Suchergebnisse - "Germ Cells"

TET knockout cells transit between pluripotent states and exhibit precocious germline entry.

Autoren: Pantier R Barbieri E Gonzalez Brito S et al.

Quelle: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (23), pp. 7060-7089. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

MeSH-Schlagworte: DNA-Binding Proteins*/genetics , DNA-Binding Proteins*/metabolism , Proto-Oncogene Proteins*/genetics , Proto-Oncogene Proteins*/metabolism , Cell Differentiation* , Germ Cells*/cytology , Germ Cells*/metabolism , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/metabolism , Mouse Embryonic Stem Cells*/cytology , Mouse Embryonic Stem Cells*/metabolism, Animals ; Mice ; Dioxygenases/genetics ; Gene Knockout Techniques ; Mice, Knockout ; Gene Expression Regulation, Developmental

Mechanical contribution of germ cell specification in Arabidopsis anthers.

Autoren: Liu C Shi H Han Y et al.

Quelle: Science advances [Sci Adv] 2025 Oct 24; Vol. 11 (43), pp. eady7872. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

MeSH-Schlagworte: Arabidopsis*/genetics , Arabidopsis*/growth & development , Arabidopsis*/cytology , Arabidopsis*/metabolism , Flowers*/growth & development , Flowers*/cytology , Flowers*/genetics , Flowers*/metabolism , Germ Cells, Plant*/metabolism , Germ Cells, Plant*/cytology , Germ Cells*/cytology , Germ Cells*/metabolism, Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Gene Expression Regulation, Plant ; Biomechanical Phenomena ; Cell Wall/metabolism

A primordial germ cell-like-cell platform enables CRISPRi screen for epigenetic fertility modifiers.

Autoren: Li L Gao J Yi D et al.

Quelle: EMBO reports [EMBO Rep] 2025 Dec; Vol. 26 (23), pp. 6044-6078. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH-Schlagworte: Germ Cells*/metabolism , Germ Cells*/cytology , Epigenesis, Genetic* , Fertility*/genetics , CRISPR-Cas Systems*, Animals ; Mice ; Male ; Positive Regulatory Domain I-Binding Factor 1/genetics ; Positive Regulatory Domain I-Binding Factor 1/metabolism ; Cell Differentiation/genetics ; Nanog Homeobox Protein/genetics ; Nanog Homeobox Protein/metabolism ; Transcription Factor AP-2/genetics ; Transcription Factor AP-2/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Female ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; RNA-Binding Proteins/genetics ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism

A face-off between Smaug and Caspar modulates primordial germ cell count and identity in Drosophila embryos.

Autoren: Deshpande G Das S Roy AE et al.

Quelle: Fly [Fly (Austin)] 2025 Dec; Vol. 19 (1), pp. 2438473. Date of Electronic Publication: 2024 Dec 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101470897 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6942 (Electronic) Linking ISSN: 19336934 NLM ISO Abbreviation: Fly (Austin) Subsets: MEDLINE

MeSH-Schlagworte: Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Germ Cells*/metabolism , Germ Cells*/cytology , Drosophila melanogaster*/metabolism , Drosophila melanogaster*/embryology, Animals ; Female ; Embryo, Nonmammalian/metabolism ; Embryo, Nonmammalian/cytology ; Centrosome/metabolism ; Male ; Cell Adhesion Molecules, Neuronal

Regulation of Germ Cell Apoptosis by Innate Immune Pathways in Caenorhabditis elegans Exposed to Ionizing Radiation.

Autoren: Li X Li K Zhao M et al.

Quelle: Radiation research [Radiat Res] 2025 Dec 01; Vol. 204 (6), pp. 635-654.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Radiation Research Society Country of Publication: United States NLM ID: 0401245 Publication Model: Print Cited Medium: Internet ISSN: 1938-5404 (Electronic) Linking ISSN: 00337587 NLM ISO Abbreviation: Radiat Res Subsets: MEDLINE

MeSH-Schlagworte: Caenorhabditis elegans*/radiation effects , Caenorhabditis elegans*/immunology , Caenorhabditis elegans*/cytology , Caenorhabditis elegans*/genetics , Immunity, Innate*/radiation effects , Immunity, Innate*/genetics , Apoptosis*/radiation effects , Apoptosis*/genetics , Germ Cells*/radiation effects , Germ Cells*/cytology , Germ Cells*/immunology , Radiation, Ionizing*, Animals ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Mutation ; Gene Expression Regulation/radiation effects

Germ granule-mediated mRNA storage and translational control.

Autoren: Pham-Bui HA Lee M

Quelle: RNA biology [RNA Biol] 2025 Dec; Vol. 22 (1), pp. 1-11. Date of Electronic Publication: 2025 Feb 06.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

MeSH-Schlagworte: Germ Cells*/metabolism , Cytoplasmic Granules*/metabolism , Cytoplasmic Granules*/genetics , Protein Biosynthesis* , RNA, Messenger*/metabolism , RNA, Messenger*/genetics, Animals ; Humans ; Gene Expression Regulation, Developmental

Promoting mBMMSC differentiation into late-stage germ-like cells through retinoic acid, fibrin-coated titanium nanotubes, and ultraviolet radiation.

