Suchergebnisse - "HISTONE acetylation"

Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture.

Autoren: Fukai, Yohsuke T. Tomoya Kujirai Masatoshi Wakamori et al.

Quelle: Science Advances. 11/21/2025, Vol. 11 Issue 47, p1-13. 13p.

Schlagwörter: *CHROMATIN, *HISTONE acetylation, *BIOSYNTHESIS, *EPIGENETICS, *GENOMES

Novel Nitrogen Heterocycle–Hydroxamic Acid Conjugates Demonstrating Potent Anti-Acute Lymphoblastic Leukemia Activity: Induction of Endogenous Apoptosis and G0/G1 Arrest via Regulation of Histone H3 Acetylation and AKT Phosphorylation in Jurkat Cells

Autoren: Wu, Lingjie Zhao, Li Wang, Liping et al.

Quelle: Cells (2073-4409). Nov2025, Vol. 14 Issue 22, p1822. 22p.

Schlagwörter: *LYMPHOBLASTIC leukemia, *HISTONE acetylation, *PROTEIN kinase B, *CELL growth, *HYDROXAMIC acids, *APOPTOSIS, *HISTONE deacetylase inhibitors, *HETEROCYCLIC compounds

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression.

Autoren: An, Chenrui Zhong, Ke Kang, Xiangjin et al.

Quelle: Advanced Science. 11/6/2025, Vol. 12 Issue 41, p1-17. 17p.

Schlagwörter: *EPIGENETICS, *HISTONE acetylation, *RNA methylation, *GENE expression, *PLURIPOTENT stem cells, *REGENERATIVE medicine, *DEVELOPMENTAL biology

Sex‐Related Differences in Histone Acetylation and Tumor Development in a 4‐Nitroquinoline 1‐Oxide and Ethanol‐Induced Oral Squamous Cell Carcinoma Mouse Model.

Autoren: Nazário, Wender Rodrigues Costa, Anaíra Ribeiro Guedes Fonseca de Oliveira Santos, Débora et al.

Quelle: Journal of Oral Pathology & Medicine. Nov2025, Vol. 54 Issue 10, p1074-1084. 11p.

Schlagwörter: *HISTONE acetylation, *CARCINOGENESIS, *ORAL cancer, *EPIGENETICS, *GENE expression, *NITROQUINOLINE oxide, *LABORATORY mice, *SEX factors in disease

Convergent evolution of H4K16ac-mediated dosage compensation in the ZW species Artemia franciscana.

Autoren: Zimmer, Frederic Fox, Annika Maria Pan, Qiaowei et al.

Quelle: PLoS Genetics. 10/9/2025, Vol. 21 Issue 10, p1-30. 30p.

Schlagwörter: *SEX chromosomes, *HISTONE acetylation, *HISTONES, *CONVERGENT evolution, *ARTEMIA, *DEVELOPMENTAL biology

Targeting histone acetylation to enhance somatic embryogenesis in Quercus suber L. Open Access.

Autoren: De-la-Paz, Natalia E Carneros, Elena Pintos, Beatriz et al.

Quelle: Tree Physiology. Oct2025, Vol. 45 Issue 10, p1-17. 17p.

Schlagwörter: *HISTONE acetylation, *SOMATIC embryogenesis, *HISTONE deacetylase inhibitors, *CORK oak, *PLANT breeding, *EPIGENETICS

Crosstalk between chromatin state and ATM signalling in DNA damage-induced transcription stress.

Autoren: Salas-Armenteros, Irene Klunder, Maarten Vermeulen, Wim et al.

Quelle: EMBO Journal. Oct2025, Vol. 44 Issue 19, p5564-5594. 31p.

Schlagwörter: *CHROMATIN, *HISTONE acetylation, *NUCLEIC acid hybridization, *DNA repair, *HISTONE acetyltransferase, *RNA polymerase II

Disruption of histone acetylation homeostasis reveals multilayered chromatin regulation for transcriptional resiliency.

Autoren: Venu, Vrinda Small, Eric M. Roth, Cullen et al.

Quelle: Epigenetics & Chromatin. 10/3/2025, Vol. 18 Issue 1, p1-23. 23p.

Schlagwörter: *HISTONE acetylation, *GENE expression, *EPIGENETICS, *LUNG cancer, *CHROMATIN

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes.

Autoren: Bonifácio, Bruno Sousa Leite, Ariely Barbosa de Castro Nascimento Sousa, Ana Caroline et al.

Quelle: Cell Biology International. Oct2025, Vol. 49 Issue 10, p1301-1318. 18p.

Schlagwörter: *ACETYLATION, *HISTONE acetylation, *EUKARYOTES, *MOLECULAR genetics, *CELL physiology, *CELLULAR signal transduction, *PROKARYOTES, *PROTEIN metabolism

SETD2 suppresses tumorigenesis in a KRAS^G12C-driven lung cancer model, and its catalytic activity is regulated by histone acetylation.

Autoren: Mack, Ricardo J. Flores, Natasha M. Fox, Geoffrey C. et al.

Quelle: eLife. 9/15/2025, p1-17. 17p.

Schlagwörter: *LUNG cancer, *HISTONE acetylation, *HISTONES, *HISTONE methyltransferases, *ONCOGENES, *TUMOR suppressor genes, *EPIGENETICS, *ADENOCARCINOMA

Immunohistochemical Expression of H3K9ac and H3K27ac in Premalignant and Malignant Tongue Lesions of Wild‐Type and Nos2‐Knockout Mice Treated With 4NQO.

