Výsledky vyhľadávania - "HIV-1"

Synthesis and evaluation of novel substituted N-(2-phenylbutyl)-5,6,7,8-tetrahydro-quinazolin-4-amines as allosteric modulators of HIV-DAT-tat interaction.

Autori: Nguyen TH Moukha-Chafiq O Karyakarte S a ďalší

Zdroj: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2025 Dec 01; Vol. 128, pp. 130345. Date of Electronic Publication: 2025 Jul 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dopamine Plasma Membrane Transport Proteins*/metabolism , Quinazolines*/chemical synthesis , Quinazolines*/pharmacology , Quinazolines*/chemistry , tat Gene Products, Human Immunodeficiency Virus*/metabolism , HIV-1*/metabolism , HIV-1*/drug effects, Structure-Activity Relationship ; Allosteric Regulation/drug effects ; Humans ; Animals ; CHO Cells ; Cricetulus ; Cricetinae ; Molecular Structure

Gonadocorticoids Have Different Effects on the Expression of Toll-like Receptors When Infected with Various HIV-1 Subtypes.

Autori: Nosik M Ryzhov K Berezhnaya E a ďalší

Zdroj: Viruses [Viruses] 2025 Nov 18; Vol. 17 (11). Date of Electronic Publication: 2025 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/classification , HIV-1*/genetics , HIV-1*/immunology , HIV-1*/physiology , HIV-1*/drug effects , HIV Infections*/virology , HIV Infections*/immunology , HIV Infections*/genetics , Toll-Like Receptors*/genetics , Toll-Like Receptors*/metabolism , Gonadal Steroid Hormones*/pharmacology, Humans ; Female ; Viral Load ; Leukocytes, Mononuclear/virology ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/drug effects ; Toll-Like Receptor 4/genetics ; Adult

Rational design, synthesis, and evaluating primary biological activities of novel HIV-1 protease inhibitors containing heteraryl acetamides as the P2 ligands.

Autori: Meng S Gao Y Yang Q a ďalší

Zdroj: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2025 Nov 01; Vol. 129, pp. 118338. Date of Electronic Publication: 2025 Aug 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Protease Inhibitors*/chemical synthesis , HIV Protease Inhibitors*/pharmacology , HIV Protease Inhibitors*/chemistry , HIV Protease*/metabolism , HIV Protease*/chemistry , Drug Design* , Acetamides*/chemistry , Acetamides*/pharmacology , Acetamides*/chemical synthesis , HIV-1*/drug effects , HIV-1*/enzymology, Structure-Activity Relationship ; Ligands ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Microbial Sensitivity Tests ; Dose-Response Relationship, Drug ; Catalytic Domain

Characterization of Two Novel HIV-1B/CRF01_AE/CRF07_BC Recombinant Forms Among Men Who Have Sex with Men in Hebei Province, China.

Autori: Zhao F Liu Z Jia J a ďalší

Zdroj: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2025 Nov; Vol. 41 (11), pp. 552-558. Date of Electronic Publication: 2025 Sep 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 8709376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-8405 (Electronic) Linking ISSN: 08892229 NLM ISO Abbreviation: AIDS Res Hum Retroviruses Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/classification , HIV-1*/isolation & purification , HIV Infections*/virology , HIV Infections*/epidemiology , Recombination, Genetic* , Homosexuality, Male* , Genotype*, Humans ; China/epidemiology ; Male ; Phylogeny ; Genome, Viral ; Genetic Variation ; Adult ; Sequence Analysis, DNA

Insights About the Structure and Recognition Mechanism of the Rev Response Element of HIV-1 Revealed by FRET-monitored Mutagenesis and Modeling.

Autori: Szewczyk MP Loharch S López-Núñez S a ďalší

Zdroj: Journal of molecular biology [J Mol Biol] 2025 Dec 15; Vol. 437 (24), pp. 169451. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/metabolism , HIV-1*/chemistry , rev Gene Products, Human Immunodeficiency Virus*/chemistry , rev Gene Products, Human Immunodeficiency Virus*/genetics , rev Gene Products, Human Immunodeficiency Virus*/metabolism , Response Elements*/genetics, Fluorescence Resonance Energy Transfer ; Models, Molecular ; RNA, Viral/genetics ; RNA, Viral/chemistry ; RNA, Viral/metabolism ; Humans ; Mutagenesis ; Protein Binding

Siglec14-TLR2 axis mediates anti-HIV-1 immunity in macrophages.

