Výsledky vyhľadávania - "Fibroblasts/drug effects"

Silk Sericin/Chitosan Supramolecular Multilayered Thin Films as Sustainable Cytocompatible Nanobiomaterials

Autori: Miguel Rosas Cristiana F. V. Sousa Ana Pereira a ďalší

Zdroj: Biomacromolecules. 26:296-310

Predmety: Chitosan, Sericins/chemistry, Layer-by-Layer technology, Cultured, Cells, Self-assembled nanobiomaterials, Bombyx/chemistry, Silk sericin, Cytocompatibility, Fibroblasts/drug effects, Silk/chemistry, Fourier Transform Infrared, Humans, Animals, Tissue Engineering/methods, Chitosan/chemistry, Nanofibrillar matrices, Spectroscopy, Biocompatible Materials/chemistry

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39680042
https://ciencia.ucp.pt/en/publications/672ff990-6dec-4433-b38b-c7ea412ae1d0
https://doi.org/10.1021/acs.biomac.4c01146
http://hdl.handle.net/10773/43096

Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium

Autori: Dagmar Faust Christine Wenz Stefanie Holm a ďalší

Prispievatelia: Dagmar Faust Christine Wenz Stefanie Holm a ďalší

Zdroj: Arch Toxicol

Predmety: Membrane Potential, Mitochondrial, 0301 basic medicine, 0303 health sciences, 610 Medizin, Cell Communication, Fibroblasts, Mice, Oxidative Stress, 03 medical and health sciences, tert-Butylhydroperoxide, Molecular Toxicology, 610 Medical sciences, Cell Line, Tumor, Ferroptosis, Humans, Animals, Calcium, DNA Breaks, Double-Stranded, Lipid Peroxidation, Cell–cell contacts, Calcium/metabolism [MeSH], Cell Line, Tumor [MeSH], Membrane Potential, Mitochondrial/drug effects [MeSH], Fibroblasts/drug effects [MeSH], Humans [MeSH], DNA Breaks, Double-Stranded/drug effects [MeSH], Animals [MeSH], Ferroptosis/drug effects [MeSH], Lipid Peroxidation/drug effects [MeSH], Mice [MeSH], Cell Communication/drug effects [MeSH], tert-Butylhydroperoxide/toxicity [MeSH], Oxidative Stress/drug effects [MeSH], Toxicity, Fibroblasts/metabolism [MeSH]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38814333
https://repository.publisso.de/resource/frl:6507370

Ischemia does not provoke the full immune training repertoire in human cardiac fibroblasts

Autori: Constantin Mann Carolin van Alst Simone Gorressen a ďalší

Zdroj: Naunyn-Schmiedeberg's Archives of Pharmacology
Naunyn Schmiedebergs Arch Pharmacol

Predmety: Male, 0301 basic medicine, 0303 health sciences, L-Lactate Dehydrogenase, Research, Myocardium, TOR Serine-Threonine Kinases, Medizin, Myocardial Reperfusion Injury, Fibroblasts, Hypoxia-Inducible Factor 1, alpha Subunit, Mice, Inbred C57BL, 03 medical and health sciences, Humans, Animals, Cytokines, L-Lactate Dehydrogenase/metabolism [MeSH], Mice, Inbred C57BL [MeSH], Glycolysis, Myocardial Reperfusion Injury/metabolism [MeSH], Fibroblasts/drug effects [MeSH], Humans [MeSH], Cytokines/metabolism [MeSH], Animals [MeSH], Inflammasome, Ischemia, Male [MeSH], Cardiac fibroblasts, Hypoxia-Inducible Factor 1, alpha Subunit/metabolism [MeSH], Cells, Cultured [MeSH], Myocardial Reperfusion Injury/immunology [MeSH], TOR Serine-Threonine Kinases/metabolism [MeSH], Myocardium/immunology [MeSH], Myocardial, Fibroblasts/metabolism [MeSH], Trained immunity, Myocardium/metabolism [MeSH], Cells, Cultured

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38652279
https://repository.publisso.de/resource/frl:6493326

A spheroid whole mount drug testing pipeline with machine-learning based image analysis identifies cell-type specific differences in drug efficacy on a single-cell level

