Search Results - "Extracellular Matrix"

From Protein Misfolding to Extracellular Matrix Disorganisation: Understanding Disease Pathology in Rare Skeletal Dysplasias.

Authors: Dennis EP Briggs MD

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 15; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Osteochondrodysplasias*/metabolism , Osteochondrodysplasias*/pathology , Osteochondrodysplasias*/genetics , Achondroplasia*/metabolism , Achondroplasia*/pathology , Achondroplasia*/genetics , Protein Folding*, Humans ; Cartilage Oligomeric Matrix Protein/genetics ; Cartilage Oligomeric Matrix Protein/metabolism ; Animals ; Matrilin Proteins/genetics ; Matrilin Proteins/metabolism ; Chondrocytes/metabolism ; Chondrocytes/pathology ; Extracellular Matrix Proteins/metabolism ; Extracellular Matrix Proteins/genetics ; Growth Plate/metabolism ; Growth Plate/pathology ; Mutation

SCR Disease Name: Pseudoachondroplasia

Unraveling the matrisome signatures of quiescent and activated muscle stem cells.

Authors: Guillon E Bacar H Gilquin L et al.

Source: Stem cell reports [Stem Cell Reports] 2025 Oct 14; Vol. 20 (10), pp. 102635. Date of Electronic Publication: 2025 Sep 11.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/genetics , Muscle, Skeletal*/cytology , Muscle, Skeletal*/metabolism , Stem Cells*/metabolism , Stem Cells*/cytology, Animals ; Mice ; Basement Membrane/metabolism ; Stem Cell Niche ; Gene Expression Profiling ; Transcriptome ; Extracellular Matrix Proteins/metabolism ; Extracellular Matrix Proteins/genetics

Chemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues.

Authors: Ling Z Niego B Li Q et al.

Source: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2025 Nov; Vol. 37 (47), pp. e05445. Date of Electronic Publication: 2025 Sep 06.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9885358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4095 (Electronic) Linking ISSN: 09359648 NLM ISO Abbreviation: Adv Mater Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/chemistry , Tissue Engineering*/methods , Neoplasms*/pathology , Neoplasms*/metabolism, Humans ; Cell Line, Tumor ; Tissue Scaffolds/chemistry ; Extracellular Matrix Proteins/metabolism ; Animals ; Glycosylation ; Proteomics

Extracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate.

Authors: Li YT; Department of Stem Cell Therapy Science, Graduate School of Medicine, The University of Osaka, Suita, Japan.

Source: ELife [Elife] 2025 Dec 04; Vol. 14. Date of Electronic Publication: 2025 Dec 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH Terms: Leukocytes*/physiology , Extracellular Matrix*/metabolism , Inflammation* , Transendothelial and Transepithelial Migration*, Humans ; Animals ; Extracellular Matrix Proteins/metabolism ; Basement Membrane

Decellularized matrix-hyaluronic acid-alginate hybrid hydrogels to enable a multi-layered full-thickness oral mucosa-on-a-chip.

Authors: Phan TV Pimpakan T Suwanchaikasem P et al.

Source: Journal of dentistry [J Dent] 2025 Dec; Vol. 163, pp. 106115. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE

MeSH Terms: Hydrogels*/chemistry , Alginates*/chemistry , Hyaluronic Acid*/chemistry , Mouth Mucosa*/cytology , Decellularized Extracellular Matrix*/chemistry , Tissue Engineering*/methods , Lab-On-A-Chip Devices*, Humans ; Animals ; Swine ; Human Umbilical Vein Endothelial Cells ; Keratinocytes/cytology ; Laminin ; Fibroblasts/cytology ; Cell Proliferation ; Tissue Scaffolds/chemistry ; Drug Combinations ; Collagen ; Proteoglycans ; Gingiva/cytology ; Extracellular Matrix/chemistry ; Cells, Cultured

Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins.

Authors: Luthold C Didion M Rácz VS et al.

