism , Receptors, Serotonin*/physiology , Posterior Horn Cells*/metabolism , Posterior Horn Cells*/drug effects , Posterior Horn Cells*/physiology , Neural Inhibition*/physiology , Neural Inhibition*/drug effects , Inhibitory Postsynaptic Potentials*/physiology , Inhibitory Postsynaptic Potentials*/drug effects , Synapses*, Animals ; Mice, Transgenic ; Mice ; Synaptic Transmission/physiology ; Male ; Vesicular Inhibitory Amino Acid Transport Proteins

Impairments in synaptic inhibition and glucose hypometabolism contribute to epileptogenesis in Wistar Audiogenic Rats with cortical malformation.

Autoři: Dos Santos FM de Lima TM Lazzarotto G a další

Zdroj: Neuroscience [Neuroscience] 2025 Aug 16; Vol. 581, pp. 164-178. Date of Electronic Publication: 2025 Jun 29.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

Výrazy ze slovníku MeSH: Glucose*/metabolism , Inhibitory Postsynaptic Potentials*/physiology , Malformations of Cortical Development*/metabolism , Malformations of Cortical Development*/physiopathology , Malformations of Cortical Development*/complications , Malformations of Cortical Development*/diagnostic imaging , Epilepsy, Reflex*/metabolism , Epilepsy, Reflex*/physiopathology , Cerebral Cortex*/metabolism , Cerebral Cortex*/physiopathology , Epilepsy*/metabolism , Epilepsy*/physiopathology , Neural Inhibition*/physiology, Animals ; Rats, Wistar ; Male ; Female ; Disease Models, Animal ; Positron-Emission Tomography ; Pyramidal Cells/physiology ; Pyramidal Cells/metabolism ; Rats ; Fluorodeoxyglucose F18 ; Animals, Newborn ; Brain/metabolism ; Brain/physiopathology

Enhanced amygdala inhibitory neurotransmission and its vulnerability to hyperthermic stress in Atp1a2 -deficient heterozygous mice.

Autoři: Satake S Yokota S Ikeda K

Zdroj: Journal of neurophysiology [J Neurophysiol] 2025 Jul 01; Vol. 134 (1), pp. 216-228. Date of Electronic Publication: 2025 Jun 04.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Sodium-Potassium-Exchanging ATPase*/genetics , Sodium-Potassium-Exchanging ATPase*/deficiency , Inhibitory Postsynaptic Potentials* , Hyperthermia*/physiopathology , Hyperthermia*/genetics , Synaptic Transmission* , Basolateral Nuclear Complex*/physiopathology , Basolateral Nuclear Complex*/physiology , Amygdala*/physiopathology, Animals ; Mice ; Excitatory Postsynaptic Potentials ; Heterozygote ; Male ; Mice, Knockout ; Neurons/physiology ; Mice, Inbred C57BL

Synaptic Drive onto Inhibitory and Excitatory Principal Neurons of the Mouse Lateral Superior Olive.

Autoři: Haragopal H Voytek MJ Winters BD

Zdroj: ENeuro [eNeuro] 2025 May 08; Vol. 12 (5). Date of Electronic Publication: 2025 May 08 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

Výrazy ze slovníku MeSH: Neurons*/physiology , Superior Olivary Complex*/physiology , Superior Olivary Complex*/cytology , Excitatory Postsynaptic Potentials*/physiology , Inhibitory Postsynaptic Potentials*/physiology , Neural Inhibition*/physiology , Synaptic Transmission*/physiology , Olivary Nucleus*/physiology, Animals ; Male ; Mice, Inbred C57BL ; Mice ; Patch-Clamp Techniques ; Female ; Mice, Transgenic ; Gene Knock-In Techniques ; Electric Stimulation

Dynamic changes of excitatory and inhibitory synapses in layer II/III of the primary motor cortex after peripheral nerve repair.

Autoři: Song J Yusufu A Sun J a další

Zdroj: Neuroscience [Neuroscience] 2025 Apr 19; Vol. 572, pp. 204-213. Date of Electronic Publication: 2025 Jan 31.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

Výrazy ze slovníku MeSH: Motor Cortex*/physiopathology , Peripheral Nerve Injuries*/physiopathology , Synapses*/physiology , Neuronal Plasticity*/physiology , Nerve Regeneration*/physiology , Excitatory Postsynaptic Potentials*/physiology , Inhibitory Postsynaptic Potentials*/physiology, Animals ; Male ; Rats, Sprague-Dawley ; Rats ; Recovery of Function/physiology ; Pyramidal Cells/physiology ; Median Nerve/injuries

Early postnatal GABAB antagonist treatment normalizes inhibitory/excitatory balance in neonatal Ts65Dn mice, a genetic model of down syndrome.

