Výsledky vyhľadávania - "Histone Deacetylase Inhibitors chemistry"

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin

Autori: Saraiva, Raul G. Huitt-Roehl, Callie R. Tripathi, Abhai a ďalší

Zdroj: Scientific Reports

Predmety: Antibiosis, Antimalarials / chemistry, Antimalarials / metabolism, Antimalarials / pharmacology, Chromobacterium / classification, Chromobacterium / physiology, Depsipeptides / biosynthesis, Depsipeptides / chemistry, Depsipeptides / pharmacology, Genome, Bacterial, Genome-Wide Association Study, Genomics / methods, Histone Deacetylase Inhibitors / chemistry, Histone Deacetylase Inhibitors / metabolism, Histone Deacetylase Inhibitors / pharmacology, Parasitic Sensitivity Tests, Phylogeny, Plasmodium / drug effects, Plasmodium / physiology

Popis súboru: application/pdf

Relation: https://doi.org/10.1038/s41598-018-24296-0; https://hdl.handle.net/20.500.12503/31656

Dostupnosť: https://hdl.handle.net/20.500.12503/31656

Sinus augmentation using a histone deacetylase inhibitor in a calcium sulfate carrier in rabbit: A pilot study: OSTEOGENIC POTENTIAL IN CENTRAL PORTION OF THE AUGMENTED SINUS

Autori: Ui Won Jung Jung Seok Lee Kyung Mi Woo a ďalší

Prispievatelia: Ui Won Jung Jung Seok Lee Kyung Mi Woo a ďalší

Zdroj: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:1916-1923

Predmety: Calcium Sulfate*/chemistry, 0301 basic medicine, Drug Carriers, Drug Carriers*/pharmacology, maxillary sinus augmentation, Drug Carriers*/chemistry, Sinus Floor Augmentation, Histone Deacetylase Inhibitors*/chemistry, animal study, Calcium Sulfate, 3. Good health, calcium sulfate, Histone Deacetylase Inhibitors, 03 medical and health sciences, 0302 clinical medicine, Histone Deacetylase Inhibitors*/pharmacology, Calcium Sulfate*/pharmacology, Animals, sodium butyrate, Rabbits, histone deacetylase inhibitor

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/27283081
http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33727/full
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/jbm.b.33727
https://yonsei.pure.elsevier.com/en/publications/sinus-augmentation-using-a-histone-deacetylase-inhibitor-in-a-cal
https://europepmc.org/article/MED/27283081
https://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33727/full
https://pubmed.ncbi.nlm.nih.gov/27283081/

Aurones as histone deacetylase inhibitors: Identification of key features

Autori: Zwick, Vincent Chatzivasileiou, Alkiviadis-Orfefs Deschamps, Nathalie a ďalší

Zdroj: Bioorganic & Medicinal Chemistry Letters, Vol. 24, No 23 (2014) pp. 5497-501

Predmety: Models, Molecular, 0301 basic medicine, ddc:615, 0303 health sciences, Molecular Structure, Histone Deacetylase Inhibitors/chemistry, Molecular, structure activity relationship, 3. Good health, Histone Deacetylase Inhibitors, 03 medical and health sciences, aurone, Models, Drug Design, docking, Humans, Histone deacetylase, Benzofurans/chemistry, Benzofurans

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/25455492
https://www.ncbi.nlm.nih.gov/pubmed/25455492
https://archive-ouverte.unige.ch/unige:95051
https://www.sciencedirect.com/science/article/pii/S0960894X14010646
http://www.sciencedirect.com/science/article/pii/S0960894X14010646
https://pubmed.ncbi.nlm.nih.gov/25455492/
https://archive-ouverte.unige.ch/unige:95051
https://doi.org/10.1016/j.bmcl.2014.10.019
https://archive-ouverte.unige.ch/unige:95051

Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism: Proteasome and Class I HDAC Inhibitors on NPC

Autori: Hui, KF Chiang, AKS

Zdroj: International Journal of Cancer. 135:2950-2961

Predmety: 0301 basic medicine, Histone Deacetylase Inhibitors - chemistry, Antineoplastic Agents, Apoptosis, Histone Deacetylase 6, Histone Deacetylases, Bortezomib, 03 medical and health sciences, 0302 clinical medicine, Depsipeptides, Proteasome Endopeptidase Complex - chemistry, In Situ Nick-End Labeling, Animals, Humans, Cell Proliferation, Nasopharyngeal Neoplasms - metabolism, 0303 health sciences, Carcinoma, Histone Deacetylases - metabolism, Endoplasmic Reticulum Stress, Fluoresceins, Boronic Acids, 3. Good health, Enzyme Activation, Histone Deacetylase Inhibitors, Caspases, Benzamides, Female, DNA Damage

