Suchergebnisse - "Ghrelin"

Effects of Ghrelin Hormone on Alzheimer's and Parkinson's Disease: A Systematic Review of the Existing Literature.

Autoren: Abdulazeez Y Utami RN Al-Jamal KT et al.

Quelle: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Nov 05; Vol. 16 (21), pp. 4159-4171. Date of Electronic Publication: 2025 Oct 23.

Publikationsart: Journal Article; Systematic Review; Review

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/metabolism , Ghrelin*/therapeutic use , Ghrelin*/pharmacology , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Parkinson Disease*/drug therapy , Parkinson Disease*/metabolism, Humans ; Animals ; Receptors, Ghrelin/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use

Temporal control of eating and body weight by GHSR-expressing suprachiasmatic nucleus neurons.

Autoren: Singh O Sheybani-Deloui S Kulkarni S et al.

Quelle: Cell reports [Cell Rep] 2025 Sep 23; Vol. 44 (9), pp. 116213. Date of Electronic Publication: 2025 Sep 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Ghrelin*/metabolism , Receptors, Ghrelin*/genetics , Body Weight*/physiology , Eating*/physiology , Suprachiasmatic Nucleus Neurons*/metabolism , Suprachiasmatic Nucleus*/metabolism , Neurons*/metabolism, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Ghrelin/metabolism ; Ghrelin/pharmacology ; Arcuate Nucleus of Hypothalamus/metabolism ; Feeding Behavior

Bridging the gap: Ghrelin and the female stress response to acute non-discriminatory social defeat.

Autoren: MacAulay B Smith A Abizaid A

Quelle: Neuroscience [Neuroscience] 2025 Aug 30; Vol. 582, pp. 32-40. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

MeSH-Schlagworte: Stress, Psychological*/metabolism , Stress, Psychological*/blood , Ghrelin*/blood , Ghrelin*/metabolism , Social Defeat*, Animals ; Female ; Male ; Mice, Knockout ; Receptors, Ghrelin/genetics ; Receptors, Ghrelin/metabolism ; Receptors, Ghrelin/deficiency ; Corticosterone/blood ; Mice ; Paraventricular Hypothalamic Nucleus/metabolism

Regulation of Ghrelin Production and Food Intake by Gastric Adenylyl Cyclase Type 8.

Autoren: Wu S Deng H Yu R et al.

Quelle: Journal of cellular physiology [J Cell Physiol] 2025 Aug; Vol. 240 (8), pp. e70087.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

MeSH-Schlagworte: Adenylyl Cyclases*/metabolism , Adenylyl Cyclases*/genetics , Ghrelin*/metabolism , Ghrelin*/genetics , Ghrelin*/biosynthesis , Eating*/drug effects , Eating*/physiology , Gastric Mucosa*/metabolism , Gastric Mucosa*/enzymology , Gastric Mucosa*/drug effects, Animals ; Cyclic AMP/metabolism ; Mice, Knockout ; Mice ; Signal Transduction ; Male ; Cyclic AMP-Dependent Protein Kinases/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Mice, Inbred C57BL ; Diet, High-Fat ; Colforsin/pharmacology ; Receptors, Ghrelin/metabolism

Altered circadian pattern of activity in a chronic activity-based anorexia nervosa-like female mouse model deficient for GHSR.

Autoren: Mattioni J Duriez P Aïdat S et al.

Quelle: Psychoneuroendocrinology [Psychoneuroendocrinology] 2025 Jul; Vol. 177, pp. 107453. Date of Electronic Publication: 2025 Apr 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 7612148 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3360 (Electronic) Linking ISSN: 03064530 NLM ISO Abbreviation: Psychoneuroendocrinology Subsets: MEDLINE

MeSH-Schlagworte: Anorexia Nervosa*/physiopathology , Anorexia Nervosa*/metabolism , Anorexia Nervosa*/genetics , Circadian Rhythm*/physiology , Circadian Rhythm*/genetics , Receptors, Ghrelin*/genetics , Receptors, Ghrelin*/deficiency , Receptors, Ghrelin*/metabolism , Receptors, Ghrelin*/physiology, Animals ; Female ; Mice ; Disease Models, Animal ; Mice, Knockout ; Humans ; Ghrelin/blood ; Ghrelin/metabolism ; Adult ; Mice, Inbred C57BL ; Bulimia Nervosa/physiopathology ; Bulimia Nervosa/metabolism

Ghrelin's potential as a therapeutic target for chronic inflammatory diseases: evidence from human endometrial stromal cells.

