Suchergebnisse - "Glutamate-Cysteine Ligase/genetics"

Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients.

Autoren: Monin, A. Baumann, P.S. Griffa, A. et al.

Schlagwörter: Adult, Animals, Brain/pathology, Brain/physiopathology, Cells, Cultured, Female, Fibroblasts/metabolism, Glutamate-Cysteine Ligase/genetics, Glutamate-Cysteine Ligase/metabolism, Glutathione/deficiency, Humans, Male, Mice, Knockout, Myelin Sheath/pathology, Myelin Sheath/physiology, Oligodendroglia/pathology, Oligodendroglia/physiology, Proto-Oncogene Proteins c-fyn/metabolism, Rats, Wistar, Schizophrenia/drug therapy, Schizophrenia/pathology, Schizophrenia/physiopathology, White Matter/pathology, White Matter/physiopathology, Young Adult

Dateibeschreibung: application/pdf

Relation: Molecular Psychiatry; https://iris.unil.ch/handle/iris/251139; serval:BIB_E4804562B409; 000356611800005

Verfügbarkeit: https://iris.unil.ch/handle/iris/251139
https://doi.org/10.1038/mp.2014.88

Skin fibroblast model to study an impaired glutathione synthesis: consequences of a genetic polymorphism on the proteome.

Autoren: Gysin, R. Riederer, I.M. Cuénod, M. et al.

Schlagwörter: Adult, Antioxidants/administration & dosage, Biopsy, Blotting, Western, Cells, Cultured, Electrophoresis, Gel, Two-Dimensional, Female, Fibroblasts/metabolism, Glutamate-Cysteine Ligase/genetics, Glutamate-Cysteine Ligase/metabolism, Glutathione/biosynthesis, Humans, Hydroquinones/administration & dosage, Male, Oxidative Stress, Polymorphism, Genetic, Proteome/metabolism, Schizophrenia/genetics, Schizophrenia/metabolism, Sequence Analysis, DNA, Skin, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Relation: Brain Research Bulletin; https://iris.unil.ch/handle/iris/193753; serval:BIB_7BAA49DEE938; 000264791100008

Verfügbarkeit: https://iris.unil.ch/handle/iris/193753
https://doi.org/10.1016/j.brainresbull.2008.10.015

Glutathione Deficit Affects the Integrity and Function of the Fimbria/Fornix and Anterior Commissure in Mice: Relevance for Schizophrenia.

Autoren: Corcoba, A. Steullet, P. Duarte, J.M. et al.

Schlagwörter: Animals, Brain/diagnostic imaging, Brain/growth & development, Brain/pathology, Brain/physiopathology, Diffusion Tensor Imaging, Disease Models, Animal, Glutamate-Cysteine Ligase/deficiency, Glutamate-Cysteine Ligase/genetics, Glutathione/deficiency, Male, Mice, Knockout, Organ Size, Pyrroles, Schizophrenia, Tissue Culture Techniques, White Matter/diagnostic imaging, White Matter/growth & development, White Matter/pathology, White Matter/physiopathology

Dateibeschreibung: application/pdf

Relation: International Journal of Neuropsychopharmacology; https://iris.unil.ch/handle/iris/164138; serval:BIB_8A4015631DF2; 000377108200012

Verfügbarkeit: https://iris.unil.ch/handle/iris/164138
https://doi.org/10.1093/ijnp/pyv110

Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis.

Autoren: Xin, L. Mekle, R. Fournier, M. et al.

Schlagwörter: Adult, Female, Genotype, Glutamate-Cysteine Ligase/genetics, Glutamic Acid/metabolism, Glutathione/metabolism, Glutathione Peroxidase/metabolism, Humans, Magnetic Resonance Spectroscopy, Male, Oxidation-Reduction, Oxidative Coupling, Polymorphism, Genetic, Prefrontal Cortex/diagnostic imaging, Prefrontal Cortex/metabolism, Psychotic Disorders/diagnostic imaging, Psychotic Disorders/metabolism, Young Adult, GCLC, MRS, glutamate, glutathione, glutathione peroxidase, oxidative stress, redox, schizophrenia

Dateibeschreibung: application/pdf

Relation: Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders; https://iris.unil.ch/handle/iris/161586; serval:BIB_C3341BECC5AD; 000386209900015

Verfügbarkeit: https://iris.unil.ch/handle/iris/161586
https://doi.org/10.1093/schbul/sbw038

Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons.

