Výsledky vyhľadávania - "Gene Expression/drug effects"

Limited Impact of 6-Mercaptopurine on Inflammation-Induced Chemokines Expression Profile in Primary Cultures of Enteric Nervous System

Autori: Kneusels, Jan Kaehler, Meike Cascorbi, Ingolf a ďalší

Prispievatelia: Kneusels, Jan Kaehler, Meike Cascorbi, Ingolf a ďalší

Zdroj: Neurochem Res

Predmety: MESH: Inflammation, 6-Mercaptopurine, Lipopolysaccharides, 0301 basic medicine, MESH: Gene Expression, MESH: Rats, Interleukin-1beta/genetics [MeSH], Tumor Necrosis Factor-alpha/genetics [MeSH], Enteric Nervous System/cytology [MeSH], Inflammation/chemically induced [MeSH], Rats [MeSH], Lipopolysaccharides [MeSH], Animals [MeSH], Gene Expression/drug effects [MeSH], Inflammatory bowel diseases, Neurons/drug effects [MeSH], CXC motif ligand chemokines, Interleukin-1beta/pharmacology [MeSH], Mercaptopurine/pharmacology [MeSH], Mice [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Original Paper, Cells, Cultured [MeSH], Tumor Necrosis Factor-alpha/metabolism [MeSH], Enteric glial cells, Interleukin-1beta/metabolism [MeSH], Enteric nervous system, Tumor Necrosis Factor-alpha/pharmacology [MeSH], [SDV]Life Sciences [q-bio], Interleukin-1beta, MESH: Neurons, Anti-Inflammatory Agents, Gene Expression, Enteric Nervous System, Mice, 03 medical and health sciences, MESH: Interleukin-1beta, Animals, MESH: Animals, MESH: Mice, Cells, Cultured, Inflammation, Neurons, MESH: Cells, 0303 health sciences, Cultured, MESH: Enteric Nervous System, Mercaptopurine, Tumor Necrosis Factor-alpha, Rats, 3. Good health, [SDV] Life Sciences [q-bio], MESH: Anti-Inflammatory Agents, MESH: Tumor Necrosis Factor-alpha, MESH: Mercaptopurine, MESH: Lipopolysaccharides

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s11064-021-03324-y.pdf
https://pubmed.ncbi.nlm.nih.gov/33864170
https://www.ncbi.nlm.nih.gov/pubmed/33864170
https://link.springer.com/article/10.1007/s11064-021-03324-y
https://europepmc.org/article/PMC/PMC8187225
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187225
https://link.springer.com/content/pdf/10.1007/s11064-021-03324-y.pdf
https://hal.science/hal-04178448v1
https://hal.science/hal-04178448v1/document
https://doi.org/10.1007/s11064-021-03324-y
https://repository.publisso.de/resource/frl:6445958

Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis

Autori: Pujo, Julien Petitfils, Camille Le Faouder, Pauline a ďalší

Prispievatelia: Pujo, Julien Petitfils, Camille Le Faouder, Pauline a ďalší

Zdroj: Gut, Vol. 70, p. 1088-1097 (2021)

