Výsledky vyhľadávania - "INSULIN"

Cost-effectiveness of insulin icodec for the treatment of type 2 diabetes in Canada.

Autori: Garcia DA Mau G Singh S a ďalší

Zdroj: Journal of medical economics [J Med Econ] 2025 Dec; Vol. 28 (1), pp. 1476-1499. Date of Electronic Publication: 2025 Sep 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9892255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-837X (Electronic) Linking ISSN: 13696998 NLM ISO Abbreviation: J Med Econ Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetes Mellitus, Type 2*/drug therapy , Hypoglycemic Agents*/economics , Hypoglycemic Agents*/therapeutic use , Hypoglycemic Agents*/administration & dosage , Insulin, Long-Acting*/economics , Insulin, Long-Acting*/therapeutic use , Insulin, Long-Acting*/administration & dosage , Insulin*/economics , Insulin*/therapeutic use , Insulin*/administration & dosage, Humans ; Cost-Benefit Analysis ; Canada ; Female ; Quality-Adjusted Life Years ; Male ; Middle Aged ; Insulin Detemir/economics ; Insulin Detemir/therapeutic use ; Insulin Detemir/administration & dosage ; Insulin Glargine/economics ; Insulin Glargine/therapeutic use ; Insulin Glargine/administration & dosage ; Aged ; Adult

Insulin-Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes.

Autori: Gladych-Macioszek A Ozegowska K Radzicka-Mularczyk S a ďalší

Zdroj: Journal of diabetes research [J Diabetes Res] 2025 Nov 24; Vol. 2025, pp. 3330482. Date of Electronic Publication: 2025 Nov 24 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 101605237 Publication Model: eCollection Cited Medium: Internet ISSN: 2314-6753 (Electronic) NLM ISO Abbreviation: J Diabetes Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Like Growth Factor Binding Proteins*/metabolism , Pregnancy in Diabetics*/metabolism , Pregnancy in Diabetics*/blood , Somatomedins*/metabolism , Insulin-Like Growth Factor I*/metabolism , Diabetes, Gestational*/metabolism, Humans ; Pregnancy ; Female ; Insulin-Like Growth Factor II/metabolism ; Blood Glucose/metabolism ; Insulin-Like Peptides

Estimating homeostasis model assessment for insulin secretion by using multiple adaptive regression spline in healthy Taiwanese men.

Autori: Ma CH Yeh PT Yang CC a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 17; Vol. 15 (1), pp. 40179. Date of Electronic Publication: 2025 Nov 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin Secretion* , Homeostasis* , Insulin*/metabolism, Humans ; Male ; Taiwan ; Adult ; Middle Aged ; Insulin-Secreting Cells/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/epidemiology ; Insulin Resistance ; Blood Glucose

Altered BAG3-insulin colocalization is associated with impaired first phase insulin secretion in humans.

Autori: Damiani V Di Giuseppe G Gliozzo G a ďalší

Zdroj: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2025 Nov; Vol. 229, pp. 112232. Date of Electronic Publication: 2025 May 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin*/metabolism , Adaptor Proteins, Signal Transducing*/metabolism , Apoptosis Regulatory Proteins*/metabolism , Insulin-Secreting Cells*/metabolism , Diabetes Mellitus, Type 2*/metabolism , Islets of Langerhans*/metabolism, Humans ; Male ; Insulin Secretion ; Female ; Middle Aged ; Insulin Resistance ; Adult ; Glucose Clamp Technique ; Aged ; Glucose Tolerance Test ; Blood Glucose/metabolism

Metabolic Phenotype of Stage 1 and Stage 2 Type 1 Diabetes Using Modeling of β Cell Function.

Autori: Galderisi A Bonet J Ismail HM a ďalší

Zdroj: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Oct 16; Vol. 110 (11), pp. 3168-3178.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetes Mellitus, Type 1*/metabolism , Diabetes Mellitus, Type 1*/pathology , Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/physiology, Humans ; Female ; Male ; Adult ; Glucose Tolerance Test ; Insulin Resistance ; Phenotype ; Young Adult ; Adolescent ; Insulin Secretion ; Insulin/metabolism ; Blood Glucose/metabolism ; Blood Glucose/analysis ; Disease Progression ; Middle Aged ; Models, Biological

Ethnic differences in beta cell function and pancreatic fat in Black African and White European men across a spectrum of glucose tolerance.

