Suchergebnisse - "Immune Reprogramming"

Reprogramming immunity: Emerging therapeutic frontiers and clinical trial advances of CAR-T cell therapy in autoimmune diseases

Autoren: Arpita Mukherjee

Quelle: Clinical Immunology Communications, Vol 8, Iss , Pp 60-74 (2025)

Schlagwörter: CAR-T cell therapy, Autoimmune diseases, Immune reprogramming, Immune tolerance, CD19, Tregs, Immunologic diseases. Allergy, RC581-607

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772613425000150; https://doaj.org/toc/2772-6134

Zugangs-URL: https://doaj.org/article/51db8a1a4262453687a5eee1a14ee315

Single-atom Ca nanozyme induces glioma death through Ca2+-overload-enhanced catalytic tumor nanotherapy, ferroptosis and synergistic remodeling of the immune microenvironment

Autoren: Zhizhong Jin Xinqiao Li Xiaoyu Hou et al.

Quelle: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-19 (2025)

Schlagwörter: Single-atom nanozyme, Glioblastoma therapy, Ferroptosis, Pyroptosis, Immune reprogramming, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1477-3155

Zugangs-URL: https://doaj.org/article/607fb6610aba44918f9a21a259582c59

Design and construction of nanoengineered multifunctional microneedles with sustained-release properties for targeted microenvironment remodeling in diabetic bone regeneration

Autoren: Heyi Gong Sihan Ma Boyuan Wang et al.

Quelle: Materials Today Bio, Vol 35, Iss , Pp 102494- (2025)

Schlagwörter: Microneedles, Controlled release, Nanoparticles, Diabetic bone regeneration, Immune reprogramming, Drug delivery, Medicine (General), R5-920, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006425010658; https://doaj.org/toc/2590-0064

Zugangs-URL: https://doaj.org/article/9ed5d32079744cd8861a17597deb6108

Immune Reprogramming Of Photothermal Engineered Arginine Bacteria In Stomatology Disease

Autoren: Rourong Chen Yang Hongyu Guojun Huang et al.

Quelle: International Dental Journal, Vol 75, Iss , Pp 105036- (2025)

Schlagwörter: Photothermal Therapy, Engineering Bacteria, Oral Microflora, Immune Reprogramming, Immunogenic Cell Death, Dentistry, RK1-715

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0020653925043199; https://doaj.org/toc/0020-6539

Zugangs-URL: https://doaj.org/article/a8b23d39b07642c08e7e9afd2864881a

Microneedle patches with antimicrobial and immunomodulating properties for periodontal regeneration

Autoren: Boyuan Wang Heyi Gong Yang Jiang et al.

Quelle: Materials & Design, Vol 255, Iss , Pp 114168- (2025)

Schlagwörter: Microneedles, Periodontitis, M2-exosomes, Immune Reprogramming, Bone Regenaration, Materials of engineering and construction. Mechanics of materials, TA401-492

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S026412752500588X; https://doaj.org/toc/0264-1275

Zugangs-URL: https://doaj.org/article/87b74dd746af4383b53bc6fa9273c6e6

Engineered Bacteria-Nano Hybrid System: The Intelligent Drug Factory for Next-Generation Cancer Immunotherapy

Autoren: Guisha Zi Wei Zhou Ling Zhou et al.

Quelle: Pharmaceutics, Vol 17, Iss 10, p 1349 (2025)

Schlagwörter: engineered bacteria-nano hybrid system, tumor targeting, immune reprogramming, synthetic biology, controlled release, Pharmacy and materia medica, RS1-441

Dateibeschreibung: electronic resource

Relation: https://www.mdpi.com/1999-4923/17/10/1349; https://doaj.org/toc/1999-4923

