Suchergebnisse - "Frontotemporal dementia"

Brain Topology Disruption in Early-Onset Dementia: Review of Current Findings and the Need for Network Resilience Focused Models.

Autoren: Nawani H Sunil SS Jaganathan R et al.

Quelle: Brain and behavior [Brain Behav] 2025 Nov; Vol. 15 (11), pp. e70903.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101570837 Publication Model: Print Cited Medium: Internet ISSN: 2162-3279 (Electronic) NLM ISO Abbreviation: Brain Behav Subsets: MEDLINE

MeSH-Schlagworte: Brain*/physiopathology , Brain*/diagnostic imaging , Brain*/pathology , Frontotemporal Dementia*/physiopathology , Frontotemporal Dementia*/diagnostic imaging , Nerve Net*/physiopathology , Nerve Net*/diagnostic imaging , Alzheimer Disease*/physiopathology , Alzheimer Disease*/diagnostic imaging , Dementia*/physiopathology , Dementia*/diagnostic imaging, Humans ; Diffusion Tensor Imaging ; Magnetic Resonance Imaging ; Age of Onset ; Electroencephalography ; Positron-Emission Tomography

Combining plasma neurofilament light chain and frontotemporal atrophy improves differentiation of bvFTD from primary psychiatric disorders.

Autoren: Coulborn S Roy ARK Sokolowski A et al.

Quelle: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70771.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

MeSH-Schlagworte: Neurofilament Proteins*/blood , Frontotemporal Dementia*/blood , Frontotemporal Dementia*/pathology , Frontotemporal Dementia*/diagnosis , Mental Disorders*/blood , Mental Disorders*/diagnosis , Mental Disorders*/pathology , Mood Disorders*/blood , Mood Disorders*/diagnosis , Mood Disorders*/pathology, Humans ; Male ; Female ; Atrophy/pathology ; Aged ; Middle Aged ; Biomarkers/blood ; Diagnosis, Differential ; Magnetic Resonance Imaging ; Brain/pathology

Changes in the public IgM repertoire and its idiotypic connectivity in Alzheimer's disease and frontotemporal dementia.

Autoren: Pashova-Dimova S Petrov P Karachanak-Yankova S et al.

Quelle: Journal of neuroimmunology [J Neuroimmunol] 2025 Dec 15; Vol. 409, pp. 578775. Date of Electronic Publication: 2025 Oct 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 8109498 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8421 (Electronic) Linking ISSN: 01655728 NLM ISO Abbreviation: J Neuroimmunol Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/blood , Alzheimer Disease*/immunology , Alzheimer Disease*/diagnosis , Frontotemporal Dementia*/blood , Frontotemporal Dementia*/immunology , Frontotemporal Dementia*/diagnosis , Immunoglobulin M*/blood , Immunoglobulin M*/immunology, Humans ; Female ; Male ; Aged ; Middle Aged ; Biomarkers/blood ; Aged, 80 and over ; Immunoglobulin G/blood

From molecular convergence to clinical divergence: Comparative pathogenic mechanisms and therapeutic trajectories in C9orf72-ALS/FTD and myotonic dystrophy.

Autoren: Alberti C Parente V Corti S et al.

Quelle: Neurobiology of disease [Neurobiol Dis] 2025 Dec; Vol. 217, pp. 107192. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

MeSH-Schlagworte: Myotonic Dystrophy*/genetics , Myotonic Dystrophy*/therapy , Myotonic Dystrophy*/pathology , Amyotrophic Lateral Sclerosis*/genetics , Amyotrophic Lateral Sclerosis*/therapy , Amyotrophic Lateral Sclerosis*/pathology , C9orf72 Protein*/genetics , Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/therapy , Frontotemporal Dementia*/pathology, Humans ; DNA Repeat Expansion ; Animals ; RNA-Binding Proteins/genetics

Co-morbid seizures in frontotemporal dementia: What do they tell us?

Autoren: Hashmi SA Quigg M D'Abreu A et al.

Quelle: Epilepsy research [Epilepsy Res] 2025 Dec; Vol. 218, pp. 107640. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8703089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6844 (Electronic) Linking ISSN: 09201211 NLM ISO Abbreviation: Epilepsy Res Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/epidemiology , Frontotemporal Dementia*/complications , Seizures*/epidemiology , Seizures*/drug therapy, Humans ; Female ; Male ; Middle Aged ; Aged ; Comorbidity ; Risk Factors ; Retrospective Studies ; Anticonvulsants/therapeutic use

Profiles of Vulnerability to Financial Exploitation in the Degenerative Dementias.

