Výsledky vyhľadávania - "IDIOPATHIC pulmonary fibrosis"

Integrative Analysis of Endothelial Cell Senescence-Related Genes in Idiopathic Pulmonary Fibrosis.

Autori: Chen J Wu W Ma X a ďalší

Zdroj: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Dec 15; Vol. 39 (23), pp. e71290.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/genetics , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Cellular Senescence*/genetics , Endothelial Cells*/metabolism, Humans ; Animals ; Mice ; Male ; Human Umbilical Vein Endothelial Cells/metabolism ; Female ; Transcriptome ; Bleomycin ; Mice, Inbred C57BL

2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide alleviates idiopathic pulmonary fibrosis through activation of LGALS3-mediated AGE-RAGE signaling pathway.

Autori: Chen Y Liu Q Fu R a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115635. Date of Electronic Publication: 2025 Oct 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/chemically induced , Galectin 3*/metabolism , Galectin 3*/genetics , Benzamides*/pharmacology , Benzamides*/therapeutic use , Receptor for Advanced Glycation End Products*/metabolism, Animals ; Humans ; Mice ; Signal Transduction/drug effects ; Male ; Female ; Bleomycin ; Mice, Inbred C57BL ; Disease Models, Animal ; Lung/pathology ; Lung/drug effects ; Aged ; Middle Aged ; Blood Proteins ; Galectins

Roflumilast mitigates idiopathic pulmonary fibrosis via inhibition of iron accumulation and ferroptosis.

Autori: Feng L Han S Li Y a ďalší

Zdroj: European journal of pharmacology [Eur J Pharmacol] 2025 Dec 05; Vol. 1008, pp. 178385. Date of Electronic Publication: 2025 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ferroptosis*/drug effects , Benzamides*/pharmacology , Benzamides*/therapeutic use , Aminopyridines*/pharmacology , Aminopyridines*/therapeutic use , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/chemically induced , Iron*/metabolism, Animals ; Mice ; Bleomycin ; Male ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Cyclopropanes/pharmacology ; Cyclopropanes/therapeutic use ; Lung/drug effects ; Lung/pathology ; Lung/metabolism ; Reactive Oxygen Species/metabolism ; Mice, Inbred C57BL ; Humans ; Disease Models, Animal ; Cyclic AMP Response Element-Binding Protein/metabolism

Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53.

Autori: Fan Y Tian Z Zheng H a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 03; Vol. 166, pp. 115554. Date of Electronic Publication: 2025 Sep 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tumor Suppressor Protein p53*/metabolism , Tumor Suppressor Protein p53*/genetics , Alveolar Epithelial Cells*/metabolism , Alveolar Epithelial Cells*/physiology , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/genetics , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/chemically induced , Homeodomain Proteins*/genetics , Homeodomain Proteins*/metabolism, Animals ; Cellular Senescence ; Humans ; Mice ; Bleomycin ; Mice, Inbred C57BL ; Male ; Disease Models, Animal ; Female ; Lung/pathology

Rosiridin reduces Idiopathic Pulmonary Fibrosis by inhibiting the STAT3/NFκB/SMAD3 signaling pathways.

Autori: Li Y Qi H Xu H a ďalší

Zdroj: Journal of pharmacological sciences [J Pharmacol Sci] 2025 Dec; Vol. 159 (4), pp. 242-251. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Japanese Pharmacological Society Country of Publication: Japan NLM ID: 101167001 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-8648 (Electronic) Linking ISSN: 13478613 NLM ISO Abbreviation: J Pharmacol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: STAT3 Transcription Factor*/metabolism , Signal Transduction*/drug effects , Signal Transduction*/genetics , NF-kappa B*/metabolism , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/chemically induced , Smad3 Protein*/metabolism, Animals ; Oxidative Stress/drug effects ; Bleomycin ; Humans ; Male ; Mice, Inbred C57BL ; Apoptosis/drug effects ; Transforming Growth Factor beta1

Addressing advance care planning for idiopathic pulmonary fibrosis: a call to action.