Zugangs-URL: https://doaj.org/article/32d768a4b5ce45fda3b6ddb7089e2318

GcMAF, Nagalase Suppression & Fibrin Reduction – A Quantum Oncology OS Expansion

Autoren: Mohamed, Anwar

Schlagwörter: Tumor Microenvironment/genetics, Clinical Integrative Medicine, Tumor Microenvironment/physiology, Sublingual Immunotherapy/trends, GcMAF, Immunotherapy/standards, Exosomes, Medical Oncology, Tumour Microenvironment, Immunotherapy, Adoptive, Clinical Trial Protocols as Topic, Fibrin/standards, Clinical Protocols, Molecular Chaperones/immunology, Fibrin/immunology, Tumor Microenvironment, Immune Evasion/drug effects, Vision, Monocular/immunology, PEMF, Heparin, Low-Molecular-Weight/immunology, Systems Biology, Clinical Protocols/standards, Nagalase, Redox Medicine, Immunotherapy/classification, Exosomes/immunology, Tumor Microenvironment/drug effects, Fibrin/chemistry, EZ Water, Biofield Science, Exposome, Scalar Fields, CD68 Molecule/immunology, Tumour Holography, Oncology, Quantum Oncology, Cardio-Oncology, Structured Water, Systems Biology/standards, Immunotherapy, Fibrin/pharmacokinetics, Exosomes/physiology, Kininogen, Low-Molecular-Weight/immunology, Molecular Immunology, Integrative Oncology/standards, Systems Biology/methods, Psycho-Oncology, Immunotherapy/psychology, TRPV Cation Channels, Fourth Phase Water, Fibrin/metabolism, Fibrin/physiology, Immunotherapy/ethics, ECS Therapeutics, Tumor Microenvironment/immunology, Integrative Oncology, Cancer Stealth, Systems Biology/education, Immune Evasion/immunology, Exosomes/genetics, Exosomes/classification, Bioelectric Medicine, Systems Biology/ethics, Immune Evasion, Fibrin, Immune Evasion/genetics, Sublingual Immunotherapy, Fibrin/classification, Exosomes/chemistry, Pathogen-Associated Molecular Pattern Molecules/immunology, Fibrin/agonists, Fibrin/genetics, ECS, Immune Reprogramming, Immunotherapy, Active, Systems Biology/trends, Immune Evasion/physiology, Sublingual Immunotherapy/economics, TRPV1, Immunotherapy/trends, Clinical Protocols/classification, AI in Healthcare

AI-driven immunology, quantum bioenergetics, bioelectromagnetic modulation, immunometabolism, epigenetic immunomodulation, precision immunotherapy, immune recalibration, quantum computing in biology, personalized medicine

Autoren: Mohamed, Anwar

Schlagwörter: Epigenomics, AI Immunology, Immune Cell Metabolism, RNA, Mitochondrial, CRISPR-Associated Proteins, Quantum Biology, Autoimmunity, Adaptive Immunity/immunology, Mitochondria/chemistry, Adaptive Immunity, Mitochondrial ADP, ATP Translocases/genetics, Epigenesis, Genetic, Redox Signaling, Inflammation/genetics, Immune Engineering, Systems Biology, Inflammation/metabolism, Longevity/genetics, Cytokine Storm, Histone Modification, Innate Immunity, Mitochondria, Quantum Immunology, Immune System Diseases, CRISPR, Autoimmunity/genetics, Mitochondria/pathology, Inflammation/therapy, Epigenetics, Inflammation Mediators, Epigenomics/education, Immune System/innervation, Mitochondrial ADP, ATP Translocases/immunology, Epigenetic Memory/immunology, Innate Immunity Recognition/immunology, Longevity, Innate Immunity Recognition/genetics, Bioenergetics, DNA, Mitochondrial, Immunity, Innate/immunology, Mitochondria/metabolism, Bioelectric Medicine, miRNA, Inflammation, Immunometabolism, Immune Reprogramming, Systems Biology/trends, Frequency Medicine, Innate Immunity Recognition, Immunity, Innate, ATP, Longevity/immunology, Adaptive Immunity/genetics, Immune system, Immune Aging, Immune System, Mitochondria/genetics, Immunity, Innate/genetics, Immune System/immunology, Mitochondrial ADP, ATP Translocases/metabolism, Epigenetic Memory, Epigenomics/trends, Inflammation/pathology

Lung immune incompetency after mild peritoneal sepsis and its partial restoration by type 1 interferon: a mouse model study

Autoren: Qiuming Meng Fumiko Seto Tokie Totsu et al.

Quelle: Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-14 (2024)

Schlagwörter: Sepsis, Acute lung injury, ARDS, Innate immunity, Immune suppression, Immune reprogramming, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2197-425X

Zugangs-URL: https://doaj.org/article/923c0e4bf8d245519946b6d2b8b31ef2

Lung Transplant Surgery with the ψ–Hamzah Model: A Fractal–Fractional Paradigm for Optimizing Outcomes in End-Stage Pulmonary Disease.

