Suchergebnisse - "Immunoglobulins"

A Multicentric Clinical Study to Evaluate Pharmacokinetics, Efficacy, and Safety of Immune Globulin Subcutaneous 20% Weekly/Biweekly Dosing in Treatment-Experienced Patients and Loading/Weekly Maintenance Dosing in Treatment-Naïve Patients with Primary Immunodeficiency.

Autoren: Lumry WR Palumbo M Hsu C et al.

Quelle: Journal of clinical immunology [J Clin Immunol] 2025 Nov 12; Vol. 45 (1), pp. 158. Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Equivalence Trial; Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Springer Country of Publication: Netherlands NLM ID: 8102137 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2592 (Electronic) Linking ISSN: 02719142 NLM ISO Abbreviation: J Clin Immunol Subsets: MEDLINE

MeSH-Schlagworte: Immunoglobulins*/administration & dosage , Immunologic Deficiency Syndromes*/drug therapy , Primary Immunodeficiency Diseases*/drug therapy, Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Drug Administration Schedule ; Immunoglobulins, Intravenous/administration & dosage ; Immunoglobulins, Intravenous/pharmacokinetics ; Injections, Subcutaneous ; Treatment Outcome

Revisiting the Biological Rationale for Cytomegalovirus Immune Globulin (CMVIG) in the Modern Era of Solid Organ Transplantation: Current State and Future Direction.

Autoren: Campbell A Pruett TL

Quelle: Transplantation proceedings [Transplant Proc] 2025 Oct; Vol. 57 (8), pp. 1610-1620. Date of Electronic Publication: 2025 Sep 12.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE

MeSH-Schlagworte: Organ Transplantation*/adverse effects , Cytomegalovirus Infections*/prevention & control , Cytomegalovirus Infections*/immunology , Cytomegalovirus Infections*/virology , Immunoglobulins*/therapeutic use , Cytomegalovirus*/immunology , Cytomegalovirus*/drug effects, Humans ; Antiviral Agents/therapeutic use ; Immunosuppressive Agents/adverse effects ; Immunoglobulins, Intravenous

Efficacy of Subcutaneous Immunoglobulin in the Postoperative Management After Pediatric Living Donor Liver Transplantation.

Autoren: Hirata Y Sanada Y Takadera K et al.

Quelle: Pediatric transplantation [Pediatr Transplant] 2025 Aug; Vol. 29 (5), pp. e70115.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9802574 Publication Model: Print Cited Medium: Internet ISSN: 1399-3046 (Electronic) Linking ISSN: 13973142 NLM ISO Abbreviation: Pediatr Transplant Subsets: MEDLINE

MeSH-Schlagworte: Liver Transplantation* , Postoperative Complications*/prevention & control , Postoperative Care*/methods , Agammaglobulinemia*/drug therapy , Agammaglobulinemia*/therapy , Immunoglobulins*/administration & dosage, Humans ; Male ; Female ; Living Donors ; Child, Preschool ; Child ; Infant ; Retrospective Studies ; Adolescent ; Immunoglobulins, Intravenous/administration & dosage ; Immunoglobulins, Intravenous/therapeutic use ; Treatment Outcome ; Immunoglobulin G/blood ; Injections, Subcutaneous

Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway.

Autoren: Rechtman A Zveik O Shweiki L et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Jul 24; Vol. 16, pp. 1620069. Date of Electronic Publication: 2025 Jul 24 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Antigens, CD*/blood , Antigens, CD*/immunology , Antigens, CD*/genetics , Immune Tolerance* , Immunoglobulins*/blood , Immunoglobulins*/immunology , Immunoglobulins*/genetics , Membrane Glycoproteins*/blood , Membrane Glycoproteins*/immunology , Membrane Glycoproteins*/genetics , Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease*/blood , Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease*/diagnosis , Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease*/genetics , Neuromyelitis Optica*/immunology , Neuromyelitis Optica*/drug therapy , Neuromyelitis Optica*/blood , Neuromyelitis Optica*/diagnosis, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Autoantibodies/immunology ; Autoantibodies/blood ; Biomarkers/blood ; CD83 Antigen ; Immunoglobulins, Intravenous/therapeutic use ; Immunosuppressive Agents/therapeutic use ; Recurrence

Рrospective multicenter study of treatment efficacy, safety, and quality of life in a large cohort of patients with inborn errors of immunity receiving subcutaneous immunoglobulin by the rapid push method.

Autoren: Avedova A Deripapa E Rodina Y et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Jul 22; Vol. 16, pp. 1598491. Date of Electronic Publication: 2025 Jul 22 (Print Publication: 2025).