Autoři: Jin J Doan J Fernandez C a další

Zdroj: Experimental neurology [Exp Neurol] 2025 Apr; Vol. 386, pp. 115171. Date of Electronic Publication: 2025 Jan 29.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Down Syndrome*/genetics , Down Syndrome*/drug therapy , Down Syndrome*/physiopathology , Down Syndrome*/pathology , GABA-B Receptor Antagonists*/pharmacology , GABA-B Receptor Antagonists*/therapeutic use , Inhibitory Postsynaptic Potentials*/drug effects , Excitatory Postsynaptic Potentials*/drug effects , Excitatory Postsynaptic Potentials*/genetics , Excitatory Postsynaptic Potentials*/physiology , Neural Inhibition*/drug effects, Animals ; Mice ; Disease Models, Animal ; Animals, Newborn ; G Protein-Coupled Inwardly-Rectifying Potassium Channels/metabolism ; Mice, Transgenic ; Receptors, GABA-B/metabolism ; Hippocampus/drug effects ; Female ; Mice, Inbred C57BL ; Male

Distinct firing responses to synthetic synaptic currents in the adult murine reticular and relay thalamus.

Autoři: Chang IYM Paz JT

Zdroj: Journal of neurophysiology [J Neurophysiol] 2025 Apr 01; Vol. 133 (4), pp. 1329-1340. Date of Electronic Publication: 2025 Mar 25.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Excitatory Postsynaptic Potentials*/physiology , Neurons*/physiology , Inhibitory Postsynaptic Potentials*/physiology , Thalamus*/physiology , Action Potentials*/physiology, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Female ; Synapses/physiology

GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease.

Autoři: Netsyk O Korol SV Li JP a další

Zdroj: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Mar; Vol. 104 (2), pp. 420-428. Date of Electronic Publication: 2025 Feb 16.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE

Výrazy ze slovníku MeSH: Alzheimer Disease*/pathology , Alzheimer Disease*/physiopathology , Alzheimer Disease*/genetics , Dentate Gyrus*/drug effects , Dentate Gyrus*/physiopathology , Dentate Gyrus*/pathology , Inhibitory Postsynaptic Potentials*/drug effects , Inhibitory Postsynaptic Potentials*/physiology , gamma-Aminobutyric Acid*/pharmacology , gamma-Aminobutyric Acid*/metabolism , Aging* , Neurons*/drug effects , Neurons*/physiology, Animals ; Disease Models, Animal ; Mice, Transgenic ; Mice ; Patch-Clamp Techniques ; Male ; Insulin/pharmacology ; Amyloid beta-Protein Precursor/genetics ; Mice, Inbred C57BL ; Humans

Dorsomedial Striatum (DMS) CB1R Signaling Promotes Pavlovian Devaluation Sensitivity in Male Long Evans Rats and Reduces DMS Inhibitory Synaptic Transmission in Both Sexes.

Autoři: Stapf CA Keefer SE McInerney JM a další

Zdroj: ENeuro [eNeuro] 2025 Jan 29; Vol. 12 (1). Date of Electronic Publication: 2025 Jan 29 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

Výrazy ze slovníku MeSH: Receptor, Cannabinoid, CB1*/metabolism , Receptor, Cannabinoid, CB1*/agonists , Receptor, Cannabinoid, CB1*/antagonists & inhibitors , Conditioning, Classical*/physiology , Conditioning, Classical*/drug effects , Synaptic Transmission*/physiology , Synaptic Transmission*/drug effects , Inhibitory Postsynaptic Potentials*/physiology , Inhibitory Postsynaptic Potentials*/drug effects , Corpus Striatum*/drug effects , Corpus Striatum*/metabolism , Corpus Striatum*/physiology, Animals ; Male ; Female ; Rats, Long-Evans ; Rats ; Rimonabant/pharmacology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Sex Characteristics

Glyphosate impairs both structure and function of GABAergic synapses in hippocampal neurons.

Autoři: Chiantia G Comai D Hidisoglu E a další

Zdroj: Neuropharmacology [Neuropharmacology] 2025 Jan 01; Vol. 262, pp. 110183. Date of Electronic Publication: 2024 Oct 12.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

Výrazy ze slovníku MeSH: Glycine*/analogs & derivatives , Glycine*/pharmacology , Glyphosate* , Hippocampus*/drug effects , Hippocampus*/metabolism , Synapses*/drug effects , Inhibitory Postsynaptic Potentials*/drug effects , Inhibitory Postsynaptic Potentials*/physiology, Animals ; Mice ; Cells, Cultured ; GABAergic Neurons/drug effects ; GABAergic Neurons/metabolism ; Receptors, GABA-A/metabolism ; Receptors, GABA-A/drug effects ; Herbicides/toxicity ; Patch-Clamp Techniques ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism

Inhibitory Postsynaptic Potentials Participate in Intracellular and Extracellular Theta Rhythms in the Hippocampus: A Personal Narrative.