Autori: Vitacolonna, Mario Bruch, Roman Schneider, Richard a ďalší

Zdroj: BMC Cancer
BMC Cancer, Vol 24, Iss 1, Pp 1-23 (2024)
BMC Cancer, 24 (1), Art.-Nr.: 1542

Predmety: ddc:004, 0301 basic medicine, Antineoplastic Agents, Apoptosis, Machine Learning, 03 medical and health sciences, Imaging, Three-Dimensional, 3D drug testing, Spheroids, Cellular, Cell Line, Tumor, Image Processing, Computer-Assisted, Humans, Cell Line, Tumor [MeSH], Microscopy, Confocal/methods [MeSH], Fibroblasts/drug effects [MeSH], Humans [MeSH], Apoptosis/drug effects [MeSH], Antineoplastic Agents/pharmacology [MeSH], Tumor microenvironment, Drug resistance, Spheroids, Cellular/drug effects [MeSH], 3D co-culture, Image Processing, Computer-Assisted/methods [MeSH], Drug Screening Assays, Antitumor/methods [MeSH], Single-cell analysis, Doxorubicin/pharmacology [MeSH], Single-Cell Analysis/methods [MeSH], Research, Machine Learning [MeSH], Coculture Techniques [MeSH], Imaging, Three-Dimensional/methods [MeSH], Deep-learning image analysis, Cell Proliferation/drug effects [MeSH], Fibroblasts/metabolism [MeSH], RC254-282, Cell Proliferation, 0303 health sciences, Microscopy, Confocal, DATA processing & computer science, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Fibroblasts, Coculture Techniques, Doxorubicin, Single-Cell Analysis, Drug Screening Assays, Antitumor

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39696122
https://doaj.org/article/94688b951250495fb6faafe8830e39c4
https://repository.publisso.de/resource/frl:6497322

Targeting TGF beta receptor 1 in head and neck squamous cell carcinoma

Autori: Jank, Bernhard J Schnoell, Julia Kladnik, Katharina a ďalší

Zdroj: Oral Diseases. 30:1114-1127

Predmety: Male, Radiation-Sensitizing Agents, Receptor, Transforming Growth Factor-beta Type I, Antineoplastic Agents, Radiation-Sensitizing Agents Therapeutic Use, Receptor, Transforming Growth Factor-beta Type I Antagonists & Inhibitors, Cancer-Associated Fibroblasts, Cell Line, Tumor, Tumor Microenvironment, Receptor, Transforming Growth Factor-beta Type I Metabolism, Humans, RNA, Messenger, RNA, Messenger Metabolism, Cancer-Associated Fibroblasts Metabolism, Antineoplastic Agents Therapeutic Use, Aged, Head and Neck Neoplasms Genetics, Aniline Compounds, Head and Neck Neoplasms Metabolism, Squamous Cell Carcinoma of Head and Neck, Middle Aged, Triazoles, Antineoplastic Agents Pharmacology, Radiation-Sensitizing Agents Pharmacology, Cancer-Associated Fibroblasts Drug Effects, Squamous Cell Carcinoma of Head and Neck Metabolism, Head and Neck Neoplasms, Squamous Cell Carcinoma of Head and Neck Pathology, Female, Squamous Cell Carcinoma of Head and Neck Genetics

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37154295
https://phaidra.vetmeduni.ac.at/o:4246
https://doi.org/10.1111/odi.14594

It takes two peroxisome proliferator-activated receptors (PPAR-β/δ and PPAR-γ) to tango idiopathic pulmonary fibrosis

Autori: Boateng, Eistine Bonilla-Martinez, Rocio Ahlemeyer, Barbara a ďalší

Zdroj: Respir Res
Respiratory Research, Vol 25, Iss 1, Pp 1-19 (2024)