Autori: Calypso A Danoff SK Gersten RA

Zdroj: Expert review of respiratory medicine [Expert Rev Respir Med] 2025 Dec; Vol. 19 (12), pp. 1171-1179. Date of Electronic Publication: 2025 Jul 10.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101278196 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-6356 (Electronic) Linking ISSN: 17476348 NLM ISO Abbreviation: Expert Rev Respir Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/therapy , Idiopathic Pulmonary Fibrosis*/physiopathology , Idiopathic Pulmonary Fibrosis*/diagnosis , Advance Care Planning* , Terminal Care*, Humans ; Patient Preference ; Patient-Centered Care ; Disease Progression ; Prognosis

von Willebrand Factor Deficiency Inhibits Endothelial-to-Mesenchymal Transition to Attenuate Pulmonary Fibrosis.

Autori: Wang W Chen S Xi Z a ďalší

Zdroj: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2025 Dec; Vol. 73 (6), pp. 906-919.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: von Willebrand Factor*/metabolism , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/genetics , Epithelial-Mesenchymal Transition*, Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Male ; Wnt Signaling Pathway ; Lung/pathology ; Lung/metabolism ; Disease Models, Animal ; Macrophages/metabolism ; Macrophages/pathology

Development and characterization of AD-214, an anti-CXCR4 i-body-Fc fusion for the treatment of idiopathic pulmonary fibrosis.

Autori: Lynch JP Organ L Tomusange K a ďalší

Zdroj: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2505090. Date of Electronic Publication: 2025 May 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/immunology , Idiopathic Pulmonary Fibrosis*/pathology , Receptors, CXCR4*/immunology , Receptors, CXCR4*/antagonists & inhibitors , Recombinant Fusion Proteins*/pharmacology , Recombinant Fusion Proteins*/genetics , Recombinant Fusion Proteins*/immunology , Recombinant Fusion Proteins*/therapeutic use , Immunoglobulin Fc Fragments*/genetics , Immunoglobulin Fc Fragments*/immunology, Humans ; Animals ; Mice ; Cell Movement/drug effects

Microscopic polyangiitis with histopathologic evolution in serial renal biopsies during treatment of idiopathic pulmonary fibrosis.

Autori: Yamaguchi Y Tosaki T Sasaki T a ďalší

Zdroj: CEN case reports [CEN Case Rep] 2025 Dec; Vol. 14 (6), pp. 814-818. Date of Electronic Publication: 2025 Aug 13.

Spôsob vydávania: Journal Article; Case Reports

Informácie o časopise: Publisher: Springer Japan Country of Publication: Japan NLM ID: 101636244 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-4449 (Electronic) Linking ISSN: 21924449 NLM ISO Abbreviation: CEN Case Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/complications , Microscopic Polyangiitis*/pathology , Microscopic Polyangiitis*/diagnosis , Microscopic Polyangiitis*/drug therapy , Microscopic Polyangiitis*/complications , Kidney*/pathology, Humans ; Female ; Aged ; Antibodies, Antineutrophil Cytoplasmic/blood ; Biopsy ; Glomerulonephritis/pathology ; Glomerulonephritis/diagnosis ; Prednisolone/administration & dosage ; Prednisolone/therapeutic use ; Rituximab/therapeutic use ; Rituximab/administration & dosage ; Indoles/therapeutic use ; Nephritis, Interstitial/pathology ; Nephritis, Interstitial/diagnosis ; Peroxidase/immunology

Targeting PBK in the fibroblast-to-myofibroblast transition: A novel therapeutic strategy for IPF.

Autori: Dong RH Li X Yue HH a ďalší

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 2), pp. 117283. Date of Electronic Publication: 2025 Aug 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/chemically induced , Fibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/pathology , Myofibroblasts*/drug effects , Myofibroblasts*/metabolism , Myofibroblasts*/pathology, Animals ; Humans ; Mice ; Bleomycin/toxicity ; Male ; Mice, Inbred C57BL ; Female ; Cells, Cultured ; Lung/drug effects ; Lung/pathology ; Cell Differentiation/drug effects

Quantitative HRCT as a surrogate outcome measure for nintedanib treatment in systemic sclerosis-interstitial lung disease and idiopathic pulmonary fibrosis.