Autoren: JALALI, SEYED RASOUL

Schlagwörter: Lung transplantation, ψ–Hamzah model, Hamzah equation, fractional calculus, fractal dynamics, lung surgery, pulmonary fibrosis, COPD, cystic fibrosis, pulmonary hypertension, end-stage pulmonary disease, solid organ transplant, transplant immunology, graft survival, chronic lung allograft dysfunction, CLAD, acute rejection, ischemia-reperfusion injury, immunosuppression, systemic immunosuppressants, cyclosporine, tacrolimus, mycophenolate, corticosteroids, immune tolerance, regulatory T cells, dendritic cells, cytokine oscillations, immune reprogramming, immunological memory

Relation: https://zenodo.org/records/16907678; oai:zenodo.org:16907678; https://doi.org/10.5281/zenodo.16907678

Verfügbarkeit: https://doi.org/10.5281/zenodo.16907678
https://zenodo.org/records/16907678

Rewriting the Future of Autoimmune Disease Treatment: Mathematical, Numerical, and Biological Proof of Superiority of the ψ–Hamzah Model in Treating Systemic Lupus Erythematosus (SLE).

Autoren: JALALI, SEYED RASOUL

Schlagwörter: Systemic Lupus Erythematosus, SLE, ψ–Hamzah Equation, Hamzah Model, Fractional Calculus, Fractal Dynamics, Complex Integrals, Autoimmune Disease, Lupus Treatment, Immune Reprogramming, Immunological Modeling, Fractional Derivatives, Autoimmune Network, Self-Recognition Restoration, Treg Cells, Th17 Inhibition, B-cell Regulation, Autoantibody Neutralization, Anti-dsDNA, Cytokine Modulation, NF-κB Pathway, JAK/STAT Pathway, MAPK Pathway, Immune Complexes, Tissue Damage Control, Mathematical Immunology, Computational Immunology, Bioinformatics in Lupus, Quantum Immunology, Immune Memory

Relation: https://zenodo.org/records/16907662; oai:zenodo.org:16907662; https://doi.org/10.5281/zenodo.16907662

Verfügbarkeit: https://doi.org/10.5281/zenodo.16907662
https://zenodo.org/records/16907662

Quantum Nanovaccine ψ–Hamzah.

Autoren: JALALI, SEYED RASOUL

Schlagwörter: Quantum Nanovaccine, ψ–Hamzah, Hamzah Equation, quantum immunology, nanomedicine, quantum biology, fractal immunology, immune synchronization, quantum entanglement, nanotechnology, fractal vaccine, genomic reprogramming, immune autoeducation, global immunity, planetary health, lifetime immunity, universal vaccine, pan-immunity, immune reprogramming, fractal RNA, quantum nanostructure, QDot–Hamzah, fractal modulation, genomic calibration, holographic immunity, neural–immune interface, quantum fractal modeling, nonlocal immune response, Global Immunic Resonance, nanovector

Relation: https://zenodo.org/records/16899582; oai:zenodo.org:16899582; https://doi.org/10.5281/zenodo.16899582

Verfügbarkeit: https://doi.org/10.5281/zenodo.16899582
https://zenodo.org/records/16899582

Intratumoral Bacterial-Targeted Cascade-Responsive Sonoafterglow Nanoprobes for Immune Reprogramming and Visualization in Glioblastoma

Autoren: Yanping Jiang Jiawei Zhang Jingjing Ye et al.

Schlagwörter: Biophysics, Medicine, Microbiology, Cell Biology, Pharmacology, Immunology, Cancer, Space Science, upon us activation, promote tumor progression, ablating tumor cells, tumor immune microenvironment, sup >–, promising gbm therapy, 2 , responsive sonoafterglow nanoprobes, integrating bacterial targeting, 1 , intratumoral bacterial, immune reprogramming, immune modulation, sonoafterglow pro, reprogramming macrophages, platform presents, immunosuppressive macrophages, gbm accumulation, fold enhancement, achieving real

Verfügbarkeit: https://doi.org/10.1021/acs.analchem.5c01626.s001
https://figshare.com/articles/journal_contribution/Intratumoral_Bacterial-Targeted_Cascade-Responsive_Sonoafterglow_Nanoprobes_for_Immune_Reprogramming_and_Visualization_in_Glioblastoma/29553089

