Výsledky vyhledávání - "Humanized/therapeutic use"

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    Zdroj: Annals of oncology, vol. 36, no. 4, pp. 444-459

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    Zdroj: Cancer Res Commun
    Scientia
    Scientia. Dipòsit d'Informació Digital del Departament de Salut
    instname
    Gambardella, V, Ong, M, Rodriguez-Ruiz, M E, Machiels, J-P, Sanmamed, M F, Galvao, V, Spreafico, A, Renouf, D J, Luen, S J, Galot, R, de Spéville, B D, Calvo, E, Naing, A, Curdt, S, Kolben, T M, Rossmann, E, Tanos, T, Smart, K, Amann, M, Xie, Y, Xu, L, Alcaide, E G, Städler, N, Justies, N, Boetsch, C, Karanikas, V, Schnetzler, G & Rohrberg, K S 2025, ' Safety and Antitumor Activity of a Novel aCD25 Treg Depleter RG6292 as a Single Agent and in Combination with Atezolizumab in Patients with Solid Tumors ', Cancer research communications, vol. 5, no. 3, pp. 422-432 . https://doi.org/10.1158/2767-9764.CRC-24-0638

    Témata: Male, Adult, CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal::Antibodies, Monoclonal, Humanized, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Toxicity Tests::Maximum Tolerated Dose, Maximum Tolerated Dose, Other subheadings::Other subheadings::/therapeutic use, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapéutica::farmacoterapia::protocolos antineoplásicos::terapéutica::farmacoterapia::protocolos de quimioterapia antineoplásica combinada, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Therapeutics::Drug Therapy::Antineoplastic Protocols::Therapeutics::Drug Therapy::Antineoplastic Combined Chemotherapy Protocols, Interleukin-2 Receptor alpha Subunit/metabolism, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::pruebas de toxicidad::dosis máxima tolerada, Otros calificadores::Otros calificadores::/uso terapéutico, COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::proteínas::proteínas sanguíneas::inmunoproteínas::inmunoglobulinas::anticuerpos::anticuerpos monoclonales::anticuerpos monoclonales humanizados, Antineoplastic Combined Chemotherapy Protocols/pharmacology, Antibodies, Monoclonal, Humanized, T-Lymphocytes, Regulatory, Quimioteràpia combinada, DISEASES::Neoplasms, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Humans, Aged, Aged, 80 and over, Other subheadings::Other subheadings::Other subheadings::/drug therapy, Anticossos monoclonals - Ús terapèutic, Càncer - Tractament, Interleukin-2 Receptor alpha Subunit, Middle Aged, Neoplasms/drug therapy, T-Lymphocytes, Regulatory/drug effects, Antibodies, Monoclonal, Humanized/therapeutic use, ENFERMEDADES::neoplasias, Female, Research Article

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    Přispěvatelé: Lopez, Juanita Powles, Thomas Braiteh, Fadi a další

    Zdroj: Nat Med
    NATURE MEDICINE

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    Zdroj: Singh, D, Brightling, C E, Rabe, K F, Han, M K, Christenson, S A, Drummond, M B, Papi, A, Pavord, I D, Molfino, N A, Almqvist, G, Kotalik, A, Hellqvist, Å, Gołąbek, M, Sindhwani, N S, Ponnarambil, S S, COURSE study investigators & Weinreich, U M 2025, 'Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE) : a randomised, placebo-controlled, phase 2a trial', The Lancet. Respiratory Medicine, vol. 13, no. 1, pp. 47-58. https://doi.org/10.1016/S2213-2600(24)00324-2

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    Zdroj: J Neurol
    Journal of neurology, vol. 272, no. 8, pp. 491

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    Přispěvatelé: Kristina Lend Jon Lampa Leonid Padyukov a další

    Zdroj: Ann Rheum Dis
    Lend, K, Lampa, J, Padyukov, L, Hetland, M L, Heiberg, M S, Nordström, D C, Nurmohamed, M T, Rudin, A, Østergaard, M, Haavardsholm, E A, Hørslev-Petersen, K, Uhlig, T, Sokka-Isler, T, Gudbjornsson, B, Grondal, G, Frazzei, G, Christiaans, J, Wolbink, G, Rispens, T, Twisk, J W R & van Vollenhoven, R F 2024, 'Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis : data from a randomised controlled trial', Annals of the Rheumatic Diseases, vol. 83, no. 12. https://doi.org/10.1136/ard-2024-226024
    Lend, K, Lampa, J, Padyukov, L, Hetland, M L, Heiberg, M S, Nordström, D C, Nurmohamed, M T, Rudin, A, Østergaard, M, Haavardsholm, E A, Hørslev-Petersen, K, Uhlig, T, Sokka-Isler, T, Gudbjornsson, B, Grondal, G, Frazzei, G, Christiaans, J, Wolbink, G, Rispens, T, Twisk, J W R & van Vollenhoven, R F 2024, ' Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis : data from a randomised controlled trial ', Annals of the Rheumatic Diseases, vol. 83, no. 12, pp. 1657-1665 . https://doi.org/10.1136/ard-2024-226024

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