Výsledky vyhľadávania - "GLYPHOSATE"

Prime Editing of TaEPSPS Homeologs Enhances Wheat Resistance to Glyphosate.

Autori: Chen T Li Y Qiu Z a ďalší

Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Aug 27; Vol. 73 (34), pp. 21516-21525. Date of Electronic Publication: 2025 Aug 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glyphosate*/toxicity , Herbicides*/toxicity , Triticum*/drug effects , Triticum*/genetics , Triticum*/metabolism , Herbicide Resistance*/genetics , 3-Phosphoshikimate 1-Carboxyvinyltransferase*/antagonists & inhibitors , 3-Phosphoshikimate 1-Carboxyvinyltransferase*/genetics , Breeding*/methods , Plant Proteins*/antagonists & inhibitors , Plant Proteins*/genetics, Amino Acid Substitution/genetics ; Shikimic Acid/metabolism ; Shikimic Acid/analogs & derivatives ; Gene Editing ; Dose-Response Relationship, Drug ; Eleusine/drug effects ; Eleusine/genetics ; Proline/genetics ; Serine/genetics

Types of Pesticides Interaction in Mixtures: Results of Inhibitory Assay.

Autori: Esimbekova EN Satir DV Kratasyuk VA

Zdroj: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2025 Apr; Vol. 521 (1), pp. 267-271. Date of Electronic Publication: 2025 Apr 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pleiades Publishing Country of Publication: United States NLM ID: 101126895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1608-3091 (Electronic) Linking ISSN: 16076729 NLM ISO Abbreviation: Dokl Biochem Biophys Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pesticides*/chemistry , Pesticides*/pharmacology , Enzyme Assays* , FMN Reductase*/antagonists & inhibitors , Luciferases, Firefly*/antagonists & inhibitors , Glyphosate*/chemistry , Glyphosate*/pharmacology , Luminescent Measurements*/methods, Luminescence ; Inhibitory Concentration 50 ; Copper/chemistry ; Copper/pharmacology

Improved Analysis of Glyphosate, Aminomethylphosphonic Acid, and Other Highly Polar Pesticides and Metabolites via the QuPPe Method by Employing Ethylenediaminetetraacetic Acid and IC-MS/MS.

Autori: Schäfer AK Vetter W Anastassiades M

Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Jan 29; Vol. 73 (4), pp. 2645-2652. Date of Electronic Publication: 2025 Jan 15.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glyphosate*/analysis , Glyphosate*/metabolism , Pesticides*/analysis , Pesticides*/metabolism , Edetic Acid*/chemistry , Tandem Mass Spectrometry*/instrumentation , Tandem Mass Spectrometry*/methods , Chromatography, Ion Exchange*/instrumentation , Chromatography, Ion Exchange*/methods , Milk*/chemistry , Food Analysis*/instrumentation , Food Analysis*/methods, Animals ; Cattle ; Organophosphates/analysis ; Organophosphates/metabolism ; Cations/isolation & purification ; Calcium/isolation & purification ; Iron/isolation & purification ; Organophosphonates

Dual-Mode Detection of Glyphosate Based on DNAzyme-Mediated Click Chemistry and DNAzyme-Regulated CeO 2 Peroxidase-like Activity.

Autori: Li Q Hao Z Zhang C a ďalší

Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Mar 26; Vol. 73 (12), pp. 7496-7503. Date of Electronic Publication: 2025 Mar 17.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Click Chemistry*/methods , Glyphosate*/analysis , DNA, Catalytic*/antagonists & inhibitors , DNA, Catalytic*/chemistry , Cerium*/chemistry , Biosensing Techniques* , Peroxidase*/antagonists & inhibitors , Peroxidase*/chemistry , Pesticide Residues*/analysis, Fluorescence ; Colorimetry/methods ; Copper ; Catalytic Domain ; Benzidines/chemistry ; Water/analysis ; Glycine max/chemistry

Acute glyphosate and aminomethylphosphonic acid (AMPA), its major metabolite, impaired spatial orientation, navigation, learning and/or memory in female rats.

