Suchergebnisse - "FATTY liver"

Fatty liver-index, systemic inflammation and cardiovascular mortality. Results from the LURIC study.

Autoren: Wissel S Scharnagl H Kleber ME et al.

Quelle: Atherosclerosis [Atherosclerosis] 2025 Dec; Vol. 411, pp. 120557. Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE

MeSH-Schlagworte: Cardiovascular Diseases*/mortality , Cardiovascular Diseases*/blood , Cardiovascular Diseases*/diagnosis , Inflammation*/mortality , Inflammation*/blood , Inflammation*/diagnosis , Fatty Liver*/mortality , Fatty Liver*/blood , Fatty Liver*/diagnosis, Humans ; Female ; Middle Aged ; Male ; Aged ; Interleukin-6/blood ; Biomarkers/blood ; C-Reactive Protein/analysis ; C-Reactive Protein/metabolism ; gamma-Glutamyltransferase/blood ; Proportional Hazards Models ; Risk Factors ; Germany/epidemiology ; Inflammation Mediators/blood ; Waist Circumference ; Body Mass Index ; Risk Assessment ; Triglycerides/blood ; Prospective Studies ; Non-alcoholic Fatty Liver Disease/mortality ; Time Factors

Adipocyte death promotes hepatic infiltration of S100A8+ macrophages and steatotic liver disease progression in mice.

Autoren: Guan Y Kim Y Wang Y et al.

Quelle: The Journal of clinical investigation [J Clin Invest] 2025 Nov 03; Vol. 135 (21). Date of Electronic Publication: 2025 Nov 03 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

MeSH-Schlagworte: Macrophages*/pathology , Macrophages*/metabolism , Calgranulin A*/metabolism , Calgranulin A*/genetics , Adipocytes*/pathology , Adipocytes*/metabolism , Non-alcoholic Fatty Liver Disease*/pathology , Non-alcoholic Fatty Liver Disease*/metabolism , Non-alcoholic Fatty Liver Disease*/genetics , Liver*/pathology , Liver*/metabolism, Animals ; Mice ; Male ; Hepatocytes/metabolism ; Hepatocytes/pathology ; CD36 Antigens/genetics ; CD36 Antigens/metabolism ; Disease Progression ; Mice, Knockout ; Fatty Liver/pathology ; Fatty Liver/metabolism

Obeticholic acid does not restore Western diet-induced alterations in hepatic mitochondrial respiration.

Autoren: Melek J Staňková P Peterová E et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118542. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: Chenodeoxycholic Acid*/analogs & derivatives , Chenodeoxycholic Acid*/pharmacology , Diet, Western*/adverse effects , Mitochondria, Liver*/drug effects , Mitochondria, Liver*/metabolism , Liver*/drug effects , Liver*/metabolism , Liver*/pathology , Fatty Liver*/drug therapy , Fatty Liver*/metabolism , Fatty Liver*/pathology, Animals ; Male ; Mice, Inbred C57BL ; Mice ; Cell Respiration/drug effects ; Disease Models, Animal ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/metabolism

The prevalence and correlates of advanced fibrosis in patients with and without diabetes mellitus and metabolic dysfunction-associated steatotic liver disease: A cross-sectional study.

Autoren: Muzurović E Topić G Todorović N et al.

Quelle: Journal of diabetes and its complications [J Diabetes Complications] 2025 Oct; Vol. 39 (10), pp. 109147. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Pub. Co Country of Publication: United States NLM ID: 9204583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-460X (Electronic) Linking ISSN: 10568727 NLM ISO Abbreviation: J Diabetes Complications Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/epidemiology , Liver Cirrhosis*/epidemiology , Liver Cirrhosis*/complications , Liver Cirrhosis*/pathology , Liver Cirrhosis*/etiology , Prediabetic State*/complications , Prediabetic State*/epidemiology , Fatty Liver*/complications , Fatty Liver*/epidemiology, Humans ; Cross-Sectional Studies ; Male ; Female ; Middle Aged ; Prevalence ; Aged ; Risk Factors ; Elasticity Imaging Techniques ; Adult ; Severity of Illness Index ; Non-alcoholic Fatty Liver Disease/complications ; Non-alcoholic Fatty Liver Disease/epidemiology

Regulation of Hepatic Stellate Cell Phenotypes in Metabolic Dysfunction-Associated Steatohepatitis.

