Suchergebnisse - "Galanin"

Galanin(1-15) and Naltrexone: A novel approach for alcohol use disorder in rats, involving the mesolimbic system.

Autoren: Flores-Gómez M Cantero-García N Pineda-Gómez JP et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Jul; Vol. 188, pp. 118170. Date of Electronic Publication: 2025 May 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: Naltrexone*/pharmacology , Naltrexone*/administration & dosage , Naltrexone*/therapeutic use , Galanin*/pharmacology , Galanin*/administration & dosage , Galanin*/therapeutic use , Alcoholism*/drug therapy , Alcoholism*/metabolism , Narcotic Antagonists*/pharmacology , Limbic System*/drug effects , Limbic System*/metabolism, Animals ; Male ; Self Administration ; Rats ; Alcohol Drinking/drug therapy ; Reward ; Rats, Wistar ; Receptor, Galanin, Type 2/metabolism ; Receptor, Galanin, Type 2/antagonists & inhibitors ; Ethanol/administration & dosage ; Nucleus Accumbens/drug effects ; Nucleus Accumbens/metabolism ; Drug-Seeking Behavior/drug effects ; Mesolimbic System ; Peptides

Multifaceted role of galanin in brain excitability.

Autoren: Rieser NN Ronchetti M Hotz ALL et al.

Quelle: ELife [Elife] 2025 Jul 04; Vol. 13. Date of Electronic Publication: 2025 Jul 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/metabolism , Galanin*/pharmacology , Brain*/physiology , Brain*/drug effects, Animals ; Zebrafish ; Seizures/chemically induced ; Seizures/physiopathology ; Receptor, Galanin, Type 1/metabolism ; Pentylenetetrazole ; Larva

A new pharmacological strategy against treatment-resistant depression.

Autoren: Pineda-Gómez JP Millón C Cantero-García N et al.

Quelle: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2025 Jan 10; Vol. 136, pp. 111191. Date of Electronic Publication: 2024 Nov 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 8211617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4216 (Electronic) Linking ISSN: 02785846 NLM ISO Abbreviation: Prog Neuropsychopharmacol Biol Psychiatry Subsets: MEDLINE

MeSH-Schlagworte: Depressive Disorder, Treatment-Resistant*/drug therapy , Depressive Disorder, Treatment-Resistant*/metabolism , Fluoxetine*/pharmacology , Fluoxetine*/therapeutic use , Antidepressive Agents*/therapeutic use , Antidepressive Agents*/pharmacology , Galanin*/therapeutic use , Galanin*/pharmacology, Animals ; Rats, Inbred WKY ; Male ; Receptor, Serotonin, 5-HT1A/metabolism ; Receptor, Serotonin, 5-HT1A/genetics ; Rats ; Corticosterone/blood ; Corticosterone/metabolism ; Disease Models, Animal ; Receptor, Galanin, Type 2/metabolism ; Receptor, Galanin, Type 2/antagonists & inhibitors ; Drug Therapy, Combination ; Anhedonia/drug effects

Differential activation of six galanin receptors by the spexin peptide in yellowtail kingfish (Seriola lalandi).

Autoren: Wang B Tian Z Yu Z et al.

Quelle: General and comparative endocrinology [Gen Comp Endocrinol] 2024 Dec 01; Vol. 359, pp. 114629. Date of Electronic Publication: 2024 Oct 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0370735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6840 (Electronic) Linking ISSN: 00166480 NLM ISO Abbreviation: Gen Comp Endocrinol Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Galanin*/metabolism , Perciformes*/metabolism, Animals ; Chlorocebus aethiops ; COS Cells ; Peptide Hormones/metabolism ; Peptide Hormones/pharmacology ; Receptor, Galanin, Type 2/metabolism ; Receptor, Galanin, Type 2/genetics ; Signal Transduction/drug effects ; Fish Proteins/metabolism ; Fish Proteins/genetics

Galanin-Mediated Inflammatory Responses in Zebrafish Spinal Cord Regeneration.

Autoren: Okitsu-Sakurayama S Kasica N Potoczna M et al.

Quelle: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 15859-15870. Date of Electronic Publication: 2025 Jul 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Zebrafish* , Galanin*/metabolism , Galanin*/genetics , Inflammation*/pathology , Inflammation*/metabolism , Inflammation*/genetics , Spinal Cord Regeneration*/physiology , Spinal Cord Injuries*/pathology , Spinal Cord Injuries*/physiopathology , Spinal Cord Injuries*/metabolism , Spinal Cord*/pathology , Nerve Regeneration*, Animals ; Recovery of Function ; Neutrophils/metabolism ; Zebrafish Proteins/metabolism

Galanin regulates M1/M2 polarization of microglia after spinal cord injury through TRPV1/Ca2+/CaMKII/NRF2 signaling pathway.