Publikationsart: Journal Article; Multicenter Study; Observational Study

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Quality of Life* , Immunoglobulins*/administration & dosage, Humans ; Male ; Female ; Child, Preschool ; Child ; Adult ; Adolescent ; Young Adult ; Middle Aged ; Infant ; Treatment Outcome ; Immunoglobulins, Intravenous/administration & dosage ; Immunoglobulins, Intravenous/adverse effects ; Immunoglobulin G/blood ; Immunoglobulin G/administration & dosage ; Infusions, Subcutaneous ; Aged ; Injections, Subcutaneous ; Primary Immunodeficiency Diseases

Bridging the Gap in Secondary Antibody Deficiencies: Current Evidence and Unmet Needs in Diagnosis and Management with Immunoglobulin Replacement.

Autoren: Kan AKC Chan BCY Lau CS et al.

Quelle: Clinical reviews in allergy & immunology [Clin Rev Allergy Immunol] 2025 Dec 06; Vol. 68 (1), pp. 106. Date of Electronic Publication: 2025 Dec 06.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 9504368 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0267 (Electronic) Linking ISSN: 10800549 NLM ISO Abbreviation: Clin Rev Allergy Immunol Subsets: MEDLINE

MeSH-Schlagworte: Immunoglobulins, Intravenous*/therapeutic use , Immunologic Deficiency Syndromes*/diagnosis , Immunologic Deficiency Syndromes*/therapy , Immunoglobulins*/therapeutic use, Humans ; Disease Management ; Quality of Life ; Immunization, Passive

Neural Immunoglobulins Shape Brain Circuits.

Autoren: Salzet M; Univ. Lille, Inserm, CHU Lille, U1192-Protéomique Réponse Inflammatoire Spectrométrie de Masse-PRISM, Lille, France.; Institut Universitaire de France, Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation, Paris, France.

Quelle: The European journal of neuroscience [Eur J Neurosci] 2025 Nov; Vol. 62 (10), pp. e70330.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print Cited Medium: Internet ISSN: 1460-9568 (Electronic) Linking ISSN: 0953816X NLM ISO Abbreviation: Eur J Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Brain*/immunology , Brain*/metabolism , Neurons*/immunology , Neurons*/metabolism , Immunoglobulins*/metabolism , Immunoglobulins*/immunology, Humans ; Animals ; Microglia/immunology ; Astrocytes/immunology

Very High Dose Immunoglobulin Treatment for Chronic Inflammatory Demyelinating Polyneuropathy: A Multicentre UK Study.

Autoren: Rajabally YA Freiha J Min YG et al.

Quelle: European journal of neurology [Eur J Neurol] 2025 Nov; Vol. 32 (11), pp. e70429.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE

MeSH-Schlagworte: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating*/drug therapy , Immunologic Factors*/administration & dosage , Immunologic Factors*/therapeutic use , Immunoglobulins, Intravenous*/administration & dosage , Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/adverse effects , Immunoglobulins*/administration & dosage , Immunoglobulins*/therapeutic use , Immunoglobulins*/adverse effects, Humans ; Male ; Female ; United Kingdom ; Middle Aged ; Retrospective Studies ; Aged ; Treatment Outcome ; Adult ; Aged, 80 and over

Immunoglobulin for myasthenia gravis.

Autoren: Manolopoulos A Alzuabi M Elmashala A et al.

Quelle: The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2025 Oct 15; Vol. 10. Cochrane AN: CD013801. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis; Review

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 100909747 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-493X (Electronic) Linking ISSN: 13616137 NLM ISO Abbreviation: Cochrane Database Syst Rev Subsets: MEDLINE

MeSH-Schlagworte: Myasthenia Gravis*/drug therapy , Myasthenia Gravis*/therapy , Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/adverse effects , Immunoglobulins, Intravenous*/administration & dosage , Immunoglobulins*/therapeutic use , Immunoglobulins*/adverse effects, Humans ; Randomized Controlled Trials as Topic ; Quality of Life ; Injections, Subcutaneous ; Bias ; Plasma Exchange ; Cholinesterase Inhibitors/therapeutic use

Intravenous Efgartigimod or Intravenous Immunoglobulin in Guillain-Barre Syndrome: An Observational Multicenter Study.

Autoren: Cai H Zhou F Li T et al.

Quelle: Journal of the peripheral nervous system : JPNS [J Peripher Nerv Syst] 2025 Dec; Vol. 30 (4), pp. e70072.