Autori: Whelehan G Hakim O Ladwa M a ďalší

Zdroj: Diabetologia [Diabetologia] 2025 Oct; Vol. 68 (10), pp. 2290-2295. Date of Electronic Publication: 2025 Aug 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/physiology , Diabetes Mellitus, Type 2*/ethnology , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/physiopathology , Glucose Intolerance*/ethnology , Glucose Intolerance*/metabolism , Glucose Intolerance*/physiopathology , Pancreas*/metabolism, Humans ; Male ; White People ; Black People ; Middle Aged ; Adult ; Glucose Tolerance Test ; Glucose Clamp Technique ; Insulin Resistance/physiology ; Insulin/metabolism ; Blood Glucose/metabolism

Golgi-associated TRAF6 as a regulator of protein convertase FURIN for insulin receptor precursor processing.

Autori: Liu M Zhou K Sheng Y a ďalší

Zdroj: Science China. Life sciences [Sci China Life Sci] 2025 Dec; Vol. 68 (12), pp. 3617-3632. Date of Electronic Publication: 2025 Oct 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1869-1889 (Electronic) Linking ISSN: 16747305 NLM ISO Abbreviation: Sci China Life Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Furin*/metabolism , TNF Receptor-Associated Factor 6*/metabolism , TNF Receptor-Associated Factor 6*/genetics , Golgi Apparatus*/metabolism , Receptor, Insulin*/metabolism, Animals ; Humans ; Mice ; Diet, High-Fat ; Insulin Resistance ; Signal Transduction ; Insulin/metabolism ; Mice, Inbred C57BL ; Obesity/metabolism ; Proprotein Convertase 9/metabolism ; Glucose/metabolism ; HEK293 Cells ; Ubiquitination ; Male ; Cholesterol/metabolism

The effects of free fatty acid-free bovine serum albumin and palmitate on pancreatic β-cell function.

Autori: Sentjens K Pillai R Joseph JW

Zdroj: Islets [Islets] 2025 Dec; Vol. 17 (1), pp. 2479911. Date of Electronic Publication: 2025 Mar 16.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-2022 (Electronic) Linking ISSN: 19382014 NLM ISO Abbreviation: Islets Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Secreting Cells*/drug effects , Insulin-Secreting Cells*/metabolism , Serum Albumin, Bovine*/pharmacology , Fatty Acids, Nonesterified*/pharmacology , Palmitates*/pharmacology, Humans ; Insulin/metabolism ; Animals ; Insulin Secretion/drug effects ; Cattle ; Cell Line ; Cells, Cultured

Regulation of insulin expression and release in gene and cell therapy of insulin-deficient diabetes.

Autori: Xie L Lu W Yu J a ďalší

Zdroj: European journal of endocrinology [Eur J Endocrinol] 2025 Nov 26; Vol. 193 (6), pp. R57-R70.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 9423848 Publication Model: Print Cited Medium: Internet ISSN: 1479-683X (Electronic) Linking ISSN: 08044643 NLM ISO Abbreviation: Eur J Endocrinol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin*/genetics , Insulin*/metabolism , Insulin*/deficiency , Genetic Therapy*/methods , Cell- and Tissue-Based Therapy*/methods , Diabetes Mellitus*/therapy , Diabetes Mellitus*/genetics , Diabetes Mellitus*/metabolism, Humans ; Insulin-Secreting Cells/metabolism ; Animals ; Insulin Secretion/genetics

The contrasting effects of two antimalarial drugs on insulin secretion.

Autori: Lu J Xiong F Zhang Q a ďalší

Zdroj: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Nov 25; Vol. 82 (1), pp. 419. Date of Electronic Publication: 2025 Nov 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antimalarials*/pharmacology , Insulin Secretion*/drug effects , Insulin*/metabolism , Quinine*/pharmacology , Artemisinins*/pharmacology, Animals ; Mice ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Male ; Quinolines/pharmacology ; Glucose/pharmacology ; Glucose/metabolism ; Mice, Inbred C57BL ; Artemether/pharmacology ; Calcium/metabolism ; Islets of Langerhans/drug effects ; Islets of Langerhans/metabolism

Prenatal Concentrations of Perfluoroalkyl Substances and Maternal Beta Cell Function at 7 to 9 Years of Follow-Up.

