Search Results - "High-Throughput Screening Assays/methods"
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1
Authors: et al.
Source: Journal of Pharmaceutical Sciences
Subject Terms: Oral, Molecularly dissolved drug, Riluzole, Bile salts, Permeation, Permeability, Workflow, Solubility, Intestinal Absorption, Administration, Solubilization, Humans, High-Throughput Screening Assays/methods, Biorelevant media, Micelles
Access URL: https://pubmed.ncbi.nlm.nih.gov/39730032
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2
Authors: et al.
Source: J Neurooncol
Subject Terms: Female [MeSH], Brain Neoplasms/secondary [MeSH], Spheroid cultures, Brain Neoplasms/genetics [MeSH], Humans [MeSH], Antineoplastic Agents/pharmacology [MeSH], Middle Aged [MeSH], Tumor Cells, Cultured [MeSH], Personalized medicine, Drug Screening Assays, Antitumor/methods [MeSH], High-Throughput Screening Assays/methods [MeSH], Male [MeSH], High-throughput drug screening, Research, Brain metastasis, Antineoplastic Agents/therapeutic use [MeSH], Brain Neoplasms/drug therapy [MeSH], Brain Neoplasms/pathology [MeSH], High-Throughput Nucleotide Sequencing [MeSH], Male, 0301 basic medicine, Brain Neoplasms, High-Throughput Nucleotide Sequencing, Antineoplastic Agents, Middle Aged, High-Throughput Screening Assays, 03 medical and health sciences, 0302 clinical medicine, Tumor Cells, Cultured, Humans, Female, Drug Screening Assays, Antitumor
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3
Authors: et al.
Source: Arch Toxicol
Archives of toxicology 98(8), 2659-2676 (2024). doi:10.1007/s00204-024-03764-9
Archives of ToxicologySubject Terms: 0301 basic medicine, 0303 health sciences, Administration, Oral, In Silico, Models, Biological, Humans [MeSH], Pharmaceutical Preparations/metabolism [MeSH], Computer Simulation [MeSH], Physiologically based kinetic (PBK) modelling, Models, Biological [MeSH], Animals [MeSH], New approach methodologies (NAMs), Administration, Oral [MeSH], Administration, Intravenous [MeSH], High-Throughput Screening Assays/methods [MeSH], Pharmaceutical Preparations/administration, Next-generation risk assessment (NGRA), Pharmacokinetics, Pharmacokinetics [MeSH], High-throughput PBK modelling, High-Throughput Screening Assays, 03 medical and health sciences, Pharmaceutical Preparations, Humans, Animals, Computer Simulation, Administration, Intravenous
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4
Authors: et al.
Contributors: et al.
Subject Terms: Nuisance compounds, Assay design, High-Throughput Screening Assays/methods, Counter screens, Quality assurance, In silico evaluation, Orthogonal assays, Compound quality, Reagent quality
Relation: https://zenodo.org/communities/remedi4all/; https://zenodo.org/records/14872023; oai:zenodo.org:14872023; https://doi.org/10.5281/zenodo.14872023
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5
Authors: et al.
Contributors: et al.
Source: Journal of visualized experiments
Subject Terms: Mycobacterium abscessus / drug effects, Mycobacterium abscessus, Pharmacology. Therapy, Mycobacterium Infections, Nontuberculous / microbiology, Drug Evaluation, Preclinical, Mycobacterium Infections, Nontuberculous, Anti-Bacterial Agents / pharmacology, Mycobacterium Infections, Nontuberculous / drug therapy, High-Throughput Screening Assays, Anti-Bacterial Agents, High-Throughput Screening Assays / methods, Drug Evaluation, Preclinical / methods, Anti-Bacterial Agents / chemistry, Humans
File Description: application/pdf
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6
Authors: et al.