Autoren: Costa, Anaíra Ribeiro Guedes Fonseca de Santos, Débora de Oliveira Silva, Mariana Daiani Costa et al.

Quelle: Journal of Oral Pathology & Medicine. Sep2025, Vol. 54 Issue 8, p715-722. 8p.

Schlagwörter: *HISTONE acetylation, *EPIGENETICS, *NITRIC oxide, *PRECANCEROUS conditions, *IMMUNOHISTOCHEMISTRY, *HISTONES, *TONGUE cancer

Histone H3K27 acetylation mediated by KAT8 maintains antiviral trained immunity in shrimp induced by inactivated white spot syndrome virus.

Autoren: Lv, Li-Xia Zhang, Peng Ma, Ying et al.

Quelle: Communications Biology. 8/30/2025, Vol. 8 Issue 1, p1-17. 17p.

Schlagwörter: *HISTONE acetylation, *WHITE spot syndrome virus, *IMMUNOLOGIC memory, *SHRIMP culture, *METABOLIC reprogramming, *ACETYLTRANSFERASES, *TRANSCRIPTION factors

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription.

Autoren: Ma, Yerong Zhang, Yingyi Yang, Weijie et al.

Quelle: Advanced Science. 8/21/2025, Vol. 12 Issue 31, p1-21. 21p.

Schlagwörter: *HISTONE acetylation, *ACETYLCOENZYME A, *INFERTILITY, *EMBRYOLOGY, *ENERGY metabolism, *GENETIC transcription regulation, *EPIGENETICS

Low-dose dietary vorinostat increases brain histone acetylation levels and reduces oxidative stress in an Alzheimer's disease mouse model.

Autoren: Bose, Chhanda Hindle, Ashly Smith, Shane C et al.

Quelle: Journal of Alzheimer's Disease. Aug2025, Vol. 106 Issue 4, p1360-1382. 23p.

Schlagwörter: *ALZHEIMER'S disease, *HISTONE acetylation, *HISTONE deacetylase inhibitors, *LABORATORY mice, *OXIDATIVE stress, *DIET therapy, *NEUROPROTECTIVE agents, *ANALYTICAL biochemistry

Histone acetylation readers Bdf1 and Yaf9 direct SWR1 remodeler to +1 nucleosome.

Autoren: Ranjan, Anand Elalaoui, Ejlal Xiaona Tang et al.

Quelle: Science Advances. 8/8/2025, Vol. 11 Issue 32, p1-14. 14p.

Schlagwörter: *HISTONE acetylation, *CHROMATIN, *BIOCHEMISTRY, *IMMUNOPRECIPITATION, *DNA

Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena.

Autoren: Garg, Jyoti Saettone, Alejandro Nabeel-Shah, Syed et al.

Quelle: Epigenetics & Chromatin. 8/6/2025, Vol. 18 Issue 1, p1-22. 22p.

Schlagwörter: *HISTONE acetylation, *CHROMATIN-remodeling complexes, *TETRAHYMENA, *CHROMATIN, *GENETIC transcription regulation, *BROMODOMAIN-containing proteins

Progress of Acetylation Modification in Plants.

Autoren: Li, Ruiqi Li, Xuezhong He, Ying et al.

Quelle: Agronomy. Aug2025, Vol. 15 Issue 8, p1910. 17p.

Schlagwörter: *ACETYLATION, *HISTONE acetylation, *BOTANY, *GENETIC transcription regulation, *GENE regulatory networks, *POST-translational modification, *CROP improvement

Contribution of reversible histone acetylation to freeze tolerance and recovery in wood frog kidneys.

Autoren: Taiwo, Olawale O. Storey, Kenneth B.

Quelle: Scientific Reports. 7/26/2025, Vol. 15 Issue 1, p1-9. 9p.

Schlagwörter: *WOOD frog, *HISTONE acetylation, *PHYSIOLOGICAL adaptation, *GENE expression, *EPIGENETICS, *ACETYLTRANSFERASES, *HISTONE deacetylase

D-Carvone Inhibits Fusarium oxysporum by Modulating Gene Expression Through Reduced Histone 3 Acetylation.

Autoren: Xue-Jie Qin Tian-Tian Li You Li et al.

Quelle: Phytopathology. Jul2025, Vol. 115 Issue 7, p809-820. 12p.

Schlagwörter: *FUSARIUM oxysporum, *HISTONE acetylation, *AGRICULTURE, *RNA sequencing, *DNA-protein interactions, *ANTIFUNGAL agents, *CARVONE, *GENE expression

Histone Acetylation in Central and Peripheral Nervous System Injuries and Regeneration: Epigenetic Dynamics and Therapeutic Perspectives.

Autoren: Palomés-Borrajo, Georgina Navarro, Xavier Penas, Clara

Quelle: International Journal of Molecular Sciences. Jul2025, Vol. 26 Issue 13, p6277. 24p.

Schlagwörter: *HISTONE acetylation, *NERVOUS system regeneration, *EPIGENETICS, *ACETYLTRANSFERASES, *NEURAL development, *NERVOUS system injuries, *HISTONE deacetylase inhibitors