Suchergebnisse - "Eye Pain"

Effect of selective topical anaesthesia on the initial comfort of rigid contact lenses.

Autoren: Navascues-Cornago M Maldonado-Codina C Read ML et al.

Quelle: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2025 Dec; Vol. 48 (6), pp. 102474. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9712714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5411 (Electronic) Linking ISSN: 13670484 NLM ISO Abbreviation: Cont Lens Anterior Eye Subsets: MEDLINE

MeSH-Schlagworte: Anesthetics, Local*/administration & dosage , Anesthesia, Local*/methods , Contact Lenses*/adverse effects , Propoxycaine*/administration & dosage , Eye Pain*/etiology , Eye Pain*/prevention & control , Eye Pain*/diagnosis, Humans ; Male ; Female ; Adult ; Pilot Projects ; Young Adult ; Conjunctiva/drug effects ; Cornea/drug effects ; Pain Measurement ; Middle Aged

TRPA1 inhibition reduces ocular pain and corneal neurogenic inflammation in a mouse model of dry eye disease.

Autoren: Migeon T Cordovilla A Potey A et al.

Quelle: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118625. Date of Electronic Publication: 2025 Oct 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

MeSH-Schlagworte: TRPA1 Cation Channel*/antagonists & inhibitors , TRPA1 Cation Channel*/metabolism , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/physiopathology , Cornea*/drug effects , Cornea*/innervation , Cornea*/metabolism , Neurogenic Inflammation*/drug therapy , Neurogenic Inflammation*/metabolism , Eye Pain*/drug therapy , Eye Pain*/metabolism , Acetanilides*/pharmacology , Purines*/pharmacology, Animals ; Disease Models, Animal ; Mice ; Mice, Inbred C57BL ; Male

Efficacy and Safety of Loteprednol Etabonate in Managing Pain and Inflammation After Cataract Surgery: A Systematic Review and Meta-analysis.

Autoren: Elettreby AM Alsaied MA Saleh MM et al.

Quelle: Eye & contact lens [Eye Contact Lens] 2025 Nov 01; Vol. 51 (11), pp. 481-490. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101160941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-233X (Electronic) Linking ISSN: 15422321 NLM ISO Abbreviation: Eye Contact Lens Subsets: MEDLINE

MeSH-Schlagworte: Pain, Postoperative*/drug therapy , Cataract Extraction*/adverse effects , Loteprednol Etabonate*/therapeutic use , Eye Pain*/drug therapy , Eye Pain*/etiology , Inflammation*/drug therapy , Inflammation*/etiology, Humans ; Randomized Controlled Trials as Topic ; Ophthalmic Solutions

Analgesic efficacy of 7 different topical NSAIDs in panretinal photocoagulation-associated pain.

Autoren: Sakallıoğlu AK Engi̇n T Bek T et al.

Quelle: BMC ophthalmology [BMC Ophthalmol] 2025 Oct 02; Vol. 25 (1), pp. 539. Date of Electronic Publication: 2025 Oct 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415 (Electronic) Linking ISSN: 14712415 NLM ISO Abbreviation: BMC Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Laser Coagulation*/adverse effects , Eye Pain*/drug therapy , Eye Pain*/etiology , Eye Pain*/diagnosis , Pain, Postoperative*/drug therapy , Pain, Postoperative*/diagnosis, Humans ; Female ; Male ; Middle Aged ; Aged ; Pain Measurement ; Adult ; Administration, Topical ; Diabetic Retinopathy/surgery ; Ophthalmic Solutions

Corneal intrastromal silicone injection in severe corneal decompensation as a last resort for pain management: A case series.

Autoren: Rizk M Bijon J Gatinel D et al.