Autori: Shi M Lu B Wei W a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 03; Vol. 166, pp. 115595. Date of Electronic Publication: 2025 Sep 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Toll-Like Receptor 2*/metabolism , Toll-Like Receptor 2*/immunology , HIV-1*/immunology , HIV-1*/physiology , Macrophages*/immunology , Macrophages*/virology , HIV Infections*/immunology , Lectins*/metabolism , Lectins*/genetics , Lectins*/immunology, Humans ; Signal Transduction ; nef Gene Products, Human Immunodeficiency Virus/metabolism ; Immunity, Innate ; Interferon Regulatory Factor-3/metabolism ; Virus Replication ; NF-kappa B/metabolism

Combining spironolactone to antiretroviral therapy accelerates HIV decay in humanized mice.

Autori: Ling L Mori LP Soper A a ďalší

Zdroj: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2589549. Date of Electronic Publication: 2025 Nov 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Infections*/drug therapy , HIV Infections*/virology , HIV Infections*/immunology , HIV-1*/drug effects , HIV-1*/physiology , Spironolactone*/pharmacology , Spironolactone*/administration & dosage , Spironolactone*/therapeutic use , Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/therapeutic use, Animals ; Humans ; Mice ; Disease Models, Animal ; Virus Replication/drug effects ; Virus Latency/drug effects

BACH2 and HIV: partners in crime?

Autori: Armani-Tourret M Lichterfeld M

Zdroj: Trends in immunology [Trends Immunol] 2025 Dec; Vol. 46 (12), pp. 755-757. Date of Electronic Publication: 2025 Nov 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4981 (Electronic) Linking ISSN: 14714906 NLM ISO Abbreviation: Trends Immunol Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Infections*/immunology , HIV Infections*/virology , Basic-Leucine Zipper Transcription Factors*/metabolism , Basic-Leucine Zipper Transcription Factors*/immunology , HIV-1*/immunology , HIV-1*/physiology , CD4-Positive T-Lymphocytes*/immunology , CD4-Positive T-Lymphocytes*/virology, Humans ; Immunologic Memory ; Animals

GABARAP proteins regulate the packaging of HIV-1 genomic RNA into virions.

Autori: Palaric M Versapuech M Judith D a ďalší

Zdroj: EMBO reports [EMBO Rep] 2025 Dec; Vol. 26 (23), pp. 5826-5858. Date of Electronic Publication: 2025 Oct 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/physiology , Microtubule-Associated Proteins*/metabolism , Microtubule-Associated Proteins*/genetics , Virion*/genetics , Virion*/metabolism , RNA, Viral*/genetics , RNA, Viral*/metabolism , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/genetics , Virus Assembly* , Viral Genome Packaging*, Humans ; Apoptosis Regulatory Proteins/metabolism ; Autophagy-Related Protein 8 Family/metabolism ; Autophagy-Related Protein 8 Family/genetics ; HEK293 Cells ; gag Gene Products, Human Immunodeficiency Virus/metabolism ; Autophagy ; HeLa Cells

Analysis of HIV-1 subtypes and drug resistance mutations in people who inject drugs in Aizawl and nearby districts of Mizoram, India.

Autori: Raskar K Thlengliani L Lalbiaknunga A a ďalší

Zdroj: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2478074. Date of Electronic Publication: 2025 Mar 18.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/drug effects , HIV-1*/classification , HIV-1*/isolation & purification , HIV Infections*/virology , HIV Infections*/epidemiology , Drug Resistance, Viral*/genetics , Substance Abuse, Intravenous*/complications, India/epidemiology ; Humans ; Female ; Mutation ; Male ; Phylogeny ; Genotype ; Adult ; Anti-HIV Agents/pharmacology ; pol Gene Products, Human Immunodeficiency Virus/genetics ; Prevalence ; Recombination, Genetic

Validation of high-throughput oxford nanopore technology for HIV-1 transmitted/founder virus identification.

