Výsledky vyhľadávania - "Glioblastoma metabolism"

The interplay of mitochondrial dysfunction and altered metabolic pathways in glioblastoma

Autori: Wan Noor Ainun Baharuddin Abdul Yusoff

Zdroj: Contemporary Oncology, Vol 29, Iss 3, Pp 217-231 (2025)

Predmety: glioblastoma metabolism, mitochondrial dysfunction, oxidative phosphorylation, electron transport chain targeting, Medicine

Popis súboru: electronic resource

Relation: https://www.termedia.pl/The-interplay-of-mitochondrial-dysfunction-and-altered-metabolic-pathways-in-glioblastoma,3,56604,1,1.html; https://doaj.org/toc/1428-2526; https://doaj.org/toc/1897-4309

Prístupová URL adresa: https://doaj.org/article/d69581447bf54905b3296da2f7b79985

A proteomic approach supports the clinical relevance of TAT-Cx43266-283 in glioblastoma

Autori: Sara G. Pelaz Raquel Flores-Hernández Tatjana Vujic a ďalší

Zdroj: Translational research, vol. 272, pp. 95-110

Predmety: Glioblastoma/metabolism, Glioblastoma/pathology, Humans, Proteomics/methods, Brain Neoplasms/metabolism, Brain Neoplasms/pathology, Cell Line, Tumor, src-Family Kinases/metabolism, Clinical Relevance, Brain tumors, Cell-penetrating peptides, Connexin, Glioblastoma, Proteomics, Src, src-Family Kinases, Brain Neoplasms

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38876188
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_61BEB1A329563
https://serval.unil.ch/notice/serval:BIB_61BEB1A32956
https://serval.unil.ch/resource/serval:BIB_61BEB1A32956.P001/REF.pdf

Ouroboros: cross-linking protein expression perturbations and cancer histology imaging with generative-predictive modeling: cross-linking protein expression perturbations and cancer histology imaging with generative-predictive modeling

Autori: Srijay Deshpande Sokratia Georgaka Michael Haley a ďalší

Zdroj: Bioinformatics
Deshpande, S, Georgaka, S, Haley, M, Sellers, R, Minshull, J, Nallala, J, Fergie, M, Stone, N, Rajpoot, N, Baker, S M, Iqbal, M, Couper, K, Roncaroli, F & Minhas, F 2024, 'Ouroboros : cross-linking protein expression perturbations and cancer histology imaging with generative-predictive modeling', Bioinformatics (Oxford, England), vol. 40, no. Supplement_2, pp. ii174-ii181. https://doi.org/10.1093/bioinformatics/btae399

Predmety: Image Processing, Computer-Assisted/methods, Brain Neoplasms, Image Processing, Computer-Assisted/methods, Image Processing, Computer-Assisted, Digital Health, Humans, Computational Biology, Glioblastoma/metabolism, Computational Biology/methods, Glioblastoma, Brain Neoplasms/metabolism

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39230703
https://research.manchester.ac.uk/en/publications/d62fb1d8-c128-4302-8650-a7e47eb66d08
https://doi.org/10.1093/bioinformatics/btae399
https://research.manchester.ac.uk/en/publications/d62fb1d8-c128-4302-8650-a7e47eb66d08
http://www.scopus.com/inward/record.url?scp=85203168010&partnerID=8YFLogxK
https://doi.org/10.1093/bioinformatics/btae399

Blood-tumor barrier in focus - investigation of glioblastoma-induced effects on the blood-brain barrier

Autori: Sanjana Mathew-Schmitt Matthias Peindl Philipp Neundorf a ďalší

Zdroj: J Neurooncol

Predmety: 0301 basic medicine, ddc:610, 0303 health sciences, Brain Neoplasms, Research, Induced Pluripotent Stem Cells, Endothelial Cells, Coculture Techniques, 03 medical and health sciences, Blood-Brain Barrier, Spheroids, Cellular, Cell Line, Tumor, Humans, Glioblastoma, Endothelial Cells/pathology [MeSH], Induced Pluripotent Stem Cells [MeSH], Cell Line, Tumor [MeSH], Humans [MeSH], Blood-brain barrier (BBB), Blood-Brain Barrier/pathology [MeSH], Preclinical testing, Glioblastoma/metabolism [MeSH], Glioblastoma/pathology [MeSH], Spheroids, In-vitro models, Blood-Brain Barrier/metabolism [MeSH], Glioblastoma (GBM), Human induced pluripotent stem cells (hiPSCs), Spheroids, Cellular/pathology [MeSH], Coculture Techniques [MeSH], Blood-tumor barrier (BTB), Brain Neoplasms/metabolism [MeSH], Brain Neoplasms/pathology [MeSH]