Autoren: Dong W Mu H Jia F et al.

Quelle: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Sep 01; Vol. 16, pp. 1587490. Date of Electronic Publication: 2025 Sep 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/pharmacology , Stromal Cells*/drug effects , Stromal Cells*/metabolism , Stromal Cells*/pathology , Endometrium*/metabolism , Endometrium*/drug effects , Endometrium*/pathology , Endometrium*/cytology , Inflammation*/drug therapy , Inflammation*/metabolism , Inflammation*/pathology, Humans ; Female ; Receptors, Ghrelin/metabolism ; Cell Survival/drug effects ; Cytokines/metabolism ; Cell Proliferation/drug effects ; Cells, Cultured ; Chronic Disease

Ghrelin-induced neuronal NPY promotes brain metastasis in lung cancer patients with low BMI.

Autoren: Tyagi A Wu SY Kim JW et al.

Quelle: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5608. Date of Electronic Publication: 2025 Jul 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Lung Neoplasms*/pathology , Lung Neoplasms*/metabolism , Ghrelin*/metabolism , Ghrelin*/blood , Neuropeptide Y*/metabolism , Neuropeptide Y*/genetics , Brain Neoplasms*/secondary , Brain Neoplasms*/metabolism , Neurons*/metabolism, Humans ; Body Mass Index ; Male ; Female ; Animals ; Middle Aged ; Mice ; Obesity/metabolism ; Obesity/complications ; Cell Line, Tumor ; Receptors, Ghrelin/metabolism ; Receptors, Neuropeptide Y/metabolism ; Signal Transduction ; Aged

Growth Hormone Secretagogue Receptor (GHSR) Is Elevated in Myocardial Tissues of DMD mdx:utrn^-/- Mice, and Correlates Strongly with Inflammatory Markers, and Negatively with Cardiac Function.

Autoren: Naghibosadat M McClennan A Egiian M et al.

Quelle: Cells [Cells] 2025 Jul 01; Vol. 14 (13). Date of Electronic Publication: 2025 Jul 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Ghrelin*/metabolism , Muscular Dystrophy, Duchenne*/metabolism , Muscular Dystrophy, Duchenne*/physiopathology , Muscular Dystrophy, Duchenne*/pathology , Muscular Dystrophy, Duchenne*/complications , Myocardium*/metabolism , Myocardium*/pathology , Inflammation*/metabolism , Inflammation*/pathology , Utrophin*/metabolism , Utrophin*/deficiency , Utrophin*/genetics, Animals ; Mice, Inbred mdx ; Mice ; Biomarkers/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Ghrelin/metabolism ; Cardiomyopathy, Dilated/metabolism ; Cardiomyopathy, Dilated/pathology ; Disease Models, Animal

Evidence for independent actions of the CRF and ghrelin systems in binge-like alcohol drinking in mice.

Autoren: Richardson RS Kryszak LA Vendruscolo JCM et al.

Quelle: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2025 Apr 02; Vol. 138, pp. 111341. Date of Electronic Publication: 2025 Mar 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 8211617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4216 (Electronic) Linking ISSN: 02785846 NLM ISO Abbreviation: Prog Neuropsychopharmacol Biol Psychiatry Subsets: MEDLINE

MeSH-Schlagworte: Binge Drinking*/metabolism , Binge Drinking*/blood , Binge Drinking*/drug therapy , Corticotropin-Releasing Hormone*/metabolism , Corticotropin-Releasing Hormone*/pharmacology , CRF Receptor, Type 1*/antagonists & inhibitors , Ghrelin*/blood , Ghrelin*/metabolism, Animals ; Female ; Male ; Mice ; Ethanol ; Mice, Inbred C57BL ; Peptide Fragments/pharmacology ; Receptors, Corticotropin-Releasing Hormone/antagonists & inhibitors ; Receptors, Corticotropin-Releasing Hormone/metabolism ; Receptors, Ghrelin/antagonists & inhibitors ; Receptors, Ghrelin/metabolism ; Pyrimidines

Physiological roles of ghrelin in the regulation of gastrointestinal motility in vertebrates.

