Suchergebnisse - "GABAERGIC neurons"

Dendritic synaptome of calcium-binding protein containing GABAergic interneurons in the mouse primary visual cortex.

Autoren: Talapka P Kocsis Z Marsi LD et al.

Quelle: Frontiers in neural circuits [Front Neural Circuits] 2025 Oct 08; Vol. 19, pp. 1644572. Date of Electronic Publication: 2025 Oct 08 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477940 Publication Model: eCollection Cited Medium: Internet ISSN: 1662-5110 (Electronic) Linking ISSN: 16625110 NLM ISO Abbreviation: Front Neural Circuits Subsets: MEDLINE

MeSH-Schlagworte: Interneurons*/metabolism , Interneurons*/ultrastructure , Dendrites*/metabolism , Dendrites*/ultrastructure , Synapses*/ultrastructure , Synapses*/metabolism , GABAergic Neurons*/metabolism , GABAergic Neurons*/ultrastructure , Primary Visual Cortex*/metabolism , Primary Visual Cortex*/ultrastructure , Calcium-Binding Proteins*/metabolism, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Presynaptic Terminals/ultrastructure ; Presynaptic Terminals/metabolism ; Female ; Parvalbumins/metabolism ; Calbindin 2/metabolism

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis-Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis.

Autoren: He R Wu B Han L et al.

Quelle: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Oct; Vol. 12 (39), pp. e04406. Date of Electronic Publication: 2025 Jul 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

MeSH-Schlagworte: Sepsis*/complications , Sepsis*/metabolism , Necroptosis*/physiology , Necroptosis*/drug effects , GABAergic Neurons*/metabolism , GABAergic Neurons*/pathology , Astrocytes*/metabolism , Receptors, Adrenergic, alpha-2*/metabolism , Cardiomyopathies*/metabolism , Cardiomyopathies*/etiology, Animals ; Mice ; Male ; Spinal Cord/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; Dexmedetomidine/pharmacology

Cocaine and Morphine Converge to Disrupt Chloride Homeostasis in Ventral Tegmental Area GABA Neurons.

Autoren: Pearson AC Kimmey BA Taormina MB et al.

Quelle: Addiction biology [Addict Biol] 2025 Dec; Vol. 30 (12), pp. e70104.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9604935 Publication Model: Print Cited Medium: Internet ISSN: 1369-1600 (Electronic) Linking ISSN: 13556215 NLM ISO Abbreviation: Addict Biol Subsets: MEDLINE

MeSH-Schlagworte: Ventral Tegmental Area*/drug effects , Ventral Tegmental Area*/metabolism , Morphine*/pharmacology , Cocaine*/pharmacology , GABAergic Neurons*/drug effects , GABAergic Neurons*/metabolism , Chlorides*/metabolism , Dopamine Uptake Inhibitors*/pharmacology, Animals ; Homeostasis/drug effects ; Rats ; Male ; K Cl- Cotransporters ; Symporters/drug effects ; Symporters/metabolism ; Self Administration ; Rats, Sprague-Dawley ; Receptors, Dopamine D1/drug effects

Complex opioid-driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward, and addiction.

Autoren: Chittajallu R Vlachos A Caccavano AP et al.

Quelle: ELife [Elife] 2025 Dec 01; Vol. 14. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Reward* , Synaptic Transmission*/drug effects , Cholinergic Neurons*/physiology , Cholinergic Neurons*/metabolism , Cholinergic Neurons*/drug effects , Analgesics, Opioid*/pharmacology , Analgesics, Opioid*/metabolism , Emotions* , Receptors, Opioid, mu*/metabolism , GABAergic Neurons*/physiology , GABAergic Neurons*/drug effects , Glutamic Acid*/metabolism , Habenula*/physiology , Habenula*/drug effects , Interpeduncular Nucleus*/physiology , Interpeduncular Nucleus*/drug effects, Animals ; Mice ; Male ; Mice, Inbred C57BL

D1-type dopamine receptors are critical for GABAergic synaptic plasticity in CA1 mouse hippocampal SST interneurons and pyramidal cells.

Autoren: Brzdąk P Lebida K Droździel P et al.