Autoren: Cherubini V Prata O Fattobene L et al.

Quelle: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry [Am J Geriatr Psychiatry] 2025 Dec; Vol. 33 (12), pp. 1290-1300. Date of Electronic Publication: 2025 Jun 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9309609 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-7214 (Electronic) Linking ISSN: 10647481 NLM ISO Abbreviation: Am J Geriatr Psychiatry Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/psychology , Frontotemporal Dementia*/physiopathology , Alzheimer Disease*/psychology , Alzheimer Disease*/economics , Lewy Body Disease*/psychology , Lewy Body Disease*/physiopathology , Aphasia, Primary Progressive*/psychology , Aphasia, Primary Progressive*/physiopathology , Financial Management* , Dementia*/psychology, Humans ; Aged ; Female ; Male ; Cross-Sectional Studies ; Middle Aged ; Aged, 80 and over ; Trust/psychology ; Surveys and Questionnaires

Offspring burden in Frontotemporal Dementia: the other side of caregiving.

Autoren: Cantoni V Alberici A Geviti A et al.

Quelle: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2025 Dec; Vol. 46 (12), pp. 6543-6548. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3478 (Electronic) Linking ISSN: 15901874 NLM ISO Abbreviation: Neurol Sci Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/psychology , Frontotemporal Dementia*/nursing , Caregivers*/psychology , Cost of Illness* , Adult Children*/psychology, Humans ; Female ; Male ; Middle Aged ; Aged ; Sex Factors ; Adult ; Age Factors

Semantic and phonemic advantages in Alzheimer's disease and behavioral variant-frontotemporal dementia: Insights from the Fluency Type Index.

Autoren: Aiello EN Gendarini C Cocuzza A et al.

Quelle: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Dec; Vol. 108 (3), pp. 1268-1275. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/psychology , Alzheimer Disease*/complications , Frontotemporal Dementia*/psychology , Frontotemporal Dementia*/complications , Frontotemporal Dementia*/diagnosis , Semantics* , Phonetics* , Verbal Behavior*/physiology, Humans ; Male ; Female ; Aged ; Middle Aged ; Neuropsychological Tests ; Mental Status and Dementia Tests

Computed tomography-based nnU-Net for region-specific brain structural changes across the alzheimer's continuum and frontotemporal dementia subtypes.

Autoren: Park S Kim K Lim KY et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42597. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/diagnostic imaging , Frontotemporal Dementia*/pathology , Frontotemporal Dementia*/cerebrospinal fluid , Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/pathology , Alzheimer Disease*/cerebrospinal fluid , Tomography, X-Ray Computed*/methods , Brain*/diagnostic imaging , Brain*/pathology, Humans ; Male ; Female ; Aged ; Middle Aged ; Magnetic Resonance Imaging ; Deep Learning ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/pathology ; Aged, 80 and over

Spectral brain connectivity in dementia: coherence, imaginary coherence and partial coherence analysis of EEG signals.

Autoren: Vlachos I; 1st Department of Clinical Neurology, AHEPA University Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.; Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece.; Department of Complex Systems, Institute of Computer Science of the Czech Academy of Sciences, Prague 18200, Czech Republic.

Quelle: Journal of neural engineering [J Neural Eng] 2025 Nov 27; Vol. 22 (6). Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101217933 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-2552 (Electronic) Linking ISSN: 17412552 NLM ISO Abbreviation: J Neural Eng Subsets: MEDLINE

MeSH-Schlagworte: Electroencephalography*/methods , Alzheimer Disease*/physiopathology , Alzheimer Disease*/diagnosis , Brain*/physiopathology , Nerve Net*/physiopathology , Frontotemporal Dementia*/physiopathology , Frontotemporal Dementia*/diagnosis , Dementia*/physiopathology , Dementia*/diagnosis, Humans ; Male ; Female ; Aged ; Middle Aged ; Aged, 80 and over

Glial and neuronal cell-free DNA in plasma of sporadic bvFTD and late onset primary psychiatric disease patients.

