Suchergebnisse - "HUMAN growth"

Metabolic factors influencing the efficacy of recombinant human growth hormone therapy in children with short stature.

Autoren: Zhong X Chen Y Liu G et al.

Quelle: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Nov 06; Vol. 16, pp. 1691509. Date of Electronic Publication: 2025 Nov 06 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/therapeutic use , Human Growth Hormone*/deficiency , Body Height*/drug effects , Growth Disorders*/drug therapy , Growth Disorders*/metabolism, Humans ; Male ; Female ; Child ; Retrospective Studies ; Recombinant Proteins/therapeutic use ; Insulin Resistance ; Treatment Outcome ; Child, Preschool ; Insulin/blood ; Blood Glucose ; Adolescent

Efficacy and safety of rhGH in juvenile dermatomyositis children with glucocorticoid-related growth failure.

Autoren: Wang X Huang B Jiang Q et al.

Quelle: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2025 Nov 01; Vol. 64 (11), pp. 5611-5615.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/therapeutic use , Human Growth Hormone*/adverse effects , Glucocorticoids*/adverse effects , Dermatomyositis*/drug therapy , Growth Disorders*/chemically induced , Growth Disorders*/drug therapy, Humans ; Male ; Female ; Child ; Retrospective Studies ; Treatment Outcome ; Adolescent ; Body Height/drug effects ; Child, Preschool ; Recombinant Proteins/therapeutic use ; Recombinant Proteins/adverse effects ; Insulin-Like Growth Factor I/metabolism ; Alkaline Phosphatase/blood

Adult Growth Hormone Deficiency, Replacement Therapy, and Outcomes in Long-Term Childhood Cancer Survivors.

Autoren: Yoshida T Baedke JL Wang H et al.

Quelle: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Oct 16; Vol. 110 (11), pp. e3673-e3684.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

MeSH-Schlagworte: Cancer Survivors*/statistics & numerical data , Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Hormone Replacement Therapy*/statistics & numerical data , Neoplasms*/complications , Growth Disorders*/drug therapy , Growth Disorders*/epidemiology, Humans ; Male ; Female ; Adult ; Insulin-Like Growth Factor I/analysis ; Adolescent ; Cross-Sectional Studies ; Young Adult ; Socioeconomic Factors ; Child ; Quality of Life

Dose optimization of PEG-rhGH therapy to improve growth outcomes of childhood-onset growth failure.

Autoren: Wu Y Zhang L Ma H et al.

Quelle: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society [Growth Horm IGF Res] 2025 Oct; Vol. 82, pp. 101664. Date of Electronic Publication: 2025 Sep 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Scotland NLM ID: 9814320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2238 (Electronic) Linking ISSN: 10966374 NLM ISO Abbreviation: Growth Horm IGF Res Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/administration & dosage , Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Growth Disorders*/drug therapy , Body Height*/drug effects , Polyethylene Glycols*/administration & dosage, Humans ; Child ; Male ; Female ; Retrospective Studies ; Insulin-Like Growth Factor I/analysis ; Insulin-Like Growth Factor I/metabolism ; Adolescent ; Prospective Studies ; Follow-Up Studies ; Child, Preschool ; Dose-Response Relationship, Drug ; Treatment Outcome ; Prognosis

Growth hormone treatment outcomes in children with genetic isolated growth hormone deficiency.

Autoren: Aouchiche K Castets S Oliver Petit I et al.

Quelle: European journal of pediatrics [Eur J Pediatr] 2025 Dec 02; Vol. 184 (12), pp. 812. Date of Electronic Publication: 2025 Dec 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Dwarfism, Pituitary*/drug therapy , Dwarfism, Pituitary*/genetics , Receptors, Pituitary Hormone-Regulating Hormone*/genetics , Receptors, Neuropeptide*/genetics, Humans ; Male ; Retrospective Studies ; Female ; Child, Preschool ; Child ; Treatment Outcome ; Body Height/drug effects ; Follow-Up Studies ; Infant

The 20 kDa isoform of the human growth hormone variant alters adipose and muscle gene expression differently than human growth hormone.

Autoren: Young JA Bogart J Buchman M et al.