Autori: Byamukama D Ndekezi C Omara D a ďalší

Zdroj: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2025 Dec; Vol. 161, pp. 108138. Date of Electronic Publication: 2025 Oct 17.

Spôsob vydávania: Journal Article; Validation Study

Informácie o časopise: Publisher: Elsevier Country of Publication: Canada NLM ID: 9610933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3511 (Electronic) Linking ISSN: 12019712 NLM ISO Abbreviation: Int J Infect Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/isolation & purification , HIV-1*/classification , HIV Infections*/virology , HIV Infections*/transmission , High-Throughput Nucleotide Sequencing*/methods , Nanopore Sequencing*/methods, Humans ; Phylogeny ; Genome, Viral ; Nanopores

Epidemic dynamics and clinical characteristics of HIV-1 CRF07_BC_N and CRF07_BC_O in Shanghai, 2017-2023.

Autori: Ma Y Zhang M Cao L a ďalší

Zdroj: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2554301. Date of Electronic Publication: 2025 Sep 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/classification , HIV-1*/drug effects , HIV-1*/isolation & purification , HIV Infections*/epidemiology , HIV Infections*/virology , HIV Infections*/transmission, Humans ; China/epidemiology ; Male ; Adult ; Female ; Middle Aged ; Viral Load ; Phylogeny ; Prevalence ; Genotype ; High-Throughput Nucleotide Sequencing ; CD4 Lymphocyte Count ; Epidemics ; Drug Resistance, Viral/genetics ; Genome, Viral ; Young Adult

Zinc C293 as a novel scaffold with dual activity against HIV-1 integrase and reverse transcriptase.

Autori: Sayyed SK Quraishi M Rajasekharan SK a ďalší

Zdroj: Computational biology and chemistry [Comput Biol Chem] 2025 Dec; Vol. 119, pp. 108573. Date of Electronic Publication: 2025 Jun 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Integrase*/metabolism , HIV Reverse Transcriptase*/antagonists & inhibitors , HIV Reverse Transcriptase*/metabolism , HIV Integrase Inhibitors*/pharmacology , HIV Integrase Inhibitors*/chemistry , HIV Integrase Inhibitors*/chemical synthesis , Reverse Transcriptase Inhibitors*/pharmacology , Reverse Transcriptase Inhibitors*/chemistry , Reverse Transcriptase Inhibitors*/chemical synthesis , HIV-1*/drug effects , HIV-1*/enzymology , Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/chemistry, Molecular Docking Simulation ; Humans ; Molecular Dynamics Simulation ; Structure-Activity Relationship ; Molecular Structure ; Microbial Sensitivity Tests

HIV molecular transmission networks among students in Guangxi: unraveling the dynamics of student-driven HIV epidemic.

Autori: Pang X Ma J He Q a ďalší

Zdroj: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2459142. Date of Electronic Publication: 2025 Feb 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Infections*/transmission , HIV Infections*/epidemiology , HIV Infections*/virology , HIV-1*/genetics , HIV-1*/classification , HIV-1*/isolation & purification , Students*/statistics & numerical data , Epidemics*, Humans ; Male ; Adult ; China/epidemiology ; Phylogeny ; Young Adult ; Female ; Adolescent ; pol Gene Products, Human Immunodeficiency Virus/genetics ; Homosexuality, Male ; Genotype ; Bayes Theorem

Highly efficient production of HIV-1 AD8 gp120 in mammalian cells.

Autori: Mathur T Ahmed S Parthasarathy D a ďalší

Zdroj: Journal of virology [J Virol] 2025 Nov 25; Vol. 99 (11), pp. e0135925. Date of Electronic Publication: 2025 Nov 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Envelope Protein gp120*/genetics , HIV Envelope Protein gp120*/biosynthesis , HIV Envelope Protein gp120*/metabolism , HIV-1*/genetics , HIV-1*/metabolism, Humans ; HEK293 Cells ; Cell Line ; Transfection

Single-base m ⁶ A epitranscriptomics reveals novel HIV-1 host interaction targets in primary CD4 ⁺ T cells.