Predmety: MESH: Colitis / chemically induced, 0301 basic medicine, Cell Membrane Permeability, [SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], [SDV]Life Sciences [q-bio], Chemokine CXCL1, MESH: Firmicutes / metabolism, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Interleukin-1beta, Gene Expression, Oligosaccharides, Pancreatitis-Associated Proteins, Mass Spectrometry, Mice, MESH: Gastrointestinal Microbiome / physiology, MESH: Animals, MESH: Cell Membrane Permeability, Intestinal Mucosa, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Dextran Sulfate, MESH: Oligosaccharides / pharmacology, Colitis, Lipids, Enteric bacterial microflora, Experimental colitis, MESH: Pancreatitis-Associated Proteins / genetics, enteric bacterial microflora, 3. Good health, [SDV] Life Sciences [q-bio], MESH: Interleukin-1beta / genetics, MESH: PPAR gamma / genetics, MESH: Escherichia coli / metabolism, MESH: Intestinal Mucosa / metabolism, MESH: Caco-2 Cells, experimental colitis, Firmicutes, MESH: Epithelial Cells / physiology, lipids, 03 medical and health sciences, MESH: Chemokine CXCL1 / genetics, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Escherichia coli, Animals, Humans, MESH: Mice, Molecular Biology, MESH: PPAR gamma / metabolism, MESH: Gene Expression / drug effects, MESH: Mass Spectrometry, MESH: Dextran Sulfate, MESH: Humans, Bacteroidetes, Probiotics, Epithelial Cells, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Bacteroidetes, Gastrointestinal Microbiome, PPAR gamma, probiotics, MESH: Colitis / drug therapy, MESH: Colitis / metabolism, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Caco-2 Cells, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/32978245
https://gut.bmj.com/content/70/6/1088
http://www.ncbi.nlm.nih.gov/pubmed/32978245
https://gut.bmj.com/content/gutjnl/70/6/1088.full.pdf
https://gut.bmj.com/content/early/2020/09/25/gutjnl-2020-321173
https://pubmed.ncbi.nlm.nih.gov/32978245/
https://www.ncbi.nlm.nih.gov/pubmed/32978245
https://hdl.handle.net/2078.1/238801
https://hal.science/hal-04703019v1
https://doi.org/10.1136/gutjnl-2020-321173
https://hal.inrae.fr/hal-03036283v1
https://doi.org/10.1136/gutjnl-2020-321173

Effect of intravenous IgG therapy on natural killer cell function related to Fc gamma receptor gene expression

Autori: Papaserafeim, Maria Jandus, Peter Iancu Ferfoglia, Ruxandra a ďalší

Zdroj: The journal of allergy and clinical immunology, Vol. 146, No 3 (2020) pp. 667-670

Predmety: ddc:616, Adult, Male, 0301 basic medicine, 0303 health sciences, Immunoglobulins, Intravenous / pharmacology, Gene Expression, Immunoglobulins, Intravenous, Receptors, Fc, Middle Aged, Gene Expression / drug effects, Polymorphism, Single Nucleotide, ddc:616.8, Killer Cells, Natural / drug effects, Killer Cells, Natural, Receptors, Fc / immunology, 03 medical and health sciences, Immunoglobulins, Intravenous / therapeutic use, Humans, Female, Killer Cells, Natural / immunology, Receptors, Fc / genetics, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/32311389
https://www.ncbi.nlm.nih.gov/pubmed/32311389
https://www.jacionline.org/article/S0091674920304851/pdf
https://www.jacionline.org/article/S0091-6749(20)30485-1/fulltext
https://pubmed.ncbi.nlm.nih.gov/32311389/
https://www.sciencedirect.com/science/article/pii/S0091674920304851
https://archive-ouverte.unige.ch/unige:159740

Attenuation of the pro-inflammatory signature of lung cancer-derived mesenchymal stromal cells by statins

Autori: Sabine Galland Patricia Martin Giulia Fregni a ďalší

Zdroj: Cancer letters, vol. 484, pp. 50-64

Predmety: Aged, 80 and over, Male, 0301 basic medicine, Simvastatin, 0303 health sciences, Lung Neoplasms, Interleukin-6, Gene Expression, Mesenchymal Stem Cells, Middle Aged, Aged, Carcinoma, Squamous Cell/genetics, Carcinoma, Squamous Cell/metabolism, Carcinoma, Squamous Cell/pathology, Cells, Cultured, Chemokine CCL2/genetics, Chemokine CCL2/metabolism, Chemokine CCL3/genetics, Chemokine CCL3/metabolism, Cytokines/genetics, Cytokines/metabolism, Female, Gene Expression/drug effects, Humans, Inflammation Mediators/metabolism, Interleukin-6/genetics, Interleukin-6/metabolism, Lung Neoplasms/genetics, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Mesenchymal Stem Cells/cytology, Mesenchymal Stem Cells/drug effects, Mesenchymal Stem Cells/metabolism, Simvastatin/pharmacology, Tumor Cells, Cultured, Tumor Microenvironment/drug effects, Tumor Microenvironment/genetics, CCL2, CCL3, Lung cancer, Mesenchymal stromal cells, 3. Good health, 03 medical and health sciences, Carcinoma, Squamous Cell, Tumor Microenvironment, Cytokines, Inflammation Mediators, Chemokine CCL2, Chemokine CCL3

