Výsledky vyhledávání - "GABA-A/metabolism"

TSPO PET Identifies Different Anti-inflammatory Minocycline Treatment Response in Two Rodent Models of Epileptogenesis

Autoři: B Laura N Langer Jens P. Bankstahl Tobias L. Ross a další

Zdroj: Neurotherapeutics

Témata: Male, Epilepsy, Receptors, GABA-A/metabolism [MeSH], Neuroinflammation, Epilepsy/drug therapy [MeSH], Rats, Sprague-Dawley [MeSH], Epilepsy/diagnostic imaging [MeSH], Carrier Proteins/metabolism [MeSH], PET, Original Article, Minocycline/metabolism [MeSH], Positron-Emission Tomography/methods [MeSH], Male [MeSH], Disease Models, Animal [MeSH], Anti-Inflammatory Agents/metabolism [MeSH], Female [MeSH], Minocycline/therapeutic use [MeSH], Brain/diagnostic imaging [MeSH], Epilepsy/metabolism [MeSH], translocator protein, Brain/drug effects [MeSH], Treatment Outcome [MeSH], Rats [MeSH], minocycline, Animals [MeSH], Mice [MeSH], Brain/metabolism [MeSH], Radiopharmaceuticals/metabolism [MeSH], Anti-Inflammatory Agents/therapeutic use [MeSH], epileptogenesis, Anti-Inflammatory Agents, Brain, Minocycline, Receptors, GABA-A, Rats, 3. Good health, Rats, Sprague-Dawley, Disease Models, Animal, Mice, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, Positron-Emission Tomography, Animals, Female, Radiopharmaceuticals, Carrier Proteins

Přístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s13311-020-00834-5.pdf
https://pubmed.ncbi.nlm.nih.gov/31970667
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609777
https://pubmed.ncbi.nlm.nih.gov/31970667/
https://elib.tiho-hannover.de/receive/tiho_mods_00002117
https://link.springer.com/article/10.1007/s13311-020-00834-5
https://link.springer.com/content/pdf/10.1007/s13311-020-00834-5.pdf
https://repository.publisso.de/resource/frl:6470852

Phasic, nonsynaptic GABA-A receptor-mediated inhibition entrains thalamocortical oscillations.

Autoři: Rovó, Z. Mátyás, F. Barthó, P. a další

Témata: Animals, Cerebral Cortex/physiology, Dependovirus/genetics, Excitatory Amino Acid Antagonists/pharmacology, GABA Antagonists/pharmacology, Inhibitory Postsynaptic Potentials/drug effects, Inhibitory Postsynaptic Potentials/genetics, Mice, Inbred C57BL, Transgenic, Neural Inhibition/physiology, Neurons/physiology, Pyridazines/pharmacology, Receptors, GABA-A/genetics, GABA-A/metabolism, Synapses/drug effects, Synapses/genetics, Thalamus/physiology, Vesicular Glutamate Transport Protein 2/metabolism, gamma-Aminobutyric Acid/metabolism

Popis souboru: application/pdf

Relation: The Journal of Neuroscience; https://iris.unil.ch/handle/iris/42291; serval:BIB_32020D0588AB; 000336895200011

Dostupnost: https://iris.unil.ch/handle/iris/42291
https://doi.org/10.1523/JNEUROSCI.4386-13.2014

Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum.

Autoři: Levivier, M. Gash, D.M. Przedborski, S.

Témata: Adenosine/analogs & derivatives, Adenosine/metabolism, Animals, Autoradiography, Benzazepines/metabolism, Brain Diseases/chemically induced, Brain Diseases/prevention & control, Corpus Striatum/drug effects, Corpus Striatum/embryology, Electron Transport Complex IV/metabolism, Fetal Tissue Transplantation, Isoquinolines/metabolism, Male, Nerve Tissue/transplantation, Phenethylamines/metabolism, Quinolinic Acid/pharmacology, Rats, Wistar, Receptors, Dopamine D1/metabolism, GABA-A/metabolism, Purinergic P1/metabolism, Time Factors

Relation: Neuroscience; https://iris.unil.ch/handle/iris/208595; serval:BIB_98FD8CF2F30A; A1995RW40100002; 8637631

Dostupnost: https://iris.unil.ch/handle/iris/208595
https://doi.org/10.1016/0306-4522(95)00230-G

Expression of the GABAA receptor associated protein Gec1 is circadian and dependent upon the cellular clock machinery in GnRH secreting GnV-3 cells.