Autori: Palaniyandi J Bruin JE Fisher M a ďalší

Zdroj: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Nov 18; Vol. 110 (12), pp. e4221-e4231.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fluorocarbons*/blood , Fluorocarbons*/adverse effects , Insulin-Secreting Cells*/drug effects , Insulin-Secreting Cells*/physiology , Insulin-Secreting Cells*/metabolism , Prenatal Exposure Delayed Effects*/blood , Prenatal Exposure Delayed Effects*/chemically induced , Prenatal Exposure Delayed Effects*/epidemiology , Environmental Pollutants*/blood , Maternal Exposure*/adverse effects, Humans ; Female ; Pregnancy ; Follow-Up Studies ; Adult ; Insulin Resistance ; Child ; Blood Glucose/analysis ; Biomarkers/blood ; Insulin/blood ; Pregnancy Trimester, Second/blood ; Caprylates

Tuning insulin receptor signaling using de novo-designed agonists.

Autori: Wang X Cardoso S Cai K a ďalší

Zdroj: Molecular cell [Mol Cell] 2025 Nov 06; Vol. 85 (21), pp. 4064-4081.e9. Date of Electronic Publication: 2025 Oct 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptor, Insulin*/agonists , Receptor, Insulin*/metabolism , Receptor, Insulin*/genetics , Receptor, Insulin*/chemistry , Hypoglycemic Agents*/pharmacology , Hypoglycemic Agents*/chemistry, Humans ; Animals ; Cell Proliferation/drug effects ; Signal Transduction/drug effects ; Insulin/metabolism ; Insulin/pharmacology ; Mice ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Protein Conformation ; HEK293 Cells ; Antigens, CD

Orforglipron, an oral non-peptide glucagon-like peptide-1 receptor agonist, improves markers of β-cell function and insulin sensitivity in type 2 diabetes.

Autori: Rosenstock J Robins DA Duffin KL a ďalší

Zdroj: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Nov; Vol. 27 (11), pp. 6314-6322. Date of Electronic Publication: 2025 Aug 14.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/metabolism , Insulin Resistance* , Insulin-Secreting Cells*/drug effects , Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/physiology , Glucagon-Like Peptide-1 Receptor Agonists* , Hypoglycemic Agents*/administration & dosage , Hypoglycemic Agents*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Glucagon-Like Peptides/analogs & derivatives ; Glucagon-Like Peptides/administration & dosage ; Glucagon-Like Peptides/therapeutic use ; Biomarkers/blood ; Immunoglobulin Fc Fragments/administration & dosage ; Immunoglobulin Fc Fragments/therapeutic use ; Recombinant Fusion Proteins/administration & dosage ; Recombinant Fusion Proteins/therapeutic use ; Blood Glucose/metabolism ; Blood Glucose/drug effects ; C-Peptide/blood ; Administration, Oral ; Aged ; Insulin/blood ; Double-Blind Method ; Adiponectin/blood ; Adult ; Oxadiazoles ; Fluorine Compounds

GLP-1/GIP/GCG receptor triagonist (IUB447) enhances insulin secretion via GLP-1 receptor and Gαq signalling pathway in mice.

Autori: Schreier PCF Beyerle P Boulassel S a ďalší

Zdroj: Diabetologia [Diabetologia] 2025 Nov; Vol. 68 (11), pp. 2567-2580. Date of Electronic Publication: 2025 Sep 09.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glucagon-Like Peptide-1 Receptor*/metabolism , Glucagon-Like Peptide-1 Receptor*/genetics , Insulin Secretion*/drug effects , Receptors, Gastrointestinal Hormone*/metabolism , Receptors, Gastrointestinal Hormone*/agonists , Receptors, Gastrointestinal Hormone*/genetics , Insulin*/metabolism , GTP-Binding Protein alpha Subunits, Gq-G11*/metabolism, Animals ; Mice ; Signal Transduction/drug effects ; Mice, Knockout ; Male ; TRPM Cation Channels/metabolism ; TRPM Cation Channels/genetics ; Glucagon-Like Peptide 1/metabolism ; Islets of Langerhans/metabolism ; Islets of Langerhans/drug effects ; Gastric Inhibitory Polypeptide/metabolism ; Mice, Inbred C57BL ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/drug effects

Insulin evokes release of endozepines from astrocytes of the NTS to modulate glucose metabolism in male rats.

Autori: New LE Wang N Smith HE a ďalší

Zdroj: Molecular metabolism [Mol Metab] 2025 Nov; Vol. 101, pp. 102255. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

Výrazy zo slovníka MeSH: Astrocytes*/metabolism , Astrocytes*/drug effects , Insulin*/metabolism , Insulin*/pharmacology , Glucose*/metabolism , Solitary Nucleus*/metabolism , Solitary Nucleus*/drug effects, Animals ; Male ; Rats ; Receptors, GABA-A/metabolism ; Liver/metabolism ; Insulin Resistance ; Rats, Sprague-Dawley ; Diet, High-Fat/adverse effects ; Receptor, Insulin/metabolism ; Rats, Wistar

Impact of novel amino acid substituted and acylated spexin analogues on pancreatic beta-cell function, appetite and glucose homeostasis.