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/32418888
https://www.sciencedirect.com/science/article/pii/S0304383520302330
https://www.sciencedirect.com/science/article/abs/pii/S0304383520302330
https://pubmed.ncbi.nlm.nih.gov/32418888/
https://www.ncbi.nlm.nih.gov/pubmed/32418888
https://serval.unil.ch/notice/serval:BIB_2044EA0B5E7B
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_2044EA0B5E7B5
https://serval.unil.ch/resource/serval:BIB_2044EA0B5E7B.P001/REF.pdf

Suppressive activity of Vδ2+ γδ T cells on αβ T cells is licensed by TCR signaling and correlates with signal strength

Autori: Karin Schilbach Naomi Krickeberg Carlotta Kaißer a ďalší

Zdroj: Cancer Immunol Immunother

Predmety: Interleukin-15, Receptors, Antigen, T-Cell, Gene Expression, Apoptosis, Receptors, Antigen, T-Cell, gamma-delta, Lymphocyte Activation, B7-H1 Antigen, 03 medical and health sciences, Hemiterpenes, Organophosphorus Compounds, 0302 clinical medicine, T-Lymphocyte Subsets, Cell Line, Tumor, Apoptosis/immunology [MeSH], Cell Line, Tumor [MeSH], TCR signal strength, T-Lymphocyte Subsets/immunology [MeSH], Gene Expression/drug effects [MeSH], B7-H1 Antigen/metabolism [MeSH], γδ T cells, Lymphocyte Activation/drug effects [MeSH], Original Article, T-Lymphocyte Subsets/metabolism [MeSH], Gene Expression/immunology [MeSH], Signal Transduction/drug effects [MeSH], Immune Tolerance/immunology [MeSH], B7-H1 Antigen/genetics [MeSH], Immune Tolerance/drug effects [MeSH], T-Lymphocyte Subsets/drug effects [MeSH], Interleukin-15/pharmacology [MeSH], IPP, Receptors, Antigen, T-Cell, gamma-delta/immunology [MeSH], B7-H1 Antigen/immunology [MeSH], Receptors, Antigen, T-Cell/metabolism [MeSH], Lymphocyte Activation/immunology [MeSH], Humans [MeSH], Apoptosis/drug effects [MeSH], Immune Tolerance/genetics [MeSH], Immunosuppression, Receptors, Antigen, T-Cell/immunology [MeSH], Signal Transduction/immunology [MeSH], Organophosphorus Compounds/pharmacology [MeSH], TCR-induced immune suppression, Receptors, Antigen, T-Cell, gamma-delta/metabolism [MeSH], Cells, Cultured [MeSH], Hemiterpenes/pharmacology [MeSH], Cell Proliferation/drug effects [MeSH], Immune Tolerance, Humans, Cells, Cultured, Cell Proliferation, Signal Transduction

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00262-019-02469-8.pdf
https://pubmed.ncbi.nlm.nih.gov/31982940
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113223
https://pubmed.ncbi.nlm.nih.gov/31982940/
https://www.ncbi.nlm.nih.gov/pubmed/31982940
https://link.springer.com/article/10.1007/s00262-019-02469-8
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202002230448839558
https://paperity.org/p/231177119/suppressive-activity-of-vd2-gd-t-cells-on-ab-t-cells-is-licensed-by-tcr-signaling-and
https://repository.publisso.de/resource/frl:6470318

The faroes statement: human health effects of developmental exposure to chemicals in our environment.

