Výsledky vyhledávání - "Humanized/therapeutic use"
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1
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Zdroj: Blood Adv
Danilov, A V, Kambhampati Thiruvengadam, S, Linton, K, Cumings, K, Chirikov, V, Mutebi, A, Bains Chawla, S, Chhibber, A, Rivas Navarro, F, Marques Gonçalves, F, Wang, A, Ding, Z, Alshreef, A, Favaro, E, Hoehn, D & Sureda, A 2025, 'Indirect comparison of epcoritamab vs chemoimmunotherapy, mosunetuzumab, or odronextamab in follicular lymphoma', Blood Advances, vol. 9, no. 15, pp. 3754-3765. https://doi.org/10.1182/bloodadvances.2024015274Témata: Adult, Male, Lymphoid Neoplasia, Lymphoma, Humanized/therapeutic use, Middle Aged, Antibodies, Treatment Outcome, Antibodies, Monoclonal, Humanized/therapeutic use, Follicular/drug therapy, Lymphoma, Follicular/drug therapy, Monoclonal, Immunotherapy/methods, Humans, Female, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Aged
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2
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Zdroj: Acta Médica Portuguesa, Vol 38, Iss 5 (2025)
Témata: Medicine (General), R5-920, Antibodies, Monoclonal, Humanized/therapeutic use, Psoriasis/drug therapy, Medicine, Humans, Psoriasis, Interleukin /therapeutic use
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Zdroj: Headache
Headache, vol. 65, no. 7, pp. 1134-1147Témata: Research Submission, Headache Impact Test‐6, drug holiday, chronic and episodic migraine, Humans, Migraine Disorders/drug therapy, Female, Male, Adult, Antibodies, Monoclonal, Humanized/pharmacology, Antibodies, Monoclonal, Humanized/therapeutic use, Antibodies, Monoclonal, Humanized/administration & dosage, Quality of Life, Middle Aged, Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology, Calcitonin Gene-Related Peptide Receptor Antagonists/therapeutic use, Calcitonin Gene-Related Peptide Receptor Antagonists/administration & dosage, Switzerland, Prospective Studies, Patient Reported Outcome Measures, Aged, Retrospective Studies, Impact of Migraine on Partners and Adolescent Children, medication overuse, monthly migraine days
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Zdroj: Annals of oncology, vol. 36, no. 4, pp. 444-459
Témata: Humans, Antibodies, Monoclonal, Humanized/therapeutic use, Female, Male, Retrospective Studies, Middle Aged, Cytokine Release Syndrome/drug therapy, Cytokine Release Syndrome/immunology, Cytokine Release Syndrome/blood, Cytokine Release Syndrome/diagnosis, Cytokine Release Syndrome/chemically induced, Aged, Immune Checkpoint Inhibitors/adverse effects, Lymphohistiocytosis, Hemophagocytic/immunology, Lymphohistiocytosis, Hemophagocytic/drug therapy, Lymphohistiocytosis, Hemophagocytic/diagnosis, Lymphohistiocytosis, Hemophagocytic/chemically induced, Lymphohistiocytosis, Hemophagocytic/blood, Neoplasms/drug therapy, Neoplasms/immunology, Adult, Aged, 80 and over, Sepsis/immunology, Sepsis/diagnosis, Sepsis/drug therapy, Sepsis/blood, Biomarkers/blood, Cytokines/blood, biomarkers, cytokine release syndrome, hemophagocytic lymphohistiocytosis, immune checkpoint inhibitors, immune profiling, sepsis
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Zdroj: Cancer Res Commun
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname
Gambardella, V, Ong, M, Rodriguez-Ruiz, M E, Machiels, J-P, Sanmamed, M F, Galvao, V, Spreafico, A, Renouf, D J, Luen, S J, Galot, R, de Spéville, B D, Calvo, E, Naing, A, Curdt, S, Kolben, T M, Rossmann, E, Tanos, T, Smart, K, Amann, M, Xie, Y, Xu, L, Alcaide, E G, Städler, N, Justies, N, Boetsch, C, Karanikas, V, Schnetzler, G & Rohrberg, K S 2025, ' Safety and Antitumor Activity of a Novel aCD25 Treg Depleter RG6292 as a Single Agent and in Combination with Atezolizumab in Patients with Solid Tumors ', Cancer research communications, vol. 5, no. 3, pp. 422-432 . https://doi.org/10.1158/2767-9764.CRC-24-0638Témata: Male, Adult, CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal::Antibodies, Monoclonal, Humanized, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Toxicity