Publikationsart: Journal Article; Multicenter Study; Observational Study; Comparative Study

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 9704532 Publication Model: Print Cited Medium: Internet ISSN: 1529-8027 (Electronic) Linking ISSN: 10859489 NLM ISO Abbreviation: J Peripher Nerv Syst Subsets: MEDLINE

MeSH-Schlagworte: Guillain-Barre Syndrome*/drug therapy , Immunoglobulins, Intravenous*/administration & dosage , Immunoglobulins, Intravenous*/pharmacology , Immunoglobulins, Intravenous*/therapeutic use , Immunologic Factors*/administration & dosage , Immunologic Factors*/pharmacology, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; Young Adult ; Receptors, Fc/antagonists & inhibitors ; Treatment Outcome

Targeted blockade of IL-23 receptor by engineered IgY antibody attenuates bacterial enteritis via reprogramming gut microbiota-immune axis in grass carp (Ctenopharyngodon idella).

Autoren: Hu X Meng P Han P et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 334 (Pt 1), pp. 148967. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Carps*/immunology , Carps*/microbiology , Gastrointestinal Microbiome*/drug effects , Gastrointestinal Microbiome*/immunology , Immunoglobulins*/immunology , Immunoglobulins*/pharmacology , Immunoglobulins*/genetics , Enteritis*/microbiology , Enteritis*/immunology , Enteritis*/veterinary , Fish Diseases*/immunology , Fish Diseases*/microbiology, Animals ; Aeromonas hydrophila ; Chickens ; Protein Engineering

Thyroid autoantibodies in paediatric thyroid eye disease patients in an Australian population.

Autoren: Wang DD Sullivan TJ

Quelle: Orbit (Amsterdam, Netherlands) [Orbit] 2025 Dec; Vol. 44 (6), pp. 689-697. Date of Electronic Publication: 2025 Feb 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8301221 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5108 (Electronic) Linking ISSN: 01676830 NLM ISO Abbreviation: Orbit Subsets: MEDLINE

MeSH-Schlagworte: Graves Ophthalmopathy*/immunology , Graves Ophthalmopathy*/epidemiology , Graves Ophthalmopathy*/diagnosis , Graves Ophthalmopathy*/blood , Autoantibodies*/blood , Autoantibodies*/immunology , Immunoglobulins, Thyroid-Stimulating*/blood , Immunoglobulins, Thyroid-Stimulating*/immunology, Humans ; Child ; Female ; Male ; Retrospective Studies ; Child, Preschool ; Adolescent ; Australia/epidemiology

Comparing the efficacy of efgartigimod and intravenous immunoglobulin on AQP4-IgG-positive neuromyelitis optica spectrum disorder during acute attacks.

Autoren: Liu J Li M Wu H et al.

Quelle: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Dec; Vol. 91 (12), pp. 3521-3528. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Neuromyelitis Optica*/drug therapy , Neuromyelitis Optica*/immunology , Neuromyelitis Optica*/blood , Aquaporin 4*/immunology , Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/administration & dosage, Humans ; Male ; Female ; Retrospective Studies ; Adult ; Middle Aged ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Case-Control Studies ; Treatment Outcome ; Young Adult ; Acute Disease ; Disability Evaluation ; Follow-Up Studies

Oral feeding of egg yolk antibody provide passive immune protection against largemouth bass iridovirus.

Autoren: Cao J Liu S Luo J et al.

Quelle: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Dec; Vol. 167, pp. 110898. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH-Schlagworte: Immunoglobulins*/administration & dosage , Immunoglobulins*/immunology , Bass*/immunology , Fish Diseases*/immunology , Fish Diseases*/prevention & control , Fish Diseases*/virology , Egg Yolk*/immunology , Antibodies, Viral*/administration & dosage , Antibodies, Viral*/immunology , DNA Virus Infections*/veterinary , DNA Virus Infections*/prevention & control , DNA Virus Infections*/immunology , DNA Virus Infections*/virology , Iridovirus*/physiology , Iridovirus*/immunology , Immunization, Passive*/veterinary, Animals ; Administration, Oral ; Animal Feed/analysis

Effectiveness of antenatal intravenous immunoglobulin treatment in recurrent fetal and neonatal alloimmune thrombocytopenia.

Autoren: Zloto K Cohen S Batsry L et al.

Quelle: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology [Ultrasound Obstet Gynecol] 2025 Dec; Vol. 66 (6), pp. 773-780. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley & Sons, Ltd Country of Publication: England NLM ID: 9108340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0705 (Electronic) Linking ISSN: 09607692 NLM ISO Abbreviation: Ultrasound Obstet Gynecol Subsets: MEDLINE

MeSH-Schlagworte: Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/administration & dosage , Thrombocytopenia, Neonatal Alloimmune*/drug therapy , Prenatal Care*/methods , Fetal Diseases*/drug therapy , Immunologic Factors*/administration & dosage , Immunologic Factors*/therapeutic use, Humans ; Female ; Pregnancy ; Retrospective Studies ; Adult ; Infant, Newborn ; Treatment Outcome ; Recurrence ; Platelet Count ; Pregnancy Outcome

Asymmetric dimethylarginine as a predictive marker for resistance to high-dose intravenous immunoglobulin in Kawasaki disease.

