Výsledky vyhľadávania - "Immunotherapy"

Stem-like CD4+ T cells mediate T-cell state transitions to enhance tumor control and immunotherapy response.

Autori: Das M Kiruthiga C Kathiresan N a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Nov 14; Vol. 165, pp. 115432. Date of Electronic Publication: 2025 Aug 31.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/immunology , Neoplasms*/therapy , CD4-Positive T-Lymphocytes*/immunology , Immunotherapy*/methods, Humans ; Animals ; Tumor Microenvironment/immunology ; Immunotherapy, Adoptive/methods ; Immune Checkpoint Inhibitors/therapeutic use

Beyond CAR-T: Engineered NK cell therapies (CAR-NK, NKCEs) in next-generation cancer immunotherapy.

Autori: Zhang F Soleimani Samarkhazan H Pooraskari Z a ďalší

Zdroj: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2025 Oct; Vol. 214, pp. 104912. Date of Electronic Publication: 2025 Aug 21.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Immunotherapy*/methods , Immunotherapy*/trends , Killer Cells, Natural* , Neoplasms*/immunology , Neoplasms*/therapy, Humans ; Immunotherapy, Adoptive ; Receptors, Chimeric Antigen/therapeutic use ; Cell Engineering ; Receptors, Natural Killer Cell

Safety and immunogenicity of two Tau-targeting active immunotherapies, ACI-35.030 and JACI-35.054, in participants with early Alzheimer's disease: a phase 1b/2a, multicentre, double-blind, randomised, placebo-controlled study.

Autori: Sol O Mermoud J Hallikainen M a ďalší

Zdroj: EBioMedicine [EBioMedicine] 2025 Oct; Vol. 120, pp. 105940. Date of Electronic Publication: 2025 Sep 18.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Clinical Trial, Phase I

Informácie o časopise: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alzheimer Disease*/drug therapy , Alzheimer Disease*/immunology , Alzheimer Disease*/therapy , Alzheimer Disease*/metabolism , tau Proteins*/immunology , tau Proteins*/antagonists & inhibitors , tau Proteins*/metabolism , Immunotherapy, Active*/methods , Immunotherapy, Active*/adverse effects, Humans ; Male ; Female ; Aged ; Middle Aged ; Double-Blind Method ; Treatment Outcome ; Aged, 80 and over ; Immunotherapy

Engineered natural killer cells for cancer therapy.

Autori: Biederstädt A Rezvani K

Zdroj: Cancer cell [Cancer Cell] 2025 Nov 10; Vol. 43 (11), pp. 1987-2013. Date of Electronic Publication: 2025 Oct 23.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

Výrazy zo slovníka MeSH: Killer Cells, Natural*/immunology , Killer Cells, Natural*/transplantation , Neoplasms*/therapy , Neoplasms*/immunology , Immunotherapy, Adoptive*/methods , Cell Engineering*/methods, Humans ; Receptors, Chimeric Antigen/immunology ; Receptors, Chimeric Antigen/genetics ; Tumor Microenvironment/immunology ; Animals ; Immunotherapy/methods ; Gene Editing

Soil and Seed: Tumor Microenvironment Nurtures Immunotherapy Resistance and Renewal.

Autori: Li Y Feng Q Xia Y a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 30; Vol. 26 (21). Date of Electronic Publication: 2025 Oct 30.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tumor Microenvironment*/immunology , Neoplasms*/therapy , Neoplasms*/immunology , Neoplasms*/pathology , Immunotherapy*/methods , Drug Resistance, Neoplasm*, Humans ; Animals ; Immune Checkpoint Inhibitors/therapeutic use ; Immune Checkpoint Inhibitors/pharmacology ; Immunotherapy, Adoptive/methods

Senescent immune cells in the tumor microenvironment: emerging insights into cancer immunotherapy resistance.