Quelle: Journal of neuroendocrinology [J Neuroendocrinol] 2025 Dec; Vol. 37 (12), pp. e70059. Date of Electronic Publication: 2025 Jun 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley & Sons Country of Publication: United States NLM ID: 8913461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2826 (Electronic) Linking ISSN: 09538194 NLM ISO Abbreviation: J Neuroendocrinol Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/pharmacology , Human Growth Hormone*/genetics , Human Growth Hormone*/metabolism , Adipose Tissue*/metabolism , Adipose Tissue*/drug effects , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/drug effects , Gene Expression*/drug effects, Animals ; Mice ; Humans ; Mice, Knockout ; Protein Isoforms/genetics ; Protein Isoforms/pharmacology ; Male ; Transcriptome/drug effects ; Mice, Inbred C57BL

Long-acting Growth Hormone Preparations.

Autoren: Yuen KCJ Boguszewski MCS

Quelle: Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2025 Dec; Vol. 54 (4), pp. 665-684. Date of Electronic Publication: 2025 Jul 22.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 8800104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-4410 (Electronic) Linking ISSN: 08898529 NLM ISO Abbreviation: Endocrinol Metab Clin North Am Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/administration & dosage , Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Growth Disorders*/drug therapy, Humans ; Delayed-Action Preparations ; Child

Growth Hormone Treatment in Patients With KBG Syndrome: Novel Insights, Challenges and Recommendations From Six New Patients and Literature Review.

Autoren: Aukema SM Vandenput K Scarano E et al.

Quelle: American journal of medical genetics. Part A [Am J Med Genet A] 2025 Dec; Vol. 197 (12), pp. e64168. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4833 (Electronic) Linking ISSN: 15524825 NLM ISO Abbreviation: Am J Med Genet A Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/therapeutic use , Human Growth Hormone*/deficiency , Human Growth Hormone*/administration & dosage , Intellectual Disability*/drug therapy , Intellectual Disability*/genetics , Intellectual Disability*/pathology , Abnormalities, Multiple*/drug therapy , Abnormalities, Multiple*/genetics , Abnormalities, Multiple*/pathology , Tooth Abnormalities*/drug therapy , Tooth Abnormalities*/genetics , Tooth Abnormalities*/pathology , Microcephaly*/drug therapy , Microcephaly*/genetics , Microcephaly*/pathology, Humans ; Female ; Child ; Male ; Body Height/drug effects ; Adolescent ; Child, Preschool ; Repressor Proteins/genetics ; Phenotype ; Recombinant Proteins/therapeutic use ; Prader-Willi Syndrome/drug therapy ; Prader-Willi Syndrome/genetics ; Turner Syndrome/drug therapy ; Turner Syndrome/genetics ; Facies ; Bone Diseases, Developmental

SCR Disease Name: KBG syndrome

Development of a Minimum Dataset for the Global Monitoring of the Safety and Efficacy of Growth Hormone Replacement in Adults With Growth Hormone Deficiency (AGHD).

Autoren: Chen SC Lucas-Herald AK Tang R et al.

Quelle: Clinical endocrinology [Clin Endocrinol (Oxf)] 2025 Dec; Vol. 103 (6), pp. 841-851. Date of Electronic Publication: 2025 Jul 21.

Publikationsart: Journal Article; Systematic Review

Info zur Zeitschrift: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 0346653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2265 (Electronic) Linking ISSN: 03000664 NLM ISO Abbreviation: Clin Endocrinol (Oxf) Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Human Growth Hormone*/adverse effects , Hormone Replacement Therapy*/adverse effects , Hormone Replacement Therapy*/methods, Humans ; Adult ; Middle Aged ; Aged ; Female ; Young Adult ; Male ; Aged, 80 and over ; Insulin-Like Growth Factor I/metabolism ; Treatment Outcome

Economic burden of growth hormone deficiency among adults who are at risk for and who have confirmed growth hormone deficiency using US real-world data.

Autoren: Hoffman AR Raveendran S Manjelievskaia J et al.