Autoren: Kisseleva T Ganguly S Murad R et al.

Quelle: Gastroenterology [Gastroenterology] 2025 Oct; Vol. 169 (5), pp. 797-812. Date of Electronic Publication: 2025 Mar 20.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

MeSH-Schlagworte: Hepatic Stellate Cells*/metabolism , Hepatic Stellate Cells*/pathology , Liver Cirrhosis*/pathology , Liver Cirrhosis*/metabolism , Liver Cirrhosis*/etiology , Fatty Liver*/pathology , Fatty Liver*/metabolism , Liver*/pathology , Liver*/metabolism, Humans ; Phenotype ; Animals ; Non-alcoholic Fatty Liver Disease/pathology ; Non-alcoholic Fatty Liver Disease/metabolism ; Signal Transduction

JMJD8 facilitates hepatic lipid deposition and metabolic dysfunction.

Autoren: You D Ren H Jung BC et al.

Quelle: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2025 Dec 01; Vol. 329 (6), pp. E839-E848. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE

MeSH-Schlagworte: Liver*/metabolism , Liver*/pathology , Lipid Metabolism*/genetics , Jumonji Domain-Containing Histone Demethylases*/genetics , Jumonji Domain-Containing Histone Demethylases*/metabolism , Non-alcoholic Fatty Liver Disease*/metabolism , Non-alcoholic Fatty Liver Disease*/genetics, Animals ; Mice ; Mice, Knockout ; Diet, High-Fat ; Insulin Resistance/genetics ; Male ; Mice, Inbred C57BL ; Triglycerides/metabolism ; Fatty Liver/metabolism

GPAM upregulation enhances hepatic fat deposition and reduces visceral adipose tissue in response to trans-fatty acids.

Autoren: Miyake T Yoshida O Furukawa S et al.

Quelle: Journal of gastroenterology [J Gastroenterol] 2025 Dec; Vol. 60 (12), pp. 1554-1571. Date of Electronic Publication: 2025 Oct 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE

MeSH-Schlagworte: Trans Fatty Acids*/adverse effects , Trans Fatty Acids*/metabolism , Trans Fatty Acids*/administration & dosage , Intra-Abdominal Fat*/metabolism , Fatty Liver*/etiology , Fatty Liver*/metabolism , Glycerol-3-Phosphate O-Acyltransferase*/metabolism , Glycerol-3-Phosphate O-Acyltransferase*/genetics, Animals ; Mice ; Diet, High-Fat/adverse effects ; Up-Regulation ; Male ; Humans ; Liver/metabolism ; Liver/pathology ; Mice, Inbred C57BL ; Disease Models, Animal ; Oleic Acid ; Palmitic Acid ; Triglycerides/metabolism ; Triglycerides/blood ; Non-alcoholic Fatty Liver Disease ; Oleic Acids

NAD + in fatty liver disease: mechanistic insights and associated targets.

Autoren: Guo Y Wang Y Wu S et al.

Quelle: Cell biology and toxicology [Cell Biol Toxicol] 2025 Nov 26; Vol. 41 (1), pp. 156. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Springer Country of Publication: Switzerland NLM ID: 8506639 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6822 (Electronic) Linking ISSN: 07422091 NLM ISO Abbreviation: Cell Biol Toxicol Subsets: MEDLINE

MeSH-Schlagworte: NAD*/metabolism , Fatty Liver*/metabolism , Fatty Liver*/pathology, Humans ; Animals ; Oxidative Stress ; Endoplasmic Reticulum Stress ; Autophagy ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/metabolism ; Non-alcoholic Fatty Liver Disease/metabolism ; Lipid Metabolism

Liu-Jun-Zi decoction alleviates metabolic dysfunction-associated steatohepatitis by modulating myogenic irisin mediated skeletal muscle-liver crosstalk.

