Suchergebnisse - "GUIDANCE"

Plexin-B1 safeguards astrocyte agility and glial alignment to facilitate wound corralling and axon pathfinding in mouse spinal cord injury model.

Autoren: Ni H Zhou Z Estill M et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 18; Vol. 16 (1), pp. 10098. Date of Electronic Publication: 2025 Nov 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Spinal Cord Injuries*/metabolism , Spinal Cord Injuries*/pathology , Spinal Cord Injuries*/physiopathology , Spinal Cord Injuries*/genetics , Astrocytes*/metabolism , Astrocytes*/pathology , Astrocytes*/physiology , Axons*/metabolism , Axons*/physiology , Nerve Tissue Proteins*/metabolism , Nerve Tissue Proteins*/genetics , Receptors, Cell Surface*/metabolism , Receptors, Cell Surface*/genetics , Axon Guidance*/physiology, Animals ; Mice ; Disease Models, Animal ; Mice, Inbred C57BL ; Female ; Mice, Knockout ; Neuroglia/metabolism

Functional role for Cas cytoplasmic adaptor proteins during cortical axon pathfinding.

Autoren: Estep JA Treptow AM Rao PA et al.

Quelle: PLoS genetics [PLoS Genet] 2025 Nov 07; Vol. 21 (11), pp. e1011941. Date of Electronic Publication: 2025 Nov 07 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

MeSH-Schlagworte: Axons*/metabolism , Axons*/physiology , Axon Guidance*/genetics , Cerebral Cortex*/metabolism , Cerebral Cortex*/growth & development, Animals ; Mice ; Integrin beta1/genetics ; Integrin beta1/metabolism ; Mice, Knockout ; Neurons/metabolism ; Thalamus/metabolism ; Thalamus/growth & development ; White Matter/metabolism ; White Matter/growth & development ; Axon Fasciculation/genetics

ECM-Mimetic Nanofibrous Scaffolds for Stimulation of Dorsal Root Ganglia Axon Guidance and Schwann Cell Maturation.

Autoren: Antonova OY Kochetkova OY Taylakov ME et al.

Quelle: ACS applied bio materials [ACS Appl Bio Mater] 2025 Oct 20; Vol. 8 (10), pp. 9480-9495. Date of Electronic Publication: 2025 Sep 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ACS Publications Country of Publication: United States NLM ID: 101729147 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2576-6422 (Electronic) Linking ISSN: 25766422 NLM ISO Abbreviation: ACS Appl Bio Mater Subsets: MEDLINE

MeSH-Schlagworte: Ganglia, Spinal*/cytology , Ganglia, Spinal*/drug effects , Nanofibers*/chemistry , Schwann Cells*/cytology , Schwann Cells*/drug effects , Tissue Scaffolds*/chemistry , Extracellular Matrix*/chemistry , Biocompatible Materials*/chemistry , Biocompatible Materials*/pharmacology , Biocompatible Materials*/chemical synthesis , Axon Guidance*/drug effects , Biomimetic Materials*/chemistry , Biomimetic Materials*/pharmacology, Animals ; Rats ; Materials Testing ; Cells, Cultured ; Particle Size ; Nerve Regeneration/drug effects

Axon guidance cue SLIT2 regulates the murine skeletal stem cell niche through sympathetic innervation.

Autoren: Wu Z Li N Luo Z et al.

Quelle: The Journal of clinical investigation [J Clin Invest] 2025 Oct 15; Vol. 135 (20). Date of Electronic Publication: 2025 Oct 15 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

MeSH-Schlagworte: Nerve Tissue Proteins*/genetics , Nerve Tissue Proteins*/metabolism , Nerve Tissue Proteins*/physiology , Sympathetic Nervous System*/metabolism , Intercellular Signaling Peptides and Proteins*/genetics , Intercellular Signaling Peptides and Proteins*/metabolism , Intercellular Signaling Peptides and Proteins*/physiology , Stem Cell Niche* , Axon Guidance*, Animals ; Slit Homolog 2 Protein ; Mice ; Follistatin-Related Proteins/genetics ; Follistatin-Related Proteins/metabolism ; Osteogenesis ; Mice, Knockout ; Bone Diseases, Metabolic/genetics ; Bone Diseases, Metabolic/metabolism ; Bone Diseases, Metabolic/pathology

Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae.