Source: EMBO reports [EMBO Rep] 2025 Nov; Vol. 26 (21), pp. 5270-5299. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH Terms: Melanocytes*/metabolism , Melanocytes*/cytology , Cell Differentiation* , Mechanotransduction, Cellular* , Extracellular Matrix Proteins*/metabolism, Microphthalmia-Associated Transcription Factor/metabolism ; Microphthalmia-Associated Transcription Factor/genetics ; Animals ; Mice ; Focal Adhesion Kinase 1/metabolism ; Humans ; Fibronectins/metabolism ; Extracellular Matrix/metabolism ; MAP Kinase Signaling System ; Signal Transduction ; Cell Proliferation ; Cell Movement ; Extracellular Signal-Regulated MAP Kinases/metabolism

Extracellular matrix alterations in inflammatory skin diseases: emerging biomarkers and clinical implications.

Authors: Port H Andelic M Nyström A et al.

Source: Clinical and experimental dermatology [Clin Exp Dermatol] 2025 Oct 27; Vol. 50 (11), pp. 2118-2132.

Publication Type: Journal Article; Review

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7606847 Publication Model: Print Cited Medium: Internet ISSN: 1365-2230 (Electronic) Linking ISSN: 03076938 NLM ISO Abbreviation: Clin Exp Dermatol Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/pathology , Hidradenitis Suppurativa*/metabolism , Hidradenitis Suppurativa*/pathology , Psoriasis*/metabolism , Psoriasis*/pathology , Dermatitis, Atopic*/metabolism , Dermatitis, Atopic*/pathology , Skin Diseases*/metabolism, Humans ; Biomarkers/metabolism ; Extracellular Matrix Proteins/metabolism

Highly porous cryogel composed of bone matrix derived dECM and laponite for vascularized bone regeneration.

Authors: Wang X Shi Y Li X et al.

Source: Biomedical materials (Bristol, England) [Biomed Mater] 2025 Oct 17; Vol. 20 (6). Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101285195 Publication Model: Electronic Cited Medium: Internet ISSN: 1748-605X (Electronic) Linking ISSN: 17486041 NLM ISO Abbreviation: Biomed Mater Subsets: MEDLINE

MeSH Terms: Bone Regeneration* , Silicates*/chemistry , Cryogels*/chemistry , Bone Matrix*/chemistry , Decellularized Extracellular Matrix*/chemistry, Animals ; Rats ; Tissue Scaffolds/chemistry ; Osteogenesis ; Porosity ; Tissue Engineering/methods ; Rats, Sprague-Dawley ; Compressive Strength ; Biocompatible Materials/chemistry ; Cell Differentiation ; Humans ; Extracellular Matrix/chemistry ; Materials Testing ; Male ; Skull

Recellularization of scaffolds derived from precision-cut kidney slices.

Authors: Salti H Nelz SC Lichtwark S et al.

Source: Biomedical materials (Bristol, England) [Biomed Mater] 2025 Oct 03; Vol. 20 (6). Date of Electronic Publication: 2025 Oct 03.

Publication Type: Journal Article

Journal Info: Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101285195 Publication Model: Electronic Cited Medium: Internet ISSN: 1748-605X (Electronic) Linking ISSN: 17486041 NLM ISO Abbreviation: Biomed Mater Subsets: MEDLINE

MeSH Terms: Tissue Scaffolds*/chemistry , Tissue Engineering*/methods , Kidney*/cytology , Decellularized Extracellular Matrix*/chemistry, Humans ; Extracellular Matrix/chemistry ; Cell Proliferation ; Epithelial Cells/cytology ; Animals ; Materials Testing ; Cell Adhesion ; Kidney Tubules, Proximal/cytology

Native and decellularized porcine vena cava: Histological analysis and in vitro repopulation.

Authors: Massaro MS Pálek R Malečková A et al.

