Suchergebnisse - "GENETICS of rheumatoid arthritis"

Ever‐Expanding Connections Between Peptidylarginine Deiminase 4 and Rheumatoid Arthritis.

Autoren: Shelef, Miriam A. Holers, V. Michael

Quelle: Arthritis & Rheumatology. Sep2025, Vol. 77 Issue 9, p1136-1139. 4p.

Schlagwörter: *RHEUMATOID arthritis risk factors, *GENETICS of rheumatoid arthritis, *HYDROLASES, *DISEASE exacerbation, *RISK assessment, *SERIAL publications, *MONOCYTES, *RHEUMATOID arthritis, *AUTOANTIBODIES, *MONOCLONAL antibodies, *GENETIC risk score, *BIOMARKERS, *CHEMICAL inhibitors

Recognition of Glycine Versus Nonglycine Citrulline Motifs Dictating the HLA Class II Association of Anticitrullinated Protein Antibodies: Insights From Autoantibody Profiling of 6,900 Scandinavian Patients With Rheumatoid Arthritis.

Autoren: Mathsson Alm, Linda Westerlind, Helga Gehring, Isabel et al.

Quelle: Arthritis & Rheumatology. Sep2025, Vol. 77 Issue 9, p1179-1193. 15p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *CROSS-sectional method, *DATA analysis, *RESEARCH funding, *AUTOANTIBODIES, *SMOKING, *RHEUMATOID arthritis, *KRUSKAL-Wallis Test, *FISHER exact test, *LOGISTIC regression analysis, *MANN Whitney U Test, *MULTIVARIATE analysis, *DESCRIPTIVE statistics, *IMMUNOENZYME technique, *MONOCLONAL antibodies, *ANTIGENS, *ODDS ratio, *GLYCINE, *AMINO acids, *STATISTICS, *SCANDINAVIANS, *DATA analysis software, *CONFIDENCE intervals, *GENOTYPES, *ALLELES, *SINGLE nucleotide polymorphisms

Geografische Kategorien: SCANDINAVIA

Cytotoxic Response of CD4⁺ T Cells Orchestrated by SLAMF4 in Rheumatoid Arthritis.

Autoren: Lacaud, Mégane Bouzidi, Houda‐Ghozlane Petit, Mylène et al.

Quelle: Arthritis & Rheumatology. Jul2025, Vol. 77 Issue 7, p827-841. 15p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *FLOW cytometry, *T cells, *RHEUMATOID arthritis, *SYNOVIAL fluid, *DESCRIPTIVE statistics, *MEMBRANE glycoproteins, *DATA analysis software, *SEQUENCE analysis, *CELL receptors

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction.

Autoren: Paldino, Giorgia Tedeschi, Valentina Proganò, Valentina et al.

Quelle: Arthritis & Rheumatology. Jul2025, Vol. 77 Issue 7, p854-866. 13p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *CROSS-sectional method, *FLOW cytometry, *IMMUNOPHENOTYPING, *CHEMOKINES, *PSORIATIC arthritis, *T cells, *GENOME-wide association studies, *KILLER cells, *ANKYLOSIS, *RHEUMATOID arthritis, *SCIENTIFIC observation, *POLYMERASE chain reaction, *KRUSKAL-Wallis Test, *CELL motility, *MANN Whitney U Test, *DESCRIPTIVE statistics, *FLUORESCENT antibody technique, *DNA damage, *GENE expression profiling, *SPONDYLOARTHROPATHIES, *TELOMERES, *DATA analysis software, *COMPARATIVE studies, *PHENOTYPES, *SEQUENCE analysis, *REGRESSION analysis, *IMMUNOCOMPETENCE

Geografische Kategorien: ITALY

Genome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis.

Autoren: Spiliopoulou, Athina Iakovliev, Andrii Plant, Darren et al.

Quelle: Arthritis & Rheumatology. Jul2025, Vol. 77 Issue 7, p817-826. 10p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *BIOLOGICAL models, *GENOMICS, *DATA analysis, *RESEARCH funding, *RHEUMATOID arthritis, *BLOOD proteins, *MENDELIAN randomization, *MULTIVARIATE analysis, *DESCRIPTIVE statistics, *GENE expression, *MICE, *GENETIC variation, *GENES, *BIOINFORMATICS, *PROTEOMICS, *ANIMAL experimentation, *PROGRAMMED cell death 1 receptors, *IMMUNOLOGIC receptors, *GENE expression profiling, *STATISTICS, *DISEASE susceptibility, *INFLAMMATION, *IMMUNE checkpoint proteins, *SEQUENCE analysis, *SINGLE nucleotide polymorphisms, *BIOMARKERS, *HLA-B27 antigen, *DNA-binding proteins, *IMMUNITY

Firma/Körperschaft: UK Biobank Ltd.

