Suchergebnisse - "IN vivo studies"

QbD-guided development of a simvastatin-loaded transethosomal gel for enhanced transdermal delivery: optimization, characterization, and in vivo antihyperlipidemic evaluation.

Autoren: Kokatanur, Umashri A. Dandagi, Panchaxari M. Patil, Sathgowda

Quelle: Drug Development & Industrial Pharmacy. Nov2025, p1-19. 19p. 8 Illustrations.

Schlagwörter: *MATHEMATICAL optimization, TRANSDERMAL medication, IN vivo studies, PHOSPHOLIPIDS, EVALUATION methodology, SKIN absorption, ANTICHOLESTEREMIC agents, STATINS (Cardiovascular agents)

In Vivo Kinetic and Kinematic Analysis of Healthy Iliotibial Band Biomechanics.

Autoren: Felipe, Jack T. Burk, Adam M. Duong, Katherine M. et al.

Quelle: Journal of Applied Biomechanics; Oct2025, Vol. 41 Issue 5, p396-401, 6p

Schlagwörter: TENDON physiology, SKELETAL muscle physiology, HIP joint physiology, BIOMECHANICS, DIAGNOSTIC imaging, TASK performance, DATA analysis, DYNAMICS, KINEMATICS, ACCELEROMETERS, EXERCISE therapy, SEX distribution, ULTRASONIC imaging, IN vivo studies, DESCRIPTIVE statistics, GAIT in humans, MANN Whitney U Test, KNEE joint, RESISTANCE training, THIGH, TREADMILLS, ONE-way analysis of variance, STATISTICS, DATA analysis software, BODY movement, POSTURE, COMPARATIVE studies, WALKING speed, RANGE of motion of joints, MOTION capture (Human mechanics)

Health-related effects of byproducts from the food industry within in vivo models: a systematic review.

Autoren: Woelffel Silva, Caroline Dugan, Eliot M. Gracey, Peter R. et al.

Quelle: Critical Reviews in Food Science & Nutrition. 2025, Vol. 65 Issue 33, p8757-8769. 13p.

Schlagwörter: *FOOD industry, *IN vivo studies, *WELL-being, *REACTIVE oxygen species, *NUTRITIONAL value, *WASTE products

Pharmacokinetic considerations and strategies for antibody-based therapeutics.

Autoren: Zhang, Juanhong Chang, Rong Zhao, Anpeng et al.

Quelle: Drug Metabolism Reviews. Nov2025, p1-32. 32p. 10 Illustrations.

Schlagwörter: *PHARMACOKINETICS, *IN vivo studies, *EXCRETION, *BIOTHERAPY, *THERAPEUTICS, *DRUG delivery systems, *TREATMENT effectiveness, *ENDOCYTOSIS

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing.

Autoren: Hanafy, Belal I. Lu, Chuan‐En Liu, Kai et al.

Quelle: Advanced Functional Materials. Nov2025, p1. 14p. 7 Illustrations.

Schlagwörter: *NANOPARTICLES, *IN vivo studies, *SIMULATION methods & models, *NANOMEDICINE, *ANIMAL experimentation, *TARGETED drug delivery, *PREDICTION models

Establishment of A Standardized Osteotomy Model for Future in Vivo Evaluation of Bone Adhesives.

Autoren: Vasic, Katarina Boeker, Kai O. Komrakova, Marina et al.

Quelle: Clinical & Translational Metabolism. 11/22/2025, Vol. 23 Issue 1, p1-13. 13p.

Schlagwörter: *OSTEOTOMY, *IN vivo studies, *FLEXURAL strength testing, *SPRAGUE Dawley rats, *TREATMENT of fractures, *BONE regeneration, *X-ray computed microtomography, *BONE cements

Sustainable Shrimp Feeding: Digestibility of Defatted Hermetia illucens Meal by In Vitro and In Vivo Methods.

Autoren: Dornic, Aurélien Pham, Dominique Wabete, Nelly et al.

Quelle: Aquaculture Nutrition. 11/23/2025, Vol. 2025, p1-12. 12p.

Schlagwörter: *IN vitro studies, *IN vivo studies, *DIGESTION, *INSECT food, *PLANT proteins, *SUSTAINABLE aquaculture, *FISH meal

Optical Attenuation‐Resistant Photoacoustic Tomography with Isotropic Contrast via Polarization‐Demodulated Magnetic Orientation Awareness.

Autoren: Su, Xiaoye Zhang, Zhenhui Wang, Yikai et al.

Quelle: Laser & Photonics Reviews. 11/19/2025, Vol. 19 Issue 22, p1-15. 15p.

Schlagwörter: *ATTENUATION of light, *IN vivo studies, *PHOTOACOUSTIC spectroscopy, *OPTICAL images, *CONTRAST media, *BREWSTER'S angle, *MEDICAL sciences, *LINEAR polarization

iGlucoSnFR2: A genetically encoded fluorescent sensor for measuring intracellular or extracellular glucose in vivo in mouse brain.

Autoren: Marvin, Jonathan S. Mächler, Philipp Chengbo Meng et al.

Quelle: Science Advances. 11/14/2025, Vol. 11 Issue 46, p1-16. 16p.

Schlagwörter: *GLUCOSE, *IN vivo studies, *FLUOROPHORES, *CELLULAR mechanics, *DETECTORS, *RODENTS, *GAGING, *TRANSGENIC organisms

An ADAR2-mimic base editor for efficient C-to-U RNA editing in vivo.

Autoren: Chenhui Hao Niubing Zhang Ouyang Mo et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America. 11/11/2025, Vol. 122 Issue 45, p1-22. 34p.