Autoři: Mansuy, V. Risold, P.Y. Glauser, M. a další

Témata: Animals, Biological Clocks/drug effects, Biological Clocks/genetics, Carrier Proteins/genetics, Carrier Proteins/metabolism, Cell Membrane/drug effects, Cell Membrane/metabolism, Cells, Cultured, Circadian Rhythm/drug effects, Circadian Rhythm/genetics, Forskolin/pharmacology, Gene Expression Regulation/drug effects, Gonadotropin-Releasing Hormone/secretion, Horses, Intracellular Signaling Peptides and Proteins/genetics, Intracellular Signaling Peptides and Proteins/metabolism, Neurons/cytology, Neurons/drug effects, RNA, Messenger/genetics, Messenger/metabolism, Rats, Receptors, GABA-A/metabolism, Serum

Relation: Molecular and Cellular Endocrinology; 1872-8057[electronic]; https://iris.unil.ch/handle/iris/201821; serval:BIB_9A6DC27952B0; 000267837400009

Dostupnost: https://iris.unil.ch/handle/iris/201821
https://doi.org/10.1016/j.mce.2009.02.029

Gamma oscillations in V1 are correlated with GABA(A) receptor density: A multi-modal MEG and Flumazenil-PET study.

Autoři: Kujala, J. Jung, J. Bouvard, S. a další

Témata: Adult, Female, Flumazenil/chemistry, Humans, Magnetic Resonance Imaging, Magnetoencephalography, Male, Positron-Emission Tomography, Receptors, GABA-A/metabolism, Visual Cortex/metabolism, gamma-Aminobutyric Acid/metabolism

Popis souboru: application/pdf

Relation: Scientific Reports; https://iris.unil.ch/handle/iris/153671; serval:BIB_BB277D188C2B; 000364788900001

Dostupnost: https://iris.unil.ch/handle/iris/153671
https://doi.org/10.1038/srep16347

Ex vivo characterization of neuroinflammatory and neuroreceptor changes during epileptogenesis using candidate positron emission tomography biomarkers

Autoři: András Polyák Thibault Gendron Tobias L. Ross a další

Přispěvatelé: András Polyák Thibault Gendron Tobias L. Ross a další

Zdroj: Epilepsia. 60:2325-2333

Témata: Epilepsy/diagnostic imaging, Epilepsy/metabolism, glutamate receptor, Physique, chimie, mathématiques & sciences de la terre, microglia, Biomarkers/metabolism, Sciences de la santé humaine, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Physical, chemical, mathematical & earth Sciences, Chimie, Animals, Human health sciences, Epilepsy, astroglia, Receptors, GABA-A/metabolism, Receptors, Glutamate/metabolism, GABAA receptor, Radiologie, médecine & imagerie nucléaire, Positron-Emission Tomography/methods, Receptors, GABA-A, Rats, 3. Good health, Chemistry, Neurology, Receptors, Glutamate, Inflammation Mediators/metabolism, Positron-Emission Tomography, epilepsy, Female, Neurology (clinical), Inflammation Mediators, Biomarkers, Radiology, nuclear medicine & imaging

Přístupová URL adresa: https://discovery.ucl.ac.uk/10084215/1/Arstad_AAM_20190828_Pilocarpine%20timeline_revised.pdf
https://pubmed.ncbi.nlm.nih.gov/31571210
https://www.ncbi.nlm.nih.gov/pubmed/31571210
https://pubmed.ncbi.nlm.nih.gov/31571210/
https://elib.tiho-hannover.de/receive/tiho_mods_00002021
https://onlinelibrary.wiley.com/doi/full/10.1111/epi.16353
https://discovery-pp.ucl.ac.uk/id/eprint/10084215/

