Suchergebnisse - "INTERLEUKINS"

Pro-Inflammatory and Anti-Inflammatory Interleukins in Periodontitis: Molecular Roles, Immune Crosstalk, and Therapeutic Perspectives.

Autoren: Martínez-García M Hernández-Lemus E

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 16; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Periodontitis*/immunology , Periodontitis*/metabolism , Periodontitis*/therapy , Periodontitis*/drug therapy , Interleukins*/metabolism , Interleukins*/immunology, Humans ; Animals ; Anti-Inflammatory Agents/therapeutic use ; Inflammation/immunology ; Inflammation/metabolism ; Biomarkers/metabolism

METTL14 Regulates the Expression of Genes Related to Interferon, Interleukin and MHC Class I in Nasopharyngeal Carcinoma Cells.

Autoren: Zhou Z Wang J Shen L et al.

Quelle: Cancer medicine [Cancer Med] 2025 Dec; Vol. 14 (23), pp. e71371.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

MeSH-Schlagworte: Nasopharyngeal Carcinoma*/genetics , Nasopharyngeal Carcinoma*/metabolism , Nasopharyngeal Carcinoma*/pathology , Gene Expression Regulation, Neoplastic* , Methyltransferases*/genetics , Methyltransferases*/metabolism , Nasopharyngeal Neoplasms*/genetics , Nasopharyngeal Neoplasms*/metabolism , Nasopharyngeal Neoplasms*/pathology , Interferons*/genetics , Interferons*/metabolism , Interleukins*/genetics , Interleukins*/metabolism , Genes, MHC Class I* , Histocompatibility Antigens Class I*/genetics, Humans ; Cell Line, Tumor

Interleukin in Immune-Mediated Diseases: An Updated Review.

Autoren: Zaroon Aslam S Hafsa et al.

Quelle: Molecular biotechnology [Mol Biotechnol] 2025 Dec; Vol. 67 (12), pp. 4403-4417. Date of Electronic Publication: 2024 Dec 23.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 9423533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0305 (Electronic) Linking ISSN: 10736085 NLM ISO Abbreviation: Mol Biotechnol Subsets: MEDLINE

MeSH-Schlagworte: Interleukins*/immunology , Interleukins*/metabolism , Autoimmune Diseases*/immunology , Immune System Diseases*/immunology, Humans ; Animals ; Lupus Erythematosus, Systemic/immunology ; Inflammation/immunology

IL-27 gut immunology: Mechanisms and potential value as a biomarker and therapeutic target in intestinal diseases.

Autoren: Han Y Wang S Li C et al.

Quelle: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115755. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Intestinal Mucosa*/immunology , Interleukin-27*/immunology , Interleukin-27*/metabolism , Intestinal Diseases*/immunology , Inflammatory Bowel Diseases*/immunology , Interleukins*/immunology , Interleukins*/metabolism, Animals ; Humans ; Biomarkers/metabolism

Structural insights into IL-31 signaling inhibition by a neutralizing antibody.

Autoren: Guo T Zheng Y Fan Z et al.

Quelle: Structure (London, England : 1993) [Structure] 2025 Dec 04; Vol. 33 (12), pp. 2133-2145.e5. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

MeSH-Schlagworte: Antibodies, Neutralizing*/chemistry , Antibodies, Neutralizing*/metabolism , Antibodies, Neutralizing*/pharmacology , Antibodies, Neutralizing*/immunology , Interleukins*/chemistry , Interleukins*/metabolism , Interleukins*/immunology , Interleukins*/genetics , Interleukins*/antagonists & inhibitors , Antibodies, Monoclonal*/chemistry, Animals ; Dogs ; Signal Transduction ; Receptors, Interleukin/chemistry ; Receptors, Interleukin/metabolism ; Models, Molecular ; Crystallography, X-Ray ; Protein Binding ; Humans ; Pruritus/chemically induced ; Pruritus/drug therapy ; Phosphorylation ; STAT5 Transcription Factor/metabolism

Chained mediation of interleukins linking fluoride exposure to frailty: a cohort study of skeletal fluorosis patients in China.

Autoren: Lu Y Tao F Hu T et al.

Körperschaften: Lu Y Tao F Hu T et al.