Quelle: Journal francais d'ophtalmologie [J Fr Ophtalmol] 2025 Oct; Vol. 48 (8), pp. 104626. Date of Electronic Publication: 2025 Aug 27.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Masson Country of Publication: France NLM ID: 7804128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1773-0597 (Electronic) Linking ISSN: 01815512 NLM ISO Abbreviation: J Fr Ophtalmol Subsets: MEDLINE

MeSH-Schlagworte: Corneal Stroma*/surgery , Corneal Stroma*/drug effects , Corneal Stroma*/pathology , Silicones*/administration & dosage , Pain Management*/methods , Eye Pain*/therapy , Eye Pain*/etiology , Eye Pain*/drug therapy , Corneal Edema*/therapy , Corneal Diseases*/complications , Corneal Diseases*/therapy, Humans ; Female ; Male ; Middle Aged ; Injections, Intraocular

Exploration of imaging and molecular biomarkers for differentiation of neuropathic corneal pain from dry eye syndrome.

Autoren: Cheng J Liu C Yu M et al.

Quelle: The ocular surface [Ocul Surf] 2025 Oct; Vol. 38, pp. 230-241. Date of Electronic Publication: 2025 Aug 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101156063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5913 (Electronic) Linking ISSN: 15420124 NLM ISO Abbreviation: Ocul Surf Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/metabolism , Cornea*/innervation , Cornea*/metabolism , Cornea*/diagnostic imaging , Tears*/metabolism , Neuralgia*/diagnosis , Neuralgia*/metabolism , Eye Pain*/diagnosis , Eye Pain*/metabolism , Eye Proteins*/metabolism, Humans ; Female ; Cross-Sectional Studies ; Male ; Middle Aged ; Biomarkers/metabolism ; Adult ; Microscopy, Confocal/methods ; Proteomics/methods ; Diagnosis, Differential ; Aged ; Pain Measurement

Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain.

Autoren: Karakoleva EV Pondelis N Talbert C et al.

Quelle: The ocular surface [Ocul Surf] 2025 Oct; Vol. 38, pp. 64-71. Date of Electronic Publication: 2025 Jun 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101156063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5913 (Electronic) Linking ISSN: 15420124 NLM ISO Abbreviation: Ocul Surf Subsets: MEDLINE

MeSH-Schlagworte: Eye Pain*/physiopathology , Eye Pain*/diagnosis , Chronic Pain*/physiopathology , Chronic Pain*/diagnosis , Photosensitivity Disorders*/diagnosis , Photosensitivity Disorders*/physiopathology, Humans ; Female ; Male ; Middle Aged ; Prospective Studies ; Adult ; Case-Control Studies ; Surveys and Questionnaires ; Light/adverse effects ; Aged ; Pain Measurement

Differences in pre-surgical baseline tear proteome are associated with persistent post-refractive surgery pain.

Autoren: Harkness BM Chen S Reddy AP et al.

Quelle: The ocular surface [Ocul Surf] 2025 Oct; Vol. 38, pp. 219-229. Date of Electronic Publication: 2025 Aug 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101156063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5913 (Electronic) Linking ISSN: 15420124 NLM ISO Abbreviation: Ocul Surf Subsets: MEDLINE

MeSH-Schlagworte: Tears*/metabolism , Pain, Postoperative*/metabolism , Pain, Postoperative*/diagnosis , Pain, Postoperative*/etiology , Proteome*/metabolism , Eye Proteins*/metabolism , Keratomileusis, Laser In Situ*/adverse effects , Eye Pain*/metabolism , Eye Pain*/etiology , Eye Pain*/diagnosis , Photorefractive Keratectomy*/adverse effects, Humans ; Female ; Male ; Adult ; Myopia/surgery ; Myopia/metabolism ; Middle Aged ; Pain Measurement ; Young Adult ; Follow-Up Studies

Randomised Controlled Trial: Influence of Subconjunctival Anaesthesia Duration on Pain Perception During Intravitreal Injections.

Autoren: Kim J Han LS Robinson L et al.

Quelle: Clinical & experimental ophthalmology [Clin Exp Ophthalmol] 2025 Nov; Vol. 53 (8), pp. 918-924. Date of Electronic Publication: 2025 Jul 01.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Wiley-Blackwell Pub. Asia Country of Publication: Australia NLM ID: 100896531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1442-9071 (Electronic) Linking ISSN: 14426404 NLM ISO Abbreviation: Clin Exp Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Intravitreal Injections* , Anesthesia, Local*/methods , Anesthetics, Local*/administration & dosage , Lidocaine*/administration & dosage , Pain Perception*/physiology , Eye Pain*/diagnosis , Pain, Procedural*, Humans ; Female ; Male ; Pain Measurement ; Conjunctiva/drug effects ; Single-Blind Method ; Aged ; Middle Aged ; Time Factors ; Angiogenesis Inhibitors/administration & dosage ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Aged, 80 and over

Approach to Eye Pain: Differential Diagnosis and Work Up for the Neurologist.

Autoren: Robblee J Patel JN

Quelle: Current neurology and neuroscience reports [Curr Neurol Neurosci Rep] 2025 Jul 12; Vol. 25 (1), pp. 48. Date of Electronic Publication: 2025 Jul 12.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Current Science Inc Country of Publication: United States NLM ID: 100931790 Publication Model: Electronic Cited Medium: Internet ISSN: 1534-6293 (Electronic) Linking ISSN: 15284042 NLM ISO Abbreviation: Curr Neurol Neurosci Rep Subsets: MEDLINE

MeSH-Schlagworte: Eye Pain*/diagnosis , Eye Pain*/etiology , Neurologists* , Eye Diseases*/diagnosis , Eye Diseases*/complications, Humans ; Diagnosis, Differential

Analysis of the nonclinical safety and antinociceptive potential of amentoflavone (AMT) on corneal pain in adult zebrafish (Danio rerio).

Autoren: Frota LS Magalhães FEA de Sousa DB et al.

Quelle: Physiology & behavior [Physiol Behav] 2026 Jan 01; Vol. 303, pp. 115121. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0151504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-507X (Electronic) Linking ISSN: 00319384 NLM ISO Abbreviation: Physiol Behav Subsets: MEDLINE

MeSH-Schlagworte: Analgesics*/therapeutic use , Analgesics*/pharmacology , Biflavonoids*/therapeutic use , Biflavonoids*/pharmacology , Eye Pain*/drug therapy, Animals ; Zebrafish ; Disease Models, Animal ; Naloxone/pharmacology ; Male ; Pain Measurement/drug effects ; Cornea/drug effects ; Dose-Response Relationship, Drug ; TRPV Cation Channels/metabolism

Long-Term Clinical and Molecular Changes in Dry Eye Disease and Chronic Ocular Pain.

Autoren: Valencia-Sandonís C Calderón-García AÁ Blanco-Vázquez M et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 12; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/genetics , Dry Eye Syndromes*/pathology , Chronic Pain*/metabolism , Chronic Pain*/genetics , Eye Pain*/metabolism , Eye Pain*/genetics, Humans ; Female ; Male ; Middle Aged ; Tears/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Cytokines/metabolism ; Aged ; Cornea/metabolism ; Cornea/pathology ; Adult ; Substance P/metabolism ; Conjunctiva/metabolism ; Conjunctiva/pathology

P2X4 Receptor Antagonist Ameliorates Ocular Pain in Rats After Lacrimal Gland Removal.

Autoren: Chen M Bäurle S Karlstetter M et al.