Prístupová URL adresa: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.28924
https://pubmed.ncbi.nlm.nih.gov/24771510
https://pubmed.ncbi.nlm.nih.gov/24771510/
https://onlinelibrary.wiley.com/doi/10.1002/ijc.28924
https://core.ac.uk/display/38046740
http://hub.hku.hk/handle/10722/198062
https://europepmc.org/abstract/MED/24771510
https://www.ncbi.nlm.nih.gov/pubmed/24771510/
http://hdl.handle.net/10722/198062

Lactam‐Based HDAC Inhibitors for Anticancer Chemotherapy: Restoration of RUNX3 by Posttranslational Modification and Epigenetic Control

Autori: Misun Cho Hyun-Jung Kim Kim Hwan a ďalší

Prispievatelia: Misun Cho Hyun-Jung Kim Kim Hwan a ďalší

Zdroj: ChemMedChem. 9:649-656

Predmety: Experimental/drug therapy, Models, Molecular, 0301 basic medicine, Nude, Molecular Conformation, Messenger/metabolism, Epigenesis, Genetic, Cell Proliferation/drug effects, Mice, Models, Neoplasms, Antineoplastic Agents/chemistry, inhibitors, Experimental/pathology, Lactams/pharmacology, Antineoplastic Agents/chemical synthesis, Protein Stability, Histone Deacetylase Inhibitors/chemistry, Core Binding Factor Alpha 3 Subunit/chemistry, 16. Peace & justice, 3. Good health, lactam, Core Binding Factor Alpha 3 Subunit/genetics, Drug, Lactams/chemical synthesis, Core Binding Factor Alpha 3 Subunit/antagonists & inhibitors, Histone Deacetylase Inhibitors/chemical synthesis, Lactams, Histone Deacetylase Inhibitors/pharmacology, Mice, Nude, Antineoplastic Agents, Histone Deacetylases/metabolism, Histone Deacetylases, drug discovery, Dose-Response Relationship, Antineoplastic Agents/pharmacology, Structure-Activity Relationship, 03 medical and health sciences, Protein Stability/drug effects, Animals, RNA, Messenger, Experimental/metabolism, Cell Proliferation, Dose-Response Relationship, Drug, Core Binding Factor Alpha 3 Subunit/metabolism, Gene Expression Profiling, Molecular, Neoplasms, Experimental, Lactams/chemistry, Xenograft Model Antitumor Assays, Histone Deacetylase Inhibitors, Core Binding Factor Alpha 3 Subunit, runt-related transcription factor 3, histone deacetylase, RNA, Messenger/genetics, Genetic/drug effects, Epigenesis, Messenger/antagonists & inhibitors

Popis súboru: 649~656

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/24376239
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.201300393
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12813
https://www.ncbi.nlm.nih.gov/pubmed/24376239
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.201300393
https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201300393
https://pubmed.ncbi.nlm.nih.gov/24376239/

Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia

Autori: Gottesfeld, Joel M Rusche, James R Pandolfo, Massimo

Zdroj: Journal of Neurochemistry

Predmety: 0301 basic medicine, Clinical Trials as Topic, Iron-Binding Proteins -- biosynthesis -- drug effects -- genetics, Frataxin, Gene Expression -- physiology, heterochromatin, Friedreich's ataxia, Gene Expression, Heterochromatin -- metabolism, 3. Good health, Histone Deacetylase Inhibitors, Mice, Structure-Activity Relationship, 03 medical and health sciences, Neurologie, Heterochromatin, Iron-Binding Proteins, Histone Deacetylase Inhibitors -- chemistry -- therapeutic use, Animals, Humans, Gene Silencing, neurodegenerative disorder, histone deacetylase inhibitor

Popis súboru: 1 full-text file(s): application/pdf

Prístupová URL adresa: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12302
https://pubmed.ncbi.nlm.nih.gov/23859350
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766837/
https://www.ncbi.nlm.nih.gov/pmc/PMC3766837
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jnc.12302
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.12302
http://europepmc.org/articles/PMC3766837
http://onlinelibrary.wiley.com/doi/10.1111/jnc.12302/abstract

How the flexibility of human histone deacetylases influences ligand binding: an overview.

Autori: Deschamps, N. Simões-Pires, C.A. Carrupt, P.A. a ďalší

Predmety: Animals, Binding Sites, Catalytic Domain, Drug Design, Histone Deacetylase Inhibitors/chemistry, Histone Deacetylase Inhibitors/metabolism, Histone Deacetylases/chemistry, Histone Deacetylases/metabolism, Humans, Isoenzymes, Ligands, Models, Molecular, Protein Binding, Protein Conformation, Structure-Activity Relationship, Substrate Specificity

Relation: Drug Discovery Today; https://iris.unil.ch/handle/iris/161932; serval:BIB_B0902461421B

Dostupnosť: https://iris.unil.ch/handle/iris/161932
https://doi.org/10.1016/j.drudis.2015.01.004