Autoren: Takagi S Takano S Kubo T et al.

Quelle: ELife [Elife] 2025 Sep 25; Vol. 13. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Axon Guidance* , Frizzled Receptors*/metabolism , Frizzled Receptors*/genetics , Wnt Signaling Pathway* , Drosophila melanogaster*/physiology , Drosophila*/physiology , Signal Transduction* , Wnt Proteins*/metabolism, Animals ; Larva/physiology ; Locomotion ; Axons/physiology

Steering Axon Development: Glial Cell Mechanisms in Drosophila .

Autoren: Long K Huang E Yuan Y et al.

Quelle: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Sep 17; Vol. 16 (18), pp. 3438-3449. Date of Electronic Publication: 2025 Sep 07.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Neuroglia*/physiology , Axons*/physiology , Neurogenesis*/physiology , Axon Guidance*/physiology, Animals ; Drosophila melanogaster ; Drosophila

An axon guidance-related microRNA panel identifies perivascular plexus local recurrence following curative surgery in patients with pancreatic cancer.

Autoren: Nishiwada S Nakamura K Ozu N et al.

Quelle: Journal of gastroenterology [J Gastroenterol] 2025 Sep; Vol. 60 (9), pp. 1174-1189. Date of Electronic Publication: 2025 May 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/genetics , Pancreatic Neoplasms*/surgery , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/genetics , Neoplasm Recurrence, Local*/genetics , Neoplasm Recurrence, Local*/diagnosis , Carcinoma, Pancreatic Ductal*/surgery , Carcinoma, Pancreatic Ductal*/pathology , Carcinoma, Pancreatic Ductal*/genetics , Axon Guidance*/genetics, Humans ; Male ; Female ; Middle Aged ; Biomarkers, Tumor/genetics ; Aged ; Cohort Studies ; Risk Assessment/methods

Mex3a-dependent post-transcriptional silencing ensures olfactory receptor diversity and axon guidance specificity.

Autoren: Duffié R Shayya H Escamilla Del Arenal M et al.

Quelle: Cell reports [Cell Rep] 2025 Aug 26; Vol. 44 (8), pp. 115979. Date of Electronic Publication: 2025 Jul 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Olfactory Receptor Neurons*/metabolism , Receptors, Odorant*/metabolism , Receptors, Odorant*/genetics , Axon Guidance*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Axons*/metabolism , Gene Silencing*, Animals ; Mice ; Endoplasmic Reticulum Stress ; Olfactory Bulb/metabolism

3D-printed plugs enhance cell usage efficiency for single-cell migration and neuron axon guidance assays.

Autoren: Cheng J Rock EC Rao M et al.

Quelle: Cell reports methods [Cell Rep Methods] 2025 Aug 18; Vol. 5 (8), pp. 101117. Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918227360606676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2667-2375 (Electronic) Linking ISSN: 26672375 NLM ISO Abbreviation: Cell Rep Methods Subsets: MEDLINE

MeSH-Schlagworte: Printing, Three-Dimensional* , Neurons*/cytology , Single-Cell Analysis*/methods , Axon Guidance*/physiology , Cell Movement*, Animals ; Humans ; Microfluidics/methods

Direct and Indirect Downstream Pathways That Regulate Repulsive Guidance Effects of FGF3 on Developing Thalamocortical Axons.

Autoren: Li K Li J Chen Q et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 30; Vol. 26 (15). Date of Electronic Publication: 2025 Jul 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Thalamus*/metabolism , Thalamus*/embryology , Thalamus*/cytology , Axons*/metabolism , Axon Guidance* , Fibroblast Growth Factor 3*/metabolism , Cerebral Cortex*/metabolism , Cerebral Cortex*/embryology, Animals ; Signal Transduction ; Mice

Phosphoproteomics Profiling Reveals Key Proteins Involved in Neuroinflammation and Impaired Axon Guidance Induced by Bilirubin Deficiency.