Autori: Chávez-Reyes J López-Lariz CH Acosta-Cruz MA a ďalší

Zdroj: Behavioural brain research [Behav Brain Res] 2025 Feb 26; Vol. 478, pp. 115329. Date of Electronic Publication: 2024 Nov 08.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glyphosate* , Glycine*/analogs & derivatives , Glycine*/pharmacology , Rats, Sprague-Dawley* , Maze Learning*/drug effects , Spatial Navigation*/drug effects , Spatial Navigation*/physiology , Herbicides*/toxicity, Animals ; Female ; Orientation, Spatial/drug effects ; Rats ; Organophosphonates/pharmacology ; Dose-Response Relationship, Drug ; Memory/drug effects ; Spatial Memory/drug effects ; Spatial Learning/drug effects ; Memory Disorders/chemically induced ; Memory Disorders/metabolism ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/metabolism ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/pharmacology

Achieving ultrasensitive detection of glyphosate in fruits and vegetables using a triple-mode strategy based on carbon dots nanozymes derived from expired drugs.

Autori: Wu W Cheng HL Huang YL a ďalší

Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Feb 05; Vol. 326, pp. 125214. Date of Electronic Publication: 2024 Sep 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycine*/analogs & derivatives , Glycine*/analysis , Glycine*/chemistry , Vegetables*/chemistry , Glyphosate* , Carbon*/chemistry , Quantum Dots*/chemistry , Fruit*/chemistry , Limit of Detection* , Spectrometry, Fluorescence*/methods, Colorimetry/methods ; Hydrogen Peroxide/analysis ; Hydrogen Peroxide/chemistry ; Food Contamination/analysis

Detection of glyphosate, glufosinate, and their metabolites in multi-floral honey for food safety.

Autori: Rampazzo G Nobile M Carpino S a ďalší

Zdroj: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2025 Feb; Vol. 42 (2), pp. 213-222. Date of Electronic Publication: 2025 Jan 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101485040 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-0057 (Electronic) Linking ISSN: 19440057 NLM ISO Abbreviation: Food Addit Contam Part A Chem Anal Control Expo Risk Assess Subsets: MEDLINE

Výrazy zo slovníka MeSH: Honey*/analysis , Honey*/statistics & numerical data , Food Contamination*/analysis , Food Contamination*/statistics & numerical data , Glyphosate*/analysis , Herbicides*/analysis, Animals ; Bees ; Italy ; Aminobutyrates

Glyphosate detection based on Eu coordination polymer through competitive coordination.

Autori: Yi L Wu S Ren G a ďalší

Zdroj: Food chemistry [Food Chem] 2025 Jan 15; Vol. 463 (Pt 4), pp. 141554. Date of Electronic Publication: 2024 Oct 05.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glyphosate* , Glycine*/analogs & derivatives , Glycine*/chemistry , Glycine*/analysis , Herbicides*/analysis , Herbicides*/chemistry , Polymers*/chemistry , Europium*/chemistry, Zea mays/chemistry ; Limit of Detection ; Oryza/chemistry ; Food Contamination/analysis ; Glycine max/chemistry ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/chemistry

Molybdenum Disulfide/Diselenide-Laser-Induced Graphene-Glycine Oxidase Composite for Electrochemical Sensing of Glyphosate.

Autori: Zribi R Johnson ZT Ellis G a ďalší

Zdroj: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2025 Jan 08; Vol. 17 (1), pp. 247-259. Date of Electronic Publication: 2024 Dec 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE

Výrazy zo slovníka MeSH: Molybdenum*/chemistry , Graphite*/chemistry , Disulfides*/chemistry , Glycine*/analogs & derivatives , Glycine*/chemistry , Glycine*/analysis , Glyphosate* , Lasers* , Electrochemical Techniques*/methods , Biosensing Techniques*/methods

Fostering rehydration and facilitating bioactive release through cellulose-assisted leaf surface treatment.

Autori: Jiang S Li P Li L a ďalší

Zdroj: Carbohydrate polymers [Carbohydr Polym] 2025 Jan 01; Vol. 347, pp. 122732. Date of Electronic Publication: 2024 Sep 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cellulose*/chemistry , Plant Leaves*/chemistry , Glycine*/chemistry , Glycine*/analogs & derivatives , Herbicides*/chemistry , Glyphosate*, Gossypium/chemistry ; Water/chemistry ; Nanofibers/chemistry ; Adsorption ; Drug Liberation

Glyphosate impairs both structure and function of GABAergic synapses in hippocampal neurons.

Autori: Chiantia G Comai D Hidisoglu E a ďalší

Zdroj: Neuropharmacology [Neuropharmacology] 2025 Jan 01; Vol. 262, pp. 110183. Date of Electronic Publication: 2024 Oct 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycine*/analogs & derivatives , Glycine*/pharmacology , Glyphosate* , Hippocampus*/drug effects , Hippocampus*/metabolism , Synapses*/drug effects , Inhibitory Postsynaptic Potentials*/drug effects , Inhibitory Postsynaptic Potentials*/physiology, Animals ; Mice ; Cells, Cultured ; GABAergic Neurons/drug effects ; GABAergic Neurons/metabolism ; Receptors, GABA-A/metabolism ; Receptors, GABA-A/drug effects ; Herbicides/toxicity ; Patch-Clamp Techniques ; Mice, Inbred C57BL ; Neurons/drug effects ; Neurons/metabolism

Effects of glyphosate on antibiotic resistance in soil bacteria and its potential significance: A review.

Autori: Bearson BL Douglass CH Duke SO a ďalší

Zdroj: Journal of environmental quality [J Environ Qual] 2025 Jan-Feb; Vol. 54 (1), pp. 160-180. Date of Electronic Publication: 2024 Nov 25.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 0330666 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-2537 (Electronic) Linking ISSN: 00472425 NLM ISO Abbreviation: J Environ Qual Subsets: MEDLINE

Výrazy zo slovníka MeSH: Bacteria*/drug effects , Bacteria*/genetics , Drug Resistance, Bacterial*/drug effects , Drug Resistance, Bacterial*/genetics , Glyphosate*/analysis , Glyphosate*/toxicity , Herbicides*/analysis , Herbicides*/toxicity , Soil Microbiology*, Anti-Bacterial Agents/pharmacology ; Soil Pollutants/analysis ; Soil Pollutants/toxicity

Herbicidal interference: glyphosate drives both the ecology and evolution of plant-herbivore interactions.

Autori: Zhang GM Baucom RS

Zdroj: The New phytologist [New Phytol] 2025 Jan; Vol. 245 (2), pp. 807-817. Date of Electronic Publication: 2024 Nov 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley on behalf of New Phytologist Trust Country of Publication: England NLM ID: 9882884 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-8137 (Electronic) Linking ISSN: 0028646X NLM ISO Abbreviation: New Phytol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycine*/analogs & derivatives , Glycine*/pharmacology , Glyphosate* , Herbivory*/drug effects , Herbicides*/pharmacology , Biological Evolution* , Herbicide Resistance*/genetics, Animals ; Ipomoea/drug effects ; Ipomoea/genetics ; Ipomoea/physiology ; Insecta/physiology ; Insecta/drug effects ; Selection, Genetic ; Ecology

Glyphosate losses through various stages of coffee production and consequences for human exposure.

Autori: Bytof G Suesse-Herrmann O Holtmann M a ďalší

Zdroj: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2025 Jan; Vol. 42 (1), pp. 59-74. Date of Electronic Publication: 2024 Nov 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101485040 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-0057 (Electronic) Linking ISSN: 19440057 NLM ISO Abbreviation: Food Addit Contam Part A Chem Anal Control Expo Risk Assess Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycine*/analogs & derivatives , Glycine*/analysis , Glyphosate* , Coffee*/chemistry , Food Contamination*/analysis, Humans ; Herbicides/analysis ; Food Handling

Urinary biomonitoring of exposure to glyphosate and its metabolite amino-methyl phosphonic acid among farmers and non-farmers in Morocco.

Autori: Ben Khadda Z Bungau SG El Balkhi S a ďalší

Zdroj: Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2025 Jan; Vol. 113, pp. 104620. Date of Electronic Publication: 2024 Dec 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9612020 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7077 (Electronic) Linking ISSN: 13826689 NLM ISO Abbreviation: Environ Toxicol Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glyphosate* , Glycine*/analogs & derivatives , Glycine*/urine , Herbicides*/urine , Herbicides*/analysis , Biological Monitoring* , Farmers*, Humans ; Adult ; Male ; Middle Aged ; Female ; Morocco ; Young Adult ; Occupational Exposure/analysis ; Aged ; Adolescent ; Organophosphonates/urine ; Environmental Exposure/analysis ; Isoxazoles ; Tetrazoles

Enhanced biodegradation of glyphosate by Chlorella sorokiniana engineered with exogenous purple acid phosphatase.