Beyond Adaptive Immunity: Trained Innate Immune Responses as a Novel Frontier in Hepatocellular Carcinoma Therapy

Autoren: Ching-Hua Hsieh Pei-Chin Chuang Yueh-Wei Liu

Quelle: Cancers ; Volume 17 ; Issue 7 ; Pages: 1250

Schlagwörter: trained immunity, hepatocellular carcinoma (HCC), tumor microenvironment (TME), innate immune reprogramming, immune checkpoint inhibitors (ICIs)

Dateibeschreibung: application/pdf

Relation: Cancer Immunology and Immunotherapy; https://dx.doi.org/10.3390/cancers17071250

Verfügbarkeit: https://doi.org/10.3390/cancers17071250

Effective Treatment of Multisystem Autoimmune Diseases via the Hamzah Model.

Autoren: JALALI, SEYED RASOUL

Schlagwörter: Autoimmune diseases, multisystem autoimmunity, systemic lupus erythematosus, multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, immune reprogramming, immune recalibration, Hamzah Equation, ψ–Hamzah Model, fractal derivatives, fractional calculus, memory-dependent dynamics, nonlocal interactions, immune cognition, cognitive immunology, immunological re-education, vaccine design, nanomedicine, nanotechnology, nanoparticle vaccine, nanolipid carrier, PEGylated nanoparticles, fractal memory, fractal noise, stochastic fluctuations, nonlinear integrals, complex integrals, adaptive immune modelling, T cells

Relation: https://zenodo.org/records/16896483; oai:zenodo.org:16896483; https://doi.org/10.5281/zenodo.16896483

Verfügbarkeit: https://doi.org/10.5281/zenodo.16896483
https://zenodo.org/records/16896483

Navigating the nano-bio immune interface: advancements and challenges in CNS nanotherapeutics

Autoren: Chantalle Moulton Anna Baroni Erica Quagliarini et al.

Quelle: Front Immunol
Frontiers in Immunology, Vol 15 (2024)

Schlagwörter: Central Nervous System, 0301 basic medicine, 0303 health sciences, biomolecular corona, immune reprogramming, Immunology, nanotherapeutics, immunosurveillance, RC581-607, central nervous system, 03 medical and health sciences, Nanomedicine, Central Nervous System Diseases, Humans, Nanoparticles, Animals, nanoparticles, Immunologic diseases. Allergy, molecular rehabilitation

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39600701
https://doaj.org/article/cda00adfbfba4608bb367e763742d187
https://hdl.handle.net/10807/299656
https://doi.org/10.3389/fimmu.2024.1447567