Autoren: Ishii M Taku K Kojiro M et al.

Quelle: European journal of pediatrics [Eur J Pediatr] 2025 Nov 20; Vol. 184 (12), pp. 776. Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE

MeSH-Schlagworte: Mucocutaneous Lymph Node Syndrome*/blood , Mucocutaneous Lymph Node Syndrome*/drug therapy , Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/administration & dosage , Arginine*/analogs & derivatives , Arginine*/blood , Drug Resistance* , Immunologic Factors*/therapeutic use, Humans ; Male ; Female ; Prospective Studies ; Biomarkers/blood ; Child, Preschool ; Infant ; Child ; Treatment Outcome ; Predictive Value of Tests

R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.

Autoren: Sun K Li R Xu T et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Nov 19; Vol. 16, pp. 1722358. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Kidney Neoplasms*/immunology , Kidney Neoplasms*/pathology , Kidney Neoplasms*/genetics , Kidney Neoplasms*/metabolism , Kidney Neoplasms*/mortality , Carcinoma, Renal Cell*/immunology , Carcinoma, Renal Cell*/pathology , Carcinoma, Renal Cell*/genetics , Carcinoma, Renal Cell*/metabolism , Carcinoma, Renal Cell*/mortality , Immunoglobulins*/genetics , Immunoglobulins*/metabolism , Immunoglobulins*/immunology, Humans ; Tumor Microenvironment/immunology ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Prognosis ; Immunomodulation ; Epithelial-Mesenchymal Transition ; Biomarkers, Tumor/genetics

Intravenous immunoglobulin and prednisolone to women with unexplained recurrent pregnancy loss after assisted reproductive technology treatment: a randomised, double-blind, placebo-controlled trial.

Autoren: Nørgaard-Pedersen C Kesmodel US Jørgensen MM et al.

Quelle: BMJ open [BMJ Open] 2025 Nov 19; Vol. 15 (11), pp. e106024. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

MeSH-Schlagworte: Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/administration & dosage , Abortion, Habitual*/drug therapy , Abortion, Habitual*/prevention & control , Prednisolone*/administration & dosage , Prednisolone*/therapeutic use , Reproductive Techniques, Assisted*/adverse effects, Humans ; Female ; Pregnancy ; Double-Blind Method ; Adult ; Young Adult ; Pregnancy Rate ; Pregnancy Outcome

`Integrated multi-modal dissection of IVIg-mediated immune reprogramming in lupus mice.

Autoren: Yuan X Sun P Wang T et al.

Quelle: Life sciences [Life Sci] 2025 Nov 15; Vol. 381, pp. 123997. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Lupus Erythematosus, Systemic*/immunology , Lupus Erythematosus, Systemic*/drug therapy , Lupus Erythematosus, Systemic*/pathology , Immunoglobulins, Intravenous*/pharmacology , Immunoglobulins, Intravenous*/therapeutic use, Animals ; Mice ; Mice, Inbred MRL lpr ; Female ; Spleen/immunology ; Spleen/drug effects ; Spleen/pathology ; B-Lymphocytes/immunology ; B-Lymphocytes/drug effects ; Autoantibodies/immunology ; Proteomics/methods ; Disease Models, Animal ; Dendritic Cells/immunology ; Dendritic Cells/drug effects

Fc-Modified IVIG with Enhanced Blood-Brain Barrier Penetration Ameliorates Cognitive Deficits and Neuropathology in A53T α-Synuclein Transgenic Mice.

Autoren: Zhu J Huang YR Wang MQ et al.

Quelle: Cellular and molecular neurobiology [Cell Mol Neurobiol] 2025 Nov 14; Vol. 45 (1), pp. 103. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Netherlands NLM ID: 8200709 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6830 (Electronic) Linking ISSN: 02724340 NLM ISO Abbreviation: Cell Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: alpha-Synuclein*/genetics , alpha-Synuclein*/metabolism , Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Immunoglobulins, Intravenous*/pharmacology , Immunoglobulins, Intravenous*/therapeutic use , Immunoglobulins, Intravenous*/pharmacokinetics , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/pathology , Immunoglobulin Fc Fragments*, Animals ; Mice, Transgenic ; Mice ; Oxidative Stress/drug effects ; Mice, Inbred C57BL ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology ; Parkinson Disease/pathology ; Parkinson Disease/drug therapy ; Humans