Structure–Function Evaluation of Imidazopyridine Derivatives Selective for δ-Subunit-Containing γ-Aminobutyric Acid Type A (GABAA) Receptors

Autoři: Kirsten Yakoub Sascha Jung Christian Sattler a další

Zdroj: Journal of Medicinal Chemistry. 61:1951-1968

Témata: Pyridines, Imidazoles, GABA-A/metabolism, Receptors, GABA-A, 01 natural sciences, 0104 chemical sciences, 3. Good health, Inhibitory Concentration 50, Protein Subunits, Structure-Activity Relationship, Pyridines/chemistry, Imidazoles/chemistry, Receptors, Humans, Protein Subunits/metabolism, GABA-A Receptor Antagonists, GABA-A Receptor Antagonists/chemistry

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/29451785
https://pubsdc3.acs.org/doi/abs/10.1021/acs.jmedchem.7b01484
https://www.ncbi.nlm.nih.gov/pubmed/29451785
https://pubmed.ncbi.nlm.nih.gov/29451785/
https://pure.mpg.de/pubman/faces/ViewItemOverviewPage.jsp?itemId=item_2570424
https://pubs.acs.org/doi/10.1021/acs.jmedchem.7b01484
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.7b01484

Non-linear GABAA receptors promote synaptic inhibition in developing neurons

Autoři: Kirmse, Knut

Zdroj: http://lobid.org/resources/99370672927306441#!, 474(2):181-183.

Témata: Receptors, GABA-A/metabolism [MeSH], Synapses/metabolism [MeSH], gamma-Aminobutyric Acid/metabolism [MeSH], Neurons/metabolism [MeSH], Human Physiology, Molecular Medicine, Commentary, Cell Biology, Animals [MeSH], Action Potentials/physiology [MeSH], Neurosciences, Hippocampus/metabolism [MeSH]

Relation: https://repository.publisso.de/resource/frl:6446916; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766374/

Dostupnost: https://repository.publisso.de/resource/frl:6446916
https://doi.org/10.1007/s00424-021-02652-w
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766374/

Antidepressant, anticonvulsant and antinociceptive effects of 3′-methoxy-6-methylflavone and 3′-hydroxy-6-methylflavone may involve GABAergic mechanisms

Autoři: Karim, Nasiara Khan, Imran Ahmad, Naveed a další

Zdroj: Pharmacological Reports. 69:1014-1020

Témata: Male, Nociception, 0301 basic medicine, GABA Agents, Dose-Response Relationship, Mice, 03 medical and health sciences, Receptors, Animals, Antidepressive Agents/administration & dosage, Tramadol, Pain Measurement, Analgesics, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, GABA-A/metabolism, Flavones, Receptors, GABA-A, Tramadol/pharmacology, Analgesics/administration & dosage, Antidepressive Agents, Flavones/administration & dosage, 3. Good health, Anticonvulsants/administration & dosage, Anticonvulsants, Drug, Pain Measurement/drug effects

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/28943291
https://link.springer.com/article/10.1016%2Fj.pharep.2017.03.001
http://europepmc.org/abstract/MED/28943291
https://www.sciencedirect.com/science/article/pii/S1734114016302547
https://www.ncbi.nlm.nih.gov/pubmed/28943291

Trafficking patterns of NMDA and GABA A receptors in a Mg 2+ -free cultured hippocampal neuron model of status epilepticus