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39196480
https://repository.publisso.de/resource/frl:6498555

Disrupting glioblastoma networks with tumor treating fields (TTFields) in in vitro models

Autori: Schlieper-Scherf, Steffen Hebach, Nils Hausmann, David a ďalší

Zdroj: J Neurooncol

Predmety: 0301 basic medicine, 0303 health sciences, Brain Neoplasms, Research, Electric Stimulation Therapy, Organoids, 03 medical and health sciences, Cell Line, Tumor, Tumor Cells, Cultured, Humans, Calcium, Glioma, Calcium/metabolism [MeSH], Cell Line, Tumor [MeSH], Cell Proliferation [MeSH], Organoids [MeSH], Humans [MeSH], Cancer cell network, Electric Stimulation Therapy/methods [MeSH], Glioblastoma/metabolism [MeSH], Glioblastoma/pathology [MeSH], Glioblastoma/therapy [MeSH], TTFields, Tumor Cells, Cultured [MeSH], Tumor microtubes, Cancer neuroscience, Brain Neoplasms/pathology [MeSH], Brain Neoplasms/therapy [MeSH], Glioblastoma, Cell Proliferation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39088157
https://repository.publisso.de/resource/frl:6512352

Acute Hypoxia Does Not Alter Tumor Sensitivity to FLASH Radiation Therapy

Autori: Ron J. Leavitt Aymeric Almeida Veljko Grilj a ďalší

Zdroj: International journal of radiation oncology, biology, physics, vol. 119, no. 5, pp. 1493-1505
International journal of radiation oncology, biology, physics

Predmety: Computer. Automation, Lung Neoplasms, Pyridones, Pyrimidinones, Cell Cycle Checkpoints, Carbon Dioxide, Radiation Tolerance, Oxidative Phosphorylation, 3. Good health, Oxygen, Animals, Humans, Mice, Pyrimidinones/pharmacology, Pyrimidinones/therapeutic use, Tumor Hypoxia, Glioblastoma/radiotherapy, Glioblastoma/metabolism, Glycolysis, Pyridones/pharmacology, Pyridones/therapeutic use, Nitroimidazoles, Cell Line, Tumor, Lung Neoplasms/radiotherapy, Lung Neoplasms/pathology, Lung Neoplasms/metabolism, Head and Neck Neoplasms/radiotherapy, Cell Cycle Checkpoints/radiation effects, Oxygen/metabolism, Head and Neck Neoplasms, Human medicine, Glioblastoma

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38387809
https://serval.unil.ch/resource/serval:BIB_44E104806F28.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_44E104806F28
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_44E104806F289
https://repository.uantwerpen.be/docstore/d:irua:24893
https://hdl.handle.net/10067/2076170151162165141

Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene

Autori: Rohini Gupta Melanie Dittmeier Gisela Wohlleben a ďalší

Zdroj: Cancer Gene Ther

Predmety: 0301 basic medicine, 0303 health sciences, Membrane Glycoproteins, Oncogene Proteins, Fusion, Article, 03 medical and health sciences, HEK293 Cells, Cell Movement, Cell Line, Tumor, 14/19, 96/95, Cell Line, Tumor [MeSH], 45/70, 631/337, Glioblastoma/metabolism [MeSH], Glioblastoma/pathology [MeSH], 631/80, 13/109, 45/91, 82/51, Glioblastoma/genetics [MeSH], Membrane Glycoproteins/metabolism [MeSH], Receptor, trkB/metabolism [MeSH], 13/1, Cell Movement/genetics [MeSH], Humans [MeSH], 45/44, Oncogene Proteins, Fusion/genetics [MeSH], Receptor, trkB/genetics [MeSH], Membrane Glycoproteins/genetics [MeSH], HEK293 Cells [MeSH], Signal Transduction [MeSH], Oncogene Proteins, Fusion/metabolism [MeSH], article, Humans, Receptor, trkB, Glioblastoma, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39039193
https://repository.publisso.de/resource/frl:6497759

RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma

Autori: Haidy A. Saleh Nicola Mitwasi Liliana R. Loureiro a ďalší

Zdroj: Cancer Gene Ther

Predmety: 0301 basic medicine, Receptors, Chimeric Antigen, Brain Neoplasms, T-Lymphocytes, Cell Line, Tumor [MeSH], Antibodies, Bispecific/immunology [MeSH], Glioblastoma/immunology [MeSH], T-Lymphocytes/metabolism [MeSH], Receptors, Chimeric Antigen/immunology [MeSH], 13, 42, 692/699/67/580, Glioblastoma/metabolism [MeSH], TWEAK Receptor/metabolism [MeSH], Glioblastoma/pathology [MeSH], 59/5, Receptors, Chimeric Antigen/genetics [MeSH], Xenograft Model Antitumor Assays [MeSH], Killer Cells, Natural/immunology [MeSH], Glioblastoma/genetics [MeSH], 13/1, Killer Cells, Natural/metabolism [MeSH], Brain Neoplasms/genetics [MeSH], T-Lymphocytes/immunology [MeSH], Brain Neoplasms/immunology [MeSH], Humans [MeSH], 101/1, 101, Animals [MeSH], Glioblastoma/therapy [MeSH], TWEAK Receptor/genetics [MeSH], Antibodies, Bispecific/pharmacology [MeSH], Mice [MeSH], Article, 82, 82/1, 59, 692/308/153, Immunotherapy, Adoptive/methods [MeSH], Receptors, Chimeric Antigen/metabolism [MeSH], 14, Brain Neoplasms/metabolism [MeSH], article, Brain Neoplasms/pathology [MeSH], Brain Neoplasms/therapy [MeSH], Xenograft Model Antitumor Assays, Immunotherapy, Adoptive, Killer Cells, Natural, Mice, 03 medical and health sciences, 0302 clinical medicine, TWEAK Receptor, Cell Line, Tumor, Antibodies, Bispecific, Humans, Animals, Glioblastoma

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38582787
https://repository.publisso.de/resource/frl:6497262

Targeting HIF-2α in glioblastoma reshapes the immune infiltrate and enhances response to immune checkpoint blockade

Autori: Espinoza Rojas, Felipe Ignacio Tankov, Stoyan Chliate, Sylvie a ďalší

Zdroj: Cell Mol Life Sci

Predmety: Tumor Microenvironment / drug effects, Basic Helix-Loop-Helix Transcription Factors / genetics, Brain Neoplasms / metabolism, T-Lymphocytes, Regulatory / immunology, Glioblastoma / drug therapy, T-Lymphocytes, Regulatory, Macrophages / immunology, Hypoxia inducible factor, Mice, Tumor-associated macrophage, Basic Helix-Loop-Helix Transcription Factors / antagonists & inhibitors, Brain Neoplasms / pathology, Basic Helix-Loop-Helix Transcription Factors, Tumor Microenvironment, Sulfones, Microglia / immunology, Immune Checkpoint Inhibitors, Glioblastoma / metabolism, Immune Checkpoint Inhibitors / pharmacology, Brain Neoplasms, Glioma, Immune Checkpoint Inhibitors / therapeutic use, Tumor Microenvironment / immunology, Treg, Tumor microenvironment, Brain Neoplasms / drug therapy, Microglia / metabolism, Indans, Original Article, Immunotherapy, Microglia, Macrophages / drug effects, Brain Neoplasms / immunology, Brain tumors, Glioblastoma / pathology, Immune checkpoint inhibitors, Macrophages / metabolism, Cell Line, Tumor, Animals, Humans, Basic Helix-Loop-Helix Transcription Factors / immunology, Glioblastoma / immunology, Macrophages, HIF-2, T-Lymphocytes, Regulatory / metabolism, Microglia / drug effects, Mice, Inbred C57BL, Glioblastoma, Basic Helix-Loop-Helix Transcription Factors / metabolism

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40095115
https://archive-ouverte.unige.ch/unige:184525
https://doi.org/10.1007/s00018-025-05642-8

Cholinergic neuron-to-glioblastoma synapses in a human iPSC-derived co-culture model