Autori: Grandjean, Philippe Bellinger, David Bergman, Åke a ďalší

Zdroj: Basic & Clinical Pharmacology & Toxicology. 102(2):73-5

Predmety: Animals, Child Development/drug effects, Embryonic Development/drug effects, Environmental Exposure/*adverse effects, Environmental Pollutants/*toxicity, Female, Fetal Development/drug effects, Gene Expression/drug effects, Humans, Infant, Newborn, Maternal-Fetal Exchange, Pregnancy, Prenatal Exposure Delayed Effects

Popis súboru: electronic

Prístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-13274

Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter

Autori: Egner, R. Rosenthal, F. E. Kralli, A. a ďalší

Predmety: ATP-Binding Cassette Transporters/antagonists & inhibitors/chemistry/*genetics Amino Acid Sequence Amino Acid Substitution Antibiotics, Antifungal/pharmacology Biological Transport Carrier Proteins/genetics/physiology Cell Membrane/chemistry Cloning, Molecular Cycloheximide/pharmacology DNA-Binding Proteins/genetics/physiology Dexamethasone/metabolism/pharmacology Drug Resistance, Microbial/*genetics Drug Resistance, Multiple/*genetics Estradiol/metabolism Gene Expression/drug effects Heat-Shock Proteins/genetics/physiology Membrane Proteins/antagonists & inhibitors/chemistry/*genetics Molecular Sequence Data Mutagenesis Rhodamine 123 Rhodamines/metabolism/pharmacology Saccharomyces cerevisiae/*drug effects/genetics *Saccharomyces cerevisiae Proteins Sequence Alignment Substrate Specificity Tacrolimus/*pharmacology Tacrolimus Binding Proteins

Relation: Molecular Biology of the Cell; https://iris.unil.ch/handle/iris/92913; serval:BIB_040973231336; 000072135200022; 9450972

Dostupnosť: https://iris.unil.ch/handle/iris/92913

Hypothalamic ghrelin treatment modulates NPY-but not CRH-ergic activity in adrenalectomized rats subjected to food restriction: Evidence of a novel hypothalamic ghrelin effect

Autori: Spinedi, E. Voirol, M. J. Verdumo, C. a ďalší

Predmety: Adrenalectomy Adrenocorticotropic Hormone/blood Animals Body Weight Corticotropin-Releasing Hormone/*metabolism Drug Administration Routes Eating/drug effects Food Deprivation/*physiology Gene Expression/drug effects Glucocorticoids/physiology Hypothalamus/*drug effects/metabolism Injections/methods Leptin/blood Male Neuropeptide Y/*metabolism Peptide Hormones/administration & dosage/blood/*pharmacology RNA, Messenger/metabolism Rats Rats, Wistar

Popis súboru: application/pdf

Relation: Endocrine journal; https://iris.unil.ch/handle/iris/86286; serval:BIB_4F35381F77E9; 000240215000014

Dostupnosť: https://iris.unil.ch/handle/iris/86286
https://doi.org/10.1385/ENDO:29:3:477

Metformin inhibits adenosine 5'-monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons

Autori: Chau-Van, C. Gamba, M. Salvi, R. a ďalší

Predmety: Animals Cells, Cultured Dose-Response Relationship, Drug Enzyme Activation/drug effects Gene Expression/drug effects Glucose/administration & dosage/pharmacology Hypoglycemic Agents/*pharmacology Hypothalamus/cytology/drug effects/*metabolism Metformin/*pharmacology Multienzyme Complexes/*antagonists & inhibitors/metabolism Neurons/drug effects/*metabolism Neuropeptide Y/*antagonists & inhibitors/genetics/metabolism Osmolar Concentration Phosphorylation/drug effects Pro-Opiomelanocortin/antagonists & inhibitors/genetics/metabolism Protein-Serine-Threonine Kinases/*antagonists & inhibitors/metabolism Rats

Relation: Endocrinology; https://iris.unil.ch/handle/iris/83524; serval:BIB_2249C6A6C51C; 000243520500006

Dostupnosť: https://iris.unil.ch/handle/iris/83524
https://doi.org/10.1210/en.2006-1237

Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

Autori: Larsen, L. Storling, J. Darville, M. a ďalší

Predmety: Animals Apoptosis/genetics Blotting, Western Cell Line, Tumor Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors/*physiology Flavonoids/pharmacology *Gene Expression/drug effects/physiology Humans Imidazoles/pharmacology Insulin/*secretion Insulin-Secreting Cells/drug effects/*physiology/secretion Interleukin-1/pharmacology/*physiology MAP Kinase Kinase 4/antagonists & inhibitors/physiology Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors/physiology NF-kappa B/*physiology Nitric Oxide Synthase Type II/biosynthesis/*genetics Phosphorylation Pyridines/pharmacology Rats Serine/analysis Synaptotagmin I/chemistry/physiology p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors/physiology

Relation: Diabetologia; https://iris.unil.ch/handle/iris/63519; serval:BIB_1DE751435368; 000233721600022

Dostupnosť: https://iris.unil.ch/handle/iris/63519
https://doi.org/10.1007/s00125-005-0039-9

Food intake-induced leptin secretion modulates hypothalamo-pituitary-adrenal axis response and hypothalamic Ob-Rb expression to insulin administration

Autori: Giovambattista, A. Chisari, A. N. Gaillard, R. C. a ďalší

Predmety: Adrenocorticotropic Hormone/blood Animals Blood Glucose Carrier Proteins/*genetics Eating/*physiology Energy Metabolism/physiology Fasting/physiology Female Gene Expression/drug effects/physiology Homeostasis/drug effects/physiology Hypoglycemic Agents/*pharmacology Hypothalamo-Hypophyseal System/drug effects/*metabolism/secretion Insulin/*pharmacology Leptin/blood/*secretion Mice Mice, Inbred BALB C Pituitary-Adrenal System/drug effects/*metabolism/secretion RNA, Messenger/analysis *Receptors, Cell Surface Stress/metabolism

Relation: Neuroendocrinology; https://iris.unil.ch/handle/iris/54401; serval:BIB_2E71BFD26672; 000166275400003

Dostupnosť: https://iris.unil.ch/handle/iris/54401
https://doi.org/10.1159/000054603

ERK signaling pathway regulates sleep duration through activity-induced gene expression during wakefulness.

Autori: Mikhail, C. Vaucher, A. Jimenez, S. a ďalší

Predmety: Animals, Blotting, Western, Cells, Cultured, Cytoskeletal Proteins/genetics, Cytoskeletal Proteins/metabolism, DNA-Binding Proteins/genetics, DNA-Binding Proteins/metabolism, Gene Expression/drug effects, Gene Expression/genetics, Homer Scaffolding Proteins/genetics, Homer Scaffolding Proteins/metabolism, MAP Kinase Signaling System/drug effects, MAP Kinase Signaling System/genetics, Mice, Inbred C57BL, Knockout, Transgenic, Mitogen-Activated Protein Kinase 1/genetics, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/genetics, Mitogen-Activated Protein Kinase 3/metabolism, Nerve Tissue Proteins/genetics, Nerve Tissue Proteins/metabolism, Neurotransmitter Agents/pharmacology, Phosphorylation, Reverse Transcriptase Polymerase Chain Reaction, Sleep/genetics, Sleep Deprivation

Popis súboru: application/pdf

Relation: Science Signaling; https://iris.unil.ch/handle/iris/53392; serval:BIB_3F8B9D2AAC2B; 000393784700001

Dostupnosť: https://iris.unil.ch/handle/iris/53392
https://doi.org/10.1126/scisignal.aai9219

Cytokine regulation of TNF-alpha mRNA and protein production by unprimed macrophages from C57Bl/6 and NZW mice

Autori: Schook, L. B. Albrecht, H. Gallay, P. a ďalší

Predmety: Animals Cytokines/*pharmacology Gene Expression/drug effects Interleukin-10/pharmacology Interleukin-2/pharmacology Interleukin-6/metabolism Lipopolysaccharides/pharmacology Macrophage Colony-Stimulating Factor/pharmacology Macrophages/*metabolism Mice Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred NOD RNA, Messenger/genetics Tumor Necrosis Factor-alpha/*metabolism

Relation: Journal of Leukocyte Biology; https://iris.unil.ch/handle/iris/51627; serval:BIB_1B4FC08FD88B; A1994PK36000014; 7930949

Dostupnosť: https://iris.unil.ch/handle/iris/51627

Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment.