Autori: Huang S Zhao Y Phillips S a ďalší

Zdroj: Journal of virology [J Virol] 2025 Nov 25; Vol. 99 (11), pp. e0153625. Date of Electronic Publication: 2025 Oct 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

Výrazy zo slovníka MeSH: CD4-Positive T-Lymphocytes*/virology , CD4-Positive T-Lymphocytes*/metabolism , HIV-1*/physiology , HIV-1*/genetics , HIV Infections*/virology , HIV Infections*/genetics , HIV Infections*/metabolism , Adenosine*/analogs & derivatives , Adenosine*/metabolism , Adenosine*/genetics , Host-Pathogen Interactions*/genetics , Transcriptome*, Humans ; Methyltransferases/metabolism ; Methyltransferases/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/genetics ; RNA, Viral/metabolism

Diagnostic effectiveness of HIV-1 quantitative nucleic acid assay as a supplementary test for individuals with indeterminate or negative western blot antibody test results - China, 2018-2023.

Autori: Ding M Pan P Wang Y a ďalší

Zdroj: BMC infectious diseases [BMC Infect Dis] 2025 Nov 21; Vol. 25 (1), pp. 1637. Date of Electronic Publication: 2025 Nov 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/immunology , HIV-1*/isolation & purification , HIV Infections*/diagnosis , HIV Infections*/virology , HIV Antibodies*/blood , Nucleic Acid Amplification Techniques*/methods, Humans ; China ; Viral Load ; Female ; Male ; Blotting, Western ; Sensitivity and Specificity ; Adult ; Middle Aged ; Young Adult

Molecular investigation of a new HIV-1 outbreak among people who inject drugs in Greece: evidence for a dense network of HIV-1 transmission.

Autori: Kostaki EG Papadimitriou E Chatzopoulou F a ďalší

Zdroj: Sexually transmitted infections [Sex Transm Infect] 2025 Nov 17; Vol. 101 (8), pp. 513-518. Date of Electronic Publication: 2025 Nov 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9805554 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-3263 (Electronic) Linking ISSN: 13684973 NLM ISO Abbreviation: Sex Transm Infect Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/classification , HIV-1*/isolation & purification , Disease Outbreaks* , HIV Infections*/epidemiology , HIV Infections*/transmission , HIV Infections*/virology , Substance Abuse, Intravenous*/epidemiology , Substance Abuse, Intravenous*/complications , Drug Users*/statistics & numerical data, Humans ; Greece/epidemiology ; Phylogeny ; Male ; Female ; Adult ; Molecular Epidemiology ; Bayes Theorem ; Middle Aged

Characterization of transmitted drug resistance among recently infected HIV-1 men who have sex with men in Hebei Province, China.

Autori: Lu X Dong S Ma L a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 11; Vol. 15 (1), pp. 39382. Date of Electronic Publication: 2025 Nov 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/drug effects , HIV Infections*/transmission , HIV Infections*/epidemiology , HIV Infections*/drug therapy , HIV Infections*/virology , Drug Resistance, Viral*/genetics , Homosexuality, Male* , Anti-HIV Agents*/therapeutic use , Anti-HIV Agents*/pharmacology, Humans ; Male ; China/epidemiology ; Adult ; Cross-Sectional Studies ; Middle Aged ; Phylogeny ; Prevalence ; Young Adult ; RNA, Viral/genetics

Transcription factor BACH2 shapes tissue-resident memory T cell programs to promote HIV-1 persistence.

Autori: Wei Y Ma HK Wong ME a ďalší

Zdroj: Immunity [Immunity] 2025 Nov 11; Vol. 58 (11), pp. 2878-2898.e11. Date of Electronic Publication: 2025 Aug 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

Výrazy zo slovníka MeSH: Basic-Leucine Zipper Transcription Factors*/metabolism , Basic-Leucine Zipper Transcription Factors*/genetics , Basic-Leucine Zipper Transcription Factors*/immunology , HIV-1*/immunology , HIV-1*/physiology , Immunologic Memory* , HIV Infections*/immunology , HIV Infections*/virology , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/virology , Memory T Cells*/immunology , CD4-Positive T-Lymphocytes*/immunology , CD4-Positive T-Lymphocytes*/virology, Humans ; Immunity, Mucosal