Autori: Sun, Y. Wang, X. Zhang, Z. a ďalší

Zdroj: Stem Cell Reports
Stem cell reports, vol. 20, no. 7, pp. 102534

Predmety: Report, Humans, Induced Pluripotent Stem Cells/metabolism, Induced Pluripotent Stem Cells/cytology, Coculture Techniques/methods, Glioblastoma/pathology, Glioblastoma/metabolism, Glioblastoma/genetics, Cholinergic Neurons/metabolism, Cholinergic Neurons/pathology, Synapses/metabolism, Organoids/metabolism, Organoids/pathology, Brain Neoplasms/pathology, Brain Neoplasms/metabolism, Receptor, Muscarinic M3/metabolism, cancer neuroscience, cholinergic neurons, glioblastoma, glioma, human iPSC, neuron-to-glioma synapse, single-cell, synapse, tumor organoids

Popis súboru: application/pdf

Prístupová URL adresa: https://serval.unil.ch/resource/serval:BIB_85759819F3AF.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_85759819F3AF1
https://serval.unil.ch/notice/serval:BIB_85759819F3AF

Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma

Autori: Duraj, Tomás Kalamian, Miriam Zuccoli, Giulio a ďalší

Zdroj: BMC Med
BMC Medicine, Vol 22, Iss 1, Pp 1-49 (2024)

Predmety: 0301 basic medicine, SDG-03: Good health and well-being, SDG-09: Industry, Biomedical Research, Debate, Glutamine, Cancer, Biomedical Research/methods [MeSH], Research design, Energy Metabolism/physiology [MeSH], Humans [MeSH], Brain Neoplasms/diet therapy [MeSH], Glutamine/metabolism [MeSH], Glioblastoma/metabolism [MeSH], Glioblastoma, Glycolysis [MeSH], Glioblastoma/drug therapy [MeSH], Warburg Effect, Precision medicine, Brain Neoplasms/drug therapy [MeSH], Glucose/metabolism [MeSH], Metabolism, Diet, Ketogenic/methods [MeSH], Brain Neoplasms/metabolism [MeSH], Glioblastoma/diet therapy [MeSH], Glutaminolysis, Glucose-ketone index (GKI), 03 medical and health sciences, Glioblastoma (GBM), Humans, innovation and infrastructure, 0303 health sciences, Brain Neoplasms, Glucose, Medicine, Ketogenic metabolic therapy (KMT), Diet, Ketogenic, Energy Metabolism, Glycolysis

Popis súboru: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39639257
https://doaj.org/article/f493bd6a9af94b99a15a8ff738e02f2b
https://repository.publisso.de/resource/frl:6519341

Transcriptional landscape of the interaction of human Mesenchymal Stem Cells with Glioblastoma in bioprinted co-cultures

Autori: Oliver, Lisa Landais, Yuna Gratas, Catherine a ďalší

Prispievatelia: Oliver, Lisa Landais, Yuna Gratas, Catherine a ďalší

Zdroj: Stem Cell Res Ther
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)

Predmety: 0301 basic medicine, MESH: Brain Neoplasms / genetics, MESH: Temozolomide / therapeutic use, Medicine (General), 3D tumor model, [SDV]Life Sciences [q-bio], Response to treatment, QD415-436, Cell Communication, MESH: Brain Neoplasms / metabolism, Biochemistry, MESH: Coculture Techniques, MESH: Glioblastoma / pathology, 03 medical and health sciences, R5-920, MESH: Brain Neoplasms / pathology, Cancer-Associated Fibroblasts, MESH: Glioblastoma / metabolism, MESH: Tumor Microenvironment, MESH: Cell Communication, MESH: Bioprinting / methods, Tumor Microenvironment, Temozolomide, Humans, MESH: Glioblastoma / genetics, 0303 health sciences, MESH: Humans, Brain Neoplasms, MESH: Mesenchymal Stem Cells / cytology, Research, Bioprinting, Mesenchymal Stem Cells, Coculture Techniques, [SDV] Life Sciences [q-bio], MESH: Mesenchymal Stem Cells / metabolism, MESH: Cancer-Associated Fibroblasts / pathology, MESH: Cancer-Associated Fibroblasts / metabolism, Mesenchymal stromal/stem cell, Co-culture, Glioblastoma, MESH: Temozolomide / pharmacology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39538257
https://doaj.org/article/6c267ab48d44485a92ba4348d55c821e

GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma

Autori: Avenel, Inès C.N. Ewald, Jesper D. Ariey-Bonnet, Jérémy a ďalší

Zdroj: Sci Rep
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Avenel, I C N, Ewald, J D, Ariey-Bonnet, J, Kristensen, I H, Petterson, S A, Thesbjerg, M N, Burton, M, Thomassen, M, Wennerberg, K, Michaelsen, S R & Kristensen, B W 2024, ' GDNF/GFRA1 signaling contributes to chemo-and radioresistance in glioblastoma ', Scientific Reports, vol. 14, no. 1, 17639 . https://doi.org/10.1038/s41598-024-68626-x

Predmety: 0301 basic medicine, Glial Cell Line-Derived Neurotrophic Factor Receptors, Glial Cell Line-Derived Neurotrophic Factor/metabolism, Science, Cellular/metabolism, Drug Resistance, Radiation Tolerance, Article, Cell Line, Neoplastic/drug effects, 03 medical and health sciences, Lomustine, Cell Line, Tumor, Spheroids, Cellular, Temozolomide, Humans, Glioblastoma/metabolism, Glial Cell Line-Derived Neurotrophic Factor, Brain Neoplasms/genetics, 0303 health sciences, Tumor, Neoplasm/genetics, Brain Neoplasms, Radiation Tolerance/genetics, Temozolomide/pharmacology, Glial Cell Line-Derived Neurotrophic Factor Receptors/metabolism, 3. Good health, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Drug Resistance, Neoplasm, Lomustine/pharmacology, Medicine, Spheroids, Glioblastoma, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39085346
https://doaj.org/article/bf399aa8474f412ba51abb1b4e7f7711
https://curis.ku.dk/ws/files/401617987/s41598_024_68626_x.pdf
https://portal.findresearcher.sdu.dk/da/publications/ed0642a8-a93c-44ee-88c8-f19b25cac1d8
https://doi.org/10.1038/s41598-024-68626-x

Non-Immune-Mediated, p27-Associated, Growth Inhibition of Glioblastoma by Class-II-Transactivator (CIITA).

Autori: Tan, Anna Katherine Henry, Aurélie Goffart, Nicolas a ďalší

Zdroj: Cells, 13 (22), 1883 (2024-11-14)

Predmety: Class-II-Transactivator, PI3-Akt, STAT3, glioblastoma, proliferation, Trans-Activators, Nuclear Proteins, MHC class II transactivator protein, Cyclin-Dependent Kinase Inhibitor p27, Animals, Humans, Mice, Cell Line, Tumor, Cyclin-Dependent Kinase Inhibitor p27/metabolism, Cyclin-Dependent Kinase Inhibitor p27/genetics, Mice, Nude, Brain Neoplasms/pathology, Brain Neoplasms/genetics, Brain Neoplasms/metabolism, Gene Expression Regulation, Neoplastic, Glioblastoma/pathology, Glioblastoma/genetics, Glioblastoma/metabolism, Cell Proliferation, Trans-Activators/metabolism, Trans-Activators/genetics, Nuclear Proteins/metabolism, Nuclear Proteins/genetics, Brain Neoplasms, Biochemistry, Genetics and Molecular Biology (all), Life sciences, Genetics & genetic processes, Sciences du vivant, Génétique & processus génétiques

Relation: https://www.mdpi.com/2073-4409/13/22/1883/pdf; urn:issn:2073-4409

Prístupová URL adresa: https://orbi.uliege.be/handle/2268/334963

Dual inhibition of CPT1A and G6PD suppresses glioblastoma tumorspheres

Autori: Seo Jin, Kim Soo Jeong, Park Junseong, Park a ďalší

Prispievatelia: Seo Jin, Kim Soo Jeong, Park Junseong, Park a ďalší

Zdroj: Journal of Neuro-Oncology. 160:677-689

Predmety: Glioblastoma* / metabolism, 0301 basic medicine, Glucosephosphate Dehydrogenase / metabolism, Neoplastic Stem Cells / drug effects, Neoplastic Stem Cells / metabolism, Glucosephosphate Dehydrogenase, Neoplastic Stem Cells / pathology, Cell Line, Glucosephosphate Dehydrogenase / genetics, Mice, 03 medical and health sciences, Carnitine palmitoyltransferase 1A, Cell Line, Tumor, Animals, Humans, Glucosephosphate Dehydrogenase / antagonists & inhibitors, Etomoxir, Glucose-6-phosphate dehydrogenase, Carnitine O-Palmitoyltransferase / metabolism, 0303 health sciences, Tumor, Carnitine O-Palmitoyltransferase / genetics, Carnitine O-Palmitoyltransferase, Glioblastoma* / drug therapy, Dehydroepiandrosterone, Dehydroepiandrosterone / therapeutic use, 3. Good health, Glioblastoma* / genetics, Carnitine O-Palmitoyltransferase / antagonists & inhibitors, Neoplastic Stem Cells, Glioblastoma