Tests::Maximum Tolerated Dose, Maximum Tolerated Dose, Other subheadings::Other subheadings::/therapeutic use, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapéutica::farmacoterapia::protocolos antineoplásicos::terapéutica::farmacoterapia::protocolos de quimioterapia antineoplásica combinada, Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Therapeutics::Drug Therapy::Antineoplastic Protocols::Therapeutics::Drug Therapy::Antineoplastic Combined Chemotherapy Protocols, Interleukin-2 Receptor alpha Subunit/metabolism, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::pruebas de toxicidad::dosis máxima tolerada, Otros calificadores::Otros calificadores::/uso terapéutico, COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::proteínas::proteínas sanguíneas::inmunoproteínas::inmunoglobulinas::anticuerpos::anticuerpos monoclonales::anticuerpos monoclonales humanizados, Antineoplastic Combined Chemotherapy Protocols/pharmacology, Antibodies, Monoclonal, Humanized, T-Lymphocytes, Regulatory, Quimioteràpia combinada, DISEASES::Neoplasms, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Humans, Aged, Aged, 80 and over, Other subheadings::Other subheadings::Other subheadings::/drug therapy, Anticossos monoclonals - Ús terapèutic, Càncer - Tractament, Interleukin-2 Receptor alpha Subunit, Middle Aged, Neoplasms/drug therapy, T-Lymphocytes, Regulatory/drug effects, Antibodies, Monoclonal, Humanized/therapeutic use, ENFERMEDADES::neoplasias, Female, Research Article
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Zdroj: American journal of kidney diseases, vol. 85, no. 3, pp. 384-388
Témata: [SDV] Life Sciences [q-bio], Humans, Male, Female, Retrospective Studies, Middle Aged, Thrombotic Microangiopathies/therapy, Thrombotic Microangiopathies/drug therapy, Thrombotic Microangiopathies/diagnosis, Adult, Antibodies, Monoclonal, Humanized/therapeutic use, Plasmapheresis, Severity of Illness Index, Aged, Complement Inactivating Agents/therapeutic use, Hemolytic-Uremic Syndrome/therapy, Treatment Outcome, C5-blocker therapy, Complement-mediated hemolytic uremic syndrome, Plasma exchanges, Thrombotic microangiopathies
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Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39342982
https://serval.unil.ch/notice/serval:BIB_BE3E28F2CB46
https://serval.unil.ch/resource/serval:BIB_BE3E28F2CB46.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_BE3E28F2CB466
https://hal.univ-lille.fr/hal-05265004v1/document
https://hal.univ-lille.fr/hal-05265004v1
https://doi.org/10.1053/j.ajkd.2024.06.022 -
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Zdroj: Clin Transl Oncol
Clinical & translational oncology, vol. 27, no. 8, pp. 3535-3542Témata: Brief Research Article, Humans, Female, Uterine Cervical Neoplasms/pathology, Uterine Cervical Neoplasms/drug therapy, Uterine Cervical Neoplasms/mortality, Uterine Cervical Neoplasms/therapy, Retrospective Studies, Middle Aged, Aged, Immunotherapy/methods, Adult, Progression-Free Survival, Antibodies, Monoclonal, Humanized/therapeutic use, Longitudinal Studies, B7-H1 Antigen/analysis, Immune Checkpoint Inhibitors/therapeutic use, Aged, 80 and over, Antineoplastic Agents, Immunological/therapeutic use, Cervical Cancer, Immunotherapy, Metastatic, Objective-Response-Rate, Progression-Free-Survival, Real-World-Evidence, Recurrent
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Zdroj: Nat Med
NATURE MEDICINETémata: atezolizumab, Male, Adult, INCREASES, Medizin, Oncologie, VACCINE, CD8-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes/immunology, Antibodies, Monoclonal, Humanized, THERAPY, Neoplasms/pathology, Sciences de la santé humaine, Article, Antigens, Neoplasm, Neoplasms, Neoplasms/immunology, Antineoplastic Combined Chemotherapy Protocols, Medicine and Health Sciences, Journal Article, Humans, HETEROGENEITY, Human health sciences, Antigens, Neoplasm/immunology, Aged, Aged, 80 and over, Cancer och onkologi, Biochemistry, Genetics and Molecular Biology (all), CTLA-4 BLOCKADE, Biology and Life Sciences, Middle Aged, CANCER, CD8-Positive T-Lymphocytes/drug effects, Neoplasms/drug therapy, Antibodies, Monoclonal, Humanized/therapeutic use, Oncology, Cancer and Oncology, CELLS, Immunotherapy/methods, Female, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Immunotherapy, Antibodies, Monoclonal, Humanized/administration & dosage