Source: Biomaterials advances [Biomater Adv] 2025 Dec; Vol. 177, pp. 214382. Date of Electronic Publication: 2025 Jun 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE

MeSH Terms: Tissue Scaffolds*/chemistry , Venae Cavae*/cytology , Venae Cavae*/chemistry , Decellularized Extracellular Matrix*/chemistry, Animals ; Swine ; Humans ; Human Umbilical Vein Endothelial Cells/cytology ; Endothelial Cells/cytology ; Tissue Engineering/methods ; Extracellular Matrix/chemistry ; Cells, Cultured ; Bioreactors

Decellularized scaffolds and heart valve treatment: present techniques, long-standing hurdles and the challenging future.

Authors: Tzavellas NP Simos YV Tsamis KI et al.

Source: Biomaterials advances [Biomater Adv] 2025 Dec; Vol. 177, pp. 214367. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE

MeSH Terms: Tissue Scaffolds*/chemistry , Heart Valve Prosthesis* , Heart Valves* , Tissue Engineering*/methods , Decellularized Extracellular Matrix*/chemistry, Humans ; Animals ; Extracellular Matrix/chemistry ; Bioprosthesis

Local photocrosslinking of native tissue matrix regulates lung epithelial cell mechanosensing and function.

Authors: Ahmed DW Tan ML Liu Y et al.

Source: Nature materials [Nat Mater] 2025 Nov; Vol. 24 (11), pp. 1812-1825. Date of Electronic Publication: 2025 Sep 05.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101155473 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4660 (Electronic) Linking ISSN: 14761122 NLM ISO Abbreviation: Nat Mater Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Lung*/cytology , Lung*/metabolism , Epithelial Cells*/metabolism , Epithelial Cells*/cytology , Mechanotransduction, Cellular* , Cross-Linking Reagents*/chemistry, Animals ; Humans ; Mice ; Extracellular Matrix Proteins/metabolism ; Cell Differentiation ; Light

Potential of Fibulin2 as a therapeutic target against cancer and as a diagnostic marker (Review).

Authors: Yang Y Wang Z Weng L et al.

Source: International journal of oncology [Int J Oncol] 2025 Nov; Vol. 67 (5). Date of Electronic Publication: 2025 Sep 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9306042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2423 (Electronic) Linking ISSN: 10196439 NLM ISO Abbreviation: Int J Oncol Subsets: MEDLINE

MeSH Terms: Neoplasms*/diagnosis , Neoplasms*/drug therapy , Neoplasms*/pathology , Neoplasms*/metabolism , Neoplasms*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/antagonists & inhibitors , Calcium-Binding Proteins*/metabolism , Calcium-Binding Proteins*/antagonists & inhibitors , Calcium-Binding Proteins*/genetics , Extracellular Matrix Proteins*/metabolism, Humans ; Tumor Microenvironment/drug effects ; Molecular Targeted Therapy/methods ; Extracellular Matrix/metabolism ; Animals

In vivo subcutaneous biocompatibility evaluation of decellularized tilapia fish skin in a rat model.

Authors: Borra S H K A D'souza V et al.

Source: Scientific reports [Sci Rep] 2025 Oct 30; Vol. 15 (1), pp. 37982. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Tilapia* , Skin*/chemistry , Skin*/metabolism , Biocompatible Materials* , Decellularized Extracellular Matrix*/chemistry, Animals ; Rats ; Rats, Wistar ; Wound Healing ; Male ; Materials Testing ; Extracellular Matrix

Distinct Intramuscular Extracellular Matrix Protein Responses to Exercise Training in COPD and Healthy Adults and Their Association with Muscle Remodeling.

Authors: Simoes DCM Kritikaki E Terzis G et al.

Source: Cells [Cells] 2025 Oct 22; Vol. 14 (21). Date of Electronic Publication: 2025 Oct 22.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Pulmonary Disease, Chronic Obstructive*/metabolism , Pulmonary Disease, Chronic Obstructive*/physiopathology , Exercise*/physiology , Extracellular Matrix Proteins*/metabolism , Muscle, Skeletal*/metabolism, Humans ; Male ; Female ; Middle Aged ; Adult ; Extracellular Matrix/metabolism ; Aged

Development of a biologically-inspired airway epithelial model using a bronchial decellularized scaffold: Applicability for pulmonary preclinical studies.