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36396930

Combining a noble gas with radiotherapy: glutamate receptor antagonist xenon may act as a radiosensitizer in glioblastoma

Autori: Büttner, Thomas Maerevoet, Marielena K. E. Giordano, Frank A. a ďalší

Zdroj: Radiat Oncol
Radiation Oncology, Vol 19, Iss 1, Pp 1-10 (2024)

Predmety: 0301 basic medicine, Radiation-Sensitizing Agents, 0303 health sciences, Xenon, Research, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Glutamate receptors, Glioma, Receptors, N-Methyl-D-Aspartate, 3. Good health, Receptors, N-Methyl-D-Aspartate [MeSH], Humans [MeSH], Radiation-Sensitizing Agents/pharmacology [MeSH], Glioblastoma/metabolism [MeSH], Glioblastoma, Xenon/pharmacology [MeSH], Xenon/metabolism [MeSH], NMDA, Glioblastoma/radiotherapy [MeSH], Memantine [MeSH], Radiation sensitizer, Excitatory Amino Acid Antagonists/pharmacology [MeSH], Memantine, Clonogenic assay, HeLa Cells [MeSH], Radiotherapy, AMPA, Medical physics. Medical radiology. Nuclear medicine, 03 medical and health sciences, Humans, Excitatory Amino Acid Antagonists, RC254-282, HeLa Cells

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38291439
https://doaj.org/article/cbb055185a004cae9b9157c86a5fd41f
https://repository.publisso.de/resource/frl:6507182

Radiosynthesis and Preclinical Evaluation of m-[18F]FET and [18F]FET-OMe as Novel [18F]FET Analogs for Brain Tumor Imaging

Autori: Gröner, Benedikt Hoffmann, Chris Endepols, Heike a ďalší

Predmety: Cell Line, Tumor [MeSH], Large Neutral Amino Acid-Transporter 1/metabolism [MeSH], Tyrosine/chemistry [MeSH], Fluorine Radioisotopes/chemistry [MeSH], Glioblastoma/metabolism [MeSH], Radiopharmaceuticals/chemical synthesis [MeSH], brain tumor imaging, Positron-Emission Tomography/methods [MeSH], Tyrosine/analogs, fluorine-18, Tissue Distribution [MeSH], [, Radiopharmaceuticals/chemistry [MeSH], Brain/diagnostic imaging [MeSH], Radiopharmaceuticals/pharmacokinetics [MeSH], Humans [MeSH], Animals [MeSH], Mice, Nude [MeSH], Mice [MeSH], positron emission tomography, Article, Brain/metabolism [MeSH], Brain Neoplasms/diagnostic imaging [MeSH], Glioblastoma/diagnostic imaging [MeSH], Brain Neoplasms/metabolism [MeSH], radiopharmaceuticals

Prístupová URL adresa: https://repository.publisso.de/resource/frl:6486370

Photophysical Characterization and In Vitro Evaluation of alpha-Mangostin-Loaded HDL Mimetic Nano-Complex in LN-229 Glioblastoma Spheroid Model

Autori: Kapic, Ammar Sabnis, Nirupama A. Dossou, Akpedje S. a ďalší

Zdroj: International Journal of Molecular Sciences

Predmety: 3D spheroid, GBM, LN-229, rHDL, alpha-mangostin, Xanthones / chemistry, Xanthones / pharmacology, Glioblastoma / drug therapy, Glioblastoma / pathology, Glioblastoma / metabolism, Nanoparticles / chemistry, Lipoproteins, HDL / chemistry|Lipoproteins, HDL / metabolism, Spheroids, Cellular / drug effects

Popis súboru: application/pdf

Relation: https://doi.org/10.3390/ijms25137378; https://hdl.handle.net/20.500.12503/32871; 25; 13