Genetically-determined variation in CRP impacts disease activity assessment in rheumatoid arthritis.

Autoren: Riley, Thomas R Wheeler, Austin M Cannon, Grant W et al.

Quelle: Rheumatology. Jun2025, Vol. 64 Issue 6, p3921-3928. 8p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *RESEARCH funding, *RHEUMATOID arthritis, *SCIENTIFIC observation, *SEVERITY of illness index, *DESCRIPTIVE statistics, *LONGITUDINAL method, *CONFIDENCE intervals, *C-reactive protein, *SINGLE nucleotide polymorphisms, *ALLELES, *REGRESSION analysis

Geografische Kategorien: UNITED Kingdom

Firma/Körperschaft: UK Biobank Ltd.

Substitution of Glutamic Acid at Position 71 of DRβ1*04:01 and Collagen‐Specific Tolerance Without Alloreactivity.

Autoren: Jha, Vibha Freed, Brian M. Sunderhaus, Elizabeth R. et al.

Quelle: Arthritis & Rheumatology. May2025, Vol. 77 Issue 5, p526-535. 10p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *T cells, *RESEARCH funding, *CELL proliferation, *IN vivo studies, *GLUTAMIC acid, *ANTIGENS, *GENE expression, *MICE, *CELL lines, *GENOME editing, *ANIMAL experimentation, *GENETIC techniques, *COLLAGEN, *ALLELES

Genetic susceptibility to rheumatoid arthritis: a meta-analysis of interleukin-10 and protein tyrosine phosphatase non-receptor type 22 gene variants.

Autoren: Stephen, Sharon Benita P, Senthil Wankhar, Dapkupar et al.

Quelle: Egyptian Rheumatology & Rehabilitation; 10/26/2025, Vol. 52 Issue 1, p1-11, 11p

Schlagwörter: RHEUMATOID arthritis risk factors, GENETICS of rheumatoid arthritis, RISK assessment, MEDICAL information storage & retrieval systems, STATISTICAL power analysis, META-analysis, DESCRIPTIVE statistics, ESTERASES, GENETIC variation, SYSTEMATIC reviews, MEDLINE, ODDS ratio, DISEASE susceptibility, ONLINE information services, CONFIDENCE intervals, DATA analysis software, INTERLEUKINS, SINGLE nucleotide polymorphisms, ALLELES, GENOTYPES, PUBLICATION bias, REGRESSION analysis

Mitochondrial Control of Proteasomal Psmb5 Drives the Differentiation of Tissue‐Resident Memory T Cells in Patients with Rheumatoid Arthritis.

Autoren: Wu, Tong Su, Danhua Zhang, Lei et al.

Quelle: Arthritis & Rheumatology. Dec2024, Vol. 76 Issue 12, p1743-1757. 15p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *MITOCHONDRIA, *T cells, *CARRIER proteins, *RHEUMATOID arthritis, *POLYMERASE chain reaction, *IMMUNOLOGIC memory, *TRANSCRIPTION factors, *GENE expression, *PROTEOLYTIC enzymes, *SUCCINYLCHOLINE, *CELL differentiation, *INFLAMMATION, *PRECIPITIN tests

Evaluation of IL-32 rs28372698 and IL-37 rs3811047 polymorphisms and their serum levels in rheumatoid arthritis patients.

Autoren: Abdo, Marwa Elmaghraby, Ahmed Abdelraouf, Fatma H. et al.

Quelle: Egyptian Rheumatology & Rehabilitation; 9/26/2025, Vol. 52 Issue 1, p1-10, 10p

Schlagwörter: GENETICS of rheumatoid arthritis, ADRENOCORTICAL hormones, DATA analysis, RECEIVER operating characteristic curves, RHEUMATOID arthritis, ENZYME-linked immunosorbent assay, POLYMERASE chain reaction, FISHER exact test, CHI-squared test, MANN Whitney U Test, STATISTICS, CASE-control method, RESEARCH, COMPARATIVE studies, DATA analysis software, CONFIDENCE intervals, INTERLEUKINS, SINGLE nucleotide polymorphisms, GENOTYPES

CASP5 gene expression and plasma levels in rheumatoid arthritis: correlation with disease activity.