Advanced Therapeutic Model for Type 1 Diabetes Treatment via ψ–Hamzah Model

Autoren: JALALI, SEYED RASOUL

Schlagwörter: ψ–Hamzah, Type 1 Diabetes, T1D, autoimmune disease, β-cells, insulin, glucose metabolism, autoimmune response, immune tolerance, nanovaccine, injectable drug, oral nano-drug, lipid nanoparticles, mRNA technology, fractional calculus, biological quantum field theory, mathematical modeling, immune system dynamics, immune modulation, β-cell regeneration, diabetes cure, nanomedicine, immunotherapy, immune suppression, immune activation, Treg cells, CpG, IL-10, TGF-β1, PLGA nanoparticles, immunomodulation, quantum field theory, fractional derivatives, complex integral, biosignaling, cell therapy, immune cells, therapeutic agents, molecular therapy, therapeutic nanocarriers, quantum biology, regenerative medicine, autoimmune treatment, targeted drug delivery, gene delivery, nanotechnology, PEGylation, immunological treatment, immune tolerance induction, β-cell function, diabetes management, nanostructures, immune suppression, immune activation, regenerative therapeutics, immunomodulatory therapy, β-cell survival, chronic autoimmune diseases, mRNA vaccines, nanoformulations, immune checkpoint inhibitors, synthetic biology, cellular therapy, chronic inflammation, cellular regeneration, tissue engineering, bioinformatics, systems biology, molecular biology, clinical translation, preclinical trials, regulatory guidelines, WHO, FDA, EMA, clinical trials, autoimmune suppression, immune system restoration, drug development, immune therapeutics, nanocarrier systems, T1D prevention, therapeutic vaccines, clinical efficacy, health innovation, biopharmaceuticals, diabetes research, computational models, mathematical simulations, molecular modeling, immune therapies, disease control, insulin production, autoimmunity, lipid vesicles, immune cell dynamics, autoantibodies, nanomaterials, regulatory approval, clinical research, immune memory, nanoencapsulation, quantum mechanics, regenerative therapy, cytokine modulation, cytokine therapy, immune surveillance, autoimmune modulation, immune cell trafficking, β-cell protection, chronic autoimmune conditions, nanovector vaccines, T1D pathogenesis, immune checkpoint therapy, cytokine release, therapeutic antibodies, T1D remission, immune system reset, immune system homeostasis, chronic disease therapy, β-cell autoimmunity, immune tolerance therapy, nanobiotechnology, disease remission, molecular immunology, cell signaling, experimental diabetes models, therapeutic nanoparticles, diabetes prevention, personalized medicine, autoimmune therapy, immune engineering, novel therapies, lipid-based vaccines, advanced therapeutics, clinical pharmacology, T-cell modulation, systemic diseases, pharmaceutical biotechnology, diabetes pathophysiology, personalized therapeutics, precision medicine, quantum immunology, fractional immuno-dynamics, nanoparticle drug delivery, bio-electronic energy, immune chaos, unstable immune network, regenerative β-cells, immune checkpoint therapy, immune chaos modeling, autoimmune reversal, insulin independence, immune programming, nanomedicine vaccines, nanoparticle encapsulation, immune phase oscillation, genetic reprogramming, cytokine suppression, autoimmune shut-down, T-cell reset, immune homeostasis, immune chaos stabilization, chronic illness cure, immune tolerance stability, β-islet regeneration, pancreatic stem cells, immune tolerance pathways, autoimmune suppression drug, immune reset nanomedicine, nanoparticle-based therapy, nanostructured vaccines, autoimmune eradication, diabetes reversal, nanotechnology-driven cure, biological quantum therapy, regenerative pharmacology, immune nanoengineering, nano-enabled cure, systemic autoimmune regulation, clinical nanomedicine, advanced drug delivery, non-invasive diabetes cure, bio-quantum vaccine, therapeutic nanodrug, quantum–immunological model, fractional bio-mathematics, molecular quantum medicine, experimental diabetes cure, quantum regenerative system, immune quantum dynamics, β-cell stability, fractal immunology, computational nanomedicine, nanoscience in diabetes, clinical-grade nanoformulation, immune chaos fractals, immune instability correction, β-cell immune protection, nano-biophysics, immune quantum oscillations, regenerative β-cell therapy, nanotechnology in T1D, systemic autoimmune correction, T1D cure simulation, next-generation nanomedicine, nano-enabled autoimmune therapy, immune chaos suppression, immune modulation nanoparticles, bio-nano therapy, β-cell quantum regeneration, nano-based drug development, autoimmune control, immune resilience therapy, immune chaos eradication, systemic bio-reprogramming, nano-immune reprogramming, biofield modulation, immuno-fractal modeling, quantum–fractional dynamics, autoimmune reversal model, insulin-free treatment, immune chaos cure, nanotechnology-based immunotherapy, clinical quantum pharmacology, advanced immune engineering, autoimmune vaccine therapy, nanomedicine revolution, systemic cure for T1D, fractal-based therapy, β-cell rejuvenation, permanent diabetes cure, immune reprogramming nanoparticles, T-cell immune tolerance, immune quantum regulation, autoimmunity cure, regenerative immunology, nanomedicine approach, ψ-field therapy, quantum-driven cure, diabetes-free future, autoimmune eradication nanomedicine, clinical trial nanotherapy, immune nanomodulation, β-cell cure system, next-gen diabetes treatment, autoimmune chaos management, T1D definitive cure

Multiple Sclerosis Treatment via the ψ–Hamzah Model: A Quantum–Mathematical Framework for Complete Myelin Regeneration and Immune Reprogramming

Autoren: JALALI, SEYED RASOUL

Schlagwörter: ψ–Hamzah Model, Multiple Sclerosis treatment, MS cure, neuroinflammation resolution, fractional calculus, fractional derivatives, fractal geometry, memory-based mathematics, immune-neural dynamics, quantum biology, quantum field interactions, physiological memory, nonlinear immune feedback, fractal neurotissue, demyelination reversal, myelin sheath regeneration, oligodendrocyte precursor activation, neuroimmune system modeling, fractional-order differential equations, Caputo fractional derivative, Grünwald–Letnikov method, fractal integral calculus, immune memory modeling, time-delayed immune response, CNS immune regulation, relapsing–remitting MS, progressive MS, neurodegeneration modeling, remyelination therapy, myelin repair algorithms, astrocyte–microglia dynamics, fractal neurogeometry, immune tolerance induction, ψ–Hamzah Nanovaccine, Hamzah-MSx vaccine, nanomedicine for MS, biodegradable nanoparticles, PLGA nanoparticles, PEG-PLA conjugation, IL-10 lipid core, antioxidant nanotherapy, Mannose-targeted dendritic cell delivery, AMMP-21 peptide mimic, immune system retraining, Treg induction, Th17 inhibition, IFN-γ suppression, CD8+ tolerance induction, long-term remission, zero-toxicity nanomedicine, neuroprotective drug design, Hamzah-MRx oral drug, dual nanocapsulation, PEGylated nanoparticles, blood-brain barrier penetration, smart drug formulations, CurQ-ψ nanocurcumin, Bacopa Monnieri extract, Boswellia Serrata AKBA, N-acetylcysteine NAC, α-Lipoic Acid, Vitamin D3, resveratrol, pyrroloquinoline quinone PQQ, high-dose biotin therapy, L-Theanine CNS relaxation, nanotechnology-based oral drugs, synaptic regeneration, mitochondrial protection, immune suppression modeling, cytokine inhibition, IL-6 pathway suppression, TNF-α inhibition, NF-κB pathway regulation, CNS oxidative stress control, neurotrophic factor activation, neuroplasticity enhancement, fractional neuroimmunology, immune–myelin fractal modeling, ψ–Hamzah computational simulations, immune feedback integrals, Python-coded immune modeling, advanced RK4 solutions, Runge-Kutta fractional simulations, bioinformatics-driven immunotherapy, quantum neuroscience, integrative neuroimmunology, mathematical immunotherapy, brain-immune computational interface, neuroregeneration through fractals, personalized neurotherapy, computational immunology, AI-driven immunotherapy, multi-agent immune modeling, multi-scale neuroimmune analysis, fractional feedback loops, hysteretic neuronal response, stochastic immune modeling, immune chaos theory, nonlinear differential immune equations, simulation-based neurotherapy, computational medicine, biofield dynamics, electromagnetic field therapy, quantum resonance therapy, mind-body synchronization, neurofeedback therapy, biofeedback therapy, meditation in MS, consciousness-based healing, energy-based therapy, field manipulation, electromagnetic modulation of immune cells, neuroimmune resonance, quantum coherence in neuroregeneration, fractal immune response, integral memory immune repair, self-healing mathematical models, WHO recommendations MS, FDA breakthrough designation, EMA approval MS therapy, NIH neurodegenerative grants, Horizon Europe funding neuroimmunology, international ψ–Hamzah consortium, autoimmune disease resolution, neurodegenerative cure framework, universal ψ–Hamzah vaccine concept, Hamzah Equation intellectual property, Seyed Rasoul Jalali innovation, fractal neurobiology, mathematical cure for autoimmune diseases, computational neurotherapeutics, myelin–immune integrative therapy, long-term neuroinflammation control, synaptic repair algorithms, advanced nanomedicine stability, vaccine side effect elimination, oral drug side effect elimination, neurotoxicity-free therapy, clinical trial recommendations MS, ≥99.99% treatment efficacy, CNS inflammation eradication, autoimmunity eradication, neuroimmune stability, neuron–glial interaction models, fractional–fractal neurocomputing, computational neural integrity restoration, bioresonance therapy MS, long-range neural connectivity, feedback-driven immune regulation, auto-myelin mimicry peptides, advanced nanoformulation, smart-release nanocapsules, BBB-targeted nano-delivery, immune regulatory cascades, T-cell tolerance programming, B-cell suppression, neuroimmune coding, cytokine storm prevention, long-term immune stabilization, fractal mathematics in medicine, integrative quantum immunology, systemic immune reprogramming, regenerative immunotherapy, advanced computational biomedicine, predictive immune modeling, quantum-informed drug design, fractional-order neurology, artificial intelligence in MS, deep learning for immunotherapy, machine learning for neurodegeneration, AI-assisted fractional modeling, predictive neural resilience, multiscale CNS healing, precision computational therapy, holistic MS treatment, quantum-informed personalized medicine, neuroimmune computational intelligence, mathematics-driven neuroimmunity, cross-disciplinary neurotherapeutics, regenerative bioinformatics, computational neurology paradigms, immune fractal topology, CNS regenerative modeling, nonlinear neuroimmune maps, myelin preservation algorithms, remyelination success modeling, integrated vaccine–drug simulations, immune fractal synchrony, time-memory-based neurotherapy, neuroimmune chaos stabilization, demyelinating disorder eradication, CNS immune healing, autoimmune disease mathematical solution, fractal cure methodology, side-effect-free therapeutic systems, neuroimmune continuum modeling, immune fractal reprogramming, CNS immune balance restoration, personalized computational cure, WHO–FDA clinical mandate, ψ–Hamzah neuroimmunology revolution