Predmety: Male, new insights, Fibroblasts/metabolism [MeSH], Peroxisome Proliferator-Activated Receptors/metabolism [MeSH], Female [MeSH], Catalase, Fibroblasts/drug effects [MeSH], PEX13, Humans [MeSH], Peroxisomes/drug effects [MeSH], TGF-β1, PPAR-beta/metabolism [MeSH], Peroxisome, Idiopathic Pulmonary Fibrosis/pathology [MeSH], Matrix metalloproteinases, PPAR-beta/agonists [MeSH], Research, Transforming Growth Factor beta1/metabolism [MeSH], Human lung fibroblasts, Cells, Cultured [MeSH], PPAR delta/metabolism [MeSH], PPAR-beta/genetics [MeSH] [PPAR gamma/metabolism [MeSH], Fibroblasts/pathology [MeSH], Idiopathic pulmonary fibrosis, Collagen, Idiopathic Pulmonary Fibrosis/metabolism [MeSH], PPAR gamma/genetics [MeSH], Idiopathic Pulmonary Fibrosis/genetics [MeSH], Male [MeSH], PPAR, Peroxisomes/metabolism [MeSH], PPAR delta/genetics [MeSH], Pulmonary fibrosis], RC705-779, Peroxisome Proliferator-Activated Receptors, Fibroblasts, Idiopathic Pulmonary Fibrosis, PPAR gamma, Transforming Growth Factor beta1, Diseases of the respiratory system, Peroxisomes, Humans, Female, PPAR delta, PPAR-beta, Cells, Cultured

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39313791
https://doaj.org/article/497c1b77bedd4f42ab38ca4d615984cc
https://repository.publisso.de/resource/frl:6494852

Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response

Autori: Rath, Sandip K. Nyamsuren, Gunsmaa Tampe, Björn a ďalší

Prispievatelia: Rath, Sandip K. Nyamsuren, Gunsmaa Tampe, Björn a ďalší

Zdroj: Clin Epigenetics
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-20 (2024)

Predmety: Male, 0301 basic medicine, DNA Repair, QH426-470, Dioxygenases, Non-homologous end joining, Homologous recombination, Dioxygenases/genetics [MeSH], DNA-Binding Proteins/genetics [MeSH], DNA-Binding Proteins/metabolism [MeSH], DNA Damage/drug effects [MeSH], Male [MeSH], Cell Proliferation/genetics [MeSH], DNA Repair/drug effects [MeSH], TET3, Dioxygenases/metabolism [MeSH], Fibroblasts/metabolism [MeSH], Myocardium/metabolism [MeSH], TGF-ß, Clinical Epigenetics of Heart Failure, Fibroblasts/drug effects [MeSH], Humans [MeSH], Animals [MeSH], Fibrosis, Fibrosis/genetics [MeSH], Myocardium/pathology [MeSH], Mice [MeSH], Proto-Oncogene Proteins/metabolism [MeSH], Research, Proto-Oncogene Proteins/genetics [MeSH], Cell Proliferation/drug effects [MeSH], Mice, 03 medical and health sciences, Proto-Oncogene Proteins, Genetics, Animals, Humans, Cell Proliferation, 0303 health sciences, Myocardium, Fibroblasts, 3. Good health, DNA-Binding Proteins, Medicine, DNA Damage

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39192299
https://doaj.org/article/c9732583a636444882ccab2ad924f6f6
https://resolver.sub.uni-goettingen.de/purl?gro-2/144673
https://repository.publisso.de/resource/frl:6501404

Cytotoxicity of dental ceramic materials on human gingival fibroblasts

Autori: Omid Savabi Farahnaz Nejatidanesh Morteza Sharifi a ďalší

Zdroj: Dental Research Journal, Vol 21, Iss 1, Pp 53-53 (2024)

Predmety: Dentistry, fibroblasts/drug effects, RK1-715, ceramics, dental materials/toxicity, gingiva/drug effects

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39512582
https://doaj.org/article/9b8c4c0dca924018999f53729e484be6

Lung fibroblast-derived extracellular vesicles and soluble factors alleviate elastase-induced lung injury

Autori: van der Koog, Luke Boerrigter, Myrthe Gorter, Iris a ďalší

Zdroj: van der Koog, L, Boerrigter, M, Gorter, I, Gosens, R & Nagelkerke, A 2024, 'Lung fibroblast-derived extracellular vesicles and soluble factors alleviate elastase-induced lung injury', American Journal of Respiratory Cell and Molecular Biology, vol. 974, 176612. https://doi.org/10.1016/j.ejphar.2024.176612

Predmety: Extracellular Vesicles/metabolism, Animals, Fibroblasts/drug effects, Pancreatic Elastase, Lung/pathology, Mice, Humans, Lung Injury/pathology, Cell Line, Male, Inbred C57BL, Disease Models, Animal, Solubility