Autori: Gao D Kan P He Y a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 17; Vol. 16, pp. 1656733. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tumor Microenvironment*/immunology , Neoplasms*/immunology , Neoplasms*/therapy , Neoplasms*/pathology , Cellular Senescence*/immunology , Immunotherapy*/methods , Drug Resistance, Neoplasm*/immunology, Humans ; Animals ; Immune Checkpoint Inhibitors/therapeutic use ; Immunotherapy, Adoptive

A review of immunotherapy for bone tumors.

Autori: Wang C Chen Z Mo H a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 09; Vol. 16, pp. 1580598. Date of Electronic Publication: 2025 Oct 09 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Bone Neoplasms*/therapy , Bone Neoplasms*/immunology , Immunotherapy*/methods, Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Cancer Vaccines/therapeutic use ; Cancer Vaccines/immunology ; Immunotherapy, Adoptive/methods ; Animals ; Combined Modality Therapy

Emerging strategies in colorectal cancer immunotherapy: enhancing efficacy and survival.

Autori: Zhang Y Guan H Feng X a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 02; Vol. 16, pp. 1616414. Date of Electronic Publication: 2025 Oct 02 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/immunology , Colorectal Neoplasms*/mortality , Immunotherapy*/methods, Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Cancer Vaccines/therapeutic use ; Oncolytic Virotherapy/methods ; Animals ; Combined Modality Therapy ; Immunotherapy, Adoptive ; Treatment Outcome

Emerging macrophage-based therapies for cancer: a review of preclinical and clinical advances.

Autori: Brancewicz J Kucharzewska P

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 02; Vol. 16, pp. 1679271. Date of Electronic Publication: 2025 Oct 02 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/therapy , Neoplasms*/immunology , Immunotherapy*/methods , Tumor-Associated Macrophages*/immunology , Tumor-Associated Macrophages*/metabolism , Tumor-Associated Macrophages*/transplantation , Macrophages*/immunology, Humans ; Animals ; Clinical Trials as Topic ; Immunotherapy, Adoptive/methods ; Extracellular Vesicles/immunology ; Tumor Microenvironment/immunology

Immunotherapy in Chronic Lymphocytic Leukemia.

Autori: Sworder B Siddiqi T

Zdroj: Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2025 Oct; Vol. 39 (5), pp. 981-995. Date of Electronic Publication: 2025 Jul 08.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Health Science Country of Publication: United States NLM ID: 8709473 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1977 (Electronic) Linking ISSN: 08898588 NLM ISO Abbreviation: Hematol Oncol Clin North Am Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leukemia, Lymphocytic, Chronic, B-Cell*/therapy , Leukemia, Lymphocytic, Chronic, B-Cell*/immunology , Immunotherapy*/methods , Antineoplastic Agents, Immunological*/therapeutic use, Humans ; Antibodies, Bispecific/therapeutic use ; Immunotherapy, Adoptive/methods

CD123-targeting immunotherapeutic approaches in acute myeloid leukaemia.

Autori: Dreyzin A Holtzman NG Bonifant CL

Zdroj: British journal of haematology [Br J Haematol] 2025 Oct; Vol. 207 (4), pp. 1178-1191. Date of Electronic Publication: 2025 Jul 24.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Leukemia, Myeloid, Acute*/therapy , Leukemia, Myeloid, Acute*/immunology , Leukemia, Myeloid, Acute*/drug therapy , Interleukin-3 Receptor alpha Subunit*/antagonists & inhibitors , Interleukin-3 Receptor alpha Subunit*/immunology , Immunotherapy*/methods , Antineoplastic Agents, Immunological*/therapeutic use, Humans ; Molecular Targeted Therapy ; Immunotherapy, Adoptive/methods ; Tumor Microenvironment ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Bispecific/therapeutic use

IL-21-reprogrammed Vδ1 T cells exert killing against solid tumors which is enhanced by CAR arming for off-the-shelf immunotherapy.