Source: Journal of Visualized Experiments
Subject Terms: 106031 Plant physiology, 2. Zero hunger, Physiological/physiology, 106031 Pflanzenphysiologie, Solanum tuberosum/physiology, 15. Life on land, Stress, 6. Clean water, Droughts, High-Throughput Screening Assays, Phenotype, Stress, Physiological, 13. Climate action, SDG 13 – Maßnahmen zum Klimaschutz, SDG 13 - Climate Action, Life Science, High-Throughput Screening Assays/methods, Solanum tuberosum
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7
Authors: et al.
Source: Nature Communications, 15 (1), 7205 (2024-08-22)
Subject Terms: Humans, High-Throughput Screening Assays/methods, Circadian Clocks/drug effects, Circadian Clocks/genetics, Antineoplastic Agents/pharmacology, Circadian Rhythm/drug effects, Phenotype, Life sciences, Sciences du vivant
Relation: https://www.nature.com/articles/s41467-024-51611-3.pdf; urn:issn:2041-1723; https://orbilu.uni.lu/handle/10993/61871; info:hdl:10993/61871; info:pmid:39169017
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8
Authors: et al.
Source: Oncogene
Subject Terms: Carcinoma, Merkel Cell, 0301 basic medicine, Tumor Virus Infections, 0303 health sciences, 03 medical and health sciences, Carcinoma, Merkel Cell/genetics [MeSH], DNA Methylation/genetics [MeSH], Cancer of unknown primary, Article, High-Throughput Screening Assays/methods [MeSH], Humans [MeSH], Tumor Virus Infections/genetics [MeSH], High-throughput screening, Cancer genomics, Medizin, Humans, DNA Methylation, Biologie, High-Throughput Screening Assays, 3. Good health
Access URL: https://www.nature.com/articles/s41388-021-02064-1.pdf
https://pubmed.ncbi.nlm.nih.gov/34667274
https://www.nature.com/articles/s41388-021-02064-1
https://www.nature.com/articles/s41388-021-02064-1.pdf
https://inrepo01.inet.dkfz-heidelberg.de/record/177113?ln=de
https://pubmed.ncbi.nlm.nih.gov/34667274/?fc=None&ff=20211021030118&v=2.15.0
https://pubmed.ncbi.nlm.nih.gov/34667274/
https://repository.publisso.de/resource/frl:6443672
https://www.ncbi.nlm.nih.gov/pubmed/34667274
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85117303152
https://doi.org/10.1038/s41388-021-02064-1 -
9
Authors: et al.
Contributors: et al.
Source: Journal of Neurochemistry. 157:1270-1283
Subject Terms: Male, 0301 basic medicine, Messenger, Cyclophilins/analysis, Alzheimer's Disease, Biochemistry, Workflow, Cyclophilins, Essential, Immunohistochemistry/methods, 80 and over, High-Throughput Screening Assays/methods, Human health sciences, In Situ Hybridization, In Situ Hybridization, Fluorescence, Aged, 80 and over, 0303 health sciences, Genes, Essential, RNA, Messenger/analysis, In Situ Hybridization, Fluorescence/methods, DNA-Directed RNA Polymerases, Middle Aged, Immunohistochemistry, 3. Good health, Neurology, immunohistochemistry, Female, cyclophilin B, housekeeping genes, POLR2A RNA polymerase, human, automated analysis workflow, Sciences de la santé humaine, Fluorescence, Cellular and Molecular Neuroscience, 03 medical and health sciences, ubiquitin C (UBC), Alzheimer Disease, Neurologie, Humans, RNA, Messenger, DNA-Directed RNA Polymerases/analysis, Aged, Gene Expression Profiling, Ubiquitin C/analysis, High-Throughput Screening Assays, Genes, RNA, Ubiquitin C, in situ hybridization, Gene Expression Profiling/methods, Transcriptome
File Description: Print-Electronic; application/pdf
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10
Authors: et al.
Contributors: et al.