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Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39762422
https://dspace.library.uu.nl/handle/1874/460017
https://hdl.handle.net/2268/328378
https://doi.org/10.1038/s41591-024-03334-7
https://biblio.ugent.be/publication/01JQNPTCN4PKBW9FWBK5R9XS5W/file/01JQNVF8RNY77SZSGTDWKT746H
http://doi.org/10.1038/s41591-024-03334-7
http://hdl.handle.net/1854/LU-01JQNPTCN4PKBW9FWBK5R9XS5W
https://biblio.ugent.be/publication/01JQNPTCN4PKBW9FWBK5R9XS5W
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-555329
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85214121815
https://www.ncbi.nlm.nih.gov/pubmed/39762422
https://doi.org/10.1038/s41591-024-03334-7 -
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Zdroj: Journal of thoracic oncology, vol. 20, no. 1, pp. 76-93
Témata: Male, Adult, Humans, Carcinoma, Non-Small-Cell Lung/drug therapy, Carcinoma, Non-Small-Cell Lung/pathology, Carcinoma, Non-Small-Cell Lung/mortality, Lung Neoplasms/drug therapy, Lung Neoplasms/pathology, Lung Neoplasms/mortality, Antibodies, Monoclonal, Humanized/therapeutic use, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Antibodies, Monoclonal/therapeutic use, Female, Middle Aged, Aged, Survival Rate, Follow-Up Studies, Neoplasm Metastasis, Durvalumab, Five-year overall survival, Metastatic NSCLC, POSEIDON, Tremelimumab, Lung Neoplasms, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols
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Zdroj: Ramakrishnan, S, Russell, R E K, Mahmood, H R, Krassowska, K, Melhorn, J, Mwasuku, C, Pavord, I D, Bermejo-Sanchez, L, Howell, I, Mahdi, M, Peterson, S, Bengtsson, T & Bafadhel, M 2025, ' Treating eosinophilic exacerbations of asthma and COPD with benralizumab (ABRA) : a double-blind, double-dummy, active placebo-controlled randomised trial ', The Lancet Respiratory Medicine, vol. 13, no. 1, pp. 59-68 . https://doi.org/10.1016/S2213-2600(24)00299-6
Témata: Prednisolone/administration & dosage, Male, Adult, Asthma/drug therapy, Eosinophils/drug effects, Anti-Asthmatic Agents/therapeutic use, Prednisolone, Middle Aged, Antibodies, Monoclonal, Humanized, Pulmonary Disease, Chronic Obstructive/drug therapy, Asthma, Eosinophils, Pulmonary Disease, Chronic Obstructive, Treatment Outcome, Antibodies, Monoclonal, Humanized/therapeutic use, Double-Blind Method, Disease Progression, Humans, Female, Drug Therapy, Combination, Anti-Asthmatic Agents, Aged
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Zdroj: Singh, D, Brightling, C E, Rabe, K F, Han, M K, Christenson, S A, Drummond, M B, Papi, A, Pavord, I D, Molfino, N A, Almqvist, G, Kotalik, A, Hellqvist, Å, Gołąbek, M, Sindhwani, N S, Ponnarambil, S S, COURSE study investigators & Weinreich, U M 2025, 'Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE) : a randomised, placebo-controlled, phase 2a trial', The Lancet. Respiratory Medicine, vol. 13, no. 1, pp. 47-58. https://doi.org/10.1016/S2213-2600(24)00324-2
Témata: Male, Adult, Aged, 80 and over, Chronic obstructive pulmonary disease (COPD), severe COPD exacerbation, tezepelumab, placebo, Middle Aged, Antibodies, Monoclonal, Humanized, Severity of Illness Index, Pulmonary Disease, Chronic Obstructive/drug therapy, Placebos, Pulmonary Disease, Chronic Obstructive, Treatment Outcome, Antibodies, Monoclonal, Humanized/therapeutic use, Double-Blind Method, Humans, Female, Aged
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Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39653044
https://vbn.aau.dk/da/publications/93c3450b-3645-4b92-b9f8-28a5f2b2eb7a