Autoren: Zhu Z Lu W Fang Y et al.

Quelle: International immunopharmacology [Int Immunopharmacol] 2025 Oct 30; Vol. 164, pp. 115330. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Spinal Cord Injuries*/drug therapy , Spinal Cord Injuries*/metabolism , Spinal Cord Injuries*/immunology , Microglia*/drug effects , Microglia*/metabolism , TRPV Cation Channels*/metabolism , Galanin*/pharmacology , Galanin*/therapeutic use , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/therapeutic use, Animals ; NF-E2-Related Factor 2/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Signal Transduction/drug effects ; Mice ; Mice, Inbred C57BL ; Humans ; Disease Models, Animal ; Calcium/metabolism ; Male ; Spinal Cord/drug effects ; Spinal Cord/pathology

Glyphosate-induced changes in the expression of galanin and GALR1, GALR2 and GALR3 receptors in the porcine small intestine wall.

Autoren: Palus K Chmielewska-Krzesińska M Jana B et al.

Quelle: Scientific reports [Sci Rep] 2024 Apr 17; Vol. 14 (1), pp. 8905. Date of Electronic Publication: 2024 Apr 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/metabolism , Glyphosate*/metabolism , Glyphosate*/toxicity, Animals ; Female ; Intestine, Small/drug effects ; Intestine, Small/metabolism ; Receptor, Galanin, Type 2/drug effects ; Receptor, Galanin, Type 2/genetics ; Receptor, Galanin, Type 2/metabolism ; RNA, Messenger/metabolism ; Sus scrofa/genetics ; Swine ; Receptor, Galanin, Type 1/drug effects ; Receptor, Galanin, Type 1/genetics ; Receptor, Galanin, Type 1/metabolism ; Receptor, Galanin, Type 3/drug effects ; Receptor, Galanin, Type 3/genetics ; Receptor, Galanin, Type 3/metabolism ; Herbicides/toxicity

Intracerebroventricular knockdown of NPY1R disrupts NPY1R-GALR2/TrkB heteroreceptor complexes without affecting neuroplasticity or depressive-like behaviour.

Autoren: Moreno-Madrid I Arrabal-Gómez C Romero-Imbroda J et al.

Quelle: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2025 Dec; Vol. 39 (12), pp. 1462-1475. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Neuropeptide Y*/metabolism , Receptors, Neuropeptide Y*/genetics , Neuronal Plasticity*/physiology , Receptor, trkB*/metabolism , Depression*/metabolism , Depression*/genetics , Receptor, Galanin, Type 2*/metabolism , Receptor, Galanin, Type 2*/genetics, Animals ; Rats, Sprague-Dawley ; Male ; Rats ; Hippocampus/metabolism ; Neurogenesis/physiology ; Brain-Derived Neurotrophic Factor/metabolism ; RNA, Small Interfering/administration & dosage ; Injections, Intraventricular ; Behavior, Animal ; Gene Knockdown Techniques ; Receptors, Neuropeptide ; Receptors, G-Protein-Coupled

Diagnostic role of galanin in distinguishing endometrial atypical hyperplasia and carcinoma from benign endometrial conditions.

Autoren: Ata C Bildaci TB Atlihan U et al.

Quelle: Scientific reports [Sci Rep] 2025 Oct 27; Vol. 15 (1), pp. 37438. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/blood , Endometrial Neoplasms*/diagnosis , Endometrial Neoplasms*/blood , Endometrial Neoplasms*/pathology , Endometrial Hyperplasia*/diagnosis , Endometrial Hyperplasia*/blood , Biomarkers, Tumor*/blood, Humans ; Female ; Middle Aged ; Case-Control Studies ; Adult ; Prospective Studies ; Diagnosis, Differential ; Aged ; Endometrium/pathology ; Endometrium/metabolism

Transcriptomic insights into photoperiodic regulation of goose reproduction: galanin emerges as a potential player.

Autoren: Liu J Chen X Feng Y et al.

Quelle: Poultry science [Poult Sci] 2025 Oct; Vol. 104 (10), pp. 105585. Date of Electronic Publication: 2025 Jul 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 0401150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3171 (Electronic) Linking ISSN: 00325791 NLM ISO Abbreviation: Poult Sci Subsets: MEDLINE

MeSH-Schlagworte: Photoperiod* , Reproduction*/genetics , Reproduction*/physiology , Geese*/physiology , Geese*/genetics , Transcriptome* , Galanin*/metabolism , Galanin*/genetics , Avian Proteins*/metabolism , Avian Proteins*/genetics, Animals ; Female ; Hypothalamus/metabolism ; Ovary

Impact of galanin receptors 2 and 3 double-knockout on neuroinflammation and functional recovery following traumatic brain injury.

Autoren: Brunner SM Gaisbauer S Pallier PN et al.

Quelle: Peptides [Peptides] 2025 Sep; Vol. 191, pp. 171415. Date of Electronic Publication: 2025 May 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE

MeSH-Schlagworte: Brain Injuries, Traumatic*/genetics , Brain Injuries, Traumatic*/pathology , Brain Injuries, Traumatic*/metabolism , Brain Injuries, Traumatic*/physiopathology , Receptor, Galanin, Type 2*/genetics , Receptor, Galanin, Type 2*/metabolism , Receptor, Galanin, Type 2*/deficiency , Recovery of Function* , Neuroinflammatory Diseases*/genetics , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/pathology , Receptor, Galanin, Type 3*/genetics , Receptor, Galanin, Type 3*/metabolism , Receptor, Galanin, Type 3*/deficiency, Animals ; Mice ; Mice, Knockout ; Male ; Mice, Inbred C57BL ; Maze Learning

Altered c-Fos expression following alcohol intake in discrete brain regions of galanin 3 receptor knockout mice.

Autoren: Genders SG O'Shea R Brunner S et al.

Quelle: Behavioural brain research [Behav Brain Res] 2025 Jul 26; Vol. 490, pp. 115640. Date of Electronic Publication: 2025 May 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

MeSH-Schlagworte: Proto-Oncogene Proteins c-fos*/metabolism , Brain*/metabolism , Brain*/drug effects , Ethanol*/blood , Ethanol*/administration & dosage , Ethanol*/pharmacology , Receptor, Galanin, Type 3*/genetics , Receptor, Galanin, Type 3*/deficiency , Receptor, Galanin, Type 3*/metabolism , Alcohol Drinking*/genetics , Alcohol Drinking*/metabolism , Alcohol Drinking*/pathology, Animals ; Mice, Knockout ; Mice ; Male ; Mice, Inbred C57BL ; Neurons/metabolism ; Neurons/drug effects ; Central Nervous System Depressants/blood ; Central Nervous System Depressants/pharmacology ; Central Nervous System Depressants/administration & dosage

Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions.

Autoren: Sánchez-Varo R López-Salas A Beltran-Casanueva R et al.

Quelle: Behavioral and brain functions : BBF [Behav Brain Funct] 2024 Mar 28; Vol. 20 (1), pp. 6. Date of Electronic Publication: 2024 Mar 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101245751 Publication Model: Electronic Cited Medium: Internet ISSN: 1744-9081 (Electronic) Linking ISSN: 17449081 NLM ISO Abbreviation: Behav Brain Funct Subsets: MEDLINE

MeSH-Schlagworte: Receptor, Galanin, Type 2*/agonists , Receptor, Galanin, Type 2*/physiology , Cognitive Dysfunction*/drug therapy, Rats ; Animals ; Receptors, Neuropeptide Y ; Galanin/pharmacology ; Neurogenesis ; Cognition

Cortical spreading depolarization is a potential target for rat brain excitability modulation by Galanin.

Autoren: Gimeno-Ferrer F Eitner A Bauer R et al.

Quelle: Experimental neurology [Exp Neurol] 2023 Dec; Vol. 370, pp. 114569. Date of Electronic Publication: 2023 Oct 10.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/pharmacology , Galanin*/metabolism , Receptor, Galanin, Type 2*, Rats ; Animals ; Brain/metabolism ; Receptors, Galanin/metabolism

Development of a HiBiT Peptide-Based NanoBRET Ligand Binding Assay for Galanin Receptor 1 in Live Cells.

Autoren: Zhu H Daly HC Yang TG et al.

Quelle: ACS chemical biology [ACS Chem Biol] 2025 Jul 18; Vol. 20 (7), pp. 1594-1608. Date of Electronic Publication: 2025 Jul 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/metabolism , Galanin*/chemistry , Bioluminescence Resonance Energy Transfer Techniques*/methods , Peptides*/chemistry , Peptides*/metabolism, Humans ; Ligands ; Protein Binding ; HEK293 Cells ; Boron Compounds/chemistry ; Animals ; Fluorescent Dyes/chemistry

Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients.

Autoren: Kiezun J Godlewski J Krazinski BE et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 29; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/genetics , Receptor, Galanin, Type 2*/genetics , Receptor, Galanin, Type 2*/metabolism, Receptor, Galanin, Type 1/*metabolism , Receptor, Galanin, Type 3/*metabolism, Female ; Humans ; Male ; RNA, Messenger/metabolism ; Receptors, Galanin/genetics ; Receptors, Galanin/metabolism

A galanin-positive population of lumbar spinal cord neurons modulates sexual arousal and copulatory behavior in male mice.

Autoren: Lenschow C Mendes ARP Ferreira L et al.

Quelle: Nature communications [Nat Commun] 2025 Sep 23; Vol. 16 (1), pp. 8282. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/metabolism , Spinal Cord*/physiology , Spinal Cord*/cytology , Spinal Cord*/metabolism , Copulation*/physiology , Sexual Arousal* , Neurons*/metabolism , Neurons*/physiology , Sexual Behavior, Animal*/physiology, Animals ; Male ; Ejaculation/physiology ; Mice ; Motor Neurons/physiology ; Motor Neurons/metabolism ; Mice, Inbred C57BL

Involvement of galanin in reproduction of male tilapia, Oreochromis mossambicus.

Autoren: Biradar A Ganesh CB

Quelle: Fish physiology and biochemistry [Fish Physiol Biochem] 2025 Jun 26; Vol. 51 (4), pp. 117. Date of Electronic Publication: 2025 Jun 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 100955049 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-5168 (Electronic) Linking ISSN: 09201742 NLM ISO Abbreviation: Fish Physiol Biochem Subsets: MEDLINE

MeSH-Schlagworte: Tilapia*/physiology , Galanin*/pharmacology , Reproduction*/drug effects , Reproduction*/physiology, Animals ; Male ; Testis/drug effects ; Testis/metabolism ; Spermatogenesis/drug effects ; Testosterone/analogs & derivatives ; Testosterone/metabolism ; Receptors, Androgen/metabolism ; Luteinizing Hormone/blood ; Gonadotropin-Releasing Hormone/metabolism

Detection of galanin receptors in the spinal cord in experimental autoimmune encephalomyelitis.

Autoren: Michalickova D Kramarikova I Ozturk HK et al.

Quelle: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia [Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub] 2023 Mar; Vol. 167 (1), pp. 36-42. Date of Electronic Publication: 2022 Feb 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Vydavatelství Univerzity Palackého Country of Publication: Czech Republic NLM ID: 101140142 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1804-7521 (Electronic) Linking ISSN: 12138118 NLM ISO Abbreviation: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Subsets: MEDLINE

MeSH-Schlagworte: Galanin*/genetics , Galanin*/metabolism , Encephalomyelitis, Autoimmune, Experimental*, Mice ; Animals ; Receptors, Galanin/genetics ; Receptors, Galanin/metabolism ; Endothelial Cells ; Receptor, Galanin, Type 2/genetics ; Receptor, Galanin, Type 2/metabolism ; RNA, Messenger/metabolism ; Spinal Cord/metabolism

Advancing colorectal cancer diagnosis: The role of tumor-derived serum galanin and haptoglobin as novel biomarkers.

Autoren: Yuan N Ren R Li D et al.

Quelle: Journal of cancer research and therapeutics [J Cancer Res Ther] 2025 May 01; Vol. 21 (2), pp. 417-424. Date of Electronic Publication: 2025 May 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Medknow Publications Country of Publication: India NLM ID: 101249598 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-4138 (Electronic) Linking ISSN: 19984138 NLM ISO Abbreviation: J Cancer Res Ther Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/blood , Colorectal Neoplasms*/diagnosis , Colorectal Neoplasms*/pathology , Biomarkers, Tumor*/blood , Haptoglobins*/analysis , Haptoglobins*/metabolism , Galanin*/blood, Humans ; Female ; Male ; Middle Aged ; ROC Curve ; Aged ; Case-Control Studies ; Adult ; Carcinoembryonic Antigen/blood ; Prognosis ; Neoplasm Staging ; CA-19-9 Antigen/blood