Autoři: Leung LS Yim CYC

Zdroj: Hippocampus [Hippocampus] 2025 Jan; Vol. 35 (1), pp. e23660.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE

Výrazy ze slovníku MeSH: Theta Rhythm*/physiology , Hippocampus*/physiology , Inhibitory Postsynaptic Potentials*/physiology, Animals ; Humans ; Pyramidal Cells/physiology

Release your inhibitions: The cell biology of GABAergic postsynaptic plasticity.

Autoři: Welle TM Smith KR

Zdroj: Current opinion in neurobiology [Curr Opin Neurobiol] 2025 Feb; Vol. 90, pp. 102952. Date of Electronic Publication: 2024 Dec 25.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Current Biology Country of Publication: England NLM ID: 9111376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6882 (Electronic) Linking ISSN: 09594388 NLM ISO Abbreviation: Curr Opin Neurobiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Neuronal Plasticity*/physiology , Neural Inhibition*/physiology , GABAergic Neurons*/physiology , Synapses*/physiology , Receptors, GABA-A*/metabolism , Inhibitory Postsynaptic Potentials*/physiology , gamma-Aminobutyric Acid*/metabolism, Animals ; Humans

Regulation of nociception by long-term potentiation of inhibitory postsynaptic currents from insular cortical parvalbumin-immunopositive neurons to pyramidal neurons.

Autoři: Kobayashi S Osaki H Kato S a další

Zdroj: Pain [Pain] 2025 Jan 21; Vol. 166 (8), pp. 1823-1835. Date of Electronic Publication: 2025 Jan 21.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7508686 Publication Model: Electronic Cited Medium: Internet ISSN: 1872-6623 (Electronic) Linking ISSN: 03043959 NLM ISO Abbreviation: Pain Subsets: MEDLINE

Výrazy ze slovníku MeSH: Parvalbumins*/metabolism , Long-Term Potentiation*/physiology , Nociception*/physiology , Inhibitory Postsynaptic Potentials*/physiology , Pyramidal Cells*/physiology , Pyramidal Cells*/metabolism , Insular Cortex*/cytology , Neurons*, Animals ; Rats ; Male ; Optogenetics ; Rats, Sprague-Dawley ; Rats, Transgenic

Altered synaptic functions in a humanized mouse model of down syndrome (TcMAC21): Implications for seizure susceptibility.

Autoři: Shao LR Stafstrom CE

Zdroj: Epilepsy research [Epilepsy Res] 2025 Dec; Vol. 218, pp. 107686. Date of Electronic Publication: 2025 Oct 17.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8703089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6844 (Electronic) Linking ISSN: 09201211 NLM ISO Abbreviation: Epilepsy Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Down Syndrome*/physiopathology , Down Syndrome*/genetics , Down Syndrome*/complications , Seizures*/physiopathology , Seizures*/genetics , Seizures*/etiology , Synapses*/physiology , Synapses*/drug effects, Animals ; Disease Models, Animal ; Mice ; Humans ; Neurons/physiology ; Neurons/drug effects ; Receptors, GABA-A/metabolism ; Patch-Clamp Techniques ; Mice, Transgenic ; Inhibitory Postsynaptic Potentials/drug effects ; Inhibitory Postsynaptic Potentials/physiology ; Kainic Acid/pharmacology ; Neocortex/physiopathology

Cannabinoids drive feeding through AgRP neurons.

Autoři: Yavuz Y Goren H Yilmaz B

Zdroj: Brain research [Brain Res] 2025 Oct 15; Vol. 1865, pp. 149857. Date of Electronic Publication: 2025 Jul 28.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Agouti-Related Protein*/metabolism , Agouti-Related Protein*/genetics , Neurons*/drug effects , Neurons*/physiology , Neurons*/metabolism , Cannabinoids*/pharmacology , Cannabinoids*/metabolism , Feeding Behavior*/physiology , Feeding Behavior*/drug effects, Animals ; Receptor, Cannabinoid, CB1/agonists ; Receptor, Cannabinoid, CB1/metabolism ; Receptor, Cannabinoid, CB1/antagonists & inhibitors ; Arcuate Nucleus of Hypothalamus/drug effects ; Arcuate Nucleus of Hypothalamus/metabolism ; Arcuate Nucleus of Hypothalamus/physiology ; Mice ; Male ; Eating/drug effects ; Eating/physiology ; Mice, Inbred C57BL ; Inhibitory Postsynaptic Potentials/drug effects ; Inhibitory Postsynaptic Potentials/physiology

Prenatal Exposure to MAM Impairs mPFC and Hippocampal Inhibitory Function in Mice during Adolescence and Adulthood.