http://www.scopus.com/inward/record.url?scp=85213514843&partnerID=8YFLogxK
https://doi.org/10.1016/S2213-2600(24)00324-2
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00324-2/abstract
https://hdl.handle.net/11392/2576311
https://doi.org/10.1016/S2213-2600(24)00324-2 -
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Zdroj: Transplantation Proceedings. 57:148-155
Témata: Male, Graft Rejection, Humanized/therapeutic use, Middle Aged, Antibodies, Monoclonal, Humanized, Allografts, Antibodies, Intestinal Diseases, Treatment Outcome, Gastrointestinal Agents, Monoclonal, Chronic Disease, Gastrointestinal Agents/therapeutic use, Humans, Transplantation, Homologous, Intestinal Diseases/surgery
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39638713
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Zdroj: J Neurol
Journal of neurology, vol. 272, no. 8, pp. 491Témata: Smoldering MS, Original Communication, PRLs, PIRA, Teriflunomide, Humans, Nitriles, Crotonates/therapeutic use, Crotonates/pharmacology, Hydroxybutyrates, Toluidines/therapeutic use, Toluidines/pharmacology, Female, Male, Adult, Antibodies, Monoclonal, Humanized/therapeutic use, Antibodies, Monoclonal, Humanized/pharmacology, Multiple Sclerosis, Relapsing-Remitting/drug therapy, Multiple Sclerosis, Relapsing-Remitting/diagnostic imaging, Multiple Sclerosis, Relapsing-Remitting/pathology, Middle Aged, Longitudinal Studies, Immunologic Factors/therapeutic use, Immunologic Factors/pharmacology, Brain/diagnostic imaging, Brain/pathology, Brain/drug effects, Disease Progression, Treatment Outcome, Diffusion Tensor Imaging, Magnetic Resonance Imaging, Follow-Up Studies, Disease-modifying therapies, Ocrelizumab
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Zdroj: Adv Ther
Témata: Male, Adult, Registry, Asthma/drug therapy, Humanized/therapeutic use, Anti-Asthmatic Agents/therapeutic use, Disease burden, Dupilumab, Middle Aged, Severity of Illness Index, Asthma, Lung function, Antibodies, Real-world, Asthma control, Monoclonal, Quality of Life, Humans, Female, Prospective Studies, Registries, Aged, Original Research
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Zdroj: Ann Rheum Dis
Lend, K, Lampa, J, Padyukov, L, Hetland, M L, Heiberg, M S, Nordström, D C, Nurmohamed, M T, Rudin, A, Østergaard, M, Haavardsholm, E A, Hørslev-Petersen, K, Uhlig, T, Sokka-Isler, T, Gudbjornsson, B, Grondal, G, Frazzei, G, Christiaans, J, Wolbink, G, Rispens, T, Twisk, J W R & van Vollenhoven, R F 2024, 'Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis : data from a randomised controlled trial', Annals of the Rheumatic Diseases, vol. 83, no. 12. https://doi.org/10.1136/ard-2024-226024
Lend, K, Lampa, J, Padyukov, L, Hetland, M L, Heiberg, M S, Nordström, D C, Nurmohamed, M T, Rudin, A, Østergaard, M, Haavardsholm, E A, Hørslev-Petersen, K, Uhlig, T, Sokka-Isler, T, Gudbjornsson, B, Grondal, G, Frazzei, G, Christiaans, J, Wolbink, G, Rispens, T, Twisk, J W R & van Vollenhoven, R F 2024, ' Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis : data from a randomised controlled trial ', Annals of the Rheumatic Diseases, vol. 83, no. 12, pp. 1657-1665 . https://doi.org/10.1136/ard-2024-226024Témata: Male, Adult, Methotrexate/therapeutic use, Humanized/therapeutic use, Epitopes/immunology, Antirheumatic Agents/therapeutic use, Rheumatoid Arthritis, Antibodies, Monoclonal, Humanized, Severity of Illness Index, Antibodies, Anti-Citrullinated Protein Antibodies, Rheumatoid/drug therapy, Arthritis, Rheumatoid, Abatacept, Epitopes, Drug Therapy, Rheumatoid Factor, Rheumatoid, Monoclonal, Humans, HLA-DRB1 Chains/genetics, Alleles, Aged, Arthritis, Middle Aged, Certolizumab Pegol/therapeutic use, Anti-Citrullinated Protein Antibodies/blood, General medicine, internal medicine and other clinical medicine, 3. Good health, Biological Therapy, Rheumatoid Factor/blood, Abatacept/therapeutic use, Treatment Outcome, Methotrexate, Antirheumatic Agents, Combination, Certolizumab Pegol, Female, Drug Therapy, Combination, HLA-DRB1 Chains