Quelle: Translational vision science & technology [Transl Vis Sci Technol] 2025 Sep 02; Vol. 14 (9), pp. 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association for Research in Vision and Ophthalmology Country of Publication: United States NLM ID: 101595919 Publication Model: Print Cited Medium: Internet ISSN: 2164-2591 (Electronic) Linking ISSN: 21642591 NLM ISO Abbreviation: Transl Vis Sci Technol Subsets: MEDLINE

MeSH-Schlagworte: Purinergic P2X Receptor Antagonists*/pharmacology , Purinergic P2X Receptor Antagonists*/therapeutic use , Lacrimal Apparatus*/surgery , Eye Pain*/drug therapy , Eye Pain*/metabolism, Animals ; Male ; Rats ; Rats, Sprague-Dawley ; Cornea/innervation ; Disease Models, Animal ; Blinking/drug effects ; Microscopy, Confocal ; Ophthalmic Solutions

When ocular surface treatment fails: exploring neuropathic ocular pain in aqueous-deficient dry eye due to Sjögren's syndrome treated with mirogabalin: a case study.

Autoren: Tagawa Y Aihara Y Ishida S

Quelle: Immunological medicine [Immunol Med] 2025 Sep; Vol. 48 (3), pp. 261-265. Date of Electronic Publication: 2025 Mar 17.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Informa UK Limited Country of Publication: England NLM ID: 101736847 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2578-5826 (Electronic) Linking ISSN: 25785826 NLM ISO Abbreviation: Immunol Med Subsets: MEDLINE

MeSH-Schlagworte: Sjogren's Syndrome*/complications , Sjogren's Syndrome*/drug therapy , Sjogren's Syndrome*/diagnosis , Neuralgia*/drug therapy , Neuralgia*/etiology , Neuralgia*/diagnosis , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/diagnosis , Eye Pain*/drug therapy , Eye Pain*/etiology , Eye Pain*/diagnosis, Humans ; Female ; Middle Aged ; Ophthalmic Solutions ; Treatment Outcome

Post-Intravitreal injection pain reduction using topical NSAIDS: A comparative study.

Autoren: Shtayer C Lily Okrent Smolar A Elmalak M et al.

Quelle: European journal of ophthalmology [Eur J Ophthalmol] 2025 Sep; Vol. 35 (5), pp. 1703-1709. Date of Electronic Publication: 2023 Sep 10.

Publikationsart: Journal Article; Randomized Controlled Trial; Comparative Study

Info zur Zeitschrift: Publisher: SAGE Publishing Country of Publication: United States NLM ID: 9110772 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1724-6016 (Electronic) Linking ISSN: 11206721 NLM ISO Abbreviation: Eur J Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Diclofenac*/administration & dosage , Intravitreal Injections*/adverse effects , Eye Pain*/drug therapy , Eye Pain*/etiology , Eye Pain*/diagnosis , Phenylacetates*/administration & dosage , Benzeneacetamides*/administration & dosage, Humans ; Female ; Male ; Single-Blind Method ; Middle Aged ; Pain Measurement ; Aged ; Ophthalmic Solutions/administration & dosage ; Prospective Studies ; Administration, Topical ; Angiogenesis Inhibitors/administration & dosage ; Treatment Outcome ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Ranibizumab

The eye as a window to oral and pain symptoms in Sjögren's disease.

Autoren: Baeza DC Sanchez V Goldhardt R et al.

Quelle: The British journal of ophthalmology [Br J Ophthalmol] 2025 Aug 20; Vol. 109 (9), pp. 982-989. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 0421041 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-2079 (Electronic) Linking ISSN: 00071161 NLM ISO Abbreviation: Br J Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Sjogren's Syndrome*/complications , Sjogren's Syndrome*/diagnosis , Sjogren's Syndrome*/physiopathology , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/physiopathology , Eye Pain*/diagnosis , Eye Pain*/etiology , Pain*/etiology , Pain*/diagnosis, Humans ; Female ; Middle Aged ; Male ; Adult ; Tears/metabolism ; Aged

Microstructural alterations of the trigeminal ganglion in chronic ocular surface pain patients: A diffusion MRI study.

Autoren: Ortug A Reyes N Galor A et al.