Autori: Guzman-Ayala, M. Ben-Haim, N. Beck, S. a ďalší

Predmety: Animals, Cell Differentiation, Female, Fibroblast Growth Factor 4, Fibroblast Growth Factors/genetics, Furin/deficiency, Furin/genetics, Gene Expression/drug effects, Mice, Inbred C57BL, Knockout, Models, Biological, Nodal Protein, Pregnancy, Proprotein Convertases, Protein Processing, Post-Translational, Proto-Oncogene Proteins/genetics, Recombinant Proteins/pharmacology, Serine Endopeptidases/deficiency, Serine Endopeptidases/genetics, Stem Cells/cytology, Stem Cells/metabolism, Tissue Culture Techniques, Transforming Growth Factor beta/genetics, Transforming Growth Factor beta/metabolism, Trophoblasts/cytology, Trophoblasts/metabolism

Relation: Proceedings of the National Academy of Sciences; https://iris.unil.ch/handle/iris/33160; serval:BIB_31437; 000224922300021

Dostupnosť: https://iris.unil.ch/handle/iris/33160
https://doi.org/10.1073/pnas.0405429101

Pro-inflammatory cytokines induce the transcription factors C/EBPbeta and C/EBPdelta in astrocytes.

Autori: Cardinaux, J.R. Allaman, I. Magistretti, P.J.

Predmety: Animals, Astrocytes/cytology, Astrocytes/drug effects, Blotting, Northern, CCAAT-Enhancer-Binding Proteins, Cells, Cultured, Cerebral Cortex/cytology, Complement C3/biosynthesis, Complement C3/genetics, Cycloheximide/pharmacology, Cytokines/metabolism, Cytokines/pharmacology, DNA-Binding Proteins/biosynthesis, DNA-Binding Proteins/genetics, Gene Expression/drug effects, Interferon-gamma/pharmacology, Interleukin-1/pharmacology, Interleukin-6/pharmacology, Lipopolysaccharides/pharmacology, Mice, Nuclear Proteins/biosynthesis, Nuclear Proteins/genetics, Protein Isoforms/biosynthesis, Protein Isoforms/genetics, Protein Synthesis Inhibitors/pharmacology, RNA, Messenger/biosynthesis, Serpins

Relation: Glia; https://iris.unil.ch/handle/iris/258477; serval:BIB_F0133DCB1181; 000084388600009

Dostupnosť: https://iris.unil.ch/handle/iris/258477

Interleukin 1 beta suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes

Autori: Lotz, M. Rosen, F. McCabe, G. a ďalší

Predmety: Adult Aged Alkaline Phosphatase/metabolism Blotting, Western Cartilage, Articular/drug effects/*metabolism Cells, Cultured Culture Media, Conditioned DNA/metabolism Diphosphates/*metabolism Gene Expression/drug effects Homeostasis Humans Interleukin-1/*pharmacology Kinetics Membrane Glycoproteins/*biosynthesis Middle Aged *Phosphoric Diester Hydrolases Pyrophosphatases/*metabolism RNA, Messenger/analysis/biosynthesis Transforming Growth Factor beta/antagonists & inhibitors/*pharmacology

Relation: Proceedings of the National Academy of Sciences; https://iris.unil.ch/handle/iris/256756; serval:BIB_DF1E41A390B8; A1995TB46700088; 7479785

Dostupnosť: https://iris.unil.ch/handle/iris/256756
https://doi.org/10.1073/pnas.92.22.10364

Increased male offspring's risk of metabolic-neuroendocrine dysfunction and overweight after fructose-rich diet intake by the lactating mother.

Autori: Alzamendi, A. Castrogiovanni, D. Gaillard, R.C. a ďalší

Predmety: Adipokines/blood, Animals, Newborn, Blotting, Western, Body Weight/drug effects, Body Weight/physiology, Dietary Carbohydrates/administration & dosage, Eating/drug effects, Eating/physiology, Female, Fructose/administration & dosage, Gene Expression/drug effects, Hypothalamus/drug effects, Hypothalamus/metabolism, Lactation/physiology, Leptin/blood, Leptin/pharmacology, Male, Metabolic Diseases/blood, Metabolic Diseases/physiopathology, Neurosecretory Systems/drug effects, Neurosecretory Systems/physiopathology, Overweight/physiopathology, Pregnancy, Rats, Sprague-Dawley, Reverse Transcriptase Polymerase Chain Reaction, Risk Factors, STAT3 Transcription Factor/genetics

Relation: Endocrinology; https://iris.unil.ch/handle/iris/251923; serval:BIB_E79A9F919EE8; 000281252000018

Dostupnosť: https://iris.unil.ch/handle/iris/251923
https://doi.org/10.1210/en.2009-1353

Fusaric acid-producing strains of Fusarium oxysporum alter 2,4-diacetylphloroglucinol biosynthetic gene expression in Pseudomonas fluorescens CHA0 in vitro and in the rhizosphere of wheat.

Autori: Notz, R. Maurhofer, M. Dubach, H. a ďalší

Predmety: Fusaric Acid/metabolism, Fusaric Acid/pharmacology, Fusarium/classification, Fusarium/metabolism, Gene Expression/drug effects, Phloroglucinol/analogs & derivatives, Phloroglucinol/metabolism, Pseudomonas fluorescens/drug effects, Pseudomonas fluorescens/genetics, Recombinant Fusion Proteins/genetics, Rhizobiaceae/drug effects, Rhizobiaceae/physiology, Triticum/microbiology

Relation: Applied and Environmental Microbiology; https://iris.unil.ch/handle/iris/235638; serval:BIB_E6ED12A83FC9; 000175407300017

Dostupnosť: https://iris.unil.ch/handle/iris/235638
https://doi.org/10.1128/AEM.68.5.2229-2235.2002

Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK

Autori: Loffing, J. Zecevic, M. Feraille, E. a ďalší

Predmety: Aldosterone/*pharmacology Animals Biological Transport/drug effects/physiology Cell Membrane/metabolism Cell Polarity/physiology Epithelial Sodium Channel Gene Expression/drug effects/physiology Immediate-Early Proteins Kidney Tubules, Collecting/drug effects/*enzymology Male *Nuclear Proteins Oocytes/physiology Patch-Clamp Techniques Protein-Serine-Threonine Kinases/genetics/*metabolism RNA, Messenger/analysis Rats Rats, Wistar Sodium/metabolism Sodium Channels/genetics/*metabolism Xenopus laevis

Relation: American journal of physiology. Renal, fluid and electrolyte physiology; https://iris.unil.ch/handle/iris/219678; serval:BIB_7F99A1948989; 000167461600014

Dostupnosť: https://iris.unil.ch/handle/iris/219678

Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model.

Autori: Yang, X. Mertens, B. Lehtonen, E. a ďalší

Predmety: Adrenergic Agents/administration & dosage, Adrenergic Agents/adverse effects, Animals, Dependovirus/genetics, Dopamine/analysis, Dopamine/biosynthesis, Doxycycline/administration & dosage, Female, Gene Expression/drug effects, Gene Transfer Techniques, Genetic Vectors/administration & dosage, Genetic Vectors/genetics, Glial Cell Line-Derived Neurotrophic Factor/administration & dosage, Glial Cell Line-Derived Neurotrophic Factor/biosynthesis, Humans, Motor Activity/drug effects, Oxidopamine/administration & dosage, Oxidopamine/adverse effects, Parkinson Disease, Secondary/chemically induced, Secondary/metabolism, Rats, Time Factors, Tyrosine 3-Monooxygenase/analysis, Tyrosine 3-Monooxygenase/biosynthesis

Relation: Journal of Gene Medicine; 1521-2254[electronic], 1099-498X[linking]; https://iris.unil.ch/handle/iris/219109; serval:BIB_8F63F8819274

Dostupnosť: https://iris.unil.ch/handle/iris/219109
https://doi.org/10.1002/jgm.1377