Quelle: Progress in neurobiology [Prog Neurobiol] 2025 Dec; Vol. 255, pp. 102845. Date of Electronic Publication: 2025 Nov 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 0370121 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5118 (Electronic) Linking ISSN: 03010082 NLM ISO Abbreviation: Prog Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Interneurons*/physiology , Interneurons*/drug effects , Interneurons*/metabolism , Receptors, Dopamine D1*/metabolism , Receptors, Dopamine D1*/physiology , Neuronal Plasticity*/physiology , Neuronal Plasticity*/drug effects , Pyramidal Cells*/physiology , Pyramidal Cells*/drug effects , Pyramidal Cells*/metabolism , CA1 Region, Hippocampal*/physiology , CA1 Region, Hippocampal*/drug effects , CA1 Region, Hippocampal*/metabolism , CA1 Region, Hippocampal*/cytology , GABAergic Neurons*/physiology , GABAergic Neurons*/drug effects, Animals ; Mice ; Mice, Inbred C57BL ; Male ; Somatostatin/metabolism ; Synapses/physiology ; Synapses/drug effects

Necl-4/CADM4 regulates GABAergic synaptic strength on GABAergic inhibitory neurons via ErbB4 activation and prevents neuronal impairments.

Autoren: Komaki R Shiotani H Kuriu T et al.

Quelle: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 15943-15968. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Receptor, ErbB-4*/metabolism , GABAergic Neurons*/metabolism , GABAergic Neurons*/pathology , Synapses*/metabolism , Neural Inhibition*, Animals ; Hippocampus/metabolism ; Hippocampus/pathology ; Mice, Knockout ; Mice, Inbred C57BL ; Mice ; Cells, Cultured ; Cell Death ; gamma-Aminobutyric Acid/metabolism

The psychoactive compound ibogaine sex-dependently alters the firing rate and afterhyperpolarization of I h -negative neurons in the mouse ventral tegmental area.

Autoren: Eliasen JN Rezagholizadeh A Jacobsen HP et al.

Quelle: Neuroscience [Neuroscience] 2025 Nov 28; Vol. 589, pp. 308-321. Date of Electronic Publication: 2025 Oct 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

MeSH-Schlagworte: Ventral Tegmental Area*/drug effects , Ventral Tegmental Area*/physiology , Ibogaine*/pharmacology , Action Potentials*/drug effects , GABAergic Neurons*/drug effects , GABAergic Neurons*/physiology , Sex Characteristics* , Hallucinogens*/pharmacology , Neurons*/drug effects , Neurons*/physiology, Animals ; Male ; Female ; Mice ; Mice, Inbred C57BL ; Excitatory Postsynaptic Potentials/drug effects ; Membrane Potentials/drug effects

Ventral tegmental area GABA neurons integrate positive and negative valence.

Autoren: Stelzner ME Wolff AR Saunders BT

Quelle: Nature communications [Nat Commun] 2025 Nov 24; Vol. 16 (1), pp. 10357. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Ventral Tegmental Area*/physiology , Ventral Tegmental Area*/cytology , GABAergic Neurons*/physiology , GABAergic Neurons*/metabolism, Animals ; Reward ; Dopaminergic Neurons/physiology ; Dopaminergic Neurons/metabolism ; Male ; Rats ; Optogenetics ; Motivation/physiology ; Dopamine/metabolism ; Behavior, Animal/physiology ; Decision Making/physiology ; Rats, Long-Evans

Selective vulnerability of GABAergic neurons in chronic migraine.

Autoren: Hossain KH Chuong T Abad E et al.

Quelle: The journal of headache and pain [J Headache Pain] 2025 Nov 20; Vol. 26 (1), pp. 266. Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE

MeSH-Schlagworte: Migraine Disorders*/chemically induced , Migraine Disorders*/pathology , Migraine Disorders*/metabolism , Migraine Disorders*/physiopathology , GABAergic Neurons*/pathology , GABAergic Neurons*/metabolism , Brain*/pathology , Brain*/metabolism, Animals ; Male ; Female ; Mice ; Disease Models, Animal ; Nitroglycerin/toxicity ; Mice, Inbred C57BL ; Chronic Disease ; Hyperalgesia/physiopathology

The ever-increasing heterogeneity of GABA neurons in the control of energy homeostasis.

Autoren: Harkany T Fenselau H

Quelle: Neuron [Neuron] 2025 Nov 19; Vol. 113 (22), pp. 3689-3691.