Popis súboru: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38677537; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/2b070523-35e5-4e74-b515-09639b7879dd; info:eu-repo/semantics/altIdentifier/pissn/1044-1549; info:eu-repo/semantics/altIdentifier/eissn/1535-4989

Dostupnosť: https://hdl.handle.net/11370/2b070523-35e5-4e74-b515-09639b7879dd
https://research.rug.nl/en/publications/2b070523-35e5-4e74-b515-09639b7879dd
https://doi.org/10.1016/j.ejphar.2024.176612
https://pure.rug.nl/ws/files/984152934/1-s2.0-S0014299924003005-main.pdf
https://www.scopus.com/pages/publications/85191286908

Biological activity of rat fibroblast interferon beta

Zdroj: Radiology and oncology, pp. vol27(1993):4 ; 307-311, 1993. ; ISSN: 1318-2099 ; Ljubljana

Predmety: fibroblasts-drug effects, interferon-beta, rats, info:eu-repo/classification/udc/616-091.8:615.281.7.015.44

Popis súboru: application/pdf

Relation: https://dirros.openscience.si/IzpisGradiva.php?id=17713; https://dirros.openscience.si/Dokument.php?id=24061&dn=; https://plus.cobiss.net/cobiss/si/sl/bib/5724676

Dostupnosť: https://dirros.openscience.si/IzpisGradiva.php?id=17713
https://dirros.openscience.si/Dokument.php?id=24061&dn=
https://plus.cobiss.net/cobiss/si/sl/bib/5724676
https://hdl.handle.net/20.500.12556/DiRROS-17713

Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice

Autori: Manja Newe Theresa A. Kant Maximilian Hoffmann a ďalší

Zdroj: Naunyn Schmiedebergs Arch Pharmacol

Predmety: Male, Mice, Knockout, 0301 basic medicine, 0303 health sciences, Anti-Inflammatory Agents, Non-Steroidal, Cell Differentiation, Fibroblasts, Protein Serine-Threonine Kinases, Fibrosis, 3. Good health, Disease Models, Animal, Mice, 03 medical and health sciences, Fibroblasts/pathology [MeSH], Cell Differentiation/drug effects [MeSH], Skin/drug effects [MeSH], Collagen, Skin/pathology [MeSH], Original Article, Collagen/metabolism [MeSH], Male [MeSH], Phenoconversion, Creatinine/blood [MeSH], Disease Models, Animal [MeSH], Skin, Female [MeSH], Fibroblasts/drug effects [MeSH], Protein Serine-Threonine Kinases/genetics [MeSH], Anti-Inflammatory Agents, Non-Steroidal/administration, Anti-Inflammatory Agents, Non-Steroidal/pharmacology [MeSH], Osteopontin/genetics [MeSH], Animals [MeSH], Cytoskeleton, Mice, Knockout [MeSH], Mesalamine/toxicity [MeSH], Myofibroblasts, Mice [MeSH], Fibrosis/prevention, Mesalamine/administration, Mesalamine/pharmacology [MeSH], Anti-Inflammatory Agents, Non-Steroidal/toxicity [MeSH], Creatinine, Animals, Female, Osteopontin, Mesalamine

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00210-021-02135-w.pdf
https://pubmed.ncbi.nlm.nih.gov/34410453
https://link.springer.com/content/pdf/10.1007/s00210-021-02135-w.pdf
https://link.springer.com/article/10.1007/s00210-021-02135-w
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514377
https://repository.publisso.de/resource/frl:6447999

Cancer‐associated fibroblasts induce an aggressive phenotypic shift in non‐malignant breast epithelial cells via interleukin‐8 and S100A8

Autori: Nam Hoon Cho Minsoo Koh Seung Yeon Lee a ďalší

Prispievatelia: Nam Hoon Cho Minsoo Koh Seung Yeon Lee a ďalší

Zdroj: Journal of Cellular Physiology. 236:7014-7032

Predmety: 0301 basic medicine, Breast Neoplasms / drug therapy, Nude, Calgranulin A / genetics, Paracrine Communication, Mice, Cancer-Associated Fibroblasts, Cell Movement, CCAAT-Enhancer-Binding Protein-beta / genetics, S100A8, Inbred BALB C, Mice, Inbred BALB C, Sulfonamides, 0303 health sciences, Tumor, Cultured, Transcription Factor RelA / genetics, invasion, Tumor Cells, 3. Good health, Cancer-Associated Fibroblasts / metabolism, Phenotype, Interleukin-8 / genetics, Cancer-Associated Fibroblasts / pathology, Breast Neoplasms / pathology, Female, Interleukin-8 / metabolism, cancer-associated fibroblasts, Cancer-Associated Fibroblasts / drug effects, Signal Transduction, Epithelial-Mesenchymal Transition, Mice, Nude, Breast Neoplasms, Epithelial Cells / pathology, Cell Line, 03 medical and health sciences, breast cancer, Cell Line, Tumor, Animals, Humans, Transcription Factor RelA / metabolism, Calgranulin A, Neoplasm Invasiveness, Sulfonamides / pharmacology, CCAAT-Enhancer-Binding Protein-beta, Interleukin-8, Epithelial Cells / metabolism, interleukin-8, Breast Neoplasms / metabolism, Calgranulin A / metabolism, Epithelial Cells, Xenograft Model Antitumor Assays, Coculture Techniques, Breast Neoplasms / genetics, CCAAT-Enhancer-Binding Protein-beta / metabolism

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33748944
https://www.ncbi.nlm.nih.gov/pubmed/33748944
https://europepmc.org/article/MED/33748944
https://snucm.elsevierpure.com/en/publications/cancer-associated-fibroblasts-induce-an-aggressive-phenotypic-shi
https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.30364
https://pubmed.ncbi.nlm.nih.gov/33748944/

Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis

Autori: Chih Min Tang Jorge I. de la Torre Adam M. Burgoyne a ďalší

Prispievatelia: Chih Min Tang Jorge I. de la Torre Adam M. Burgoyne a ďalší

Zdroj: Oncogene
Oncogene, vol 40, iss 11

Predmety: Tumor Microenvironment / drug effects, 0301 basic medicine, Gastrointestinal Stromal Tumors / pathology, Receptor, Platelet-Derived Growth Factor alpha, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Cancer-Associated Fibroblasts, Epithelial-Mesenchymal Transition / genetics, Tumor Microenvironment, 2.1 Biological and endogenous factors, Neoplasm Metastasis, Signal Transduction / drug effects, Cancer, Platelet-Derived Growth Factor, Lymphokines, Tumor, TOR Serine-Threonine Kinases, Platelet-Derived Growth Factor / genetics, Biological Sciences, TOR Serine-Threonine Kinases / antagonists & inhibitors, 3. Good health, Cancer-Associated Fibroblasts / pathology, Paracrine Communication / drug effects, Cancer-Associated Fibroblasts / drug effects, Receptor, Signal Transduction, Epithelial-Mesenchymal Transition, Gastrointestinal Stromal Tumors, Oncology and Carcinogenesis, Clinical Sciences, Gastrointestinal Stromal Tumors / genetics, Article, Cell Line, 03 medical and health sciences, Cell Line, Tumor, Paracrine Communication, Humans, Oncology & Carcinogenesis, Protein Kinase Inhibitors, Phosphatidylinositol 3-Kinases / drug effects, Platelet-Derived Growth Factor alpha / genetics, Snail Family Transcription Factors / genetics, Biomedical and Clinical Sciences, Protein Kinase Inhibitors / pharmacology, Platelet-Derived Growth Factor alpha, TOR Serine-Threonine Kinases / genetics, Oncology and carcinogenesis, Gastrointestinal Stromal Tumors / drug therapy, Lymphokines / genetics, Biochemistry and cell biology, Biochemistry and Cell Biology, Snail Family Transcription Factors, Digestive Diseases

Popis súboru: application/pdf

Prístupová URL adresa: https://www.nature.com/articles/s41388-021-01685-w.pdf
https://pubmed.ncbi.nlm.nih.gov/33603171
https://europepmc.org/article/PMC/PMC7979540
https://www.nature.com/articles/s41388-021-01685-w.pdf
https://www.ncbi.nlm.nih.gov/pubmed/33603171
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979540
https://www.nature.com/articles/s41388-021-01685-w
https://www.mendeley.com/catalogue/597df1f6-5666-35ef-b090-44766dd80108/
https://escholarship.org/content/qt92q03395/qt92q03395.pdf
https://escholarship.org/uc/item/92q03395

Aucuparin Suppresses Bleomycin-Induced Pulmonary Fibrosis Via Anti-Inflammatory Activity

Autori: Mi Jeong Kim Gyeong-Eun Lee Ho-Geun Yoon a ďalší

Prispievatelia: Mi Jeong Kim Gyeong-Eun Lee Ho-Geun Yoon a ďalší

Zdroj: Journal of Medicinal Food. 24:151-160

Predmety: Fibroblasts / drug effects, Idiopathic Pulmonary Fibrosis* / drug therapy, Sesquiterpenes* / pharmacology, Macrophages / drug effects, Anti-Inflammatory Agents, 02 engineering and technology, Inbred C57BL, Idiopathic Pulmonary Fibrosis* / genetics, 01 natural sciences, Bleomycin, Mice, Animals, Lung, Anti-Inflammatory Agents / therapeutic use, bleomycin, pulmonary fibrosis, Animal, aucuparin, Macrophages, Lung / drug effects, Fibroblasts, Idiopathic Pulmonary Fibrosis, 0104 chemical sciences, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, inflammation, Disease Models, Idiopathic Pulmonary Fibrosis* / chemically induced, 0210 nano-technology, Sesquiterpenes, Anti-Inflammatory Agents / pharmacology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33512266
https://www.ncbi.nlm.nih.gov/pubmed/33512266
https://kmbase.medric.or.kr/Main.aspx?menu=01&d=KMBASE&m=VIEW&i=1161420210240020151
https://pubmed.ncbi.nlm.nih.gov/33512266/
https://www.liebertpub.com/doi/10.1089/jmf.2020.4861

Sawhorse-type diruthenium tetracarbonyl complexes containing porphyrin-derived ligands as highly selective photosensitizers for female reproductive cancer cells.

Autori: Schmitt, F. Auzias, M. Stepnicka, P. a ďalší

Predmety: Antineoplastic Agents/chemical synthesis, Antineoplastic Agents/chemistry, Carcinoma/drug therapy, Cell Line, Tumor, Cell Survival/drug effects, Cells, Cultured, Electrochemistry, Female, Fibroblasts/cytology, Fibroblasts/drug effects, Humans, Molecular Structure, Organometallic Compounds/chemical synthesis, Organometallic Compounds/chemistry, Ovarian Neoplasms/drug therapy, Photosensitizing Agents/chemical synthesis, Photosensitizing Agents/chemistry, Porphyrins/chemical synthesis, Porphyrins/chemistry, Spectrum Analysis, Uterine Cervical Neoplasms/drug therapy

Popis súboru: application/pdf

Relation: Journal of Biological Inorganic Chemistry; 1432-1327[electronic]; https://iris.unil.ch/handle/iris/95141; serval:BIB_238114A205C4; 000266924400006

Dostupnosť: https://iris.unil.ch/handle/iris/95141
https://doi.org/10.1007/s00775-009-0482-z

Human-induced pluripotent stem cell-derived cardiomyocytes from cardiac progenitor cells: effects of selective ion channel blockade.

Autori: Altomare, C. Pianezzi, E. Cervio, E. a ďalší

Predmety: Calcium Channel Blockers/pharmacology, Calcium Channels, L-Type/drug effects, L-Type/metabolism, Cell Differentiation, Cell Lineage, Cells, Cultured, Cellular Reprogramming, Delayed Rectifier Potassium Channels/antagonists & inhibitors, Delayed Rectifier Potassium Channels/metabolism, Fibroblasts/drug effects, Fibroblasts/metabolism, Humans, Induced Pluripotent Stem Cells/drug effects, Induced Pluripotent Stem Cells/metabolism, Membrane Potentials, Membrane Transport Modulators/pharmacology, Myocytes, Cardiac/drug effects, Cardiac/metabolism, Phenotype, Potassium Channel Blockers/pharmacology, Sodium Channel Blockers/pharmacology, Sodium Channels/drug effects, Sodium Channels/metabolism, Arrhythmia, Cardiac progenitor cell, Cardiomyocyte, Induced pluripotent stem cell

Relation: EP Europace; https://iris.unil.ch/handle/iris/55119; serval:BIB_5561847D27BB; 000392740000009

Dostupnosť: https://iris.unil.ch/handle/iris/55119
https://doi.org/10.1093/europace/euw352

Superficial and deep changes of cellular mechanical properties following cytoskeleton disassembly.