Autoren: Wang C Liu K Ji J et al.

Quelle: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Nov 25; Vol. 148, pp. 157218. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

MeSH-Schlagworte: Fibronectins*/metabolism , Drugs, Chinese Herbal*/pharmacology , Muscle, Skeletal*/drug effects , Muscle, Skeletal*/metabolism , Liver*/drug effects , Liver*/metabolism , Fatty Liver*/drug therapy , Fatty Liver*/metabolism, Animals ; Male ; Mice ; Mice, Inbred C57BL ; Disease Models, Animal ; Non-alcoholic Fatty Liver Disease/drug therapy

Combination of THU/ALK-5i exhibits profound anti-MASH activity through suppression of lipogenesis and fibrogenesis.

Autoren: Boonloh K Lee ES Jo SH et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 14; Vol. 15 (1), pp. 39936. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Lipogenesis*/drug effects , Curcumin*/analogs & derivatives , Curcumin*/pharmacology , Liver Cirrhosis*/drug therapy , Liver Cirrhosis*/pathology , Liver Cirrhosis*/metabolism , Fatty Liver*/drug therapy , Fatty Liver*/metabolism , Fatty Liver*/pathology, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Humans ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Transforming Growth Factor beta/metabolism ; Disease Models, Animal ; Non-alcoholic Fatty Liver Disease/drug therapy ; Hepatic Stellate Cells/drug effects ; Hepatic Stellate Cells/metabolism ; Liver/pathology ; Liver/drug effects ; Cell Line

BIGH3 as a potential biomarker for fibrosis in metabolic dysfunction-associated steatotic liver disease: insights from mouse and human studies.

Autoren: Zhuang Z Zhuge F Liu Y et al.

Quelle: BMC gastroenterology [BMC Gastroenterol] 2025 Nov 13; Vol. 25 (1), pp. 805. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100968547 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-230X (Electronic) Linking ISSN: 1471230X NLM ISO Abbreviation: BMC Gastroenterol Subsets: MEDLINE

MeSH-Schlagworte: Liver Cirrhosis*/blood , Liver Cirrhosis*/etiology , Liver Cirrhosis*/diagnosis , Liver Cirrhosis*/pathology , Extracellular Matrix Proteins*/blood , Extracellular Matrix Proteins*/genetics , Fatty Liver*/complications , Fatty Liver*/blood, Animals ; Humans ; Biomarkers/blood ; Mice ; Male ; Middle Aged ; Female ; Disease Models, Animal ; Liver/pathology ; Liver/metabolism ; Mice, Inbred C57BL ; Adult ; ROC Curve ; Non-alcoholic Fatty Liver Disease ; Transforming Growth Factor beta

Assessing the effects of naltrexone-bupropion on hepatic steatosis and fibrosis in patients with T2DM and overweight or obesity: Insights from a placebo-controlled trial.

Autoren: Saidi AN Konings LAM Dietvorst CAW et al.

Quelle: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Nov; Vol. 27 (11), pp. 6624-6631. Date of Electronic Publication: 2025 Sep 02.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

MeSH-Schlagworte: Naltrexone*/therapeutic use , Obesity*/complications , Obesity*/therapy , Obesity*/drug therapy , Overweight*/complications , Overweight*/therapy , Liver Cirrhosis*/prevention & control , Liver Cirrhosis*/etiology , Liver Cirrhosis*/drug therapy , Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/drug therapy , Bupropion*/therapeutic use , Fatty Liver*/drug therapy , Fatty Liver*/prevention & control , Fatty Liver*/etiology, Humans ; Male ; Female ; Middle Aged ; Double-Blind Method ; Weight Loss/drug effects ; Adult ; Treatment Outcome ; Non-alcoholic Fatty Liver Disease ; Drug Therapy, Combination ; Anti-Obesity Agents/therapeutic use

[How far has non-invasive testing become a surrogate endpoint for the research and development of new drugs for metabolic dysfunction-associated steatohepatitis?]