Publikationsart: Journal Article; Comment

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

MeSH-Schlagworte: Energy Metabolism*/physiology , Homeostasis*/physiology , Neurons*/physiology , GABAergic Neurons*/physiology , GABAergic Neurons*/metabolism , Arcuate Nucleus of Hypothalamus*/cytology , Arcuate Nucleus of Hypothalamus*/metabolism , gamma-Aminobutyric Acid*/metabolism, Animals ; Humans

Identification of a neural basis for energy expenditure in the mouse arcuate hypothalamus.

Autoren: Wang T Han S Wang Y et al.

Quelle: Neuron [Neuron] 2025 Nov 19; Vol. 113 (22), pp. 3813-3833.e9. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

MeSH-Schlagworte: Energy Metabolism*/physiology , Arcuate Nucleus of Hypothalamus*/metabolism , Arcuate Nucleus of Hypothalamus*/physiology , GABAergic Neurons*/physiology , GABAergic Neurons*/metabolism, Animals ; Mice ; Male ; Obesity/metabolism ; Obesity/physiopathology ; Thermogenesis/physiology ; Mice, Inbred C57BL

Whole-brain mapping of monosynaptic afferents to GABAergic neurons in the sublaterodorsal tegmental nucleus of mice.

Autoren: Zhong ZG Tang SQ Ben H et al.

Quelle: Zoological research [Zool Res] 2025 Nov 18; Vol. 46 (6), pp. 1501-1515.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Science Press Country of Publication: China NLM ID: 101697192 Publication Model: Print Cited Medium: Internet ISSN: 2095-8137 (Print) Linking ISSN: 20958137 NLM ISO Abbreviation: Zool Res Subsets: MEDLINE

MeSH-Schlagworte: GABAergic Neurons*/physiology , Brain Mapping* , Tegmentum Mesencephali*/physiology, Animals ; Mice ; Male

Cannabinoid type 1 receptors in the mice prefrontal cortex regulate object location memory acquisition via GABAergic neurons.

Autoren: Tokutake T Yokose J Yano Y et al.

Quelle: Behavioral and brain functions : BBF [Behav Brain Funct] 2025 Nov 04; Vol. 21 (1), pp. 36. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101245751 Publication Model: Electronic Cited Medium: Internet ISSN: 1744-9081 (Electronic) Linking ISSN: 17449081 NLM ISO Abbreviation: Behav Brain Funct Subsets: MEDLINE

MeSH-Schlagworte: Prefrontal Cortex*/metabolism , Prefrontal Cortex*/drug effects , Prefrontal Cortex*/physiology , Receptor, Cannabinoid, CB1*/metabolism , Receptor, Cannabinoid, CB1*/agonists , GABAergic Neurons*/metabolism , GABAergic Neurons*/drug effects , GABAergic Neurons*/physiology , Memory*/drug effects , Memory*/physiology, Animals ; Male ; Mice, Inbred C57BL ; Mice ; Arachidonic Acids/pharmacology ; Recognition, Psychology/drug effects ; Recognition, Psychology/physiology ; Cannabinoid Receptor Agonists/pharmacology ; gamma-Aminobutyric Acid/metabolism

Bringing Chandelier Cells Out of the Shadows: Exploring the Development of a Unique Neuron Type in the Brain.

Autoren: Lenherr C Neves G de Oliveira MG et al.

Quelle: Cold Spring Harbor perspectives in biology [Cold Spring Harb Perspect Biol] 2025 Nov 03; Vol. 17 (11). Date of Electronic Publication: 2025 Nov 03.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 101513680 Publication Model: Electronic Cited Medium: Internet ISSN: 1943-0264 (Electronic) Linking ISSN: 19430264 NLM ISO Abbreviation: Cold Spring Harb Perspect Biol Subsets: MEDLINE

MeSH-Schlagworte: Brain*/cytology , Brain*/growth & development , Interneurons*/physiology , Interneurons*/cytology , GABAergic Neurons*/physiology , GABAergic Neurons*/cytology , Neurons*/physiology, Animals ; Humans

Colorectal cancer cells hijack a brain-gut polysynaptic circuit from the lateral septum to enteric neurons to sustain tumor growth.

Autoren: Li Y Yu H Li ZM et al.