Quelle: Journal of medical economics [J Med Econ] 2025 Dec; Vol. 28 (1), pp. 1322-1333. Date of Electronic Publication: 2025 Aug 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9892255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-837X (Electronic) Linking ISSN: 13696998 NLM ISO Abbreviation: J Med Econ Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Human Growth Hormone*/economics , Hypopituitarism*/economics , Hypopituitarism*/drug therapy , Hypopituitarism*/diagnosis , Cost of Illness*, Humans ; Female ; Male ; Middle Aged ; Adult ; United States ; Aged ; Insurance Claim Review ; Young Adult ; Patient Acceptance of Health Care/statistics & numerical data ; Health Expenditures/statistics & numerical data

Budget impact analysis of skytrofa for the treatment of pediatric growth hormone deficiency in a US health plan.

Autoren: Boller E Raveendran S Smith A et al.

Quelle: Journal of medical economics [J Med Econ] 2025 Dec; Vol. 28 (1), pp. 1733-1745. Date of Electronic Publication: 2025 Oct 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9892255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-837X (Electronic) Linking ISSN: 13696998 NLM ISO Abbreviation: J Med Econ Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/economics , Human Growth Hormone*/deficiency , Human Growth Hormone*/administration & dosage , Human Growth Hormone*/therapeutic use, Humans ; Child ; United States ; Budgets ; Cost Savings ; Delayed-Action Preparations/economics ; Drug Administration Schedule ; Models, Econometric

Changes in vocal characteristics among children receiving growth hormone treatment due to isolated growth hormone deficiency.

Autoren: Tuysuz O Sutcu ZK Bezgin SU et al.

Quelle: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2025 Dec; Vol. 282 (12), pp. 6383-6391. Date of Electronic Publication: 2025 Oct 24.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Germany NLM ID: 9002937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-4726 (Electronic) Linking ISSN: 09374477 NLM ISO Abbreviation: Eur Arch Otorhinolaryngol Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Voice Quality*/drug effects , Voice Disorders*/physiopathology , Voice Disorders*/etiology, Humans ; Female ; Male ; Child ; Adolescent ; Speech Acoustics ; Puberty ; Cohort Studies

GH replacement therapy in adults stimulates fibroblast activation protein-α activity.

Autoren: Bæk A Pedersen AKN Billeskov TB et al.

Quelle: European journal of endocrinology [Eur J Endocrinol] 2025 Nov 26; Vol. 193 (6), pp. 659-666.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 9423848 Publication Model: Print Cited Medium: Internet ISSN: 1479-683X (Electronic) Linking ISSN: 08044643 NLM ISO Abbreviation: Eur J Endocrinol Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Serine Endopeptidases*/blood , Serine Endopeptidases*/metabolism , Gelatinases*/blood , Gelatinases*/metabolism , Membrane Proteins*/blood , Membrane Proteins*/metabolism , Hormone Replacement Therapy* , Hypopituitarism*/drug therapy , Hypopituitarism*/blood, Humans ; Adult ; Male ; Female ; Middle Aged ; Fibroblast Growth Factors/blood ; Endopeptidases ; Biomarkers/blood ; Collagen/metabolism ; Procollagen/blood ; Young Adult

Metabolic changes after growth hormone treatment in children with growth hormone deficiency and small for gestational age: LG observational study.

Autoren: Kim S Kim SJ Cho KW et al.

Quelle: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Nov 19; Vol. 16, pp. 1661018. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH-Schlagworte: Infant, Small for Gestational Age*/metabolism , Infant, Small for Gestational Age*/growth & development , Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Growth Disorders*/drug therapy , Growth Disorders*/metabolism, Humans ; Female ; Male ; Child ; Body Height/drug effects ; Child, Preschool ; Body Mass Index ; Infant, Newborn ; Follow-Up Studies

Determinants of adverse event occurrence in children with short stature born small for gestational age treated with growth hormone.

Autoren: Coutant R Benchikh N Linglart A et al.

Quelle: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Nov 19; Vol. 16, pp. 1656966. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publikationsart: Journal Article; Observational Study; Multicenter Study

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH-Schlagworte: Infant, Small for Gestational Age*/growth & development , Human Growth Hormone*/adverse effects , Human Growth Hormone*/therapeutic use , Growth Disorders*/drug therapy , Body Height*/drug effects , Dwarfism*/drug therapy , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/etiology, Humans ; Female ; Male ; Child ; Registries ; Infant, Newborn ; Prospective Studies ; Child, Preschool ; France/epidemiology

Impact of Growth Hormone on Skeletal Muscle Strength, Power, Endurance, and Agility in Prepubertal Boys With Short Stature.