Source: De Cesare, V & Davies, P 2023, High-Throughput MALDI-TOF Mass Spectrometry-Based Deubiquitylating Enzyme Assay for Drug Discovery. in J Maupin-Furlow & M J Edelmann (eds), Deubiquitinases : Methods and Protocols. 1 edn, Methods in Molecular Biology, vol. 2591, Humana Press, New York, pp. 123-134. https://doi.org/10.1007/978-1-0716-2803-4_8
Subject Terms: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods, High-Throughput Screening Assays/methods, Drug Discovery/methods, Ubiquitin/metabolism, Enzyme Assays, Ubiquitin, DUBs, Deubiquitylating enzyme, High-throughput screening, MALDI-TOF mass spectrometry, Drug discovery, /dk/atira/pure/subjectarea/asjc/1300/1311, name=Genetics, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology
File Description: application/pdf
Relation: info:eu-repo/semantics/altIdentifier/pmid/36350546; info:eu-repo/semantics/altIdentifier/isbn/9781071628027; urn:ISBN:9781071628027
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11
Authors:
Subject Terms: Animals, Cell Line, Frizzled Receptors/metabolism, High-Throughput Screening Assays/methods, Humans, Neoplasms/metabolism, Cancer, Drug discovery, Frizzled, GPCR, High throughput
Relation: Methods in cell biology; G Protein-Coupled Receptors, Part B; https://iris.unil.ch/handle/iris/36531; serval:BIB_4F1AA003592A; 000501576100005
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12
Authors: et al.
Source: Marshall, J R, Yao, P, Montgomery, S L, Finnigan, J D, Thorpe, T W, Palmer, R B, Mangas-sanchez, J, Duncan, R A M, Heath, R S, Graham, K M, Cook, D J, Charnock, S J & Turner, N J 2020, 'Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination', Nature Chemistry, vol. 13, no. 2, 0, pp. 140-148. https://doi.org/10.1038/s41557-020-00606-w
Nature ChemistrySubject Terms: Oxidoreductases/isolation & purification, Ketones/chemistry, Amination/drug effects, Stereoisomerism, Ketones, Imines/metabolism, 01 natural sciences, High-Throughput Screening Assays, 0104 chemical sciences, Biocatalysis, High-Throughput Screening Assays/methods, Imines, Amines, Oxidoreductases, Amines/chemistry, Amination
File Description: application/vnd.openxmlformats-officedocument.wordprocessingml.document
Access URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116802
https://pubmed.ncbi.nlm.nih.gov/33380742
https://www.nature.com/articles/s41557-020-00606-w
https://www.nature.com/articles/s41557-020-00606-w.pdf
https://ui.adsabs.harvard.edu/abs/2021NatCh..13..140M/abstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116802
https://www.scilit.net/article/e7277f2bde1fa3f6c997e5508cae0a7d
https://pubmed.ncbi.nlm.nih.gov/33380742/
https://pure.manchester.ac.uk/ws/files/210413902/Marhshall_Nature_Chem.docx
http://www.nature.com/articles/s41557-020-00606-w
https://doi.org/10.1038/s41557-020-00606-w
http://www.scopus.com/inward/record.url?scp=85098498706&partnerID=8YFLogxK
https://research.manchester.ac.uk/en/publications/db043d23-a5ed-4042-83fb-88daa3f5a4f8 -
13
Authors: et al.
Source: SLAS Discov
SLAS discovery, vol. 25, no. 5, pp. 458-470Subject Terms: 0301 basic medicine, Biological Products, Microscopy, 0303 health sciences, Holography, Receptors, GABA-A, Article, 3. Good health, Electrophysiological Phenomena, High-Throughput Screening Assays, Molecular Imaging, 03 medical and health sciences, Biological Products/chemistry, Biological Products/isolation & purification, GABA-A Receptor Agonists/chemistry, GABA-A Receptor Agonists/isolation & purification, GABA-A Receptor Antagonists/chemistry, GABA-A Receptor Antagonists/isolation & purification, High-Throughput Screening Assays/methods, Humans, Image Processing, Computer-Assisted/methods, Molecular Imaging/methods, Receptors, GABA-A/genetics, gamma-Aminobutyric Acid/genetics, gamma-Aminobutyric Acid/metabolism, GABAA, digital holographic microscopy, high-content screening, ligand-gated ion channels, quantitative phase imaging, Image Processing, Computer-Assisted, GABA-A Receptor Agonists, GABA-A Receptor Antagonists, gamma-Aminobutyric Acid
File Description: application/pdf
Access URL: https://europepmc.org/articles/pmc7243081?pdf=render
https://pubmed.ncbi.nlm.nih.gov/31779505
https://europepmc.org/article/MED/31779505
https://journals.sagepub.com/doi/10.1177/2472555219887142
https://journals.sagepub.com/doi/pdf/10.1177/2472555219887142
https://sage.figshare.com/collections/Image-Based_Marker-Free_Screening_of_GABA_sub_A_sub_Agonists_Antagonists_and_Modulators/4764665
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243081
http://journals.sagepub.com/doi/10.1177/2472555219887142
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B3EBACB8FB727
https://serval.unil.ch/resource/serval:BIB_B3EBACB8FB72.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_B3EBACB8FB72 -
14
Authors: et al.