Quelle: Nature cancer [Nat Cancer] 2025 Nov; Vol. 6 (11), pp. 1800-1820. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/physiopathology , Enteric Nervous System*/pathology , Enteric Nervous System*/metabolism , GABAergic Neurons*/metabolism , GABAergic Neurons*/pathology, Animals ; Mice ; Humans ; Cholinergic Neurons/metabolism ; Cholinergic Neurons/pathology ; Stress, Psychological ; Cell Line, Tumor ; Synapses/metabolism ; Tumor Microenvironment ; Female ; Receptors, GABA-A/metabolism ; Male ; gamma-Aminobutyric Acid/metabolism

Transcriptomic and spatial organization of telencephalic GABAergic neurons.

Autoren: van Velthoven CTJ Gao Y Kunst M et al.

Quelle: Nature [Nature] 2025 Nov; Vol. 647 (8088), pp. 143-156. Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

MeSH-Schlagworte: GABAergic Neurons*/metabolism , GABAergic Neurons*/cytology , GABAergic Neurons*/classification , Telencephalon*/cytology , Telencephalon*/embryology , Telencephalon*/growth & development , Telencephalon*/metabolism , Transcriptome*/genetics, Animals ; Mice ; Female ; Single-Cell Analysis ; Male ; Mice, Inbred C57BL ; Gene Expression Profiling

Interpeduncular GABAergic neuron function controls threat processing and innate defensive adaptive learning.

Autoren: Williams EW Snively L O'Meara BR et al.

Quelle: Molecular psychiatry [Mol Psychiatry] 2025 Nov; Vol. 30 (11), pp. 5427-5436. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

MeSH-Schlagworte: GABAergic Neurons*/physiology , GABAergic Neurons*/metabolism, Animals ; Mice ; Male ; Fear/physiology ; Mice, Inbred C57BL ; Optogenetics/methods ; Anxiety/physiopathology ; Anxiety/metabolism ; Avoidance Learning/physiology ; Somatostatin/metabolism ; Learning/physiology ; Mesencephalon/physiology ; Mesencephalon/metabolism

Altered Inhibitory Synaptic Transmission and Changes in GABAergic Markers in the Hippocampus of Genetic and Environmental Animal Model of Autism.

Autoren: Jurkovičová-Tarabová B Vargovič P Mihalj D et al.

Quelle: Neurochemical research [Neurochem Res] 2025 Oct 30; Vol. 50 (6), pp. 340. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

MeSH-Schlagworte: Hippocampus*/metabolism , Hippocampus*/physiopathology , Autistic Disorder*/genetics , Autistic Disorder*/metabolism , Autistic Disorder*/physiopathology , Synaptic Transmission*/physiology , GABAergic Neurons*/metabolism , gamma-Aminobutyric Acid*/metabolism, Animals ; Disease Models, Animal ; Female ; Inhibitory Postsynaptic Potentials/physiology ; Valproic Acid/toxicity ; Mice ; Male ; Pregnancy ; Rats ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Tissue Proteins/genetics ; Prenatal Exposure Delayed Effects ; Rats, Sprague-Dawley ; Microfilament Proteins

epDevAtlas: mapping GABAergic cells and microglia in the early postnatal mouse brain.

Autoren: Liwang JK Kronman FN Pi HJ et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 29; Vol. 16 (1), pp. 9538. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Microglia*/metabolism , Microglia*/cytology , GABAergic Neurons*/metabolism , GABAergic Neurons*/cytology , Brain*/growth & development , Brain*/cytology , Brain*/metabolism , Brain Mapping*/methods, Animals ; Mice ; Mice, Transgenic ; Animals, Newborn ; Male ; Female ; Somatostatin/metabolism ; Interneurons/metabolism ; Interneurons/cytology ; White Matter/growth & development ; White Matter/cytology ; Vasoactive Intestinal Peptide/metabolism ; Gray Matter/growth & development ; Gray Matter/cytology ; Gray Matter/metabolism ; Mice, Inbred C57BL ; Imaging, Three-Dimensional

GABAergic circuits reflect different requirements for sensory integration in postnatal mouse neocortex.

Autoren: Ghezzi F Baruchin LJ Ha NT et al.

Quelle: Cell reports [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116299. Date of Electronic Publication: 2025 Sep 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Neocortex*/physiology , Neocortex*/metabolism , GABAergic Neurons*/metabolism , GABAergic Neurons*/physiology, Animals ; Mice ; Somatosensory Cortex/physiology ; Somatosensory Cortex/metabolism ; Interneurons/metabolism ; Interneurons/physiology ; Somatostatin/metabolism ; Animals, Newborn ; Female ; Mice, Inbred C57BL