Quelle: Environmental health : a global access science source [Environ Health] 2025 Dec 01; Vol. 24 (1), pp. 90. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101147645 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-069X (Electronic) Linking ISSN: 1476069X NLM ISO Abbreviation: Environ Health Subsets: MEDLINE

MeSH-Schlagworte: Fluorides*/urine , Fluorides*/adverse effects , Interleukins*/blood , Frailty*/epidemiology , Frailty*/chemically induced , Environmental Exposure*/adverse effects, Humans ; China/epidemiology ; Male ; Female ; Middle Aged ; Cross-Sectional Studies ; Adult ; Aged ; Cohort Studies ; Prevalence

Investigation of the Impact of Peri-Implantitis Processes on Interleukin Profiles in Peri-Implant Crevicular Fluid.

Autoren: Volchykhina K Manukhina O Ana ID et al.

Quelle: Clinical and experimental dental research [Clin Exp Dent Res] 2025 Dec; Vol. 11 (6), pp. e70252.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 101692332 Publication Model: Print Cited Medium: Internet ISSN: 2057-4347 (Electronic) Linking ISSN: 20574347 NLM ISO Abbreviation: Clin Exp Dent Res Subsets: MEDLINE

MeSH-Schlagworte: Gingival Crevicular Fluid*/chemistry , Gingival Crevicular Fluid*/immunology , Peri-Implantitis*/metabolism , Peri-Implantitis*/immunology , Interleukins*/analysis , Interleukins*/metabolism , Dental Implants*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Interleukin-10/analysis ; Adult ; Aged ; Case-Control Studies ; Periodontal Index ; Enzyme-Linked Immunosorbent Assay ; Interleukin-6/analysis ; Interleukin-6/metabolism

IL-26 from innate lymphoid cells regulates early-life gut epithelial homeostasis by shaping microbiota composition.

Autoren: Salloum Y Gros G Quintero-Castillo K et al.

Quelle: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (23), pp. 6832-6856. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

MeSH-Schlagworte: Interleukins*/genetics , Interleukins*/metabolism , Interleukins*/immunology , Homeostasis* , Gastrointestinal Microbiome* , Immunity, Innate* , Lymphocytes*/immunology , Lymphocytes*/metabolism , Intestinal Mucosa*/immunology , Intestinal Mucosa*/microbiology , Intestinal Mucosa*/metabolism, Animals ; Zebrafish/immunology ; Epithelial Cells/metabolism ; Larva/immunology ; Humans

iTr35 cells: a novel immunoregulatory subset involved in bone loss in rheumatoid arthritis and clinical implications.

Autoren: Li Y An M Yao L et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2565438. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Arthritis, Rheumatoid*/immunology , Arthritis, Rheumatoid*/complications , Arthritis, Rheumatoid*/blood , T-Lymphocytes, Regulatory*/immunology , T-Lymphocytes, Regulatory*/metabolism , Interleukins*/metabolism , Interleukins*/immunology, Humans ; Male ; Female ; Middle Aged ; Case-Control Studies ; Prospective Studies ; Bone Density/immunology ; Adult ; Biomarkers/blood ; Osteocalcin/blood ; Aged ; Lumbar Vertebrae/diagnostic imaging ; Femur Neck/diagnostic imaging

Distribution and Age-Related Changes of IL-21 Immunopositive Cells in the Thymus of Ostrich Chicks.

Autoren: Chen M Chen S Lu Z et al.

Quelle: Journal of experimental zoology. Part A, Ecological and integrative physiology [J Exp Zool A Ecol Integr Physiol] 2025 Dec; Vol. 343 (10), pp. 1121-1125. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Periodicals, Inc Country of Publication: United States NLM ID: 101710204 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2471-5646 (Electronic) Linking ISSN: 24715638 NLM ISO Abbreviation: J Exp Zool A Ecol Integr Physiol Subsets: MEDLINE

MeSH-Schlagworte: Thymus Gland*/cytology , Thymus Gland*/metabolism , Struthioniformes* , Interleukins*/metabolism , Interleukins*/genetics , Aging*/physiology, Animals ; Interleukin-21

Evaluation of One-Time Oral Oclacitinib Administration on Pruritic Behaviours After Intradermal Interleukin-31-Induced Pruritus Injections ("Reactive" Model) in Healthy Dogs: A Blinded, Randomised, Cross-Over Study.

Autoren: Leon R Starr H Banovic F

Quelle: Veterinary dermatology [Vet Dermatol] 2025 Dec; Vol. 36 (6), pp. 838-846. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: England NLM ID: 9426187 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3164 (Electronic) Linking ISSN: 09594493 NLM ISO Abbreviation: Vet Dermatol Subsets: MEDLINE

MeSH-Schlagworte: Pyrimidines*/administration & dosage , Pyrimidines*/therapeutic use , Pruritus*/drug therapy , Pruritus*/chemically induced , Pruritus*/veterinary , Dog Diseases*/drug therapy , Dog Diseases*/chemically induced , Sulfonamides*/administration & dosage , Sulfonamides*/therapeutic use , Interleukins*/administration & dosage , Interleukins*/adverse effects, Animals ; Dogs ; Cross-Over Studies ; Administration, Oral ; Male ; Female ; Injections, Intradermal/veterinary ; Disease Models, Animal

Genetic Insights Into Depression Induced by Tuberculosis via Mediating Roles of Interleukins: Evidence From Mendelian Randomization.