Authors: da Silva ACG de Mendonça ICF de Morais Carvalho-Filho S et al.

Source: Tissue & cell [Tissue Cell] 2025 Oct; Vol. 96, pp. 102943. Date of Electronic Publication: 2025 May 03.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH Terms: Bronchi*/cytology , Tissue Scaffolds*/chemistry , Epithelial Cells*/cytology , Epithelial Cells*/metabolism , Models, Biological* , Tissue Engineering*/methods , Decellularized Extracellular Matrix*/chemistry, Humans ; Animals ; Swine ; Extracellular Matrix/metabolism

MatriCom, a single-cell RNA-sequencing data mining tool to infer cell-extracellular matrix interactions.

Authors: Lamba R Paguntalan AM Petrov PB et al.

Source: Journal of cell science [J Cell Sci] 2025 Jul 01; Vol. 138 (13). Date of Electronic Publication: 2025 Jul 11.

Publication Type: Journal Article

Journal Info: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

MeSH Terms: Extracellular Matrix*/metabolism , Extracellular Matrix*/genetics , Single-Cell Analysis*/methods , Data Mining*/methods , Sequence Analysis, RNA*/methods , Software*, Humans ; Extracellular Matrix Proteins/metabolism ; Extracellular Matrix Proteins/genetics

The effect of macromolecular crowders on deposition of extracellular matrix in astrocyte cultures.

Authors: Nemati S Kilcoyne M Zeugolis D et al.

Source: Cell and tissue research [Cell Tissue Res] 2025 Aug; Vol. 401 (2), pp. 129-143. Date of Electronic Publication: 2025 May 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417625 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0878 (Electronic) Linking ISSN: 0302766X NLM ISO Abbreviation: Cell Tissue Res Subsets: MEDLINE

MeSH Terms: Astrocytes*/metabolism , Astrocytes*/cytology , Astrocytes*/drug effects , Extracellular Matrix*/metabolism , Extracellular Matrix*/drug effects , Macromolecular Substances*/pharmacology , Macromolecular Substances*/metabolism, Animals ; Cells, Cultured ; Cell Survival/drug effects ; Mice ; Fibronectins/metabolism ; Extracellular Matrix Proteins/metabolism ; Rats

Notum as a Crucial Regulator of Matrix Integrity in Dentinogenesis.

Authors: Choi H Jeong JK Adasooriya D et al.

Source: Journal of cellular physiology [J Cell Physiol] 2025 Jul; Vol. 240 (7), pp. e70070.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

MeSH Terms: Dentinogenesis*/genetics , Dentinogenesis*/physiology , Dentin*/metabolism , Extracellular Matrix*/metabolism, Animals ; Wnt Signaling Pathway ; Odontoblasts/metabolism ; Cell Differentiation ; Mice ; Extracellular Matrix Proteins/metabolism ; Extracellular Matrix Proteins/genetics ; Mice, Knockout ; Sialoglycoproteins/metabolism ; Sialoglycoproteins/genetics ; Phosphoproteins/metabolism ; Phosphoproteins/genetics ; beta Catenin/metabolism ; Dental Pulp/metabolism ; Odontogenesis

Clicktetrazine dECM-alginate hydrogels for injectable, mechanically mimetic, and biologically active vocal fold biomaterials.

Authors: Brown M Okuyama H Li L et al.

Source: Biomaterials [Biomaterials] 2026 Feb; Vol. 325, pp. 123590. Date of Electronic Publication: 2025 Aug 05.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE

MeSH Terms: Hydrogels*/chemistry , Alginates*/chemistry , Vocal Cords*/drug effects , Vocal Cords*/physiology , Biocompatible Materials*/chemistry , Decellularized Extracellular Matrix*/chemistry, Animals ; Humans ; Rats ; Rats, Sprague-Dawley ; Click Chemistry ; Injections ; Extracellular Matrix/chemistry ; Fibroblasts/cytology