Autoren: Chatterton Z de Boer SCM Riedl L et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 06; Vol. 15 (1), pp. 38844. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/blood , Frontotemporal Dementia*/diagnosis , Frontotemporal Dementia*/genetics , Cell-Free Nucleic Acids*/blood , Neurons*/metabolism , Neuroglia*/metabolism , Mental Disorders*/blood , Mental Disorders*/diagnosis , Mental Disorders*/genetics, Humans ; Female ; Male ; Middle Aged ; Aged ; Biomarkers/blood ; Neurofilament Proteins/blood ; Glial Fibrillary Acidic Protein/blood

Design considerations for C9orf72 disease prevention trials.

Autoren: Benatar M Staffaroni AM Wuu J et al.

Quelle: Brain : a journal of neurology [Brain] 2025 Nov 04; Vol. 148 (11), pp. 3844-3855.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

MeSH-Schlagworte: C9orf72 Protein*/genetics , Amyotrophic Lateral Sclerosis*/genetics , Amyotrophic Lateral Sclerosis*/prevention & control , Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/prevention & control , Clinical Trials as Topic*/methods, Humans ; DNA Repeat Expansion/genetics ; Research Design

Neurodegenerative disease in C9orf72 repeat expansion carriers: population risk and effect of UNC13A.

Autoren: Gao J Douglas AGL Chalitsios CV et al.

Quelle: Brain : a journal of neurology [Brain] 2025 Nov 04; Vol. 148 (11), pp. 3865-3871.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

MeSH-Schlagworte: DNA Repeat Expansion*/genetics , Amyotrophic Lateral Sclerosis*/genetics , Amyotrophic Lateral Sclerosis*/epidemiology , Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/epidemiology , Neurodegenerative Diseases*/genetics , Neurodegenerative Diseases*/epidemiology , Nerve Tissue Proteins*/genetics , Proteins*/genetics, Humans ; C9orf72 Protein/genetics ; Middle Aged ; Female ; Male ; Aged ; Heterozygote ; Incidence ; Aged, 80 and over ; Genotype ; Genetic Predisposition to Disease ; Cohort Studies

Reference-Group Adjusted Behavioural Dysfunction Questionnaire Score Discriminates Highly Behavioural-Variant Frontotemporal Dementia From Major Depressive Disorder and Alzheimer's Disease Dementia.

Autoren: Semenkova A Piguet O Johnen A et al.

Quelle: European journal of neurology [Eur J Neurol] 2025 Nov; Vol. 32 (11), pp. e70424.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/diagnosis , Frontotemporal Dementia*/psychology , Depressive Disorder, Major*/diagnosis , Depressive Disorder, Major*/psychology , Alzheimer Disease*/diagnosis , Alzheimer Disease*/psychology, Humans ; Male ; Female ; Aged ; Cross-Sectional Studies ; Middle Aged ; Retrospective Studies ; Surveys and Questionnaires ; Diagnosis, Differential ; Prospective Studies

Susceptibility to visual hallucinations in the amyotrophic lateral sclerosis-frontotemporal dementia spectrum: The role of dysfunctional attentional networks.

Autoren: Tse NY Orlando IF O'Callaghan C et al.

Quelle: Cortex; a journal devoted to the study of the nervous system and behavior [Cortex] 2025 Nov; Vol. 192, pp. 213-226. Date of Electronic Publication: 2025 Sep 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Masson Country of Publication: Italy NLM ID: 0100725 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1973-8102 (Electronic) Linking ISSN: 00109452 NLM ISO Abbreviation: Cortex Subsets: MEDLINE

MeSH-Schlagworte: Amyotrophic Lateral Sclerosis*/physiopathology , Amyotrophic Lateral Sclerosis*/psychology , Amyotrophic Lateral Sclerosis*/complications , Amyotrophic Lateral Sclerosis*/diagnostic imaging , Frontotemporal Dementia*/physiopathology , Frontotemporal Dementia*/psychology , Frontotemporal Dementia*/complications , Frontotemporal Dementia*/diagnostic imaging , Hallucinations*/physiopathology , Hallucinations*/psychology , Attention*/physiology, Humans ; Male ; Female ; Middle Aged ; Magnetic Resonance Imaging/methods ; Aged ; Neuropsychological Tests ; Connectome ; Executive Function/physiology ; Brain/physiopathology ; Brain/diagnostic imaging ; Nerve Net/physiopathology

Comparison of neuron-derived extracellular vesicles miRNA profile between patients with behavioural variant frontotemporal dementia and primary psychiatric disorders.