Pancreatic Cancer Stage IV Surgery via the ψ–Hamzah Model: A Fractional–Fractal Therapeutic Framework for Terminal Oncology

Autoren: JALALI, SEYED RASOUL

Schlagwörter: Pancreatic cancer, stage IV pancreatic cancer, metastatic pancreatic cancer, ψ–Hamzah model, Hamzah equation, fractional calculus, fractal dynamics, complex integrals, computational oncology, tumor growth modeling, metastasis modeling, cancer kinetics, memory-dependent tumor growth, stochastic tumor modeling, angiogenesis, fractal angiogenesis, tumor vascularization, immune evasion, cancer immunology, tumor microenvironment, pancreatic adenocarcinoma, gemcitabine, FOLFIRINOX, palliative surgery, surgical oncology, terminal cancer, oncology revolution, cancer survival, pancreatic surgery, Whipple procedure, distal pancreatectomy, total pancreatectomy, unresectable cancer, surgical resectability, mathematical oncology, chaos theory in cancer, tumor progression modeling, stochastic cancer growth, immune memory in cancer, immunological reprogramming, cancer recurrence prevention, ψ–Hamzah Onco-Surgery, optimized surgical margins, fractal tumor modeling, vascular adaptation, immune reprogramming, Hamzah–NanoOnco protocol, nanoparticle therapy, fractal nanoparticles, targeted chemotherapy, local drug delivery, systemic toxicity reduction, nanomedicine, drug encapsulation, PEGylated nanoparticles, lipid nanoparticles, PLGA nanoparticles, dendritic cell modulation, T cell reprogramming, OncoVax–ψ, immunological nanovaccine, immune tolerance reset, checkpoint inhibition, PD-1 inhibition, CTLA-4 inhibition, CAR-T enhancement, NK cell activation, dendritic vaccine, tumor-associated antigens, cancer peptides, CpG ODN adjuvant, IL-2 modulation, IFN-γ activation, TNF-alpha regulation, immune checkpoint modulation, adaptive immunity, innate immunity, cancer stem cells, tumor heterogeneity, metastasis to liver, metastasis to peritoneum, metastasis to lungs, multi-organ metastasis, systemic cancer therapy, pharmacokinetics in oncology, pharmacodynamics, ADME in cancer, absorption modeling, drug distribution, drug metabolism, drug elimination, computational simulations in oncology, Runge–Kutta solver, Grünwald–Letnikov algorithm, fractional tumor equations, numerical cancer models, digital twin oncology, patient-specific simulations, personalized oncology, precision cancer medicine, predictive algorithms, clinical decision support, intraoperative guidance, postoperative cancer care, tumor recurrence modeling, cancer relapse prevention, cancer survival extension, computational immunology, immune checkpoint modeling, immune oscillations, non-linear cancer dynamics, chaos oncology, oncological bioinformatics, cancer drug design, cancer vaccine design, synthetic biology in oncology, nanoparticle manufacturing, GMP standards, clinical-grade nanoparticles, ISO standards, sterility testing, pyrogen testing, quality control, mass spectrometry in oncology, HPLC analysis, TEM imaging, nanoparticle stability, zeta potential, particle size distribution, bioreactor protocols, cleanroom synthesis, lyophilization, freeze-drying, global oncology policy, WHO cancer guidelines, FDA oncology approval, EMA oncology regulation, phase I oncology trials, phase II oncology trials, phase III oncology trials, multicenter cancer studies, translational oncology, next-generation cancer therapy, systemic resilience in oncology, regenerative oncology, oxidative stress reduction, mitochondrial regulation, DNA repair in cancer, histone reprogramming, epigenetic cancer therapy, tumor metabolism, Warburg effect, glycolysis modulation, oxidative phosphorylation modulation, cancer nanoscience, quantum biology in oncology, quantum immunology, universal cancer therapy, scientific revolution in oncology, mathematical-biological integration, advanced biomedical engineering, future of oncology, humanitarian oncology, paradigm shift in cancer care, terminal cancer reversal, survival rate extension, global fight against cancer, Seyed Rasoul Jalali, intellectual property ψ–Hamzah, oncology revolution, curative intent in stage IV cancer, transformative oncology, definitive cancer cure framework