Autoren: Sun YM You H

Quelle: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology [Zhonghua Gan Zang Bing Za Zhi] 2025 Oct 20; Vol. 33 (10), pp. 955-957.

Publikationsart: English Abstract; Journal Article

Info zur Zeitschrift: Publisher: Chongqing yi ke da xue, di 2 lin chuang xue yuan Bing du xing gan yan yan jiu suo Country of Publication: China NLM ID: 9710009 Publication Model: Print Cited Medium: Print ISSN: 1007-3418 (Print) Linking ISSN: 10073418 NLM ISO Abbreviation: Zhonghua Gan Zang Bing Za Zhi Subsets: MEDLINE

MeSH-Schlagworte: Fatty Liver*/drug therapy , Fatty Liver*/diagnosis, Humans ; Drug Development ; Liver/pathology ; Biomarkers ; Non-alcoholic Fatty Liver Disease ; Biopsy

Sclareol mitigates steatosis, inflammation, and fibrosis through the regulation of AMPK/SREBP1/NF-κB/TGF-β pathways in metabolic dysfunction-associated steatohepatitis.

Autoren: Yadav P Singh SK Weiskirchen R et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Oct; Vol. 191, pp. 118512. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: Sterol Regulatory Element Binding Protein 1*/metabolism , AMP-Activated Protein Kinases*/metabolism , NF-kappa B*/metabolism , Transforming Growth Factor beta*/metabolism , Inflammation*/drug therapy , Inflammation*/metabolism , Inflammation*/pathology , Liver Cirrhosis*/drug therapy , Liver Cirrhosis*/pathology , Liver Cirrhosis*/metabolism , Liver Cirrhosis*/prevention & control , Fatty Liver*/drug therapy , Fatty Liver*/pathology , Fatty Liver*/metabolism , Diterpenes*/pharmacology, Animals ; Humans ; Male ; Signal Transduction/drug effects ; Mice ; Diet, High-Fat ; Liver/drug effects ; Liver/pathology ; Liver/metabolism ; Oxidative Stress/drug effects ; Disease Models, Animal ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/drug therapy ; Cell Line, Tumor

Metabolic dysfunction-associated steatohepatitis treatment: spotlight on the latest hepatoprotective drugs.

Autoren: Kaya E Yilmaz Y Alkhouri N

Quelle: Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2025 Oct-Oct; Vol. 26 (14-15), pp. 1589-1598. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100897346 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7666 (Electronic) Linking ISSN: 14656566 NLM ISO Abbreviation: Expert Opin Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: Fatty Liver*/drug therapy , Fatty Liver*/etiology , Fatty Liver*/physiopathology , Protective Agents*/pharmacology , Protective Agents*/therapeutic use , Metabolic Diseases*/drug therapy , Metabolic Diseases*/complications, Humans ; Animals ; Obesity/complications ; Obesity/drug therapy ; Drug Development ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Molecular Targeted Therapy ; Non-alcoholic Fatty Liver Disease/drug therapy

Research progress of epidermal growth factor receptor in metabolic dysfunction-associated steatotic liver disease and related diseases.

Autoren: Wang Z Jin Z Xiong Z

Quelle: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Oct; Vol. 27 (10), pp. 5418-5431. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

MeSH-Schlagworte: ErbB Receptors*/metabolism , ErbB Receptors*/antagonists & inhibitors , Fatty Liver*/metabolism , Fatty Liver*/drug therapy , Metabolic Diseases*/metabolism, Humans ; Liver Neoplasms/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Carcinoma, Hepatocellular/metabolism ; Animals ; Liver Cirrhosis/metabolism ; Non-alcoholic Fatty Liver Disease/metabolism ; Renal Insufficiency, Chronic/metabolism ; Cardiovascular Diseases/metabolism ; Inflammation/metabolism

Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study.