Autori: Portillo AL Mehboob M Snyder G a ďalší

Zdroj: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2562210. Date of Electronic Publication: 2025 Sep 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Interleukins*/immunology , Interleukins*/metabolism , Interleukins*/genetics , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Immunotherapy, Adoptive*/methods , Receptors, Antigen, T-Cell, gamma-delta*/immunology , Receptors, Antigen, T-Cell, gamma-delta*/metabolism , Neoplasms*/immunology , Neoplasms*/therapy , Breast Neoplasms*/immunology , Breast Neoplasms*/therapy , Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/therapy, Humans ; Animals ; Interleukin-21 ; Mice ; Female ; K562 Cells ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Cytotoxicity, Immunologic ; Tumor Microenvironment/immunology ; Lymphocyte Activation/immunology ; Immunotherapy/methods

IL-12 and GM-CSF engineered dendritic cells enhance the enrichment and selection of tumor-reactive T cells for cancer immunotherapy.

Autori: Liu Z Li H Gao Z a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Nov 17; Vol. 16, pp. 1684842. Date of Electronic Publication: 2025 Nov 17 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dendritic Cells*/immunology , Dendritic Cells*/metabolism , Granulocyte-Macrophage Colony-Stimulating Factor*/genetics , Granulocyte-Macrophage Colony-Stimulating Factor*/metabolism , Granulocyte-Macrophage Colony-Stimulating Factor*/immunology , Interleukin-12*/genetics , Interleukin-12*/metabolism , Interleukin-12*/immunology , Neoplasms*/therapy , Neoplasms*/immunology , Immunotherapy, Adoptive*/methods, Animals ; Mice ; Humans ; Antigens, Neoplasm/immunology ; Lymphocyte Activation/immunology ; Lymphocytes, Tumor-Infiltrating/immunology ; Cell Line, Tumor ; Mice, Inbred C57BL ; Immunotherapy/methods

Pluripotent stem cell-derived chimeric antigen receptor-natural killer cells targeting epidermal growth factor receptor 2 for cancer immunotherapy.

Autori: Han J Jin C Hwang SB a ďalší

Zdroj: BMB reports [BMB Rep] 2025 Nov; Vol. 58 (11), pp. 475-483.

Spôsob vydávania: Journal Article; News

Informácie o časopise: Publisher: Korean Society for Biochemistry and Molecular Biology Country of Publication: Korea (South) NLM ID: 101465334 Publication Model: Print Cited Medium: Internet ISSN: 1976-670X (Electronic) Linking ISSN: 19766696 NLM ISO Abbreviation: BMB Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Killer Cells, Natural*/immunology , Killer Cells, Natural*/metabolism , Killer Cells, Natural*/cytology , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptor, ErbB-2*/immunology , Receptor, ErbB-2*/metabolism , Immunotherapy*/methods , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/metabolism , Pluripotent Stem Cells*/immunology , Neoplasms*/therapy , Neoplasms*/immunology, Humans ; Cell Line, Tumor ; Immunotherapy, Adoptive/methods ; Cell Differentiation

Incorporating mRNA therapeutics into biological treatments of hematologic malignancies.

Autori: Hunia J Tomasik J Czerwik N a ďalší

Zdroj: Frontiers in immunology [Front Immunol] 2025 Oct 22; Vol. 16, pp. 1680071. Date of Electronic Publication: 2025 Oct 22 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Hematologic Neoplasms*/therapy , Hematologic Neoplasms*/immunology , Hematologic Neoplasms*/genetics , RNA, Messenger*/genetics , RNA, Messenger*/therapeutic use , Immunotherapy, Adoptive*/methods, Humans ; Animals ; Antibodies, Bispecific/therapeutic use ; Antibodies, Bispecific/genetics ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal/genetics ; Receptors, Chimeric Antigen/genetics ; Receptors, Chimeric Antigen/immunology ; Immunotherapy/methods

Immune-based cancer therapies: mechanistic insights, clinical progress, and future directions.