Autoři: He Z He Q Tang X a další

Zdroj: ENeuro [eNeuro] 2024 Nov 14; Vol. 11 (11). Date of Electronic Publication: 2024 Nov 14 (Print Publication: 2024).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

Výrazy ze slovníku MeSH: Prenatal Exposure Delayed Effects*/physiopathology , Prenatal Exposure Delayed Effects*/chemically induced , Prefrontal Cortex*/drug effects , Prefrontal Cortex*/growth & development , Hippocampus*/drug effects , Hippocampus*/growth & development , Methylazoxymethanol Acetate*/toxicity , Inhibitory Postsynaptic Potentials*/drug effects , Inhibitory Postsynaptic Potentials*/physiology , Prepulse Inhibition*/drug effects , Prepulse Inhibition*/physiology , Pyramidal Cells*/drug effects , Pyramidal Cells*/physiology , Mice, Inbred C57BL*, Animals ; Female ; Pregnancy ; Male ; Schizophrenia/chemically induced ; Schizophrenia/physiopathology ; Parvalbumins/metabolism ; Disease Models, Animal ; Mice ; Neural Inhibition/drug effects ; Neural Inhibition/physiology ; Locomotion/drug effects ; Locomotion/physiology

Levofloxacin-induced seizure susceptibility involves both enhanced glutamatergic and impaired GABAergic synaptic function.

Autoři: He K He L Wei X a další

Zdroj: Brain research [Brain Res] 2025 Nov 01; Vol. 1866, pp. 149929. Date of Electronic Publication: 2025 Sep 05.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Seizures*/chemically induced , Seizures*/metabolism , Seizures*/physiopathology , Levofloxacin*/pharmacology , Levofloxacin*/toxicity, Animals ; Male ; Rats ; Rats, Sprague-Dawley ; Glutamic Acid/metabolism ; Synaptic Transmission/drug effects ; Synaptic Transmission/physiology ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Receptors, AMPA/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Vesicular Glutamate Transport Protein 1/metabolism ; Vesicular Inhibitory Amino Acid Transport Proteins/metabolism ; Inhibitory Postsynaptic Potentials/drug effects ; Synapses/drug effects ; Synapses/metabolism ; Pentylenetetrazole ; gamma-Aminobutyric Acid/metabolism ; Miniature Postsynaptic Potentials/drug effects ; GABAergic Neurons/drug effects ; GABAergic Neurons/metabolism ; Cerebral Cortex/metabolism ; Cerebral Cortex/drug effects ; Cells, Cultured

Altered Inhibitory Synaptic Transmission and Changes in GABAergic Markers in the Hippocampus of Genetic and Environmental Animal Model of Autism.

Autoři: Jurkovičová-Tarabová B Vargovič P Mihalj D a další

Zdroj: Neurochemical research [Neurochem Res] 2025 Oct 30; Vol. 50 (6), pp. 340. Date of Electronic Publication: 2025 Oct 30.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Hippocampus*/metabolism , Hippocampus*/physiopathology , Autistic Disorder*/genetics , Autistic Disorder*/metabolism , Autistic Disorder*/physiopathology , Synaptic Transmission*/physiology , GABAergic Neurons*/metabolism , gamma-Aminobutyric Acid*/metabolism, Animals ; Disease Models, Animal ; Female ; Inhibitory Postsynaptic Potentials/physiology ; Valproic Acid/toxicity ; Mice ; Male ; Pregnancy ; Rats ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Prenatal Exposure Delayed Effects ; Rats, Sprague-Dawley ; Microfilament Proteins

Propofol regulates arousal by enhancing inhibitory synaptic transmission of noradrenergic neurons in the locus coeruleus of adult male mice.

Autoři: Abe T Kurabe M Nakamura Y a další

Zdroj: Scientific reports [Sci Rep] 2025 Oct 28; Vol. 15 (1), pp. 37725. Date of Electronic Publication: 2025 Oct 28.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Propofol*/pharmacology , Locus Coeruleus*/drug effects , Locus Coeruleus*/physiology , Locus Coeruleus*/cytology , Synaptic Transmission*/drug effects , Adrenergic Neurons*/drug effects , Adrenergic Neurons*/physiology , Adrenergic Neurons*/metabolism , Arousal*/drug effects, Animals ; Male ; Mice ; Receptors, GABA-A/metabolism ; Action Potentials/drug effects ; Bicuculline/pharmacology ; Anesthetics, Intravenous/pharmacology ; Inhibitory Postsynaptic Potentials/drug effects