Autoren: Shams A Ebrahimi S Shams MA et al.

Quelle: Histochemistry and cell biology [Histochem Cell Biol] 2025 Nov 28; Vol. 163 (1), pp. 110. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Germany NLM ID: 9506663 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-119X (Electronic) Linking ISSN: 09486143 NLM ISO Abbreviation: Histochem Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/drug effects , Mesenchymal Stem Cells*/metabolism , Fibrin*/chemistry , Fibrin*/pharmacology , Titanium*/chemistry , Titanium*/pharmacology , Cell Differentiation*/drug effects , Ultraviolet Rays* , Tretinoin*/pharmacology , Tretinoin*/chemistry , Nanotubes*/chemistry , Germ Cells*/cytology , Germ Cells*/drug effects, Animals ; Mice ; Cells, Cultured ; Male ; Female

AAV2/9 Enables Superior Germ Cell Transduction in Mouse Testes.

Autoren: Wu B Guo Y Li R

Quelle: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2025 Nov 27; Vol. 30 (11), pp. 46354.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE

MeSH-Schlagworte: Dependovirus*/genetics , Testis*/metabolism , Testis*/cytology , Transduction, Genetic*/methods , Genetic Vectors*/genetics , Germ Cells*/metabolism, Animals ; Male ; Mice ; Genetic Therapy/methods ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Capsid Proteins/genetics ; Mice, Inbred C57BL ; Humans ; Gene Transfer Techniques

Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants.

Autoren: Jaszczak RG Zussman JW Wagner DE et al.

Quelle: ELife [Elife] 2025 Nov 19; Vol. 14. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Cell Movement* , Germ Cells*/physiology , Germ Cells*/metabolism , Nodal Protein*/metabolism , Nodal Protein*/genetics , Wnt Signaling Pathway* , Left-Right Determination Factors*/metabolism , Left-Right Determination Factors*/genetics, Animals ; Mice ; Signal Transduction ; Gene Expression Regulation, Developmental

Production of offspring via the transplantation of frozen germ cells from Tokyo bitterling, a fish on the brink of extinction.

Autoren: Yamakawa K Kawaguchi K Yoshizaki G

Quelle: Scientific reports [Sci Rep] 2025 Nov 19; Vol. 15 (1), pp. 40759. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Cryopreservation*/methods , Germ Cells*/transplantation , Germ Cells*/cytology , Extinction, Biological* , Fishes*, Animals ; Male ; Female ; Endangered Species ; Spermatozoa/transplantation

Early female germline development in Xenopus laevis : Stem cells, nurse cells, and germline cysts.

Autoren: Davidian A Spradling AC

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 18; Vol. 122 (46), pp. e2522343122. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Xenopus laevis*/genetics , Oocytes*/cytology , Oocytes*/metabolism , Stem Cells*/cytology , Stem Cells*/metabolism , Oogenesis*/physiology , Germ Cells*/cytology , Germ Cells*/metabolism, Animals ; Female ; Cell Differentiation ; Ovary/cytology ; Single-Cell Analysis

Collagen processing is essential for germ cell identity.

Autoren: Roman S Oulhen N Reyes G et al.

Quelle: Biology open [Biol Open] 2025 Nov 15; Vol. 14 (11). Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101578018 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2046-6390 (Electronic) Linking ISSN: 20466390 NLM ISO Abbreviation: Biol Open Subsets: MEDLINE

MeSH-Schlagworte: Germ Cells*/metabolism , Germ Cells*/cytology , Collagen*/metabolism , Protein Processing, Post-Translational*, Animals ; Protein-Lysine 6-Oxidase/metabolism ; Protein-Lysine 6-Oxidase/antagonists & inhibitors ; Protein-Lysine 6-Oxidase/genetics ; Extracellular Matrix/metabolism ; Sea Urchins/metabolism ; Sea Urchins/embryology ; Embryonic Development

Interplay of EGFR, JNK, and ROS signaling in soma-germline communication in the Drosophila testis.

Autoren: Alvarez M Papagiannouli F

Quelle: Stem cell reports [Stem Cell Reports] 2025 Nov 11; Vol. 20 (11), pp. 102676. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

MeSH-Schlagworte: Testis*/metabolism , Testis*/cytology , ErbB Receptors*/metabolism , ErbB Receptors*/genetics , Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Reactive Oxygen Species*/metabolism , Germ Cells*/metabolism , Germ Cells*/cytology , Receptors, Invertebrate Peptide*/metabolism , Receptors, Invertebrate Peptide*/genetics , Cell Communication* , Drosophila melanogaster*/metabolism , MAP Kinase Signaling System*, Animals ; Male ; Signal Transduction ; Drosophila/metabolism

Hypothesis: Germline rejuvenation during meiosis underlies animal oogenesis.