Autoren: Fouda, Mona El-Toukhy Khashaba, Rana Atef Ibrahim, Noha Hosni et al.

Quelle: Egyptian Rheumatology & Rehabilitation; 8/7/2025, Vol. 52 Issue 1, p1-11, 11p

Schlagwörter: RHEUMATOID arthritis risk factors, GENETICS of rheumatoid arthritis, RISK assessment, CROSS-sectional method, DATA analysis, RECEIVER operating characteristic curves, AUTOANTIBODIES, POLYMERASE chain reaction, FISHER exact test, KRUSKAL-Wallis Test, LOGISTIC regression analysis, BLOOD sedimentation, DESCRIPTIVE statistics, CHI-squared test, GENE expression, EGYPTIANS, CASE-control method, STATISTICS, DISEASE susceptibility, CLINICS, MOLECULAR biology, DATA analysis software, CASPASES, BIOMARKERS, C-reactive protein

Geografische Kategorien: EGYPT

Cytotoxic Response of CD4⁺ T Cells Orchestrated by SLAMF4 in Rheumatoid Arthritis.

Autoren: Lacaud, Mégane Bouzidi, Houda‐Ghozlane Petit, Mylène et al.

Quelle: Arthritis & Rheumatology; Jul2025, Vol. 77 Issue 7, p827-841, 15p

Schlagwörter: GENETICS of rheumatoid arthritis, FLOW cytometry, T cells, RHEUMATOID arthritis, SYNOVIAL fluid, DESCRIPTIVE statistics, MEMBRANE glycoproteins, DATA analysis software, SEQUENCE analysis, CELL receptors

Causal relationship between rheumatoid arthritis and carpal tunnel syndrome: a bidirectional two-sample Mendelian randomization study.

Autoren: Gong, Chen Zhao, Diqian Wen, Xu et al.

Quelle: Journal of Orthopaedic Surgery & Research. 9/30/2024, Vol. 19 Issue 1, p1-11. 11p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *RISK assessment, *RESEARCH funding, *RHEUMATOID arthritis, *DESCRIPTIVE statistics, *ODDS ratio, *ATTRIBUTION (Social psychology), *CONFIDENCE intervals, *CARPAL tunnel syndrome, *GENOMES, *SENSITIVITY & specificity (Statistics), *SINGLE nucleotide polymorphisms, *DISEASE risk factors, *DISEASE complications

Role of Recombinant Proteins for Treating Rheumatoid Arthritis.

Autoren: Sasani, Mahboubeh Soleimani Moradi, Yeganeh

Quelle: Avicenna Journal of Medical Biotechnology. Jul-Sep2024, Vol. 16 Issue 3, p137-145. 9p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *ANTI-inflammatory agents, *T cells, *RHEUMATOID arthritis, *ANTIRHEUMATIC agents, *CELLULAR signal transduction, *GENE expression, *RECOMBINANT proteins, *AUTOIMMUNE diseases, *QUALITY of life, *CYTOKINES, *CELL receptors, *BIOMARKERS, *INTERLEUKINS, *DISEASE progression

Iron, copper, zinc and magnesium on rheumatoid arthritis: a two-sample Mendelian randomization study.

Autoren: Yang, Mingyi Su, Yani Xu, Ke et al.

Quelle: International Journal of Environmental Health Research. Jul2024, Vol. 34 Issue 7, p2776-2789. 14p.

Schlagwörter: *RHEUMATOID arthritis risk factors, *GENETICS of rheumatoid arthritis, *IRON, *IRON in the body, *RISK assessment, *MAGNESIUM, *FOOD consumption, *COPPER, *ZINC, *MICRONUTRIENTS, *ODDS ratio, *ATTRIBUTION (Social psychology), *INFLAMMATION, *CONFIDENCE intervals, *EPIDEMIOLOGICAL research, *SENSITIVITY & specificity (Statistics), *RELIABILITY (Personality trait)

Epigenetic Regulatory Axis MIR22‐TET3‐MTRNR2L2 Represses Fibroblast‐Like Synoviocyte–Mediated Inflammation in Rheumatoid Arthritis.