Quelle: NeuroImage [Neuroimage] 2025 Aug 15; Vol. 317, pp. 121309. Date of Electronic Publication: 2025 Jun 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9215515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9572 (Electronic) Linking ISSN: 10538119 NLM ISO Abbreviation: Neuroimage Subsets: MEDLINE

MeSH-Schlagworte: Trigeminal Ganglion*/diagnostic imaging , Trigeminal Ganglion*/pathology , Eye Pain*/diagnostic imaging , Eye Pain*/pathology , Chronic Pain*/diagnostic imaging , Chronic Pain*/pathology, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult ; Diffusion Tensor Imaging/methods ; Diffusion Magnetic Resonance Imaging/methods

Trigeminal nerve blocks attenuate afferent input to the puff-induced blink reflex in chronic orbital pain assessed by high-speed video.

Autoren: Lee G Nellis J Pham CM et al.

Quelle: Orbit (Amsterdam, Netherlands) [Orbit] 2025 Aug; Vol. 44 (4), pp. 375-383. Date of Electronic Publication: 2024 Dec 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8301221 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5108 (Electronic) Linking ISSN: 01676830 NLM ISO Abbreviation: Orbit Subsets: MEDLINE

MeSH-Schlagworte: Blinking*/physiology , Blinking*/drug effects , Trigeminal Nerve*/drug effects , Trigeminal Nerve*/physiology , Nerve Block*/methods , Chronic Pain*/physiopathology , Chronic Pain*/drug therapy , Eye Pain*/physiopathology , Eye Pain*/drug therapy, Humans ; Male ; Female ; Prospective Studies ; Anesthetics, Local/administration & dosage ; Middle Aged ; Adult ; Lidocaine/administration & dosage ; Bupivacaine/administration & dosage ; Eyelids ; Video Recording ; Aged

Corneal Sensory Changes and Nerve Plexus Abnormalities in Chronic Neuropathic Ocular Pain and Dry Eye Postrefractive Surgery.

Autoren: Vázquez A Blanco-Vázquez M Martínez-Plaza E et al.

Quelle: American journal of ophthalmology [Am J Ophthalmol] 2025 Aug; Vol. 276, pp. 170-185. Date of Electronic Publication: 2025 Apr 17.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/physiopathology , Dry Eye Syndromes*/diagnosis , Cornea*/innervation , Cornea*/physiopathology , Keratomileusis, Laser In Situ*/adverse effects , Eye Pain*/physiopathology , Eye Pain*/etiology , Eye Pain*/diagnosis , Neuralgia*/physiopathology , Neuralgia*/etiology , Neuralgia*/diagnosis , Ophthalmic Nerve*/physiopathology , Chronic Pain*/physiopathology , Chronic Pain*/etiology , Chronic Pain*/diagnosis, Humans ; Prospective Studies ; Female ; Male ; Cross-Sectional Studies ; Adult ; Case-Control Studies ; Middle Aged ; Surveys and Questionnaires ; Pain Measurement ; Chronic Disease ; Tears

Local anaesthetic delivery through indwelling retrobulbar catheters for ocular pain control in horses.

Autoren: Moody LM Hicks SL Foote BC et al.

Quelle: Equine veterinary journal [Equine Vet J] 2025 Jul; Vol. 57 (4), pp. 1110-1117. Date of Electronic Publication: 2024 Oct 01.

Publikationsart: Journal Article; Randomized Controlled Trial, Veterinary

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 0173320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-3306 (Electronic) Linking ISSN: 04251644 NLM ISO Abbreviation: Equine Vet J Subsets: MEDLINE

MeSH-Schlagworte: Anesthetics, Local*/administration & dosage , Anesthetics, Local*/therapeutic use , Bupivacaine*/administration & dosage , Bupivacaine*/therapeutic use , Horse Diseases*/drug therapy , Eye Pain*/veterinary , Eye Pain*/drug therapy , Catheters, Indwelling*/veterinary, Animals ; Horses ; Cross-Over Studies ; Male ; Female ; Anesthesia, Local/veterinary