Autoren: Giudici G Fenoglio C Serpente M et al.

Quelle: Neurobiology of disease [Neurobiol Dis] 2025 Nov; Vol. 216, pp. 107132. Date of Electronic Publication: 2025 Oct 02.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

MeSH-Schlagworte: Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/metabolism , Frontotemporal Dementia*/diagnosis , Extracellular Vesicles*/metabolism , MicroRNAs*/metabolism , MicroRNAs*/genetics , Neurons*/metabolism , Mental Disorders*/metabolism , Mental Disorders*/genetics , Mental Disorders*/diagnosis , Bipolar Disorder*/diagnosis , Bipolar Disorder*/metabolism , Bipolar Disorder*/genetics, Humans ; Male ; Female ; Middle Aged ; Aged ; Retrospective Studies ; Biomarkers/metabolism

A computational ontology framework for the synthesis of multi-level pathology reports from brain MRI scans.

Autoren: Singh D Grazia A Reiz A et al.

Körperschaften: Singh D Grazia A Reiz A et al.

Quelle: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Nov; Vol. 108 (1_suppl), pp. S258-S273. Date of Electronic Publication: 2025 Apr 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE

MeSH-Schlagworte: Magnetic Resonance Imaging*/methods , Alzheimer Disease*/pathology , Alzheimer Disease*/diagnostic imaging , Brain*/pathology , Brain*/diagnostic imaging , Frontotemporal Dementia*/pathology , Frontotemporal Dementia*/diagnostic imaging, Humans ; Male ; Female ; Aged ; Atrophy/pathology ; Neural Networks, Computer ; Middle Aged

"The DESCRIBE-ALS-FTD study: a prospective multicenter observational study of the ALS-FTD spectrum".

Autoren: Hermann A Prudlo J Kasper E et al.

Körperschaften: Hermann A Prudlo J Kasper E et al.

Quelle: Amyotrophic lateral sclerosis & frontotemporal degeneration [Amyotroph Lateral Scler Frontotemporal Degener] 2025 Nov; Vol. 26 (7-8), pp. 720-728. Date of Electronic Publication: 2025 Jun 09.

Publikationsart: Journal Article; Multicenter Study; Observational Study

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101587185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2167-9223 (Electronic) Linking ISSN: 21678421 NLM ISO Abbreviation: Amyotroph Lateral Scler Frontotemporal Degener Subsets: MEDLINE

MeSH-Schlagworte: Amyotrophic Lateral Sclerosis*/genetics , Amyotrophic Lateral Sclerosis*/diagnosis , Amyotrophic Lateral Sclerosis*/physiopathology , Frontotemporal Dementia*/diagnosis , Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/physiopathology, Aged ; Female ; Humans ; Male ; Middle Aged ; Cross-Sectional Studies ; Disease Progression ; Prospective Studies

EEG Microstate Differences Between Alzheimer's Disease, Frontotemporal Dementia, and Healthy Controls Using 4 and 7 Clustering Classes with a Ratio Approach.

Autoren: Chang J; Department of Psychology, Williams College, 39 Chapin Hall Drive, Williamstown, MA 01267, USA.; Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

Quelle: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2025 Oct 25; Vol. 61 (11). Date of Electronic Publication: 2025 Oct 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/physiopathology , Alzheimer Disease*/diagnosis , Alzheimer Disease*/classification , Frontotemporal Dementia*/physiopathology , Frontotemporal Dementia*/diagnosis , Frontotemporal Dementia*/classification , Electroencephalography*/methods, Humans ; Male ; Female ; Aged ; Middle Aged ; Cluster Analysis ; Case-Control Studies ; Mental Status and Dementia Tests ; Diagnosis, Differential

Assessing the causal association between celiac disease and Alzheimer disease and frontotemporal dementia: A bidirectional Mendelian randomization approach.

Autoren: Liu Y Zhang H

Quelle: Medicine [Medicine (Baltimore)] 2025 Oct 17; Vol. 104 (42), pp. e45059.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/genetics , Alzheimer Disease*/epidemiology , Frontotemporal Dementia*/genetics , Frontotemporal Dementia*/epidemiology , Celiac Disease*/genetics , Celiac Disease*/epidemiology , Celiac Disease*/complications, Humans ; Mendelian Randomization Analysis ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease