Search Results - "Gene Expression Regulation, Neoplastic"

Red single wavelength emitting up-conversion nanoparticles modulate cellular dynamics and gene expression in T24 bladder cancer cells.

Authors: Alsayeh AR Abdelrazek EM Oraby AH et al.

Source: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42539. Date of Electronic Publication: 2025 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Urinary Bladder Neoplasms*/genetics , Urinary Bladder Neoplasms*/pathology , Urinary Bladder Neoplasms*/metabolism , Nanoparticles*/chemistry , Gene Expression Regulation, Neoplastic*/drug effects , Gene Expression Regulation, Neoplastic*/radiation effects, Humans ; Cell Line, Tumor ; Reactive Oxygen Species/metabolism ; Apoptosis/drug effects ; Apoptosis/radiation effects ; Oxidative Stress/drug effects

Genes Associated with Apoptosis in an Experimental Breast Cancer Model.

Authors: Calaf GM Crispin LA

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 07; Vol. 26 (19). Date of Electronic Publication: 2025 Oct 07.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Apoptosis*/genetics , Apoptosis*/radiation effects , Breast Neoplasms*/genetics , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Gene Expression Regulation, Neoplastic*/drug effects , Gene Expression Regulation, Neoplastic*/radiation effects, Humans ; Female ; Cell Line, Tumor ; Gene Expression Profiling ; Receptors, Estrogen/metabolism ; Receptors, Estrogen/genetics

GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.

Authors: Dong C Gao Z Li X

Source: Journal of translational medicine [J Transl Med] 2025 Dec 02; Vol. 23 (1), pp. 1369. Date of Electronic Publication: 2025 Dec 02.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH Terms: Kruppel-Like Transcription Factors*/metabolism , Kruppel-Like Transcription Factors*/genetics , Osteosarcoma*/genetics , Osteosarcoma*/pathology , Gene Expression Regulation, Neoplastic* , Disease Progression* , Glutathione Peroxidase*/genetics , Glutathione Peroxidase*/metabolism , Transcription, Genetic* , Bone Neoplasms*/pathology , Bone Neoplasms*/genetics, Humans ; Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Movement/genetics ; Neoplasm Invasiveness ; Mice, Nude ; Mice ; Male ; Female ; Epithelial-Mesenchymal Transition/genetics ; Protein Binding

Targeting MCM6 Enhances Melphalan Chemosensitivity in Retinoblastoma by Modulating DNA Damage Response.

Authors: Wang M Tang J Li J et al.

Source: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Dec 01; Vol. 66 (15), pp. 14.

Publication Type: Journal Article

Journal Info: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH Terms: Retinoblastoma*/drug therapy , Retinoblastoma*/genetics , Retinoblastoma*/metabolism , Retinoblastoma*/pathology , Melphalan*/pharmacology , Melphalan*/therapeutic use , Antineoplastic Agents, Alkylating*/pharmacology , Antineoplastic Agents, Alkylating*/therapeutic use , Retinal Neoplasms*/drug therapy , Retinal Neoplasms*/genetics , Retinal Neoplasms*/metabolism , Retinal Neoplasms*/pathology , DNA Damage* , Minichromosome Maintenance Complex Component 6*/genetics , Minichromosome Maintenance Complex Component 6*/biosynthesis , Minichromosome Maintenance Complex Component 6*/metabolism , Gene Expression Regulation, Neoplastic*, Humans ; Animals ; Mice ; Cell Proliferation ; Xenograft Model Antitumor Assays ; Cell Line, Tumor ; Gene Knockdown Techniques ; Cell Cycle ; Drug Resistance, Neoplasm

METTL14 Regulates the Expression of Genes Related to Interferon, Interleukin and MHC Class I in Nasopharyngeal Carcinoma Cells.

Authors: Zhou Z Wang J Shen L et al.