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Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39079894
https://research.vumc.nl/en/publications/29a841b6-7462-40f3-8111-1f7fed354859
http://hdl.handle.net/10138/584533
https://curis.ku.dk/ws/files/413564336/1657.full.pdf
https://portal.findresearcher.sdu.dk/da/publications/af805c06-6862-49fe-8933-b33cfe953cb4
https://doi.org/10.1136/ard-2024-226024 -
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Zdroj: Clin Rev Allergy Immunol
Témata: 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, On-demand therapy, Angioedemas, Hereditary/diagnosis [MeSH], Humans [MeSH], Systematic review, Treatment Outcome [MeSH], Attack-free rate, Clinical Trials, Phase III as Topic [MeSH], Hereditary angioedema, Antibodies, Monoclonal, Humanized/therapeutic use [MeSH], Complement C1 Inhibitor Protein/therapeutic use [MeSH], Angioedemas, Hereditary/prevention, Review, Long-term prophylaxis, Clinical Trials, Phase III as Topic, Angioedemas, Hereditary, Humans, Antibodies, Monoclonal, Humanized, Complement C1 Inhibitor Protein
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Zdroj: J Neurol
Témata: Leukoencephalitis, Acute Hemorrhagic, Male, Treatment Outcome, Humans, Female, Leukoencephalitis, Acute Hemorrhagic/drug therapy [MeSH], Antibodies, Monoclonal, Humanized/therapeutic use [MeSH], Humans [MeSH], Letter to the Editors, Treatment Outcome [MeSH], Antibodies, Monoclonal, Humanized
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39242371
https://repository.publisso.de/resource/frl:6498401 -
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Zdroj: Future Oncol
Future oncology, vol. 20, no. 27, pp. 1983-1991Témata: Clinical Trial Evaluation, Clinical Trials as Topic, Humans, Antibodies, Monoclonal, Humanized/therapeutic use, Neoplasms/drug therapy, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, PD-1, TIGIT, clinical trials, hematologic, immunotherapy, pembrolizumab, solid tumors, vibostolimab, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Antibodies, Monoclonal, Humanized
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Zdroj: Acta Neurol Belg
Témata: Male, Adult, ddc:610, Dose-Response Relationship, Drug, Migraine Disorders, Dose-Response Relationship, Drug [MeSH], Female [MeSH], Real-world, Aged [MeSH], Adult [MeSH], Humans [MeSH], Treatment Outcome [MeSH], Antibodies, Monoclonal, Humanized/administration, Retrospective Studies [MeSH], Middle Aged [MeSH], Calcitonin Gene-Related Peptide Receptor Antagonists/administration, Original Article, Male [MeSH], Preventive medication, Erenumab, Antibodies, Monoclonal, Humanized/therapeutic use [MeSH], Young Adult [MeSH], Migraine Disorders/drug therapy [MeSH], Migraine, Middle Aged, Antibodies, Monoclonal, Humanized, 3. Good health, Young Adult, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, Calcitonin Gene-Related Peptide Receptor Antagonists, Humans, Female, Retrospective Studies, Aged
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Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39066884
https://repository.publisso.de/resource/frl:6509617 -
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Zdroj: Annals of oncology, vol. 36, no. 1, pp. 43-53
Témata: Male, Aged, 80 and over, Adult, Arthritis, Humans, Antibodies, Monoclonal, Humanized/administration & dosage, Antibodies, Monoclonal, Humanized/therapeutic use, Antibodies, Monoclonal, Humanized/adverse effects, Female, Immune Checkpoint Inhibitors/adverse effects, Immune Checkpoint Inhibitors/administration & dosage, Immune Checkpoint Inhibitors/therapeutic use, Retrospective Studies, Aged, Middle Aged, Arthritis/drug therapy, Prednisone/administration & dosage, Prednisone/therapeutic use, Neoplasms/drug therapy, Neoplasms/pathology, Recurrence, Secondary Prevention/methods, arthritis, immune checkpoint inhibitors, irAEs, secondary prophylaxis, tocilizumab, Antibodies, Monoclonal, Humanized, Neoplasms, Secondary Prevention, Prednisone, Immune Checkpoint Inhibitors
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