Contributors: et al.
Source: Nature Chemical Biology. 16:577-586
Subject Terms: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung/drug therapy, Drug Resistance, Drug Resistance, Neoplasm/genetics, Non-Small-Cell Lung/drug therapy, Cell Line, Small Molecule Libraries, Genes, Reporter, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Taverne, ErbB Receptors/antagonists & inhibitors, Small Molecule Libraries/pharmacology, Drug Discovery, High-Throughput Screening Assays/methods, Humans, Luciferases/genetics, Phosphorylation, Lung Neoplasms/drug therapy, Luciferases, Reporter, Protein Kinase Inhibitors, Tumor, Neoplasm/genetics, CHECKPOINT KINASE INHIBITOR, PHASE-I, PROTEIN, RESISTANCE, FLT3, AZD7762, AZD9291, Carcinoma, Phosphorylation/drug effects, Reproducibility of Results, Staurosporine, High-Throughput Screening Assays, 3. Good health, ErbB Receptors, Genes, Drug Resistance, Neoplasm, Protein Kinase Inhibitors/pharmacology, DNA Nucleotidyltransferases/genetics, DNA Nucleotidyltransferases, Mutation, Staurosporine/analogs & derivatives
File Description: application/pdf
Access URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123931
https://pubmed.ncbi.nlm.nih.gov/32094923
https://research-portal.uu.nl/en/publications/8c84db43-d226-43a0-8d45-c8c22e72ac39
https://doi.org/10.1038/s41589-020-0484-2
https://research.unipg.it/handle/11391/1469224
https://pubmed.ncbi.nlm.nih.gov/32094923/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123931/
https://www.nature.com/articles/s41589-020-0484-2.pdf
https://www.nature.com/articles/s41589-020-0484-2
https://pure.mpg.de/pubman/faces/ViewItemOverviewPage.jsp?itemId=item_3323730
https://hdl.handle.net/11391/1469224
https://www.nature.com/articles/s41589-020-0484-2
https://doi.org/10.1038/s41589-020-0484-2
https://dspace.library.uu.nl/handle/1874/410302 -
15
Authors: et al.
Subject Terms: Bacterial Proteins/genetics, Bacterial Proteins/immunology, Blotting, Western, Chlamydiales/genetics, Chlamydiales/pathogenicity, Electrophoresis, Gel, Two-Dimensional, Enzyme-Linked Immunosorbent Assay, Gene Expression Regulation, Bacterial, Genome, Bacterial/genetics, High-Throughput Screening Assays/methods, Humans, Proteomics/methods, Recombinant Proteins/metabolism, Sequence Analysis, DNA/methods, Time Factors, Virulence/genetics
File Description: application/pdf
Relation: PLoS ONE; https://iris.unil.ch/handle/iris/90207; serval:BIB_23EB15A4F7BE; 000272998100011
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16
Authors: et al.