Autoři: Inja Cho Kyoung Heo Young Hwan Kim a další

Přispěvatelé: Inja Cho Kyoung Heo Young Hwan Kim a další

Zdroj: Epilepsy Research. 136:143-148

Témata: Action Potentials/physiology, Status Epilepticus/pathology, Receptor trafficking, Status Epilepticus/metabolism, Patch-Clamp Techniques, Cells, Action Potentials, Fluorescent Antibody Technique, Hippocampus, Receptors, N-Methyl-D-Aspartate, Rats, Sprague-Dawley, 03 medical and health sciences, Status Epilepticus, 0302 clinical medicine, Low Mg(2+) solution, Receptors, Hippocampus/metabolism, Hippocampus/pathology, Animals, Biotinylation, Status epilepticus, Cells, Cultured, Neurons/metabolism, Neurons, 2. Zero hunger, Cultured, Cell Membrane/metabolism, Neurons/pathology, Cell Membrane, GABA(A) receptor, NMDA receptor, Receptors, GABA-A, Rats, Protein Transport, Epileptiform activity, Cell Membrane/pathology, GABA-A/metabolism, Sprague-Dawley, N-Methyl-D-Aspartate/metabolism, Magnesium Deficiency

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/28858777
https://www.ncbi.nlm.nih.gov/pubmed/28858777
https://pubmed.ncbi.nlm.nih.gov/28858777/
https://www.sciencedirect.com/science/article/pii/S0920121116302777
http://europepmc.org/abstract/MED/28858777
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160823

Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice

Autoři: Sukjae Joshua Kang Eunjoon Kim Jaehyun Lee a další

Přispěvatelé: Sukjae Joshua Kang Eunjoon Kim Jaehyun Lee a další

Zdroj: Neuropharmacology. 112:104-112

Témata: Gabra2, Male, 0301 basic medicine, Inhibitory Postsynaptic Potentials, Hippocampal/physiology, GABA-A/genetics, Autism Spectrum Disorder, Knockout, Nerve Tissue Proteins, Inbred C57BL, Autism Spectrum Disorder/physiopathology, Mice, 03 medical and health sciences, Spatial memory, Spatial Memory/physiology, Receptors, Nerve Tissue Proteins/genetics, Animals, Nerve Tissue, Maze Learning, Social Behavior, CA1 Region, Hippocampal, Spatial Memory, Mice, Knockout, Neurons, 0303 health sciences, CA1 Region, GABA-A/metabolism, I/E ratio, Autism spectrum disorders, Receptors, GABA-A, 3. Good health, Mice, Inbred C57BL, Shank2, Maze Learning/physiology, Mutation, Proteins/metabolism, Neurons/physiology

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/27544825
https://pubmed.ncbi.nlm.nih.gov/27544825/
https://snucm.elsevierpure.com/en/publications/enhancing-inhibitory-synaptic-function-reverses-spatial-memory-de
https://www.ncbi.nlm.nih.gov/pubmed/27544825
https://edoc.mdc-berlin.de/15944/
http://www.ncbi.nlm.nih.gov/pubmed/27544825
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154316

Ex vivo characterization of neuroinflammatory and neuroreceptor changes during epileptogenesis using candidate positron emission tomography biomarkers.

Autoři: Bascuñana, Pablo Gendron, Thibault Sander, Kerstin a další

Zdroj: Epilepsia, 60 (11), 2325 - 2333 (2019-11)

Témata: GABAA receptor, astroglia, epilepsy, glutamate receptor, microglia, Biomarkers, Inflammation Mediators, Receptors, GABA-A, Receptors, Glutamate, Biomarkers/metabolism, Epilepsy/diagnostic imaging, Epilepsy/metabolism, Inflammation Mediators/metabolism, Positron-Emission Tomography/methods, Receptors, GABA-A/metabolism, Receptors, Glutamate/metabolism, Positron-Emission Tomography, Neurology, Neurology (clinical), Physical, chemical, mathematical & earth Sciences, Chemistry, Human health sciences, Radiology, nuclear medicine & imaging, Physique, chimie, mathématiques & sciences de la terre, Chimie, Sciences de la santé humaine, Radiologie, médecine & imagerie nucléaire

Relation: info:eu-repo/grantAgreement/EC/FP7/602102; https://onlinelibrary.wiley.com/doi/pdf/10.1111/epi.16353; urn:issn:0013-9580; urn:issn:1528-1167

Přístupová URL adresa: https://orbi.uliege.be/handle/2268/304406

Mapping the GRIF-1 Binding Domain of the Kinesin, KIF5C, Substantiates a Role for GRIF-1 as an Adaptor Protein in the Anterograde Trafficking of Cargoes

Autoři: Smith, Miriam Smith, Miriam J. Pozo, Karine a další

Zdroj: Smith, M, Smith, M J, Pozo, K, Brickley, K & Stephenson, F A 2006, 'Mapping the GRIF-1 binding domain of the kinesin, KIF5C, substantiates a role for GRIF-1 as an adaptor protein in the anterograde trafficking of cargoes', Journal of Biological Chemistry, vol. 281, no. 37, pp. 27216-27228. https://doi.org/M600522200 [pii] 10.1074/jbc.M600522200

Témata: 0301 basic medicine, Protein Conformation, Adaptor Protein Complex 1, Amino Acid Motifs, Kinesins, Nerve Tissue Proteins, Cercopithecus aethiops, 03 medical and health sciences, Carrier Proteins/*chemistry/physiology, Two-Hybrid System Techniques, Receptors, Chlorocebus aethiops, Fluorescence Resonance Energy Transfer, Brain/metabolism, Animals, Humans, 0303 health sciences, Receptors, GABA-A/metabolism, Intracellular Signaling Peptides and Proteins, GABA-A/metabolism, Brain, Kinesin/*chemistry, Receptors, GABA-A, Adaptor Protein Complex 1/chemistry, Nerve Tissue Proteins/*chemistry/physiology, COS Cells, Carrier Proteins, Protein Binding

Přístupová URL adresa: http://www.jbc.org/content/281/37/27216.full.pdf
https://pubmed.ncbi.nlm.nih.gov/16835241
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902249384835597
https://www.ncbi.nlm.nih.gov/pubmed/16835241
http://www.jbc.org/content/281/37/27216.full.pdf
https://www.jbc.org/article/S0021-9258(19)34899-9/fulltext
https://www.escholar.manchester.ac.uk/uk-ac-man-scw:215565
https://www.sciencedirect.com/science/article/pii/S0021925819348999
http://www.jbc.org/cgi/reprint/281/37/27216
https://research.manchester.ac.uk/en/publications/e3674d21-11bc-4c20-ac7f-a3281a7e831f
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16835241

Assessment of in vitro pharmacological effect of Neotropical Piperaceae in GABAergic bioassays in relation to plants traditionally used for folk illness by the Yanesha (Peru)

Autoři: Picard, G. Valadeau, C. Albán-Castillo, J. a další

Zdroj: Journal of Ethnopharmacology. 155:1500-1507

Témata: 0301 basic medicine, 0303 health sciences, Epilepsy, GABA-BZD receptor binding, Plant Extracts, Receptors, GABA-A/metabolism, Plant Extracts/pharmacology, Anxiety, Piperaceae, Receptors, GABA-A, 03 medical and health sciences, 4-Aminobutyrate Transaminase/antagonists & inhibitors/metabolism, 4-Aminobutyrate Transaminase, Peru, Biological Assay, Medicine, Traditional, 14. Life underwater, GABA-Transaminase

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/25091465
http://www.sciencedirect.com/science/article/pii/S0378874114005583
https://www.sciencedirect.com/science/article/pii/S0378874114005583
http://www.ncbi.nlm.nih.gov/pubmed/25091465
https://siis.unmsm.edu.pe/en/publications/assessment-of-in-vitro-pharmacological-effect-of-neotropical-pipe-3
https://pubmed.ncbi.nlm.nih.gov/25091465/

Association of antinociceptive action of botulinum toxin type A with GABA-A receptor