Autori: Gallagher DM Khan MZI Patterson S a ďalší

Zdroj: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2025 Nov 01; Vol. 609, pp. 112657. Date of Electronic Publication: 2025 Sep 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8057 (Electronic) Linking ISSN: 03037207 NLM ISO Abbreviation: Mol Cell Endocrinol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Secreting Cells*/drug effects , Insulin-Secreting Cells*/metabolism , Homeostasis*/drug effects , Glucose*/metabolism , Appetite*/drug effects , Endorphins*/pharmacology , Endorphins*/chemistry , Amino Acids*/chemistry, Animals ; Mice ; Male ; Cell Proliferation/drug effects ; Acylation ; Insulin Secretion/drug effects ; Cell Line ; Insulin/metabolism ; Mice, Inbred C57BL

Effect of short-term intensive insulin pump therapy on serum endotrophin levels in patients with newly diagnosed type 2 diabetes.

Autori: Li Y Gui X Weng Y a ďalší

Zdroj: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Oct 08; Vol. 16, pp. 1658272. Date of Electronic Publication: 2025 Oct 08 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/diagnosis , Insulin*/administration & dosage , Insulin Infusion Systems* , Peptide Fragments*/blood , Hypoglycemic Agents*/administration & dosage, Humans ; Male ; Female ; Middle Aged ; Insulin Resistance ; Aged ; Biomarkers/blood ; Adult ; Case-Control Studies ; Blood Glucose ; Collagen Type VI

BAF60a-dependent chromatin remodeling preserves β cell function and contributes to the therapeutic benefits of GLP-1R agonists.

Autori: Qiu X Wang RR Wu QQ a ďalší

Zdroj: The Journal of clinical investigation [J Clin Invest] 2025 Oct 02; Vol. 135 (23). Date of Electronic Publication: 2025 Oct 02 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/pathology , Chromatin Assembly and Disassembly* , Glucagon-Like Peptide-1 Receptor*/metabolism , Glucagon-Like Peptide-1 Receptor*/genetics , Chromosomal Proteins, Non-Histone*/genetics , Chromosomal Proteins, Non-Histone*/metabolism, Animals ; Humans ; Mice ; Homeodomain Proteins/metabolism ; Homeodomain Proteins/genetics ; Insulin Secretion ; Male ; Mutation, Missense ; Insulin/metabolism ; Mice, Knockout

Redox compartmentalization drives functional heterogeneity of mature insulin secretory vesicles in pancreatic β-cells.

Autori: Zhuang L Zhao Y Qin Q a ďalší

Zdroj: Redox biology [Redox Biol] 2025 Oct; Vol. 86, pp. 103847. Date of Electronic Publication: 2025 Aug 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/cytology , Secretory Vesicles*/metabolism , Insulin*/metabolism, Oxidation-Reduction ; Humans ; Animals ; Insulin Secretion ; Rats ; Cell Line ; Glucose/metabolism ; Cell Compartmentation

Salacia Reticulata Extract Improves Insulin Sensitivity and Glucose Homeostasis by Activating Insulin Signaling and Glucagon-like Peptide-1 Modulation.

Autori: Jung J Park SH Cho W a ďalší

Zdroj: Journal of medicinal food [J Med Food] 2025 Oct; Vol. 28 (10), pp. 1060-1068. Date of Electronic Publication: 2025 Jun 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9812512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7600 (Electronic) Linking ISSN: 1096620X NLM ISO Abbreviation: J Med Food Subsets: MEDLINE

Výrazy zo slovníka MeSH: Insulin Resistance* , Insulin*/metabolism , Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/genetics , Plant Extracts*/administration & dosage , Glucagon-Like Peptide 1*/metabolism , Glucagon-Like Peptide 1*/blood , Glucagon-Like Peptide 1*/genetics , Salacia*/chemistry , Glucose*/metabolism, Animals ; Signal Transduction/drug effects ; Male ; Rats ; Blood Glucose/metabolism ; Homeostasis/drug effects ; Humans ; Glucose Transporter Type 4/metabolism ; Glucose Transporter Type 4/genetics ; Rats, Inbred OLETF ; Mice ; Hypoglycemic Agents/administration & dosage ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/drug effects ; Insulin Receptor Substrate Proteins/metabolism ; Insulin Receptor Substrate Proteins/genetics ; Adiponectin/blood ; Adiponectin/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Cell Line