Autoren: Qiu X Li H Huang W et al.

Quelle: Tropical medicine & international health : TM & IH [Trop Med Int Health] 2025 Dec; Vol. 30 (12), pp. 1321-1330. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9610576 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3156 (Electronic) Linking ISSN: 13602276 NLM ISO Abbreviation: Trop Med Int Health Subsets: MEDLINE

MeSH-Schlagworte: Tuberculosis*/genetics , Tuberculosis*/complications , Depression*/genetics , Depression*/etiology , Interleukins*/genetics, Humans ; Mendelian Randomization Analysis ; Genome-Wide Association Study ; Genetic Predisposition to Disease

Increased Circulating Interleukin Concentrations in Type 2 Diabetes: A Systematic Review and Meta-Analysis.

Autoren: Cao C Yuan J Gilbert ER et al.

Quelle: Obesity reviews : an official journal of the International Association for the Study of Obesity [Obes Rev] 2025 Dec; Vol. 26 (12), pp. e13971. Date of Electronic Publication: 2025 Jun 13.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis; Review

Info zur Zeitschrift: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 100897395 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-789X (Electronic) Linking ISSN: 14677881 NLM ISO Abbreviation: Obes Rev Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus, Type 2*/blood , Interleukins*/blood , Obesity*/blood, Humans

IL-21-reprogrammed Vδ1 T cells exert killing against solid tumors which is enhanced by CAR arming for off-the-shelf immunotherapy.

Autoren: Portillo AL Mehboob M Snyder G et al.

Quelle: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2562210. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

MeSH-Schlagworte: Interleukins*/immunology , Interleukins*/metabolism , Interleukins*/genetics , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Immunotherapy, Adoptive*/methods , Receptors, Antigen, T-Cell, gamma-delta*/immunology , Receptors, Antigen, T-Cell, gamma-delta*/metabolism , Neoplasms*/immunology , Neoplasms*/therapy , Breast Neoplasms*/immunology , Breast Neoplasms*/therapy , Ovarian Neoplasms*/immunology , Ovarian Neoplasms*/therapy, Humans ; Animals ; Interleukin-21 ; Mice ; Female ; K562 Cells ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Cytotoxicity, Immunologic ; Tumor Microenvironment/immunology ; Lymphocyte Activation/immunology ; Immunotherapy/methods

Interleukin-35 regulates the differentiation of regulatory T cells through the JAK-STAT pathway and influences glutamine metabolism in ARDS.

Autoren: Peng QZ Zhang M Zhang AP et al.

Quelle: International immunology [Int Immunol] 2025 Nov 27; Vol. 37 (11), pp. 711-727.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: [Oxford University Press Country of Publication: England NLM ID: 8916182 Publication Model: Print Cited Medium: Internet ISSN: 1460-2377 (Electronic) Linking ISSN: 09538178 NLM ISO Abbreviation: Int Immunol Subsets: MEDLINE

MeSH-Schlagworte: T-Lymphocytes, Regulatory*/immunology , Glutamine*/metabolism , Interleukins*/immunology , Interleukins*/pharmacology , Respiratory Distress Syndrome*/immunology , Respiratory Distress Syndrome*/metabolism , STAT Transcription Factors*/metabolism, Animals ; Humans ; Cell Differentiation/immunology ; Cell Differentiation/drug effects ; Mice ; Signal Transduction/immunology ; Male ; Mice, Inbred C57BL ; Janus Kinases/metabolism ; A549 Cells

Intracellular IL-24 ameliorates lipid metabolic disorders in metabolic dysfunction-associated steatohepatitis by restoring the autophagy-lysosome pathway.

Autoren: Cui J Lin Z Sun M et al.