Autoren: Fang, Yilong Huang, Wei Zhu, Xiangling et al.

Quelle: Arthritis & Rheumatology. Jun2024, Vol. 76 Issue 6, p845-856. 12p.

Schlagwörter: *INFLAMMATION prevention, *GENETICS of rheumatoid arthritis, *BIOLOGICAL models, *IN vitro studies, *SYNOVIAL membranes, *RESEARCH funding, *EPIGENOMICS, *MICRORNA, *RHEUMATOID arthritis, *POLYMERASE chain reaction, *IN vivo studies, *FIBROBLASTS, *MICE, *IMMUNOHISTOCHEMISTRY, *BIOINFORMATICS, *GENE expression profiling, *ANIMAL experimentation, *FLUORESCENCE in situ hybridization, *WESTERN immunoblotting, *ARTHRITIS, *PRECIPITIN tests

Anti‐Inflammatory Effect of High‐Density Lipoprotein Blunted by Delivery of Altered MicroRNA Cargo in Patients With Rheumatoid Arthritis.

Autoren: Wu, Qiong Sheng, Quanhu Michell, Danielle et al.

Quelle: Arthritis & Rheumatology. May2024, Vol. 76 Issue 5, p684-695. 12p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *HIGH density lipoproteins, *MACROPHAGES, *RHEUMATOID arthritis, *MICRORNA, *POLYMERASE chain reaction, *ENZYME-linked immunosorbent assay, *SYMPTOMS, *CASE-control method, *INFLAMMATION, *CORONARY artery disease, *INTERLEUKINS, *SEQUENCE analysis

Characterization of Genetic Landscape and Novel Inflammatory Biomarkers in Patients With Adult‐Onset Still's Disease.

Autoren: Topping, Joanne Chang, Leon Nadat, Fatima et al.

Quelle: Arthritis & Rheumatology; May2025, Vol. 77 Issue 5, p582-595, 14p

Schlagwörter: RHEUMATOID arthritis diagnosis, PROTEIN metabolism, GENETICS of rheumatoid arthritis, RESEARCH funding, RHEUMATOID arthritis, PROBABILITY theory, DESCRIPTIVE statistics, GENETIC variation, RNA, INTERFERONS, HEMATOPOIESIS, GENE expression profiling, INFLAMMATION, CYTOKINES, BIOMARKERS, SEQUENCE analysis, INTERLEUKINS

Adult-Onset Still's Disease (AOSD): Advances in Understanding Pathophysiology, Genetics and Emerging Treatment Options.

Autoren: Bindoli, Sara Baggio, Chiara Doria, Andrea et al.

Quelle: Drugs. Mar2024, Vol. 84 Issue 3, p257-274. 18p.

Schlagwörter: *BIOTHERAPY, *GENETICS of rheumatoid arthritis, *THERAPEUTIC use of monoclonal antibodies, *RHEUMATOID arthritis, *ANTIRHEUMATIC agents, *DRUG efficacy, *DISEASE progression, *INTERLEUKINS, *GLUCOCORTICOIDS, *CHEMICAL inhibitors, *SYMPTOMS

METTL14‐Mediated m6A Modification of TNFAIP3 Involved in Inflammation in Patients With Active Rheumatoid Arthritis.

Autoren: Tang, Jifeng Yu, Ziqing Xia, Jinfang et al.

Quelle: Arthritis & Rheumatology. Dec2023, Vol. 75 Issue 12, p2116-2129. 14p.

Schlagwörter: *GENETICS of rheumatoid arthritis, *DISEASE progression, *CYTOKINES, *INTERLEUKINS, *IN vitro studies, *SEQUENCE analysis, *MONONUCLEAR leukocytes, *IN vivo studies, *METHYLTRANSFERASES, *ANIMAL experimentation, *WESTERN immunoblotting, *PROTEOLYTIC enzymes, *RNA, *PRECIPITIN tests, *NF-kappa B, *COMPARATIVE studies, *CELLULAR signal transduction, *RHEUMATOID arthritis, *RESEARCH funding, *ENZYME-linked immunosorbent assay, *TUMOR necrosis factors, *MESSENGER RNA, *ADENOSINES, *POLYMERASE chain reaction, *MICE