Autoři: Drinovac, Višnja Bach-Rojecky, Lidija Lacković, Zdravko

Zdroj: Journal of Neural Transmission. 121:665-669

Témata: Formalin-induced pain, Neurotoxins, Pain, Neuropathic pain, Bicuculline, GABA, Sciatica, 03 medical and health sciences, 0302 clinical medicine, Pain/chemically induced, Formaldehyde, Botulinum toxin type A, Botulinum Toxins, Type A/therapeutic use, Animals, Botulinum Toxins, Type A, Rats, Wistar, Formaldehyde/toxicity, Pain Measurement, Hyperalgesia/drug therapy, c-Fos, Receptors, GABA-A/metabolism, Drug Administration Routes, Neurotoxins/therapeutic use, Proto-Oncogene Proteins c-fos/metabolism, Receptors, GABA-A, Pain/prevention & control, Rats, 3. Good health, Disease Models, Animal, Hyperalgesia, Sciatica/prevention & control, Pain Measurement/drug effects, Proto-Oncogene Proteins c-fos, Bicuculline/pharmacology

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/24420081
http://link.springer.com/article/10.1007/s00702-013-1150-6
https://doi.org/10.1007/s00702-013-1150-6
https://pubmed.ncbi.nlm.nih.gov/24420081/
https://www.ncbi.nlm.nih.gov/pubmed/24420081
https://core.ac.uk/display/33324074
https://www.bib.irb.hr/711115
https://link.springer.com/article/10.1007/s00702-013-1150-6
https://link.springer.com/article/10.1007/s00702-013-1150-6/fulltext.html

Increased GABA-A Receptor Binding and Reduced Connectivity at the Motor Cortex in Children with Hemiplegic Cerebral Palsy: A Multimodal Investigation Using 18F-Fluoroflumazenil PET, Immunohistochemistry, and MR Imaging

Autoři: Eun Sook Park So Ra Oh Chul Hoon Kim a další

Přispěvatelé: Eun Sook Park So Ra Oh Chul Hoon Kim a další

Zdroj: Journal of Nuclear Medicine. 54:1263-1269

Témata: Flumazenil, Male, Adolescent, Hemiplegia, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Receptors, Animals, Humans, Hemiplegia/complications, Cerebral Palsy/physiopathology, Child, cerebral palsy, Positron-Emission Tomography, Motor Cortex/metabolism, Cerebral Palsy/complications, Motor Cortex/diagnostic imaging, Cerebral Palsy, Cerebral Palsy/metabolism, Motor Cortex, Flumazenil/analogs & derivatives, Motor Cortex/physiopathology, Receptors, GABA-A, hemiplegic spastic cerebral palsy, Immunohistochemistry, Magnetic Resonance Imaging, Rats, 3. Good health, Gene Expression Regulation, GABA-A receptor, connectivity, GABA-A/metabolism, Female, Cerebral Palsy/diagnostic imaging, Protein Binding

Přístupová URL adresa: http://jnm.snmjournals.org/content/54/8/1263.full.pdf
https://pubmed.ncbi.nlm.nih.gov/23785171
https://jnm.snmjournals.org/content/54/supplement_2/1263
https://jnm.snmjournals.org/content/54/8/1263.full.pdf
https://pubmed.ncbi.nlm.nih.gov/23785171/
https://europepmc.org/abstract/MED/23785171
https://jnm.snmjournals.org/content/jnumed/54/8/1263.full.pdf
https://www.ncbi.nlm.nih.gov/pubmed/23785171

Reduced Binding Potential of GABA-A/Benzodiazepine Receptors in Individuals at Ultra-high Risk for Psychosis: An [18F]-Fluoroflumazenil Positron Emission Tomography Study