Quelle: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Nov 25; Vol. 82 (1), pp. 417. Date of Electronic Publication: 2025 Nov 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Autophagy* , Interleukins*/metabolism , Interleukins*/genetics , Lysosomes*/metabolism , Fatty Liver*/metabolism , Fatty Liver*/pathology , Lipid Metabolism Disorders*/metabolism , Lipid Metabolism Disorders*/pathology , Metabolic Diseases*/metabolism, Animals ; Humans ; Mice ; Male ; Hepatocytes/metabolism ; Mice, Inbred C57BL ; Lipid Metabolism ; Signal Transduction ; Disease Models, Animal ; Diet, High-Fat/adverse effects ; Liver/metabolism ; Liver/pathology ; TOR Serine-Threonine Kinases/metabolism ; AMP-Activated Protein Kinases/metabolism

The recombinant IL-35 and anti-Ebi3 antibody administration before implantation modulate immune regulation and fetal outcomes in an abortion-prone mouse model.

Autoren: Slawek A Kubik P Psurski M et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Nov 19; Vol. 16, pp. 1648641. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Interleukins*/administration & dosage , Interleukins*/immunology , Interleukins*/pharmacology , Embryo Implantation*/immunology , Embryo Implantation*/drug effects , Minor Histocompatibility Antigens*/immunology , Abortion, Spontaneous*/immunology, Animals ; Female ; Pregnancy ; Mice ; Disease Models, Animal ; Recombinant Proteins/administration & dosage ; T-Lymphocytes, Regulatory/immunology ; Immune Tolerance ; Receptors, Cytokine

IL-34 as a Novel Mediator Linking Vitamin D Deficiency with Osteoporosis and Knee Osteoarthritis.

Autoren: Tarabeih N Sleiman A Kalinkovich A et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 16; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Interleukins*/blood , Interleukins*/metabolism , Osteoarthritis, Knee*/blood , Osteoarthritis, Knee*/metabolism , Osteoarthritis, Knee*/etiology , Vitamin D Deficiency*/complications , Vitamin D Deficiency*/blood , Vitamin D Deficiency*/metabolism , Osteoporosis*/blood , Osteoporosis*/metabolism , Osteoporosis*/etiology , Osteoporosis*/epidemiology, Humans ; Female ; Male ; Middle Aged ; Cross-Sectional Studies ; Aged ; Adult ; Body Composition

Association of interleukins 17A and 22 levels and their common genetic polymorphisms in Guillain Barré syndrome.

Autoren: Iqbal A Mubarak B Amar A et al.

Quelle: Journal of neuroimmunology [J Neuroimmunol] 2025 Nov 15; Vol. 408, pp. 578721. Date of Electronic Publication: 2025 Aug 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 8109498 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8421 (Electronic) Linking ISSN: 01655728 NLM ISO Abbreviation: J Neuroimmunol Subsets: MEDLINE

MeSH-Schlagworte: Interleukin-17*/blood , Interleukin-17*/genetics , Interleukins*/blood , Interleukins*/genetics , Guillain-Barre Syndrome*/genetics , Guillain-Barre Syndrome*/blood , Guillain-Barre Syndrome*/diagnosis , Polymorphism, Single Nucleotide*/genetics, Humans ; Female ; Male ; Interleukin-22 ; Adult ; Middle Aged ; Genetic Predisposition to Disease/genetics

Innate Immune Evasion of Porcine Epidemic Diarrhea Virus Through miRNA-193a-5p/IL22/pBD1 Pathway in Intestinal Epithelium.

Autoren: Feng Q Chen J Zheng Y et al.

Quelle: Transboundary and emerging diseases [Transbound Emerg Dis] 2025 Nov 11; Vol. 2025, pp. 7421187. Date of Electronic Publication: 2025 Nov 11 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Verlag Country of Publication: Germany NLM ID: 101319538 Publication Model: eCollection Cited Medium: Internet ISSN: 1865-1682 (Electronic) Linking ISSN: 18651674 NLM ISO Abbreviation: Transbound Emerg Dis Subsets: MEDLINE

MeSH-Schlagworte: Porcine epidemic diarrhea virus*/immunology , Porcine epidemic diarrhea virus*/physiology , Porcine epidemic diarrhea virus*/genetics , MicroRNAs*/genetics , MicroRNAs*/metabolism , MicroRNAs*/immunology , beta-Defensins*/genetics , beta-Defensins*/metabolism , beta-Defensins*/immunology , Intestinal Mucosa*/virology , Intestinal Mucosa*/immunology , Swine Diseases*/virology , Swine Diseases*/immunology , Immune Evasion* , Interleukins*/genetics , Interleukins*/metabolism , Interleukins*/immunology , Immunity, Innate* , Coronavirus Infections*/veterinary , Coronavirus Infections*/immunology , Coronavirus Infections*/virology, Animals ; Swine ; Interleukin-22 ; Cell Line