Source: Cancer medicine [Cancer Med] 2025 Dec; Vol. 14 (23), pp. e71371.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

MeSH Terms: Nasopharyngeal Carcinoma*/genetics , Nasopharyngeal Carcinoma*/metabolism , Nasopharyngeal Carcinoma*/pathology , Gene Expression Regulation, Neoplastic* , Methyltransferases*/genetics , Methyltransferases*/metabolism , Nasopharyngeal Neoplasms*/genetics , Nasopharyngeal Neoplasms*/metabolism , Nasopharyngeal Neoplasms*/pathology , Interferons*/genetics , Interferons*/metabolism , Interleukins*/genetics , Interleukins*/metabolism , Genes, MHC Class I* , Histocompatibility Antigens Class I*/genetics, Humans ; Cell Line, Tumor

Prognostic signature based on mitochondria- and angiogenesis-related genes associated with immune microenvironment of multiple myeloma.

Authors: Zhang D Xing Y Liu L et al.

Source: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2456649. Date of Electronic Publication: 2025 Jan 28.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH Terms: Multiple Myeloma*/genetics , Multiple Myeloma*/immunology , Multiple Myeloma*/pathology , Multiple Myeloma*/mortality , Tumor Microenvironment*/genetics , Tumor Microenvironment*/immunology , Neovascularization, Pathologic*/genetics , Mitochondria*/genetics , Mitochondria*/metabolism , Gene Expression Regulation, Neoplastic*, Humans ; Prognosis ; Male ; Female ; Angiogenesis

The role of CD70 expression in lymphoma pathogenesis, progression, and treatment.

Authors: Zheng X Liu T

Source: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2025 Dec; Vol. 216, pp. 104944. Date of Electronic Publication: 2025 Sep 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE

MeSH Terms: CD27 Ligand*/genetics , CD27 Ligand*/metabolism , Lymphoma*/therapy , Lymphoma*/pathology , Lymphoma*/metabolism , Lymphoma*/etiology , Lymphoma*/genetics , Gene Expression Regulation, Neoplastic*, Humans ; Disease Progression ; Animals

Experimental and in silico analysis of LINC01279 expression in tumor of patients with breast cancer.

Authors: Mokhtari N Ahmadi N Moradi S et al.

Source: Journal of applied genetics [J Appl Genet] 2025 Dec; Vol. 66 (4), pp. 933-945. Date of Electronic Publication: 2024 Oct 28.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: England NLM ID: 9514582 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3883 (Electronic) Linking ISSN: 12341983 NLM ISO Abbreviation: J Appl Genet Subsets: MEDLINE

MeSH Terms: RNA, Long Noncoding*/genetics , Breast Neoplasms*/genetics , Breast Neoplasms*/pathology , Gene Expression Regulation, Neoplastic* , Biomarkers, Tumor*/genetics, Humans ; Female ; Gene Regulatory Networks ; Computer Simulation ; Computational Biology ; Gene Expression Profiling ; Middle Aged ; Gene Ontology

PET/CT imaging of esophageal cancer targeting tumor cell specific αvβ6-integrin expression.

Authors: Bendová KD Groll T Neužilová B et al.

Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2025 Dec; Vol. 53 (1), pp. 607-618. Date of Electronic Publication: 2025 Jun 20.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE

MeSH Terms: Esophageal Neoplasms*/diagnostic imaging , Esophageal Neoplasms*/metabolism , Esophageal Neoplasms*/pathology , Positron Emission Tomography Computed Tomography* , Integrins*/metabolism , Antigens, Neoplasm*/metabolism , Gene Expression Regulation, Neoplastic*, Animals ; Humans ; Mice ; Cell Line, Tumor ; Female ; Male ; Tissue Distribution ; Gallium Radioisotopes ; Middle Aged ; Aged

FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression.

Authors: Wang J Zhang C Wang L et al.

Source: Cell biochemistry and biophysics [Cell Biochem Biophys] 2025 Dec; Vol. 83 (4), pp. 4551-4566. Date of Electronic Publication: 2025 May 30.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9701934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0283 (Electronic) Linking ISSN: 10859195 NLM ISO Abbreviation: Cell Biochem Biophys Subsets: MEDLINE

MeSH Terms: Hepatocyte Nuclear Factor 3-alpha*/metabolism , Hepatocyte Nuclear Factor 3-alpha*/genetics , Tongue Neoplasms*/pathology , Tongue Neoplasms*/metabolism , Tongue Neoplasms*/genetics , Disease Progression* , Gene Expression Regulation, Neoplastic* , Phospholipid Transfer Proteins*/genetics , Phospholipid Transfer Proteins*/metabolism , Phospholipid Transfer Proteins*/antagonists & inhibitors , Carcinoma, Squamous Cell*/pathology , Carcinoma, Squamous Cell*/metabolism , Carcinoma, Squamous Cell*/genetics, Humans ; Animals ; Cell Line, Tumor ; Mice ; Cell Proliferation ; Promoter Regions, Genetic ; Cell Movement ; Apoptosis ; Mice, Nude ; Down-Regulation

Identification of ALDH7A1 as a DNA-methylation-driven gene in lung squamous cell carcinoma.

Authors: Liang G He J Chen T et al.

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2442529. Date of Electronic Publication: 2024 Dec 23.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH Terms: Lung Neoplasms*/genetics , Lung Neoplasms*/mortality , Lung Neoplasms*/metabolism , DNA Methylation* , Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/metabolism , Gene Expression Regulation, Neoplastic*, Humans ; Prognosis ; Male ; Female ; Aldehyde Dehydrogenase/genetics ; Aldehyde Dehydrogenase/metabolism ; Middle Aged ; Cell Line, Tumor ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Signal Transduction/genetics

Age-diet interactions significantly influence intratumoral gene expression, gut microbiome signature and tumor microenvironment in colorectal cancer.

Authors: Soni S Mittal P Lo JH et al.

Source: Neoplasia (New York, N.Y.) [Neoplasia] 2025 Dec; Vol. 70, pp. 101245. Date of Electronic Publication: 2025 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5586 (Electronic) Linking ISSN: 14765586 NLM ISO Abbreviation: Neoplasia Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/etiology , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/microbiology , Gastrointestinal Microbiome* , Tumor Microenvironment*/genetics , Diet* , Gene Expression Regulation, Neoplastic* , Aging*, Animals ; Mice ; Humans ; Disease Models, Animal ; Age Factors ; Male

Identification of a novel p65-p68 loop: A crucial determinant for p68 gene regulation in oncogenesis.

Authors: Ghosh MK Kumar S Khare V et al.

Source: Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2025 Dec; Vol. 1868 (4), pp. 195120. Date of Electronic Publication: 2025 Nov 06.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-4320 (Electronic) Linking ISSN: 18749399 NLM ISO Abbreviation: Biochim Biophys Acta Gene Regul Mech Subsets: MEDLINE

MeSH Terms: Transcription Factor RelA*/genetics , Transcription Factor RelA*/metabolism , Gene Expression Regulation, Neoplastic* , Carcinogenesis*/genetics , DEAD-box RNA Helicases*/genetics , DEAD-box RNA Helicases*/metabolism , Glioma*/genetics , Glioma*/pathology , Glioma*/metabolism , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism, Humans ; Animals ; Cell Line, Tumor ; Mice ; Cell Proliferation/genetics ; Cell Movement/genetics ; Promoter Regions, Genetic ; Signal Transduction ; Mice, Nude

Identification and validation of the m6A-binding protein LRPPRC to promote tumorigenesis in multiple myeloma.

Authors: Tang J Li J Qin S et al.

Source: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2523082. Date of Electronic Publication: 2025 Jul 03.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH Terms: Multiple Myeloma*/metabolism , Multiple Myeloma*/pathology , Multiple Myeloma*/genetics , Neoplasm Proteins*/genetics , Neoplasm Proteins*/metabolism , Neoplasm Proteins*/biosynthesis , Gene Expression Regulation, Neoplastic* , Carcinogenesis*/genetics , Carcinogenesis*/metabolism, Humans ; Cell Line, Tumor ; Apoptosis ; Male ; Female ; Prognosis ; Cell Proliferation ; Adenosine/analogs & derivatives ; Adenosine/metabolism

The Expression of SIRT3 in Endometrial Carcinoma and Its Effect on Promoting Apoptosis of Ishikawa Cells.

