Suchergebnisse - "Immunity protein"

Differential crosstalk between toxin-immunity protein homologs divides Myxococcus nonself siblings into close and distant social relatives

Autoren: Feng Wang Jing Luo Zheng Zhang et al.

Quelle: mBio
mBio, Vol 16, Iss 5 (2025)

Schlagwörter: close and distant relationship, Myxococcus xanthus, toxin–immunity protein system, multiple homologous pairs, kin discrimination, cross-immunity, Microbiology, QR1-502, Research Article

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40152585
https://doaj.org/article/98cbd6d8e1d146bf862e79f9a02a2c9d

Xanthomonas immunity proteins protect against the cis-toxic effects of their cognate T4SS effectors

Autoren: Gabriel Umaji Oka Diorge P. Souza Germán G. Sgro et al.

Quelle: EMBO Rep

Schlagwörter: 0301 basic medicine, Cell biology, Xanthomonas, Cell envelope, Immunology, Plant Science, Microbiology, Biochemistry, Gene, Article, Type IV Secretion Systems, Agricultural and Biological Sciences, 03 medical and health sciences, Endocrinology, Bacterial Biofilms and Quorum Sensing Mechanisms, Bacterial Proteins, TYPE IV SECRETION SYSTEM, Biochemistry, Genetics and Molecular Biology, Escherichia coli, Genetics, Humans, CIS-INTOXICATION, Molecular Biology, Biology, Secretion, 0303 health sciences, Dynamics and Pathogenesis of Cholera Bacteria, Bacteria, FOS: Clinical medicine, Genomics and Pathogenicity of Plant Pathogenic Bacteria, Immunity, Life Sciences, Effector Proteins, Anti-Bacterial Agents, 3. Good health, Immune system, FOS: Biological sciences, Effector, BIOFILM, IMMUNITY PROTEIN

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38332152
http://hdl.handle.net/11336/260583

Identification of atypical T4SS effector proteins mediating bacterial defense

Autoren: Xi Shen Zixiang Yang Zihan Li et al.

Weitere Verfasser: Xi Shen Zixiang Yang Zihan Li et al.

Quelle: mLife
mLife, Vol 2, Iss 3, Pp 295-307 (2023)

Schlagwörter: 0301 basic medicine, 0303 health sciences, atypical effectors, toxic, Microbiology, QR1-502, Immunity protein, defense, T4SS, 03 medical and health sciences, Medicine, Health and Life Sciences, Atypical effectors, immunity protein, Original Research

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38817810
https://doaj.org/article/99cda5f750344fdbbd055c8d4d2ef9a6
https://hdl.handle.net/10356/173615

Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii

Autoren: Nicolas Flaugnatti Loriane Bader Mary Croisier-Coeytaux et al.

Quelle: eLife, Vol 14 (2025)

Schlagwörter: Acinetobacter baumannii, capsular polysaccharide, immunity protein-independent protection, type VI secretion, Medicine, Science, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: https://elifesciences.org/articles/101032; https://doaj.org/toc/2050-084X

Zugangs-URL: https://doaj.org/article/d7708703a81f4bfa9b0d8854c93583f3

The uncropped western blots and gel electrophoresis images shown in figures can be found in this dataset.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Relation: https://figshare.com/articles/journal_contribution/The_uncropped_western_blots_and_gel_electrophoresis_images_shown_in_figures_can_be_found_in_this_dataset_/29160713

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.s021
https://figshare.com/articles/journal_contribution/The_uncropped_western_blots_and_gel_electrophoresis_images_shown_in_figures_can_be_found_in_this_dataset_/29160713

Genomic analysis of Salmonella isolated from surface water and animal sources in Chile reveals new T6SS effector protein candidates

Autoren: Fernando A. Amaya Carlos J. Blondel Felipe Reyes-Méndez et al.

Quelle: Front Microbiol
Frontiers in Microbiology, Vol 15 (2024)

Schlagwörter: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, T6SS, effector, Salmonella, Chile, immunity protein, Microbiology, QR1-502

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39723139
https://doaj.org/article/9d7b75d85557489d9a762e54aaf94255

Pseudomonas aeruginosa Soluble Pyocins as Antibacterial Weapons

Autoren: Cornelis, Pierre Dingemans, Jozef Baysse, Christine et al.

Weitere Verfasser: Cornelis, Pierre Dingemans, Jozef Baysse, Christine et al.

Quelle: Methods in Molecular Biology ISBN: 9781071634721

Schlagwörter: Pyocins, Anti-Bacterial Agents/chemistry, S6, Bacteriocins/metabolism, S3, S5, S4, Anti-Bacterial Agents, 3. Good health, Pseudomonas aeruginosa/metabolism, Immunity protein, [SDV] Life Sciences [q-bio], Bacteriocins, Pseudomonas Infections/drug therapy, Pyocins S2, Escherichia coli/metabolism, Pseudomonas aeruginosa, Escherichia coli, Humans, Pseudomonas Infections, Pyocins/pharmacology, Soluble pyocins, Receptor binding domain

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37819519
https://hal.science/hal-04313709v1
https://doi.org/10.1007/978-1-0716-3473-8_9
https://biblio.vub.ac.be/vubir/pseudomonas-aeruginosa-soluble-pyocins-as-antibacterial-weapons(c2171178-55a4-4fc7-9ee1-733eafaefe9b).html

Identification and distribution of new candidate T6SS effectors encoded in Salmonella Pathogenicity Island 6

Autoren: Carlos J. Blondel Fernando A. Amaya Paloma Bustamante et al.

Quelle: Front Microbiol
Frontiers in Microbiology, Vol 14 (2023)

Schlagwörter: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, T6SS, effector, Salmonella, SPI-6, immunity protein, Microbiology, QR1-502

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37664116
https://doaj.org/article/8ac4edc023264d278579ef576406a238

The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58

Autoren: Tan, Kemin Johnson, Parker M Stols, Lucy et al.

Quelle: Acta Crystallographica Section F: Structural Biology Communications. 71(6)

Schlagwörter: Biochemistry and Cell Biology, Biological Sciences, Infectious Diseases, Genetics, Prevention, 2.2 Factors relating to the physical environment, 1.1 Normal biological development and functioning, Infection, Amino Acid Motifs, Animals, Antibiosis, Bacterial Toxins, Contact Inhibition, Crystallography, X-Ray, Endoribonucleases, Escherichia coli, Escherichia coli Proteins, Gene Expression, Molecular Docking Simulation, Molecular Sequence Data, Neisseria meningitidis, Protein Binding, Protein Structure, Secondary, Protein Structure, Tertiary, Recombinant Proteins, Sequence Alignment, Structural Homology, Protein, Xenopus Proteins, Xenopus laevis, contact-dependent growth inhibition, CdiA-CT toxin domain, CdiI immunity protein, toxin-immunity protein complex, docking studies, toxin–immunity protein complex

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/19d52346
https://escholarship.org/content/qt19d52346/qt19d52346.pdf

A Clickable Photosystem I, Ferredoxin, and Ferredoxin NADP+ Reductase Fusion System for Light-Driven NADPH Regeneration**

Autoren: Medipally, Hitesh Mann, Marvin Kötting, Carsten et al.

Quelle: ChemBioChem 24 (2023) 14 ; ISSN: 1439-4227

Schlagwörter: NADP photoreduction, NADPH, ferredoxin, ferredoxin NADP reductase, fusion protein, immunity protein 7, photosystem I

Dateibeschreibung: application/pdf

Relation: https://edepot.wur.nl/635610

Verfügbarkeit: https://research.wur.nl/en/publications/a-clickable-photosystem-i-ferredoxin-and-ferredoxin-nadpsupsup-re
https://doi.org/10.1002/cbic.202300025
https://edepot.wur.nl/635610

A Novel Deoxyribonuclease Low-Molecular-Weight Bacteriocin, Carocin S4, from Pectobacterium carotovorum subsp . carotovorum

Autoren: Huang-Pin Wu Reymund C. Derilo Shih-Hao Hsu et al.

Quelle: Microorganisms, Vol 11, Iss 7, p 1854 (2023)

Schlagwörter: Pectobacterium carovotorum subsp . carotovorum, bacteriocin, Carocin, killer protein, immunity protein, low-molecular-weight bacteriocin, Biology (General), QH301-705.5

Relation: https://www.mdpi.com/2076-2607/11/7/1854; https://doaj.org/toc/2076-2607; https://doaj.org/article/9e13c2877f0d4a9cb13636f26f4e5199

Verfügbarkeit: https://doi.org/10.3390/microorganisms11071854
https://doaj.org/article/9e13c2877f0d4a9cb13636f26f4e5199

Distinct immunity protein families mediate compartment-specific neutralization of a bacterial toxin.