Autoren: Chen M Wu C Cui Y et al.

Quelle: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Jul 16; Vol. 16 (14), pp. 2602-2616. Date of Electronic Publication: 2025 Jul 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Bilirubin*/deficiency , Bilirubin*/metabolism , Axon Guidance*/physiology , Neuroinflammatory Diseases*/metabolism, Animals ; Proteomics/methods ; Mice ; Mice, Knockout ; Phosphorylation ; Brain/metabolism ; Signal Transduction/physiology ; Mice, Inbred C57BL ; Male ; Oxidoreductases Acting on CH-CH Group Donors

A Framework for Residency Application Support: The Impact of a Mandatory Career Advising and Professional Development Course.

Autoren: Rodriguez AL Aldana S Llado A et al.

Quelle: Southern medical journal [South Med J] 2025 Sep; Vol. 118 (9), pp. 628-633.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Southern Medical Association Country of Publication: United States NLM ID: 0404522 Publication Model: Print Cited Medium: Internet ISSN: 1541-8243 (Electronic) Linking ISSN: 00384348 NLM ISO Abbreviation: South Med J Subsets: MEDLINE

MeSH-Schlagworte: Internship and Residency*/methods , Vocational Guidance*/methods , Students, Medical*/psychology , Job Application*, Humans ; Curriculum ; Surveys and Questionnaires ; Florida ; Male ; Female

Novel insights into the mechanisms of growth cone dynamics during axon pathfinding.

Autoren: Pérez-Ferrer I Herrera E

Quelle: Current opinion in neurobiology [Curr Opin Neurobiol] 2025 Aug; Vol. 93, pp. 103073. Date of Electronic Publication: 2025 Jun 23.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Current Biology Country of Publication: England NLM ID: 9111376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6882 (Electronic) Linking ISSN: 09594388 NLM ISO Abbreviation: Curr Opin Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Growth Cones*/physiology , Axon Guidance*/physiology , Axons*/physiology , Neurons*/physiology , Neurons*/cytology, Animals ; Humans

Midline assembloids reveal regulators of human axon guidance.

Autoren: Onesto MM Amin ND Pan C et al.

Quelle: Science (New York, N.Y.) [Science] 2025 Jul 17; Vol. 389 (6757), pp. 282-289. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

MeSH-Schlagworte: Axon Guidance*/genetics , Axons*/physiology , Body Patterning*/genetics , Organoids*/growth & development , Organoids*/metabolism , Spinal Cord*/embryology , Spinal Cord*/cytology , Polypeptide N-acetylgalactosaminyltransferase*/genetics , Exodeoxyribonucleases*/genetics , Phospholipase D*/genetics, Animals ; Humans ; Mice ; N-Acetylgalactosaminyltransferases/genetics

NeuroD2 Modulates Hippocampal Neuronal Organization and Axon Guidance During Aging.

Autoren: Beker M Bolat B Johnson BS et al.

Quelle: In vivo (Athens, Greece) [In Vivo] 2025 Jul-Aug; Vol. 39 (4), pp. 2050-2065.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8806809 Publication Model: Print Cited Medium: Internet ISSN: 1791-7549 (Electronic) Linking ISSN: 0258851X NLM ISO Abbreviation: In Vivo Subsets: MEDLINE

MeSH-Schlagworte: Hippocampus*/metabolism , Hippocampus*/cytology , Aging*/metabolism , Aging*/genetics , Axon Guidance*/genetics , Neurons*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/genetics , Neuropeptides*/metabolism , Neuropeptides*/genetics, Animals ; Mice ; Signal Transduction ; Mice, Inbred C57BL ; Computational Biology/methods ; Male ; Proto-Oncogene Proteins c-akt/metabolism

Calcitriol Modulates Hippocampal Axon Guidance Through Enhanced EfnA4-Mediated PI3K/AKT Signaling in an Autism Mouse Model.