Autoři: Eun Lee Jong Doo Lee Hae Jeong Park a další

Přispěvatelé: Eun Lee Jong Doo Lee Hae Jeong Park a další

Zdroj: Schizophrenia Bulletin. 40:548-557

Témata: Flumazenil, Male, ultra-high, Schizophrenia/metabolism, Hippocampus, Nucleus Accumbens, GABA, 0302 clinical medicine, Receptors, Caudate Nucleus/diagnostic imaging, gamma-Aminobutyric Acid, gamma-Aminobutyric Acid/metabolism, Putamen, Putamen/metabolism, Brain, Brain/metabolism, 3. Good health, risk for psychosis, Flumazenil/metabolism, GABA-A/metabolism, Parahippocampal Gyrus, Female, Hippocampus/diagnostic imaging, Nucleus Accumbens/diagnostic imaging, fluoroflumazenil, Protein Binding, Risk, Adolescent, Parahippocampal Gyrus/diagnostic imaging, Hippocampus/metabolism, Prodromal Symptoms, Parahippocampal Gyrus/metabolism, Young Adult, 03 medical and health sciences, Nucleus Accumbens/metabolism, Humans, caudate, Caudate Nucleus/metabolism, Putamen/diagnostic imaging, Flumazenil/analogs & derivatives, Schizophrenia/diagnostic imaging, Brain/diagnostic imaging, Receptors, GABA-A, schizophrenia, PET, Case-Control Studies, Positron-Emission Tomography, Schizophrenia, Caudate Nucleus

Přístupová URL adresa: https://academic.oup.com/schizophreniabulletin/article-pdf/40/3/548/6913007/sbt052.pdf
https://pubmed.ncbi.nlm.nih.gov/23588475
https://insights.ovid.com/sbull/201405000/00007489-201405000-00013
http://europepmc.org/articles/PMC3984508
https://www.ncbi.nlm.nih.gov/pubmed/23588475
https://mdanderson.elsevierpure.com/en/publications/reduced-binding-potential-of-gaba-abenzodiazepine-receptors-in-in
https://pubmed.ncbi.nlm.nih.gov/23588475/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984508/

Hooked on benzodiazepines: GABAA receptor subtypes and addiction

Autoři: Christian Lüscher Kelly R. Tan Uwe Rudolph

Zdroj: Trends in Neurosciences, Vol. 34, No 4 (2011) pp. 188-97
Trends in neurosciences

Témata: 0301 basic medicine, 616.8, Substance-Related Disorders, Dopamine, Neurons/metabolism, Ventral Tegmental Area/metabolism, Substance-Related Disorders/physiopathology, Benzodiazepines, 03 medical and health sciences, GABA Modulators/adverse effects/metabolism/therapeutic use, Reward, Animals, Humans, Protein Subunits/metabolism, GABA Modulators, Anxiety Disorders/drug therapy, Neurons, 0303 health sciences, Receptors, GABA-A/metabolism, Ventral Tegmental Area, Receptors, GABA-A, Anxiety Disorders, ddc:616.8, Benzodiazepines/adverse effects/metabolism/therapeutic use, 3. Good health, Dopamine/metabolism, Behavior, Addictive, Protein Subunits

Popis souboru: application/pdf

Přístupová URL adresa: https://europepmc.org/articles/pmc4020178?pdf=render
https://pubmed.ncbi.nlm.nih.gov/21353710
http://www.cell.com/trends/neurosciences/fulltext/S0166-2236(11)00005-1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020178
http://europepmc.org/articles/PMC4020178
https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(11)00005-1
https://archive-ouverte.unige.ch/unige:26928
http://www.cell.com/trends/neurosciences/abstract/S0166-2236(11)00005-1
https://archive-ouverte.unige.ch/unige:26928
https://doi.org/10.1016/j.tins.2011.01.004
https://archive-ouverte.unige.ch/unige:26928

HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain

Autoři: Youssef Daali Rahul V. Edwankar Dietmar Benke a další

Přispěvatelé: Youssef Daali Rahul V. Edwankar Dietmar Benke a další

Zdroj: Neuropharmacology
Neuropharmacology, Vol. 60, No 4 (2011) pp. 626-32

Témata: Flumazenil, 0301 basic medicine, Motor Activity/drug effects, 2804 Cellular and Molecular Neuroscience, 10050 Institute of Pharmacology and Toxicology, 610 Medicine & health, Motor Activity, Hyperalgesia/drug therapy/etiology, Benzodiazepines, Mice, 03 medical and health sciences, Neurons/drug effects/metabolism, Animals, GABA-A Receptor Agonists, GABA Modulators, Neuralgia/drug therapy/etiology, Flumazenil/pharmacology, Pain Measurement, Inflammation, Neurons, 0303 health sciences, ddc:617, Dose-Response Relationship, Drug, Sciatic Neuropathy/complications, Receptors, GABA-A/metabolism, Imidazoles, Receptors, GABA-A, GABA Modulators/pharmacology, 3. Good health, 3004 Pharmacology, Inflammation/drug therapy/etiology, Hyperalgesia, 570 Life sciences, biology, Neuralgia, GABA-A Receptor Agonists/pharmacology/therapeutic use, Sciatic Neuropathy, Benzodiazepines/pharmacology/therapeutic use, Imidazoles/pharmacology/therapeutic use, Pain Measurement/drug effects

Popis souboru: application/pdf; emss-51701.pdf - application/pdf

Přístupová URL adresa: https://archive-ouverte.unige.ch/unige:43694/ATTACHMENT01
https://pubmed.ncbi.nlm.nih.gov/21145329
https://archive-ouverte.unige.ch/unige:43694
https://europepmc.org/articles/PMC3566476
https://pubmed.ncbi.nlm.nih.gov/21145329/
https://www.sciencedirect.com/science/article/abs/pii/S0028390810003254
https://core.ac.uk/display/11274104
https://archive-ouverte.unige.ch/unige:43694
https://doi.org/10.1016/j.neuropharm.2010.11.026
https://archive-ouverte.unige.ch/unige:43694
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566476/

Silent Cortical Neuronal Damage in Atherosclerotic Disease of the Major Cerebral Arteries

Autoři: Yamauchi, Hiroshi Nishii, Ryuichi Higashi, Tatsuya a další

Přispěvatelé: Yamauchi, Hiroshi Nishii, Ryuichi Higashi, Tatsuya a další

Zdroj: J Cereb Blood Flow Metab

Témata: GABA-A/drug effects, Flumazenil, Male, Middle Cerebral Artery, positron emission tomography, Neurons/metabolism, Cerebral Arterial Diseases/drug therapy, carotid artery disease, Angiotensin Receptor Antagonists, 03 medical and health sciences, 0302 clinical medicine, benzodiazepine receptor, middle cerebral artery disease, Atherosclerosis/metabolism, Receptors, asymptomatic, Humans, Cerebral Cortex/radionuclide imaging, Cerebral Arterial Diseases/metabolism, Aged, Cerebral Cortex, Neurons, Atherosclerosis/diagnosis, Neurons/pathology, GABA-A/metabolism, Atherosclerosis/drug therapy, Cerebral Arterial Diseases/diagnosis, Middle Aged, Atherosclerosis, Receptors, GABA-A, Internal, Magnetic Resonance Imaging, Angiotensin Receptor Antagonists/therapeutic use, 3. Good health, Cerebral Cortex/metabolism, Positron-Emission Tomography, Regression Analysis, Original Article, Female, Cerebral Arterial Diseases, Carotid Artery, Flumazenil/diagnostic use, Carotid Artery, Internal, Cerebral Cortex/pathology

Popis souboru: application/pdf

Přístupová URL adresa: https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.2010.176
https://pubmed.ncbi.nlm.nih.gov/20877388
http://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/156405/1/jcbfm2010176a.pdf
https://repository.kulib.kyoto-u.ac.jp/dspace/handle/2433/156405
https://journals.sagepub.com/doi/10.1038/jcbfm.2010.176
http://journals.sagepub.com/doi/10.1038/jcbfm.2010.176
https://www.ncbi.nlm.nih.gov/pubmed/20877388
https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.2010.176