Autori: Di Battista M Romei C Tavanti L a ďalší

Zdroj: Joint bone spine [Joint Bone Spine] 2025 Dec; Vol. 92 (6), pp. 105934. Date of Electronic Publication: 2025 Jun 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Elsevier Country of Publication: France NLM ID: 100938016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1778-7254 (Electronic) Linking ISSN: 1297319X NLM ISO Abbreviation: Joint Bone Spine Subsets: MEDLINE

Výrazy zo slovníka MeSH: Indoles*/therapeutic use , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/diagnostic imaging , Lung Diseases, Interstitial*/drug therapy , Lung Diseases, Interstitial*/diagnostic imaging , Lung Diseases, Interstitial*/etiology , Scleroderma, Systemic*/drug therapy , Scleroderma, Systemic*/complications , Scleroderma, Systemic*/diagnostic imaging , Tomography, X-Ray Computed*/methods, Humans ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Retrospective Studies ; Prospective Studies ; Follow-Up Studies

Identification of DNA damage repair-related diagnostic markers for idiopathic pulmonary fibrosis via WGCNA.

Autori: Rao X Zhou Y Xue J a ďalší

Zdroj: Computational biology and chemistry [Comput Biol Chem] 2025 Dec; Vol. 119, pp. 108563. Date of Electronic Publication: 2025 Jun 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/diagnosis , Idiopathic Pulmonary Fibrosis*/genetics , DNA Repair*/genetics , DNA Damage*/genetics , HMGB2 Protein*/genetics, Humans ; Biomarkers/analysis ; Biomarkers/metabolism ; Protein Interaction Maps ; Gene Regulatory Networks

Sugar restriction in the first 1000 days after conception, and long-term respiratory health: a quasi-experiment study.

Autori: Zheng J Yang C Zhou Z a ďalší

Zdroj: The American journal of clinical nutrition [Am J Clin Nutr] 2025 Dec; Vol. 122 (6), pp. 1759-1768. Date of Electronic Publication: 2025 Oct 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0376027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-3207 (Electronic) Linking ISSN: 00029165 NLM ISO Abbreviation: Am J Clin Nutr Subsets: MEDLINE

Výrazy zo slovníka MeSH: Asthma*/etiology , Asthma*/epidemiology , Pulmonary Disease, Chronic Obstructive*/etiology , Pulmonary Disease, Chronic Obstructive*/epidemiology , Dietary Sugars*/administration & dosage , Dietary Sugars*/adverse effects , Idiopathic Pulmonary Fibrosis*/etiology , Idiopathic Pulmonary Fibrosis*/epidemiology, Humans ; Female ; Male ; Middle Aged ; United Kingdom/epidemiology ; Aged ; Adult ; Pregnancy ; Longitudinal Studies

METTL14-mediated m ⁶ A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis.

Autori: Li D Qian L Du Y a ďalší

Zdroj: Epigenetics [Epigenetics] 2025 Dec; Vol. 20 (1), pp. 2462898. Date of Electronic Publication: 2025 Feb 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265293 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2308 (Electronic) Linking ISSN: 15592294 NLM ISO Abbreviation: Epigenetics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/genetics , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology , Methyltransferases*/genetics , Methyltransferases*/metabolism , Adenosine*/analogs & derivatives , Adenosine*/metabolism , RNA Stability* , Aging*/genetics , Transcription Factors*/genetics , Transcription Factors*/metabolism, Humans ; Animals ; Male ; Mice ; A549 Cells ; RNA, Messenger/metabolism ; RNA, Messenger/genetics ; Bleomycin ; Female ; Aged

Identification of the differences in molecular networks between idiopathic pulmonary fibrosis and lung squamous cell carcinoma using machine learning.

Autori: Nojima Y Mizuguchi K

Zdroj: Computational biology and chemistry [Comput Biol Chem] 2025 Dec; Vol. 119, pp. 108560. Date of Electronic Publication: 2025 Jun 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Idiopathic Pulmonary Fibrosis*/genetics , Idiopathic Pulmonary Fibrosis*/diagnosis , Idiopathic Pulmonary Fibrosis*/metabolism , Machine Learning* , Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/diagnosis , Carcinoma, Squamous Cell*/metabolism , Lung Neoplasms*/genetics , Lung Neoplasms*/diagnosis , Lung Neoplasms*/metabolism , Gene Regulatory Networks*, Humans ; Mutation

Relationship between fibroblastic foci and respiratory function: Does the abundance of fibroblastic foci reflect a recent decline in respiratory function?