Autori: Kasas, S. Wang, X. Hirling, H. a ďalší

Predmety: Actins/antagonists & inhibitors, Animals, Biomechanics, COS Cells, Cercopithecus aethiops, Computer Simulation, Cytochalasin D/pharmacology, Cytoskeleton/drug effects, Cytoskeleton/physiology, Fibroblasts/cytology, Fibroblasts/drug effects, Genes, Reporter, Microscopy, Confocal, Microtubules/drug effects, Microtubules/physiology, Models, Biological, Transfection

Relation: Cell Motility and the Cytoskeleton; https://iris.unil.ch/handle/iris/37985; serval:BIB_05D22F819FAB; 000232360500005

Dostupnosť: https://iris.unil.ch/handle/iris/37985
https://doi.org/10.1002/cm.20086

Identification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assay.

Autori: Matic, I. Revandkar, A. Chen, J. a ďalší

Predmety: Animals, Cell Proliferation/drug effects, Cell Proliferation/radiation effects, Cells, Cultured, Cellular Senescence/drug effects, Cellular Senescence/radiation effects, Fibroblasts/drug effects, Gene Expression Regulation, Humans, Hydrogen Peroxide/metabolism, Interleukin-1alpha/genetics, Interleukin-1alpha/metabolism, Mice, Oxidative Stress, Plant Extracts/chemistry, Plant Extracts/pharmacology, Salvia/chemistry, PICS, Salvia haenkei, gerosuppressant, senescence, senescence-screening assay

Popis súboru: application/pdf

Relation: Aging; https://iris.unil.ch/handle/iris/229243; serval:BIB_B3FA03C03F0D; 000392527800010

Dostupnosť: https://iris.unil.ch/handle/iris/229243
https://doi.org/10.18632/aging.101076

A quantitative analysis of antagonism and inverse agonism at wild-type and constitutively active hamster alpha1B-adrenoceptors.

Autori: Hein, P. Goepel, M. Cotecchia, S. a ďalší

Predmety: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-1 Receptor Antagonists, Adrenergic alpha-Antagonists/pharmacology, Animals, Cell Line, Chromones/pharmacology, Cricetinae, Dose-Response Relationship, Drug, Doxazosin/pharmacology, Fibroblasts/cytology, Fibroblasts/drug effects, Inositol Phosphates/metabolism, Phenethylamines/pharmacology, Prazosin/analogs & derivatives, Prazosin/pharmacology, Quinazolines/pharmacology, Rats, Receptors, Adrenergic, alpha-1/genetics, Sulfonamides/pharmacology, Tetralones, Tritium/diagnostic use

Relation: Naunyn-Schmiedeberg's Archives of Pharmacology; https://iris.unil.ch/handle/iris/194400; serval:BIB_766ECE57D25B; 000166057600006

Dostupnosť: https://iris.unil.ch/handle/iris/194400
https://doi.org/10.1007/s002100000329

Unravelling the Programmed Inflammation and Tissue Repair by a Multipotential Antimicrobial K21 Silane

Autori: Daood, Umer Ilyas, Muhammad Sharjeel Bashir, Sehar a ďalší

Zdroj: Daood, U, Ilyas, M S, Bashir, S, Yousuf, N, Rashid, M, Kaur, K, Bapat, R A, Bijle, M N, Pichika, M R, Mak, K-K, Zhang, S, Sheikh, Z, Khan, A S, Peters, O & Matinlinna, J P 2025, 'Unravelling the Programmed Inflammation and Tissue Repair by a Multipotential Antimicrobial K21 Silane', International Dental Journal, vol. 75, no. 2, pp. 1277-1291. https://doi.org/10.1016/j.identj.2024.09.012

Predmety: Animals, Wound Healing/drug effects, Rabbits, Silanes/pharmacology, Fibroblasts/drug effects, Anti-Infective Agents/pharmacology, Macrophages/drug effects, Burns/drug therapy, Inflammation/drug therapy, Cell Proliferation/drug effects, Cell Movement/drug effects, Disease Models, Animal, Humans, Phagocytosis/drug effects, Gingiva/cytology

Dostupnosť: https://research.manchester.ac.uk/en/publications/8e544262-8a5c-481c-b47a-995e79242adc
https://doi.org/10.1016/j.identj.2024.09.012