Autoren: Zhang S Kaiya H Kitazawa T

Quelle: General and comparative endocrinology [Gen Comp Endocrinol] 2025 Apr; Vol. 365, pp. 114698. Date of Electronic Publication: 2025 Feb 28.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0370735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6840 (Electronic) Linking ISSN: 00166480 NLM ISO Abbreviation: Gen Comp Endocrinol Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/physiology , Ghrelin*/metabolism , Gastrointestinal Motility*/physiology , Vertebrates*/physiology, Animals ; Humans ; Receptors, Ghrelin/metabolism

The role of leptin and ghrelin in the regulation of appetite in obesity.

Autoren: Skoracka K Hryhorowicz S Schulz P et al.

Quelle: Peptides [Peptides] 2025 Apr; Vol. 186, pp. 171367. Date of Electronic Publication: 2025 Feb 19.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/metabolism , Ghrelin*/genetics , Leptin*/metabolism , Leptin*/genetics , Obesity*/metabolism , Obesity*/physiopathology , Obesity*/genetics , Appetite*/physiology , Appetite Regulation*, Humans ; Animals ; Energy Metabolism ; Signal Transduction ; Receptors, Ghrelin/metabolism ; Eating

Mini-ghrelins: Functional Characterization of N-terminal Peptides Derived From Ghrelin Proteolysis in Male Samples.

Autoren: Fernandez G Fittipaldi A Lufrano D et al.

Quelle: Endocrinology [Endocrinology] 2025 Jun 10; Vol. 166 (8).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/metabolism , Ghrelin*/blood , Ghrelin*/chemistry , Peptide Fragments*/metabolism , Peptide Fragments*/blood, Animals ; Male ; Humans ; Mice ; Proteolysis ; Rats ; Receptors, Ghrelin/metabolism ; Mice, Inbred C57BL ; Neurons/metabolism

Meal-feeding promotes skeletal growth by ghrelin-dependent enhancement of growth hormone rhythmicity.

Autoren: Hornsby AK Brown RC Tilston TW et al.

Quelle: The Journal of clinical investigation [J Clin Invest] 2025 Apr 01; Vol. 135 (12). Date of Electronic Publication: 2025 Apr 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/blood , Ghrelin*/physiology , Human Growth Hormone*/blood , Meals* , Bone Development*/physiology , Feeding Behavior*/physiology , Growth Hormone*/metabolism , Growth Hormone*/blood, Animals ; Humans ; Male ; Rats ; Adult ; Receptors, Ghrelin/metabolism ; Rats, Sprague-Dawley

Ghrelin-LEAP2 interactions along the stomach-liver axis.

Autoren: Sakai K Nakazato Y Shiimura Y et al.

Quelle: Endocrine journal [Endocr J] 2025 Apr 01; Vol. 72 (4), pp. 341-353. Date of Electronic Publication: 2024 Dec 27.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Japan Endocrine Society Country of Publication: Japan NLM ID: 9313485 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1348-4540 (Electronic) Linking ISSN: 09188959 NLM ISO Abbreviation: Endocr J Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/metabolism , Liver*/metabolism , Gastric Mucosa*/metabolism , Stomach*/physiology, Animals ; Humans ; Receptors, Ghrelin/metabolism ; Obesity/metabolism ; Mice ; Eating ; Blood Proteins ; Antimicrobial Cationic Peptides

Regulatory Effects of Copper on Ghrelin Secretion in Rat Fundic Glands.

Autoren: Sun R Wang Z Li M et al.

Quelle: Journal of animal physiology and animal nutrition [J Anim Physiol Anim Nutr (Berl)] 2025 Mar; Vol. 109 (2), pp. 521-532. Date of Electronic Publication: 2024 Nov 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: Germany NLM ID: 101126979 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0396 (Electronic) Linking ISSN: 09312439 NLM ISO Abbreviation: J Anim Physiol Anim Nutr (Berl) Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/metabolism , Ghrelin*/genetics , Copper*/pharmacology , Copper*/administration & dosage , Gastric Fundus*/metabolism , Gastric Fundus*/drug effects , Gastric Mucosa*/metabolism, Animals ; Rats, Sprague-Dawley ; Rats ; Male ; Gene Expression Regulation/drug effects ; Animal Feed/analysis ; Receptors, Ghrelin/metabolism ; Receptors, Ghrelin/genetics ; Animal Nutritional Physiological Phenomena ; Dietary Supplements

Ghrelin Recruits the Endocannabinoid System to Modulate Food Reward.