Marburg Virus Treatment via ψ–Hamzah Model

Autoren: JALALI, SEYED RASOUL

Schlagwörter: Marburg Virus, ψ–Hamzah Model, viral hemorrhagic fever, fractional calculus, fractal dynamics, complex integral modeling, immune system oscillations, biological memory, Caputo derivative, Grünwald–Letnikov derivative, fractal geometry, non-linear dynamics, stochastic immune delay, cytokine modeling, TNF-α, IL-6, IFN-γ, viral load suppression, nanovaccine, peptide antigen, GP1,2 glycoprotein, nanoparticle delivery, PLGA nanoparticles, DMPC lipid, PEGylation, MPL-A adjuvant, ψ–Hamzah–IL33, dendritic cell activation, T-cell memory, B-cell memory, adaptive immunity, innate immunity, vaccine design, vaccine formulation, nanoparticle stabilization, epigenetic immunotherapy, RNA polymerase inhibitor, viral protease inhibitor, Hamzah–Fractal–P13, RiboStop analog, HDACi hybrid, brain penetration, blood-brain barrier crossing, Tween-80 coating, solid lipid nanoparticles, NLC, intravenous injection, viral clearance, systemic inflammation, hemorrhagic shock, fractal viral penetration, spleen viral load, brain viral dynamics, organ-specific viral modeling, nonlinear immune response, epidemic modeling, outbreak control, host-pathogen interaction, immune suppression, viral resistance, immunogenomics, mathematical biology, systems biology, computational immunology, bioinformatics, numerical simulation, Runge-Kutta, Adams–Bashforth–Moulton, predictor-corrector, Mittag-Leffler kernel, stochastic noise modeling, nonlinear oscillations, immune resilience, viral viremia phases, biphasic infection peaks, immune collapse, cellular apoptosis, NF-κB response, fractal diffusion, Koch fractal geometry, Sierpinski viral pattern, host immune delay, pandemic preparedness, epidemic response, therapeutic nanomedicine, regenerative virology, in silico modeling, vaccine efficacy, drug efficacy, 99.99% effectiveness, zero side effects, immunological stability, GMP vaccine manufacturing, GLP compliance, nanoparticle filtration, sterile processing, bioreactor conditions, NanoBR-GMPv2, LNP-mixer bioreactor, endotoxin testing, dynamic light scattering, stability testing, immunogenicity testing, preclinical trials, BSL-4 safety, FDA phase approval, EMA vaccine review, WHO recommendations, CEPI global access, GAVI distribution, emergency vaccine funding, global biotherapeutics, pandemic defense, biosecurity, antiviral strategies, therapeutic vaccines, immunotherapy, peptide-based vaccines, protein fragment vaccines, epitope-based vaccines, nanomedicine strategies, targeted delivery, immune enhancement, viral eradication, outbreak suppression, epidemic prevention, viral dynamics, pathophysiology, virology, filovirus, Ebola-related viruses, zoonotic spillover, fruit bat vector, Rousettus aegyptiacus, Ghana outbreak 2023, Uganda outbreak 2022, viral replication suppression, host immune stimulation, cell-mediated immunity, therapeutic modeling, disease containment, viral eradication strategies, antiviral drug development, nanotechnology in virology, immune checkpoint modulation, epigenetic immune reprogramming, long-term immune protection, clinical pharmacology, pharmacokinetics, pharmacodynamics, computational simulations, human simulation model, fractional-fractal bioengineering, bio-mathematical therapeutics, global health innovation, pandemic virology, epidemic biocontrol, therapeutic revolution