Autoren: Morishita, H. Cabungcal, J.H. Chen, Y. et al.

Schlagwörter: Adaptation, Physiological, Animals, Extracellular Matrix/metabolism, GABAergic Neurons/metabolism, GABAergic Neurons/physiology, Glutamate-Cysteine Ligase/genetics, Interneurons/metabolism, Mice, Inbred C57BL, Microglia/metabolism, Neuronal Plasticity, Oxidation-Reduction, Oxidative Stress, Parvalbumins, Sensory Deprivation/physiology, Visual Cortex/metabolism, Visual Cortex/physiology

Dateibeschreibung: application/pdf

Relation: Biological Psychiatry; https://iris.unil.ch/handle/iris/185787; serval:BIB_CAD2CAEDEA9E; 000359945000007

Verfügbarkeit: https://iris.unil.ch/handle/iris/185787
https://doi.org/10.1016/j.biopsych.2014.12.026

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.

Autoren: Harris, Isaac S Treloar, Aislinn E Inoue, Satoshi et al.

Quelle: Cancer Cell, 27 (2), 211 - 222 (2015-02-09)

Schlagwörter: Antioxidants, Thioredoxins, Glutamate-Cysteine Ligase, Glutathione, Animals, Antioxidants/metabolism, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Carcinogenesis, Female, Glutamate-Cysteine Ligase/genetics, Glutamate-Cysteine Ligase/metabolism, Glutathione/genetics, Humans, Mammary Neoplasms, Animal/drug therapy, Animal/genetics, Animal/pathology, Mice, Transgenic, Thioredoxins/metabolism, Breast Neoplasms, Animal, Oncology, Cancer Research, Cell Biology, Human health sciences, Immunology & infectious disease, Sciences de la santé humaine, Immunologie & maladie infectieuse

Relation: https://api.elsevier.com/content/article/PII:S153561081400470X?httpAccept=text/xml; urn:issn:1535-6108; urn:issn:1878-3686; https://orbilu.uni.lu/handle/10993/57969; info:hdl:10993/57969; https://orbilu.uni.lu/bitstream/10993/57969/1/Harris%20IS%20et%20al_Cancer%20Cell%202015.pdf; info:pmid:25620030; wos:000349515200009

Verfügbarkeit: https://orbilu.uni.lu/handle/10993/57969
https://orbilu.uni.lu/bitstream/10993/57969/1/Harris%20IS%20et%20al_Cancer%20Cell%202015.pdf
https://doi.org/10.1016/j.ccell.2014.11.019

Genetic influences on the retention of inorganic mercury.

Autoren: Custodio, Hipolito Harari, Raul Gerhardsson, Lars et al.

Quelle: Archives of Environmental & Occupational Health; 60(1), pp 17-23 (2005) ; ISSN: 1933-8244

Schlagwörter: Occupational Health and Environmental Health, Gold, Humans, Male, Glutathione Transferase: metabolism, Glutathione Transferase: genetics, Adolescent, Adult, Aged, Air Pollutants, Occupational: toxicity, Occupational: urine, Ecuador, Genotype, Glutamate-Cysteine Ligase: genetics, Glutamate-Cysteine Ligase: metabolism, Occupational: blood, Mercury: blood, Mercury: toxicity, Mercury: urine, Middle Aged, Mining, Occupational Exposure: adverse effects, Polymorphism, Genetic, Research Support, Non-U.S. Gov't

Relation: https://lup.lub.lu.se/record/161129; wos:000238800500003; scopus:33750562864

Verfügbarkeit: https://lup.lub.lu.se/record/161129
https://doi.org/10.3200/AEOH.60.1.17-23