Autoren: Edwards A DeSante S Spencer CD et al.

Quelle: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Feb 26; Vol. 45 (9). Date of Electronic Publication: 2025 Feb 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/pharmacology , Ghrelin*/physiology , Ghrelin*/metabolism , Endocannabinoids*/metabolism , Reward* , Feeding Behavior*/physiology , Feeding Behavior*/drug effects, Animals ; Male ; Female ; Mice ; Rats ; Ventral Tegmental Area/metabolism ; Ventral Tegmental Area/drug effects ; Ventral Tegmental Area/physiology ; Receptors, Ghrelin/genetics ; Receptors, Ghrelin/metabolism ; Receptor, Cannabinoid, CB1/metabolism ; Receptor, Cannabinoid, CB1/genetics ; Mice, Inbred C57BL ; Rats, Sprague-Dawley ; Mice, Knockout ; Glycerides/metabolism ; Dopaminergic Neurons/drug effects ; Dopaminergic Neurons/metabolism

Midbrain ghrelin receptor signalling regulates binge drinking in a sex specific manner.

Autoren: Pearl AJ Maddern XJ Pinares-Garcia P et al.

Quelle: Nature communications [Nat Commun] 2025 Mar 15; Vol. 16 (1), pp. 2568. Date of Electronic Publication: 2025 Mar 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Ghrelin*/metabolism , Receptors, Ghrelin*/genetics , Receptors, Ghrelin*/antagonists & inhibitors , Receptors, Ghrelin*/agonists , Binge Drinking*/metabolism , Binge Drinking*/genetics , Mesencephalon*/metabolism, Animals ; Female ; Male ; Ghrelin/metabolism ; Ghrelin/pharmacology ; Signal Transduction ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Neurons/drug effects ; Sex Characteristics ; Ventral Tegmental Area/metabolism

Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice.

Autoren: Poelman R Le May MV Schéle E et al.

Quelle: Endocrinology [Endocrinology] 2025 Feb 05; Vol. 166 (3).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/administration & dosage , Ghrelin*/metabolism , Ghrelin*/pharmacology , Signal Transduction*/drug effects , Oligopeptides*/administration & dosage , Oligopeptides*/pharmacology , Brain*/metabolism , Brain*/drug effects, Animals ; Administration, Intranasal ; Male ; Mice ; Eating/drug effects ; Receptors, Ghrelin/metabolism ; Arcuate Nucleus of Hypothalamus/metabolism ; Arcuate Nucleus of Hypothalamus/drug effects ; Mice, Inbred C57BL ; Neurons/metabolism ; Neurons/drug effects

G protein peptidomimetics reveal allosteric effects and stepwise interactions in ghrelin receptor-G protein coupling.

Autoren: Mannes M Martin C Damian M et al.

Quelle: Science signaling [Sci Signal] 2025 Feb 04; Vol. 18 (872), pp. eado7692. Date of Electronic Publication: 2025 Feb 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Ghrelin*/metabolism , Receptors, Ghrelin*/chemistry , Receptors, Ghrelin*/genetics , Peptidomimetics*/chemistry , Peptidomimetics*/metabolism , Peptidomimetics*/pharmacology , GTP-Binding Proteins*/metabolism , GTP-Binding Proteins*/chemistry, Allosteric Regulation ; Humans ; Signal Transduction ; Protein Binding ; HEK293 Cells ; Animals ; Ghrelin/metabolism ; Ghrelin/chemistry ; Protein Conformation

Ghrelin promotes chronic diabetic wound healing by regulating keratinocyte proliferation and migration through the ERK1/2 pathway.

Autoren: Zhang Y Chen Y Li K et al.

Quelle: Peptides [Peptides] 2025 Feb; Vol. 184, pp. 171350. Date of Electronic Publication: 2025 Jan 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE

MeSH-Schlagworte: Ghrelin*/pharmacology , Keratinocytes*/drug effects , Keratinocytes*/metabolism , Wound Healing*/drug effects , MAP Kinase Signaling System*/drug effects , Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/pathology, Animals ; Cell Proliferation/drug effects ; Cell Movement/drug effects ; Rats ; Receptors, Ghrelin/metabolism ; Receptors, Ghrelin/genetics ; Male ; Rats, Sprague-Dawley ; Humans