Subject Terms: Bacterial Proteins/chemistry, High-Throughput Screening Assays/methods, Hydrolysis, Microwaves, Proteome/chemistry, Proteomics/methods, Staphylococcus aureus/chemistry, Trypsin/chemistry
Relation: Journal of Microbiological Methods; https://iris.unil.ch/handle/iris/233651; serval:BIB_EDA79EF898EA; 000273846600007
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17
Authors: et al.
Subject Terms: Adolescent, Bacteria/genetics, Bacteria/isolation & purification, Bacteria/pathogenicity, Chlamydophila pneumoniae/genetics, Chlamydophila pneumoniae/isolation & purification, Chlamydophila pneumoniae/pathogenicity, DNA, Bacterial/genetics, Female, High-Throughput Screening Assays/methods, Humans, Legionella/genetics, Legionella/isolation & purification, Legionella/pathogenicity, Male, Molecular Diagnostic Techniques/methods, Multiplex Polymerase Chain Reaction/economics, Multiplex Polymerase Chain Reaction/methods, Mycoplasma pneumoniae/genetics, Mycoplasma pneumoniae/isolation & purification, Mycoplasma pneumoniae/pathogenicity, Pneumonia, Bacterial/diagnosis, Bacterial/microbiology, Mycoplasma/diagnosis, Mycoplasma/microbiology, Reagent Kits, Diagnostic, Respiratory Tract Infections/diagnosis
File Description: application/pdf
Relation: International Journal of Medical Microbiology; https://iris.unil.ch/handle/iris/218523; serval:BIB_D7A3ACFF6749; 000443629800001
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18
Authors: et al.
Subject Terms: Genetic Loci/genetics, Genetic Predisposition to Disease, High-Throughput Screening Assays/methods, Humans, Malate Dehydrogenase/genetics, Polymorphism, Single Nucleotide/genetics, Retinitis Pigmentosa/enzymology, Retinitis Pigmentosa/genetics, Sequence Analysis, DNA/methods
File Description: application/pdf
Relation: Molecular Vision; 1090-0535[electronic], 1090-0535[linking]; https://iris.unil.ch/handle/iris/147103; serval:BIB_B92C111FABDE
Availability: https://iris.unil.ch/handle/iris/147103
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19
Authors:
Source: O'Connor, E, Micklefield, J & Cai, Y 2024, 'Searching for the optimal microbial factory : high-throughput biosensors and analytical techniques for screening small molecules', Current Opinion in Biotechnology, vol. 87, pp. 103125. https://doi.org/10.1016/j.copbio.2024.103125
Subject Terms: Small Molecule Libraries, Biological Products, Biosensing Techniques/methods, Biological Products/metabolism, Biotechnology/methods, High-Throughput Screening Assays/methods, Biosensing Techniques, High-Throughput Screening Assays, Biotechnology
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20
Authors: et al.
Source: ACS Combinational Science, Vol. 21, No 3 (2019) pp. 171-182
Subject Terms: 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, Staphylococcus aureus, Halogenation, Cell Survival, Drug Evaluation, Preclinical, Cell Line, 03 medical and health sciences, Curcuma, Cell Line, Tumor, Animals, High-Throughput Screening Assays/methods, Humans, ddc:612, Chromatography, High Pressure Liquid, ddc:615, 0303 health sciences, Molecular Structure, Plant Extracts, Methanol, Polyphenols, 6. Clean water, Anti-Bacterial Agents, 3. Good health, ddc:580, Frizzled Receptors/metabolism, Pseudomonas aeruginosa, Neoplasms/metabolism, Citrus sinensis
File Description: application/pdf
Access URL: https://pubmed.ncbi.nlm.nih.gov/30607939
https://pubmed.ncbi.nlm.nih.gov/30607939/
https://pubs.acs.org/doi/10.1021/acscombsci.8b00132
https://pubs.acs.org/doi/full/10.1021/acscombsci.8b00132
https://archive-ouverte.unige.ch/unige:125518
https://www.ncbi.nlm.nih.gov/pubmed/30607939
https://archive-ouverte.unige.ch/unige:125518
https://archive-ouverte.unige.ch/unige:125518
https://doi.org/10.1021/acscombsci.8b00132
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