Schlagwörter: *RNA editing, *IN vivo studies, *GENOME editing, *GENETIC mutation, *GENETIC disorders

AIEgens for in vitro and in vivo pathogen visualization.

Autoren: Xie, Xiaohan Zhao, Yanan Liu, Xingqi et al.

Quelle: Chemical Communications. 11/11/2025, Vol. 61 Issue 87, p16889-16904. 16p.

Schlagwörter: *FLUORESCENCE, *IN vivo studies, *DIAGNOSTIC imaging, *IN vitro studies, *DIAGNOSTIC services, *COMMUNICABLE diseases, *FLUORESCENT probes, *IDENTIFICATION of pathogenic microorganisms

Recent Advances in Micro/Nanoneedle Arrays Mediated Intracellular Delivery of Biomacromolecules In Vitro and In Vivo.

Autoren: Sun, Ying Miao, Dongyang Zeng, Ziyuan et al.

Quelle: Advanced Functional Materials. 11/5/2025, Vol. 35 Issue 45, p1-31. 31p.

Schlagwörter: *BIOMACROMOLECULES, *IN vivo studies, *DRUG delivery systems, *IN vitro studies, *TRANSCYTOSIS, *CELLULAR therapy, *GENOME editing, *REGENERATIVE medicine

Unveiling antidiabetic mechanisms of Raphanus sativus L. leaves: a multidimensional approach combining in vitro, in vivo, and in silico studies.

Autoren: Saha, Sakshar Paul, Shubham Chatterjee, Atanu et al.

Quelle: European Food Research & Technology. Nov2025, Vol. 251 Issue 11, p3755-3778. 24p.

Schlagwörter: *HYPOGLYCEMIC agents, *IN vivo studies, *COMPUTER simulation, *RADISHES, *IN vitro studies, *GLUCOSE-regulated proteins, *OXIDATIVE stress

Navigating complexity in modern toxicology: the role of omics in short-term in vivo studies Open Access.

Autoren: Mitchell, Constance A Wehmas, Leah Rouquié, David et al.

Quelle: Toxicological Sciences. Nov2025, Vol. 208 Issue 1, p32-37. 6p.

Schlagwörter: *TOXICOLOGY, *IN vivo studies, *BIOINFORMATICS, *RISK assessment, *ANIMAL experimentation, *STANDARDS, *MULTIOMICS

Dual-function robotic gripper for traction and closure in gastric endoscopic submucosal dissection: an in vivo porcine model study (with video).

Autoren: Kim, Sang Hyun Seo, Ye Chan Keum, Bora et al.

Quelle: Surgical Endoscopy & Other Interventional Techniques. Nov2025, Vol. 39 Issue 11, p7831-7840. 10p.

Schlagwörter: *ENDOSCOPIC gastrointestinal surgery, *IN vivo studies, *ANIMAL models in research, *MANIPULATORS (Machinery), *MECHANICAL efficiency, *HUMAN dissection, *OPERATIVE surgery

Demonstration of discriminatory power and prediction of in vivo behaviour of complex liposomal injectable formulation using physiologically based pharmacokinetic modeling.

Autoren: Boddu, Rajkumar Harika, Maddukuri Munjal, Vaneet et al.

Quelle: Journal of Liposome Research. Oct2025, p1-12. 12p. 5 Illustrations.

Schlagwörter: *PHARMACOKINETICS, *IN vivo studies, *IN vitro studies, *EXCIPIENTS, *MODEL validation, *DISSOLUTION (Chemistry), *BIOAVAILABILITY

Antistunting potential of deepsea water concentrate as multivitamin granules: stability and in vivo activity study.

Autoren: Hartesi, Barmi Retnoaji, Bambang Sriwidodo, Sriwidodo et al.

Quelle: Scientific Reports. 10/29/2025, Vol. 15 Issue 1, p1-20. 20p.

Schlagwörter: *STUNTED growth, *IN vivo studies, *CHEMICAL stability, *GRANULAR materials, *DIET therapy, *DIETARY supplements, *LABORATORY zebrafish

Immobilization of fluorescein on hemostatic starch particles for tracking degradation and distribution in vivo.

Autoren: Liu, Hao Bai, Yun Zhu, Yabin et al.

Quelle: New Journal of Chemistry. 10/14/2025, Vol. 49 Issue 38, p16654-16668. 15p.

Schlagwörter: *FLUORESCEIN, *IN vivo studies, *CHEMICAL decomposition, *BIOCOMPATIBILITY, *STARCH, *DISPERSION (Chemistry), *METABOLITES

Pig lateral femoral condyle flap is more suitable than medial femoral condyle flap for in vivo study.

Autoren: Zuo, Yanhai Liu, Junling Long, Pan et al.

Quelle: European Journal of Plastic Surgery. 10/9/2025, Vol. 48 Issue 1, p1-7. 7p.

Schlagwörter: *SWINE, *IN vivo studies, *OPERATIVE surgery, *BIOLOGICAL specimen analysis, *ANATOMY, *NEOVASCULARIZATION

Tailoring the Properties of Polydiacetylene Nanosystems for Enhanced Cell Tracking Through Poly(glycerol Adipate) Blending: an In Vitro and In Vivo Investigation.

Autoren: Brugnoli, Benedetta Axioti, Eleni Jacob, Philippa L. et al.

Quelle: Macromolecular Chemistry & Physics. Oct2025, p1. 13p. 10 Illustrations.

Schlagwörter: *INTRACELLULAR tracking, *IN vivo studies, *NANOCAPSULES, *BIOCOMPATIBILITY, *NANOPARTICLES, *NANOSCIENCE, *POLYESTERS, *IN vitro studies