Authors: Zhao X Yin X

Source: Biochemical genetics [Biochem Genet] 2025 Dec; Vol. 63 (6), pp. 5432-5446. Date of Electronic Publication: 2024 Dec 13.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0126611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4927 (Electronic) Linking ISSN: 00062928 NLM ISO Abbreviation: Biochem Genet Subsets: MEDLINE

MeSH Terms: Sirtuin 3*/genetics , Sirtuin 3*/metabolism , Apoptosis* , Endometrial Neoplasms*/genetics , Endometrial Neoplasms*/metabolism , Endometrial Neoplasms*/pathology , Gene Expression Regulation, Neoplastic*, Humans ; Female ; Cell Line, Tumor ; Reactive Oxygen Species/metabolism ; Autophagy

miR-4484 suppresses hepatocellular carcinoma progression via targeting KIF2C .

Authors: Lin J Cai Y Chen Z et al.

Source: RNA biology [RNA Biol] 2025 Dec; Vol. 22 (1), pp. 1-20. Date of Electronic Publication: 2025 Oct 04.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101235328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8584 (Electronic) Linking ISSN: 15476286 NLM ISO Abbreviation: RNA Biol Subsets: MEDLINE

MeSH Terms: Carcinoma, Hepatocellular*/genetics , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/mortality , Liver Neoplasms*/genetics , Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Liver Neoplasms*/mortality , Kinesins*/genetics , Kinesins*/metabolism , MicroRNAs*/genetics , Gene Expression Regulation, Neoplastic*, Humans ; Animals ; Cell Proliferation/genetics ; Mice ; Cell Line, Tumor ; Disease Progression ; Mice, Nude ; Prognosis ; Cell Cycle ; Male

Early-stage lung adenocarcinoma affects DNA methylation and gene expression in adjacent tissues.

Authors: Wu Y Wang Y Tang Y et al.

Source: EMBO reports [EMBO Rep] 2025 Dec; Vol. 26 (23), pp. 5931-5958. Date of Electronic Publication: 2025 Nov 03.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH Terms: DNA Methylation* , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/metabolism , Gene Expression Regulation, Neoplastic* , Adenocarcinoma*/genetics , Adenocarcinoma*/pathology, Humans ; Adenocarcinoma of Lung ; CpG Islands ; Prognosis ; Female ; Male ; Neoplasm Staging ; Middle Aged ; Gene Expression Profiling ; Aged ; Wnt Proteins/genetics ; Wnt Proteins/metabolism ; Cohort Studies

RNA-binding protein quaking: a multifunctional regulator in tumour progression.

Authors: Zhu W Yang W Sun G et al.

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2443046. Date of Electronic Publication: 2024 Dec 23.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH Terms: Disease Progression* , Gene Expression Regulation, Neoplastic* , Neoplasms*/metabolism , Neoplasms*/genetics , Neoplasms*/pathology , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics, Humans ; Alternative Splicing ; RNA, Messenger/metabolism ; Signal Transduction/genetics ; Tumor Microenvironment/genetics

Integrative analysis of RiboSis-related gene expression in colorectal cancer: implications for prognosis and immunotherapy.

Authors: Song W Zhou M Wang Y et al.

Source: Apoptosis : an international journal on programmed cell death [Apoptosis] 2025 Dec; Vol. 30 (11-12), pp. 2810-2829. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-675X (Electronic) Linking ISSN: 13608185 NLM ISO Abbreviation: Apoptosis Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/immunology , Gene Expression Regulation, Neoplastic* , Immunotherapy* , Ribosomes*/genetics , Ribosomes*/metabolism, Humans ; Prognosis ; Biomarkers, Tumor/genetics ; Female ; Male ; Gene Regulatory Networks

Downregulated expression of dual-specificity phosphatase-1 in multiple myeloma as a predictor of poor survival outcomes.

Authors: Guo D Lu J Hong L et al.

Source: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2474271. Date of Electronic Publication: 2025 Mar 12.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH Terms: Multiple Myeloma*/mortality , Multiple Myeloma*/genetics , Multiple Myeloma*/enzymology , Multiple Myeloma*/pathology , Dual Specificity Phosphatase 1*/genetics , Dual Specificity Phosphatase 1*/biosynthesis , Gene Expression Regulation, Neoplastic* , Down-Regulation*, Humans ; Female ; Male ; Prognosis ; Middle Aged ; Proto-Oncogene Mas ; Aged ; Biomarkers, Tumor