Autori: Devaraji M Varghese Cheriyan B

Zdroj: Journal of the Egyptian National Cancer Institute [J Egypt Natl Canc Inst] 2025 Sep 29; Vol. 37 (1), pp. 62. Date of Electronic Publication: 2025 Sep 29.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: SpringerOpen Country of Publication: England NLM ID: 9424566 Publication Model: Electronic Cited Medium: Internet ISSN: 2589-0409 (Electronic) Linking ISSN: 11100362 NLM ISO Abbreviation: J Egypt Natl Canc Inst Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/therapy , Neoplasms*/immunology , Immunotherapy*/methods , Immunotherapy*/trends, Humans ; Cancer Vaccines/therapeutic use ; Cancer Vaccines/immunology ; Immune Checkpoint Inhibitors/therapeutic use ; Oncolytic Virotherapy/methods ; Immunotherapy, Adoptive/methods

Cytokine release syndrome in solid tumors.

Autori: Synnott D O'Reilly D De Freitas D a ďalší

Zdroj: Cancer [Cancer] 2025 Sep 01; Vol. 131 (17), pp. e70069.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/immunology , Neoplasms*/therapy , Neoplasms*/complications , Cytokine Release Syndrome*/therapy , Cytokine Release Syndrome*/etiology , Cytokine Release Syndrome*/diagnosis , Cytokine Release Syndrome*/immunology , Immunotherapy*/adverse effects , Immunotherapy*/methods, Humans ; Tumor Microenvironment/immunology ; Immunotherapy, Adoptive/adverse effects

Mechanisms, advances, and challenges of immunotherapy in gastric cancer.

Autori: Wang Z Wang T

Zdroj: Frontiers in immunology [Front Immunol] 2025 Sep 04; Vol. 16, pp. 1639487. Date of Electronic Publication: 2025 Sep 04 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Stomach Neoplasms*/therapy , Stomach Neoplasms*/immunology , Stomach Neoplasms*/metabolism , Immunotherapy*/methods , Immune Checkpoint Inhibitors*/therapeutic use, Humans ; Tumor Microenvironment/immunology ; Cancer Vaccines/therapeutic use ; Cancer Vaccines/immunology ; Immunotherapy, Adoptive/methods ; Animals ; Biomarkers, Tumor

Exploiting TCR Repertoire Analysis to Select Therapeutic TCRs for Cancer Immunotherapy.

Autori: Demaël UM Rirkkrai T Okus FZ a ďalší

Zdroj: Cells [Cells] 2025 Aug 07; Vol. 14 (15). Date of Electronic Publication: 2025 Aug 07.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/therapy , Neoplasms*/immunology , Receptors, Antigen, T-Cell*/metabolism , Receptors, Antigen, T-Cell*/immunology , Receptors, Antigen, T-Cell*/genetics , Immunotherapy*/methods, Humans ; Immunotherapy, Adoptive/methods ; T-Lymphocytes/immunology ; Animals ; Antigens, Neoplasm/immunology

Recharging aged-CAR with NAD ⁺ to boost immunotherapy.

Autori: Fan G Wang Y Wang R

Zdroj: Trends in cancer [Trends Cancer] 2025 Aug; Vol. 11 (8), pp. 711-712. Date of Electronic Publication: 2025 Jun 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 101665956 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-8025 (Electronic) Linking ISSN: 24058025 NLM ISO Abbreviation: Trends Cancer Subsets: MEDLINE

Výrazy zo slovníka MeSH: NAD*/metabolism , Neoplasms*/immunology , Neoplasms*/therapy , Receptors, Chimeric Antigen*/metabolism , Receptors, Chimeric Antigen*/immunology , Immunotherapy, Adoptive*/methods, Humans ; Immunosenescence/immunology ; Immunosenescence/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Aged ; Aging/immunology ; Immunotherapy/methods