Autoren: A S M P A D et al.

Quelle: Developmental biology [Dev Biol] 2025 Nov; Vol. 527, pp. 65-76. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372762 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-564X (Electronic) Linking ISSN: 00121606 NLM ISO Abbreviation: Dev Biol Subsets: MEDLINE

MeSH-Schlagworte: Germ Cells*/physiology , Germ Cells*/cytology , Meiosis*/physiology , Oogenesis*/physiology, Animals ; Female ; Biological Evolution ; Oocytes/cytology ; Oocytes/physiology

Germ cell formation and reproduction in tunicates.

Autoren: Sasakura Y Sunanaga T Onuma TA et al.

Quelle: Developmental biology [Dev Biol] 2025 Nov; Vol. 527, pp. 226-249. Date of Electronic Publication: 2025 Aug 18.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372762 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-564X (Electronic) Linking ISSN: 00121606 NLM ISO Abbreviation: Dev Biol Subsets: MEDLINE

MeSH-Schlagworte: Urochordata*/physiology , Urochordata*/cytology , Urochordata*/genetics , Urochordata*/embryology , Germ Cells*/cytology , Germ Cells*/physiology, Animals ; Reproduction/physiology ; Gene Expression Regulation, Developmental

Avian primordial germ cell migration: History, mechanisms, applications, and unanswered questions.

Autoren: Morimoto M Saito D

Quelle: Protein expression and purification [Protein Expr Purif] 2025 Nov; Vol. 235, pp. 106788. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article; Review; Historical Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9101496 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0279 (Electronic) Linking ISSN: 10465928 NLM ISO Abbreviation: Protein Expr Purif Subsets: MEDLINE

MeSH-Schlagworte: Cell Movement* , Germ Cells*/cytology , Germ Cells*/metabolism, Animals ; Chick Embryo ; History, 20th Century ; Chickens

The Somatic Impact on Inheritance and the Germline Control of the Soma.

Autoren: Ishikawa S Schumacher B

Quelle: Annual review of genetics [Annu Rev Genet] 2025 Nov; Vol. 59 (1), pp. 91-117. Date of Electronic Publication: 2025 Jul 16.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Annual Reviews Country of Publication: United States NLM ID: 0117605 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-2948 (Electronic) Linking ISSN: 00664197 NLM ISO Abbreviation: Annu Rev Genet Subsets: MEDLINE

MeSH-Schlagworte: Germ Cells*/metabolism , Germ Cells*/physiology , Epigenesis, Genetic* , Inheritance Patterns*/genetics, Humans ; Animals ; Heredity ; Reproduction/genetics

Primordial germ cell specification and early developmental cell states in Pacific oyster.

Autoren: Gavery MR Vandepas LE Saunders LM et al.

Quelle: BMC genomics [BMC Genomics] 2025 Oct 23; Vol. 26 (1), pp. 951. Date of Electronic Publication: 2025 Oct 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

MeSH-Schlagworte: Germ Cells*/cytology , Germ Cells*/metabolism , Crassostrea*/genetics , Crassostrea*/embryology , Crassostrea*/cytology, Animals ; Gene Expression Regulation, Developmental ; Transcriptome ; Cell Differentiation/genetics ; Single-Cell Analysis ; Gene Expression Profiling

Propiconazole-Induced Testis Damage and MAPK-Mediated Apoptosis and Autophagy in Germ Cells.

Autoren: Lee WY Lee R Sim HW et al.

Quelle: Cells [Cells] 2025 Oct 17; Vol. 14 (20). Date of Electronic Publication: 2025 Oct 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/drug effects , Apoptosis*/drug effects , Testis*/drug effects , Testis*/pathology , Triazoles*/toxicity , Triazoles*/pharmacology , Germ Cells*/drug effects , Germ Cells*/metabolism , MAP Kinase Signaling System*/drug effects, Male ; Animals ; Mice ; Sperm Motility/drug effects ; Spermatogonia/drug effects ; Spermatogonia/metabolism

Non-autonomy of age-related morphological changes in the C. elegans germline stem cell niche.

Autoren: Gupta N Sinks M Hubbard EJA

Quelle: Development (Cambridge, England) [Development] 2025 Oct 15; Vol. 152 (20). Date of Electronic Publication: 2025 Oct 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH-Schlagworte: Caenorhabditis elegans*/cytology , Caenorhabditis elegans*/genetics , Caenorhabditis elegans*/physiology , Caenorhabditis elegans*/metabolism , Germ Cells*/cytology , Germ Cells*/metabolism , Stem Cell Niche*/physiology , Aging*/physiology , Stem Cells*/cytology, Animals ; Caenorhabditis elegans Proteins/metabolism ; Caenorhabditis elegans Proteins/genetics ; Forkhead Transcription Factors/metabolism ; Forkhead Transcription Factors/genetics ; Cell Differentiation ; Receptor, Insulin/metabolism ; Receptor, Insulin/genetics ; Mutation