Dostupnosť: https://hdl.handle.net/20.500.12503/32871

Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma

Autori: Mohamed E. M. Saeed Onat Kadioglu Henry Johannes Greten a ďalší

Prispievatelia: Mohamed E. M. Saeed Onat Kadioglu Henry Johannes Greten a ďalší

Zdroj: Invest New Drugs

Predmety: Proto-Oncogene Proteins B-raf, 0301 basic medicine, Genotype, 610 Medizin, Antineoplastic Agents, 570 Life sciences, 03 medical and health sciences, Cell Line, Tumor, 610 Medical sciences, Temozolomide, Cell Line, Tumor [MeSH], Aged [MeSH], Proto-Oncogene Proteins B-raf/genetics [MeSH], Anthracyclines/pharmacology [MeSH], Antineoplastic Agents/pharmacology [MeSH], Glioblastoma/metabolism [MeSH], Targeted chemotherapy, Proto-Oncogene Proteins B-raf/metabolism [MeSH], Glioblastoma/drug therapy [MeSH], Preclinical Studies, Class Ia Phosphatidylinositol 3-Kinase/metabolism [MeSH], Glioblastoma/genetics [MeSH], Temozolomide/pharmacology [MeSH], Mutation [MeSH], Brain Neoplasms/genetics [MeSH], Drug repurposing, Class Ia Phosphatidylinositol 3-Kinase/genetics [MeSH], Humans [MeSH], Anthracyclines/therapeutic use [MeSH], Precision medicine, Drug Repositioning [MeSH], Antineoplastic Agents/therapeutic use [MeSH], Temozolomide/therapeutic use [MeSH], Transcriptome [MeSH], Genotype [MeSH], Brain Neoplasms/drug therapy [MeSH], Virtual drug screening, Brain Neoplasms/metabolism [MeSH], Humans, Anthracyclines, Aged, ddc:610, 0303 health sciences, Brain Neoplasms, Drug Repositioning, 3. Good health, Class Ia Phosphatidylinositol 3-Kinase, Mutation, ddc:570, Glioblastoma, Transcriptome, 570 Biowissenschaften

Popis súboru: pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s10637-020-01037-7.pdf
https://pubmed.ncbi.nlm.nih.gov/33313992
https://pubmed.ncbi.nlm.nih.gov/33313992/
https://paperity.org/p/259778698/drug-repurposing-using-transcriptome-sequencing-and-virtual-drug-screening-in-a-patient
https://link.springer.com/article/10.1007/s10637-020-01037-7
https://link.springer.com/content/pdf/10.1007/s10637-020-01037-7.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068653/
https://europepmc.org/article/MED/33313992
https://repository.publisso.de/resource/frl:6468396

High expression of estrogen receptor alpha and aromatase in glial tumor cells is associated with gender-independent survival benefits in glioblastoma patients

Autori: Hönikl, Lisa Stefanie Lämmer, Friederike Gempt, Jens a ďalší

Zdroj: J Neurooncol

Predmety: Adult, Aged, 80 and over, Male, 0301 basic medicine, 2. Zero hunger, Sex Characteristics, TMZ, Female [MeSH], Cell Line, Tumor [MeSH], Aged, 80 and over [MeSH], Aged [MeSH], Adult [MeSH], Estrogen receptor alpha, Kaplan-Meier Estimate [MeSH], Humans [MeSH], Laboratory Investigation, Glioblastoma multiforme, Middle Aged [MeSH], Glioblastoma/metabolism [MeSH], Neuroglia/metabolism [MeSH], 17β-estradiol, Aromatase/metabolism [MeSH], Survival, Male [MeSH], Aromatase, Estrogen Receptor alpha/metabolism [MeSH], Sex Characteristics [MeSH], Brain Neoplasms/metabolism [MeSH], Combined therapy in vitro, Brain Neoplasms, Estrogen Receptor alpha, Kaplan-Meier Estimate, Middle Aged, ddc, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Humans, Female, Glioblastoma, Neuroglia, Aged

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s11060-020-03467-y.pdf
https://pubmed.ncbi.nlm.nih.gov/32240464
https://pubmed.ncbi.nlm.nih.gov/32240464/
https://link.springer.com/content/pdf/10.1007/s11060-020-03467-y.pdf
https://link.springer.com/article/10.1007/s11060-020-03467-y
https://www.ncbi.nlm.nih.gov/pubmed/32240464
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256026
https://repository.publisso.de/resource/frl:6470816
https://mediatum.ub.tum.de/doc/1547455/document.pdf