Autoren: Alcock, Felicity Yang, Yaping Deme, Justin et al.

Quelle: Cell Rep ; ISSN:2211-1247 ; Volume:44 ; Issue:11

Schlagwörter: CP: Microbiology, Staphylococcus aureus, bacterial antagonism, immunity protein, protein secretion, protein toxin, type VII secretion system

Relation: https://doi.org/10.1016/j.celrep.2025.116459; https://pubmed.ncbi.nlm.nih.gov/41129315

Verfügbarkeit: https://doi.org/10.1016/j.celrep.2025.116459
https://pubmed.ncbi.nlm.nih.gov/41129315

Cpe1 tox targets and cleaves the type II DNA topoisomerases GyrB and ParE.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Relation: https://figshare.com/articles/figure/Cpe1_sub_tox_sub_targets_and_cleaves_the_type_II_DNA_topoisomerases_GyrB_and_ParE_/29160725

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.g003
https://figshare.com/articles/figure/Cpe1_sub_tox_sub_targets_and_cleaves_the_type_II_DNA_topoisomerases_GyrB_and_ParE_/29160725

Cpi1 employs a competitive inhibitory mechanism to neutralize Cpe1.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Relation: https://figshare.com/articles/figure/Cpi1_employs_a_competitive_inhibitory_mechanism_to_neutralize_Cpe1_/29160731

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.g005
https://figshare.com/articles/figure/Cpi1_employs_a_competitive_inhibitory_mechanism_to_neutralize_Cpe1_/29160731

The original tree file for generating the phylogenetic trees in Figs 1D and S2.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Relation: https://figshare.com/articles/dataset/The_original_tree_file_for_generating_the_phylogenetic_trees_in_Figs_1D_and_S2_/29160710

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.s020
https://figshare.com/articles/dataset/The_original_tree_file_for_generating_the_phylogenetic_trees_in_Figs_1D_and_S2_/29160710

Cpe1 tox -mediated intoxication disrupts topoisomerase activity, thereby altering DNA topology and impairing DNA replication and chromosome segregation.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.g004
https://figshare.com/articles/figure/Cpe1_sub_tox_sub_-mediated_intoxication_disrupts_topoisomerase_activity_thereby_altering_DNA_topology_and_impairing_DNA_replication_and_chromosome_segregation_/29160728

Cpe1 tox -Cpi1 is a functional effector-immunity pair.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.g002
https://figshare.com/articles/figure/Cpe1_sub_tox_sub_-Cpi1_is_a_functional_effector-immunity_pair_/29160722

PLCP toxins are found in distinct gram-negative species and are associated with interbacterial toxin delivery pathways.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.g001
https://figshare.com/articles/figure/PLCP_toxins_are_found_in_distinct_gram-negative_species_and_are_associated_with_interbacterial_toxin_delivery_pathways_/29160716

Raw data for figures containing numerical data.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Relation: https://figshare.com/articles/dataset/Raw_data_for_figures_containing_numerical_data_/29160707

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.s019
https://figshare.com/articles/dataset/Raw_data_for_figures_containing_numerical_data_/29160707

Time-lapse phase contrast microscopy series of E. coli expressing Cpe1 tox C362A . Related to Fig 2.

Autoren: Pin-Yi Song Chia-En Tsai Yung-Chih Chen et al.

Schlagwörter: Biophysics, Biochemistry, Microbiology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, previously characterized effector, impaired bacterial growth, exhibit proteolytic activity, escherichia coli <, dependent growth inhibition, active site occlusion, toxin delivery pathways, intoxication remains unresolved, immunity protein reveals, disrupts dna replication, div >< p, interbacterial toxin predicted, pare , interbacterial intoxication, protease toxin, supercoiled dna, immunity pairs, unique mode, toxic effectors, provide insights, profoundly influencing, previous studies, precise mechanism, negative bacteria

Verfügbarkeit: https://doi.org/10.1371/journal.pbio.3003208.s013
https://figshare.com/articles/media/Time-lapse_phase_contrast_microscopy_series_of_i_E_coli_i_expressing_Cpe1_sub_tox_sub_sup_C362A_sup_Related_to_Fig_2_/29160689