Autoren: Noureddin M Harrison SA Loomba R et al.

Quelle: Lancet (London, England) [Lancet] 2025 Dec 06; Vol. 406 (10520), pp. 2644-2655. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE

MeSH-Schlagworte: Liver Cirrhosis*/drug therapy , Liver Cirrhosis*/etiology , Liver Cirrhosis*/pathology , Pyridines*/administration & dosage , Pyridines*/adverse effects , Pyridines*/therapeutic use , Fatty Liver*/drug therapy, Humans ; Double-Blind Method ; Male ; Female ; Middle Aged ; Adult ; Treatment Outcome ; Aged ; Drug Administration Schedule ; Non-alcoholic Fatty Liver Disease/drug therapy

Physical Activity by Accelerometer Inversely Associated With Liver Fibrosis; Cross-Sectional Analysis of a Longitudinal Cohort.

Autoren: Haff MG Murabito JM Vasan RS et al.

Quelle: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2025 Nov; Vol. 45 (11), pp. e70380.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

MeSH-Schlagworte: Liver Cirrhosis*/epidemiology , Liver Cirrhosis*/diagnostic imaging , Liver Cirrhosis*/prevention & control , Accelerometry* , Exercise* , Fatty Liver*, Humans ; Female ; Cross-Sectional Studies ; Male ; Middle Aged ; Longitudinal Studies ; Elasticity Imaging Techniques ; Adult ; Aged ; Logistic Models ; Body Mass Index ; Linear Models ; Multivariate Analysis ; Risk Factors ; Non-alcoholic Fatty Liver Disease

Beneficial Effects of Long-Lasting Bicarbonate-Sulfate-Calcium-Magnesium Water Intake on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Outcomes via Impacting Intestinal Permeability (IP), IP-Related Systemic Inflammation, and Oxidative Stress.

Autoren: Dallio M Romeo M Di Nardo F et al.

Quelle: Nutrients [Nutrients] 2025 Oct 31; Vol. 17 (21). Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress*/drug effects , Bicarbonates*/administration & dosage , Bicarbonates*/pharmacology , Inflammation* , Magnesium*/administration & dosage , Magnesium*/pharmacology , Fatty Liver*/metabolism, Humans ; Male ; Female ; Middle Aged ; Permeability/drug effects ; Adult ; Sulfates/administration & dosage ; Sulfates/pharmacology ; Calcium/administration & dosage ; Intestinal Mucosa/metabolism ; Treatment Outcome ; Non-alcoholic Fatty Liver Disease ; Aged ; Intestinal Barrier Function ; Haptoglobins ; Protein Precursors

The effects of coconut oil intake on metabolic disorders and fatty liver disease in mice.

Autoren: Sumi M Hasegawa Y Matsuyama T et al.

Quelle: Journal of nutritional science [J Nutr Sci] 2025 Aug 26; Vol. 14, pp. e58. Date of Electronic Publication: 2025 Aug 26 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cambridge University Press Country of Publication: England NLM ID: 101590587 Publication Model: eCollection Cited Medium: Internet ISSN: 2048-6790 (Electronic) Linking ISSN: 20486790 NLM ISO Abbreviation: J Nutr Sci Subsets: MEDLINE

MeSH-Schlagworte: Coconut Oil* , Fatty Liver*/prevention & control , Fatty Liver*/metabolism , Plant Oils*/pharmacology , Plant Oils*/therapeutic use , Metabolic Diseases*, Animals ; Mice, Inbred C57BL ; Liver/metabolism ; Liver/drug effects ; Liver/pathology ; Male ; Diet, High-Fat/adverse effects ; Mice ; Fatty Acids/analysis ; Fatty Acids/metabolism ; Lipid Metabolism/drug effects ; Weight Gain/drug effects ; Dietary Fats/administration & dosage ; Non-alcoholic Fatty Liver Disease/prevention & control ; Disease Models, Animal ; Obesity