Autoren: Malpani A Welch L Plummer D et al.

Quelle: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Nov 18; Vol. 110 (12), pp. 3517-3524.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

MeSH-Schlagworte: Muscle Strength*/drug effects , Muscle Strength*/physiology , Physical Endurance*/drug effects , Muscle, Skeletal*/drug effects , Muscle, Skeletal*/physiology , Human Growth Hormone*/therapeutic use , Human Growth Hormone*/deficiency , Human Growth Hormone*/pharmacology , Growth Disorders*/drug therapy , Growth Disorders*/physiopathology, Humans ; Male ; Child ; Body Height/drug effects ; Energy Metabolism/drug effects

Aromatase Inhibitors Treatment Alone or With GH Increases Final Height in Short-statured Pubertal Boys-Real-world Data.

Autoren: Yackobovitch-Gavan M Tenenbaum A Phillip M et al.

Quelle: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Nov 18; Vol. 110 (12), pp. e4129-e4136.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

MeSH-Schlagworte: Body Height*/drug effects , Aromatase Inhibitors*/therapeutic use , Aromatase Inhibitors*/administration & dosage , Growth Disorders*/drug therapy , Human Growth Hormone*/therapeutic use , Human Growth Hormone*/administration & dosage , Puberty*/drug effects, Humans ; Male ; Retrospective Studies ; Child ; Adolescent ; Drug Therapy, Combination ; Treatment Outcome

Growth Hormone Promotes Hepatic Triglyceride Export in Humans.

Autoren: Baumgartner C Metz M Beghini M et al.

Quelle: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Nov 18; Vol. 110 (12), pp. 3420-3429.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE

MeSH-Schlagworte: Triglycerides*/metabolism , Liver*/metabolism , Liver*/drug effects , Human Growth Hormone*/pharmacology , Human Growth Hormone*/administration & dosage , Acromegaly*/metabolism , Acromegaly*/drug therapy , Acromegaly*/pathology, Humans ; Male ; Adult ; Cross-Over Studies ; Middle Aged ; Lipoproteins, VLDL/metabolism ; Healthy Volunteers ; Receptors, Somatotropin/antagonists & inhibitors ; Lipogenesis/drug effects ; Lipid Metabolism/drug effects

Alterations of lipoprotein subfractions in GH-deficient adults.

Autoren: Ratku B Lőrincz H Csiha S et al.

Quelle: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Nov 05; Vol. 16, pp. 1696426. Date of Electronic Publication: 2025 Nov 05 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/deficiency , Human Growth Hormone*/therapeutic use , Lysophospholipids*/blood , Apolipoproteins M*/blood , Lipoproteins*/blood , Apolipoprotein L1*/blood , Dyslipidemias*/blood , Dyslipidemias*/etiology, Humans ; Male ; Female ; Adult ; Middle Aged ; Sphingosine/analogs & derivatives ; Sphingosine/blood ; Insulin-Like Growth Factor I/metabolism ; Case-Control Studies ; Hormone Replacement Therapy ; Young Adult

Efficacy of different measures of long-acting growth hormone in treating children with short stature.

Autoren: Cai W Wang X Deng Q et al.

Quelle: Biomarkers in medicine [Biomark Med] 2025 Nov; Vol. 19 (21), pp. 1057-1064. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101312535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-0371 (Electronic) Linking ISSN: 17520363 NLM ISO Abbreviation: Biomark Med Subsets: MEDLINE

MeSH-Schlagworte: Human Growth Hormone*/therapeutic use , Human Growth Hormone*/administration & dosage , Growth Disorders*/drug therapy , Growth Disorders*/blood, Humans ; Child ; Female ; Male ; Insulin-Like Growth Factor I/metabolism ; Body Height/drug effects ; Biomarkers/blood ; Treatment Outcome ; Child, Preschool ; Adolescent