Autori: Katsuragawa H Ito H Handa T a ďalší

Zdroj: Annals of diagnostic pathology [Ann Diagn Pathol] 2025 Dec; Vol. 79, pp. 152522. Date of Electronic Publication: 2025 Jun 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: W.B. Saunders Co Country of Publication: United States NLM ID: 9800503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8198 (Electronic) Linking ISSN: 10929134 NLM ISO Abbreviation: Ann Diagn Pathol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lung Diseases, Interstitial*/pathology , Lung Diseases, Interstitial*/physiopathology , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/physiopathology , Fibroblasts*/pathology, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Aged ; Respiratory Function Tests/methods ; Disease Progression ; Lung Transplantation ; Lung/pathology ; Vital Capacity/physiology ; Alveolitis, Extrinsic Allergic/pathology ; Connective Tissue Diseases/pathology ; Pyridones

Standard pulmonary function tests and respiratory oscillometry patterns in hypersensitivity pneumonitis and idiopathic pulmonary fibrosis.

Autori: Wu JKY Xu JJ Numakura T a ďalší

Zdroj: BMJ open respiratory research [BMJ Open Respir Res] 2025 Nov 30; Vol. 12 (1). Date of Electronic Publication: 2025 Nov 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BMJ Publishing Group Ltd & British Thoracic Society Country of Publication: England NLM ID: 101638061 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4439 (Electronic) Linking ISSN: 20524439 NLM ISO Abbreviation: BMJ Open Respir Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alveolitis, Extrinsic Allergic*/physiopathology , Alveolitis, Extrinsic Allergic*/diagnosis , Idiopathic Pulmonary Fibrosis*/physiopathology , Idiopathic Pulmonary Fibrosis*/diagnosis , Oscillometry*/methods , Respiratory Function Tests*/methods, Humans ; Female ; Male ; Aged ; Middle Aged

Echinacoside ameliorates bleomycin-induced idiopathic pulmonary fibrosis by regulating macrophage polarization.

Autori: Zhang Y Fan L Wang M

Zdroj: Journal of molecular histology [J Mol Histol] 2025 Nov 24; Vol. 57 (1), pp. 4. Date of Electronic Publication: 2025 Nov 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 101193653 Publication Model: Electronic Cited Medium: Internet ISSN: 1567-2387 (Electronic) Linking ISSN: 15672379 NLM ISO Abbreviation: J Mol Histol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycosides*/pharmacology , Glycosides*/therapeutic use , Bleomycin*/adverse effects , Idiopathic Pulmonary Fibrosis*/chemically induced , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/metabolism , Macrophages*/drug effects , Macrophages*/metabolism , Macrophage Activation*/drug effects, Animals ; Mice ; Humans ; Cell Line ; Disease Models, Animal ; Lung/pathology ; Lung/drug effects ; Mice, Inbred C57BL ; Male

The differential effects of cAMP mobilizing agents on TGF-β-induced extracellular matrix in human lung-derived fibroblasts: insights into therapeutic targets for lung fibrosis.

Autori: Orfanos S Deeney BT Cao G a ďalší

Zdroj: Respiratory research [Respir Res] 2025 Nov 22; Vol. 26 (1), pp. 328. Date of Electronic Publication: 2025 Nov 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fibroblasts*/drug effects , Fibroblasts*/metabolism , Fibroblasts*/pathology , Cyclic AMP*/metabolism , Extracellular Matrix*/drug effects , Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Lung*/drug effects , Lung*/metabolism , Lung*/pathology , Transforming Growth Factor beta*/pharmacology , Transforming Growth Factor beta*/metabolism , Epoprostenol*/analogs & derivatives , Epoprostenol*/pharmacology , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology , Idiopathic Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/metabolism , Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/pathology, Humans ; Cells, Cultured

Exploring the potential mechanisms of anti-pulmonary fibrosis effects of Luo Han Guo via network pharmacology, molecular docking, and experimental validation.

Autori: Cui Q Liu Y Li Y a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 21; Vol. 15 (1), pp. 41345. Date of Electronic Publication: 2025 Nov 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Molecular Docking Simulation* , Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/chemistry , Drugs, Chinese Herbal*/therapeutic use , Network Pharmacology* , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology, Animals ; Signal Transduction/drug effects ; Humans ; Mice ; Kaempferols/pharmacology ; Male