Autori: Liu SF Yi ZC Huang ZQ a ďalší

Zdroj: Water research [Water Res] 2025 Jan 01; Vol. 268 (Pt B), pp. 122737. Date of Electronic Publication: 2024 Nov 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 0105072 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2448 (Electronic) Linking ISSN: 00431354 NLM ISO Abbreviation: Water Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Chlorella*/metabolism , Chlorella*/genetics , Acid Phosphatase*/metabolism , Acid Phosphatase*/genetics , Glyphosate* , Biodegradation, Environmental* , Glycine*/analogs & derivatives , Glycine*/metabolism, Water Pollutants, Chemical/metabolism ; Herbicides/metabolism

Effects of environmentally relevant concentrations of glyphosate and aminomethylphosphonic acid on biotransformation and stress response proteins in the liver of zebrafish (Danio rerio).

Autori: Morozov AA Yurchenko VV

Zdroj: Comparative biochemistry and physiology. Part D, Genomics & proteomics [Comp Biochem Physiol Part D Genomics Proteomics] 2025 Mar; Vol. 53, pp. 101366. Date of Electronic Publication: 2024 Nov 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101270611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0407 (Electronic) Linking ISSN: 1744117X NLM ISO Abbreviation: Comp Biochem Physiol Part D Genomics Proteomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Zebrafish*/metabolism , Glyphosate* , Glycine*/analogs & derivatives , Glycine*/pharmacology , Glycine*/toxicity , Organophosphonates*/metabolism , Organophosphonates*/pharmacology , Liver*/metabolism , Liver*/drug effects , Biotransformation* , Herbicides*/pharmacology, Animals ; Zebrafish Proteins/metabolism ; Zebrafish Proteins/genetics ; Water Pollutants, Chemical/toxicity ; Water Pollutants, Chemical/metabolism ; Stress, Physiological/drug effects ; Proteomics

A purine fluorescent derived probe assay for glyphosate and mesotrione via Schiff base cleavage.

Autori: Tao X Mao Y Wang A a ďalší

Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Feb 05; Vol. 326, pp. 125254. Date of Electronic Publication: 2024 Oct 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glyphosate* , Schiff Bases*/chemistry , Glycine*/analogs & derivatives , Glycine*/chemistry , Glycine*/analysis , Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Cyclohexanones*/chemistry , Spectrometry, Fluorescence*, Purines/chemistry ; Purines/analysis ; Humans ; Limit of Detection ; Herbicides/analysis ; Herbicides/chemistry

Color and fluorescence orthogonal dual-functional visual turn-on sensing for acidic and alkaline glyphosate and additive.

Autori: Wang K Ma HN Song JX a ďalší

Zdroj: Food chemistry [Food Chem] 2025 Feb 01; Vol. 464 (Pt 3), pp. 141816. Date of Electronic Publication: 2024 Oct 28.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycine*/analogs & derivatives , Glycine*/chemistry , Glycine*/analysis , Glyphosate* , Herbicides*/chemistry , Herbicides*/analysis, Hydrogen-Ion Concentration ; Spectrometry, Fluorescence ; Fluorescence ; Color ; Porphyrins/chemistry

Non-invasive recording of heartbeats in Danio rerio and Daphnia magna to assess the toxicity of imidacloprid and glyphosate.

Autori: Krylov VV Lukyanov TF Korzhevina VI a ďalší

Zdroj: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2025 Feb; Vol. 288, pp. 110075. Date of Electronic Publication: 2024 Nov 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 100959500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-0456 (Print) Linking ISSN: 15320456 NLM ISO Abbreviation: Comp Biochem Physiol C Toxicol Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Zebrafish*/physiology , Daphnia*/drug effects , Glyphosate* , Heart Rate*/drug effects , Neonicotinoids*/toxicity , Glycine*/analogs & derivatives , Glycine*/toxicity , Nitro Compounds*/toxicity, Animals ; Water Pollutants, Chemical/toxicity ; Herbicides/toxicity ; Toxicity Tests/methods ; Insecticides/toxicity ; Embryo, Nonmammalian/drug effects ; Dose-Response Relationship, Drug ; Daphnia magna