Autoren: Gong T Sun R Bai J et al.

Quelle: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2025 May; Vol. 31 (5), pp. e70429.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

MeSH-Schlagworte: Hippocampus*/drug effects , Hippocampus*/metabolism , Calcitriol*/pharmacology , Calcitriol*/therapeutic use , Autistic Disorder*/drug therapy , Autistic Disorder*/metabolism , Autistic Disorder*/pathology , Axon Guidance*/drug effects , Axon Guidance*/physiology, Animals ; Mice ; Disease Models, Animal ; Signal Transduction/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Male ; Mice, Inbred C57BL ; Autism Spectrum Disorder/drug therapy ; Autism Spectrum Disorder/metabolism

FGF-Mediated Axon Guidance: Role of Downstream Signaling Pathways in Cytoskeletal Control.

Autoren: Li J Gao H Liu F

Quelle: Cells [Cells] 2025 May 25; Vol. 14 (11). Date of Electronic Publication: 2025 May 25.

Publikationsart: Journal Article; Review; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH-Schlagworte: Axon Guidance* , Signal Transduction* , Fibroblast Growth Factors*/metabolism , Cytoskeleton*/metabolism, Humans ; Animals ; Receptors, Fibroblast Growth Factor/metabolism ; Axons/metabolism

Rac1 and Nectin3 are essential for planar cell polarity-directed axon guidance in the peripheral auditory system.

Autoren: Clancy S Xie N Eluvathingal Muttikkal T et al.

Quelle: Development (Cambridge, England) [Development] 2025 Apr 15; Vol. 152 (8). Date of Electronic Publication: 2025 Apr 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH-Schlagworte: Cell Polarity*/physiology , rac1 GTP-Binding Protein*/metabolism , rac1 GTP-Binding Protein*/genetics , Axon Guidance*/physiology , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/genetics , Neuropeptides*/metabolism , Neuropeptides*/genetics, Animals ; Mice ; Spiral Ganglion/metabolism ; Spiral Ganglion/cytology ; Nerve Tissue Proteins/metabolism ; Nerve Tissue Proteins/genetics ; Cochlea/metabolism ; Cochlea/cytology ; Signal Transduction ; Axons/metabolism ; Dishevelled Proteins/metabolism ; Nectins

MYC regulation of the miR-92-Robo1 axis in Slit-mediated commissural axon guidance.

Autoren: Majumder T Khot B Suriyaarachchi H et al.

Quelle: Molecular biology of the cell [Mol Biol Cell] 2025 Apr 01; Vol. 36 (4), pp. ar50. Date of Electronic Publication: 2025 Feb 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/metabolism , MicroRNAs*/genetics , Nerve Tissue Proteins*/metabolism , Nerve Tissue Proteins*/genetics , Receptors, Immunologic*/metabolism , Receptors, Immunologic*/genetics , Axon Guidance*/genetics , Axon Guidance*/physiology , Proto-Oncogene Proteins c-myc*/metabolism , Proto-Oncogene Proteins c-myc*/genetics, Animals ; Roundabout Proteins ; Chick Embryo ; Spinal Cord/metabolism ; Spinal Cord/embryology ; Axons/metabolism ; Chickens ; Gene Expression Regulation, Developmental ; Promoter Regions, Genetic

Expanding ligand-receptor interaction networks for axon guidance: Structural insights into signal crosstalk and specificity.

Autoren: Zhu S Jaworski A Meijers R

Quelle: Current opinion in neurobiology [Curr Opin Neurobiol] 2025 Jun; Vol. 92, pp. 102999. Date of Electronic Publication: 2025 Mar 20.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Current Biology Country of Publication: England NLM ID: 9111376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6882 (Electronic) Linking ISSN: 09594388 NLM ISO Abbreviation: Curr Opin Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Axon Guidance*/physiology , Signal Transduction*/physiology , Axons*/physiology , Receptors, Cell Surface*/metabolism, Animals ; Humans ; Ligands